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The results obtained when predicting homologous selenoproteins in the Haplochromis burtoni genome are exposed extensively below. One selenoprotein of each type is discussed individually.

We can call selenoprotein a given protein that has a GAP (selnocysteine) aligned to an X (which was a U in the query protein) in the t-coffee documents, has a strong alignment score, high e-value and contains a SECIS element. Moreover, this statement becomes reinforced when there is a match in SEBLASTIAN. On the other hand, we will talk about an homologous cysteine protein when the given protein usually has a conserved the SECIS element, but instead of having a selenocysteine presents a cysteine amino acid. Finally, a third possible scenario would be that no homologous protein exists in the genome of the Haplochromis burtoni, as a result of loss during evolution. This third scenario will be named as non-predicted selenoprotein.

The main results are summarized in the following table. In addition, the files obtained when performing the analysis are also presented here. The correspondence between the icons and the meanings is the following:




Icon Meaning
Human protein
Zebra fish protein
Correctly predicted
Not correctly predicted



Name Protein sequence Residue tBLASTn Scaffold Exons Exonerate Gene Location Predicted protein T-Coffee Score Seblastian SECIs
DI Sec JAGKPV010000251.1 735980-841340(-) 976
DI1 Sec JAGKPV010000086.1 678892-779506(+) 981
DI2 Sec JAGKPV010000251.1 735977-841340(-) 972
DI3 Sec JAGKPV010000251.1 970733-1071461(+) 987
eEFsec Cys JAGKPV010000177.1 948051-1059169(-) 992
Fep15 Sel JAGKPV010000111.1 961998-1063263(-) 992
GPx1 Sel JAGKPV010000177.1 419878-521041(+) 987
GPx2 Sel JAGKPV010000016.1 2764710-2865584(-) 995
GPx3 Sel JAGKPV010000019.1 3985595-4083241(+) 996
GPx4 Sel JAGKPV010000041.1 1273227-1373987(-) 997
GPx5 Sel JAGKPV010000019.1 3985601-4083241(+) 989
GPx6 Sel JAGKPV010000019.1 3985601-4083241(+) 985
GPx7 Cys JAGKPV010000054.1 1366592-1468524(+) 993
GPx8 Cys JAGKPV010001001.1 753-97351(-) 983
MsrA Cys JAGKPV010000093.1 44397-205051(+) 999
PSTK Cys JAGKPV010000037.1 1881001-1982603(+) 958
SBP2 Cys JAGKPV010000263.1 333501-437078(-) 989
SECp43 Cys JAGKPV010000243.1 383885-489668(-) 976
SecS Cys JAGKPV010000102.1 1-71043(-) 1000
Sel15 Sel JAGKPV010000266.1 553559-657888(+) 994
SelH Sel JAGKPV010000004.1 5388753-5489092(-) 962
SelI Cys JAGKPV010000028.1 3189756-3294873(-) 992
SelJ Sel JAGKPV010000172.1 320935-423268(-) 968
SelK Sel JAGKPV010000060.1 1628708-1728803(+) 970
SelL Cys JAGKPV010000435.1 345199-445784(-) 998
SelM Sel JAGKPV010000018.1 3234933-3337138(-) 988
SelN Sel JAGKPV010000086.1 425700-530833(-) 998
SelO Sel JAGKPV010000127.1 1365144-1470208(-) 998
SelP Sel JAGKPV010000034.1 1190481-1291306(-) 988
SelR Sel JAGKPV010000162.1 1270766-1371787(+) 993
SelR1 Sel JAGKPV010000081.1 1126717-1227236(-) 992
SelR2 Cys JAGKPV010000001.1 5475836-5576976(+) 999
SelR3 Cys JAGKPV010000173.1 841460-944785(-) 974
SelS Cys JAGKPV010001437.1 1-47588(-) 962
SelT Sel JAGKPV010000601.1 146195-263507(-) 995
SelU Sel JAGKPV010000006.1 3629791-3731361(+) 990
SelU1 Sel JAGKPV010000006.1 3629785-3731165(+) 989
SelU2 Cys JAGKPV010000034.1 1811739-1912297(+) 999
SelU3 Cys JAGKPV010000378.1 124872-225078(-) 995
SelW Sel JAGKPV010000052.1 963082-1063622(-) 991
SelW2 Sel JAGKPV010000052.1 963183-1063362(-) 894
SPS Cys JAGKPV010000179.1 381072-485129(-) 1000
SPS1 Cys JAGKPV010000179.1 381072-485129(-) 1000
SPS2 Sel JAGKPV010000482.1 1-57580(-) 969
TR1 Sel JAGKPV010000097.1 713972-819571(+) 998
TR2 Sel JAGKPV010000226.1 229234-346117(+) 999
TR3 Cys JAGKPV010000097.1 713948-819568(+) 999
Project Developed by Joan Magrinyà, Daniel Ramirez, Sara Rebollo & Laia Torres