Results

To see the current selenoprotein sequence and SNPs, click here.

This selenoprotein gene contains 9 SNPs in its sequence.

Only two of them are significant to our current project. The first one is r11720307, a G/T transversion, resulting in a aminoacidic change from Arginine(R) to Serine(S).

The second one, r11562, is located in 3'-UTR. Though this change is located within the secis element sequence, it does not affect any of the critical positions for this structure.

The rest of SNPs found in this gene are not significant to this project. Nevertheless, we did not check whether the ones found within introns were altering the splicing sites.

To see all data about the SNPs in selenoprotein K sequence click here

• Selenoprotein H

To see the current selenoprotein sequence and SNPs, click here.

This selenoprotein gene contains 13 SNPs in its sequence.

Three of them, rs17152073, rs12271969 and rs11229113, are located in the 3' UTR region of the gene. Thus, they could be affecting the critical positions in the secis element. That's not the case, as we checked using Secissearch.

The SNPs rs11552988 and rs11552989 have two alleles, C/T, and both result in a non synonimous substitution of a Arginine(R) to Histidine(H) in exons 1 and 2, respectively.

The rest of SNPs found in this gene are not significant to this project. Nevertheless, we did not check whether the ones found within introns were altering the splicing sites.

To see all data about the SNPs in selenoprotein H sequence click here

• Selenoprotein V

To see the current selenoprotein sequence and SNPs, click here.

This selenoprotein gene contains only 1 characterized SNP in its sequence.

It is a variation in intron 5 which shows two alleles: C/T. Even though we have not checked this possibility, this SNP might be affecting the splicing of the intron.

To see all data about the SNPs in selenoprotein V sequence click here