ABSTRACT MATERIALS AND METHODS RESULTS DISCUSSION CONCLUSIONS ACKNOWLEDGMENTS REFERENCES CONTACT



ABSTRACT

Selenoproteins are a type of peptides which contain selenium in their structure through the incorporation of selenocysteine (Sec or also U). Selenocysteine is a particular amino acid which is codified by UGA which normally corresponds to a Stop codon. Due to misinterpretation of the codon as a termination signal and the lack of recognition of U as an amino acid in common programmes used in genome analysis, identification of selenoproteins is difficult.

The main aim of this project is to identify and predict selenoproteins present in Neophocaena asiaeorientalis, a finless porpoise that inhabits the eastern seas of Asia. In order to do so, we compared Neophocaena's genome sequence with selenoproteins annotated in Homo sapiens by using a combination of different alignment and sequence extraction tools merged into a single program.