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       IUPAC-IUB/GCG Ambiguity Codes
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Legend                                               . (( (( (( (( (( (( (( (( ( .. .. .. .. . (( (( (( ( ... .. .. .. . . .. ) ) ) ) ) ) ) . . . . )) )) )) )) ) ) )) ) ) )) ) .                                          
Structure - - - - - - - - - . . . . . . . . . . . . . ( ( ( ( ( ( ( . . ( ( ( ( . . . ( ( ( ( ( ( ( - - - - - - . . . - - - ( ( - - - - - . . . . . - - - - - - - - - - - - - ) ) . . - - - - - - - ) ) ) ) ) ) ) ) ) ) ) . . . . ) ) ) ) ) ) ) . . . . . . . . . . . . - - - - -  
tr1- - - - - - - - - U C A A U A A U U C A U C G A G G A C G A A U G A A U U A U C A U C C A - - - - - - C A A - - - A C - - - - - A U C A A - - - - - - - - - - - - - G U G C - - - - - - - U G G A U G A U G A U G A U A U G U C C U U C U U A C C U U C U U U - - - - - SP
Human 15kDa AGAGUGAAACAUUCACAAAGAUUUGCGUUAAUGAAGACUACACAG------AAAA--CCU----UUCU-------------AGGGAU---UUGUGUGGAUAGAUACAUACCUUGGCAAAUUUUUGAGU----SP
Rat 15kDa --AAUGUAAUACUUAUAAAGGUUUGCAUUAAUGAGGAUUACACA-------GAA---AACCUUUGUU-----------AAGGGUU-----UGUGUCGAUCUGAUAAUUGGCAAAUUUUUAUUUUUAAAAU--SP
Cow 15kDa ---GAAAUAUUCACACAAAGAUUUGCAUUAAUGAAGACUACACAG------AAAA--CCUU---CCU-------------GAGGAU----UUGUGUGGACUGAUACUUAGCAAACUUUUUGUGCUUUACAU-SP
M.fascicularis 15kDa AGGGUGAAACAUUCACAAAGAUUUGCGUUAAUGAAGACUACACAG------AAAA--CCUU---CCU-------------AAGGAU----UUGUGUGGAUAGAUACAUACCUUGGCAAAUUUUUUGAG----SP
Trout 15kDa CAUGAGAAUGUUCUGGGGAGGCACACAUUAAUGAAGGCCUCACA------GUAAA--CCA----CAGUU------------UGGGA-----UGUGAGACCUGAUGGCCCUGUGUGUUUCUCUG---------SP
Pig 15kDa GGAGUGAAACAGUCGCACAGAUUCGCAUUAAUGAAGACUACACAG------AAAA--CCUU---UUU-------------GAGGAU----UUGUGUGGAUUGAUGUUGACGCAAAUUUUUGUGCUUU-----SP
O.mykiss 15kDa CAUGCAGAUGUUCCGGGGAGGAACACAUUAAUGAAGGCCUCACA------GCAAA--CCA----CAUUU------------UGGGA-----UGUGAGACCAGAUGUCCCUGUGUGUCACUCUG---------SP
Dog 15kDa ---AGAGUAUCUUCACAGAGAUUUGCAUUAAUGAAGACUACACAG------AAAA--CCUU---CAG-------------GAGGAU----UUGUGUGGAUUGAUAUUUAGCAACAAUUUUGUGUUUCACAC-SP
M.auratus 15kDa GAGUGUUUACACUCAUAAAGGUUUGCAUUAAUGAGGAUUACACAG------AAAA--CCUU---UGUU------------AAGGAU----UUGUGUAGAUUGAUAAUCUGGCAGAUUUUUAUGUU-------SP
Mouse 15kDa ---AUUUAAUACUUAUAAAGGUUUGCAUUAAUGAGGAUUACACAG------AAAA--CCUU--UGUU-------------AAGGAC----UUGUGUAGAUUGAUAAUUGGCAAACUUUUUAUUUUAAAAGU-SP
Chimp 15kDa AGAGUGAAACAUUCACAAAGAUUUGCGUUAAUGAAGACUACACAG------AAAA--CCUU---UCU-------------AAGGAU----UUGUGUGGAUAGAUACAUACCUUGGCAAAUUUUUGAGU----SP
M.mulatta 15kDa AGGGUGAAACAUUCACAAAGAUUUGCGUUAAUGAAGACUACACAG------AAAA--CCUU---CCU-------------AAGGAU----UUGUGUGGAUAGAUACAUACCUUGGCAAAUUUUUGAGU----SP
Zebrafish DI1 UGGGUUUUCUUUUUGAACUUGUGACUGUAAAUGAUGCUUACAGGGU-----AAA---AC-----UGU---------------GUGA---ACUGUGUAAACUGAUGAUUCAGUCAUUUGUUCUUA--------SP
Human DI2 CAGAGAUGUGCAGAGUUGACCAGUGUGCGGAUGAUAACUACUGAC------GAAA--GAGUC--AUC------------GACUCA-----GUUAGUGGUUGGAUGUAGUCACAUUAGUUUGCCUCUC-----SP
Zebrafish DI2 -AUUUGGUUCAAUACGGUGUUGGUGUGCACAUGAAAAUCACAGAUG------AA---AUGG---UCCC------------CUGUCC---UGUCUGUGGUUGGAUGAGAGACCACACCUCUCCGUCCUGAU--SP
Mouse DI2 CGGAGAUGUUCAGAGCUCACUGGUGUGCGAAUGAUAACUACUGAC------GAAA--GAGC---UGUCU-----------GCUCA-----GUCUGUGGUUGGAUGUAGUCACACGAGUCUGCCUUUCUGCA-SP
Trout DI2 GGUUUGGGUCGAGACGGGGCUGGUGUGAGAAUGAAAACCACUGAC------UAA---AGGGUU-ACU-----------GACUCU------GUUUGUGGUCGGAUGACAGACCUCACCUCCCUGGCG------SP
O.mykiss DI2 GGUUUGGGUCGAGACGGGGCUGGUGUGAGAAUGAAAACCACUGAC------UAA---AGGGUU-ACU-----------GACUCU------GUUUGUGGUCGGAUGACAGACCUCACCUCCCUGGCG------SP
Chicken DI2 --GGGGUGAAACCUGAAUGCUUGUGUGUUUAUGAAGAGCACUAAC------AAAA--GAGU---AAUUG-----------ACUCA-----GUUGGUGUUCAGAUGCUCUCACACUGGCAUUCCUUUG-----SP
Chicken DI2 --GGGGUGAAACCUGAAUGCUUGUGUGUUUAUGAAGAGCACUAAC------AAAA--GAGU---AAUUG-----------ACUCA-----GUUGGUGUUCAGAUACUCUCACACUGGCAUUCCUCUG-----SP
X.laevis DI3 ------CACUGACUCUGCAGGUGGUUGCUAAUGAAGACCGACUUU------GAAA--UGGUC-UCAC------------GGCCAA----AAACUCGCGUCCGACGUCUCCCCUUCCCUUUCUCA--------SP
X.laevis DI3 -----ACUCCGACUCUGCAGGUGUUUGCAAAUGACGACCGAUUUU------GAAA--UGGUC-UCAC------------GGCCAA----AAACUCGUGUCCGACAUCAACCCCCUUCCUCAAACUACCUGC-SP
Human DI3 ----UUGGGUGCACAGGAGCCCCACUGCUGAUGACGAACUAUCUC------UAAC--UGGU--CUUG-------------ACCAC-----GAGCUAGUUCUGAAUUGCAGGGGCCUCAAAGCAGCA------SP
Salmon DI3 AAGUUACUUUAGGAUACAACUGCUUUUUCCAUGAUGGUUACAGUG------CAA---ACC----UCU--------------GGU------CAUUGUAAUUUGAUGAACUGAAAGCAGUUUUUUGCUAAGU--SP
Rat DI3 ---UUAGGUGCGCUGGAACCCUGGCUGCUGAUGACGAACCGCCU------CUAAC--UGG----GCUUGA-----------CCAC-----GGGUCGGCUCUGAAUUGCAGAGGGGCUCGAAACAGCGCC---SP
Mouse DI3 --UUUGGGUGCGCUGGAGCCCUGGCUGCUGAUGACGAACCGCCU------CUAAC--UGG----GCUUGA-----------CCAC-----GGGUCGGCUCUGAAUUGCAGAGAGGCUCGAAACAGCGCCU--SP
Trout DI3 AAGUUACUUUGGGAUACAACUGCUUUUUCCAUGAUGAUUACAGUG------CAA---ACC----UCU--------------GGU------CAUUGUAAUUUGAUGAACUGAAAGCAGUUUUGUUGCUAAA--SP
M.mulatta DI3 ----UUGGGUGCACAGGAGCCCCACUGCUGAUGACGAACUGUCUC------UAAC--UGGU--CUUG-------------ACCAC-----GAGCUAGUUCUGAAUUGCAGGGGCCUCAAAACAGCA------SP
T.thermophila GPx AUUUUCAAAUAUUGAAAACUAAAAUGUUAAAUGAAAGAUUAUUUUU-----AAA---UUU----GUAA-------------AAA-----AGAAAUAAUUUUGAAAAAAAUAUUAUUUUAGUUAGU-------SP
Zebrafish GPx1 UAAACGUUGCUGAGUUUGGACUUUUACUUCAUGAAGAUGCUCCUG------UAA---ACAUG--CUUG-----------UCUGUC------GGGAGCAGCUGAUGCCCUGCAAAAGUCUAGGCUGAAC----SP
Salmon GPx2 AAAUGCUACUGUGUUCUGAACUUUUAUUAAAUGAAGCCAUCCUUU------GAAAC-CACA---CAUUU-----------UGUGA------GGGGGAUUUUGAUGAAAUAUCAAAAGUCUUAACAUAA----SP
O.fasciatus GPx2 UGCACUAUGGUUGUUCAGCCUGUUUACUCAAUGAAGACACUCCUUU------AA---GC-----CUUUUU------------GUG----AGGGGAGUUUCUGAUGAAGACGUAAAAGACUGACU--------SP
Trout GPx2 --AGGCACGACCACCAGGGAUUACACCCAGAUGAAUGAGCUCCAUG------AA---CGG----UACG-------------CCGA----CAAGGGGCUAGUGAUUCUGGGGGUGCCCUGCAAUCAGUUCG--SP
O.mykiss GPx2 AAAAGCUGCUGUGUUCUGAACUUUUAUUAAAUGAAGGCAUCCAUU------GAA---ACCAA--GCCU----------UUUGUGA-----GAGGGAUGUCUGAUGAAAUGUAAAAGACUUAACAUAAC----SP
Human GPx3 -ACGGACCCCAUGGCAGGGGUGGCGUCUUCAUGAGGGAGGGGCCC------AAA---GCCC---UUGU-------------GGGC-----GGACCUCCCCUGAGCCUGUCUGAGGGGCCAGCCC--------SP
Salmon GPx3 GGGUUGUAGGUCAUUGAGGUGGCAUGUUGUAUGAAGGCGAGGC------UUGAAA--ACAG---UGAUU-----------CUGUGGU-----GCCAAGCCUGAGUUCUAGGGUCCAGGCCAGUCCUUC----SP
Rat GPx3 CAUGUGCUCCAAGUCAGGGGUGGUGUCUCCAUGAAGGAGGGGCCC------GAA---GCCC---UUGU------------GGGC------GGGCCUCCCCUGAGCCCGUCUGUGGUGCCAGCCCUU------SP
Horse GPx3 UACAUUCCCCAUGUCAGGGGUGGCAUCUCCAUGAUGGAGGGGCCC------GAA---GCCC---UGGU------------GGGC------GGACCUCCCCAGAGCCUGUCUGAAGGGCCAGCCCU-------SP
Cow GPx3 ACGUUCCCCGUGUCAGGGGGCGGCAUCGCCAUGAAGGAGGGGCCC------GAA---GCCC---GCGU------------GGGC------GGGCCUCCCUUGAGCCUGUCUGAGGGGCCAGCCU--------SP
Trout GPx3 -----GGUCAUAAAGGAGGUGGCAUGUUGUAUGAAGGUGAGGC------UUGAAA--ACAG---UGAUU-----------CUGUGGU-----GCCAAGCCUGAGUUCUAGGGUCCAGGCCAGUCCUUCAG--SP
C.lupus GPx3 CAUGUUCCCCGUGUCAGGAAUGGCAUCUCCAUGAAGGAGGGGCCC------GAA---GCCC---UCAU------------GGGC------GGACCUCCCCUGAGCCUGUCUGAAGGGCCGGCCCU-------SP
X.tropicalis GPx3 GAGAUCUGAGGGAAUCUAUAAGCUAUCUGUAUGAAGGCCAAGUC-------AAAAA-GCAC---UCAU------------GUGUGG-----GACUUGUCUGGAAACCAGUGCUGGGGCAGAUG---------SP
Dog GPx3 CAUGUUCCCCGUGUCAGGAAUGGCAUCUCCAUGAAGGAGGGGCCC------GAA---GCCC---UCAU------------GGGC------GGACCUCCCCUGAGCCUGUCUGAAGGGCCGGCCCU-------SP
X.laevis GPx3 GAGAUCCAAGGGAAUCUAGAAGCUAUCUGUAUGAAGGCCAAGUC-------AAAAA-GCAU---UCAU------------GUGUGG-----GACUUGGCUGGAAACCAGUGCUGGGGCAGAUG---------SP
Mouse GPx3 CGUGUACCCCAGGUCAGGGGUGGUGUCUCUAUGAAGGAGGGGCCC------GAA---GCCC---UUGU------------GGGC------GGGCCUCCCCUGAGCCCGUCUGUGGUGCCAGCCCUU------SP
M.mulatta GPx3 CACGUACCCCAUGUCAGGGGUGGCGUCUUCAUGAGGGAGGGGCCC------AAA---GCCC---UUGU------------GGGC------GGACCUCCCCUGAGCCUGUCUGAGGGGCCAGCUCU-------SP
Orangutan GPx3 CACGUACCCCAUGUCAGGGGUGGCGUCUUCAUGAGGGAGGGGCCC------AAA---GCCC---UUGU------------GGGC------GGACCUCCCCUGAGCCUGUCUGAGGGGCCAGCCCU-------SP
Zebrafish GPx4 CUGGGUGUGAGUGAUGCCGCUCAUGGACUGAUGAAGGUUUGUUU------GGAAACCCCUU---GUU-------------GAGGAAA----GAACAGACCUGAUGUGUUUGGCGUGCACCUCCUC-------SP
Rat GPx4 UGACCCCUGGAGCCUUCCACCCCGGCACUCAUGACGGUCUGCCU-------GAAA--ACCAG--CCCG-----------CUGGUG------GGGCAGUCCCGAGGACCUGGCGUGCAUCCCCGCCG------SP
Mouse GPx4 UGACCCCUGGAGCCUUCCACCCCGGCACUCAUGAAGGUCUGCCU-------GAAA--ACCAG--CCUG-----------CUGGUG------GGGCAGUCCUGAGGACCUGGCGUGCAUCCCUGCCG------SP
C.reinhardtii GPx4 GGAGCACGUGUGUUCAGUGCCCGCCGCUGUAUGAUGCUGAGUCGCCGC----AAUUUGGCGCC-CUGAGU--------GGUGCCG---GCGGCGCUCAGCGGAUUCAGGAAUGAAUCAGGCGU---------SP
T.guttata GPx4 CCUGCUGCCCACGGAGCCUCCUCCAGCCCCAUGACGGGCUGCCUC------CAAU--CCAG---CUG-------------CUGGU-----GGGGCAGCCCCGACCCGAGGCGUGCAGCUGCUGGACAGAA--SP
Chicken GPx4 UGCUCCCCGUGGGCCCCCUCCUCCAGCACCAUGACGGCCUGCCUU------GAA---GCCAG--CUUG-----------CUGGU------GAGGCAGACCCGAAGAUUCGGCGUGCACCUGCUGGA------SP
B.microplus GPx4 -CGUGGACUGCUUCCUGGGCAAGAGACCUUAUGACGGGCAAUCUA------CAAA--CCGU---AAUUU-----------GCGGC-----UGGCUUGCCCUGAUGUUUCUCCAGUCUUGAGUCGAGAAAGA-SP
C.reinhardtii MsrA UUGUUAUUUCCUAGAUCCGCGCUGAAAAGUAUGAUGUGCGCGGCCCU-----CACG-GCGUCA-CCCCGC--------UGGCGCA----AGGGCCAGCACUGAAGGAACACGAGGCGGGGGCUG--------SP
D.virilis SPS2 UUUUUGUGAAGCGAAUUGACUAUUCAACUUAUGAUUACUAUUUC------AUAAA--GGCU---UCU-------------GGCUGG-----GAAAUAUUAUGAACGGUUUUAUGUGUAAAUAUAA-------SP
D.erecta SPS2 GUUAGGUGGUGCAAAUUAAUUAUUCAACCUAUGAGGAUUAUUUC------AUAAA--GGCC---UUCU------------GGCUCG-----GAAAUAGUCUGAAAUUUAUUGUACAUGCGAGG---------SP
Fly SPS2 GUUAAGUGGUGGUAAUUAAUCAUUCAACUUAUGAGGAUUAUUUCU------UAAA--GGCC---UCU-------------GGCUC-----GGAAAUAGUCUGAACCUUAUUGUACACGCGAUA---------SP
Rat SPS2 -GCCAUAGCCACCUUACUUGGUCUCUGAUAAUGAUGUUUCUCCC-----UCUAAC--UCCU---AAUA------------AGGACU-----GGGAGAGGCUGAUCAAACCUCAGAGCCAGGUGUUGGCGGC-SP
Trout SPS2 ---UCAGCUCAAAGCCCCCCCUACCUGUUUAUGAAGCUCCGCCU-----UCCAAA--CCUCA--GCCAA----------UGGGGCC-----AGGCGGAGUGGAUGUCUGUCUCAGGAAGGGGGUGGGGCUC-SP
D.simulans SPS2 GAUAAGUGGUGGUAAUUAAUUAUUCAACUUAUGAAGAUUAUUUCU------UAAA--GGCC---UCU-------------GGCUC-----GGAAAUGGUCUGAACUUUGUUGCACACGCGAGG---------SP
X.laevis SPS2 ACAAUUUGUAUUCACUUCCUCCUUCUGUCUAUGAUGCUGCUUCC----UGUUAAA--CCC----UACA-------------GGGCU-----GGAAGUGGUGGAAACCAAAUGAGAAGAGGGGAU--------SP
X.laevis SPS2 ACAAUUUGUAUUCACUUCCUCCUUCUGUCUAUGAUGCUGCUUCC----UCUUAAA--CCC----UACA-------------GGGCU-----GGAAGUGGUGGAAACCAAAUGAGAAGAGGGGAU--------SP
D.mojavensis SPS2 GUUUAACGAGUCAAACUGAGUGUUCAACUUAUGAUUAUUAUUUC------GUAAA--GGU----UUUG-------------GCUGG-----GAAAUAAUAUGAAUUGAUUUAUAUGUAAAUAUA--------SP
Mouse SPS2 AAGACUAGCCACCUGACUUGGUCUCUGAUAAUGAUGUCUCUCCC-----UCUAAC--UCC----CAGUAA-----------GGACU-----GGGAGAGGCUGAACAAACCUCAGAGCCAGGUGUCG------SP
D.ananensis SPS2 AGUAAAUUGUUUAAAAUAAUUAUUCAUUCUAUGAUGACAAUUUC------AUAAA--GGU----CUAAAA-----------ACCAG-----GAAAUAGUCUGAAAAUAAUUGUACACUUUAAUG--------SP
D.grimshawi SPS2 UUUUAAUGCAUCGAAUUGAGGAUUCAACUUAUGACUAUUAUUUCGC-----AAA---GGCU---UUU-------------AGCUG-----GGAAAUAUUAUGAAUUGUUUUAUAUACGUAUUAAUAAAAU--SP
Cow SPS2 ---UCCAGCCACCUUACUUGGUCUCUGUUAAUGACGUCUCUCUC-------UAAACCCCU----UUA--------------AGGACU----GGGAGAGGCAGACCAAACCCCAGAGACCAGGAUUU------SP
D.sechelia SPS2 GAUAAGUGGUGGUAAUUAAUUAUUCAACUUAUGAGGAUUAUUUCU------UAAA--GGCC---UCU-------------GGCUC-----GGAAAUAGUCUGAACUUUAUUGUACACGCGAGG---------SP
A.gambiae SPS2 GUACUUUUGGGGCGGGUGCAAUUCAAGCGUAUGAAACGAACUUC------GUAAA--GGCU---GCAAA-----------GGUCGG-----GAAGUUUGUGGAAGCUUUCUUGAACGAUCCGGCCA------SP
C.intestinalis SPS2 ---GAACUUAACCCACCACAUAGCAGCUUAAUGAAAUCCACUUUU------AAAA--UUUGU--AUGAAA---------ACAAAG-----GAAAGUGGGAUGAAGCCCUGCUUGUUAUGUUGGAGGUUA---SP
Zebrafish SPS2 AACAGAACAGCAGUGUCCAGUGUCCUCUUUAUGACACCUCUCUC-----UUUAAC--CCCA---GCUAA-----------UGGGAC-----GGGUGAGGUUGAUGUUAGAAAGGAAUGGAUAGGCUGA----SP
A.aegypti SPS2 --UGAAGGUAUCACUUGCAAAGGAGAACGUAUGAAGCGGACUUUU------AAA---GGC----UGAAAU-----------GCUG-----GUAAGUUUGUGGAAGUUUUUCUCUUUUGCAGAUGGUAGAUG-SP
D.persimilis SPS2 AGGUAAUACAAACAAUUGAUUAUUCAGCCUAUGACGGAUAUUUC------AUAA---AGGCU--UAA------------AGCUUG------GAAAUAUUUGGAACUUUACAUUUUUAAAUGUGUA-------SP
D.pseudoobscura SPS2 AGGUAAUACAAACAAUUGAUUAUUCAGCCUAUGACGGAUAUUUC------AUAA---AGGCU--UAA------------AGCUUG------GAAAUAUUUGGAACUUUACAUUUUUAAAUGUGUA-------SP
D.yakuba SPS2 GUUAAGUGAUACAAAUUAAUUAUUCAACUUAUGAGGACUAUUUCU------UAAA--GGC----CUUG-------------GCUC-----GGAAAUAGUCUGAACAUUAUUGUACAUGAGAGG---------SP
M.mulatta SPS2 ACCUGCAACCAUCUGACUUGGUCUCUGUUAAUGACGUCUCUCCC-----UCUAAAC-UCC----AUUAA------------GGACU-----GGGAGAGGCAGAGCAAGCCUCAGAGCCCAGGCCU-------SP
D.virilis SelH GCGUCGAUAGUUUUUCAGCAAUAGCGCCAUAUGAUCAUUAAACGGU-----AAAA--CCC----UAAC-------------GGGA----GCCGUUCACUGUGAAACUUUUGCCUGUAAGCUGAAGAAUU---SP
D.erecta SelH ----AACAAACCUUUCUACAAUAGAGCCCCAUGAUCGAUGAUUGG------CAAA--UCCU--CUCG-------------AGGAA-----CCAAUUAUUGAGAACCUUUUUGCCUUUGUUGAUUGUAUAAU-SP
Salmon SelH CAUCCGUGGUUUGUAGCAGCUGGAUGCAGAAUGAUGAGGACUGAC------CAACC-GGG----UUGCU------------CCCUA----GUCCUUCCUCUGAUGACCCAAGCGUCAAGCUCCUCUGG----SP
Fly SelH -CAAAACAAAGCGUUCAGCAAUAGAGCCCUAUGAUCGAUGAUUGG------CAAA--UCCU--CUCG-------------AGGAA-----CCGAUCGUUGAGAACCCCUUUGCCUUUGUUGAUCGCUCAAU-SP
D.sechelia SelH CCAAAACAAAGCGUUCAGCAAUAGAGCCCUAUGAUCGAUGAUUGG------CAAA--UCCU---UUCG------------AGGAA-----UCGAUCGUUGAGAACCACUUUGCCUUGGUUGAUCGCUCAA--SP
Trout SelH CAUCUGGGGUUUGUAGCAGCUGGACGCAGAAUGAUGAGGACUGAC------CAAACCGGGU---UGC-------------ACCCCA----GUCCUUCCUCUGAUGACCCCAGCGUCAAGCUCCUCUGG----SP
D.simulans SelH -CAAAACAAAGCGUUCAGCAAUAGUGCCCUAUGAUCGAUGAUUGG------CAAA--UCCU--CUCG-------------AGGAA-----CCGAUCGUUGAGAACCCCUUUGCCUUUGUUGAUCGCUCAAU-SP
A.gambiae SelH --CUUUAAUUUCUUCGAAUCGCCAUGCCGCAUGACGAAGCCUGAG------CAAA--CCC----CACGU------------GGGA-----CUCGAGCCUUUGAAGCUCUGCUGGCGUUUCGGUAGA------SP
D.mojavensis SelH ACAUCGAUAGUUUUUCAGCAGUAGCGCCAUAUGAUCAUUGAACGGU-----AAA---UCC----CCAACA-----------GGA-----GCUGUUCUUUGUGAAGUUUUUGCCUGUAAGCUGAAAAUCU---SP
A.aegypti SelH UUCGCGUUUGUCCGUUUACAUAUUUGUCGUAUGAAGAUGUUUAGGU-----AAA---CCU----GAAA-------------AGG-----ACCUAGACGUUCGAAGUCAACAAUGGUAGAUUGAAG-------SP
D.ananensis SelH --AUAGAAAUCUCCGCCAGCAAUAGGCCUUAUGAAGUGUGAUCGG-----CCAA---UCCU--CUCC-------------AGGAA-----CCGACCACACUGAACCACAAUUUUUGUUUGCCUUUGUCUG--SP
D.yakuba SelH ---AAACGAAUCUUUCAGCAAUAGAGCCUUAUGAUCGAUGAUUGG------CAAA--UCCU--UUCG-------------AGGAA-----CUUAUCAUUGAGAACCCUUUUGCCUUUGUUGAUUGCUUAGU-SP
D.grimshawi SelH CGUCAUCAAUUUUUUCAGCAAUAGCGCCAUAUGAUCAUUAAACGGU-----AAA---UCCC---UUAC------------GGGA-----ACUGUUCAGUGUGAAACUUCUGCCUCAAAGCUGGUUAAUU---SP
D.grimshawi SelH ----AUCAAUUUGCUCAGCAAUAGCGCCAUAUGAUCAUUAAACGGU-----AAA---UCCC---UUAC-------------GGGA----ACUGUUCAGUGUGAAACUUCUGCCUCAAAGCUGGUUA------SP
D.persimilis SelH ---GAUAAAUAUUUCUGGCAAUAGAGCCCCAUGAACGAUGAUCAG------CAAA--UCC----CGUGC------------GGAA-----CCGAUUAUUGUGAAGCCCAUUCGCAUUGCCUUUGC-------SP
D.pseudoobscura SelH ---GAUAAAUAUUUCUGGCAAUAGAGCCCCAUGAACGAUGAUCAG------CAAA--UCC----CGUGC------------GGAA-----CCGAUUAUUGUGAAGCCCAUUCGCAUUGCCUUUGC-------SP
X.laevis SelI -AUCAAUAGAAUAGCAGCGGCCGUGCUUGAAUGAAGGGCGUAUCU------AAAG--CC-----UGUGGUUU----------GGACA---GGGUACACUCGGAGGCAGCAAGCGCAGCCGCUGC--------SP
Mouse SelI ----UUCCACUGAAUGAAGUUUGUGCUUAAAUGAAGAGUGUG------UCUUAAAC-CCUUUU-UUUU----------GACAGGU--------UGCACUUGGAUAAAAUAGGCACCACUGUGUUGAU-----SP
Chicken SelI -------AUUUAAUGAAGAUCUGUGCUUGAAUGAAGAGUGUAGCUU-----AAAC--CCAG---GCU-------------CUGGAA---AGGCUGCAUCCGGAAGCAAACAAGCACAGCAGAUU--------SP
O.latipes SelJ -AAGAUUGCUGAGCUUUGGCAGAGCAUCGAAUGAAGGCUUUUGUCU------AA---AC-----UUAU--------------GUG----AGGCAGAAGCCUGAUGUUUUUUUAUGUCUGCAAAAGGAU----SP
D.virilis SelK GUAUUAGAUCUCGCAAGAUUUUUUGCGCAUAUGACGCAGCAUUC------AUAA---ACUCA--ACGC-----------UGAGUG------GAAUGUUGCUGAAUGGAUCUAUGCUGAUUUGGAGCU-----SP
D.erecta SelK -------CUGAUCCCGCCCAUGUGGCGCAUAUGACGCAGUUGUUU------UAAA--CUCG--UACU-------------CGAGC-----GGACAACUGCUGAAUACGAUUAUUCACUGAUUCCUGGGU---SP
Rat SelK ACAAGGACUGCUCUGUGUCCUCACAGAAGAAUGAGGUCAUGCUGGG------AAC--UCC----CUCUGCA----------GGA-----UCUGGCCUGACUGAUGUGCAGUUCUAUAAAUGUACAUGUG---SP
D.simulans SelK -------UUUAUCCCGCCCACGUGGCACUUAUGACGCAGUUGUCU------UAAA--CUCG--GACU-------------CGAGC-----GGGCAAUUGCUGAAUACGAUUGAUCACUGAUUCCUUGGCC--SP
Dog SelK ACAAGGAUUGCUCUGUGCCUUCACAGACGGAUGAGGUUGUGCUAGG------AAU--UCCCU--CCCC-----------AGGGA-----UCUGGCAUGACUGACAUGCAGUUCUAUAAAUGCACAUGUU---SP
D.mojavensis SelK UGUGUUAGAUCUCGCAAUUCAUUUGCGCUUAUGACGCAAUAUUC------AUAA---ACUCA--UCAUU----------UGAGUG------GAAUAUUGCUGAUACAUCUACGCGGAUAUGACUUA------SP
Mouse SelK ACAAGGAUUGCUCUGUGUCCCCACAGAUGAAUGAGGUCAUGCUGGG------AAU--UCC----CUCUGCA----------GGA-----UCUAGCCUGACUGAUACGCAGUUCUAUAAAUGUACAUGUU---SP
Mouse SelK ACAAGGAUUGCUCUGUGUCCUCACAGAUGAAUGAGGCCAUGCUAG------CAAU--UCC----CUCUGCA----------GGAU-----CUGGCCUGACUGAUACACAGUUCUAUAAAUGUACAUGUU---SP
Chimp SelK ACAAGGACUGCUCUGUGUCCUCACAGAUGAAUGAGGUCAUGCUGG------GAA---UUCCCU-CUGC----------AGGGAA------CUGGCCUGACUGACAUGCAGUUCCAUAAAUGCAGAUGUU---SP
D.ananensis SelK ----------AUUUCGUCCCUGUGGCGUUUAUGACGCAGUGUUCC------UAAA--CUC----UAACCU-----------GAGC-----GGAGUACUGCCGAACAAUGGAUCCUUGAUUUCUGGGU-----SP
D.melanogaster SelK -------UUUAUCCCGCCCAUGUGGCGCUUAUGACGCAGUUGUCU------UAAA--CUCG---AACU------------CGAGC-----GGGCAAUUGCUGAUUACGAUUAACCACUGAUUCCUGGGUC--SP
D.grimshawi SelK CAUAGGAUCUCGCAGCAUAUUUUUGCGCAUAUGACGCAAUAUUC------AUAA---ACUC---UUUAAUUC--------GAGUG------GGAUAUUGCCGAGACGGUCUGUGUGAAUUGGGG--------SP
Human SelK ACAAGGACUGCUCUGUGUCCUCACAGAUGAAUGAGGUCAUGCUGG------GAA---UUCCCU-CUGC----------AGGGAA------CUGGCCUGACUGACAUGCAGUUCCAUAAAUGCAGAUGUU---SP
Cow SelK ACAAGGAUUGCUCUGUGUCCUCACAGACGAAUGAGGUCAUGCUGGG------AAU--UCCCU--CCGC-----------AGGGA-----UCUGGCAUGACUGACAUGCAGUUCUAUAAAUGCACGUUUG---SP
Horse SelK --UAAGGAUUGCCCUGUGUCCUCACAGAUAAUGAGGUCGUGCUGGG------AAU--UCCCU--CCAC------------AGGGA----UCUGGCAUGACUGACAUGCAGUUCUAUAAAUGCGUAUGUUUG-SP
D.sechelia SelK -------UUUAUCCCGCCCACGUGGCACUUAUGACGCAGUUGUCU------UAAA--CUCG---GACU------------CGAGC-----GGGCAAUUGCUGAAUACGAUAGAUCACUGAUUCCUUGGCC--SP
M.fascicularis SelK ACAAGGACUGCUCUGUGUCCUCACAGAUGAAUGAGGUCAUGCUAG------GAA---UUCCCU-CUAC----------AGGGAA------CUGGCCUGACUGACAUGCAGUUCCAUAAAUGCAGAUGUU---SP
Pig SelK ACAAGGAUUGCUCUGUGUCCUCACAGAUGAAUGAGGUCUUGCUGGG------AAU--UCCCU--CCAC-----------GGGGA-----UCUGGCAUGACUGAUAAUGCAGUUCUAUAAAUGCACAUUUU--SP
A.gambiae SelK GACCCGGGGCCCGUAGGGACACUCCUACGUAUGACGGGCGCAUCC------UAAA--CCU----UCGCUACCAAAAC----AGGC-----GGAUGCGUCCCGAAGAGUGGGCCGCGGCGCAG----------SP
A.gambiae SelK GACCCGGGGCCCGUAGGGACACUCCUACGUAUGACGGGCGCAUCC------UAAA--CCU----UCGCUACCAAAAC----AGGC-----GGAUGCGUCCCGAAGAGUGGGCCGCGGCGCAG----------SP
D.yakuba SelK -------UUUAUCCCGCCCAUGUGGCGCAUAUGACGCAGUUGCC------UUAAA--CUCG---GAUU------------CGAGC-----GGACAACUGCUGAAUACGAUUAAUCACUGAUUCCUGGGUC--SP
M.mulatta SelK ACAAGGACUGCUCUGUGUCCUCACAGAUGAAUGAGGUCAUGCUAG------GAA---UUCCCU-CUAC----------AGGGAA------CUGGCCUGACUGACAUGCAGUUCCAUAAAUGCAGAUGUU---SP
C.reinhardtii SelM GCAUGGCCAUGCAUGGCGUAGCCGGUGGAUCUGAGAGGGGCCGCC-----CACAA--CUGC---GCCA------------GCAGC-----GGGGGCCUCUUGAGCAAAACCACCUGCUGAUGC---------SP
Trout SelM CUAAUGACUUCCUGUCCGCUGUGGAACUGAAUGACGCCCCUGGCU-----GUAA---AAUC---UCCU------------GAUU------GGCUUGGGGCCGAUGCAAUGUGUCCUGGUGGGUAGGGCUUAGSP
C.intestinalis SelN UACCUUUUUCAUGUGACAUCAUCAACUAGUAUGACGUAAUCAUCU------UAA---ACGU---CACA------------ACGU------GGAUGGUUGCCGAGGUUGAAGUUGAUGGAUGUAACG------SP
Human SelO CUGCCCUGGCCCAUGCACACCCGUCUUUCCAUGAUGGCAGAGAC------AUCCA--GUCAG--GAC------------CUGACCC-----GUCUCUGUCUGAGGCCGGCUCAGCAGUGCAGCC--------SP
Rat SelO -ACUGGGAUGCCUGUCCUCACGGUCUCUCCAUGACGGCAGAGGU------CUCCA--GUCA---AAACC-----------UGACCC-----AUCUCUGUCUGAUACUACCUUAGCAGUACUGCC--------SP
Mouse SelO ACCGCUGGGAUGCCUGUCCUCAGUCUCUCCAUGACGGCAGAGGU------CUCCA--GUCA---AAACC-----------UGACCC-----AUCUCUGUCUGAUACUACCUUAGCAGUACUAC---------SP
M.mulatta SelO CUGCCUGGGCCCAUGCACACCUGUCUUUCCAUGAUGGCAGAGAC------AUCCA--GUCAG--GAC------------CUGACCC-----GUCUCUGUCUGAGGCCAGCUCAGCAGUGCAGCC--------SP
Human SelP UUUUCUUUUUCCAGUGUUCUAUUUGCUUUAAUGAGAAUAGAAAC------GUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAAUUAGCAGUUUAGAAUGGAGGAA----SP
Salmon SelP UCCUCCUCCGUUUUGCUCCCUCCAUCCAAAAUGAAGGCAGGCAC------AGAA---ACUA---CCCUC-----------UAGUG------GUGUCUGUCUGAUGUCCGGCUGGGGAGAGGGGAG-------SP
Rat SelP UUUUCUUUCUCCAGUGUUCUAGUUACAUUGAUGAGAACAGAAAC------AUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGCUCGUAAUUAAGAACGGAGAAA----SP
Cow SelP UUUUCUUUUUCCAGUAUUCUACUUGCGUUAAUGAGAACAGAAAC------GUAAA--CUA----UAACC------------UAGGG-----GUUUCUGUUGGAUGGUUGGCAACUAAGAAUGGAGGAA----SP
M.fascicularis SelP UUUUCUUUUUCCAGUGUUCUAUUUGCUUUAAUGAGAAUAGAAAC------GUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGUUAGCAAUUUAGAAUGGAGGAA----SP
Trout SelP GGUGACAGGUCCUGCUCUCCUCUGCAGUUUAUGAAGUCUGCAGGUC-----AAA---CUC----UACG-------------GAGGU----GUCUGUAGAUAGAUGCUGUGCUAAGGAAAGUUGGAC------SP
X.tropicalis SelP UGUUCAUCACUUGAUUUGUUGCUUGCGUUAAUGAUGGCAGAAGC------AUAAA--CUA----CAAAA------------UAGGG-----GCUUCUGUCUGAGUCUGGCAAACAGAAACUGGUGA------SP
Dog SelP UUUUCUUUUUCCAGCAUUCUACUUGCAUUAAUGAAAACAGAGAC------AUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGUUAGCAAUUUAGAAUGGAGGAA----SP
Zebrafish SelP -UUCACCUCUAAAUGCUUUAUGUGGUCUUUAUGAAGGCAGGUGC------AGAA---ACUA---UGCAC-----------UAGUG------GUGUCUGUCUGAUGUUUGGCCAUACAGAGCAGA--------SP
Mouse SelP UUUCCUUUUUCCAGUGUUCUAGUUACAUUAAUGAGAACAGAAAC------AUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGCUUGUAAUUAAGAACGGAGAAA----SP
T.nigroviridis SelP GCCUUCUCCACUCUGCUCUCUCCAUCCGCAAUGAAAGCCGACGC------GGAAA--CUA----CGCUC------------UAGGG-----GCGUCUGCUGGAAGUCGGGCUGGGGAGAGGGGA--------SP
M.mulatta SelP UUUUCUUUUUCCAGUGUUCUAUUUGCUUUAAUGAGAAUAGAAAC------GUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGUUAGCAAUUUAGAAUGGAGGAA----SP
Orangutan SelP UUUUCUUUUUCCAGUGUUCUAUUUGCUUUAAUGAGAAUAGAAAC------GUAAA--CUA----UGACC------------UAGGG-----GUUUCUGUUGGAUAGUUAGCAAUUUAGAAUGGAGGAA----SP
Human SelR CCUGCCAGCCGCCCUGGCCCUGGUCACUGCAUGAUCCGCUCUGGU------CAAAC-CCU----UCC--------------AGGCCA---GCCAGAGUGGGGAUGGUCUGUGACCUGCUGGGAA--------SP
Salmon SelR CUGUCCUUCUGAAGGUGUGGAGGACAGUGGAUGAAGUGUCCUGUGA-----UAAAG-CCCA---CUC-------------UGGGACC---UCCAGGACACUGAUGGUCAAUGUCUUCACUGGAC--------SP
Cow SelR ---UGCCAGCUGCCCCAGCCCAGUCACUCUAUGAUUCUCUCUGGCU-----AAAC--CCU----UGC--------------AGGC----AGCCAGAGUGGUGAUGACCCGUGACCCGCUGGGGGAGCAGGCGSP
Trout SelR CUGUGCUGCUGAAGGUGUGCAGGACAGUGGAUGAAGUGUCCUGGG-----AUAAAG-CCCA---CUU-------------UGGGACC---UCCAGGACACUGAUGGUCAAUGUCUUCGCUGGAC--------SP
Pig SelR CGGCCCAGCCGGCUGCUCCAGGGUCACUGUAUGAUACACUCUGGCU-----AAAC--CCU----UGC--------------AGGC----GGCCAGAGGGGUGAUGGUCUGUGACUCCCGAGGGGA-------SP
C.lupus SelR GUUGCUGGCUGCUGCAGCUGCAGUCACUACAUGAUUCACUCUGGUU-----AAAC--CCU----UCC--------------AGGC----AGCCAGAGUGGUGAUGAUCUGUGACCUGCUAGAGG--------SP
X.tropicalis SelR GCUGUGCCUUUCCUAAUGGUCCAGCACCGAAUGAGUCACUGCAGAU-----AAA---CC-----CUCACU------------GGAC---GUCUGGGGUGAUGAAGAUGAUGUGCUGGGGGUUGGGCA-----SP
Dog SelR GUUGCUGGCUGCUGCAGCUGCAGUCACUACAUGAUUCACUCUGGUU-----AAAC--CCU----UCC--------------AGGC----AGCCAGAGUGGUGAUGAUCUGUGACCUGCUAGAGG--------SP
Zebrafish SelR ----AGAUGUGUCUACCAUGUGGAUGGCGAAUGAAACGUUCUGAA------GAAAAGCC-----CAGCGA------------GGAACA--UUCAGAGCGAGGAUGUGUAAAACAGCCUCAUGAGGCAC----SP
Zebrafish SelR ----AGAUGUGUCUACCAUGUGGAUGGCGAAUGAAACGUUCUGAA------GAAAAGCC-----CAGCGA------------GGAACA--UUCAGAGCGAGGAUGUGUAAAACAGCCUCAUGAGGCAC----SP
M.mulatta SelR CCUGCCAGCCGCCCUGGCCCUGGUCACUGCAUGAUCUGCUCUGGU------CAAAC-CCU----UCC--------------AGGCCA---GCCAGCGUGGGGAUGGUCUGUGACCUGCUGGGAA--------SP
Orangutan SelR CCUGCCAGCCGCCCUGGCCCUGGUCACUGCAUGAUCCGCUCUGGU------CAAAC-CCU----UCC--------------AGGCCA---GCCAGGGUGGGGAUGGUCUGUGACCUGCUGGGAA--------SP
X.laevis SelS GAAUUUUGUCACUGCAAUCUGGCACUUUACAUGAUGUCAUCCUUA------CAAA--UGGC---ACAGUA----------GCCAA-----UAGGGAUGACUGAUGUUGUUUGGUGGUAUGCACU--------SP
Human SelS UAGGACAGUCUCUGUGACAGGUUGCGUUGAAUGAUGUCUUCCUUAU-----CAA---UGGUG--AGCC-----------CACCA-----GUGAGGAUUACUGAUGUGGACAGUUGAUGGGGUUUGU------SP
Rat SelS CAGGGUGGUCUCUGUGACAGGAUGCGUUGAAUGAUGUCUUCCUUAU-----AAA---UGGUG--AGCC-----------CACCA-----GUGAGGAUUACUGAUGUACACAGUUGAUGGGGUU---------SP
Mouse SelS CAGGAUGGUCUCUGUGACGGGAUGCGUUGAAUGAUGUCUUCCUUAU-----AAA---UGGUG--AACC-----------CACCA-----GUGAGGAUUACUGAUGUUCACAGUUGACGGGGUU---------SP
Cow SelS UAGGACAGUCUCUGUGACAGCUUGCGUUGAAUGAUGUCUUCCUUGU-----AAA---UGGUG--AGCC-----------CACCA-----GCAAGGAUUACUGAUGCAGACAGUUGAUGGGGUUGUU------SP
Pig SelS CAGAAAAGUCUCUGUGACAGGUUGCGUUGAAUGAUGUCUUCCUUGU-----AAA---UGGUG--AGCC-----------CACCA-----GCGAGGAGCACUGAUGCAGACAGUUGAUAGGGUUGUU------SP
M.mulatta SelS UAGGACAGUCUCUGUGACAGGUUGCGUUGAAUGAUGUCUUCCUUAU-----CAA---UGGUG--AGCC-----------CACCA-----GUGAGGAUUACUGAUGUGGACAGUUGAUGGGGUUUGU------SP
O.anatinus SelT AUCUUUCUAAGGGCAACGUGAUUGAAACCUAUGAAGGCCUGUACUG------AAG--GCAG---CAAA------------CUGU-----UAGUACAGACCAGAUGUUCCUUUGCAGUCUCGUUGUAC-----SP
Human SelT GAUCAUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
Rat SelT GGAUUUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGUUUCUUGGCAGGCUCGUUGUACCUC--SP
Cow SelT GAUUUUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
Pig SelT GAUUUUUGCAAGAGCAGCGGGACUGACGUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
X.tropicalis SelT UUUGCAAUGGUGCCAACGGGGCUGGUAUUCAUGAAGGCUUGCACU------GAA---AACA---CUUGC-----------UGUU------AGUGUAGGCUGGAGGCUUCUCUGCCGUCUCGUUGCG------SP
Dog SelT AUUUUUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
X.laevis SelT UUUGCAAUGGUGCCAGCGGGACUGGUGUUCAUGAAAGCUUGCACU------GAA---AACA---CUUGC-----------UGUU------AGUGUAGGCUGGAGUUCUCCCUGCCGUCUCGCUGCA------SP
X.laevis SelT UUUUGCAAUGGUGCGGCGGGGCAGGUAUUCAUGAAGGCUUGCACU------CAA---AACA---UUUGC-----------UGUU------AGUGUAGGCUGGAGGCCUCUCUGCUGUCUCGCUG--------SP
Zebrafish SelT GCGCUCUCCUACGGUUGUGAGAUGGCAUUUAUGAAGGUUUGUGCU------GAA---AGUAG--CAA------------CUACU------AGCACACACCGGAUGUUCUGCGCUCUCCUCAUCG--------SP
Zebrafish SelT CCGGUCAGCGGGACUGUGGACUGUGGCAUAAUGAAGGCCUGCGCUG-----CAA---ACAG---CACA------------CUGU-----UGGCACAGGCUGGAUGCUCAGCCACCACACACACU--------SP
Mouse SelT GGAUUUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGUUUCUUGGCAGGCUCGUUGUACCUC--SP
S.japonicum SelT UCGUAUCAUAUUUGAGCUUCUUCGAGCCUUAUGAUAGUUCUCAUGU-----CAA---UCUCU--GUUC-----------AGAGA----ACAUGAGCAACUUGAUGCUAGCUCGUUCUAGUUCAA--------SP
Chimp SelT GAUCAUUUCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
T.guttata SelT GGUGGUUCCUGGGCCGCGUGGUGCAGACCCAUGAAGGCCUGCACU------GAA---GACAG--CCA------------CUGUU------GGUGCAGGCUGGAUGCCUCUCUUGCAGCCACGUUGUGCC---SP
M.mulatta SelT GAUCAUUGCAAGAGCAGCGUGACUGACAUUAUGAAGGCCUGUACU------GAA---GACAG--CAAG-----------CUGUU------AGUACAGACCAGAUGCUUUCUUGGCAGGCUCGU---------SP
T.nigroviridis SelU AUUAGGUGCUGGUGAUCCGCGUGUGUGACAAUGAUAACUUGACUC------UAAA--CUC----GACUUG-----------GAGAU-----GAGCAAGUUUGAUGCAGUACACAUAUGCGGACA--------SP
Trout SelU AGCGUGACUUGUGUGUGGUCUGUGUUAUUAAUGAAGACCUGACUGU-----AAA---CUCG---GCAA------------CGAGG-----GGAGCAGGUUCGAUAUCCAAACACACACUGCCUC--------SP
X.laevis SelV UUUGCUUCCUUUAUCUUAACCGAAUGCCGAAUGAUGGGAAAGGCU------GAA---AUGCUC-ACU-----------GGGUAU------GGCUCCUCCCUGAUGUCACUGCGUGGAAUGUUAGGA------SP
Zebrafish SelV ------GUGGGACUCCUGGGUAGUGCAACAAUGAUGGUGACGUCC------AAA---GUGU---UUCAC------------GCAC-----GGAUGUUGCUUGAUGCUCUCCGCUCUUCCCAGGA--------SP
Salmon SelV ----UGUCAUCUCCUUGACAUUGCAUAAUAAUGAUGGUGGUGCUC------CAAU--UGUC---AAA-------------GACAU-----GGGUGCUGCUUGAUGCAACCUGCUCUGCCAGGGAGGU-----SP
Rat SelV ---UGGCCGGCCUUUCUUGGCAGCCGCUUCAUGACAGGAAGGACUG-----AAAU--GUCU---CAA-------------AGACCUG--UGGUCUUUCUUCGAUGUUCCUGCGGCCACCAAGUC--------SP
Pig SelV ---GGCCCAGCUCCUCUCGGCAGACGCUUCAUGACAGGAAGGACUG-----AAA---UGUCU--UGU------------GGACGCC---UGGUCCUUCCCUGAUGUUCUCAUGGCUGCUGGGCG--------SP
M.mulatta SelV ---GACCCAGCCCCUCUCAGCAGACGCUUCAUGAUAGGAAGGACUG-----AAAA--GUCU---UGU-------------GGACGCC--UGGUCUUUCCCUGAUGUUCUCGUGGCUGCUGUUGG--------SP
Rat SelW ---UGGCCGGCCUUUCUUGGCAGCCGCUUCAUGACAGGAAGGACUG-----AAAU--GUCU---CAA-------------AGACCUG--UGGUCUUUCUUCGAUGUUCCUGCGGCCACCAAGUC--------SP
Sheep SelW ---GGCCCAGCCCCUCUCGGCAGACGCUUCAUGACAGGAAGGACUG-----AAA---UGUCU--CUU------------GGACGCC---UGGUCCUUCCUUGAUGUUCUCACGGCCGCCGGUUG--------SP
Trout SelW -------UGUCAUCUCCUUGACAUUGCAUAAUGAUGGUGGUGCUC------CAAU--UGUC---AAA-------------GACAU-----GGGUGCUGCUUGAUGAAACCUGCUCUGCCAGGGAGGU-----SP
N.vectensis SelW --CAGGCAAGAAAACUUCCAGUUAGUGUUUAUGACAGGGUUGACU------GAA---ACACA--AGCA------------UGUGU----GGCCAUUUCCUUGAUGAUAUGACAGCUCUACUGGAAA------SP
X.laevis SelW UUUGCUUCCUUUAUCUUAACCGAAUGCCGAAUGAUGGGAAAGGCU------GAA---AUGCUC-ACU-----------GGGUAU------GGCUCCUCCCUGAUGUCACUGCGUGGAAUGUUAGGA------SP
Mouse SelW ---UGGCCGGCCUUCCUUGGCAGCCGCUUCAUGACAGGAAGGACUG-----AAAU--GUC----UUA--------------GACCUG--UGGUCUUUCCUCGAUGUUCCUGCGGCCACCAAGUC--------SP
A.elegantissima SelW UGCAUAUUUUAAUCCAGAUGACAUGAUGUUAUGAUGGAAUGGGU------GUAAA--CACAAG-AAGU----------CUUGUGCA----GCCACAUUCUGGAUGCUUCUUCUGUGUCUUCUGGAAU-----SP
C.reinhardtii SelW UUUCCUGUUUGGCGGGUUGCUGGGUGAGACAUGAUGGGCGCGGGCU----UUAA---AGGGCU-ACA-----------GGCCCUU-----GGUCCGCCCCGGAUGCAAAUGAUCACCCUAGGCA--------SP
Orangutan SelW ---GACCCAGCCCCUCUCAGCAGACGCUUCAUGAUAGGAAGGACUG-----AAAAA-UCU----UGU--------------GGACACC-UGGUCUUUCCCUGAUGUUCUCGUGGCUGCUGUUGG--------SP
Human SelW ---GACCCAGCCCCUCUCAGCAGACGCUUCAUGAUAGGAAGGACUG-----AAAA--GUCU---UGU-------------GGACACC--UGGUCUUUCCCUGAUGUUCUCGUGGCUGCUGUUGG--------SP
Salmon SelW ----UGUCAUCUCCUUGACAUUGCAUAAUAAUGAUGGUGGUGCUC------CAAU--UGUC---AAA-------------GACAU-----GGGUGCUGCUUGAUGCAACCUGCUCUGCCAGGGAGGU-----SP
Cow SelW ---GGCCCAGCCCCUCUCGGCAGACGCUUCAUGACAGGAAGGACUG-----AAA---UGUCU--CUU------------GGACGCC---UGGUCCUUCCCUGAUGUUCUCGCGGCCGCCGGUUG--------SP
M.fascicularis SelW ---GACCCAGCCCCUCUCAGCAGACGCUUCAUGAUAGGAAGGACUG-----AAAA--GUCU---UGU-------------GGACGCC--UGGUCUUUCCCUGAUGUUCUCGUGGCUGCUGUUGG--------SP
Chicken SelW CACCGCCCAGCUCUGCCGGCACAGCGCUCCAUGACGGGGGCGGCC------AAAAG-GCC----CACG-------------GGCACAG--GGCUGCUUCCAGAACCCGCGCACGGCACCGGAGC--------SP
Pig SelW ---GGCCCAGCUCCUCUCGGCAGACGCUUCAUGACAGGAAGGACUG-----AAA---UGUCU--UGU------------GGACGCC---UGGUCCUUCCCUGAUGUUCUCAUGGCUGCUGGGCG--------SP
C.intestinalis SelW AGACUCCAUUUCAUAUCACAUGAGCACUAUAUGACGAGACUAGUU------UAA---ACUG---UUU-------------CAGU------GACUAAGCUUUGAUGAUUUGUACUUAUGUGUAUGAA------SP
Zebrafish SelW ------GUGGGACUCCUGGGUAGUGCAACAAUGAUGGUGACGUCC------AAA---GUGU---UUCAC------------GCAC-----GGAUGUUGCUUGAUGCUCUCCGCUCUUCCCAGGA--------SP
Zebrafish SelW ------GUGGGACUCCUGGGUAGUGCAACAAUGAUGGUGACGUCC------AAA---GUGU---UUCGG------------GCAC-----GGAUGUUGCUUGAUGCUCUCCGCUCUUCCCAGGA--------SP
M.mulatta SelW ---GACCCAGCCCCUCUCAGCAGACGCUUCAUGAUAGGAAGGACUG-----AAAA--GUCU---UGU-------------GGACGCC--UGGUCUUUCCCUGAUGUUCUCGUGGCUGCUGUUGG--------SP
C.reinhardtii SelW1 UUUCCUGUUUGGCGGGUUGCUGGGUGAGACAUGAUGGGCGCGGGCU----UUAA---AGGGCU-ACA-----------GGCCCUU-----GGUCCGCCCCGGAUGCAAAUGAUCACCCUAGGCA--------SP
Human TR1 -AUUUGGCAGGGCAUCGAAGGGAUGCAUCCAUGAAGUCACCAGUCU-----CAA---GCC----CAUGU------------GGU------AGGCGGUGAUGGAACAACUGUCAAAUCAGUUUUAGCA-----SP
Rat TR1 UGACAUUCGGCAGAGCAUCACGGUGCGUCCAUGAAGUCACUAGCCU-----CAA---GCC----CAAGU------------GGU------GGGCAGUGACAGAAAGCUGUCGAUCUGUUGGGUUCAA-----SP
Horse TR1 CACUCGGCAGUGCAUCGAAGGGAUGCGUCCAUGAAGUCACUGGCCU-----CAAA--GCC----CAUGU------------GGU------GGGCGGUGAUGGAACAGCUGUCGAAGCAGUUUU---------SP
Cow TR1 CUCUUGGCAGAGCAUCAGAGCGAUGCGUCCAUGAAGUCACCAGCCC-----CAA---GCC----CCUCGU-----------GGU------GGGUGGUGAUGGAACCGUCAAAGCAGUUUUCUCUUGGC----SP
Chicken TR1 -AGACAGUGCAGGCUUCAGGCUGUGAUUUCAUGAAAGCAUGUGU-------GAAAU-GC-----CCU---------------GCUAA----ACAUCAGCUGGACUGUCAAUAUGCCCAUUGCAUUG------SP
T.thermophila TR1 -AAAUAAUACCUUCAACUGGUAGGAAUAUAAUGAUUAGAGAACUCCU-----AA---CCUC---ACU--------------GAGG----AGGGUUUUCUAUGAGGCAAGAUUAUUGAUUUUGUUGUAG----SP
T.thermophila TR1 AAAACAAAGUUAAUUUAUCUAAUAUGGAAAAUGACGAAUUUAGUCU-----AAA---CUGU---AAA-------------ACAG-----GGAUUAAAUUCUGAAAAAUAUAUGACAAUUUAGA---------SP
Dog TR1 ACAUUCGGCAUGCAUCGGCGUGGUGCGUCCAUGAAGUCACUGGCCU-----CAA---GCC----AUGC-------------GGU------GGGCAGUGAUGGAGCAACUGUCGAGCAGUUUUA---------SP
Mouse TR1 CAUCUGGCAGAGCAUCACAGGCAUGCGUCCAUGAAGUCACUGGCCU-----CAA---GCC----CAAGU------------GGU------GGGCAGUGACAGAAGAGCUGCCGGGUCUGUUGAGCUCA----SP
C.briggsae TR1 CGUUUGGUGAUCGCCAGUAAGGGCAGCUUUGUGACGACUCUGGGC------UAAA--CUC----CAUCGU-----------GAGC-----GCCUUUGGUCUGAUGCGCUCUGAAAACGGUCAC---------SP
Orangutan TR1 CAUUUGGCAGGGCAUCGAAGGGAUGCAUCCAUGAAGUCACCAGUCU-----CAA---GCC----CAUGU------------GGU------AGGCGGUGAUGGACAACUGUCAAGAUGAGUUUUAGCAUGA--SP
C.elegans TR1 ------GUGGUCGCUAGUAGAGGCAGCUUUGUGACGACCUUUGGC-----UAAA---CUC----CAUCGU-----------GAGC-----GCCUCUGGUCUGAUGCGCCUCCAAAACGUCCAC---------SP
M.mulatta TR1 -------CAGGGCAUCAAAGGGAUGCAUCCAUGAAGUCACCAGUCU-----CAA---GCCC---AUG-------------GGGU------AGGCGGUGAUGGAACAACUGUCAAAUCAGUUUUAGCAUGAC-SP
X.laevis TR2 UUGAGAAUGACACAUAAGGGGUAUCAGCUAAUGAAGGCUUGUGUA------UAAA--CCCAC--CCU------------GUGGGC-----UGGGCAGGUCUGAGCAUCUCUGAUUCUCUGUUACGUGUAA--SP
Human TR2 CACCCCCCCCCAGGCUCCUGGUGCCAGAUGAUGACGACCUGGGUG------GAAA--CCUAC--CCU------------GUGGG------CACCCAUGUCCGAGCCCCCUGGCAUUUCUGCAAUGC------SP
Rat TR2 -CAGCCUUCACACACUGCCAGUGUCAGAUGAUGACGGCCUGUGCAG-----AAA---CC-----CCCACGU-----------GGG-----CUGCCAGGUUUGAACCCCUGGCAUUUCUGGAGUGCU------SP
Mouse TR2 GCCAGCCUCUGACACUCCCAGCGUCAGAUGAUGAUGGCCUGGGC------AGAAAC-CCC----AUGU-------------GGGCC-----GCCCAGGUUUGAACCCCUGGCAUUUCUAGAGCACU------SP
Cow TR2 GGCACCACGCACCCCGGACCCUGCCAGAUGAUGAGGACCUGUGCGG-----AAA---CC-----CCCCGC------------GGG----CUGCCCAUGUCUGAGCCCCUGGCAUCACCCGGCGC--------SP
M.fascicularis TR2 GCACUCCUUCUAGGCUCCUGCUGCCAGAUGAUGACGACCUGGGUG------GAAA--CCCAC--CCU------------GUGGG------CACCCAUGUCCGAGCCCCCUGGCAUUUCUGCAGUGC------SP
Pig TR2 ACCCCCGCACCUCCAGGCUCCAUGCCAGAAAUGAAGACCUGCGCAG-----AAA---CCC----UCCGC------------GGG-----CUGCCCACGUCUGAGGACCCUGGCAUUUCCAGAG---------SP
E.granulosus TR3 CUGCGAGGAGGCAUAGGACGAAACCGUACUAUGACUCGAGACCCGU-----CAA---CCG----AGCUUUG----------CGGA----GCGGAUCUUGACGAUGUAGGUCGUCUCGUGUGCUCC-------SP
N.vectensis TR3 ACCACCCCUGCAAAUCUAUGCAGUUUAUAUAUGAUGGUCAAGUUGGC----AAA---CCCU---UUAA-----------AGUGGA----GCAGCUUAACCGGAUGAAGGCGUGUACUUGGUUCCUCGCA---SP