BLASTP 2.2.26+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Stephen F. Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. RID: GXZGKJW7012 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 16,927,445 sequences; 5,811,956,865 total letters Query= supercont1.626:subseq(0,50000) of Sphaeroforma arctica JP610:[translate(1)] Length=118 Score E Sequences producing significant alignments: (Bits) Value gb|ABY62740.1| phospholipid-hydroperoxide glutathione peroxid... 137 6e-40 gb|AEI70684.1| GPx isotype 3 [Perinereis nuntia] 133 2e-38 gb|ABA62395.1| phospholipid-hydroperoxide glutathione peroxid... 132 7e-38 ref|NP_001165215.1| glutathione peroxidase 4 a [Xenopus laevis] 132 8e-38 gb|ACF72883.1| glutathione peroxidase 4B [Danio rerio] 131 1e-37 ref|NP_001025241.2| glutathione peroxidase 4b [Danio rerio] 132 1e-37 gb|AAO86705.1| phospholipid hydroperoxide glutathione peroxid... 131 1e-37 gb|ABA62390.1| phospholipid-hydroperoxide glutathione peroxid... 131 2e-37 gb|ACR33822.1| glutathione peroxidase 4b [Cyprinus carpio] 131 2e-37 gb|ACH86324.1| glutathione peroxidase 4b [Salmo salar] 131 3e-37 gb|ABA62394.1| phospholipid-hydroperoxide glutathione peroxid... 130 3e-37 ref|NP_001165213.1| glutathione peroxidase 4 b [Xenopus laevis] 130 3e-37 gb|ABA62391.1| phospholipid-hydroperoxide glutathione peroxid... 130 4e-37 gb|ABA25916.1| phospholipid-hydroperoxide glutathione peroxid... 130 6e-37 gb|ABA62393.1| phospholipid-hydroperoxide glutathione peroxid... 129 6e-37 dbj|BAH70830.1| ACYPI38240 [Acyrthosiphon pisum] 129 2e-36 gb|AAA31099.2| phospholipid hydroperoxide glutathione peroxid... 128 2e-36 gb|ABU41109.1| phospholipid-hydroperoxide glutathione peroxid... 129 2e-36 ref|NP_999572.1| phospholipid hydroperoxide glutathione perox... 128 4e-36 gb|ABA62388.1| phospholipid-hydroperoxide glutathione peroxid... 127 4e-36 ref|NP_777195.1| phospholipid hydroperoxide glutathione perox... 128 4e-36 gb|ACT53163.2| phospholipid hydroperoxide glutathione peroxid... 128 4e-36 gb|ABU41074.1| phospholipid-hydroperoxide glutathione peroxid... 128 5e-36 gb|AAM18080.2|AF498316_1 phospholipid hydroperoxide glutathio... 127 9e-36 gb|ACP44070.1| phospholipid hydroperoxide glutathione peroxid... 126 1e-35 gb|ACZ67681.1| phospholipid hydroperoxide glutathione peroxid... 127 1e-35 ref|XP_003393108.1| PREDICTED: probable phospholipid hydroper... 126 1e-35 ref|XP_003393107.1| PREDICTED: probable phospholipid hydroper... 126 1e-35 gb|AAB21327.2| phospholipid hydroperoxide glutathione peroxid... 125 2e-35 gb|ACF35507.1| phospholipid-hydroperoxide glutathione peroxid... 125 2e-35 gb|ABC25027.1| phospholipid hydroperoxide glutathione peroxid... 125 3e-35 gb|AAO86704.1| phospholipid hydroperoxide glutathione peroxid... 124 5e-35 gb|ABC25026.1| mitochondrial phospholipid hydroperoxide gluta... 125 5e-35 sp|Q32QL6.2|GPX4_CALJA RecName: Full=Phospholipid hydroperoxi... 125 5e-35 ref|NP_001007283.2| glutathione peroxidase 4 precursor [Danio... 125 6e-35 gb|ABW76146.1| glutathione peroxidase 4a [Danio rerio] 125 6e-35 pdb|2OBI|A Chain A, Crystal Structure Of The Selenocysteine T... 125 8e-35 ref|NP_001120347.1| glutathione peroxidase 4 precursor [Xenop... 125 8e-35 ref|NP_002076.2| phospholipid hydroperoxide glutathione perox... 125 8e-35 emb|CAA50793.1| phospholipid hydroperoxide glutathione peroxi... 125 8e-35 ref|XP_003340790.1| PREDICTED: LOW QUALITY PROTEIN: phospholi... 125 9e-35 ref|NP_001112361.1| glutathione peroxidase 4 precursor [Macac... 125 1e-34 ref|NP_001034936.1| phospholipid hydroperoxide glutathione pe... 125 1e-34 pdb|2GS3|A Chain A, Crystal Structure Of The Selenocysteine T... 124 1e-34 gb|ABD75380.1| phospholipid hydroperoxide glutathione peroxid... 124 1e-34 sp|Q4AEG9.2|GPX4_CEBAP RecName: Full=Phospholipid hydroperoxi... 124 1e-34 gb|AAH46163.1| Glutathione peroxidase 4 (phospholipid hydrope... 124 1e-34 ref|XP_003429587.1| PREDICTED: LOW QUALITY PROTEIN: phospholi... 124 2e-34 ref|NP_001177287.1| glutathione peroxidase_like protein e [Ci... 124 2e-34 gb|ACN78879.1| glutathione peroxidase 4 [Anguilla japonica] 123 3e-34 emb|CAD61277.1| phospholipid hydroperoxide glutathione peroxi... 122 3e-34 ref|NP_001034937.1| phospholipid hydroperoxide glutathione pe... 124 4e-34 ref|NP_001139295.1| glutathione peroxidase 4 [Pan troglodytes] 124 4e-34 gb|ABK23808.1| unknown [Picea sitchensis] 124 4e-34 gb|AAC15833.1| phospholipid hydroperoxide glutathione peroxid... 122 4e-34 gb|AAH83137.2| Gpx4 protein [Mus musculus] 122 5e-34 gb|AAA41842.2| phospholipid hydroperoxide glutathione peroxid... 122 5e-34 emb|CAA57996.1| phospholipid hydroperoxide glutathione peroxi... 122 5e-34 gb|AAC52503.2| phospholipid hydroperoxide glutathione peroxid... 123 5e-34 dbj|BAA92142.1| phospholipid hydroperoxide glutathione peroxi... 122 6e-34 gb|ADI56239.1| glutathione peroxidase [Hydra vulgaris] 122 6e-34 ref|NP_032188.3| phospholipid hydroperoxide glutathione perox... 123 6e-34 gb|ACR33821.1| glutathione peroxidase 4a [Cyprinus carpio] 122 6e-34 gb|ABO38818.2| phospholipid hydroperoxide glutathione peroxid... 122 7e-34 gb|AEG78385.1| phospholipid hydroperoxide glutathione peroxid... 122 7e-34 ref|NP_058861.3| phospholipid hydroperoxide glutathione perox... 122 8e-34 dbj|BAA22780.1| phospholipid hydroperoxide glutathione peroxi... 122 1e-33 ref|YP_003369419.1| glutathione peroxidase [Pirellula staleyi... 122 1e-33 ref|NP_001036999.1| glutathione peroxidase [Bombyx mori] >dbj... 122 1e-33 gb|EFN75696.1| Probable phospholipid hydroperoxide glutathion... 121 1e-33 sp|Q4AEH0.2|GPX4_MACFU RecName: Full=Phospholipid hydroperoxi... 122 1e-33 sp|Q4AEH1.2|GPX4_HYLLA RecName: Full=Phospholipid hydroperoxi... 122 2e-33 ref|XP_969867.1| PREDICTED: similar to glutathione peroxidase... 122 2e-33 ref|XP_002429001.1| phospholipid hydroperoxide glutathione pe... 120 2e-33 gb|ABK58680.1| PHGPx isoform 2 [Clonorchis sinensis] 120 3e-33 ref|XP_002272606.1| PREDICTED: probable phospholipid hydroper... 120 3e-33 ref|XP_002979231.1| hypothetical protein SELMODRAFT_228619 [S... 122 4e-33 gb|AEI91049.1| glutathione peroxidase 4 variant 1 [Seriola la... 120 4e-33 emb|CAM34513.1| putative phospholipid hydroperoxide glutathio... 120 4e-33 gb|ADI58543.1| glutathione peroxidase 1 [Brassica napus] >gb|... 122 4e-33 emb|CAD61278.1| phospholipid hydroperoxide glutathione peroxi... 122 4e-33 emb|CAL59721.1| glutathione peroxidase [Medicago sativa] 122 5e-33 gb|AEI91050.1| glutathione peroxidase 4 variant 2 [Seriola la... 120 5e-33 dbj|BAJ33870.1| unnamed protein product [Thellungiella haloph... 121 5e-33 sp|Q91XR9.3|GPX42_MOUSE RecName: Full=Phospholipid hydroperox... 122 6e-33 ref|XP_003427378.1| PREDICTED: probable phospholipid hydroper... 120 6e-33 ref|NP_001032830.2| phospholipid hydroperoxide glutathione pe... 122 6e-33 ref|NP_001034938.1| phospholipid hydroperoxide glutathione pe... 122 7e-33 ref|NP_001171492.1| glutathione peroxidase-like 1 [Apis melli... 119 7e-33 emb|CAJ43709.1| glutathion peroxidase [Plantago major] 119 9e-33 ref|XP_003588874.1| Glutathione peroxidase [Medicago truncatu... 121 1e-32 ref|XP_003439917.1| PREDICTED: LOW QUALITY PROTEIN: phospholi... 119 1e-32 ref|NP_001177284.1| glutathione peroxidase_like protein d pre... 120 1e-32 gb|ACJ84092.1| unknown [Medicago truncatula] 120 1e-32 gb|AAK74113.1|AF274028_1 phospholipid hydroperoxide glutathio... 121 1e-32 ref|XP_002990305.1| hypothetical protein SELMODRAFT_16028 [Se... 118 1e-32 dbj|BAC87836.1| nucleolar phospholipid hydroperoxide glutathi... 121 1e-32 gb|EFN70618.1| Probable phospholipid hydroperoxide glutathion... 119 1e-32 gb|ACZ66012.1| phospholipid hydroperoxide glutathione peroxid... 119 1e-32 gb|ADG21870.1| phospholipid hydroperoxide glutathione peroxid... 118 1e-32 ALIGNMENTS >gb|ABY62740.1| phospholipid-hydroperoxide glutathione peroxidase [Artemia franciscana] Length=155 Score = 137 bits (344), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 64/114 (56%), Positives = 84/114 (74%), Gaps = 6/114 (5%) Query 5 VYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILAF 64 +Y FT K IDG+E+ +E Y+G V V VNVAS+ G T+ +YTQL L +YR+KGL++LAF Sbjct 5 IYDFTAKDIDGNEVSLEKYRGKVCVIVNVASKUGKTRVSYTQLVELHNKYREKGLEVLAF 64 Query 65 PCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 PCNQFG GQEP ++ EIKKFA + VKF +FSKI+VNGS A P+W ++K Sbjct 65 PCNQFG------GQEPAAEPEIKKFAQSYGVKFDMFSKINVNGSDAHPLWNFLK 112 >gb|AEI70684.1| GPx isotype 3 [Perinereis nuntia] Length=148 Score = 133 bits (334), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 66/107 (62%), Positives = 84/107 (79%), Gaps = 7/107 (7%) Query 13 IDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILAFPCNQFGKY 72 IDG+++ + YKG+V + VNVAS+ GLT NYTQL+AL + DKGL+ILAFP NQFGK Sbjct 1 IDGNDVSLSQYKGHVCLIVNVASKGGLTDKNYTQLQALHEELADKGLRILAFPSNQFGK- 59 Query 73 TCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 QEPGS+ EIK+FA SK+NVKF +FSKIDVNG+ ADP+W+Y+K Sbjct 60 -----QEPGSNEEIKQFATSKYNVKFDMFSKIDVNGNGADPLWKYLK 101 >gb|ABA62395.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 132 bits (331), Expect = 7e-38, Method: Compositional matrix adjust. Identities = 63/116 (54%), Positives = 87/116 (75%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L ++Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHKKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++A+IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTEADIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >ref|NP_001165215.1| glutathione peroxidase 4 a [Xenopus laevis] Length=196 Score = 132 bits (333), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 62/118 (53%), Positives = 85/118 (72%), Gaps = 6/118 (5%) Query 1 AYQNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLK 60 A +++Y F+ IDG+E+ +E Y+G V + VNVAS+ G T NYTQLE L +Y +KGL+ Sbjct 36 AAKSIYEFSAVDIDGNEVSLEKYRGYVCIIVNVASKUGKTPVNYTQLEELHAKYAEKGLR 95 Query 61 ILAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 IL FPCNQFGK QEPG +++IK FA+ + V+F +FSKIDVNG A P+W++MK Sbjct 96 ILGFPCNQFGK------QEPGDESQIKVFAASYKVEFDMFSKIDVNGDGAHPLWKWMK 147 >gb|ACF72883.1| glutathione peroxidase 4B [Danio rerio] Length=170 Score = 131 bits (330), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y F+ IDG+++ +E Y+G V + NVAS+ G T NYTQL A+ Y +KGL+IL Sbjct 12 KSIYEFSAIDIDGNDVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHVTYAEKGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPGS+AEIK+FA +N +F LFSKIDVNG +A P+W++MK Sbjct 72 GFPCNQFGK------QEPGSEAEIKEFAKGYNAEFDLFSKIDVNGDAAHPLWKWMK 121 >ref|NP_001025241.2| glutathione peroxidase 4b [Danio rerio] Length=191 Score = 132 bits (332), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y F+ IDG+++ +E Y+G V + NVAS+ G T NYTQL A+ Y +KGL+IL Sbjct 33 KSIYEFSAIDIDGNDVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHVTYAEKGLRIL 92 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPGS+AEIK+FA +N +F LFSKIDVNG +A P+W++MK Sbjct 93 GFPCNQFGK------QEPGSEAEIKEFAKGYNAEFDLFSKIDVNGDAAHPLWKWMK 142 >gb|AAO86705.1| phospholipid hydroperoxide glutathione peroxidase B [Danio rerio] Length=169 Score = 131 bits (330), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y F+ IDG+++ +E Y+G V + NVAS+ G T NYTQL A+ Y +KGL+IL Sbjct 11 KSIYEFSAIDIDGNDVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHVTYAEKGLRIL 70 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPGS+AEIK+FA +N +F LFSKIDVNG +A P+W++MK Sbjct 71 GFPCNQFGK------QEPGSEAEIKEFAKGYNAEFDLFSKIDVNGDAAHPLWKWMK 120 >gb|ABA62390.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 131 bits (329), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 63/116 (54%), Positives = 86/116 (74%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L +Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHEKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++A+IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTEADIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >gb|ACR33822.1| glutathione peroxidase 4b [Cyprinus carpio] Length=166 Score = 131 bits (329), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y F+ K IDG+E+ +E Y+G V + NVAS+ G T NYTQL A+ Y +KGL+IL Sbjct 12 KSIYEFSAKDIDGNEVSLEKYRGYVCIITNVASKUGKTPVNYTQLAAMHATYAEKGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPG++AEIK+FA + +F LFSKI+VNG A P+W++MK Sbjct 72 GFPCNQFGK------QEPGTEAEIKEFAKGYKAEFDLFSKIEVNGDGAHPLWKWMK 121 >gb|ACH86324.1| glutathione peroxidase 4b [Salmo salar] Length=179 Score = 131 bits (329), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 61/114 (54%), Positives = 82/114 (72%), Gaps = 6/114 (5%) Query 5 VYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILAF 64 +Y F K IDG+++ +E Y+G V V NVAS+ G T+ NYTQLE + Y DKGL+IL F Sbjct 21 IYEFGAKDIDGEDVSLEKYRGFVCVITNVASKUGKTRVNYTQLEGMHASYADKGLRILGF 80 Query 65 PCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 PCNQFG GQEPG++ EIK+F +F+V+F +FSKIDVNG A P++++MK Sbjct 81 PCNQFG------GQEPGTEVEIKEFVKQFDVQFDMFSKIDVNGDGAHPLFKWMK 128 >gb|ABA62394.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 130 bits (328), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 86/116 (74%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L ++Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHKKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++ +IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTETDIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >ref|NP_001165213.1| glutathione peroxidase 4 b [Xenopus laevis] Length=170 Score = 130 bits (328), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 62/118 (53%), Positives = 84/118 (71%), Gaps = 6/118 (5%) Query 1 AYQNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLK 60 A +++Y F+ IDG+E+ +E Y+G V + VNVAS+ G T NYTQL L +Y +KGL+ Sbjct 10 AAKSIYEFSAVDIDGNEVSLEKYRGYVCIIVNVASKUGKTPVNYTQLVELHARYAEKGLR 69 Query 61 ILAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 IL FPCNQFGK QEPG +A+IK FA+ + V+F +FSKIDVNG A P+W++MK Sbjct 70 ILGFPCNQFGK------QEPGDEAQIKDFAASYKVEFDMFSKIDVNGDGAHPLWKWMK 121 >gb|ABA62391.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 130 bits (327), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 63/116 (54%), Positives = 85/116 (73%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 + Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L +Y + KGL+IL Sbjct 13 STYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHEKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++A+IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTEADIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >gb|ABA25916.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] gb|ABA62389.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] gb|ABA62392.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 130 bits (326), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 85/116 (73%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L +Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHEKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++ +IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTETDIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >gb|ABA62393.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=170 Score = 129 bits (325), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 85/116 (73%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G T NYTQL L +Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYTQLVELHEKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++ +IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTETDIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >dbj|BAH70830.1| ACYPI38240 [Acyrthosiphon pisum] Length=203 Score = 129 bits (324), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 63/116 (54%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++VY FT K I G+++ +E YKG V++ VNVAS+ G T +Y +L LD +YRDKGLKIL Sbjct 47 KSVYDFTVKDIKGEDVSLEKYKGCVLIIVNVASKCGYTSKHYKELIELDEKYRDKGLKIL 106 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG GQEPG I F +K NVKF +F KIDVNG+ A P+W+Y+K Sbjct 107 GFPCNQFG------GQEPGDADSICSFTAKQNVKFDIFEKIDVNGNDAHPLWKYLK 156 >gb|AAA31099.2| phospholipid hydroperoxide glutathione peroxidase [Sus scrofa] emb|CAA53595.2| phospholipid hydroperoxide glutathione peroxidase [Sus scrofa] emb|CAA53596.2| phospholipid hydroperoxide glutathione peroxidase [Sus scrofa] Length=170 Score = 128 bits (322), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 12 RSMHEFSAKDIDGHMVNLDKYRGYVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGSDAEIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSDAEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 121 >gb|ABU41109.1| phospholipid-hydroperoxide glutathione peroxidase [Lepeophtheirus salmonis] Length=184 Score = 129 bits (323), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 63/116 (54%), Positives = 87/116 (75%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 N+Y FT IDG+E+ ME Y+G+V + +NVASE G K NYTQL L ++Y + +GL+IL Sbjct 27 NIYGFTALDIDGNEVSMEKYRGHVCIILNVASEUGKXKVNYTQLVELFKKYSETEGLRIL 86 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPG++AEIK++A+K+ V+F LFSKI+VNG A P+++Y+K Sbjct 87 AFPCNQFGN------QEPGTNAEIKEYAAKYGVQFDLFSKINVNGPDAHPLFKYLK 136 >ref|NP_999572.1| phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor [Sus scrofa] sp|P36968.3|GPX4_PIG RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor gb|AAA31098.2| phospholipid hydroperoxide glutathione peroxidase [Sus scrofa] Length=197 Score = 128 bits (322), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGYVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGSDAEIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSDAEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >gb|ABA62388.1| phospholipid-hydroperoxide glutathione peroxidase [Rhipicephalus microplus] Length=169 Score = 127 bits (320), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F+ IDG+E+ ++ YKG+V + VNVAS+ G NYTQL L +Y + KGL+IL Sbjct 13 SIYDFSAVDIDGNEVSLDKYKGHVALIVNVASKUGKANKNYTQLVELHEKYAESKGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++ +IKKF K+NVKF +FSK++VNG A P+W+Y+K Sbjct 73 AFPCNQFG------GQEPGTETDIKKFVEKYNVKFDMFSKVNVNGDKAHPLWKYLK 122 >ref|NP_777195.1| phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor [Bos taurus] sp|Q9N2J2.2|GPX4_BOVIN RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor dbj|BAA86034.1| phospholipid hydroperoxide glutathione peroxidase [Bos taurus] gb|DAA27471.1| phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor [Bos taurus] Length=197 Score = 128 bits (322), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G+V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGRMVNLDKYRGHVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+AEIK+FA+ +NVKF LFSKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSNAEIKEFAAGYNVKFDLFSKICVNGDDAHPLWKWMK 148 >gb|ACT53163.2| phospholipid hydroperoxide glutathione peroxidase 4 [Capra hircus] gb|ACY69862.1| phospholipid hydroperoxide glutathione peroxidase 4 [Capra hircus] Length=200 Score = 128 bits (322), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G+V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 42 RSMHEFSAKDIDGRMVNLDKYRGHVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 101 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+AEIK+FA+ +NVKF LFSKI VNG A P+W++MK Sbjct 102 AFPCNQFGR------QEPGSNAEIKEFAAGYNVKFDLFSKICVNGDDAHPLWKWMK 151 >gb|ABU41074.1| phospholipid-hydroperoxide glutathione peroxidase [Lepeophtheirus salmonis] Length=195 Score = 128 bits (321), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 62/116 (53%), Positives = 87/116 (75%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 N+Y FT IDG+E+ ME Y+G+V + +NVASE G K NYTQL L ++Y + +GL+IL Sbjct 38 NIYGFTALDIDGNEVSMEKYRGHVCIILNVASEUGKAKVNYTQLVELFKKYSETEGLRIL 97 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPG++AEIK++A+K+ V+F +FSKI+VNG A P+++Y+K Sbjct 98 AFPCNQFG------NQEPGTNAEIKEYAAKYGVQFDMFSKINVNGPDAHPLFKYLK 147 >gb|AAM18080.2|AF498316_1 phospholipid hydroperoxide glutathione peroxidase [Gallus gallus] Length=170 Score = 127 bits (318), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 60/115 (52%), Positives = 80/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F + IDG ++ +E Y+G V + NVAS+ G T NYTQL L +Y +KGL+ILA Sbjct 13 SIYDFHARDIDGRDVSLEQYRGFVCIITNVASKUGKTAVNYTQLVDLHARYAEKGLRILA 72 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPG DA+IK FA + VKF +FSKI+VNG A P+W+++K Sbjct 73 FPCNQFGK------QEPGDDAQIKAFAEGYGVKFDMFSKIEVNGDGAHPLWKWLK 121 >gb|ACP44070.1| phospholipid hydroperoxide glutathione peroxidase [Bombus ignitus] gb|ACP44071.1| phospholipid hydroperoxide glutathione peroxidase [Bombus ignitus] Length=168 Score = 126 bits (317), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 64/117 (55%), Positives = 80/117 (68%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 +++Y FT KSI G+E+P+ YKG+V + VNVAS+ GLT NY QL L +Y D KGL+I Sbjct 11 KSIYDFTAKSIKGEEVPLSNYKGHVCLIVNVASKCGLTATNYKQLNELYDEYADSKGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF GQEPG EI FA + VKF +F KIDVNG A P+W+Y+K Sbjct 71 LAFPCNQF------NGQEPGGTEEICSFADRQQVKFDIFEKIDVNGDKAHPLWKYLK 121 >gb|ACZ67681.1| phospholipid hydroperoxide glutathione peroxidase-4 [Meleagris gallopavo] Length=188 Score = 127 bits (318), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 60/115 (52%), Positives = 80/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F + IDG ++ +E Y+G V + NVAS+ G T NYTQL L +Y +KGL+ILA Sbjct 31 SMYDFHARDIDGHDVALERYRGFVCIVTNVASKUGKTAVNYTQLVDLHARYAEKGLRILA 90 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPG +A+IK FA + VKF +FSKI+VNG A P+W++MK Sbjct 91 FPCNQFGK------QEPGDEAQIKAFAEGYGVKFDMFSKIEVNGDGAHPLWKWMK 139 >ref|XP_003393108.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase-like isoform 2 [Bombus terrestris] ref|XP_003492178.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase-like [Bombus impatiens] Length=168 Score = 126 bits (316), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 64/117 (55%), Positives = 80/117 (68%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 +++Y FT KSI G+E+P+ YKG+V + VNVAS+ GLT NY QL L +Y D KGL+I Sbjct 11 KSIYDFTAKSIKGEEVPLSNYKGHVCLIVNVASKCGLTATNYKQLNELYDEYADSKGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF GQEPG EI FA + VKF +F KIDVNG A P+W+Y+K Sbjct 71 LAFPCNQF------NGQEPGGTEEICSFADRQKVKFDIFEKIDVNGDKAHPLWKYLK 121 >ref|XP_003393107.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase-like isoform 1 [Bombus terrestris] Length=176 Score = 126 bits (317), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 64/117 (55%), Positives = 80/117 (68%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 +++Y FT KSI G+E+P+ YKG+V + VNVAS+ GLT NY QL L +Y D KGL+I Sbjct 19 KSIYDFTAKSIKGEEVPLSNYKGHVCLIVNVASKCGLTATNYKQLNELYDEYADSKGLRI 78 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF GQEPG EI FA + VKF +F KIDVNG A P+W+Y+K Sbjct 79 LAFPCNQF------NGQEPGGTEEICSFADRQKVKFDIFEKIDVNGDKAHPLWKYLK 129 >gb|AAB21327.2| phospholipid hydroperoxide glutathione peroxidase [Sus scrofa] Length=155 Score = 125 bits (315), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 61/111 (55%), Positives = 80/111 (72%), Gaps = 6/111 (5%) Query 8 FTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILAFPCN 67 F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+ILAFPCN Sbjct 2 FSAKDIDGHMVNLDKYRGYVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCN 61 Query 68 QFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 QFG+ QEPGSDAEIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 62 QFGR------QEPGSDAEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 106 >gb|ACF35507.1| phospholipid-hydroperoxide glutathione peroxidase [Dermacentor variabilis] Length=169 Score = 125 bits (315), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 84/116 (72%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y F IDG+E+ ++ YKG+V + VNVAS+ G T NY QL L +Y + +GL+IL Sbjct 13 SIYDFAAVDIDGNEVSLDKYKGHVALIVNVASKUGKTNKNYVQLVELHEKYAESEGLRIL 72 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++A+IKKF K+NV+F +FSKI+VNG A P+W+++K Sbjct 73 AFPCNQFG------GQEPGTEADIKKFVEKYNVRFDMFSKINVNGDKAHPLWKFLK 122 >gb|ABC25027.1| phospholipid hydroperoxide glutathione peroxidase [Hydra vulgaris] Length=168 Score = 125 bits (314), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 62/115 (54%), Positives = 81/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F KSIDG++I + YKG V + VNVAS+ GLT+ NY QL L +Y +KGL+ILA Sbjct 11 SIFEFQAKSIDGEDISLSKYKGFVTLIVNVASKUGLTELNYAQLADLHTKYAEKGLRILA 70 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG QEPG+D EIK+FA + LFSKIDVNG ADP+++Y+K Sbjct 71 FPCNQFG------NQEPGTDLEIKEFALARGAHYDLFSKIDVNGDKADPLYKYLK 119 >gb|AAO86704.1| phospholipid hydroperoxide glutathione peroxidase A [Danio rerio] Length=163 Score = 124 bits (312), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 54/116 (47%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT IDG+E+ +E Y+G V++ NVAS+ G T NY+Q + +Y ++GL+IL Sbjct 5 KSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRIL 64 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP NQFG+ QEPG++++IK+FA +N +F +FSKIDVNG A P+W+++K Sbjct 65 AFPSNQFGR------QEPGTNSQIKEFAKSYNAEFDMFSKIDVNGDGAHPLWKWLK 114 >gb|ABC25026.1| mitochondrial phospholipid hydroperoxide glutathione peroxidase [Hydra vulgaris] Length=190 Score = 125 bits (314), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 62/115 (54%), Positives = 81/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F KSIDG++I + YKG V + VNVAS+ GLT+ NY QL L +Y +KGL+ILA Sbjct 33 SIFEFQAKSIDGEDISLSKYKGFVTLIVNVASKUGLTELNYAQLADLHTKYAEKGLRILA 92 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG QEPG+D EIK+FA + LFSKIDVNG ADP+++Y+K Sbjct 93 FPCNQFG------NQEPGTDLEIKEFALARGAHYDLFSKIDVNGDKADPLYKYLK 141 >sp|Q32QL6.2|GPX4_CALJA RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor gb|AAY33855.1| phospholipid-hydroperoxide glutathione peroxidase [Callithrix jacchus] Length=197 Score = 125 bits (315), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHTVNLDKYRGFVCIVTNVASQUGKTQVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >ref|NP_001007283.2| glutathione peroxidase 4 precursor [Danio rerio] Length=186 Score = 125 bits (313), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 54/116 (47%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT IDG+E+ +E Y+G V++ NVAS+ G T NY+Q + +Y ++GL+IL Sbjct 28 KSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRIL 87 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP NQFG+ QEPG++++IK+FA +N +F +FSKIDVNG A P+W+++K Sbjct 88 AFPSNQFGR------QEPGTNSQIKEFAKSYNAEFDMFSKIDVNGDGAHPLWKWLK 137 >gb|ABW76146.1| glutathione peroxidase 4a [Danio rerio] Length=186 Score = 125 bits (313), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 54/116 (47%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT IDG+E+ +E Y+G V++ NVAS+ G T NY+Q + +Y ++GL+IL Sbjct 28 KSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRIL 87 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP NQFG+ QEPG++++IK+FA +N +F +FSKIDVNG A P+W+++K Sbjct 88 AFPSNQFGR------QEPGTNSQIKEFAKSYNAEFDMFSKIDVNGDGAHPLWKWLK 137 >pdb|2OBI|A Chain A, Crystal Structure Of The Selenocysteine To Cysteine Mutant Of Human Phospholipid Hydroperoxide Glutathione Peroxidase (Gpx4) Length=183 Score = 125 bits (313), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 25 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQCGKTEVNYTQLVDLHARYAECGLRIL 84 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 85 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 134 >ref|NP_001120347.1| glutathione peroxidase 4 precursor [Xenopus (Silurana) tropicalis] gb|AAI60982.1| LOC100145414 protein [Xenopus (Silurana) tropicalis] Length=191 Score = 125 bits (313), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 54/116 (47%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT IDG+E+ +E Y+G V++ NVAS+ G T NY+Q + +Y ++GL+IL Sbjct 33 KSIYEFTATDIDGNEVSLEKYRGKVVIITNVASKUGKTPVNYSQFAEMHAKYSERGLRIL 92 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP NQFG+ QEPG++++IK+FA +N +F +FSKIDVNG A P+W+++K Sbjct 93 AFPSNQFGR------QEPGTNSQIKEFAKSYNAEFDMFSKIDVNGDGAHPLWKWLK 142 >ref|NP_002076.2| phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform A precursor [Homo sapiens] sp|P36969.3|GPX4_HUMAN RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor sp|Q4AEH2.2|GPX4_PONPY RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor gb|AAC03239.1| GSHH_HUMAN [Homo sapiens] gb|AAC32261.1| selenium-dependent phospholipid hydroperoxide glutathione peroxidase [Homo sapiens] gb|AAP72965.1| glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] dbj|BAE17018.1| glutathione peroxidase 4 [Pongo pygmaeus] Length=197 Score = 125 bits (313), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >emb|CAA50793.1| phospholipid hydroperoxide glutathione peroxidase [Homo sapiens] gb|AAH11836.1| Glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] gb|AAH39849.1| Glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] gb|AAH21567.1| Glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] gb|AAH22071.1| Glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] gb|AAH32695.3| GPX4 protein [Homo sapiens] Length=197 Score = 125 bits (313), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+XG T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >ref|XP_003340790.1| PREDICTED: LOW QUALITY PROTEIN: phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like [Monodelphis domestica] Length=197 Score = 125 bits (313), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ YKG V + NVAS+XG T NYTQL L +Y + GL+IL Sbjct 39 RSMHDFSAKDIDGRLVSLDKYKGYVCIVTNVASQXGKTDVNYTQLVDLHARYAENGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+AEI++FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSNAEIREFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 148 >ref|NP_001112361.1| glutathione peroxidase 4 precursor [Macaca mulatta] Length=197 Score = 125 bits (313), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >ref|NP_001034936.1| phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform B precursor [Homo sapiens] Length=227 Score = 125 bits (315), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >pdb|2GS3|A Chain A, Crystal Structure Of The Selenocysteine To Glycine Mutant Of Human Glutathione Peroxidase 4(Gpx4) Length=185 Score = 124 bits (312), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 27 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQGGKTEVNYTQLVDLHARYAECGLRIL 86 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 87 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 136 >gb|ABD75380.1| phospholipid hydroperoxide glutathione peroxidase [Bufo gargarizans] Length=187 Score = 124 bits (312), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 80/116 (69%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 + +Y F+ IDG+ + +E Y+G V + VNVAS+ G T NYTQL L +Y + GL+IL Sbjct 29 KTIYDFSATDIDGNAVSLEKYRGFVCIIVNVASKUGKTPVNYTQLVNLHAKYAEAGLRIL 88 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPG +++IK FA+ + V+F +FSKIDVNG A P+W++MK Sbjct 89 GFPCNQFGK------QEPGDESQIKDFAASYKVEFDMFSKIDVNGDGAHPLWKWMK 138 >sp|Q4AEG9.2|GPX4_CEBAP RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor dbj|BAE17021.1| glutathione peroxidase 4 [Cebus apella] Length=197 Score = 124 bits (312), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 60/115 (52%), Positives = 82/115 (71%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+ILA Sbjct 40 SMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILA 99 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 100 FPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >gb|AAH46163.1| Glutathione peroxidase 4 (phospholipid hydroperoxidase) [Homo sapiens] Length=197 Score = 124 bits (312), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+XG T+ NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQXGKTEVNYTQLVDLHVRYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >ref|XP_003429587.1| PREDICTED: LOW QUALITY PROTEIN: phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like [Ornithorhynchus anatinus] Length=187 Score = 124 bits (310), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 58/115 (50%), Positives = 83/115 (72%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F+ + IDG + +E Y+G V + NVAS+XG T+ NYTQL L QY +GL+IL Sbjct 30 SIYEFSAEDIDGKLVSLEKYRGKVCIITNVASKXGKTEVNYTQLVDLHAQYAGQGLRILG 89 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG+ QEPG+++EIK+FA+ +NVKF +FSK+ VNG A P+W+++K Sbjct 90 FPCNQFGR------QEPGTNSEIKEFAAGYNVKFDMFSKVCVNGDEAHPLWKWLK 138 >ref|NP_001177287.1| glutathione peroxidase_like protein e [Ciona intestinalis] Length=203 Score = 124 bits (311), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 84/116 (72%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F I G+ + ++ YKGNV + VNVA++ GLTK+NYTQL++L +Y GL+ILA Sbjct 45 SIYEFNALDITGNNVSLDKYKGNVCIIVNVATQUGLTKSNYTQLQSLYEKYSKDGLRILA 104 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG QEP S+AEI KFA FNV+F +F+KIDVNG +A P+++Y+K Sbjct 105 FPCNQFG------NQEPKSNAEILKFAKDTFNVQFDMFAKIDVNGENAIPLYKYLK 154 >gb|ACN78879.1| glutathione peroxidase 4 [Anguilla japonica] Length=186 Score = 123 bits (309), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 56/116 (48%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 + +Y F+ K IDG+E+ +E Y+G + + NVAS+ G T NY+Q + +Y ++GL+IL Sbjct 28 KTIYEFSAKDIDGNEVSLEKYRGFLCIITNVASKUGKTPVNYSQFAQMHAKYAERGLRIL 87 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP NQFGK QEPG++ +IKKFA +N +F LFSKIDVNG A P+W+++K Sbjct 88 AFPSNQFGK------QEPGTEEQIKKFAQSYNAEFDLFSKIDVNGPDAHPLWKWLK 137 >emb|CAD61277.1| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=170 Score = 122 bits (307), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 12 RSMHEFSAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 121 >ref|NP_001034937.1| phospholipid hydroperoxide glutathione peroxidase, mitochondrial isoform C precursor [Homo sapiens] Length=234 Score = 124 bits (312), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 76 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 135 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 136 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 185 >ref|NP_001139295.1| glutathione peroxidase 4 [Pan troglodytes] Length=234 Score = 124 bits (312), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+IL Sbjct 76 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 135 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 136 AFPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 185 >gb|ABK23808.1| unknown [Picea sitchensis] Length=246 Score = 124 bits (312), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 59/117 (50%), Positives = 85/117 (73%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++V+ FT K IDG E+P+ YKG V++AVNVAS+ GLT NYT+L L +Y+ +G +IL Sbjct 86 KSVHDFTVKDIDGKEVPLSKYKGKVLLAVNVASKCGLTTGNYTELSHLYEKYKTQGFEIL 145 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG + EIK+FA ++F +F +F K+DVNG + P+++++K Sbjct 146 AFPCNQFG------GQEPGKNTEIKEFACTRFKAEFPIFDKVDVNGPNTAPVYKFLK 196 >gb|AAC15833.1| phospholipid hydroperoxide glutathione peroxidase [Mus musculus] emb|CAB42657.2| phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAC06508.1| non-mitochondrial phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAC06511.1| non-mitochondrial phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAE35761.1| unnamed protein product [Mus musculus] dbj|BAE35833.1| unnamed protein product [Mus musculus] dbj|BAE40012.1| unnamed protein product [Mus musculus] gb|AAI06148.1| Gpx4 protein [Mus musculus] Length=170 Score = 122 bits (307), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 12 RSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 121 >gb|AAH83137.2| Gpx4 protein [Mus musculus] Length=174 Score = 122 bits (306), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 16 RSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 75 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 76 AFPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 125 >gb|AAA41842.2| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=170 Score = 122 bits (306), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 12 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 121 >emb|CAA57996.1| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] prf||2124383A phospholipid hydroperoxide glutathione peroxidase Length=170 Score = 122 bits (306), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+XG T NYTQL L +Y + GL+IL Sbjct 12 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQXGKTDVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 121 >gb|AAC52503.2| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] emb|CAD61276.1| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=197 Score = 123 bits (308), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 148 >dbj|BAA92142.1| phospholipid hydroperoxide glutathione peroxidase [Cavia porcellus] Length=170 Score = 122 bits (306), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 12 RSMHEFATKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 72 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 121 >gb|ADI56239.1| glutathione peroxidase [Hydra vulgaris] Length=167 Score = 122 bits (306), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 62/115 (54%), Positives = 80/115 (70%), Gaps = 7/115 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F KSIDG++I + YKG V + VNVAS+ GLT+ NY QL L +Y +KGL+ILA Sbjct 11 SIFEFQAKSIDGEDISLSKYKGFVTLIVNVASK-GLTELNYAQLADLHTKYAEKGLRILA 69 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG QEPG+D EIK FA + LFSKIDVNG ADP+++Y+K Sbjct 70 FPCNQFG------NQEPGTDLEIKAFALARGAHYDLFSKIDVNGDKADPLYKYLK 118 >ref|NP_032188.3| phospholipid hydroperoxide glutathione peroxidase, nuclear isoform 2 precursor [Mus musculus] sp|O70325.4|GPX41_MOUSE RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor gb|AAC15832.1| phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAC06507.1| mitochondrial phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAC55251.1| unnamed protein product [Mus musculus] Length=197 Score = 123 bits (308), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 39 RSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 148 >gb|ACR33821.1| glutathione peroxidase 4a [Cyprinus carpio] Length=166 Score = 122 bits (305), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 53/116 (46%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y F+ IDG+E+ +E Y+G V++ NVAS+ G T NY+Q + +Y ++GL IL Sbjct 12 KSIYEFSATDIDGNEVSLEKYRGRVVIITNVASKUGKTPVNYSQFAEMHAKYTERGLSIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFP +QFG QEPG++++IK+FA+ +N +F +FSKIDVNG SA P+W+++K Sbjct 72 AFPSHQFGH------QEPGTNSQIKEFANSYNAQFDMFSKIDVNGDSAHPLWKWLK 121 >gb|ABO38818.2| phospholipid hydroperoxide glutathione peroxidase [Thunnus maccoyii] Length=186 Score = 122 bits (307), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 54/115 (47%), Positives = 81/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F+ IDG+ + +E Y+GNV++ NVAS+ G T NY+Q + +Y ++GL ILA Sbjct 29 SIYDFSATDIDGNLVSLEKYRGNVVIITNVASKUGKTPVNYSQFTQMHAKYAERGLHILA 88 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FP NQFG QEPG++ +IK+FA +N +F +FSKIDVNG++A P+W++MK Sbjct 89 FPSNQFGN------QEPGNETQIKQFAQSYNAQFDMFSKIDVNGANAHPLWKWMK 137 >gb|AEG78385.1| phospholipid hydroperoxide glutathione peroxidase [Epinephelus coioides] Length=191 Score = 122 bits (307), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 55/115 (48%), Positives = 83/115 (72%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F+ IDG+ + +E Y+GNV++ NVAS+XG T+ NY+Q + +Y ++GL ILA Sbjct 34 SIYDFSALDIDGNLVSLEKYRGNVVIITNVASKXGKTQVNYSQFAEMHAKYAERGLHILA 93 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FP NQFG QEPG++A+IK FA +N +F +FSK+DVNG+SA P+W+++K Sbjct 94 FPSNQFGN------QEPGTEAQIKNFAQSYNAQFDIFSKVDVNGASALPLWKWLK 142 >ref|NP_058861.3| phospholipid hydroperoxide glutathione peroxidase, nuclear isoform A precursor [Rattus norvegicus] sp|P36970.3|GPX41_RAT RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor Length=197 Score = 122 bits (307), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 39 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 99 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 148 >dbj|BAA22780.1| phospholipid hydroperoxide glutathione peroxidase [Mus musculus] Length=197 Score = 122 bits (306), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 59/115 (51%), Positives = 82/115 (71%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F+ K IDG + ++ Y+G V + NVAS+XG T NYTQL L +Y + GL+ILA Sbjct 40 SMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQXGKTDVNYTQLVDLHARYAECGLRILA 99 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 100 FPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 148 >ref|YP_003369419.1| glutathione peroxidase [Pirellula staleyi DSM 6068] gb|ADB15559.1| Glutathione peroxidase [Pirellula staleyi DSM 6068] Length=193 Score = 122 bits (306), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 63/111 (57%), Positives = 80/111 (72%), Gaps = 8/111 (7%) Query 8 FTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILAFPCN 67 FT KSI G E+ + YKG V+V VNVAS GLT Y +L+AL +Y DKGL +L FPCN Sbjct 37 FTVKSIAGKEVDLAKYKGKVLVVVNVASACGLTP-QYEELQALHTKYADKGLAVLGFPCN 95 Query 68 QFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYM 117 QFGK QEPGSDAEI +F S++NV F +FSKIDVNG +A+P+++Y+ Sbjct 96 QFGK------QEPGSDAEIAEFCKSEYNVSFDMFSKIDVNGETANPLYKYL 140 >ref|NP_001036999.1| glutathione peroxidase [Bombyx mori] dbj|BAE07196.1| glutathione peroxidase [Bombyx mori] Length=199 Score = 122 bits (306), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 62/119 (52%), Positives = 82/119 (69%), Gaps = 7/119 (6%) Query 1 AYQNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQY-RDKGL 59 A +++ FT K+I G+++ ++ YKG+V + VNVAS+ GLT NY QL L QY KGL Sbjct 40 AATSIHEFTVKNIKGEDVKLDVYKGHVCIIVNVASQCGLTANNYKQLNELYEQYGESKGL 99 Query 60 KILAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 +ILAFPCNQF GQEPG+ EI FAS+ VKF LF K+DVNG +A P+W+Y+K Sbjct 100 RILAFPCNQFA------GQEPGNPEEIVCFASERKVKFDLFEKVDVNGDNASPLWKYLK 152 >gb|EFN75696.1| Probable phospholipid hydroperoxide glutathione peroxidase [Harpegnathos saltator] Length=168 Score = 121 bits (303), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 61/116 (53%), Positives = 76/116 (66%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 ++Y FT SI G+E+P+ YKG+V + VNVAS+ GLT NY +L L +Y + KGL+IL Sbjct 12 SIYDFTANSIRGEEVPLSKYKGHVCLIVNVASKCGLTATNYKELNELYDEYAESKGLRIL 71 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQF GQEPG EI FA + VKF LF KIDVNG P+W Y+K Sbjct 72 AFPCNQF------NGQEPGDSEEICSFADRHKVKFDLFEKIDVNGDKTHPLWSYLK 121 >sp|Q4AEH0.2|GPX4_MACFU RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor dbj|BAE17020.1| glutathione peroxidase 4 [Macaca fuscata] Length=197 Score = 122 bits (305), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 83/116 (72%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + G++IL Sbjct 39 RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGVRIL 98 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEPGS+ +IK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 99 AFPCNQFGK------QEPGSNEKIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >sp|Q4AEH1.2|GPX4_HYLLA RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Short=PHGPx; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4; Flags: Precursor dbj|BAE17019.1| glutathione peroxidase 4 [Hylobates lar] Length=197 Score = 122 bits (305), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 58/115 (50%), Positives = 81/115 (70%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 +++ F+ K +DG + ++ Y+G V + NVAS+ G T+ NYTQL L +Y + GL+ LA Sbjct 40 SMHEFSAKVLDGHTVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRFLA 99 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQFGK QEPGS+ EIK+FA+ +NVKF +FSKI VNG A P+W++MK Sbjct 100 FPCNQFGK------QEPGSNEEIKEFAAGYNVKFDMFSKICVNGDDAHPLWKWMK 148 >ref|XP_969867.1| PREDICTED: similar to glutathione peroxidase [Tribolium castaneum] gb|EFA01369.1| hypothetical protein TcasGA2_TC010354 [Tribolium castaneum] Length=198 Score = 122 bits (305), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 80/116 (69%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQ-LEALDRQYRDKGLKIL 62 +Y FT K+I+G+EI +E YKG+V + VNVAS+ G TK+NY Q +E D+ +KGL+IL Sbjct 42 TIYEFTAKTIEGEEISLEKYKGHVCIIVNVASKCGHTKSNYEQFVELYDKYSEEKGLRIL 101 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG +I +F NVKF +F KI VNG A P+W+++K Sbjct 102 AFPCNQFG------GQEPGDSEKICEFVKARNVKFDMFEKIKVNGKDAHPLWKFLK 151 >ref|XP_002429001.1| phospholipid hydroperoxide glutathione peroxidase, putative [Pediculus humanus corporis] gb|EEB16263.1| phospholipid hydroperoxide glutathione peroxidase, putative [Pediculus humanus corporis] Length=172 Score = 120 bits (302), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 62/117 (53%), Positives = 77/117 (66%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 Q+VY FT G+ + +E YKG+V++ VNVAS GLT NY +L L ++ D KGL+I Sbjct 15 QSVYDFTVNDSSGNPVSLEKYKGHVLLIVNVASRCGLTATNYKELVELHDKFHDSKGLRI 74 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQFG GQEPG+D EI FA K N F FSKI VNG A P+W+Y+K Sbjct 75 LAFPCNQFG------GQEPGTDEEIVCFAKKKNAHFDFFSKIKVNGDDASPLWKYLK 125 >gb|ABK58680.1| PHGPx isoform 2 [Clonorchis sinensis] Length=181 Score = 120 bits (302), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 59/116 (51%), Positives = 77/116 (66%), Gaps = 7/116 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 Q++Y F IDG ++ M Y G V + VNVASE LT NY QL+AL +Y + GL++L Sbjct 21 QSIYDFNVTDIDGKDVDMHRYSGKVCIIVNVASEUALTGTNYVQLQALYTKYYEHGLRVL 80 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYM 117 AFPCNQFG GQEPG+DA+IK+ S +NV F LF K+DVNG A P++ Y+ Sbjct 81 AFPCNQFG------GQEPGTDAQIKEHVQSAYNVTFDLFHKVDVNGDDAIPLYNYL 130 >ref|XP_002272606.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial isoform 1 [Vitis vinifera] ref|XP_003631418.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial isoform 2 [Vitis vinifera] emb|CBI34679.3| unnamed protein product [Vitis vinifera] Length=168 Score = 120 bits (301), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 58/117 (50%), Positives = 85/117 (73%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 Q+V+SFT K G+++ + YKG ++ VNVAS+ GLT +NYT+L L +Y+D+GL+IL Sbjct 8 QSVHSFTVKDARGNDVDLSIYKGKALLIVNVASQCGLTNSNYTELHQLYEKYKDQGLEIL 67 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPGS+ EI+KF ++F ++ +F KIDVNG SA P+++++K Sbjct 68 AFPCNQFG------AQEPGSNEEIEKFVCTRFKAEYPIFDKIDVNGDSAAPLYKFLK 118 >ref|XP_002979231.1| hypothetical protein SELMODRAFT_228619 [Selaginella moellendorffii] gb|EFJ19639.1| hypothetical protein SELMODRAFT_228619 [Selaginella moellendorffii] Length=245 Score = 122 bits (306), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 55/117 (47%), Positives = 87/117 (74%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ FT K+IDG +I + TYKG V++ VN+AS+ GLT NY +L + ++Y+D+G ++L Sbjct 88 KSIHDFTVKNIDGKDIDLSTYKGKVLLVVNIASQCGLTSGNYKELVEVHKKYKDQGFEVL 147 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPGS+ EIK+FA +++ +F +F K+DVNG S P+++++K Sbjct 148 AFPCNQFG------GQEPGSNEEIKQFACTRYKAEFPIFDKVDVNGPSTAPVYQFLK 198 >gb|AEI91049.1| glutathione peroxidase 4 variant 1 [Seriola lalandi] Length=186 Score = 120 bits (302), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 51/115 (44%), Positives = 84/115 (73%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F+ IDG+E+ ++ Y+G+V++ NVAS+ G T NY+Q + +Y ++GL+ILA Sbjct 29 SIYDFSATDIDGNEVSLDRYRGDVVIITNVASKUGKTPVNYSQFAQMHAKYAERGLRILA 88 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FP NQFG QEPG++++IK+FA +N +F +FSKI+VNG++A P+W+++K Sbjct 89 FPSNQFGN------QEPGNESQIKQFAQSYNAQFDMFSKINVNGANAHPLWKWLK 137 >emb|CAM34513.1| putative phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor [Cotesia congregata] Length=168 Score = 120 bits (300), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 60/117 (51%), Positives = 79/117 (68%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEAL-DRQYRDKGLKI 61 ++V+ F KSI G+++P+E YKG+V++ VNVAS+ GLT NY +L L D+ GL+I Sbjct 11 KSVHDFEAKSIKGEDVPLEKYKGHVLLIVNVASKCGLTATNYKELNELYDQLAESHGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF GQEPG EI FA + VKF LF KIDVNG + P+W+Y+K Sbjct 71 LAFPCNQF------NGQEPGDSDEICSFADRQKVKFDLFEKIDVNGETTHPLWKYLK 121 >gb|ADI58543.1| glutathione peroxidase 1 [Brassica napus] gb|ADI58544.1| glutathione peroxidase 1 [Brassica napus] Length=236 Score = 122 bits (305), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 58/119 (49%), Positives = 85/119 (71%), Gaps = 7/119 (6%) Query 1 AYQNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLK 60 A + V+ FT K IDG+++ + YKG V++ VNVAS GLT +NY++L L +Y+ +G + Sbjct 75 AEKTVHEFTVKDIDGNDVSLNKYKGKVMLIVNVASRCGLTSSNYSELSHLYEKYKSQGFE 134 Query 61 ILAFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 ILAFPCNQFG GQEPGS+ EIK+FA ++F +F +F K+DVNG S P+++++K Sbjct 135 ILAFPCNQFG------GQEPGSNPEIKQFACTRFKAEFPIFDKVDVNGPSTAPIYQFLK 187 >emb|CAD61278.1| phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=253 Score = 122 bits (306), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 95 RSMHEFSAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 154 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 155 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 204 >emb|CAL59721.1| glutathione peroxidase [Medicago sativa] Length=234 Score = 122 bits (305), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 58/117 (50%), Positives = 83/117 (71%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT K ID ++P+ +KG V++ VNVAS GLT +NYT+L L ++DKGL+IL Sbjct 76 KSIYDFTVKDIDKKDVPLSKFKGKVLLIVNVASRCGLTSSNYTELSHLYENFKDKGLEIL 135 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPGS+ EIKKFA ++F +F +F K+DVNG P+++++K Sbjct 136 AFPCNQFGM------QEPGSNEEIKKFACTRFKAEFPIFDKVDVNGPFTAPVYQFLK 186 >gb|AEI91050.1| glutathione peroxidase 4 variant 2 [Seriola lalandi] Length=191 Score = 120 bits (301), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 51/115 (44%), Positives = 84/115 (73%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y F+ IDG+E+ ++ Y+G+V++ NVAS+ G T NY+Q + +Y ++GL+ILA Sbjct 34 SIYDFSATDIDGNEVSLDRYRGDVVIITNVASKUGKTPVNYSQFAQMHAKYAERGLRILA 93 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FP NQFG QEPG++++IK+FA +N +F +FSKI+VNG++A P+W+++K Sbjct 94 FPSNQFGN------QEPGNESQIKQFAQSYNAQFDMFSKINVNGANAHPLWKWLK 142 >dbj|BAJ33870.1| unnamed protein product [Thellungiella halophila] Length=235 Score = 121 bits (304), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 58/119 (49%), Positives = 85/119 (71%), Gaps = 7/119 (6%) Query 1 AYQNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLK 60 A + V+ FT K IDG+++ + +KG V++ VNVAS GLT +NY++L L +Y+ +G + Sbjct 74 AEKTVHDFTVKDIDGNDVSLNKFKGKVMLIVNVASRCGLTSSNYSELSHLYEKYKSQGFE 133 Query 61 ILAFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 ILAFPCNQFG GQEPGS+ EIK+FA ++F +F +F K+DVNG S P++E++K Sbjct 134 ILAFPCNQFG------GQEPGSNPEIKQFACTRFKAEFPIFDKVDVNGPSTAPIYEFLK 186 >sp|Q91XR9.3|GPX42_MOUSE RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, nuclear; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4 gb|AAK74112.1|AF274027_1 phospholipid hydroperoxide glutathione peroxidase [Mus musculus] Length=253 Score = 122 bits (305), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 95 RSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 154 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 155 AFPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 204 >ref|XP_003427378.1| PREDICTED: probable phospholipid hydroperoxide glutathione peroxidase-like [Nasonia vitripennis] Length=194 Score = 120 bits (301), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 60/116 (52%), Positives = 80/116 (69%), Gaps = 7/116 (6%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKIL 62 +VY F +I G+E+P++ YKG+V++ VNVAS+ GLT NY +L L +Y D KGL+IL Sbjct 38 SVYDFVVNNIKGEEVPLDKYKGHVLLIVNVASKCGLTATNYKELNELYDKYADSKGLRIL 97 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQF GQEPG+ +I FA + VKF LF KIDVNG + P+W+Y+K Sbjct 98 AFPCNQF------NGQEPGTPEDICSFADRQKVKFDLFEKIDVNGDNTHPLWKYLK 147 >ref|NP_001032830.2| phospholipid hydroperoxide glutathione peroxidase, nuclear isoform 1 [Mus musculus] dbj|BAC06509.1| nuclear phospholipid hydroperoxide glutathione peroxidase [Mus musculus] dbj|BAC87835.1| nucleolar phospholipid hydroperoxide glutathione peroxidase [Mus musculus] Length=253 Score = 122 bits (305), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 58/116 (50%), Positives = 82/116 (71%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F+ K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 95 RSMHEFSAKDIDGHMVCLDKYRGFVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 154 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NVKF ++SKI VNG A P+W++MK Sbjct 155 AFPCNQFGR------QEPGSNQEIKEFAAGYNVKFDMYSKICVNGDDAHPLWKWMK 204 >ref|NP_001034938.1| phospholipid hydroperoxide glutathione peroxidase, nuclear isoform B [Rattus norvegicus] sp|Q91XR8.3|GPX42_RAT RecName: Full=Phospholipid hydroperoxide glutathione peroxidase, nuclear; AltName: Full=Glutathione peroxidase 4; Short=GPx-4; Short=GSHPx-4 Length=253 Score = 122 bits (305), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 95 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 154 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 155 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 204 >ref|NP_001171492.1| glutathione peroxidase-like 1 [Apis mellifera] ref|NP_001171493.1| glutathione peroxidase-like 1 [Apis mellifera] gb|AAP93585.1| putative thioredoxin perxidase [Apis mellifera ligustica] Length=168 Score = 119 bits (298), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 61/117 (52%), Positives = 81/117 (69%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 +++Y FT KSI G+++ + YKG+V + VNVAS+ GLT NY +L L +Y + KGL+I Sbjct 11 KSIYDFTAKSIKGEDVFLSKYKGHVCLIVNVASKCGLTATNYKELNELYDEYAESKGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF GQEPG+ +I FA + VKF LF KIDVNG SA P+W+Y+K Sbjct 71 LAFPCNQF------NGQEPGNSEDICNFADRQKVKFDLFEKIDVNGDSAHPLWKYLK 121 >emb|CAJ43709.1| glutathion peroxidase [Plantago major] Length=168 Score = 119 bits (298), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 55/117 (47%), Positives = 86/117 (74%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 Q+++ FT K GD++ + YKG V++ VNVAS+ GLT +NYT+L L ++Y+D+GL+IL Sbjct 8 QSIHDFTVKDAKGDDVDLSIYKGKVLLIVNVASQCGLTNSNYTELTTLYQKYKDQGLEIL 67 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPGS+ EI+ F ++F ++ +F K+DVNG++A P+++++K Sbjct 68 AFPCNQFG------SQEPGSNEEIQNFVCTRFKAEYPIFDKVDVNGATAAPIYKFLK 118 >ref|XP_003588874.1| Glutathione peroxidase [Medicago truncatula] gb|AES59125.1| Glutathione peroxidase [Medicago truncatula] Length=236 Score = 121 bits (303), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 57/117 (49%), Positives = 83/117 (71%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT K ID ++P+ +KG V++ VNVAS GLT +NYT+L L ++DKGL++L Sbjct 77 KSIYDFTVKDIDKKDVPLSKFKGKVLLIVNVASRCGLTSSNYTELSHLYENFKDKGLEVL 136 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPGS+ EIKKFA ++F +F +F K+DVNG P+++++K Sbjct 137 AFPCNQFGM------QEPGSNEEIKKFACTRFKAEFPIFDKVDVNGPFTAPVYQFLK 187 >ref|XP_003439917.1| PREDICTED: LOW QUALITY PROTEIN: phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like [Oreochromis niloticus] Length=186 Score = 119 bits (299), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 54/115 (47%), Positives = 82/115 (71%), Gaps = 6/115 (5%) Query 4 NVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKILA 63 ++Y+F+ IDG+ + +E Y+GNV++ NVAS+XG T NY+Q L +Y ++GL ILA Sbjct 29 SIYNFSATDIDGNVVSLEKYRGNVVIITNVASKXGKTPVNYSQFTQLHAKYAERGLSILA 88 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FP NQFG QEPG++ +IK+FA F+ +F +FSKI+VNG +A P+W+++K Sbjct 89 FPSNQFGN------QEPGNETQIKQFADTFSARFDMFSKIEVNGQNAHPLWKWLK 137 >ref|NP_001177284.1| glutathione peroxidase_like protein d precursor [Ciona intestinalis] Length=197 Score = 120 bits (300), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 61/117 (52%), Positives = 83/117 (71%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT ID E+ + YKG+V + VNVASE G TK NY QL+ L +Y +GLKIL Sbjct 36 KDIYGFTVNDIDDQEVSLSKYKGHVCIIVNVASEUGFTKVNYEQLQQLYGKYSQQGLKIL 95 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASK-FNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFGK QEP +A+IKKFA++ + V F LFSKI+VNG +A P+++++K Sbjct 96 AFPCNQFGK------QEPKPNADIKKFATENYGVTFDLFSKINVNGDNAIPLYKFLK 146 >gb|ACJ84092.1| unknown [Medicago truncatula] Length=236 Score = 120 bits (302), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 57/117 (49%), Positives = 83/117 (71%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 +++Y FT K ID ++P+ +KG V++ VNVAS GLT +NYT+L L ++DKGL++L Sbjct 77 KSIYDFTVKDIDEKDVPLSKFKGKVLLIVNVASRCGLTSSNYTELSHLYENFKDKGLEVL 136 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG QEPGS+ EIKKFA ++F +F +F K+DVNG P+++++K Sbjct 137 AFPCNQFGM------QEPGSNEEIKKFACTRFKAEFPIFDKVDVNGPFTAPVYQFLK 187 >gb|AAK74113.1|AF274028_1 phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=257 Score = 121 bits (304), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 57/116 (49%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 102 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 161 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SKI VNG A P+W++MK Sbjct 162 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKICVNGDDAHPLWKWMK 211 >ref|XP_002990305.1| hypothetical protein SELMODRAFT_16028 [Selaginella moellendorffii] gb|EFJ08574.1| hypothetical protein SELMODRAFT_16028 [Selaginella moellendorffii] Length=157 Score = 118 bits (296), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 53/117 (45%), Positives = 86/117 (74%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ FT K+IDG +I + YKG V++ VN+AS+ GLT NY +L + ++Y+D+G ++L Sbjct 7 KSIHDFTVKNIDGKDIDLSMYKGKVLLVVNIASQCGLTSGNYKELVEVHKKYKDQGFEVL 66 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFA-SKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG GQEPG++ EIK+FA +++ +F +F K+DVNG S P+++++K Sbjct 67 AFPCNQFG------GQEPGTNEEIKQFACTRYKAEFPIFDKVDVNGPSTAPVYQFLK 117 >dbj|BAC87836.1| nucleolar phospholipid hydroperoxide glutathione peroxidase [Rattus norvegicus] Length=253 Score = 121 bits (303), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 56/116 (48%), Positives = 81/116 (70%), Gaps = 6/116 (5%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRDKGLKIL 62 ++++ F K IDG + ++ Y+G V + NVAS+ G T NYTQL L +Y + GL+IL Sbjct 95 RSMHEFAAKDIDGHMVCLDKYRGCVCIVTNVASQUGKTDVNYTQLVDLHARYAECGLRIL 154 Query 63 AFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 AFPCNQFG+ QEPGS+ EIK+FA+ +NV+F ++SK+ VNG A P+W++MK Sbjct 155 AFPCNQFGR------QEPGSNQEIKEFAAGYNVRFDMYSKVCVNGDDAHPLWKWMK 204 >gb|EFN70618.1| Probable phospholipid hydroperoxide glutathione peroxidase [Camponotus floridanus] Length=168 Score = 119 bits (297), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 59/115 (51%), Positives = 78/115 (68%), Gaps = 7/115 (6%) Query 5 VYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKILA 63 +Y FT SI G+E+P+ Y+G+V + VNVAS+ GLT NY +L L +Y + KGL+ILA Sbjct 13 IYDFTANSIKGEEVPLSKYQGHVCLIVNVASKCGLTATNYKELNELYDEYAESKGLRILA 72 Query 64 FPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 FPCNQF GQEPG+ EI FA + V+F LF KIDVNG++ P+W Y+K Sbjct 73 FPCNQF------NGQEPGNSEEICSFADRQKVQFDLFEKIDVNGNNTHPLWAYLK 121 >gb|ACZ66012.1| phospholipid hydroperoxide glutathione peroxidase 1 [Apis cerana cerana] Length=168 Score = 119 bits (297), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 61/117 (52%), Positives = 81/117 (69%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 Q++Y FT KSI G+++ + YKG+V + VNVAS+ GLT NY +L L +Y + KGL+I Sbjct 11 QSIYDFTAKSIKGEDVFLSKYKGHVCLIVNVASKCGLTATNYKELNELYDEYAESKGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF QEPG+ +I FA++ VKF LF KIDVNG SA P+W+Y+K Sbjct 71 LAFPCNQF------NSQEPGNSDDICNFANRQKVKFDLFEKIDVNGDSAHPLWKYLK 121 >gb|ADG21870.1| phospholipid hydroperoxide glutathione peroxidase 1 [Apis cerana cerana] Length=168 Score = 118 bits (296), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 61/117 (52%), Positives = 81/117 (69%), Gaps = 7/117 (6%) Query 3 QNVYSFTHKSIDGDEIPMETYKGNVIVAVNVASEXGLTKANYTQLEALDRQYRD-KGLKI 61 Q++Y FT KSI G+++ + YKG+V + VNVAS+ GLT NY +L L +Y + KGL+I Sbjct 11 QSIYDFTAKSIKGEDVFLSKYKGHVCLIVNVASKCGLTATNYKELNELYDEYAESKGLRI 70 Query 62 LAFPCNQFGKYTCLRGQEPGSDAEIKKFASKFNVKFQLFSKIDVNGSSADPMWEYMK 118 LAFPCNQF QEPG+ +I FA++ VKF LF KIDVNG SA P+W+Y+K Sbjct 71 LAFPCNQF------NSQEPGNSDDICNFANRQKVKFDLFEKIDVNGDSAHPLWKYLK 121 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Jan 11, 2012 4:12 PM Number of letters in database: 1,516,989,569 Number of sequences in database: 16,927,445 Lambda K H 0.322 0.137 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 16927445 Number of Hits to DB: 126375628 Number of extensions: 4207569 Number of successful extensions: 8456 Number of sequences better than 100: 314 Number of HSP's better than 100 without gapping: 0 Number of HSP's gapped: 7875 Number of HSP's successfully gapped: 314 Length of query: 118 Length of database: 5811956865 Length adjustment: 85 Effective length of query: 33 Effective length of database: 4373124040 Effective search space: 144313093320 Effective search space used: 144313093320 T: 11 A: 40 X1: 16 (7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (20.4 bits) S2: 68 (30.8 bits)