RID: 1069694397-9914-17664825597.BLASTQ3 Query= HS307871 (4514 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,544,637 sequences; 504,792,447 total letters Taxonomy reports
Query= HS307871 (4514 letters)
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF 1,544,637 sequences; 504,792,447 total letters Taxonomy reports
Related Structures Score E Sequences producing significant alignments: (bits) Value gi|2507533|sp|P06132|DCUP_HUMAN Uroporphyrinogen decarboxyl... 215 5e-54 gi|12804699|gb|AAH01778.1| Uroporphyrinogen decarboxylase [... 215 5e-54 gi|9845522|ref|NP_000365.2| uroporphyrinogen decarboxylase;... 215 5e-54 gi|18158958|pdb|1JPH|A Chain A, Ile260thr Mutant Of Human U... 215 5e-54 gi|18158959|pdb|1JPI|A Chain A, Phe232leu Mutant Of Human U... 215 5e-54 gi|30584783|gb|AAP36644.1| Homo sapiens uroporphyrinogen de... 215 5e-54 gi|18158960|pdb|1JPK|A Chain A, Gly156asp Mutant Of Human U... 213 3e-53 gi|88979|pir||A24411 uroporphyrinogen decarboxylase (EC 4.1... 211 1e-52 gi|340183|gb|AAB59456.1| uroporphyrinogen decarboxylase 206 3e-51 gi|27527067|emb|CAC82649.1| uroporphyrinogen decarboxylase ... 206 4e-51 gi|14198090|gb|AAH08109.1| Uroporphyrinogen decarboxylase [... 198 7e-49 gi|6678517|ref|NP_033504.1| uroporphyrinogen decarboxylase ... 197 2e-48 gi|34870275|ref|XP_342888.1| similar to uroporphyrinogen de... 196 3e-48 gi|225691|prf||1310344A decarboxylase,uroporphyrinogen 189 5e-46 gi|416892|sp|P32362|DCUP_RAT Uroporphyrinogen decarboxylase... 187 2e-45 gi|18859531|ref|NP_571422.1| uroporphyrinogen decarboxylase... 147 2e-33 gi|19075585|ref|NP_588085.1| probable uroporphyrinogen deca... 127 2e-27 gi|4140696|gb|AAD04168.1| uroporphyrinogen decarboxylase [H... 118 9e-25 gi|6320252|ref|NP_010332.1| fifth enzyme in the heme biosyn... 109 4e-22 gi|31240435|ref|XP_320631.1| ENSANGP00000021292 [Anopheles ... 109 5e-22 gi|19921920|ref|NP_610501.1| CG1818-PA [Drosophila melanoga... 107 2e-21 gi|21430840|gb|AAM51098.1| SD19419p [Drosophila melanogaster] 107 2e-21 gi|4140695|gb|AAD04167.1| uroporphyrinogen decarboxylase [H... 104 2e-20 gi|3915203|sp|O18601|DCUP_DROVI Uroporphyrinogen decarboxyl... 103 4e-20 gi|32418962|ref|XP_329959.1| hypothetical protein [Neurospo... 101 1e-19 gi|38110215|gb|EAA55971.1| hypothetical protein MG01622.4 [... 101 1e-19 gi|21674849|ref|NP_662914.1| uroporphyrinogen decarboxylase... 91 3e-16 gi|21232275|ref|NP_638192.1| uroporphyrinogen decarboxylase... 88 1e-15 gi|21243740|ref|NP_643322.1| uroporphyrinogen decarboxylase... 87 4e-15 gi|28872231|ref|NP_794850.1| uroporphyrinogen decarboxylase... 85 1e-14 gi|16123871|ref|NP_407184.1| uroporphyrinogen decarboxylase... 85 1e-14 gi|33598623|ref|NP_886266.1| uroporphyrinogen decarboxylase... 84 2e-14 gi|33603574|ref|NP_891134.1| uroporphyrinogen decarboxylase... 84 2e-14 gi|23469744|ref|ZP_00125078.1| COG0407: Uroporphyrinogen-II... 84 2e-14 gi|33594189|ref|NP_881833.1| uroporphyrinogen decarboxylase... 83 5e-14 gi|23104868|ref|ZP_00091328.1| COG0407: Uroporphyrinogen-II... 83 5e-14 gi|22994377|ref|ZP_00038883.1| COG0407: Uroporphyrinogen-II... 83 5e-14 gi|23138367|ref|ZP_00120028.1| COG0407: Uroporphyrinogen-II... 82 7e-14 gi|15603599|ref|NP_246673.1| UroD [Pasteurella multocida] >... 82 7e-14 gi|28899690|ref|NP_799295.1| uroporphyrinogen decarboxylase... 80 1e-13 gi|26991750|ref|NP_747175.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|409791|gb|AAC43095.1| uroporphyrinogen decarboxylase 78 2e-13 gi|34496577|ref|NP_900792.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|15792567|ref|NP_282390.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|37524498|ref|NP_927842.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|28198490|ref|NP_778804.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|15640359|ref|NP_229986.1| uroporphyrinogen decarboxylase... 77 2e-13 gi|23814028|sp|Q9KV26|DCUP_VIBCH Uroporphyrinogen decarboxy... 77 2e-13 gi|15834174|ref|NP_312947.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|16131827|ref|NP_418425.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|26250768|ref|NP_756808.1| Uroporphyrinogen decarboxylase... 78 2e-13 gi|15804588|ref|NP_290629.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|24115281|ref|NP_709791.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|29653627|ref|NP_819319.1| uroporphyrinogen decarboxylase... 80 3e-13 gi|22996471|ref|ZP_00040726.1| COG0407: Uroporphyrinogen-II... 80 3e-13 gi|24372030|ref|NP_716072.1| uroporphyrinogen decarboxylase... 77 3e-13 gi|16762290|ref|NP_457907.1| uroporphyrinogen decarboxylase... 77 3e-13 gi|23058150|ref|ZP_00083245.1| COG0407: Uroporphyrinogen-II... 80 3e-13 gi|23028166|ref|ZP_00066577.1| COG0407: Uroporphyrinogen-II... 77 5e-13 gi|24461655|gb|AAN62224.1| putative uroporphyrinogen decarb... 76 6e-13 gi|15676679|ref|NP_273823.1| uroporphyrinogen decarboxylase... 79 6e-13 gi|30248462|ref|NP_840532.1| Uroporphyrinogen decarboxylase... 77 8e-13 gi|27364622|ref|NP_760150.1| Uroporphyrinogen-III decarboxy... 78 1e-12 gi|15600227|ref|NP_253721.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|15837933|ref|NP_298621.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|16767421|ref|NP_463036.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|32034577|ref|ZP_00134733.1| COG0407: Uroporphyrinogen-II... 79 1e-12 gi|1750399|gb|AAB39261.1| HemE homolog [Pseudomonas aerugin... 79 1e-12 gi|15793948|ref|NP_283770.1| putative uroporphyrinogen deca... 77 2e-12 gi|22980669|ref|ZP_00026372.1| COG0407: Uroporphyrinogen-II... 77 4e-12 gi|23000993|ref|ZP_00044909.1| COG0407: Uroporphyrinogen-II... 77 4e-12 gi|22984033|ref|ZP_00029193.1| COG0407: Uroporphyrinogen-II... 76 5e-12 gi|23468082|ref|ZP_00123649.1| COG0407: Uroporphyrinogen-II... 62 2e-11 gi|23054304|ref|ZP_00080471.1| COG0407: Uroporphyrinogen-II... 73 4e-11 gi|34556803|ref|NP_906618.1| UROPORPHYRINOGEN DECARBOXYLASE... 71 2e-10 gi|22970842|ref|ZP_00017866.1| hypothetical protein [Chloro... 71 2e-10 gi|15806153|ref|NP_294857.1| uroporphyrinogen decarboxylase... 55 2e-09 gi|216564|dbj|BAA02148.1| uroporphyrinogen III decarboxylas... 67 2e-09 gi|38233021|ref|NP_938788.1| uroporphyrinogen decarboxylase... 67 4e-09 gi|21224363|ref|NP_630142.1| uroporphyrinogen decarboxylase... 66 7e-09 gi|29828770|ref|NP_823404.1| putative uroporphyrinogen deca... 65 1e-08 gi|699194|gb|AAA62959.1| hemE [Mycobacterium leprae] 62 1e-07 gi|15827506|ref|NP_301769.1| uroporphyrinogen decarboxylase... 62 1e-07 gi|8928071|sp|Q9RV96|DCUP_DEIRA Uroporphyrinogen decarboxyl... 55 1e-07 gi|23502914|ref|NP_699041.1| uroporphyrinogen decarboxylase... 53 2e-07 gi|32267372|ref|NP_861404.1| uroporphyrinogen decarboxylase... 61 2e-07 gi|17986285|ref|NP_538919.1| UROPORPHYRINOGEN DECARBOXYLASE... 53 3e-07 gi|32475041|ref|NP_868035.1| uroporphyrinogen III synthase,... 60 3e-07 gi|15842216|ref|NP_337253.1| uroporphyrinogen decarboxylase... 59 1e-06 gi|31793850|ref|NP_856343.1| PUTATIVE UROPORPHYRINOGEN DECA... 59 1e-06 gi|15609815|ref|NP_217194.1| hemE [Mycobacterium tuberculos... 59 1e-06 gi|23019778|ref|ZP_00059487.1| COG0407: Uroporphyrinogen-II... 57 4e-06 gi|33862718|ref|NP_894278.1| Uroporphyrinogen decarboxylase... 55 9e-06 gi|15967094|ref|NP_387447.1| PROBABLE UROPORPHYRINOGEN DECA... 54 2e-05 gi|23005188|ref|ZP_00048138.1| COG0407: Uroporphyrinogen-II... 54 3e-05 gi|33866029|ref|NP_897588.1| Uroporphyrinogen decarboxylase... 52 1e-04 gi|1169255|sp|P42503|DCUP_RHOCA Uroporphyrinogen decarboxyl... 39 1e-04 gi|231982|sp|P16891|DCUP_SYNP7 Uroporphyrinogen decarboxyla... 52 1e-04 gi|37523446|ref|NP_926823.1| uroporphyrinogen decarboxylase... 51 2e-04 gi|33861140|ref|NP_892701.1| Uroporphyrinogen decarboxylase... 50 3e-04 Alignments
Related Structures Score E Sequences producing significant alignments: (bits) Value gi|2507533|sp|P06132|DCUP_HUMAN Uroporphyrinogen decarboxyl... 215 5e-54 gi|12804699|gb|AAH01778.1| Uroporphyrinogen decarboxylase [... 215 5e-54 gi|9845522|ref|NP_000365.2| uroporphyrinogen decarboxylase;... 215 5e-54 gi|18158958|pdb|1JPH|A Chain A, Ile260thr Mutant Of Human U... 215 5e-54 gi|18158959|pdb|1JPI|A Chain A, Phe232leu Mutant Of Human U... 215 5e-54 gi|30584783|gb|AAP36644.1| Homo sapiens uroporphyrinogen de... 215 5e-54 gi|18158960|pdb|1JPK|A Chain A, Gly156asp Mutant Of Human U... 213 3e-53 gi|88979|pir||A24411 uroporphyrinogen decarboxylase (EC 4.1... 211 1e-52 gi|340183|gb|AAB59456.1| uroporphyrinogen decarboxylase 206 3e-51 gi|27527067|emb|CAC82649.1| uroporphyrinogen decarboxylase ... 206 4e-51 gi|14198090|gb|AAH08109.1| Uroporphyrinogen decarboxylase [... 198 7e-49 gi|6678517|ref|NP_033504.1| uroporphyrinogen decarboxylase ... 197 2e-48 gi|34870275|ref|XP_342888.1| similar to uroporphyrinogen de... 196 3e-48 gi|225691|prf||1310344A decarboxylase,uroporphyrinogen 189 5e-46 gi|416892|sp|P32362|DCUP_RAT Uroporphyrinogen decarboxylase... 187 2e-45 gi|18859531|ref|NP_571422.1| uroporphyrinogen decarboxylase... 147 2e-33 gi|19075585|ref|NP_588085.1| probable uroporphyrinogen deca... 127 2e-27 gi|4140696|gb|AAD04168.1| uroporphyrinogen decarboxylase [H... 118 9e-25 gi|6320252|ref|NP_010332.1| fifth enzyme in the heme biosyn... 109 4e-22 gi|31240435|ref|XP_320631.1| ENSANGP00000021292 [Anopheles ... 109 5e-22 gi|19921920|ref|NP_610501.1| CG1818-PA [Drosophila melanoga... 107 2e-21 gi|21430840|gb|AAM51098.1| SD19419p [Drosophila melanogaster] 107 2e-21 gi|4140695|gb|AAD04167.1| uroporphyrinogen decarboxylase [H... 104 2e-20 gi|3915203|sp|O18601|DCUP_DROVI Uroporphyrinogen decarboxyl... 103 4e-20 gi|32418962|ref|XP_329959.1| hypothetical protein [Neurospo... 101 1e-19 gi|38110215|gb|EAA55971.1| hypothetical protein MG01622.4 [... 101 1e-19 gi|21674849|ref|NP_662914.1| uroporphyrinogen decarboxylase... 91 3e-16 gi|21232275|ref|NP_638192.1| uroporphyrinogen decarboxylase... 88 1e-15 gi|21243740|ref|NP_643322.1| uroporphyrinogen decarboxylase... 87 4e-15 gi|28872231|ref|NP_794850.1| uroporphyrinogen decarboxylase... 85 1e-14 gi|16123871|ref|NP_407184.1| uroporphyrinogen decarboxylase... 85 1e-14 gi|33598623|ref|NP_886266.1| uroporphyrinogen decarboxylase... 84 2e-14 gi|33603574|ref|NP_891134.1| uroporphyrinogen decarboxylase... 84 2e-14 gi|23469744|ref|ZP_00125078.1| COG0407: Uroporphyrinogen-II... 84 2e-14 gi|33594189|ref|NP_881833.1| uroporphyrinogen decarboxylase... 83 5e-14 gi|23104868|ref|ZP_00091328.1| COG0407: Uroporphyrinogen-II... 83 5e-14 gi|22994377|ref|ZP_00038883.1| COG0407: Uroporphyrinogen-II... 83 5e-14 gi|23138367|ref|ZP_00120028.1| COG0407: Uroporphyrinogen-II... 82 7e-14 gi|15603599|ref|NP_246673.1| UroD [Pasteurella multocida] >... 82 7e-14 gi|28899690|ref|NP_799295.1| uroporphyrinogen decarboxylase... 80 1e-13 gi|26991750|ref|NP_747175.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|409791|gb|AAC43095.1| uroporphyrinogen decarboxylase 78 2e-13 gi|34496577|ref|NP_900792.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|15792567|ref|NP_282390.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|37524498|ref|NP_927842.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|28198490|ref|NP_778804.1| uroporphyrinogen decarboxylase... 81 2e-13 gi|15640359|ref|NP_229986.1| uroporphyrinogen decarboxylase... 77 2e-13 gi|23814028|sp|Q9KV26|DCUP_VIBCH Uroporphyrinogen decarboxy... 77 2e-13 gi|15834174|ref|NP_312947.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|16131827|ref|NP_418425.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|26250768|ref|NP_756808.1| Uroporphyrinogen decarboxylase... 78 2e-13 gi|15804588|ref|NP_290629.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|24115281|ref|NP_709791.1| uroporphyrinogen decarboxylase... 78 2e-13 gi|29653627|ref|NP_819319.1| uroporphyrinogen decarboxylase... 80 3e-13 gi|22996471|ref|ZP_00040726.1| COG0407: Uroporphyrinogen-II... 80 3e-13 gi|24372030|ref|NP_716072.1| uroporphyrinogen decarboxylase... 77 3e-13 gi|16762290|ref|NP_457907.1| uroporphyrinogen decarboxylase... 77 3e-13 gi|23058150|ref|ZP_00083245.1| COG0407: Uroporphyrinogen-II... 80 3e-13 gi|23028166|ref|ZP_00066577.1| COG0407: Uroporphyrinogen-II... 77 5e-13 gi|24461655|gb|AAN62224.1| putative uroporphyrinogen decarb... 76 6e-13 gi|15676679|ref|NP_273823.1| uroporphyrinogen decarboxylase... 79 6e-13 gi|30248462|ref|NP_840532.1| Uroporphyrinogen decarboxylase... 77 8e-13 gi|27364622|ref|NP_760150.1| Uroporphyrinogen-III decarboxy... 78 1e-12 gi|15600227|ref|NP_253721.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|15837933|ref|NP_298621.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|16767421|ref|NP_463036.1| uroporphyrinogen decarboxylase... 79 1e-12 gi|32034577|ref|ZP_00134733.1| COG0407: Uroporphyrinogen-II... 79 1e-12 gi|1750399|gb|AAB39261.1| HemE homolog [Pseudomonas aerugin... 79 1e-12 gi|15793948|ref|NP_283770.1| putative uroporphyrinogen deca... 77 2e-12 gi|22980669|ref|ZP_00026372.1| COG0407: Uroporphyrinogen-II... 77 4e-12 gi|23000993|ref|ZP_00044909.1| COG0407: Uroporphyrinogen-II... 77 4e-12 gi|22984033|ref|ZP_00029193.1| COG0407: Uroporphyrinogen-II... 76 5e-12 gi|23468082|ref|ZP_00123649.1| COG0407: Uroporphyrinogen-II... 62 2e-11 gi|23054304|ref|ZP_00080471.1| COG0407: Uroporphyrinogen-II... 73 4e-11 gi|34556803|ref|NP_906618.1| UROPORPHYRINOGEN DECARBOXYLASE... 71 2e-10 gi|22970842|ref|ZP_00017866.1| hypothetical protein [Chloro... 71 2e-10 gi|15806153|ref|NP_294857.1| uroporphyrinogen decarboxylase... 55 2e-09 gi|216564|dbj|BAA02148.1| uroporphyrinogen III decarboxylas... 67 2e-09 gi|38233021|ref|NP_938788.1| uroporphyrinogen decarboxylase... 67 4e-09 gi|21224363|ref|NP_630142.1| uroporphyrinogen decarboxylase... 66 7e-09 gi|29828770|ref|NP_823404.1| putative uroporphyrinogen deca... 65 1e-08 gi|699194|gb|AAA62959.1| hemE [Mycobacterium leprae] 62 1e-07 gi|15827506|ref|NP_301769.1| uroporphyrinogen decarboxylase... 62 1e-07 gi|8928071|sp|Q9RV96|DCUP_DEIRA Uroporphyrinogen decarboxyl... 55 1e-07 gi|23502914|ref|NP_699041.1| uroporphyrinogen decarboxylase... 53 2e-07 gi|32267372|ref|NP_861404.1| uroporphyrinogen decarboxylase... 61 2e-07 gi|17986285|ref|NP_538919.1| UROPORPHYRINOGEN DECARBOXYLASE... 53 3e-07 gi|32475041|ref|NP_868035.1| uroporphyrinogen III synthase,... 60 3e-07 gi|15842216|ref|NP_337253.1| uroporphyrinogen decarboxylase... 59 1e-06 gi|31793850|ref|NP_856343.1| PUTATIVE UROPORPHYRINOGEN DECA... 59 1e-06 gi|15609815|ref|NP_217194.1| hemE [Mycobacterium tuberculos... 59 1e-06 gi|23019778|ref|ZP_00059487.1| COG0407: Uroporphyrinogen-II... 57 4e-06 gi|33862718|ref|NP_894278.1| Uroporphyrinogen decarboxylase... 55 9e-06 gi|15967094|ref|NP_387447.1| PROBABLE UROPORPHYRINOGEN DECA... 54 2e-05 gi|23005188|ref|ZP_00048138.1| COG0407: Uroporphyrinogen-II... 54 3e-05 gi|33866029|ref|NP_897588.1| Uroporphyrinogen decarboxylase... 52 1e-04 gi|1169255|sp|P42503|DCUP_RHOCA Uroporphyrinogen decarboxyl... 39 1e-04 gi|231982|sp|P16891|DCUP_SYNP7 Uroporphyrinogen decarboxyla... 52 1e-04 gi|37523446|ref|NP_926823.1| uroporphyrinogen decarboxylase... 51 2e-04 gi|33861140|ref|NP_892701.1| Uroporphyrinogen decarboxylase... 50 3e-04
>gi|2507533|sp|P06132|DCUP_HUMAN Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|3660278|pdb|1URO|A Chain A, Uroporphyrinogen Decarboxylase gi|2905794|gb|AAC03563.1| uroporphyrinogen decarboxylase [Homo sapiens] Length = 367 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
Score = 137 bits (346), Expect(2) = 7e-40 Identities = 79/133 (59%), Positives = 80/133 (60%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+ Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 280 VGLDWTVAPKKAR 292
Score = 118 bits (296), Expect = 9e-25 Identities = 55/59 (93%), Positives = 56/59 (94%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN Sbjct: 309 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 87.0 bits (214), Expect(3) = 2e-34 Identities = 37/37 (100%), Positives = 37/37 (100%) Frame = +3 Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 2e-34 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 52.4 bits (124), Expect(2) = 7e-40 Identities = 23/24 (95%), Positives = 24/24 (100%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQGNLDPCALYASE Sbjct: 291 ARECVGKTVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 2e-34 Identities = 22/23 (95%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRF LDAAIIFSDILVVPQ Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
>gi|12804699|gb|AAH01778.1| Uroporphyrinogen decarboxylase [Homo sapiens] gi|30582313|gb|AAP35383.1| uroporphyrinogen decarboxylase [Homo sapiens] Length = 367 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
Score = 137 bits (346), Expect(2) = 7e-39 Identities = 79/133 (59%), Positives = 80/133 (60%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+ Sbjct: 213 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 259 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 280 VGLDWTVAPKKAR 292
Score = 48.9 bits (115), Expect(2) = 7e-39 Identities = 22/24 (91%), Positives = 23/24 (95%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQ NLDPCALYASE Sbjct: 291 ARECVGKTVTLQVNLDPCALYASE 314
>gi|9845522|ref|NP_000365.2| uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase [Homo sapiens] gi|7436550|pir||G02786 uroporphyrinogen decarboxylase - human gi|1322019|gb|AAC50482.1| uroporphyrinogen decarboxylase gi|1418944|emb|CAA61540.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151813|gb|AAD04571.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151815|gb|AAD04572.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151817|gb|AAD04573.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151819|gb|AAD04574.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151821|gb|AAD04575.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151823|gb|AAD04576.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151825|gb|AAD04577.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151827|gb|AAD04578.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151829|gb|AAD04579.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151831|gb|AAD04580.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151833|gb|AAD04581.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151835|gb|AAD04582.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151837|gb|AAD04583.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151839|gb|AAD04584.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151841|gb|AAD04585.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151843|gb|AAD04586.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151845|gb|AAD04587.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151847|gb|AAD04588.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151849|gb|AAD04589.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|4151851|gb|AAD04590.1| uroporphyrinogen decarboxylase [Homo sapiens] gi|31323304|gb|AAP44118.1| uroporphyrinogen decarboxylase [Homo sapiens] Length = 367 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
Score = 87.0 bits (214), Expect(3) = 3e-35 Identities = 37/37 (100%), Positives = 37/37 (100%) Frame = +3 Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 8 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 3e-35 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 47.0 bits (110), Expect(3) = 3e-35 Identities = 23/23 (100%), Positives = 23/23 (100%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRFLLDAAIIFSDILVVPQ Sbjct: 70 LQPLRRFLLDAAIIFSDILVVPQ 92
>gi|18158958|pdb|1JPH|A Chain A, Ile260thr Mutant Of Human Urod, Human Uroporphyrinogen Iii Decarboxylase Length = 388 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 113 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 172 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 173 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 193 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 194 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 233
Score = 136 bits (342), Expect(2) = 2e-39 Identities = 79/133 (59%), Positives = 79/133 (59%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM Sbjct: 234 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM-------------- 279 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 I FAKDGHFALEELAQAGYEV Sbjct: 280 ---------------------------------------ITFAKDGHFALEELAQAGYEV 300 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 301 VGLDWTVAPKKAR 313
Score = 118 bits (296), Expect = 9e-25 Identities = 55/59 (93%), Positives = 56/59 (94%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN Sbjct: 330 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 388
Score = 87.0 bits (214), Expect(3) = 2e-34 Identities = 37/37 (100%), Positives = 37/37 (100%) Frame = +3 Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 29 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 65
Score = 60.8 bits (146), Expect(3) = 2e-34 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 66 EFRETRAAQDFFSTCRSPEACCELTLQ 92
Score = 52.4 bits (124), Expect(2) = 2e-39 Identities = 23/24 (95%), Positives = 24/24 (100%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQGNLDPCALYASE Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
Score = 44.3 bits (103), Expect(3) = 2e-34 Identities = 22/23 (95%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRF LDAAIIFSDILVVPQ Sbjct: 91 LQPLRRFPLDAAIIFSDILVVPQ 113
>gi|18158959|pdb|1JPI|A Chain A, Phe232leu Mutant Of Human Urod, Human Uroporphyrinogen Iii Decarboxylase Length = 388 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 113 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 172 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 173 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 193 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 194 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 233
Score = 135 bits (340), Expect(2) = 3e-39 Identities = 78/133 (58%), Positives = 79/133 (59%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLFNK ALPYIRDVAKQVKARLREAGLAPVPM+ Sbjct: 234 ALQLFESHAGHLGPQLFNKLALPYIRDVAKQVKARLREAGLAPVPMI------------- 280 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 281 ----------------------------------------IFAKDGHFALEELAQAGYEV 300 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 301 VGLDWTVAPKKAR 313
Score = 52.4 bits (124), Expect(2) = 3e-39 Identities = 23/24 (95%), Positives = 24/24 (100%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQGNLDPCALYASE Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
>gi|30584783|gb|AAP36644.1| Homo sapiens uroporphyrinogen decarboxylase [synthetic construct] Length = 368 Score = 215 bits (548), Expect = 5e-54 Identities = 119/160 (74%), Positives = 120/160 (75%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
>gi|18158960|pdb|1JPK|A Chain A, Gly156asp Mutant Of Human Urod, Human Uroporphyrinogen Iii Decarboxylase Length = 388 Score = 213 bits (541), Expect = 3e-53 Identities = 118/160 (73%), Positives = 119/160 (74%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 113 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 172 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFA AP W + MTYMVEGGGSS Sbjct: 173 IGFADAP---------------WTL------------------------MTYMVEGGGSS 193 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 194 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 233
Score = 137 bits (346), Expect(2) = 7e-40 Identities = 79/133 (59%), Positives = 80/133 (60%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM+ Sbjct: 234 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMI------------- 280 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 281 ----------------------------------------IFAKDGHFALEELAQAGYEV 300 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 301 VGLDWTVAPKKAR 313
Score = 52.4 bits (124), Expect(2) = 7e-40 Identities = 23/24 (95%), Positives = 24/24 (100%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQGNLDPCALYASE Sbjct: 312 ARECVGKTVTLQGNLDPCALYASE 335
>gi|88979|pir||A24411 uroporphyrinogen decarboxylase (EC 4.1.1.37) - human gi|340181|gb|AAA61258.1| uroporphyrinogen decarboxylase (EC 4.1.1.37) Length = 367 Score = 211 bits (536), Expect = 1e-52 Identities = 117/160 (73%), Positives = 118/160 (73%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVP KGPSFPEPLREEQDLE LRDPEVVASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPSKGPSFPEPLREEQDLEALRDPEVVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 173 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 212
>gi|340183|gb|AAB59456.1| uroporphyrinogen decarboxylase Length = 161 Score = 206 bits (524), Expect = 3e-51 Identities = 114/158 (72%), Positives = 116/158 (73%) Frame = +1 Query: 2440 GMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGF 2619 GMEVTMVP KGPSFPEPLREEQDLE LRDPEVVASELGYVFQAITLTRQRLAGRVPLIGF Sbjct: 1 GMEVTMVPSKGPSFPEPLREEQDLEALRDPEVVASELGYVFQAITLTRQRLAGRVPLIGF 60 Query: 2620 AGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSSTMA 2799 AGAP W + MTYMVEGGGSSTMA Sbjct: 61 AGAP---------------WTL------------------------MTYMVEGGGSSTMA 81 Query: 2800 QAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 QAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ+ Sbjct: 82 QAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQL 119
Score = 92.0 bits (227), Expect = 9e-17 Identities = 44/44 (100%), Positives = 44/44 (100%) Frame = +3 Query: 3285 QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 3416 QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM Sbjct: 118 QLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 161
>gi|27527067|emb|CAC82649.1| uroporphyrinogen decarboxylase [Ovis aries] Length = 367 Score = 206 bits (523), Expect = 4e-51 Identities = 113/160 (70%), Positives = 117/160 (73%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQ+LAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREERDLERLRDPATVASELGYVFQAITLTRQQLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGGGSS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGGSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TM+QAKRWLYQRPQASHQLLRILTDALVPYLVGQV AGAQ Sbjct: 173 TMSQAKRWLYQRPQASHQLLRILTDALVPYLVGQVAAGAQ 212
Score = 127 bits (319), Expect(2) = 2e-35 Identities = 73/133 (54%), Positives = 79/133 (59%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLGPQLF+KFALPYIRDV+K+VKA L+EAGLAPVPM+ Sbjct: 213 ALQLFESHAGHLGPQLFSKFALPYIRDVSKRVKAGLQEAGLAPVPMI------------- 259 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAP+KAR Sbjct: 280 VGLDWTVAPEKAR 292
Score = 110 bits (275), Expect = 2e-22 Identities = 51/59 (86%), Positives = 55/59 (93%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN Sbjct: 309 ALYASEEEIGKLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 367
Score = 89.4 bits (220), Expect(3) = 4e-35 Identities = 38/39 (97%), Positives = 39/39 (100%) Frame = +3 Query: 1743 ARPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 +RPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 6 SRPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 4e-35 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 47.8 bits (112), Expect(2) = 2e-35 Identities = 22/24 (91%), Positives = 23/24 (95%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RE VGKTVTLQGNLDPCALYASE Sbjct: 291 ARERVGKTVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 4e-35 Identities = 22/23 (95%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRF LDAAIIFSDILVVPQ Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
>gi|14198090|gb|AAH08109.1| Uroporphyrinogen decarboxylase [Mus musculus] Length = 367 Score = 198 bits (504), Expect = 7e-49 Identities = 109/160 (68%), Positives = 113/160 (70%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREE+DLERLRDP ASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGMEVTMVPGKGPSFPEPLREERDLERLRDPAAAASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGG SS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGSSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASH+LL ILTD LVPYL+GQV AGAQ Sbjct: 173 TMAQAKRWLYQRPQASHKLLGILTDVLVPYLIGQVAAGAQ 212
Score = 124 bits (311), Expect(2) = 6e-34 Identities = 72/133 (54%), Positives = 78/133 (58%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGLAPVPM+ Sbjct: 213 ALQLFESHAGHLGTELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMI------------- 259 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 280 VGLDWTVAPKKAR 292
Score = 109 bits (272), Expect = 5e-22 Identities = 51/59 (86%), Positives = 54/59 (91%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QMLDDFGP RYIANLGHGLYPDMDPE VGAFVDAVHKHSRLLRQN Sbjct: 309 ALYASEEEIGRLVQQMLDDFGPQRYIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN 367
Score = 82.0 bits (201), Expect(3) = 6e-33 Identities = 35/36 (97%), Positives = 35/36 (97%) Frame = +3 Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 9 QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 6e-33 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 45.8 bits (107), Expect(2) = 6e-34 Identities = 21/24 (87%), Positives = 22/24 (91%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RE VGK VTLQGNLDPCALYASE Sbjct: 291 ARERVGKAVTLQGNLDPCALYASE 314
Score = 44.3 bits (103), Expect(3) = 6e-33 Identities = 22/23 (95%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRF LDAAIIFSDILVVPQ Sbjct: 70 LQPLRRFPLDAAIIFSDILVVPQ 92
>gi|6678517|ref|NP_033504.1| uroporphyrinogen decarboxylase [Mus musculus] gi|2501645|sp|P70697|DCUP_MOUSE Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|7436557|pir||T10088 uroporphyrinogen decarboxylase (EC 4.1.1.37) - mouse gi|1498643|gb|AAB18294.1| uroporphyrinogen decarboxylase Length = 367 Score = 197 bits (500), Expect = 2e-48 Identities = 108/160 (67%), Positives = 113/160 (70%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALG+EVTMVPGKGPSFPEPLREE+DLERLRDP ASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALGIEVTMVPGKGPSFPEPLREERDLERLRDPAAAASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGG SS Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGSSS 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQRPQASH+LL ILTD LVPYL+GQV AGAQ Sbjct: 173 TMAQAKRWLYQRPQASHKLLGILTDVLVPYLIGQVAAGAQ 212
Score = 105 bits (263), Expect = 6e-21 Identities = 50/59 (84%), Positives = 53/59 (89%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QMLDDFGP R IANLGHGLYPDMDPE VGAFVDAVHKHSRLLRQN Sbjct: 309 ALYASEEEIGRLVQQMLDDFGPQRSIANLGHGLYPDMDPERVGAFVDAVHKHSRLLRQN 367
>gi|34870275|ref|XP_342888.1| similar to uroporphyrinogen decarboxylase [Rattus norvegicus] Length = 374 Score = 196 bits (498), Expect = 3e-48 Identities = 108/160 (67%), Positives = 114/160 (71%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGMEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQ+LAGRVPL Sbjct: 99 QALGMEVTMVPGKGPSFPEPLREERDLERLRDPAAVASELGYVFQAITLTRQQLAGRVPL 158 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGG SS Sbjct: 159 IGFAGAP---------------WTL------------------------MTYMVEGGSSS 179 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQ+P ASH+LL ILTDALVPYL+GQV AGAQ Sbjct: 180 TMAQAKRWLYQKPLASHKLLGILTDALVPYLIGQVAAGAQ 219
Score = 124 bits (311), Expect(2) = 2e-34 Identities = 72/133 (54%), Positives = 78/133 (58%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGLAPVPM+ Sbjct: 220 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLAPVPMI------------- 266 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 267 ----------------------------------------IFAKDGHFALEELAQAGYEV 286 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 287 VGLDWTVAPKKAR 299
Score = 110 bits (275), Expect = 2e-22 Identities = 51/59 (86%), Positives = 55/59 (93%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN Sbjct: 316 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 374
Score = 85.5 bits (210), Expect(3) = 1e-33 Identities = 38/41 (92%), Positives = 38/41 (92%) Frame = +3 Query: 1737 LIARPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LI R Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 11 LIRRLQNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 51
Score = 60.8 bits (146), Expect(3) = 1e-33 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 52 EFRETRAAQDFFSTCRSPEACCELTLQ 78
Score = 47.8 bits (112), Expect(2) = 2e-34 Identities = 22/24 (91%), Positives = 23/24 (95%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RE VGKTVTLQGNLDPCALYASE Sbjct: 298 ARERVGKTVTLQGNLDPCALYASE 321
Score = 43.1 bits (100), Expect(3) = 1e-33 Identities = 21/23 (91%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLR+F LDAAIIFSDILVVPQ Sbjct: 77 LQPLRKFPLDAAIIFSDILVVPQ 99
>gi|225691|prf||1310344A decarboxylase,uroporphyrinogen Length = 367 Score = 189 bits (479), Expect = 5e-46 Identities = 105/160 (65%), Positives = 110/160 (68%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QAL MEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQRLAGRVPL Sbjct: 92 QALAMEVTMVPGKGPSFPEPLREERDLERLRDPAAVASELGYVFQAITLTRQRLAGRVPL 151 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGG Sbjct: 152 IGFAGAP---------------WTL------------------------MTYMVEGGSFK 172 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQ+P ASH+LL ILT ALVPYL+GQV AGAQ Sbjct: 173 TMAQAKRWLYQKPVASHKLLGILTHALVPYLIGQVAAGAQ 212
Score = 118 bits (295), Expect(2) = 5e-32 Identities = 69/133 (51%), Positives = 76/133 (57%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGL +PM+ Sbjct: 213 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLTRMPMI------------- 259 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 260 ----------------------------------------IFAKDGHFALEELAQAGYEV 279 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 280 VGLDWTVAPKKAR 292
Score = 109 bits (272), Expect = 5e-22 Identities = 50/59 (84%), Positives = 55/59 (93%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAF+DAVHKHSRLLRQN Sbjct: 309 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN 367
Score = 77.0 bits (188), Expect(3) = 4e-31 Identities = 34/36 (94%), Positives = 34/36 (94%) Frame = +3 Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 Q FPELKNDTFLRAA GEETDYTPVWCMRQAGRYLP Sbjct: 9 QNFPELKNDTFLRAATGEETDYTPVWCMRQAGRYLP 44
Score = 60.8 bits (146), Expect(3) = 4e-31 Identities = 27/27 (100%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTLQ Sbjct: 45 EFRETRAAQDFFSTCRSPEACCELTLQ 71
Score = 45.4 bits (106), Expect(2) = 5e-32 Identities = 21/24 (87%), Positives = 22/24 (91%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RE VGKTVTLQG LDPCALYASE Sbjct: 291 AREPVGKTVTLQGELDPCALYASE 314
Score = 43.1 bits (100), Expect(3) = 4e-31 Identities = 21/23 (91%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQP+RRF LDAAIIFSDILVVPQ Sbjct: 70 LQPVRRFPLDAAIIFSDILVVPQ 92
>gi|416892|sp|P32362|DCUP_RAT Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|5524747|emb|CAB50784.1| uroporphyrinogen decarboxylase [Rattus norvegicus] Length = 364 Score = 187 bits (475), Expect = 2e-45 Identities = 104/160 (65%), Positives = 110/160 (68%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QAL MEVTMVPGKGPSFPEPLREE+DLERLRDP VASELGYVFQAITLTRQ+LAGRVPL Sbjct: 89 QALAMEVTMVPGKGPSFPEPLREERDLERLRDPAAVASELGYVFQAITLTRQQLAGRVPL 148 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP W + MTYMVEGG Sbjct: 149 IGFAGAP---------------WTL------------------------MTYMVEGGSFK 169 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 TMAQAKRWLYQ+P ASH+LL ILT ALVPYL+GQV AGAQ Sbjct: 170 TMAQAKRWLYQKPVASHKLLGILTHALVPYLIGQVAAGAQ 209
Score = 118 bits (295), Expect(2) = 5e-32 Identities = 69/133 (51%), Positives = 76/133 (57%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQLFESHAGHLG +LF+KFALPYIRDVAK+VKA L++AGL +PM+ Sbjct: 210 ALQLFESHAGHLGSELFSKFALPYIRDVAKRVKAGLQKAGLTRMPMI------------- 256 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 IFAKDGHFALEELAQAGYEV Sbjct: 257 ----------------------------------------IFAKDGHFALEELAQAGYEV 276 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWTVAPKKAR Sbjct: 277 VGLDWTVAPKKAR 289
Score = 109 bits (272), Expect = 5e-22 Identities = 50/59 (84%), Positives = 55/59 (93%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIG+LV+QML+DFGP RYIANLGHGLYPDMDPEHVGAF+DAVHKHSRLLRQN Sbjct: 306 ALYASEEEIGRLVQQMLNDFGPQRYIANLGHGLYPDMDPEHVGAFLDAVHKHSRLLRQN 364
Score = 82.0 bits (201), Expect(3) = 7e-32 Identities = 35/36 (97%), Positives = 35/36 (97%) Frame = +3 Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 Q FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP Sbjct: 6 QNFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 41
Score = 59.7 bits (143), Expect(3) = 7e-32 Identities = 26/27 (96%), Positives = 27/27 (100%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRETRAAQDFFSTCRSPEACCELTL+ Sbjct: 42 EFRETRAAQDFFSTCRSPEACCELTLE 68
Score = 45.4 bits (106), Expect(2) = 5e-32 Identities = 21/24 (87%), Positives = 22/24 (91%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RE VGKTVTLQG LDPCALYASE Sbjct: 288 AREPVGKTVTLQGELDPCALYASE 311
Score = 42.0 bits (97), Expect(3) = 7e-32 Identities = 20/23 (86%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 L+P+RRF LDAAIIFSDILVVPQ Sbjct: 67 LEPVRRFPLDAAIIFSDILVVPQ 89
>gi|18859531|ref|NP_571422.1| uroporphyrinogen decarboxylase [Danio rerio] gi|20138048|sp|Q9PTS2|DCUP_BRARE Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|6502530|gb|AAF14346.1| uroporphyrinogen decarboxylase [Danio rerio] Length = 369 Score = 147 bits (370), Expect = 2e-33 Identities = 80/160 (50%), Positives = 101/160 (63%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QA+GMEV M PGKGP+FPEPL+E +DL+RL+ V SEL YVF+AITLTR ++ G+VPL Sbjct: 94 QAMGMEVQMCPGKGPTFPEPLKEPEDLQRLKTQVDVYSELDYVFKAITLTRHKIEGKVPL 153 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGF GAP W + M+YM+EGGGS+ Sbjct: 154 IGFTGAP---------------WTL------------------------MSYMIEGGGSA 174 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 T ++AKRWLY+ P+ASH+LL LTD +V YL+GQV AGAQ Sbjct: 175 THSKAKRWLYRYPEASHKLLSQLTDVIVEYLLGQVKAGAQ 214
Score = 88.6 bits (218), Expect(2) = 3e-19 Identities = 48/133 (36%), Positives = 68/133 (51%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWS 3458 ALQ+FESH G LGP F +F+LPY+RD+A++VK +++E+GL VPM+ Sbjct: 215 ALQVFESHTGCLGPVEFKEFSLPYLRDIARRVKDKIKESGLDNVPMI------------- 261 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 +FAKDGH+ LE+L+++ YEV Sbjct: 262 ----------------------------------------VFAKDGHYGLEDLSESAYEV 281 Query: 3639 VGLDWTVAPKKAR 3677 VGLDWT+ P+ AR Sbjct: 282 VGLDWTIDPRSAR 294
Score = 80.5 bits (197), Expect = 3e-13 Identities = 40/68 (58%), Positives = 48/68 (70%) Frame = +3 Query: 4125 GGQRLAGPPVASALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDA 4304 G L G AL +E I ++V++ML+ FG YIANLGHGLYPDMDPE+VGAFV+A Sbjct: 299 GKVSLQGNMDPCALYGTKESISEIVRRMLEGFGTKGYIANLGHGLYPDMDPENVGAFVEA 358 Query: 4305 VHKHSRLL 4328 VH HSR L Sbjct: 359 VHNHSRQL 366
Score = 68.2 bits (165), Expect(3) = 1e-26 Identities = 29/37 (78%), Positives = 33/37 (89%) Frame = +3 Query: 1749 PQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 P+ FPEL+NDTFLRAA GEE ++ PVWCMRQAGRYLP Sbjct: 10 PKDFPELRNDTFLRAARGEEIEHIPVWCMRQAGRYLP 46
Score = 54.7 bits (130), Expect(3) = 1e-26 Identities = 23/27 (85%), Positives = 25/27 (92%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EFRE+RA +DFF TCRSPEACCELTLQ Sbjct: 47 EFRESRAGKDFFETCRSPEACCELTLQ 73
Score = 42.7 bits (99), Expect(3) = 1e-26 Identities = 21/23 (91%), Positives = 21/23 (91%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 LQPLRRF DAAIIFSDILVVPQ Sbjct: 72 LQPLRRFPFDAAIIFSDILVVPQ 94
Score = 32.3 bits (72), Expect(2) = 3e-19 Identities = 13/25 (52%), Positives = 19/25 (76%) Frame = +1 Query: 3772 ASRECVGKTVTLQGNLDPCALYASE 3846 ++R G V+LQGN+DPCALY ++ Sbjct: 292 SARVRTGGKVSLQGNMDPCALYGTK 316
>gi|19075585|ref|NP_588085.1| probable uroporphyrinogen decarboxylase [Schizosaccharomyces pombe] gi|8928074|sp|Q9USJ5|DCUP_SCHPO Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|11267829|pir||T50443 probable uroporphyrinogen decarboxylase [imported] - fission yeast (Schizosaccharomyces pombe) gi|6434013|emb|CAB60679.1| SPCC4B3.05c [Schizosaccharomyces pombe] Length = 370 Score = 127 bits (319), Expect = 2e-27 Identities = 69/161 (42%), Positives = 96/161 (59%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALGM+V M+ KGP FP+PL +D++ L ++++LGYV AI+LTR++L G+VPL Sbjct: 96 QALGMQVVMLEQKGPHFPKPLVVPEDIDLLEKTPNISAKLGYVMDAISLTREKLDGQVPL 155 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 +GF+GAP W + M YM+EGGGS Sbjct: 156 MGFSGAP---------------WTI------------------------MAYMIEGGGSK 176 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 T A+AK WL++ P+ASH+LL+I+TDA V YL+ QV AGAQ+ Sbjct: 177 TFAKAKSWLFRYPEASHKLLKIITDATVSYLIQQVYAGAQL 217
Score = 59.3 bits (142), Expect(2) = 2e-08 Identities = 36/131 (27%), Positives = 57/131 (43%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461 LQ+F+S AG L P+ F ++A PY+ + ++VK L++ VPM Sbjct: 218 LQIFDSWAGELSPEDFTEYAYPYLVRICQEVKQHLKKKKRDEVPM--------------- 262 Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641 I+FAK +A+++L +GY+V+ Sbjct: 263 --------------------------------------IVFAKGAWYAIDQLCDSGYDVI 284 Query: 3642 GLDWTVAPKKA 3674 GLDWTV+PK+A Sbjct: 285 GLDWTVSPKEA 295
Score = 40.4 bits (93), Expect = 0.30 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 2/49 (4%) Frame = +3 Query: 4176 QEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKH 4316 +E I K+M+ DFG + YI NLGHG+ P ++P+ V F++ H++ Sbjct: 319 REIIEARTKEMIQDFGGGKQGYIINLGHGITPGVNPDDVRFFLEKCHQY 367
Score = 38.1 bits (87), Expect(2) = 4e-06 Identities = 20/25 (80%), Positives = 22/25 (88%), Gaps = 2/25 (8%) Frame = +2 Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194 LQP+ RF LLDAAIIFSDILV+PQ Sbjct: 72 LQPVTRFKGLLDAAIIFSDILVIPQ 96
Score = 38.1 bits (87), Expect(2) = 4e-06 Identities = 15/27 (55%), Positives = 19/27 (70%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 E+ + RA Q FF C++PE CELTLQ Sbjct: 47 EYHKLRAKQSFFEMCQTPETACELTLQ 73
Score = 24.6 bits (52), Expect(2) = 2e-08 Identities = 10/17 (58%), Positives = 12/17 (70%) Frame = +1 Query: 3793 KTVTLQGNLDPCALYAS 3843 + VT QGNLDP LY + Sbjct: 302 RRVTFQGNLDPNILYGT 318
>gi|4140696|gb|AAD04168.1| uroporphyrinogen decarboxylase [Homo sapiens] Length = 109 Score = 118 bits (296), Expect = 9e-25 Identities = 55/59 (93%), Positives = 56/59 (94%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 4337 AL +EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN Sbjct: 51 ALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN 109
Score = 72.4 bits (176), Expect(2) = 2e-20 Identities = 34/34 (100%), Positives = 34/34 (100%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR Sbjct: 1 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 34
Score = 52.4 bits (124), Expect(2) = 2e-20 Identities = 23/24 (95%), Positives = 24/24 (100%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASE 3846 +RECVGKTVTLQGNLDPCALYASE Sbjct: 33 ARECVGKTVTLQGNLDPCALYASE 56
>gi|6320252|ref|NP_010332.1| fifth enzyme in the heme biosynthetic pathway; Hem12p [Saccharomyces cerevisiae] gi|416894|sp|P32347|DCUP_YEAST Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|283290|pir||S23471 uroporphyrinogen decarboxylase (EC 4.1.1.37) - yeast (Saccharomyces cerevisiae) gi|3767|emb|CAA45253.1| uroporphyrinogen decarboxylase [Saccharomyces cerevisiae] gi|4776|emb|CAA79514.1| uroporphyrinogen decarboxylase [Saccharomyces cerevisiae] gi|798900|emb|CAA89078.1| Hem12p [Saccharomyces cerevisiae] Length = 362 Score = 109 bits (273), Expect = 4e-22 Identities = 66/162 (40%), Positives = 85/162 (52%), Gaps = 1/162 (0%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEV-VASELGYVFQAITLTRQRLAGRVP 2607 QA+GM V M+ GKGP FPEPLR +DL+ + D +V V EL + F+AIT+TR +L G VP Sbjct: 87 QAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVP 146 Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787 L GF G P W + M YM EGGGS Sbjct: 147 LFGFCGGP---------------WTL------------------------MVYMTEGGGS 167 Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 AK+W+ P+ SH+LL+ +TD V +L QVVAGAQ+ Sbjct: 168 RLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQI 209
Score = 51.2 bits (121), Expect = 2e-04 Identities = 36/132 (27%), Positives = 57/132 (43%), Gaps = 1/132 (0%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP-VPMVRIGMG*VKVVLWS 3458 LQ+FES G L F++F+LPY+R +A++V RL+E G+ +PM Sbjct: 210 LQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPM-------------- 255 Query: 3459 FQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEV 3638 I+FAK +AL++L +G++V Sbjct: 256 ---------------------------------------IVFAKGSWYALDKLCCSGFDV 276 Query: 3639 VGLDWTVAPKKA 3674 V LDW+ P++A Sbjct: 277 VSLDWSWDPREA 288
Score = 48.5 bits (114), Expect = 0.001 Identities = 22/34 (64%), Positives = 24/34 (70%) Frame = +3 Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 FP KND LRAA GE+ + P W MRQAGRYLP Sbjct: 4 FPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLP 37
Score = 44.3 bits (103), Expect = 0.021 Identities = 21/48 (43%), Positives = 31/48 (64%), Gaps = 2/48 (4%) Frame = +3 Query: 4176 QEEIGQLVKQMLDDFG--PHRYIANLGHGLYPDMDPEHVGAFVDAVHK 4313 +E I + VKQM++ FG RYI N GHG +P MDP+ + F++ H+ Sbjct: 311 KEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHR 358
Score = 37.7 bits (86), Expect(2) = 2e-04 Identities = 18/25 (72%), Positives = 23/25 (92%), Gaps = 2/25 (8%) Frame = +2 Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194 +QP+RR+ L+DAAIIFSDILV+PQ Sbjct: 63 IQPVRRYRGLIDAAIIFSDILVIPQ 87
Score = 32.3 bits (72), Expect(2) = 2e-04 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Frame = +1 Query: 1900 GEKFSRGRGGLWR-ASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQVRGPQKR 2076 GEK R + R A R P E+ E + +DFF TCR E E+T+Q P +R Sbjct: 18 GEKVERPPCWIMRQAGRYLP------EYHEVKNNRDFFQTCRDAEIASEITIQ---PVRR 68 Query: 2077 ER 2082 R Sbjct: 69 YR 70
>gi|31240435|ref|XP_320631.1| ENSANGP00000021292 [Anopheles gambiae] gi|30174144|gb|EAA00166.2| ENSANGP00000021292 [Anopheles gambiae str. PEST] Length = 351 Score = 109 bits (272), Expect = 5e-22 Identities = 69/161 (42%), Positives = 84/161 (52%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALG+ V M PG GP PEPL DL+RL + L YV +AIT+ R+ L G+VPL Sbjct: 83 QALGITVEMKPGVGPVLPEPLVGPADLDRLNQTGTI-ERLKYVGEAITMMRRMLEGKVPL 141 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 GF GAP W + G YM+EGGGS Sbjct: 142 FGFTGAP---------------WTLMG------------------------YMIEGGGSK 162 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 TM++AK WL P+AS +LL ILTD +V YLV QV AGAQ+ Sbjct: 163 TMSKAKGWLADHPEASQKLLDILTDQVVDYLVMQVKAGAQM 203
Score = 54.7 bits (130), Expect(3) = 1e-18 Identities = 25/34 (73%), Positives = 25/34 (73%) Frame = +3 Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 FP LKND LRAA GE D PVW MRQAGRYLP Sbjct: 2 FPPLKNDNLLRAARGEPVDRVPVWVMRQAGRYLP 35
Score = 54.3 bits (129), Expect(2) = 3e-08 Identities = 36/132 (27%), Positives = 54/132 (40%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461 LQ+FES A HL + F +LP ++ + + +L + G+ VPM Sbjct: 204 LQVFESSADHLSKEQFLSVSLPCLKRIRVDLLRKLADEGVPAVPM--------------- 248 Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641 ++FAK +LEE+AQ GYEV+ Sbjct: 249 --------------------------------------VLFAKGAMHSLEEMAQTGYEVL 270 Query: 3642 GLDWTVAPKKAR 3677 GLDWT+ P++AR Sbjct: 271 GLDWTIDPEEAR 282
Score = 51.6 bits (122), Expect = 1e-04 Identities = 24/46 (52%), Positives = 29/46 (63%) Frame = +3 Query: 4173 PQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVH 4310 P EE+ +LV M+ FG HRYIANLGHG+ P E + V AVH Sbjct: 303 PPEELRELVLTMVRKFGKHRYIANLGHGITPQTPIESMSVLVQAVH 348
Score = 42.0 bits (97), Expect(3) = 1e-18 Identities = 16/27 (59%), Positives = 21/27 (77%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EF+E RA DFF+ CR+PE CE+T+Q Sbjct: 36 EFQEVRAKHDFFTVCRTPELACEVTMQ 62
Score = 41.6 bits (96), Expect(3) = 1e-18 Identities = 19/23 (82%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 +QPLRRF LDA+IIFSDILV+PQ Sbjct: 61 MQPLRRFDLDASIIFSDILVIPQ 83
Score = 29.3 bits (64), Expect(2) = 3e-08 Identities = 13/21 (61%), Positives = 16/21 (76%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALY 3837 +R+ VG VTLQGNLDP +Y Sbjct: 281 ARKRVGPNVTLQGNLDPQDMY 301
>gi|19921920|ref|NP_610501.1| CG1818-PA [Drosophila melanogaster] gi|8928075|sp|Q9V595|DCUP_DROME Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|7303877|gb|AAF58922.1| CG1818-PA [Drosophila melanogaster] Length = 356 Score = 107 bits (267), Expect = 2e-21 Identities = 67/161 (41%), Positives = 84/161 (52%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALG+ V M G GP P+P+ +DL+RL P+ S L YV AIT+ R +L GRVPL Sbjct: 88 QALGLTVEMHAGVGPVLPQPIVVPEDLKRLT-PDGALSRLSYVGDAITMMRHKLEGRVPL 146 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGF GAP W + G YM+EGGGS Sbjct: 147 IGFTGAP---------------WTLMG------------------------YMIEGGGSK 167 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 TM++AK WL + P+ S L +LTDA+V YL QV AGAQ+ Sbjct: 168 TMSKAKAWLNEHPEDSKLFLNLLTDAIVDYLEMQVKAGAQM 208
Score = 53.9 bits (128), Expect(3) = 1e-17 Identities = 25/34 (73%), Positives = 25/34 (73%) Frame = +3 Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 FP LKND LRAA GE D PVW MRQAGRYLP Sbjct: 7 FPVLKNDNLLRAARGEVVDRVPVWVMRQAGRYLP 40
Score = 48.1 bits (113), Expect(2) = 2e-06 Identities = 33/132 (25%), Positives = 53/132 (40%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461 LQ+FES A HL + F ++ +PY++ + ++ RL + + VPM Sbjct: 209 LQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKAIPVVPMT-------------- 254 Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641 +FAK +L+E ++ GY+V+ Sbjct: 255 ---------------------------------------LFAKGAGHSLKEQSELGYDVI 275 Query: 3642 GLDWTVAPKKAR 3677 GLDWTV P +AR Sbjct: 276 GLDWTVDPLEAR 287
Score = 43.9 bits (102), Expect = 0.027 Identities = 20/45 (44%), Positives = 27/45 (60%) Frame = +3 Query: 4179 EEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHK 4313 +E+ L +M+ FG RYIANLGHG+ P + V+AVHK Sbjct: 310 DELRNLTTEMVHKFGKSRYIANLGHGITPQTPITSMEVLVEAVHK 354
Score = 41.6 bits (96), Expect(3) = 1e-17 Identities = 19/23 (82%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 +QPLRRF LDA+IIFSDILV+PQ Sbjct: 66 MQPLRRFDLDASIIFSDILVIPQ 88
Score = 39.3 bits (90), Expect(3) = 1e-17 Identities = 15/27 (55%), Positives = 20/27 (74%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 EF+E R DFF+ CR+PE CE+T+Q Sbjct: 41 EFQELRKHHDFFTVCRTPELACEVTMQ 67
Score = 29.3 bits (64), Expect(2) = 2e-06 Identities = 12/21 (57%), Positives = 15/21 (71%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALY 3837 +R VG +TLQGNLDP +Y Sbjct: 286 ARNLVGPNITLQGNLDPQDMY 306
>gi|21430840|gb|AAM51098.1| SD19419p [Drosophila melanogaster] Length = 356 Score = 107 bits (267), Expect = 2e-21 Identities = 67/161 (41%), Positives = 84/161 (52%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALG+ V M G GP P+P+ +DL+RL P+ S L YV AIT+ R +L GRVPL Sbjct: 88 QALGLTVEMHAGVGPVLPQPIVVPEDLKRLT-PDGALSRLSYVGDAITMMRHKLEGRVPL 146 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGF GAP W + G YM+EGGGS Sbjct: 147 IGFTGAP---------------WTLMG------------------------YMIEGGGSK 167 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 TM++AK WL + P+ S L +LTDA+V YL QV AGAQ+ Sbjct: 168 TMSKAKAWLNEHPEDSKLFLNLLTDAIVDYLEMQVKAGAQM 208
Score = 46.6 bits (109), Expect(2) = 5e-06 Identities = 32/132 (24%), Positives = 53/132 (40%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461 LQ+FES A HL + F ++ +PY++ + ++ RL + + VP+ Sbjct: 209 LQVFESSAEHLSKEQFLQWCVPYLKRIRDELVDRLTKKAIPVVPIT-------------- 254 Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641 +FAK +L+E ++ GY+V+ Sbjct: 255 ---------------------------------------LFAKGAGHSLKEQSELGYDVI 275 Query: 3642 GLDWTVAPKKAR 3677 GLDWTV P +AR Sbjct: 276 GLDWTVDPLEAR 287
Score = 29.3 bits (64), Expect(2) = 5e-06 Identities = 12/21 (57%), Positives = 15/21 (71%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALY 3837 +R VG +TLQGNLDP +Y Sbjct: 286 ARNLVGPNITLQGNLDPQDMY 306
>gi|4140695|gb|AAD04167.1| uroporphyrinogen decarboxylase [Homo sapiens] Length = 100 Score = 104 bits (259), Expect = 2e-20 Identities = 51/51 (100%), Positives = 51/51 (100%) Frame = +1 Query: 2758 MTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 MTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ Sbjct: 4 MTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 54
Score = 95.1 bits (235), Expect = 1e-17 Identities = 46/46 (100%), Positives = 46/46 (100%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 3416 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM Sbjct: 55 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPM 100
>gi|3915203|sp|O18601|DCUP_DROVI Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|2317917|gb|AAB66372.1| uroprophyrinogen decarboxylase [Drosophila virilis] Length = 386 Score = 103 bits (256), Expect = 4e-20 Identities = 65/161 (40%), Positives = 83/161 (51%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 QALG+ V M G GP P+P+ +DL+RL P+ S L YV AIT+ R +L GRVPL Sbjct: 99 QALGLTVEMHAGVGPVLPQPICTPEDLKRLT-PDGALSRLTYVGDAITMMRHKLDGRVPL 157 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGF GAP W + G YM+EGGGS Sbjct: 158 IGFTGAP---------------WTLMG------------------------YMIEGGGSK 178 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 TM++AK WL P+ + L +LTD +V YL QV+AGAQ+ Sbjct: 179 TMSKAKAWLTNYPEDTKLFLILLTDVIVDYLEMQVIAGAQM 219
Score = 56.2 bits (134), Expect(2) = 1e-12 Identities = 26/36 (72%), Positives = 26/36 (72%) Frame = +3 Query: 1752 QGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 Q FP LKND LRAA GE D PVW MRQAGRYLP Sbjct: 16 QAFPPLKNDNLLRAARGEVVDRVPVWVMRQAGRYLP 51
Score = 48.9 bits (115), Expect(2) = 6e-07 Identities = 40/132 (30%), Positives = 58/132 (43%) Frame = +3 Query: 3282 LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG*VKVVLWSF 3461 LQ+FES A HL + F + PY+R + + RL + + VP+V + +L Sbjct: 220 LQVFESSAEHLSKEEFLLGSEPYLRRIRDDLVDRLTKKVIPAVPLVSSYPNNIFTLL--- 276 Query: 3462 QAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFAKDGHFALEELAQAGYEVV 3641 L SL IIFAK +L+E ++ GY+V+ Sbjct: 277 --------------------------TYLISLL-----IIFAKGAGHSLKEQSELGYDVI 305 Query: 3642 GLDWTVAPKKAR 3677 GLDWTV P +AR Sbjct: 306 GLDWTVDPVEAR 317
Score = 42.0 bits (97), Expect(2) = 1e-12 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 3/76 (3%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQVRGPQKRERFMPSVCHLATCLLFPTA---TASL 2145 EF+E R DFF+ CR+PE CE+T+Q P +R S+ + L+ P A T + Sbjct: 52 EFQELRKQHDFFTVCRTPELACEVTMQ---PLRRFDLDASII-FSDILVIPQALGLTVEM 107 Query: 2146 PSGCCHHFLRHPCCTP 2193 +G L P CTP Sbjct: 108 HAG-VGPVLPQPICTP 122
Score = 41.6 bits (96), Expect = 0.13 Identities = 19/23 (82%), Positives = 22/23 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQ 2194 +QPLRRF LDA+IIFSDILV+PQ Sbjct: 77 MQPLRRFDLDASIIFSDILVIPQ 99
Score = 35.4 bits (80), Expect = 9.7 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = +3 Query: 4182 EIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVH 4310 E+ L +M+ G RYIAN+GHG+ P + V+A H Sbjct: 341 ELRSLATEMVHKCGKSRYIANVGHGITPQTPITSMEVLVEAAH 383
Score = 30.0 bits (66), Expect(2) = 6e-07 Identities = 12/21 (57%), Positives = 16/21 (76%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALY 3837 +R VG +TLQGNLDP ++Y Sbjct: 316 ARAVVGPNITLQGNLDPQSMY 336
>gi|32418962|ref|XP_329959.1| hypothetical protein [Neurospora crassa] gi|28926041|gb|EAA35030.1| hypothetical protein [Neurospora crassa] Length = 390 Score = 101 bits (252), Expect = 1e-19 Identities = 63/164 (38%), Positives = 83/164 (50%), Gaps = 3/164 (1%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQD---LERLRDPEVVASELGYVFQAITLTRQRLAGR 2601 QA+GM V MV KGP FP PLR D E ++ VA EL YV++AITLTR++L GR Sbjct: 109 QAMGMTVEMVDKKGPHFPNPLRSPSDGQYAELMKRDVDVAKELDYVYKAITLTRKKLDGR 168 Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781 VPL GF GAP W + + YMVEGG Sbjct: 169 VPLFGFTGAP---------------WTL------------------------LCYMVEGG 189 Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 G+ + K W+Y+ P+ + LL+ +++ V YL QV AGAQ+ Sbjct: 190 GTKLFKEVKTWIYKYPEETKALLQKISELCVEYLALQVKAGAQI 233
Score = 57.4 bits (137), Expect(2) = 3e-07 Identities = 43/149 (28%), Positives = 56/149 (37%), Gaps = 2/149 (1%) Frame = +3 Query: 3234 SSLCVTYFSSPYPN*A--LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP 3407 S LCV Y + A +Q+F+S AG L P F F+ PY+ +AK + RL+E GL P Sbjct: 216 SELCVEYLALQVKAGAQIVQVFDSWAGELSPSSFKTFSQPYLTYIAKHLPLRLKEMGLEP 275 Query: 3408 VPMVRIGMG*VKVVLWSFQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFA 3587 VPMV +F Sbjct: 276 VPMV-----------------------------------------------------VFP 282 Query: 3588 KDGHFALEELAQAGYEVVGLDWTVAPKKA 3674 K +AL+ GY VVGLDW P +A Sbjct: 283 KGAWYALDAACDMGYNVVGLDWLHDPAEA 311
Score = 37.4 bits (85), Expect(3) = 9e-07 Identities = 19/30 (63%), Positives = 23/30 (76%), Gaps = 2/30 (6%) Frame = +2 Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQVPTQT 2209 LQP+ R+ L+DAAIIFSDILV+PQ T Sbjct: 85 LQPIERYAGLIDAAIIFSDILVIPQAMGMT 114
Score = 35.8 bits (81), Expect = 7.4 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 4/63 (6%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDF---GPHR-YIANLGHGLYPDMDPEHVGAFVDA 4304 L G L E I ++V++M+ F G H+ +I NLGHG+ P ++P+ + F + Sbjct: 322 LQGNADPGVLYGSHEAITKVVEEMVQGFDWHGRHKGWIVNLGHGITPFVNPDDLKFFFEE 381 Query: 4305 VHK 4313 +H+ Sbjct: 382 IHR 384
Score = 33.9 bits (76), Expect(3) = 9e-07 Identities = 13/27 (48%), Positives = 17/27 (62%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 E+ E + +DFF CR+PE LTLQ Sbjct: 60 EYHEAKGGRDFFEVCRNPEIASTLTLQ 86
Score = 26.2 bits (56), Expect(3) = 9e-07 Identities = 16/34 (47%), Positives = 17/34 (50%) Frame = +3 Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 FP LKND LRAA + AGRYLP Sbjct: 34 FPPLKNDLLLRAARAP--------LILTAGRYLP 59
Score = 22.7 bits (47), Expect(2) = 3e-07 Identities = 9/17 (52%), Positives = 11/17 (64%) Frame = +1 Query: 3793 KTVTLQGNLDPCALYAS 3843 + + LQGN DP LY S Sbjct: 318 RPMVLQGNADPGVLYGS 334
>gi|38110215|gb|EAA55971.1| hypothetical protein MG01622.4 [Magnaporthe grisea 70-15] Length = 367 Score = 101 bits (251), Expect = 1e-19 Identities = 63/164 (38%), Positives = 85/164 (51%), Gaps = 3/164 (1%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQD---LERLRDPEVVASELGYVFQAITLTRQRLAGR 2601 QA+GM V MV KGP FP PL+ D E L V+ EL YV++AITLTR++L GR Sbjct: 88 QAMGMVVEMVDKKGPHFPNPLQSPDDGQYAEVLARDVDVSKELDYVYKAITLTRKKLQGR 147 Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781 VPLIGF GAP W ++ YMVEGG Sbjct: 148 VPLIGFCGAP---------------WTLF------------------------CYMVEGG 168 Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQV 2913 G+ Q+K+W+++ P+ S ++L+ + + V YL QV AGAQ+ Sbjct: 169 GTKLFIQSKKWIFRHPEESKKMLQKIAELCVEYLALQVQAGAQL 212
Score = 60.1 bits (144), Expect(2) = 5e-08 Identities = 42/149 (28%), Positives = 59/149 (39%), Gaps = 2/149 (1%) Frame = +3 Query: 3234 SSLCVTYFSSPYPN*A--LQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAP 3407 + LCV Y + A +Q+F+S AG L P F +F+ PY+R +++ + RL+E L P Sbjct: 195 AELCVEYLALQVQAGAQLVQVFDSWAGELSPASFEQFSAPYLRYISENLPKRLKELSLDP 254 Query: 3408 VPMVRIGMG*VKVVLWSFQAKSCMDWSDHWRAAEVQSRKISGCSKALCSLRSAFF*IIFA 3587 VPM+ +F Sbjct: 255 VPMI-----------------------------------------------------VFP 261 Query: 3588 KDGHFALEELAQAGYEVVGLDWTVAPKKA 3674 K FALE+ GY VVGLDW +P KA Sbjct: 262 KGAWFALEDCCAMGYNVVGLDWLYSPAKA 290
Score = 51.2 bits (121), Expect(3) = 2e-13 Identities = 20/34 (58%), Positives = 25/34 (73%) Frame = +3 Query: 1758 FPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 F LKND +R AWG++ + P+W MRQAGRYLP Sbjct: 5 FEPLKNDLVIRTAWGQKVERPPIWIMRQAGRYLP 38
Score = 37.0 bits (84), Expect(3) = 2e-13 Identities = 19/25 (76%), Positives = 22/25 (88%), Gaps = 2/25 (8%) Frame = +2 Query: 2126 LQPLRRF--LLDAAIIFSDILVVPQ 2194 LQP+ RF LLDA+IIFSDILV+PQ Sbjct: 64 LQPIDRFDGLLDASIIFSDILVIPQ 88
Score = 32.7 bits (73), Expect(3) = 2e-13 Identities = 13/27 (48%), Positives = 16/27 (59%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 E+ E + +DFF CR PE LTLQ Sbjct: 39 EYHEAKGNRDFFECCRDPEVASTLTLQ 65
Score = 22.7 bits (47), Expect(2) = 5e-08 Identities = 8/18 (44%), Positives = 12/18 (66%) Frame = +1 Query: 3793 KTVTLQGNLDPCALYASE 3846 + + LQGN DP LY ++ Sbjct: 297 REIVLQGNADPGVLYGTK 314
>gi|21674849|ref|NP_662914.1| uroporphyrinogen decarboxylase [Chlorobium tepidum TLS] gi|29611777|sp|Q8KAW2|DCUP_CHLTE Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|21648071|gb|AAM73256.1| uroporphyrinogen decarboxylase [Chlorobium tepidum TLS] Length = 351 Score = 90.5 bits (223), Expect = 3e-16 Identities = 55/159 (34%), Positives = 81/159 (50%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 +A+GM V ++ KG P+R + D+++L DP++ +LGYV AI L ++ L RVPL Sbjct: 80 EAMGMNVEIIETKGIKLTPPIRSQADIDKLIDPDI-DEKLGYVLDAIRLAKKELNDRVPL 138 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGF+GA W ++ TY VEGGGS Sbjct: 139 IGFSGA---------------AWTLF------------------------TYAVEGGGSK 159 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907 AK+ +Y+ P+ +HQLL+ ++D + YLV QV AGA Sbjct: 160 NYTWAKKMMYREPKMAHQLLQKISDCISAYLVKQVEAGA 198
Score = 45.8 bits (107), Expect(3) = 8e-10 Identities = 20/31 (64%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND F+RA + T TP+W MRQAGRYLP Sbjct: 2 LKNDLFIRALKRQATPRTPIWVMRQAGRYLP 32
Score = 37.4 bits (85), Expect = 2.5 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 4/51 (7%) Frame = +3 Query: 4179 EEIGQLVKQMLDDFGPHR----YIANLGHGLYPDMDPEHVGAFVDAVHKHS 4319 E+I ++L FG H ++ NLGHG+ PD+DP ++ V+ V + S Sbjct: 297 EKIKSEAAKVLKQFGQHNDHSGHVFNLGHGILPDVDPANLKCLVEFVKEES 347
Score = 33.9 bits (76), Expect(3) = 8e-10 Identities = 12/27 (44%), Positives = 18/27 (66%) Frame = +1 Query: 1975 EFRETRAAQDFFSTCRSPEACCELTLQ 2055 E+R R DF + C++PE CE+T+Q Sbjct: 33 EYRAVREKTDFLTLCKTPELACEVTIQ 59
Score = 32.3 bits (72), Expect(2) = 1.4 Identities = 15/34 (44%), Positives = 20/34 (58%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I FAKD + L ++A G + VGL W + KAR Sbjct: 241 IAFAKDMNTILSDIADCGADAVGLGWNIDIAKAR 274
Score = 28.5 bits (62), Expect(3) = 8e-10 Identities = 14/21 (66%), Positives = 17/21 (80%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVV 2188 +QP+ +DAAIIFSDILVV Sbjct: 58 IQPVDLMGVDAAIIFSDILVV 78
Score = 24.6 bits (52), Expect(2) = 1.4 Identities = 10/23 (43%), Positives = 15/23 (65%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYAS 3843 +R+ + V LQGN+DP LY + Sbjct: 273 ARKELNDRVCLQGNMDPTVLYGT 295
>gi|21232275|ref|NP_638192.1| uroporphyrinogen decarboxylase [Xanthomonas campestris pv. campestris str. ATCC 33913] gi|23813977|sp|Q8P6X1|DCUP_XANCP Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|21114039|gb|AAM42116.1| uroporphyrinogen decarboxylase [Xanthomonas campestris pv. campestris str. ATCC 33913] Length = 354 Score = 88.2 bits (217), Expect = 1e-15 Identities = 56/159 (35%), Positives = 76/159 (47%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+E+ V G+GP F P+R+ + RL P++ +EL YV A+ L R+ L G VPLI Sbjct: 82 AMGLELYFVEGEGPKFRHPVRDADAIHRLGVPDM-ETELRYVMDAVRLIRRELDGAVPLI 140 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A YM+EGGGS Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 A+ K + PQ H LL +TDA++ YL Q AGAQ Sbjct: 162 YARIKAMAFNAPQLLHHLLSTVTDAVIAYLSAQRAAGAQ 200
Score = 45.4 bits (106), Expect(3) = 1e-10 Identities = 21/31 (67%), Positives = 22/31 (70%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND LRA + D TPVW MRQAGRYLP Sbjct: 2 LKNDRLLRALRRQPVDRTPVWLMRQAGRYLP 32
Score = 41.6 bits (96), Expect = 0.13 Identities = 20/51 (39%), Positives = 31/51 (60%), Gaps = 2/51 (3%) Frame = +3 Query: 4176 QEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322 + E+G+ + G R ++ NLGHG+ PDM+P+HVG V+AV S+ Sbjct: 303 RSEVGKTLDSYAYGNGGSREGHVFNLGHGMSPDMNPDHVGVLVEAVQTLSK 353
Score = 38.5 bits (88), Expect = 1.1 Identities = 18/52 (34%), Positives = 33/52 (63%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434 ALQ+F++ G L P ++ +F+LPY+ +A++++ R +G P+V G G Sbjct: 201 ALQVFDTWGGVLSPAMYREFSLPYLTRIAQELE---RGSGEERTPLVLFGKG 249
Score = 37.7 bits (86), Expect(3) = 1e-10 Identities = 17/22 (77%), Positives = 19/22 (86%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL RF LDAAI+FSDIL +P Sbjct: 59 LQPLERFPLDAAILFSDILTIP 80
Score = 31.2 bits (69), Expect(2) = 0.19 Identities = 12/29 (41%), Positives = 19/29 (65%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVA 3662 ++F K + ELA +G E VG+DWT++ Sbjct: 244 VLFGKGNGAYVSELAASGAEAVGVDWTIS 272
Score = 28.9 bits (63), Expect(2) = 0.19 Identities = 14/27 (51%), Positives = 15/27 (55%) Frame = +1 Query: 3781 ECVGKTVTLQGNLDPCALYASEVTARA 3861 E G V LQGNLDP LY S R+ Sbjct: 278 ERAGGRVALQGNLDPATLYGSPDAIRS 304
Score = 28.1 bits (61), Expect(3) = 1e-10 Identities = 13/28 (46%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A F ++P+ CE+TLQ Sbjct: 33 EYRATRARAGSFLGMAKNPDIACEVTLQ 60
>gi|21243740|ref|NP_643322.1| uroporphyrinogen decarboxylase [Xanthomonas axonopodis pv. citri str. 306] gi|23813978|sp|Q8PI85|DCUP_XANAC Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|21109326|gb|AAM37858.1| uroporphyrinogen decarboxylase [Xanthomonas axonopodis pv. citri str. 306] Length = 354 Score = 86.7 bits (213), Expect = 4e-15 Identities = 54/159 (33%), Positives = 76/159 (47%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+E+ V G+GP F P+R+ + RL P++ +EL YV A+ + R+ L G VPLI Sbjct: 82 AMGLELYFVEGEGPKFRHPVRDAAAIHRLGVPDM-ETELRYVMDAVRVIRRELDGSVPLI 140 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A YM+EGGGS Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 A+ K + P+ H LL +TDA++ YL Q AGAQ Sbjct: 162 YARIKAMAFNAPELLHHLLNTVTDAVIAYLAAQRAAGAQ 200
Score = 45.1 bits (105), Expect(3) = 1e-10 Identities = 21/31 (67%), Positives = 22/31 (70%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND LRA + D TPVW MRQAGRYLP Sbjct: 2 LKNDRLLRALNRQPVDRTPVWLMRQAGRYLP 32
Score = 43.5 bits (101), Expect = 0.035 Identities = 21/49 (42%), Positives = 30/49 (61%), Gaps = 2/49 (4%) Frame = +3 Query: 4182 EIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322 E+G+ + G R ++ NLGHG+ PDM+PEHVG V+AV S+ Sbjct: 305 EVGKTLDSYAQGNGGSREGHVFNLGHGMSPDMNPEHVGVLVEAVQTLSK 353
Score = 38.5 bits (88), Expect = 1.1 Identities = 18/52 (34%), Positives = 32/52 (61%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434 ALQ+F++ G L P ++ +F+LPY+ +A++++ R G P+V G G Sbjct: 201 ALQVFDTWGGVLSPAMYREFSLPYLTRIARELE---RGDGAERTPLVLFGKG 249
Score = 38.1 bits (87), Expect(3) = 1e-10 Identities = 17/22 (77%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL+RF LDAAI+FSDIL +P Sbjct: 59 LQPLQRFPLDAAILFSDILTIP 80
>gi|28872231|ref|NP_794850.1| uroporphyrinogen decarboxylase [Pseudomonas syringae pv. tomato str. DC3000] gi|38257459|sp|Q87V23|DCUP_PSESM Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|28855485|gb|AAO58545.1| uroporphyrinogen decarboxylase [Pseudomonas syringae pv. tomato str. DC3000] Length = 354 Score = 85.1 bits (209), Expect = 1e-14 Identities = 56/159 (35%), Positives = 75/159 (47%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI Sbjct: 84 AMGLGLYFETGEGPRFKKTVSTLADIEALPIPDA-QQDLGYVMDAVSTIRRELNGRVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GFAG+P W A TYMVEGG S Sbjct: 143 GFAGSP--WTLA-------------------------------------TYMVEGGSSKD 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 ++K LY PQA H LL L ++ YL GQ++AGAQ Sbjct: 164 FRKSKAMLYDNPQAMHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 48.5 bits (114), Expect(3) = 1e-12 Identities = 22/31 (70%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND FLRA + D TPVW MRQAGRYLP Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 45.1 bits (105), Expect = 0.012 Identities = 25/67 (37%), Positives = 38/67 (56%), Gaps = 1/67 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G + L E I Q V ++L +G ++ NLGHG+ P++DP + GAF++AVH+ Sbjct: 288 LQGNMDPTVLYARPEAIRQEVARILASYGSGTGHVFNLGHGITPEVDPANAGAFINAVHE 347 Query: 4314 HSRLLRQ 4334 S Q Sbjct: 348 LSAQYHQ 354
Score = 37.7 bits (86), Expect = 1.9 Identities = 30/105 (28%), Positives = 42/105 (40%) Frame = +1 Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873 + L L W C +GE +R+ VG V+LQGN+DP LYA R + Sbjct: 265 DTLGLDWTCDIGE--------------ARQRVGNKVSLQGNMDPTVLYARPEAIRQEVAR 310 Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008 +L G VFN+ + + P G F+ VH Sbjct: 311 ILASYGSGTG------HVFNLGHGITPE---VDPANAGAFINAVH 346
Score = 35.8 bits (81), Expect(3) = 1e-12 Identities = 16/22 (72%), Positives = 19/22 (86%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL R+ LDAAI+FSDIL +P Sbjct: 61 LQPLDRYPLDAAILFSDILTIP 82
Score = 33.5 bits (75), Expect(3) = 1e-12 Identities = 15/28 (53%), Positives = 21/28 (75%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R +RA A DF S C++P+ CE+TLQ Sbjct: 35 EYRASRASAGDFMSLCKNPQFACEVTLQ 62
>gi|16123871|ref|NP_407184.1| uroporphyrinogen decarboxylase [Yersinia pestis] gi|22124411|ref|NP_667834.1| uroporphyrinogen decarboxylase [Yersinia pestis KIM] gi|23813999|sp|Q8ZAQ7|DCUP_YERPE Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|25291020|pir||AF0454 uroporphyrinogen decarboxylase (EC 4.1.1.37) [imported] - Yersinia pestis (strain CO92) gi|15981650|emb|CAC93202.1| uroporphyrinogen decarboxylase [Yersinia pestis CO92] gi|21957194|gb|AAM84085.1| uroporphyrinogen decarboxylase [Yersinia pestis KIM] Length = 355 Score = 84.7 bits (208), Expect = 1e-14 Identities = 55/159 (34%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ D+E+L P+ ELGYV A+ R+ LAG VPLI Sbjct: 84 AMGLGLYFETGEGPRFQSPITCRADVEKLPIPDP-EQELGYVMNAVRTIRRELAGSVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ +Y PQ H LL L D+++ YL Q+ AGAQ Sbjct: 164 FTKLKKMMYAEPQTLHLLLDKLADSVILYLNAQIKAGAQ 202
Score = 50.4 bits (119), Expect = 3e-04 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G S L P I Q V +L FG ++ NLGHG++ D+ P H GAFV+AVH Sbjct: 288 LQGNMDPSVLYAPPARIEQEVSTILASFGQGEGHVFNLGHGIHQDVPPAHAGAFVNAVHA 347 Query: 4314 HSRLLRQ 4334 SR Q Sbjct: 348 LSRPYHQ 354
Score = 49.3 bits (116), Expect(3) = 8e-13 Identities = 22/32 (68%), Positives = 24/32 (75%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA + D TPVW MRQAGRYLP Sbjct: 3 ELKNDRYLRALLRQPVDMTPVWMMRQAGRYLP 34
Score = 37.7 bits (86), Expect(3) = 8e-13 Identities = 16/22 (72%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 +QPLRR+ LDAAI+FSDIL +P Sbjct: 61 MQPLRRYPLDAAILFSDILTIP 82
Score = 31.6 bits (70), Expect(3) = 8e-13 Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E++ TRA A DF S C++ E CE+T+Q Sbjct: 35 EYKATRAIAGDFMSLCKNAELACEVTMQ 62
Score = 31.2 bits (69), Expect(2) = 0.19 Identities = 26/78 (33%), Positives = 31/78 (39%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954 +R VG V LQGN+DP LYA + +L G VFN L Sbjct: 278 ARRRVGDKVALQGNMDPSVLYAPPARIEQEVSTILASFGQGEG------HVFN--LGHGI 329 Query: 3955 HLYTISPRKTGLFVAVVH 4008 H + P G FV VH Sbjct: 330 H-QDVPPAHAGAFVNAVH 346
Score = 28.9 bits (63), Expect(2) = 0.19 Identities = 14/33 (42%), Positives = 18/33 (54%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 +F K G LE +A G + +GLDWT AR Sbjct: 247 LFTKGGGPWLEAMAATGCDALGLDWTTDIADAR 279
>gi|33598623|ref|NP_886266.1| uroporphyrinogen decarboxylase [Bordetella parapertussis] gi|33574752|emb|CAE39411.1| uroporphyrinogen decarboxylase [Bordetella parapertussis] Length = 358 Score = 84.3 bits (207), Expect = 2e-14 Identities = 55/159 (34%), Positives = 73/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GFAG+P W + YMVEG GS Sbjct: 144 GFAGSP---------------WTI------------------------ACYMVEGRGSDD 164 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K LY RP H++L I +A YL Q+ AGAQ Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 50.1 bits (118), Expect(3) = 6e-11 Identities = 22/31 (70%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND FLRA E YTP+W MRQAGRYLP Sbjct: 6 LKNDVFLRALLREPVPYTPIWLMRQAGRYLP 36
Score = 37.0 bits (84), Expect = 3.3 Identities = 20/46 (43%), Positives = 26/46 (56%), Gaps = 3/46 (6%) Frame = +3 Query: 4200 KQMLDDFGP---HRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLL 4328 ++ LD FGP ++ NLGHG+ PE V VD VH +SR L Sbjct: 310 RRTLDAFGPVGKGGHVFNLGHGISQYSPPEVVSELVDEVHTYSRAL 355
Score = 36.6 bits (83), Expect(3) = 6e-11 Identities = 17/22 (77%), Positives = 19/22 (86%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL R+ LDAAI+FSDIL VP Sbjct: 63 LQPLARYPLDAAILFSDILTVP 84
Score = 36.2 bits (82), Expect = 5.7 Identities = 18/34 (52%), Positives = 22/34 (64%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I+F+K G LEE+A G + VGLDWTV AR Sbjct: 247 IVFSKGGGQWLEEIAACGCDAVGLDWTVNLGTAR 280
Score = 25.4 bits (54), Expect(3) = 6e-11 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+ TRA A F ++P+ CE+TLQ Sbjct: 37 EYNATRARAGSFMGLAQNPDYACEVTLQ 64
>gi|33603574|ref|NP_891134.1| uroporphyrinogen decarboxylase [Bordetella bronchiseptica] gi|33577699|emb|CAE34964.1| uroporphyrinogen decarboxylase [Bordetella bronchiseptica] Length = 358 Score = 84.3 bits (207), Expect = 2e-14 Identities = 55/159 (34%), Positives = 73/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GFAG+P W + YMVEG GS Sbjct: 144 GFAGSP---------------WTI------------------------ACYMVEGRGSDD 164 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K LY RP H++L I +A YL Q+ AGAQ Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 35.8 bits (81), Expect = 7.4 Identities = 18/34 (52%), Positives = 21/34 (61%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I+F K G LEE+A G + VGLDWTV AR Sbjct: 247 IVFTKGGGQWLEEIAACGCDAVGLDWTVNLGTAR 280
>gi|23469744|ref|ZP_00125078.1| COG0407: Uroporphyrinogen-III decarboxylase [Pseudomonas syringae pv. syringae B728a] Length = 354 Score = 84.0 bits (206), Expect = 2e-14 Identities = 56/159 (35%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI Sbjct: 84 AMGQGLYFETGEGPRFRKTVSTLADIEALPIPDA-QQDLGYVMDAVSTIRRELNGRVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GFAG+P W A TYMVEGG S Sbjct: 143 GFAGSP--WTLA-------------------------------------TYMVEGGSSKD 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 ++K LY PQA H LL L ++ YL GQ++AGAQ Sbjct: 164 FRKSKAMLYDNPQAMHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 44.7 bits (104), Expect = 0.016 Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 1/62 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G + L E I Q V ++L +G ++ NLGHG+ P++DP + GAF++AVH+ Sbjct: 288 LQGNMDPTVLYARPEAIRQEVARILASYGSGTGHVFNLGHGITPEVDPANAGAFINAVHE 347 Query: 4314 HS 4319 S Sbjct: 348 LS 349
Score = 37.7 bits (86), Expect = 1.9 Identities = 30/105 (28%), Positives = 42/105 (40%) Frame = +1 Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873 + L L W C +GE +R+ VG V+LQGN+DP LYA R + Sbjct: 265 DTLGLDWTCDIGE--------------ARQRVGSKVSLQGNMDPTVLYARPEAIRQEVAR 310 Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008 +L G VFN+ + + P G F+ VH Sbjct: 311 ILASYGSGTG------HVFNLGHGITPE---VDPANAGAFINAVH 346
Score = 36.2 bits (82), Expect(3) = 1e-12 Identities = 17/27 (62%), Positives = 20/27 (74%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVPQVPTQ 2206 LQPL R+ LDAAI+FSDIL +P Q Sbjct: 61 LQPLDRYPLDAAILFSDILTIPDAMGQ 87
>gi|33594189|ref|NP_881833.1| uroporphyrinogen decarboxylase [Bordetella pertussis] gi|33564264|emb|CAE43556.1| uroporphyrinogen decarboxylase [Bordetella pertussis] Length = 358 Score = 82.8 bits (203), Expect = 5e-14 Identities = 54/159 (33%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + PG+GP F P+R+E D+ +L P++ L YVF A+ R+ L GRVPLI Sbjct: 86 AMGLGLDFAPGEGPRFAHPVRDESDVAKLAVPDM--DSLRYVFDAVRTIRRELDGRVPLI 143 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GFAG+P W + YM EG GS Sbjct: 144 GFAGSP---------------WTI------------------------ACYMAEGRGSDD 164 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K LY RP H++L I +A YL Q+ AGAQ Sbjct: 165 YRLIKSMLYGRPDLLHRILEINAEATRHYLNAQIDAGAQ 203
Score = 35.8 bits (81), Expect = 7.4 Identities = 18/34 (52%), Positives = 21/34 (61%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I+F K G LEE+A G + VGLDWTV AR Sbjct: 247 IVFTKGGGQWLEEIAACGCDAVGLDWTVNLGAAR 280
>gi|23104868|ref|ZP_00091328.1| COG0407: Uroporphyrinogen-III decarboxylase [Azotobacter vinelandii] Length = 355 Score = 82.8 bits (203), Expect = 5e-14 Identities = 56/159 (35%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F + + D+E L P+ +LGYV A+ R+ L GRVPLI Sbjct: 85 AMGLGLYFETGEGPRFRKVVSSPADIEALPVPDP-ERDLGYVMAAVRTIRRELNGRVPLI 143 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 144 GFSGSP--WTLA-------------------------------------TYMVEGGSSKD 164 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 ++K LY PQA H LL L A+ YL GQ++AGAQ Sbjct: 165 FRKSKAMLYDNPQAMHALLDKLARAVTAYLNGQILAGAQ 203
Score = 48.5 bits (114), Expect(3) = 5e-12 Identities = 22/31 (70%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND FLRA + D TPVW MRQAGRYLP Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 42.4 bits (98), Expect = 0.079 Identities = 16/29 (55%), Positives = 23/29 (79%) Frame = +3 Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHS 4319 ++ NLGHG+ P++DP H GAF +AVH+ S Sbjct: 322 HVFNLGHGITPEVDPAHAGAFFEAVHELS 350
Score = 39.7 bits (91), Expect = 0.51 Identities = 35/119 (29%), Positives = 46/119 (38%) Frame = +1 Query: 3652 GQWPQRKPGKPWKGEALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCA 3831 G W + G EAL L W C +G+ +R VG V LQGN+DP Sbjct: 254 GLWLEAMAGSG--AEALGLDWTCDIGD--------------ARARVGGKVALQGNMDPSV 297 Query: 3832 LYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008 LYA+ RA + +L G VFN+ + + P G F VH Sbjct: 298 LYANPAAIRAEVARILARYGAGSG------HVFNLGHGITPE---VDPAHAGAFFEAVH 347
Score = 35.4 bits (80), Expect(3) = 5e-12 Identities = 17/28 (60%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A DF S C +PE CE+TLQ Sbjct: 35 EYRATRAKAGDFMSLCMNPELACEVTLQ 62
Score = 32.0 bits (71), Expect(3) = 5e-12 Identities = 17/23 (73%), Positives = 19/23 (82%), Gaps = 1/23 (4%) Frame = +2 Query: 2126 LQPLRRF-LLDAAIIFSDILVVP 2191 LQPL R+ LDAAI+FSDIL VP Sbjct: 61 LQPLDRYPQLDAAILFSDILTVP 83
>gi|22994377|ref|ZP_00038883.1| COG0407: Uroporphyrinogen-III decarboxylase [Xylella fastidiosa Dixon] Length = 354 Score = 82.8 bits (203), Expect = 5e-14 Identities = 52/159 (32%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+E+ + G+GP +P+R+ + +L P++ +EL YV A+ L R+ L VPLI Sbjct: 82 AMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDM-ETELRYVMDAVRLIRKELDNSVPLI 140 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A YM+EGGGS Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGGSKE 161 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 A K + P HQLL +TDA++ YL Q AGAQ Sbjct: 162 YAHIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQ 200
Score = 45.1 bits (105), Expect = 0.012 Identities = 20/31 (64%), Positives = 22/31 (70%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND LRA + D TP+W MRQAGRYLP Sbjct: 2 LKNDRLLRALRRDTVDRTPIWLMRQAGRYLP 32
Score = 42.0 bits (97), Expect = 0.10 Identities = 17/30 (56%), Positives = 23/30 (76%) Frame = +3 Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322 ++ NLGHG+ P MDP+HV A V+AV + SR Sbjct: 324 HVFNLGHGMTPGMDPDHVSALVEAVQRLSR 353
Score = 40.0 bits (92), Expect(2) = 0.002 Identities = 18/22 (81%), Positives = 21/22 (95%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRRF LDAAI+FSDIL++P Sbjct: 59 LQPLRRFPLDAAILFSDILMIP 80
Score = 38.5 bits (88), Expect = 1.1 Identities = 18/52 (34%), Positives = 31/52 (59%) Frame = +3 Query: 3279 ALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMVRIGMG 3434 ALQ+F++ G L P ++ F+LPY+ +A++++ R G P+V G G Sbjct: 201 ALQVFDTWGGILSPTMYRTFSLPYLTRIARELE---RGTGTEHTPLVLFGKG 249
Score = 26.6 bits (57), Expect(2) = 0.002 Identities = 14/45 (31%), Positives = 20/45 (44%) Frame = +1 Query: 1921 RGGLWRASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQ 2055 R +W + P Y R+ A F ++PE CE+TLQ Sbjct: 18 RTPIWLMRQAGRYLPEYRAARQH--AGSFLKMAKTPELACEITLQ 60
>gi|23138367|ref|ZP_00120028.1| COG0407: Uroporphyrinogen-III decarboxylase [Cytophaga hutchinsonii] Length = 344 Score = 82.4 bits (202), Expect = 7e-14 Identities = 54/159 (33%), Positives = 74/159 (46%) Frame = +1 Query: 2431 QALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPL 2610 +A+G+ M KGP FP+ + D++ L + A L YV+ AI L + L GRVPL Sbjct: 82 EAMGLPYEMQESKGPFFPKVITSAADIDALLATDA-ADHLTYVYDAIELAVKELNGRVPL 140 Query: 2611 IGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSS 2790 IGFAGAP + YM+EG GS Sbjct: 141 IGFAGAP---------------------------------------FTILAYMIEGQGSK 161 Query: 2791 TMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907 T ++A+R+LY P +H+LL +T A + YL QV AGA Sbjct: 162 TFSKARRFLYTEPVLAHRLLEKITLATIAYLKRQVQAGA 200
Score = 57.0 bits (136), Expect = 3e-06 Identities = 28/49 (57%), Positives = 33/49 (67%) Frame = +3 Query: 4161 ALLVPQEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAV 4307 AL + +E+I K+MLD FG +IANLGHGLYPD D V FVDAV Sbjct: 289 ALYLSEEQIRVKAKEMLDAFGTQSHIANLGHGLYPDTDKTKVKCFVDAV 337
Score = 44.3 bits (103), Expect = 0.021 Identities = 20/32 (62%), Positives = 23/32 (71%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 + +ND LRAA GE + TPVW MRQAGR LP Sbjct: 2 QYQNDLILRAARGEAVERTPVWLMRQAGRILP 33
Score = 37.0 bits (84), Expect(2) = 0.053 Identities = 16/28 (57%), Positives = 20/28 (71%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTAR 3858 S++ +G TLQGN+DPCALY SE R Sbjct: 271 SKKIIGPHKTLQGNMDPCALYLSEEQIR 298
Score = 25.0 bits (53), Expect(2) = 0.053 Identities = 10/27 (37%), Positives = 14/27 (51%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTV 3659 +F+K F E+ E VGLDW + Sbjct: 240 VFSKGAFFVREDFNNFPCETVGLDWNM 266
>gi|15603599|ref|NP_246673.1| UroD [Pasteurella multocida] gi|13431433|sp|P57964|DCUP_PASMU Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|12722148|gb|AAK03818.1| UroD [Pasteurella multocida] Length = 354 Score = 82.4 bits (202), Expect = 7e-14 Identities = 54/159 (33%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ ++ G+GP F P+ ++ ++ L P+ EL YV A+ R+ L G VPLI Sbjct: 84 AMGLGLSFGVGEGPKFAHPIETQRAVQNLPIPDP-EGELQYVMNAVRTIRRELKGEVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ LY PQ HQLL L DA++ YL Q+ AGAQ Sbjct: 164 FTKIKKMLYADPQLLHQLLDKLADAVILYLNAQIKAGAQ 202
Score = 47.4 bits (111), Expect(3) = 2e-13 Identities = 21/31 (67%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND +L+A E D TPVW MRQAGRYLP Sbjct: 4 LKNDRYLKALLREPVDMTPVWMMRQAGRYLP 34
Score = 39.7 bits (91), Expect = 0.51 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 1/63 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G S L I Q V+ +L DFG ++ NLGHG++ D+ + FV+A+H+ Sbjct: 288 LQGNMDPSVLYASPARIEQEVRSILADFGEGSGHVFNLGHGIHQDVPEQSPAVFVNAIHQ 347 Query: 4314 HSR 4322 S+ Sbjct: 348 FSQ 350
Score = 38.5 bits (88), Expect(3) = 2e-13 Identities = 17/22 (77%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRR+ LDAAI+FSDIL +P Sbjct: 61 LQPLRRYPLDAAILFSDILTIP 82
Score = 34.7 bits (78), Expect(3) = 2e-13 Identities = 17/28 (60%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A DF S CR+ E CE+TLQ Sbjct: 35 EYRATRAVAGDFMSLCRNAELACEVTLQ 62
Score = 32.3 bits (72), Expect(2) = 0.041 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTV--APKKAR 3677 +F K G LE +A+ G + +G+DWTV A KAR Sbjct: 247 LFTKGGGMWLEAMAETGCDALGVDWTVNLAQAKAR 281
Score = 30.0 bits (66), Expect(2) = 0.041 Identities = 13/19 (68%), Positives = 14/19 (73%) Frame = +1 Query: 3787 VGKTVTLQGNLDPCALYAS 3843 VG V LQGN+DP LYAS Sbjct: 282 VGHKVALQGNMDPSVLYAS 300
>gi|28899690|ref|NP_799295.1| uroporphyrinogen decarboxylase [Vibrio parahaemolyticus RIMD 2210633] gi|31340033|sp|Q87KR0|DCUP_VIBPA Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|28807942|dbj|BAC61179.1| uroporphyrinogen decarboxylase [Vibrio parahaemolyticus] Length = 355 Score = 79.7 bits (195), Expect = 4e-13 Identities = 55/161 (34%), Positives = 74/161 (45%), Gaps = 2/161 (1%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLER--LRDPEVVASELGYVFQAITLTRQRLAGRVP 2607 A+G+ + G+GP F P+ + D+E+ L DPE EL YV A+ R+ L G VP Sbjct: 84 AMGLGLRFAAGEGPVFDNPITCKADVEKIGLPDPE---GELQYVMNAVRQIRKDLNGDVP 140 Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787 LIGF+G+P W A TYMVEGG S Sbjct: 141 LIGFSGSP--WTLA-------------------------------------TYMVEGGSS 161 Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ +Y PQ H LL L D+++ YL Q+ AGAQ Sbjct: 162 KAFTKIKKMMYAEPQTLHLLLDKLADSVIDYLNAQIKAGAQ 202
Score = 53.5 bits (127), Expect(3) = 1e-13 Identities = 24/32 (75%), Positives = 25/32 (78%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA E DYTPVW MRQAGRYLP Sbjct: 3 ELKNDRYLRALLKEPVDYTPVWMMRQAGRYLP 34
Score = 44.3 bits (103), Expect = 0.021 Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310 L G S L E I + V +L+ FG ++ NLGHG++ D+ PE+ G FV+AVH Sbjct: 288 LQGNMDPSMLYASPERIREEVAGILEGFGDAGTGHVFNLGHGIHLDVPPENAGVFVEAVH 347 Query: 4311 KHSR 4322 + S+ Sbjct: 348 ELSK 351
Score = 39.7 bits (91), Expect(3) = 1e-13 Identities = 18/22 (81%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRRF LDAAI+FSDIL +P Sbjct: 61 LQPLRRFPLDAAILFSDILTIP 82
Score = 35.0 bits (79), Expect(2) = 9e-04 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677 +F K+G LE++A G + VGLDWT +A KAR Sbjct: 247 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 281
Score = 33.1 bits (74), Expect(2) = 9e-04 Identities = 27/74 (36%), Positives = 33/74 (44%) Frame = +1 Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966 +G V LQGN+DP LYAS R + +L A VFN L HL Sbjct: 282 IGDKVALQGNMDPSMLYASPERIREEVAGILEGFGDAG-----TGHVFN--LGHGIHL-D 333 Query: 3967 ISPRKTGLFVAVVH 4008 + P G+FV VH Sbjct: 334 VPPENAGVFVEAVH 347
Score = 28.5 bits (62), Expect(3) = 1e-13 Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E++ TRA A DF S C++ E E+TLQ Sbjct: 35 EYKATRAQAGDFMSLCKNAELASEVTLQ 62
>gi|26991750|ref|NP_747175.1| uroporphyrinogen decarboxylase [Pseudomonas putida KT2440] gi|38257478|sp|Q88CV6|DCUP_PSEPK Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|24986857|gb|AAN70639.1| uroporphyrinogen decarboxylase [Pseudomonas putida KT2440] Length = 354 Score = 81.3 bits (199), Expect = 2e-13 Identities = 54/159 (33%), Positives = 73/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F + + D+E L P+ +LGYV A++ R+ L GRVPLI Sbjct: 84 AMGLGLYFETGEGPRFKKVISTPADIEALPVPDP-QKDLGYVMDAVSTIRRELNGRVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKD 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K Y PQA H LL L ++ YL GQ++AGAQ Sbjct: 164 FRKTKAMAYDNPQALHLLLDKLAQSVTSYLNGQILAGAQ 202
Score = 48.5 bits (114), Expect = 0.001 Identities = 26/67 (38%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G + L E I + V ++L +G ++ NLGHG+ P++DPEH GAF++AVH+ Sbjct: 288 LQGNMDPTVLYAKPEAIRKEVARILASYGHGTGHVFNLGHGITPEVDPEHAGAFINAVHE 347 Query: 4314 HSRLLRQ 4334 S Q Sbjct: 348 LSAQYHQ 354
Score = 48.5 bits (114), Expect(3) = 3e-12 Identities = 22/31 (70%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND FLRA + D TPVW MRQAGRYLP Sbjct: 4 LKNDRFLRALLKQPVDVTPVWMMRQAGRYLP 34
Score = 37.0 bits (84), Expect = 3.3 Identities = 30/105 (28%), Positives = 41/105 (39%) Frame = +1 Query: 3694 EALRLRWGCWLGELPCMQLPERGAGFASRECVGKTVTLQGNLDPCALYASEVTARAPLCV 3873 +AL L W C +G+ +R VG V LQGN+DP LYA R + Sbjct: 265 DALGLDWTCEIGD--------------ARRRVGDKVALQGNMDPTVLYAKPEAIRKEVAR 310 Query: 3874 LLLCTPVACGCIILCALVFNVCLSFSSHLYTISPRKTGLFVAVVH 4008 +L G VFN+ + + P G F+ VH Sbjct: 311 ILASYGHGTG------HVFNLGHGITPE---VDPEHAGAFINAVH 346
Score = 35.8 bits (81), Expect(3) = 3e-12 Identities = 16/22 (72%), Positives = 19/22 (86%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL R+ LDAAI+FSDIL +P Sbjct: 61 LQPLDRYPLDAAILFSDILTIP 82
Score = 35.4 bits (80), Expect = 9.7 Identities = 16/34 (47%), Positives = 22/34 (64%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I+F K+G LE +A+AG + +GLDWT AR Sbjct: 246 ILFTKNGGLWLESIAEAGADALGLDWTCEIGDAR 279
Score = 32.3 bits (72), Expect(3) = 3e-12 Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R +RA A DF S C +P+ CE+TLQ Sbjct: 35 EYRASRAKAGDFMSLCMNPQFACEVTLQ 62
>gi|409791|gb|AAC43095.1| uroporphyrinogen decarboxylase Length = 354 Score = 78.2 bits (191), Expect = 1e-12 Identities = 53/159 (33%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K+ +Y PQA H LL L ++ YL Q+ AGAQ Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQ 202
Score = 49.7 bits (117), Expect(3) = 2e-13 Identities = 22/32 (68%), Positives = 24/32 (75%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA + D TPVW MRQAGRYLP Sbjct: 3 ELKNDRYLRALLXQPVDVTPVWMMRQAGRYLP 34
Score = 47.8 bits (112), Expect = 0.002 Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 1/62 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G S L P I + V +L FG ++ NLGHG++ D+ PEH G FV+AVH+ Sbjct: 288 LQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHR 347 Query: 4314 HS 4319 S Sbjct: 348 LS 349
Score = 38.9 bits (89), Expect(3) = 2e-13 Identities = 18/22 (81%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRR+ LDAAI+FSDIL VP Sbjct: 61 LQPLRRYPLDAAILFSDILTVP 82
Score = 32.3 bits (72), Expect(3) = 2e-13 Identities = 15/28 (53%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E++ TRA A DF S C++ E CE+TLQ Sbjct: 35 EYKATRAQAGDFMSLCKNAELACEVTLQ 62
Score = 32.0 bits (71), Expect(2) = 0.041 Identities = 26/78 (33%), Positives = 32/78 (41%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954 +R VG V LQGN+DP LYA + +L G VFN L Sbjct: 278 ARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEG------HVFN--LGHGI 329 Query: 3955 HLYTISPRKTGLFVAVVH 4008 H + P G+FV VH Sbjct: 330 H-QDVPPEHAGVFVEAVH 346
Score = 30.4 bits (67), Expect(2) = 0.041 Identities = 14/33 (42%), Positives = 19/33 (57%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 +F K G LE +A+ G + +GLDWT AR Sbjct: 247 LFTKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
>gi|34496577|ref|NP_900792.1| uroporphyrinogen decarboxylase [Chromobacterium violaceum ATCC 12472] gi|34102431|gb|AAQ58797.1| uroporphyrinogen decarboxylase [Chromobacterium violaceum ATCC 12472] Length = 331 Score = 80.9 bits (198), Expect = 2e-13 Identities = 51/159 (32%), Positives = 70/159 (44%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F PLR+E + L ++ +L YVF A+ R+ L GRVPLI Sbjct: 60 AMGLGLYFAEGEGPKFQRPLRDEAAIRALAPADM--GKLQYVFDAVASIRKALDGRVPLI 117 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P YMVEGGGS Sbjct: 118 GFSGSP---------------------------------------FTLACYMVEGGGSDD 138 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K LY RP+ H +L T +++ YL Q+ AGAQ Sbjct: 139 FRHVKAMLYSRPELLHHILEANTQSVIAYLNAQIDAGAQ 177
Score = 42.0 bits (97), Expect = 0.10 Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Frame = +3 Query: 4158 SALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322 +AL I + V+++L +G ++ NLGHG+ DP H GA V+AVH+ SR Sbjct: 270 NALFAEPAAIEREVERILQSYGQGSGHVFNLGHGISQFADPAHAGALVEAVHRLSR 325
Score = 37.4 bits (85), Expect(3) = 5e-04 Identities = 18/22 (81%), Positives = 19/22 (86%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPL RF LDAAI+FSDIL VP Sbjct: 37 LQPLDRFPLDAAILFSDILTVP 58
Score = 33.1 bits (74), Expect(2) = 0.11 Identities = 16/34 (47%), Positives = 21/34 (61%) Frame = +3 Query: 3576 IIFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 I+F K G LE++A G + VGLDWT +AR Sbjct: 221 IVFTKGGGQWLEDIAAIGADCVGLDWTTDIGQAR 254
Score = 27.7 bits (60), Expect(2) = 0.11 Identities = 13/22 (59%), Positives = 15/22 (68%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYA 3840 +R VG V LQGN DP AL+A Sbjct: 253 ARARVGAKVALQGNFDPNALFA 274
Score = 27.3 bits (59), Expect(3) = 5e-04 Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A F C SP+ E+TLQ Sbjct: 11 EYRATRARAGSFMGLCTSPDYATEVTLQ 38
Score = 23.1 bits (48), Expect(3) = 5e-04 Identities = 9/9 (100%), Positives = 9/9 (100%) Frame = +3 Query: 1833 MRQAGRYLP 1859 MRQAGRYLP Sbjct: 2 MRQAGRYLP 10
>gi|15792567|ref|NP_282390.1| uroporphyrinogen decarboxylase [Campylobacter jejuni] gi|24211637|sp|Q9PN54|DCUP_CAMJE Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|11267841|pir||E81331 uroporphyrinogen decarboxylase (EC 4.1.1.37) Cj1243 [imported] - Campylobacter jejuni (strain NCTC 11168) gi|6968676|emb|CAB73497.1| uroporphyrinogen decarboxylase [Campylobacter jejuni subsp. jejuni NCTC 11168] Length = 340 Score = 80.9 bits (198), Expect = 2e-13 Identities = 53/162 (32%), Positives = 77/162 (47%) Frame = +1 Query: 2422 LPLQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGR 2601 +PL+ +GM + G+GP F P+ +DLE+L D + +L YV+ A+ LTR++L+ Sbjct: 75 VPLE-MGMNLRFEKGEGPVFGNPISTLEDLEKL-DDQNAHKKLNYVYDALKLTREKLSQN 132 Query: 2602 VPLIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGG 2781 LIGF G+P W + TYM+EG Sbjct: 133 KALIGFCGSP---------------WTI------------------------ATYMIEGS 153 Query: 2782 GSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGA 2907 GS A+ K+ LYQ P+ H++L LT L YL Q+ AGA Sbjct: 154 GSKNYAKCKKMLYQNPELLHKILNKLTQVLKLYLEEQIKAGA 195
Score = 40.4 bits (93), Expect = 0.30 Identities = 16/26 (61%), Positives = 20/26 (76%) Frame = +3 Query: 1782 FLRAAWGEETDYTPVWCMRQAGRYLP 1859 F+ A + + T YTP+W MRQAGRYLP Sbjct: 3 FIDACFKKPTPYTPIWMMRQAGRYLP 28
Score = 32.0 bits (71), Expect(2) = 1.1 Identities = 16/22 (72%), Positives = 18/22 (81%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQP+ +DAAIIFSDILVVP Sbjct: 55 LQPIDILDVDAAIIFSDILVVP 76
Score = 25.4 bits (54), Expect(2) = 1.1 Identities = 13/42 (30%), Positives = 20/42 (47%) Frame = +1 Query: 1930 LWRASRLSPVFPLYAEFRETRAAQDFFSTCRSPEACCELTLQ 2055 +W + P Y E R + A DF S C+ + E++LQ Sbjct: 17 IWMMRQAGRYLPEYMEVR--KQAGDFLSLCKDYKKASEVSLQ 56
>gi|37524498|ref|NP_927842.1| uroporphyrinogen decarboxylase [Photorhabdus luminescens subsp. laumondii TTO1] gi|36783922|emb|CAE12784.1| uroporphyrinogen decarboxylase [Photorhabdus luminescens subsp. laumondii TTO1] Length = 354 Score = 80.9 bits (198), Expect = 2e-13 Identities = 55/161 (34%), Positives = 75/161 (46%), Gaps = 2/161 (1%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLR--DPEVVASELGYVFQAITLTRQRLAGRVP 2607 A+G+ + G+GP F P+ D+E+L DPE+ EL YV A+ R+ LAG+VP Sbjct: 84 AMGLGLYFEAGEGPRFKSPVFSRADVEKLPVPDPEM---ELSYVTDAVRAIRKALAGQVP 140 Query: 2608 LIGFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGS 2787 LIGF+G+P W A TYMVEGG S Sbjct: 141 LIGFSGSP--WTLA-------------------------------------TYMVEGGSS 161 Query: 2788 STMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ +Y P H LL L D+++ YL Q+ AGAQ Sbjct: 162 KAFTKIKKMMYAEPTVMHLLLDKLADSVILYLNAQIKAGAQ 202
Score = 49.7 bits (117), Expect = 5e-04 Identities = 29/67 (43%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR-YIANLGHGLYPDMDPEHVGAFVDAVHK 4313 L G S L E I Q V +L FG ++ NLGHG++ D+ PEH G FV+AVHK Sbjct: 288 LQGNMDPSMLYASPERIEQEVSTILQGFGTGSGHVFNLGHGIHQDILPEHAGVFVEAVHK 347 Query: 4314 HSRLLRQ 4334 S Q Sbjct: 348 LSAKYHQ 354
Score = 47.8 bits (112), Expect(2) = 8e-07 Identities = 21/31 (67%), Positives = 23/31 (74%) Frame = +3 Query: 1767 LKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 LKND +LRA + D TPVW MRQAGRYLP Sbjct: 4 LKNDRYLRALLRQSVDVTPVWMMRQAGRYLP 34
Score = 37.4 bits (85), Expect = 2.5 Identities = 20/41 (48%), Positives = 25/41 (60%) Frame = +2 Query: 2069 KRGKDLCLQSAT*QPVSCFLQPLRRFLLDAAIIFSDILVVP 2191 K G + L T LQPL+R+ LDAAI+FSDIL +P Sbjct: 42 KAGDFIALCKNTELACEVTLQPLQRYPLDAAILFSDILTIP 82
Score = 34.7 bits (78), Expect(2) = 0.002 Identities = 28/78 (35%), Positives = 33/78 (42%) Frame = +1 Query: 3775 SRECVGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSS 3954 +R VG V LQGN+DP LYAS + +L G VFN L Sbjct: 278 ARRRVGNKVALQGNMDPSMLYASPERIEQEVSTILQGFGTGSG------HVFN--LGHGI 329 Query: 3955 HLYTISPRKTGLFVAVVH 4008 H I P G+FV VH Sbjct: 330 H-QDILPEHAGVFVEAVH 346
Score = 32.0 bits (71), Expect(2) = 0.002 Identities = 15/33 (45%), Positives = 20/33 (60%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWTVAPKKAR 3677 +FAK G LE +A+ G + +GLDWT AR Sbjct: 247 LFAKGGGQWLEAMAETGCDALGLDWTTDIADAR 279
Score = 30.8 bits (68), Expect(2) = 8e-07 Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E++ TRA A DF + C++ E CE+TLQ Sbjct: 35 EYQATRAKAGDFIALCKNTELACEVTLQ 62
>gi|28198490|ref|NP_778804.1| uroporphyrinogen decarboxylase [Xylella fastidiosa Temecula1] gi|32129491|sp|Q87DV0|DCUP_XYLFT Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|28056574|gb|AAO28453.1| uroporphyrinogen decarboxylase [Xylella fastidiosa Temecula1] Length = 354 Score = 80.9 bits (198), Expect = 2e-13 Identities = 51/159 (32%), Positives = 74/159 (46%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+E+ + G+GP +P+R+ + +L P++ +EL YV A+ L R+ L VPLI Sbjct: 82 AMGLELHFIEGEGPRLGKPIRDAAAITQLAVPDM-ETELRYVMDAVRLIRKELDNSVPLI 140 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A YM+EGG S Sbjct: 141 GFSGSP--WTLA-------------------------------------CYMIEGGSSKE 161 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 A+ K + P HQLL +TDA++ YL Q AGAQ Sbjct: 162 YARIKAMAFNAPDVLHQLLNTVTDAVISYLAAQRAAGAQ 200
Score = 40.0 bits (92), Expect = 0.39 Identities = 16/30 (53%), Positives = 23/30 (76%) Frame = +3 Query: 4233 YIANLGHGLYPDMDPEHVGAFVDAVHKHSR 4322 ++ NLGHG+ P M+P+HV A V+AV + SR Sbjct: 324 HVFNLGHGMTPGMNPDHVSALVEAVQRLSR 353
>gi|15640359|ref|NP_229986.1| uroporphyrinogen decarboxylase [Vibrio cholerae O1 biovar eltor str. N16961] gi|11267825|pir||C82335 uroporphyrinogen decarboxylase VC0332 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi|9654747|gb|AAF93505.1| uroporphyrinogen decarboxylase [Vibrio cholerae O1 biovar eltor str. N16961] Length = 359 Score = 77.4 bits (189), Expect = 2e-12 Identities = 50/159 (31%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ + D++++ P+ EL YV A+ R+ L G VPLI Sbjct: 88 AMGLGLRFAAGEGPVFERPITCKADVDKIGIPDP-EGELQYVMNAVRQIRKDLQGEVPLI 146 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 147 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 167 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ +Y P H LL L D+++ YL Q+ AGAQ Sbjct: 168 FTKIKKMMYSEPTVLHALLDKLADSVISYLNAQIKAGAQ 206
Score = 52.4 bits (124), Expect(3) = 2e-13 Identities = 23/32 (71%), Positives = 25/32 (78%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA + DYTPVW MRQAGRYLP Sbjct: 7 ELKNDRYLRALLKQPVDYTPVWMMRQAGRYLP 38
Score = 44.3 bits (103), Expect = 0.021 Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310 L G S L P I + V +L FG ++ NLGHG++ D+ PE+ G FV+AVH Sbjct: 292 LQGNMDPSILYAPAPRIREEVASILAGFGQGGTGHVFNLGHGIHLDVPPENAGVFVEAVH 351 Query: 4311 KHSR 4322 + S+ Sbjct: 352 ELSK 355
Score = 39.7 bits (91), Expect(3) = 2e-13 Identities = 18/22 (81%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRRF LDAAI+FSDIL +P Sbjct: 65 LQPLRRFPLDAAILFSDILTIP 86
Score = 35.0 bits (79), Expect(2) = 0.002 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677 +F K+G LE++A G + VGLDWT +A KAR Sbjct: 251 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 285
Score = 31.6 bits (70), Expect(2) = 0.002 Identities = 26/74 (35%), Positives = 31/74 (41%) Frame = +1 Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966 VG V LQGN+DP LYA R + +L VFN L HL Sbjct: 286 VGDKVALQGNMDPSILYAPAPRIREEVASILAGFGQGG-----TGHVFN--LGHGIHL-D 337 Query: 3967 ISPRKTGLFVAVVH 4008 + P G+FV VH Sbjct: 338 VPPENAGVFVEAVH 351
Score = 28.5 bits (62), Expect(3) = 2e-13 Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A DF + C++ E E+TLQ Sbjct: 39 EYRATRAQAGDFMALCKNAELASEVTLQ 66
>gi|23814028|sp|Q9KV26|DCUP_VIBCH Uroporphyrinogen decarboxylase (URO-D) (UPD) Length = 355 Score = 77.4 bits (189), Expect = 2e-12 Identities = 50/159 (31%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ + D++++ P+ EL YV A+ R+ L G VPLI Sbjct: 84 AMGLGLRFAAGEGPVFERPITCKADVDKIGIPDP-EGELQYVMNAVRQIRKDLQGEVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 + K+ +Y P H LL L D+++ YL Q+ AGAQ Sbjct: 164 FTKIKKMMYSEPTVLHALLDKLADSVISYLNAQIKAGAQ 202
Score = 52.4 bits (124), Expect(3) = 2e-13 Identities = 23/32 (71%), Positives = 25/32 (78%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA + DYTPVW MRQAGRYLP Sbjct: 3 ELKNDRYLRALLKQPVDYTPVWMMRQAGRYLP 34
Score = 44.3 bits (103), Expect = 0.021 Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Frame = +3 Query: 4137 LAGPPVASALLVPQEEIGQLVKQMLDDFGPHR--YIANLGHGLYPDMDPEHVGAFVDAVH 4310 L G S L P I + V +L FG ++ NLGHG++ D+ PE+ G FV+AVH Sbjct: 288 LQGNMDPSILYAPAPRIREEVASILAGFGQGGTGHVFNLGHGIHLDVPPENAGVFVEAVH 347 Query: 4311 KHSR 4322 + S+ Sbjct: 348 ELSK 351
Score = 39.7 bits (91), Expect(3) = 2e-13 Identities = 18/22 (81%), Positives = 20/22 (90%) Frame = +2 Query: 2126 LQPLRRFLLDAAIIFSDILVVP 2191 LQPLRRF LDAAI+FSDIL +P Sbjct: 61 LQPLRRFPLDAAILFSDILTIP 82
Score = 35.0 bits (79), Expect(2) = 0.002 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 2/35 (5%) Frame = +3 Query: 3579 IFAKDGHFALEELAQAGYEVVGLDWT--VAPKKAR 3677 +F K+G LE++A G + VGLDWT +A KAR Sbjct: 247 LFTKNGGMWLEQIAATGCDAVGLDWTINIADAKAR 281
Score = 31.6 bits (70), Expect(2) = 0.002 Identities = 26/74 (35%), Positives = 31/74 (41%) Frame = +1 Query: 3787 VGKTVTLQGNLDPCALYASEVTARAPLCVLLLCTPVACGCIILCALVFNVCLSFSSHLYT 3966 VG V LQGN+DP LYA R + +L VFN L HL Sbjct: 282 VGDKVALQGNMDPSILYAPAPRIREEVASILAGFGQGG-----TGHVFN--LGHGIHL-D 333 Query: 3967 ISPRKTGLFVAVVH 4008 + P G+FV VH Sbjct: 334 VPPENAGVFVEAVH 347
Score = 28.5 bits (62), Expect(3) = 2e-13 Identities = 14/28 (50%), Positives = 19/28 (67%), Gaps = 1/28 (3%) Frame = +1 Query: 1975 EFRETRA-AQDFFSTCRSPEACCELTLQ 2055 E+R TRA A DF + C++ E E+TLQ Sbjct: 35 EYRATRAQAGDFMALCKNAELASEVTLQ 62
>gi|15834174|ref|NP_312947.1| uroporphyrinogen decarboxylase [Escherichia coli O157:H7] gi|23813992|sp|Q8X6X5|DCUP_ECO57 Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|25291010|pir||H91243 uroporphyrinogen decarboxylase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) gi|13364396|dbj|BAB38343.1| uroporphyrinogen decarboxylase [Escherichia coli O157:H7] Length = 354 Score = 78.2 bits (191), Expect = 1e-12 Identities = 53/159 (33%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K+ +Y PQA H LL L ++ YL Q+ AGAQ Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAGAQ 202
Score = 49.3 bits (116), Expect(3) = 2e-13 Identities = 22/32 (68%), Positives = 24/32 (75%) Frame = +3 Query: 1764 ELKNDTFLRAAWGEETDYTPVWCMRQAGRYLP 1859 ELKND +LRA + D TPVW MRQAGRYLP Sbjct: 3 ELKNDRYLRALLRQPVDVTPVWMMRQAGRYLP 34
>gi|16131827|ref|NP_418425.1| uroporphyrinogen decarboxylase [Escherichia coli K12] gi|1352226|sp|P29680|DCUP_ECOLI Uroporphyrinogen decarboxylase (URO-D) (UPD) gi|7436556|pir||H65206 uroporphyrinogen decarboxylase (EC 4.1.1.37) - Escherichia coli (strain K-12) gi|2367337|gb|AAC76971.1| uroporphyrinogen decarboxylase [Escherichia coli K12] Length = 354 Score = 78.2 bits (191), Expect = 1e-12 Identities = 53/159 (33%), Positives = 72/159 (45%) Frame = +1 Query: 2434 ALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLI 2613 A+G+ + G+GP F P+ + D+++L P+ ELGYV A+ R+ L G VPLI Sbjct: 84 AMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDP-EDELGYVMNAVRTIRRELKGEVPLI 142 Query: 2614 GFAGAPVMWDRAGTRGAGRSLWKVWGRQKEGSVXXXXXXXXXXXXXXXMTYMVEGGGSST 2793 GF+G+P W A TYMVEGG S Sbjct: 143 GFSGSP--WTLA-------------------------------------TYMVEGGSSKA 163 Query: 2794 MAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQ 2910 K+ +Y PQA H LL L ++ YL Q+ AGAQ Sbjct: 164 FTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQ 202
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF Posted date: Nov 24, 2003 12:35 AM Number of letters in database: 504,792,447 Number of sequences in database: 1,544,637 Lambda K H 0.318 0.135 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 460,766,415 Number of Sequences: 1544637 Number of extensions: 11433435 Number of successful extensions: 34058 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 25246 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 33960 length of database: 504,792,447 effective HSP length: 137 effective length of database: 293,177,178 effective search space used: 400773202326 frameshift window, decay const: 50, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)