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Alignment Text XML ASN.1 Hit Table(text) Hit Table(csv)	Search Strategies ASN.1	Bioseq ASN.1	PSSM Text	PssmWithParameters ASN.1	[?]
gi|126302086|gb|AAXJ01000419.1|:subseq(0,7131).pep

Query ID: lcl|2054
Description: gi|126302086|gb|AAXJ01000419.1|:subseq(0,7131).pep
Molecule type: amino acid
Query Length: 486
Database Name: nr
Description: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects See details
Program: BLASTP 2.2.20+ Citation
Other reports: Search Summary [Distance tree of results] [Related Structures]
Search Parameters
Program	blastp
Word size	3
Expect value	10
Hitlist size	100
Gapcosts	11,1
Matrix	BLOSUM62
Threshold	11
Composition-based stats	2
Filter string	F
Genetic Code	1
Window Size	40
Database
Posted date	Mar 22, 2009 5:57 PM
Number of letters	2,786,930,639
Number of sequences	8,097,822
Entrez query	none
Karlin-Altschul statistics
Params	Ungapped	Gapped
Lambda	0.318048	0.267
K	0.135867	0.041
H	0.412838	0.14
Results Statistics
Length adjustment	139
Effective length of query	347
Effective length of database	1661333381
Effective search space	576482683207
Effective search space used	576482683207
Alignments Select All Get selected sequences

>gb|AAH54599.1|  Thioredoxin reductase 1 [Danio rerio]
 gb|AAI65853.1|  Txnrd1 protein [Danio rerio]
Length=600

 GENE ID: 352924 txnrd1 | thioredoxin reductase 1 [Danio rerio]
(10 or fewer PubMed links)

 Score =  534 bits (1375),  Expect = 9e-150, Method: Compositional matrix adjust.
 Identities = 269/488 (55%), Positives = 337/488 (69%), Gaps = 14/488 (2%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
             VYD+DL VIGGGSGGLA +K AA LG +V + D+V P+PQGT WGLGGTCVNVGCIPKK
Sbjct  112  EVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKK  171

Query  66   LLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A       D+   GWE     +HNWE M   V  YI SLNWGY+  LR  NV  Y
Sbjct  172  LMHQTALLGTAMEDARKFGWEFAEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVN-Y  230

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             N++A F++ + +K T+KRGKE+  TA   ++ATG RP   G PG  E CITSDD+F   
Sbjct  231  VNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLP  290

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALEC GF+AG G D T+MVRSILLRGFDQDMA R G+YME HG KF
Sbjct  291  YCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKF  350

Query  244  VHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEF-GVFDTVLMAVGRTGCAGWLSL  299
            + + +PTK E+ E    G+++V AKS     ++++  F G ++TVL+AVGR  C G + L
Sbjct  351  LRKFVPTKIEQLEAGTPGRIKVTAKS-----TESEEVFEGEYNTVLIAVGRDACTGKIGL  405

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            D AGV  N   GK+PV+  E TN+ +IYAIGD++EG  ELTPVAIQ+GK+LA RL+ GA+
Sbjct  406  DKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGAT  465

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDADC  418
               DY NVPTTVFTP+EYGS G  EE A + YG ++L VYHS F PL + +   R +  C
Sbjct  466  MKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTV-PGRDNNKC  524

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    + +V+G H LGP+AGE+ QG   AMK G TK  LD+T+GIHPTCAE FTT
Sbjct  525  YAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTT  584

Query  479  LTQIKEDG  486
            +   K  G
Sbjct  585  MEVTKSSG  592


>gb|AAI54785.1|  Thioredoxin reductase 1 [Danio rerio]
Length=602

 GENE ID: 352924 txnrd1 | thioredoxin reductase 1 [Danio rerio]
(10 or fewer PubMed links)

 Score =  533 bits (1374),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 270/489 (55%), Positives = 335/489 (68%), Gaps = 16/489 (3%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
             VYD+DL VIGGGSGGLA +K AA LG +V + D+V P+PQGT WGLGGTCVNVGCIPKK
Sbjct  112  EVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKK  171

Query  66   LLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A       D+   GWE     +HNWE M   V  YI SLNWGY+  LR  NV  Y
Sbjct  172  LMHQTALLGTAMEDARKFGWEFAEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVN-Y  230

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             N++A F++ + +K T+KRGKE+  TA   ++ATG RP   G PG  E CITSDD+F   
Sbjct  231  VNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLP  290

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALEC GF+AG G D T+MVRSILLRGFDQDMA R G+YME HG KF
Sbjct  291  YCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKF  350

Query  244  VHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEF--GVFDTVLMAVGRTGCAGWLS  298
            + + +PTK E+ E    G+++V AKS+         EF  G ++TVL+AVGR  C G + 
Sbjct  351  LRKFVPTKIEQLEAGTPGRIKVTAKSTE------SEEFFEGEYNTVLIAVGRDACTGKIG  404

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            LD AGV  N   GK+PV+  E TN+ +IYAIGD++EG  ELTPVAIQ+GK+LA RL+ GA
Sbjct  405  LDKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGA  464

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYGS G  EE A + YG ++L VYHS F PL + +   R +  
Sbjct  465  TMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTV-PGRDNNK  523

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY K++C    + +V+G H LGP+AGE+ QG   AMK G TK  LD+T+GIHPTCAE FT
Sbjct  524  CYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFT  583

Query  478  TLTQIKEDG  486
            T+   K  G
Sbjct  584  TMEVTKSSG  592


>ref|NP_898895.2|  thioredoxin reductase 3 [Danio rerio]
Length=602

 GENE ID: 352924 txnrd1 | thioredoxin reductase 1 [Danio rerio]
(10 or fewer PubMed links)

 Score =  533 bits (1374),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 269/488 (55%), Positives = 337/488 (69%), Gaps = 14/488 (2%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
             VYD+DL VIGGGSGGLA +K AA LG +V + D+V P+PQGT WGLGGTCVNVGCIPKK
Sbjct  112  EVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKK  171

Query  66   LLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A       D+   GWE     +HNWE M   V  YI SLNWGY+  LR  NV  Y
Sbjct  172  LMHQTALLGTAMEDARKFGWEFAEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVN-Y  230

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             N++A F++ + +K T+KRGKE+  TA   ++ATG RP   G PG  E CITSDD+F   
Sbjct  231  VNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLP  290

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALEC GF+AG G D T+MVRSILLRGFDQDMA R G+YME HG KF
Sbjct  291  YCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKF  350

Query  244  VHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEF-GVFDTVLMAVGRTGCAGWLSL  299
            + + +PTK E+ E    G+++V AKS     ++++  F G ++TVL+AVGR  C G + L
Sbjct  351  LRKFVPTKIEQLEAGTPGRIKVTAKS-----TESEEVFEGEYNTVLIAVGRDACTGKIGL  405

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            D AGV  N   GK+PV+  E TN+ +IYAIGD++EG  ELTPVAIQ+GK+LA RL+ GA+
Sbjct  406  DKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGAT  465

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDADC  418
               DY NVPTTVFTP+EYGS G  EE A + YG ++L VYHS F PL + +   R +  C
Sbjct  466  MKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTV-PGRDNNKC  524

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    + +V+G H LGP+AGE+ QG   AMK G TK  LD+T+GIHPTCAE FTT
Sbjct  525  YAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTT  584

Query  479  LTQIKEDG  486
            +   K  G
Sbjct  585  MEVTKSSG  592


>ref|XP_001492801.1|  PREDICTED: similar to thioredoxin reductase 3 [Equus caballus]
Length=565

 GENE ID: 100060514 LOC100060514 | similar to TXNRD3 protein [Equus caballus]

 Score =  527 bits (1358),  Expect = 9e-148, Method: Compositional matrix adjust.
 Identities = 266/488 (54%), Positives = 333/488 (68%), Gaps = 12/488 (2%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S YD+DL VIGGGSGGLA A+ AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPK
Sbjct  76   DSAYDYDLIVIGGGSGGLACAQEAAVLGKKVMVLDFVLPSPQGTSWGLGGTCVNVGCIPK  135

Query  65   KLLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A   +   DS   GWE      HNWE M + +  +I SLNWGY+  LR   V  
Sbjct  136  KLMHQAALLGQALIDSRKFGWEYNQQVKHNWETMTEAIQNHIGSLNWGYRLSLREKAV-A  194

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NS+  F++ + +K T+++G+E+  TA   +IATG RP   G  G  E CITSDD+F  
Sbjct  195  YVNSYGEFVEHHKIKATNRKGQETCYTAAKFVIATGERPRYLGIQGDKEYCITSDDLFSL  254

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQ+MA+++G YME HG K
Sbjct  255  PYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVK  314

Query  243  FVHEMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSL  299
            F+ + +P    + EK   GK+RV A+S+    +      GV++TVL+A+GR  C   + L
Sbjct  315  FLRKFVPVMIQQLEKGSPGKLRVVAESTEGPGAVE----GVYNTVLLAIGRDSCTRKIGL  370

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            +  GV  N   GKIPV+  E TN+  +YAIGD++EG LELTPVAIQ+GK+LA RLFGG  
Sbjct  371  EKIGVKINEKSGKIPVNDVEQTNVPYVYAIGDILEGKLELTPVAIQAGKLLARRLFGGRL  430

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADC  418
               DY NVPTTVFTP+EYG  G SEE A E +  ++L VYH+ F PL W +   R +  C
Sbjct  431  EKCDYINVPTTVFTPLEYGCCGLSEEKAIEVHKKENLEVYHTLFWPLEWTV-AGRDNNTC  489

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    +++VVG HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTT
Sbjct  490  YAKIICNKFDNERVVGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTT  549

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  550  LEITKASG  557


>ref|XP_002154390.1|  PREDICTED: similar to MGC81848 protein [Hydra magnipapillata]
Length=591

 GENE ID: 100212234 LOC100212234 | similar to MGC81848 protein
[Hydra magnipapillata]

 Score =  525 bits (1351),  Expect = 5e-147, Method: Compositional matrix adjust.
 Identities = 270/485 (55%), Positives = 337/485 (69%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DLFVIGGGSGGLA +K AA LGA+VA+ADFV PSP G+TWGLGGTCVNVGCIPKKL+
Sbjct  105  YDFDLFVIGGGSGGLACSKEAADLGAKVAVADFVVPSPAGSTWGLGGTCVNVGCIPKKLM  164

Query  68   HMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   E   DS   GW  E   SH+W  M+  +  +I SLNWGYK  LR  NVK Y+N
Sbjct  165  HQAALLGEAIHDSRHYGWNIEENISHDWAKMVDAIQQHIRSLNWGYKVNLRQKNVK-YYN  223

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
             +ATF+D +TL+LTDK GK   VTA   ++ATGGRP     PGA EC ITSDDIF     
Sbjct  224  MYATFLDNHTLQLTDKSGKVETVTADKFVLATGGRPTYPDIPGAKECAITSDDIFSLPYV  283

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGK L  GASYIALECAGF  G G DTTVM+RSI LRGFDQ MA ++  YME  G KF+ 
Sbjct  284  PGKVLFCGASYIALECAGFTHGIGMDTTVMMRSIPLRGFDQFMANKVVDYMETIGIKFLK  343

Query  246  EMIPTKFEKTEDG---KVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            +  P K EK E+G   K++V   + +    ++D    +F+TV++A+GR+ C   L L+N 
Sbjct  344  KYTPIKMEKVEEGTPGKIKVTYMNHNTNEEESD----IFNTVVVAIGRSPCTKGLGLENL  399

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  NP  G +  D+++ TNI+NIY IGD+++G  ELTPVAIQ+GK+LA RLF G+    
Sbjct  400  GVKLNPLNGFLISDEYDRTNIENIYGIGDILDGKPELTPVAIQAGKLLAKRLFNGSKVTC  459

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NV TTVFTP+EYG+ G SEE A E+YG+D I VYHS F P L A    R D  CY K
Sbjct  460  DYTNVATTVFTPLEYGACGLSEETAIEKYGEDNIEVYHSNFTP-LEATVPHRLDNVCYAK  518

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            V+C  K +++++G+H+LGP+AGE+IQG ++A K G  K +LDD +GIHPT AE FTTL +
Sbjct  519  VICNKKDEERILGMHVLGPNAGEIIQGFSIAFKVGAKKQHLDDLIGIHPTNAEIFTTLEK  578

Query  482  IKEDG  486
             K  G
Sbjct  579  TKRSG  583


>ref|NP_001116250.1|  thioredoxin reductase 3 [Canis lupus familiaris]
Length=586

 GENE ID: 484619 TXNRD3 | thioredoxin reductase 3 [Canis lupus familiaris]

 Score =  521 bits (1341),  Expect = 7e-146, Method: Compositional matrix adjust.
 Identities = 258/490 (52%), Positives = 333/490 (67%), Gaps = 16/490 (3%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S YD+DL VIGGGSGGLA A+ AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPK
Sbjct  95   DSAYDYDLIVIGGGSGGLACAQEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPK  154

Query  65   KLLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A   +   D+   GWE +    H WE M + +  +I SLNWGY+  LR   V  
Sbjct  155  KLMHQAALLGQALRDARKFGWEYSQQVKHTWETMTEAIQNHIGSLNWGYRLSLREKAV-A  213

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NS+  F++ + +K T+++G+E+  TA   ++ATG RP   G  G  E CITSDD+F  
Sbjct  214  YVNSYGEFVEHHKIKATNRKGQETCYTAAKFVLATGQRPRYLGIQGDKEYCITSDDLFSL  273

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PGKTLVVGASY+ALECAGF+AG G D T+MVRSILLRGFDQ+MA+++G YME HG K
Sbjct  274  PYCPGKTLVVGASYVALECAGFLAGIGLDVTIMVRSILLRGFDQEMAEKVGSYMEQHGVK  333

Query  243  FVHEMIPT---KFEKTEDGKVRVYAKSSS--DTMSDADSEFGVFDTVLMAVGRTGCAGWL  297
            F+ + +P    + EK   GK++V AKS+   +T+ +      +++TVL+A+GR  C   +
Sbjct  334  FLRKFVPVLVQQLEKGSPGKLKVVAKSTEGPETIEE------IYNTVLLAIGRDSCTRKI  387

Query  298  SLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGG  357
             L+  GV  N   GKIPV+  E TN+  +YA+GD++EG LELTPVAIQ+GK+LA RLF G
Sbjct  388  GLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEGKLELTPVAIQAGKLLARRLFAG  447

Query  358  ASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDA  416
                 DY NVPTTVFTP+EYG  G SEE A E Y  ++L VYH+ F PL W +   R + 
Sbjct  448  RLEKCDYVNVPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTV-AGRDNN  506

Query  417  DCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETF  476
             CY K++C    + +V+G H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E F
Sbjct  507  TCYAKIICNKLDNYRVIGFHVLGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVF  566

Query  477  TTLTQIKEDG  486
            TTL   K  G
Sbjct  567  TTLEITKSSG  576


>ref|NP_001116249.1|  thioredoxin reductase 3 [Gallus gallus]
Length=606

 GENE ID: 416031 TXNRD3 | thioredoxin reductase 3 [Gallus gallus]
(10 or fewer PubMed links)

 Score =  520 bits (1340),  Expect = 9e-146, Method: Compositional matrix adjust.
 Identities = 262/487 (53%), Positives = 336/487 (68%), Gaps = 16/487 (3%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL VIGGGSGGLA +K AA LG +V + D+V P+P GT+WGLGGTCVNVGCIPKKL+
Sbjct  118  YDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPLGTSWGLGGTCVNVGCIPKKLM  177

Query  68   HMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GW+      HNWE M++ V  YI SLNWGY+  LR  +V  Y N
Sbjct  178  HQAALLGQALKDSRAYGWQYDEQVKHNWEIMVEAVQNYIGSLNWGYRLSLREKSV-TYQN  236

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+++G+ +  TA   ++ATG RP   G PG  E CITSDD+F     
Sbjct  237  SYGEFVEPHKIKATNRKGQVTYHTAETFVLATGERPRYLGIPGDKEYCITSDDLFSLPYC  296

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQ+MA++IG +ME HG  F+ 
Sbjct  297  PGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQEMAEKIGAHMETHGVTFIR  356

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEF--GVFDTVLMAVGRTGCAGWLSLD  300
            + +PT+ E+ ED   G+++V AKS+         EF  G ++TVL+A+GR  C   + L 
Sbjct  357  KFVPTQVERLEDGTPGRLKVTAKSTE------GPEFFEGEYNTVLIAIGRDACTRNIGLQ  410

Query  301  NAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASR  360
              GV  N   GK+PV+  E TN+  +YAIGD+++G LELTPVAIQ+GK+LA RL+GG+S 
Sbjct  411  TIGVKINEKNGKVPVNDEERTNVPYVYAIGDILDGKLELTPVAIQAGKLLARRLYGGSST  470

Query  361  LMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDADCY  419
              DY NVPTTVFTP+EYGS G +EE A EEYG  +L VYHS F PL W +   R +  CY
Sbjct  471  KCDYINVPTTVFTPLEYGSCGLAEEKAIEEYGKQNLEVYHSLFWPLEWTV-PGRDNNTCY  529

Query  420  MKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTL  479
             K++C      +VVG H+LGP+AGE+ QG A A+K G TK  LD+T+GIHPTCAE FTT+
Sbjct  530  AKIICNKLDGNRVVGFHVLGPNAGEVTQGFAAAIKCGLTKELLDETIGIHPTCAEVFTTM  589

Query  480  TQIKEDG  486
               K  G
Sbjct  590  DITKSSG  596


>ref|NP_001087660.1|  MGC81848 protein [Xenopus laevis]
 gb|AAH81053.1|  MGC81848 protein [Xenopus laevis]
Length=596

 GENE ID: 447484 MGC81848 | MGC81848 protein [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  519 bits (1337),  Expect = 2e-145, Method: Compositional matrix adjust.
 Identities = 257/491 (52%), Positives = 331/491 (67%), Gaps = 12/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            D     YD+DL VIGGGSGGLA +K AA+ G +V + DFV P+PQGT+WGLGGTCVNVGC
Sbjct  104  DDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDFVVPTPQGTSWGLGGTCVNVGC  163

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   ++  DS   GWE      HNWE M + +  YI SLNWGY+  LR   
Sbjct  164  IPKKLMHQAAILGQSLKDSRKFGWEYEEQVKHNWETMREAIQNYIGSLNWGYRVALRDKQ  223

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V+ Y N++  F++ + +K T+K+GKES  TA   ++ATG RP     PG  E CITSDD+
Sbjct  224  VR-YENAYGEFVESHKIKATNKKGKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDL  282

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSI LRGFDQ+MA R G YME H
Sbjct  283  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDATVMVRSIFLRGFDQEMANRAGAYMETH  342

Query  240  GTKFVHEMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +P K E  E+   G+++V AKS+       D     ++TVL+AVGR  C   
Sbjct  343  GVKFIKQFVPIKVELLEEGTPGRIKVTAKSTQGDQIIEDE----YNTVLIAVGRDACTRN  398

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E T++ ++YAIGD+++G LELTPVAIQ+G++LA RL+ 
Sbjct  399  IGLEKIGVKINERNGKIPVSDEEQTSVPHVYAIGDILDGKLELTPVAIQAGRLLARRLYR  458

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDD-LIVYHSFFKPLLWALNKDRGD  415
            G+    DY NVPTTVFTP+EYG  G +EE A E YG++ L VYH+ F PL W +   R +
Sbjct  459  GSKVKCDYINVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTV-PSRDN  517

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              C+ K++C  + + +V+G H+LGP+AGE+ QG   AMK G TK  LD+T+GIHPTCAE 
Sbjct  518  NTCFAKIICNKQDNDRVIGFHVLGPNAGEITQGFGAAMKCGLTKEKLDETIGIHPTCAEI  577

Query  476  FTTLTQIKEDG  486
            FTT+   K  G
Sbjct  578  FTTMDTSKSSG  588


>dbj|BAH20464.1|  thioredoxin reductase [Emiliania huxleyi]
Length=495

 Score =  517 bits (1331),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 270/488 (55%), Positives = 337/488 (69%), Gaps = 19/488 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA +K AA+ G +VA+ DFVKPSP GTTWGLGGTCVNVGCIPKKL+H
Sbjct  7    QYDLLVIGGGSGGLACSKRAASHGKKVAVCDFVKPSPPGTTWGLGGTCVNVGCIPKKLMH  66

Query  69   MSAHTAETAGDSAGLGWELTA-SHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNSF  127
             +A   E   D+   GWE+ A  HNWE M+ NV  +I SLN+GY+S+L S  VK Y+N++
Sbjct  67   QAALLGEGMTDAESFGWEVAAPKHNWETMVGNVQGHIKSLNFGYRSDLMSNGVK-YYNAY  125

Query  128  ATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAPPG  187
            ATF+D +T++  DK+GK + +TA  I+I TGGRP     PGA E  ITSDD+F  K+PPG
Sbjct  126  ATFLDPHTVEAVDKKGKVTKITASEIVICTGGRPRYPDIPGAKELGITSDDVFALKSPPG  185

Query  188  KTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVHEM  247
            +TLVVGASY+ALECAGFI G GYDTTVM+RSI LRGFDQ MA     YM+ HG  F+   
Sbjct  186  RTLVVGASYVALECAGFIKGVGYDTTVMMRSIPLRGFDQQMAGLCKTYMQEHGVAFIEGA  245

Query  248  IPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGVHYN  307
            +PT  E T  G     AK  S  ++D     G +DTVL A+GR  C   + +D AGV  +
Sbjct  246  VPTAVEATPSG-----AKKVSWKLADGSVGSGEYDTVLFAIGRDVCTSAIGIDKAGVKLS  300

Query  308  PDKGKIPVDKFEMTNIDNIYAIGDVVEG--------MLELTPVAIQSGKMLAARLFGGAS  359
             + GK+P    E TN+ +IYAIGD+++G          ELTPVAIQ+GK+LA RL+ G S
Sbjct  301  SN-GKVPTVN-EQTNVPHIYAIGDIIDGEALNPPSATTELTPVAIQAGKLLADRLYAGKS  358

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADC  418
             LMDY  V TTV+TP+EYG+VG  EE A + +G+D I VYHS+FKPL W L   RGD  C
Sbjct  359  ALMDYSMVATTVYTPLEYGAVGLPEEEAIKLHGEDNIEVYHSYFKPLEWTL-PHRGDNVC  417

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C     ++V+G+H+ GP+AGEM QG AVA+KAG TKA+ DDTVGIHPT AE FT 
Sbjct  418  YAKLICLKPEGERVIGLHVCGPNAGEMTQGFAVAIKAGATKAHFDDTVGIHPTVAEEFTL  477

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  478  LAATKRSG  485


>ref|XP_001377333.1|  PREDICTED: similar to TXNRD3 protein [Monodelphis domestica]
Length=721

 GENE ID: 100026851 LOC100026851 | similar to TXNRD3 protein
[Monodelphis domestica]

 Score =  514 bits (1323),  Expect = 9e-144, Method: Compositional matrix adjust.
 Identities = 249/482 (51%), Positives = 331/482 (68%), Gaps = 16/482 (3%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
            + Y++DL VIGGGSGGLA +K AA  G +V + D+V P+P G +WGLGGTCVNVGCIPKK
Sbjct  233  ATYEYDLIVIGGGSGGLACSKEAANWGKKVMVLDYVTPTPLGKSWGLGGTCVNVGCIPKK  292

Query  66   LLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A   +   DS   GWE      HNWE M + +  YI SLNWGY+  LR  +V  Y
Sbjct  293  LMHQAALLGQALKDSRKFGWEYEENVKHNWETMTEAIQNYIGSLNWGYRVSLREKSVS-Y  351

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             NS+  F++ +T+K  +++G+E+  TA   +IATG RP   G PG  E CITSDD+F   
Sbjct  352  INSYGEFVEHHTIKAINRKGQETFYTAERFVIATGERPRYLGIPGDKEYCITSDDLFSLP  411

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTL++GASY+ALEC GF+AG G D T+MVRSILLRGFDQ++A++IG YME+HG  F
Sbjct  412  YCPGKTLIIGASYVALECGGFLAGIGLDVTIMVRSILLRGFDQEIAEKIGSYMEMHGVTF  471

Query  244  VHEMIPTKFEKTED---GKVRVYAKSS--SDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            + + IP   ++ E+   G+++V AKS+  S+T+       G ++TVL+A+GR  C   + 
Sbjct  472  LRQYIPVTIQQLEEGTPGRLKVVAKSTEGSETIE------GEYNTVLIAIGRESCTRKIG  525

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N + GKIPV+  E TN+  +YA+GDV+E  LELTPVAIQ+GK+LA RL+GG 
Sbjct  526  LEKIGVKINENTGKIPVNDEEQTNVSYVYAVGDVLEDKLELTPVAIQAGKLLARRLYGGQ  585

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
                DY NVPTTVFTP+EYG  G SEE A+E +  D I V+H++F PL W +     D  
Sbjct  586  LEKCDYINVPTTVFTPLEYGCCGFSEEKARELFNKDNIEVFHTYFWPLEWTIAGRENDT-  644

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            C+ K++C  + + +V+G H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FT
Sbjct  645  CFGKIICNKRDNNRVIGFHVLGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFT  704

Query  478  TL  479
            TL
Sbjct  705  TL  706


>gb|AAI67349.1|  MGC147163 protein [Xenopus tropicalis]
Length=596

 GENE ID: 779989 MGC147163 | hypothetical protein MGC147163
[Xenopus (Silurana) tropicalis] (10 or fewer PubMed links)

 Score =  513 bits (1322),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 254/485 (52%), Positives = 329/485 (67%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL VIGGGSGGLA +K AA+ G +V + D+V P+P+GT+WGLGGTCVNVGCIPKKL+
Sbjct  110  YDYDLIVIGGGSGGLACSKEAASFGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLM  169

Query  68   HMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   ++  DS   GWE      HNW+ M + +  YI SLNWGY+  LR   V+ Y N
Sbjct  170  HQAAILGQSLKDSRNFGWEYEEQVKHNWDTMREAIQNYIGSLNWGYRVSLRDKQVR-YEN  228

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++  F++ + +K T+KRGKES  TA   ++ATG RP     PG  E CITSDD+F     
Sbjct  229  AYGEFVEPHKIKATNKRGKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDLFSLPYC  288

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQ+MA R G YME HG KF+ 
Sbjct  289  PGKTLVVGASYVALECAGFLAGLGLDATVMVRSILLRGFDQEMANRAGAYMETHGVKFIK  348

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + +P   E  E+   G+++V AK++       D     ++TVL+AVGR  C   + L+  
Sbjct  349  QFVPISVELLEEGTPGRLKVTAKATEGDQIIEDE----YNTVLIAVGRDACTRNIGLEKI  404

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV   E T++  +YAIGD+++G LELTPVAIQ+G++LA RL+ G+    
Sbjct  405  GVKVNERNGKIPVSDEEQTSVPYVYAIGDILDGKLELTPVAIQAGRLLARRLYKGSKLKC  464

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDD-LIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G +EE A E YG++ L VYH+ F PL W +   R +  C+ K
Sbjct  465  DYVNVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTV-PSRDNNTCFAK  523

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  + D +VVG H+LGP+AGE+ QG   A+K G TK  LD+T+GIHPTCAE FTT+  
Sbjct  524  IICNKQDDDRVVGFHVLGPNAGEITQGFGAAIKCGLTKEKLDETIGIHPTCAEVFTTMDV  583

Query  482  IKEDG  486
             K  G
Sbjct  584  SKSSG  588


>ref|NP_001087786.1|  MGC85342 protein [Xenopus laevis]
 gb|AAH81224.1|  MGC85342 protein [Xenopus laevis]
Length=531

 GENE ID: 447610 MGC85342 | MGC85342 protein [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  513 bits (1322),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 265/491 (53%), Positives = 336/491 (68%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            +P +  YD+DL VIGGGSGGLAA+K AA  G +V + DFV PSP GT WGLGGTCVNVGC
Sbjct  40   NPDQITYDYDLIVIGGGSGGLAASKEAAKYGKKVLVLDFVTPSPLGTKWGLGGTCVNVGC  99

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++     HNWE M  +V  YI SLN+ Y+  L   N
Sbjct  100  IPKKLMHQAALLRQALKDSQKYGWQIADNIQHNWETMTDSVQNYIGSLNFNYRVALMENN  159

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            VK Y N +  F+  NT+K T+ RGK    TA   LIATG RP   G PG  E CITSDD+
Sbjct  160  VK-YENGYGEFVGPNTIKSTNSRGKSKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDL  218

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQ MA +IG+YME H
Sbjct  219  FSLTYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANKIGEYMEEH  278

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G+++V +++   T +  +     ++TVL+A+GR  C   
Sbjct  279  GVKFIRQFVPTKIEQIEAGMPGRLKVTSQAPDGTETTDE-----YNTVLLAIGRDACTRN  333

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV+  E TN+  IYAIGDV++  LELTPVAIQ+G++LA RL+G
Sbjct  334  IGLEIPGVKINEKTGKIPVNDEEQTNVPYIYAIGDVIQDKLELTPVAIQAGRLLAKRLYG  393

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
             ++   DY NVPTTVFTP+EYG+ G SEENA  +YG++ + VYHS+F PL W +   R +
Sbjct  394  DSTLKSDYVNVPTTVFTPLEYGACGLSEENAIRQYGEENVEVYHSYFWPLEWTV-PARDN  452

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K +++VVG H+L P+AGE+ QG AVA+K G TK  LD+T+GIHP CAE 
Sbjct  453  NKCYAKIICNLKDNERVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEI  512

Query  476  FTTLTQIKEDG  486
            FTTLT  K  G
Sbjct  513  FTTLTVTKRSG  523


>ref|XP_001014761.2|  thioredoxin and glutathione reductase family protein [Tetrahymena 
thermophila SB210]
 gb|EAR94708.2|  thioredoxin and glutathione reductase family protein [Tetrahymena 
thermophila SB210]
Length=489

 GENE ID: 4505589 TTHERM_00047660 | thioredoxin and glutathione reductase family
protein [Tetrahymena thermophila SB210] (10 or fewer PubMed links)

 Score =  513 bits (1321),  Expect = 1e-143, Method: Compositional matrix adjust.
 Identities = 263/483 (54%), Positives = 343/483 (71%), Gaps = 9/483 (1%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            + +D FVIGGGSGGLAAAK AA+ GARVA+ADFVKPSP GT WGLGGTCVNVGCIPKKL+
Sbjct  5    FKYDFFVIGGGSGGLAAAKEAASFGARVAVADFVKPSPVGTKWGLGGTCVNVGCIPKKLM  64

Query  68   HMSAHTAETAGDSAGLGW---ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYF  124
            H +A   E+      +GW   +    H W+ M++ V  +I  LNWGYK EL    VK Y+
Sbjct  65   HFAASYGESHEAQKNMGWTEIKEKNKHEWQPMVERVQAHIKKLNWGYKVELAEKEVK-YY  123

Query  125  NSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKA  184
            NS A+ + +NT++LT+++G++  VTA+YILIA GGRP     P   +  ITSDDIF  + 
Sbjct  124  NSLASIVGKNTIELTNRKGEKEQVTAKYILIAVGGRPTFLDIPNTEKLVITSDDIFSMQN  183

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
            PPGKTLVVGASYIALECAGF+AGFGYD TVMVRSILLRGFDQ++A++IG+YM  HGTKF+
Sbjct  184  PPGKTLVVGASYIALECAGFLAGFGYDVTVMVRSILLRGFDQEIAEKIGEYMARHGTKFI  243

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
               +P   E T DG+ RV  KS  +   D +    +FDTV++A+GRT     + ++  G+
Sbjct  244  RGTVPHHIEATPDGRRRVVWKSPVEGQGDVEE---IFDTVMLAIGRTSDTKNIGVETMGI  300

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
               P+ GKI  +  + TN++NI+AIGD V+   ELTP AI++G++LA RLF G ++LMDY
Sbjct  301  KTKPN-GKIIANDDDTTNVENIFAIGDCVDKRPELTPTAIKAGRLLARRLFNGDTKLMDY  359

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
            +++PTTVFTPIEYG++G SEE+AK +YG+D I VY+S F PL W+ +  + D   + K++
Sbjct  360  NSIPTTVFTPIEYGTIGLSEEDAKTKYGEDNIKVYYSIFTPLDWSYSDHKHDDKGHAKLI  419

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
                 D++VVG H LGP AGE+ QG A+A K   TKAN DD VGIHPT AE FTTL  +K
Sbjct  420  VNKADDERVVGFHYLGPHAGEVTQGFAIAFKFKATKANFDDVVGIHPTYAEEFTTLKNVK  479

Query  484  EDG  486
             +G
Sbjct  480  GEG  482


>ref|XP_001507796.1|  PREDICTED: similar to thioredoxin reductase 1 [Ornithorhynchus 
anatinus]
Length=621

 GENE ID: 100076415 LOC100076415 | similar to thioredoxin reductase 1
[Ornithorhynchus anatinus]

 Score =  512 bits (1319),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 266/485 (54%), Positives = 339/485 (69%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            +D+DL VIGGGSGGLAAAK AA  G +V + DFV P+P G  WGLGGTCVNVGCIPKKL+
Sbjct  135  FDYDLIVIGGGSGGLAAAKEAAKYGKKVMVLDFVTPTPLGNRWGLGGTCVNVGCIPKKLM  194

Query  68   HMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GW++  T  HNWE+M + V  YI SLNWGY+  LR   V  Y N
Sbjct  195  HQAALLGQALQDSRKYGWQVEETVKHNWESMTEAVQNYIGSLNWGYRVALRENKV-TYEN  253

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++  F+  + +K T+++GKE+  TA   LIATG RP   G PG  + CI+SDD+F     
Sbjct  254  AYGEFVGPHKIKATNQKGKENFYTAEKFLIATGERPRYLGIPGDKKYCISSDDLFSLPYC  313

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG KF+ 
Sbjct  314  PGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIK  373

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + +P K E+ E+   GK++V A+S+       ++  G ++TVL+AVGR  C   + L+N 
Sbjct  374  KFVPIKIEQIEEGMPGKLKVVAQST----DGQETIEGEYNTVLLAVGRDSCTRKIGLENV  429

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV   E TN+  IYAIGDV+EG LELTPVAIQ+G++LA RL+ G++   
Sbjct  430  GVKINEKTGKIPVTDEEQTNVPYIYAIGDVLEGKLELTPVAIQAGRLLARRLYSGSTVKC  489

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R +  CY K
Sbjct  490  DYDNVPTTVFTPLEYGACGFSEEKAAEKFGEENIEVYHSYFWPLEWTV-PSRDNNKCYAK  548

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FTTLT 
Sbjct  549  IICNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKEQLDSTIGIHPVCAEIFTTLTV  608

Query  482  IKEDG  486
             K  G
Sbjct  609  TKRSG  613


>ref|XP_001630291.1|  predicted protein [Nematostella vectensis]
 gb|EDO38228.1|  predicted protein [Nematostella vectensis]
Length=593

 GENE ID: 5509832 NEMVEDRAFT_v1g188544 | hypothetical protein
[Nematostella vectensis] (10 or fewer PubMed links)

 Score =  508 bits (1309),  Expect = 4e-142, Method: Compositional matrix adjust.
 Identities = 251/490 (51%), Positives = 334/490 (68%), Gaps = 13/490 (2%)

Query  3    PAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCI  62
            P  + Y++DL VIGGGSGGLA AK AA LG +VA+ DFVKP+P+GTTWGLGGTCVNVGCI
Sbjct  103  PPSASYEYDLIVIGGGSGGLACAKEAAQLGRKVAVLDFVKPTPKGTTWGLGGTCVNVGCI  162

Query  63   PKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNV  120
            PKKL+H +A   E   D+   GWE      HNWE++ + V  +I SLNWGY+ +LR  +V
Sbjct  163  PKKLMHQAALLGEALKDARLYGWEFDEKVKHNWESLREGVQNHIGSLNWGYRVQLREKSV  222

Query  121  KXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIF  180
              Y N+F  FID +T+K TDKRG E+I+TA   ++A G RP     PGA E  ITSDD+F
Sbjct  223  -TYKNAFGEFIDNHTIKATDKRGTETIMTAETFVLAMGLRPRYPNIPGAKEYGITSDDLF  281

Query  181  RRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHG  240
                 PG T+++GASY++LECAGF+A  G D TV+VRSILLRGFDQ MA++ G +ME HG
Sbjct  282  SLPYCPGTTVLIGASYVSLECAGFLAAMGLDVTVVVRSILLRGFDQQMAEKAGSFMETHG  341

Query  241  TKFVHEMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWL  297
             KF    +PTK E+ E+   GK+RV+ K         D      +TV+ A+GR  C   +
Sbjct  342  VKFKRPAVPTKVEQLEEGSPGKLRVHYKLEGGEEGHLDC-----NTVVFAIGRDACTTGI  396

Query  298  SLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGG  357
             L+  GV  NP   K+     E +++ NIYAIGD+++G LELTPVAIQ+G++L+ RL+  
Sbjct  397  GLEKVGVKLNPKNQKVIAGDNEQSSVPNIYAIGDILDGKLELTPVAIQAGRLLSRRLYRN  456

Query  358  ASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDA  416
             ++L DY NV TTVFTP+EYG++G SEE+A +++G + + VYH+ F+PL + + + R   
Sbjct  457  DTKLCDYINVATTVFTPLEYGAIGYSEEDAIQKFGQENVEVYHTLFQPLEYTVAQ-RSKD  515

Query  417  DCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETF  476
            DCY K++C     ++VVG H+LGP+AGE+ QG AVA K G TK + DDT+GIHPTC+ETF
Sbjct  516  DCYAKLICNKADSERVVGFHVLGPNAGEITQGYAVAFKCGATKEHFDDTIGIHPTCSETF  575

Query  477  TTLTQIKEDG  486
            T L   K  G
Sbjct  576  TLLDVTKRSG  585


>gb|ACL81230.1|  thioredoxin reductase 1 [Moneuplotes crassus]
Length=498

 Score =  507 bits (1305),  Expect = 1e-141, Method: Compositional matrix adjust.
 Identities = 258/481 (53%), Positives = 335/481 (69%), Gaps = 11/481 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DLFVIGGGSGGLA AK A   GA+VA+ADFVKP+P+GT W +GGTCVNVGCIPKKL+
Sbjct  15   YDYDLFVIGGGSGGLACAKVAQEAGAKVAVADFVKPTPKGTKWKVGGTCVNVGCIPKKLM  74

Query  68   HMSAHTAETAGDSAGLGWEL-TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
            H SA    +  D    GWE    SH+W  MI NV  +I  +N+GYK+++R   +K +   
Sbjct  75   HYSALLGNSYHDQVESGWEHEKPSHDWGKMITNVNNHIRGINFGYKADMRKRGIK-FHEK  133

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAPP  186
            FA+F+D +T++L DK+GK  ++T+ Y +IATGGRP     PGA E  ITSDDIF  K  P
Sbjct  134  FASFVDPHTVQLVDKKGKTEMITSNYFVIATGGRPLYPDIPGAKEHAITSDDIFWMKDNP  193

Query  187  GKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVHE  246
            GKTLVVGASY+ALECAGF+  FG + +V VRSI LRGFDQDMAQ+I K MEL G  F+ +
Sbjct  194  GKTLVVGASYVALECAGFLHHFGNEVSVCVRSIFLRGFDQDMAQKIAKDMELSGINFIRD  253

Query  247  MIPTKFEKTED-GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGVH  305
             +PTK EK E+ GK+  +      T+   ++   V DTVL A+GR      L+L NAG+ 
Sbjct  254  SVPTKIEKDEETGKLTCFL-----TVGGEETTVEV-DTVLFAIGRYAVTADLNLGNAGL-  306

Query  306  YNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDYH  365
                 GK   DK++ TN+DNIYAIGDV+ G LELTP AIQ+G++LA RLF G +  MD++
Sbjct  307  IAEKNGKFITDKYQKTNVDNIYAIGDVLHGKLELTPTAIQAGRLLADRLFAGGTTTMDFY  366

Query  366  NVPTTVFTPIEYGSVGSSEENAKEEYGDDLIVYHSFFKPLLWALNKD-RGDADCYMKVLC  424
            +VPTT+FTP+EYG VG SEE+A+EEYGD + VYH++F+PL W   K    + +CY+K++ 
Sbjct  367  DVPTTIFTPLEYGCVGYSEEDAREEYGDFIKVYHTYFQPLEWNFAKSIYKERNCYVKIIV  426

Query  425  ENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIKE  484
                + +V+G HIL P+AGE+ QG+A+A+K G TK  LD+ VGIHPT AE  T L   K 
Sbjct  427  NTADNDRVIGFHILCPNAGEITQGIAIAIKVGVTKPQLDNCVGIHPTIAEEMTNLHIDKA  486

Query  485  D  485
            D
Sbjct  487  D  487


>gb|AAH30028.1|  TXNRD3 protein [Homo sapiens]
Length=678

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  507 bits (1305),  Expect = 1e-141, Method: Compositional matrix adjust.
 Identities = 266/485 (54%), Positives = 332/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  192  YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  251

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE MI+ +  +ISSLNWGY+  LR   V  Y N
Sbjct  252  HQAALLGQALCDSRKFGWEYNQQVRHNWETMIKAIQNHISSLNWGYRLSLREKAV-AYVN  310

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  311  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  370

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  371  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  430

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  431  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  486

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  487  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  546

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  547  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  605

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  606  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  665

Query  482  IKEDG  486
             K  G
Sbjct  666  TKSSG  670


>ref|XP_516719.2|  PREDICTED: thioredoxin reductase 3 [Pan troglodytes]
Length=752

 GENE ID: 460662 TXNRD3 | thioredoxin reductase 3 [Pan troglodytes]

 Score =  506 bits (1303),  Expect = 2e-141, Method: Compositional matrix adjust.
 Identities = 266/488 (54%), Positives = 333/488 (68%), Gaps = 12/488 (2%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPK
Sbjct  263  DSAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPK  322

Query  65   KLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  
Sbjct  323  KLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-A  381

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NS+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F  
Sbjct  382  YVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSL  441

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG K
Sbjct  442  PYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVK  501

Query  243  FVHEMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSL  299
            F+ + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L
Sbjct  502  FLRKFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGL  557

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            +  GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG + 
Sbjct  558  EKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLARRLFGASL  617

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADC  418
               DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  C
Sbjct  618  EKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTC  676

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTT
Sbjct  677  YAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTT  736

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  737  LEITKSSG  744


>gb|AAD51325.1|AF171055_1  thioredoxin reductase TR2 [Homo sapiens]
Length=579

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  505 bits (1300),  Expect = 5e-141, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 331/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  91   YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  150

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  151  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  209

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  210  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  269

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  270  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  329

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  330  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  385

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  386  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  445

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  446  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  504

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  505  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  564

Query  482  IKEDG  486
             K  G
Sbjct  565  TKSSG  569


>gb|AAH50032.1|  TXNRD3 protein [Homo sapiens]
Length=681

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  505 bits (1300),  Expect = 5e-141, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 331/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  195  YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  254

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  255  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  313

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  314  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  373

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  374  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  433

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  434  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  489

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  490  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  549

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  550  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  608

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  609  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  668

Query  482  IKEDG  486
             K  G
Sbjct  669  TKSSG  673


>ref|XP_001130163.1|  PREDICTED: thioredoxin reductase 3 [Homo sapiens]
Length=752

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  504 bits (1299),  Expect = 6e-141, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 331/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  266  YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  325

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  326  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  384

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  385  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  444

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  445  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  504

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  505  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  560

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  561  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  620

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  621  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  679

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  680  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  739

Query  482  IKEDG  486
             K  G
Sbjct  740  TKSSG  744


>ref|XP_001129642.1|  PREDICTED: similar to TXNRD3 protein [Homo sapiens]
Length=752

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  504 bits (1298),  Expect = 7e-141, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 331/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  266  YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  325

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  326  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  384

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  385  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  444

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  445  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  504

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  505  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  560

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  561  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  620

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  621  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  679

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  680  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  739

Query  482  IKEDG  486
             K  G
Sbjct  740  TKSSG  744


>ref|NP_777050.1|  thioredoxin reductase 1 [Bos taurus]
 sp|O62768.3|TRXR1_BOVIN  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1
 gb|AAC13914.1|  thioredoxin reductase [Bos taurus]
Length=499

 GENE ID: 282388 TXNRD1 | thioredoxin reductase 1 [Bos taurus]
(10 or fewer PubMed links)

 Score =  504 bits (1297),  Expect = 9e-141, Method: Compositional matrix adjust.
 Identities = 271/492 (55%), Positives = 341/492 (69%), Gaps = 16/492 (3%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+P    YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVG
Sbjct  8    PEP----YDYDLIIIGGGSGGLAAAKEAAKYDKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+WE M + V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALRDSRNYGWNVEETVKHDWERMTEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  F+  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-TYENAYGEFVGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++M+ 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMQE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV AKS   T SD   E G ++TVL+A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVIAKS---TDSDQTIE-GEYNTVLLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+N GV  N   GKIPV + E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+
Sbjct  299  KIGLENVGVKINEKTGKIPVTEEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
            GG++   DY NVPTTVFTP+EYGS G SEE A E++G++ + VYHS+F PL W +   R 
Sbjct  359  GGSTVKCDYENVPTTVFTPLEYGSCGLSEEKAVEKFGEENVEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKVVCNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>sp|Q86VQ6.2|TRXR3_HUMAN  RecName: Full=Thioredoxin reductase 3; AltName: Full=Thioredoxin 
reductase TR2; AltName: Full=Thioredoxin and glutathione 
reductase
Length=754

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  504 bits (1297),  Expect = 9e-141, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 331/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  266  YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  325

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  326  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  384

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  385  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  444

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  445  PGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  504

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  505  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  560

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  561  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  620

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  621  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  679

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  680  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  739

Query  482  IKEDG  486
             K  G
Sbjct  740  TKSSG  744


>dbj|BAE26918.1|  unnamed protein product [Mus musculus]
Length=497

 GENE ID: 50493 Txnrd1 | thioredoxin reductase 1 [Mus musculus]
(Over 10 PubMed links)

 Score =  504 bits (1297),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 273/491 (55%), Positives = 341/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DP  S YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGC
Sbjct  6    DPPGS-YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGC  64

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++  T  H+WE M ++V ++I SLNWGY+  LR   
Sbjct  65   IPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKK  124

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  FI  + +  T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+
Sbjct  125  V-VYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDL  183

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  184  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEH  243

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G++RV A+S   T S+   E G F+TVL+AVGR  C   
Sbjct  244  GIKFIRQFVPTKIERIEAGTPGRLRVTAQS---TNSEETIE-GEFNTVLLAVGRDSCTRT  299

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+G
Sbjct  300  IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG  359

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +
Sbjct  360  GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDN  418

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K D++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  419  NKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEI  478

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  479  FTTLSVTKRSG  489


>ref|NP_001025933.2|  thioredoxin reductase 1 [Gallus gallus]
Length=499

 GENE ID: 418082 RCJMB04_23a5 | thioredoxin reductase 1 [Gallus gallus]
(10 or fewer PubMed links)

 Score =  504 bits (1297),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 264/485 (54%), Positives = 334/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL VIGGGSGGLAAAK AA    +V + DFV P+P G +WGLGGTCVNVGCIPKKL+
Sbjct  11   YDYDLIVIGGGSGGLAAAKEAAKYEKKVMVLDFVTPTPLGNSWGLGGTCVNVGCIPKKLM  70

Query  68   HMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GW+ T    HNW  M ++V  YI SLNWGY+  LR   V  Y N
Sbjct  71   HQAALLGQALQDSRKFGWQFTEEVKHNWMTMTESVQNYIGSLNWGYRVALREKKV-TYEN  129

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++  F+  +T+K T+KRG E + TA   LIATG RP   G PG  E CI+SDD+F     
Sbjct  130  AYGEFVGPHTVKATNKRGVEKLYTAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYC  189

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG+YME HG KF+ 
Sbjct  190  PGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQDMANKIGEYMEEHGIKFIR  249

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            E +P K E+ E+   G+++V AKS+ D     +     ++TVL+A+GR  C   + LD  
Sbjct  250  EFVPIKVEQIEEGTPGRLKVTAKSTKDDQVIEEE----YNTVLLAIGRDACTRKIGLDKV  305

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPVD  E TN+  IYAIGD+++  LELTPVAIQ+G++L  RL+ G++   
Sbjct  306  GVKINEKTGKIPVDDMEQTNVPYIYAIGDILQDRLELTPVAIQAGRLLVQRLYAGSTLKC  365

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG+ G SEENA +++G++ I VYHS F PL W +   R +  CY K
Sbjct  366  DYVNVPTTVFTPLEYGACGYSEENAIQKFGEENIEVYHSHFWPLEWTV-PSRDNNKCYAK  424

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  + +++V+G H+LGP+AGE+ QG A AMK G TK  LD T+GIHP CAE FTTL+ 
Sbjct  425  IICNIQDNQRVIGFHVLGPNAGEVTQGFAAAMKCGLTKDQLDSTIGIHPVCAEVFTTLSI  484

Query  482  IKEDG  486
             K  G
Sbjct  485  TKRSG  489


>gb|AAH85726.1|  Txnrd1 protein [Rattus norvegicus]
Length=578

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  503 bits (1296),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  88   APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP  147

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  148  KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  206

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  207  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  266

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  267  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  326

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  327  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  382

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  383  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  442

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  443  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  501

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  502  CYAKVVCNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  561

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  562  TLSVTKRSG  570


>gb|AAH37643.1|  Thioredoxin reductase 1 [Mus musculus]
 dbj|BAE40292.1|  unnamed protein product [Mus musculus]
 gb|EDL21375.1|  thioredoxin reductase 1, isoform CRA_a [Mus musculus]
 gb|EDL21376.1|  thioredoxin reductase 1, isoform CRA_a [Mus musculus]
Length=497

 GENE ID: 50493 Txnrd1 | thioredoxin reductase 1 [Mus musculus]
(Over 10 PubMed links)

 Score =  503 bits (1296),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 273/491 (55%), Positives = 341/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DP  S YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGC
Sbjct  6    DPPGS-YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGC  64

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++  T  H+WE M ++V ++I SLNWGY+  LR   
Sbjct  65   IPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKK  124

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  FI  + +  T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+
Sbjct  125  V-VYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDL  183

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  184  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEH  243

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G++RV A+S   T S+   E G F+TVL+AVGR  C   
Sbjct  244  GIKFIRQFVPTKIEQIEAGTPGRLRVTAQS---TNSEETIE-GEFNTVLLAVGRDSCTRT  299

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+G
Sbjct  300  IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG  359

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +
Sbjct  360  GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDN  418

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K D++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  419  NKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEI  478

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  479  FTTLSVTKRSG  489


>pdb|1H6V|A  Chain A, Mammalian Thioredoxin Reductase
 pdb|1H6V|B  Chain B, Mammalian Thioredoxin Reductase
 pdb|1H6V|C  Chain C, Mammalian Thioredoxin Reductase
 pdb|1H6V|D  Chain D, Mammalian Thioredoxin Reductase
 pdb|1H6V|E  Chain E, Mammalian Thioredoxin Reductase
 pdb|1H6V|F  Chain F, Mammalian Thioredoxin Reductase
Length=499

 Score =  503 bits (1296),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTNWGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  480

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  481  TLSVTKRSG  489


>pdb|3EAN|A  Chain A, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 pdb|3EAN|B  Chain B, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 pdb|3EAN|C  Chain C, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 9 more sequence titles
 pdb|3EAN|D  Chain D, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 pdb|3EAN|E  Chain E, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 pdb|3EAN|F  Chain F, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Reduced C-Terminal Tail
 pdb|3EAO|A  Chain A, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
 pdb|3EAO|B  Chain B, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
 pdb|3EAO|C  Chain C, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
 pdb|3EAO|D  Chain D, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
 pdb|3EAO|E  Chain E, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
 pdb|3EAO|F  Chain F, Crystal Structure Of Recombinant Rat Selenoprotein Thioredoxin 
Reductase 1 With Oxidized C-Terminal Tail
Length=499

 Score =  503 bits (1295),  Expect = 1e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  480

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  481  TLSVTKRSG  489


>gb|EDM17072.1|  thioredoxin reductase 1, isoform CRA_b [Rattus norvegicus]
 gb|EDM17073.1|  thioredoxin reductase 1, isoform CRA_b [Rattus norvegicus]
Length=497

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  503 bits (1295),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVVCNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  480

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  481  TLSVTKRSG  489


>ref|NP_113802.2|  thioredoxin reductase 1 [Rattus norvegicus]
Length=499

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  503 bits (1295),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVVCNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  480

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  481  TLSVTKRSG  489


>ref|NP_056577.2|  thioredoxin reductase 1 isoform 2 [Mus musculus]
 ref|NP_001035978.1|  thioredoxin reductase 1 isoform 2 [Mus musculus]
 ref|NP_001035979.1|  thioredoxin reductase 1 isoform 2 [Mus musculus]
 dbj|BAA86985.2|  thioredoxin reductase 1 [Mus musculus]
Length=499

 GENE ID: 50493 Txnrd1 | thioredoxin reductase 1 [Mus musculus]
(Over 10 PubMed links)

 Score =  503 bits (1295),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 273/491 (55%), Positives = 341/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DP  S YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGC
Sbjct  6    DPPGS-YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGC  64

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++  T  H+WE M ++V ++I SLNWGY+  LR   
Sbjct  65   IPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKK  124

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  FI  + +  T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+
Sbjct  125  V-VYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDL  183

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  184  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEH  243

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G++RV A+S   T S+   E G F+TVL+AVGR  C   
Sbjct  244  GIKFIRQFVPTKIEQIEAGTPGRLRVTAQS---TNSEETIE-GEFNTVLLAVGRDSCTRT  299

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+G
Sbjct  300  IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG  359

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +
Sbjct  360  GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDN  418

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K D++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  419  NKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEI  478

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  479  FTTLSVTKRSG  489


>gb|EDL21377.1|  thioredoxin reductase 1, isoform CRA_b [Mus musculus]
Length=611

 GENE ID: 50493 Txnrd1 | thioredoxin reductase 1 [Mus musculus]
(Over 10 PubMed links)

 Score =  503 bits (1295),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 273/491 (55%), Positives = 341/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DP  S YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGC
Sbjct  120  DPPGS-YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGC  178

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++  T  H+WE M ++V ++I SLNWGY+  LR   
Sbjct  179  IPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKK  238

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  FI  + +  T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+
Sbjct  239  V-VYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDL  297

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  298  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEH  357

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G++RV A+S   T S+   E G F+TVL+AVGR  C   
Sbjct  358  GIKFIRQFVPTKIEQIEAGTPGRLRVTAQS---TNSEETIE-GEFNTVLLAVGRDSCTRT  413

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+G
Sbjct  414  IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG  473

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +
Sbjct  474  GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDN  532

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K D++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  533  NKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEI  592

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  593  FTTLSVTKRSG  603


>ref|NP_001116145.1|  thioredoxin reductase 1 [Canis lupus familiaris]
Length=655

 GENE ID: 474536 TXNRD1 | thioredoxin reductase 1 [Canis lupus familiaris]

 Score =  503 bits (1294),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 263/486 (54%), Positives = 338/486 (69%), Gaps = 12/486 (2%)

Query  7    VYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKL  66
            VYD+DL +IGGGSGGLAAAK AA    ++ + DFV P+P+GT WGLGGTCVNVGCIPKKL
Sbjct  166  VYDYDLIIIGGGSGGLAAAKEAARYNKKIMVLDFVTPTPRGTRWGLGGTCVNVGCIPKKL  225

Query  67   LHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYF  124
            +H +A   +   DS   GW  E T  H+W+ M + V  +I SLNWGY+  LR   V  Y 
Sbjct  226  MHQAALLGQALQDSRNYGWSTEETVKHDWDKMTEAVQNHIGSLNWGYRVALREKKV-TYE  284

Query  125  NSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKA  184
            N++  F+  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+F    
Sbjct  285  NAYGQFVGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDREYCISSDDLFSLPY  344

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG KF+
Sbjct  345  CPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGVKFI  404

Query  245  HEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDN  301
             + +P K E+ E    G++RV A+S+S +    ++  G ++TVL+A+GR  C   + L+ 
Sbjct  405  RQFVPIKVEQIEAGTPGRLRVVAQSTSSS----ETIEGEYNTVLLAIGRDACTRKIGLET  460

Query  302  AGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRL  361
             GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+ G++  
Sbjct  461  VGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYAGSNVK  520

Query  362  MDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYM  420
             DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R +  CY 
Sbjct  521  CDYENVPTTVFTPLEYGACGLSEERAVEKFGEENIEVYHSYFWPLEWTI-PSRDNNKCYA  579

Query  421  KVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLT  480
            KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FTTL+
Sbjct  580  KVICNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKMQLDSTIGIHPICAEVFTTLS  639

Query  481  QIKEDG  486
              K  G
Sbjct  640  VTKRSG  645


>gb|AAD39929.1|AF133519_1  thioredoxin reductase 3 [Homo sapiens]
Length=577

 GENE ID: 114112 TXNRD3 | thioredoxin reductase 3 [Homo sapiens]
(10 or fewer PubMed links)

 Score =  503 bits (1294),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 264/485 (54%), Positives = 330/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGT+WGLGGTCVNVGCIPKKL+
Sbjct  89   YDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLM  148

Query  68   HMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GWE      HNWE M + +  +ISSLNWGY+  LR   V  Y N
Sbjct  149  HQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAV-AYVN  207

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            S+  F++ + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F     
Sbjct  208  SYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYC  267

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGK LVVGASY+ALECAGF+AGFG D TVMVRSILLRGFDQ+MA+++G YME HG KF+ 
Sbjct  268  PGKPLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLR  327

Query  246  EMIPT---KFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + IP    + EK   GK++V AKS+  T    ++  GV++TVL+A+GR  C   + L+  
Sbjct  328  KFIPVMVQQLEKGSPGKLKVLAKSTEGT----ETIEGVYNTVLLAIGRDSCTRKIGLEKI  383

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV+  E TN+  +YA+GD++E   ELTPVAIQSGK+LA RLFG +    
Sbjct  384  GVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKC  443

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG  G SEE A E Y  ++L +YH+ F PL W +   R +  CY K
Sbjct  444  DYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTV-AGRENNTCYAK  502

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C      +V+G HILGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTTL  
Sbjct  503  IICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEI  562

Query  482  IKEDG  486
             K  G
Sbjct  563  TKSSG  567


>gb|EDM17071.1|  thioredoxin reductase 1, isoform CRA_a [Rattus norvegicus]
Length=611

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  503 bits (1294),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 268/489 (54%), Positives = 337/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIP
Sbjct  121  APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP  180

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  181  KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  239

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  240  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  299

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  300  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  359

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  360  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  415

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  416  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  475

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  476  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  534

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  535  CYAKVVCNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  594

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  595  TLSVTKRSG  603


>ref|NP_001035988.1|  thioredoxin reductase 1 isoform 1 [Mus musculus]
 sp|Q9JMH6.3|TRXR1_MOUSE  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1
 gb|AAK01140.1|AF333036_1  thioredoxin reductase 1 [Mus musculus]
Length=613

 GENE ID: 50493 Txnrd1 | thioredoxin reductase 1 [Mus musculus]
(Over 10 PubMed links)

 Score =  503 bits (1294),  Expect = 2e-140, Method: Compositional matrix adjust.
 Identities = 273/491 (55%), Positives = 341/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DP  S YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGC
Sbjct  120  DPPGS-YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGC  178

Query  62   IPKKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW++  T  H+WE M ++V ++I SLNWGY+  LR   
Sbjct  179  IPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKK  238

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  FI  + +  T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+
Sbjct  239  V-VYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDL  297

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  298  FSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEH  357

Query  240  GTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +PTK E+ E    G++RV A+S   T S+   E G F+TVL+AVGR  C   
Sbjct  358  GIKFIRQFVPTKIEQIEAGTPGRLRVTAQS---TNSEETIE-GEFNTVLLAVGRDSCTRT  413

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+G
Sbjct  414  IGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYG  473

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +
Sbjct  474  GSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDN  532

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C  K D++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  533  NKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEI  592

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  593  FTTLSVTKRSG  603


>ref|XP_002219026.1|  hypothetical protein BRAFLDRAFT_122804 [Branchiostoma floridae]
 gb|EEA61430.1|  hypothetical protein BRAFLDRAFT_122804 [Branchiostoma floridae]
Length=596

 GENE ID: 7226406 BRAFLDRAFT_122804 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  502 bits (1293),  Expect = 3e-140, Method: Compositional matrix adjust.
 Identities = 268/485 (55%), Positives = 329/485 (67%), Gaps = 14/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL VIGGGSGGLAA+K A   G +V + DFVKPSP GTTWGLGGTCVNVGCIPKKL+
Sbjct  112  YDYDLIVIGGGSGGLAASKEAGKFGKKVLVCDFVKPSPIGTTWGLGGTCVNVGCIPKKLM  171

Query  68   HMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    +  DS   GWE++    HNW  M + +  YI SLNWGY+  LR   VK Y N
Sbjct  172  HQAALLGHSIEDSRKFGWEVSEEVKHNWHTMKEAIQNYIGSLNWGYRVALRDKGVK-YEN  230

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++A F+D +T+K  ++RGKE+ VTA   L+A G RP     PGA E  ITSDD+F     
Sbjct  231  AYAEFVDPHTIKTVNRRGKENTVTAERFLVAVGMRPRYPDIPGAKEYGITSDDLFSLPYC  290

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+ G G DTTVMVRSILLRGFDQ MA ++G YME  G KF+ 
Sbjct  291  PGKTLVVGASYVALECAGFLRGIGLDTTVMVRSILLRGFDQQMADKVGAYMEKGGMKFIR  350

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
              +PTK E+ E+   GK+RV        M D        +T+L  +GR  C   + L+ A
Sbjct  351  GCVPTKVERLEEGQPGKLRVTG------MQDGKEVVWEGNTILFGIGRDACTEGIHLEKA  404

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV +N   GKI  +  E TN  +IYAIGDV+EG LELTPVAIQ+GK+LA RL+GGA    
Sbjct  405  GVQFNTKNGKIYGNDVEQTNQPHIYAIGDVLEGKLELTPVAIQAGKLLAQRLYGGAQTKT  464

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG+ G SEE+A  +YG+D I VYHS F+PL W +     + DCY K
Sbjct  465  DYVNVPTTVFTPLEYGACGLSEEDAIAKYGEDNIEVYHSNFQPLEWTVPGHDVN-DCYAK  523

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            +LC  + +++VVG H+LGP+AGE+ QG   AMK G TKA LD T+GIHPT AE FTT+  
Sbjct  524  ILCNRQDNERVVGFHVLGPNAGEITQGYGAAMKCGMTKAQLDTTIGIHPTNAEIFTTMDI  583

Query  482  IKEDG  486
             K  G
Sbjct  584  TKGSG  588


>ref|NP_001120487.1|  hypothetical protein LOC100145605 [Xenopus (Silurana) tropicalis]
 gb|AAI61360.1|  LOC100145605 protein [Xenopus tropicalis]
Length=502

 GENE ID: 100145605 LOC100145605 | hypothetical protein LOC100145605
[Xenopus (Silurana) tropicalis] (10 or fewer PubMed links)

 Score =  502 bits (1292),  Expect = 4e-140, Method: Compositional matrix adjust.
 Identities = 256/483 (53%), Positives = 334/483 (69%), Gaps = 10/483 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            +D+DL VIGGGSGGLA AK AA  G +VA+ D+V+PSP+GT WG+GGTCVNVGCIPKKL+
Sbjct  18   HDYDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLM  77

Query  68   HMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    T  D+   GW+      HNW  M + V  Y+ SLNWG++ +L+   VK YFN
Sbjct  78   HQAALIGSTLKDAPHYGWDTPNEIQHNWGKMAKAVQNYVKSLNWGHRIQLQDKKVK-YFN  136

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGY-PGAGECCITSDDIFRRKA  184
              A+F+D + ++   K GKE++VTA  I+IATGGRP    + PGA E  ITSDD+F  K 
Sbjct  137  MKASFVDEHCIRGVTKAGKETLVTAENIVIATGGRPKYPTHVPGALEYGITSDDLFWLKE  196

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY++LECAGF+ G G DT  MVRSI LRGFDQ MA  +  YMELHGTKF+
Sbjct  197  SPGKTLVVGASYVSLECAGFLTGIGLDTAAMVRSIPLRGFDQQMAYLVTDYMELHGTKFL  256

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
             +  P+  EK ++GK+ V  K++      AD    ++DTV+ AVGR     +L+L+  GV
Sbjct  257  WKCTPSNVEKLKNGKLEVTWKNTESGKEGAD----IYDTVMWAVGRAAETQYLNLEKVGV  312

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
                D GKI V+  E T++ +IYAIGD+ EG  ELTP AI +GK+LA+RLF G++ LMDY
Sbjct  313  DVKSDTGKIIVNASEATSVPHIYAIGDITEGRPELTPTAIAAGKLLASRLFSGSAELMDY  372

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
             +VPTTVFTP+EYG VG SEE+AKE YGDD I V+H+F+KPL + +  +R  + CY+K++
Sbjct  373  DSVPTTVFTPLEYGCVGISEEDAKERYGDDNIEVFHAFYKPLEFIV-AERNGSQCYIKII  431

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
            C    D++++G+H  GP+AGE+IQG A+ +K G T   L  TVGIHPTCAE  T L   K
Sbjct  432  CLRTQDQRILGLHFTGPNAGEVIQGFALGIKCGATYHQLMRTVGIHPTCAEEVTKLHITK  491

Query  484  EDG  486
              G
Sbjct  492  RSG  494


>ref|XP_583261.3|  PREDICTED: thioredoxin reductase 3 [Bos taurus]
Length=578

 GENE ID: 319097 TXNRD3 | thioredoxin reductase 3 [Bos taurus]

 Score =  501 bits (1291),  Expect = 5e-140, Method: Compositional matrix adjust.
 Identities = 250/491 (50%), Positives = 334/491 (68%), Gaps = 15/491 (3%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            DPA   YD+DL VIGGGSGGL+ A+ AA LG +V + DFV PSP+GT WGLGGTCVNVGC
Sbjct  89   DPA---YDYDLIVIGGGSGGLSCAQEAAVLGRKVMVLDFVVPSPRGTAWGLGGTCVNVGC  145

Query  62   IPKKLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GWE +    H+W  M + + ++I SL+WG++  LR   
Sbjct  146  IPKKLMHQAALLGQALTDSRKFGWEYSQQVRHSWATMTEAIQSHIGSLSWGHRLALREKA  205

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y NSF  F++ + +K T+++G+E + TA   +IATG RP   G PG  E CITSDD+
Sbjct  206  V-TYVNSFGEFVEHHKVKATNEKGQEVLYTAAKFVIATGERPRYLGIPGDREYCITSDDL  264

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PG TLVVGASY+ALECAGF+AG G + TVMVRS+LLRGFDQ+MA+++G  M+  
Sbjct  265  FSLPYCPGATLVVGASYVALECAGFLAGLGLEVTVMVRSVLLRGFDQEMAEKVGASMQQL  324

Query  240  GTKFVHEMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G +F+ + +P + ++ E    G+++V AKS+  T    ++  G+++TVL+A+GR  C   
Sbjct  325  GVRFLRKFVPVEVQQLERGLPGRLKVVAKSTEGT----ETIEGIYNTVLLAIGRDSCTKK  380

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            L L+  GV+ +   GKIPV+  E T++  +YA+GDV+EG  +LTPVA+Q+GK+LA RLFG
Sbjct  381  LGLEKIGVNVSEKTGKIPVNDEEQTSVSYVYAVGDVLEGKPQLTPVAVQAGKLLARRLFG  440

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGD  415
            G S   DY NVPT VFTP+EYG  G SEE A E Y  ++L VYH+ F PL W +   R +
Sbjct  441  GRSEKCDYVNVPTVVFTPLEYGCCGYSEEKAGEVYQAENLNVYHTLFWPLEWTV-AGRDN  499

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY K++C    + +V+G H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E 
Sbjct  500  NTCYAKIICNKLDNDRVIGFHVLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEV  559

Query  476  FTTLTQIKEDG  486
            FTTL   K  G
Sbjct  560  FTTLEITKASG  570


>ref|XP_002219029.1|  hypothetical protein BRAFLDRAFT_122807 [Branchiostoma floridae]
 gb|EEA61433.1|  hypothetical protein BRAFLDRAFT_122807 [Branchiostoma floridae]
Length=596

 GENE ID: 7221374 BRAFLDRAFT_122807 | hypothetical protein
[Branchiostoma floridae] (10 or fewer PubMed links)

 Score =  500 bits (1288),  Expect = 1e-139, Method: Compositional matrix adjust.
 Identities = 266/485 (54%), Positives = 328/485 (67%), Gaps = 14/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL VIGGGSGGLAA+K A   G +V + DFVKPSP GTTWGLGGTCVNVGCIPKKL+
Sbjct  112  YDYDLIVIGGGSGGLAASKEAGKFGKKVLVCDFVKPSPIGTTWGLGGTCVNVGCIPKKLM  171

Query  68   HMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    +  DS   GWE++    HNW  M + +  YI SLNWGY+  LR   VK Y N
Sbjct  172  HQAALLGHSIEDSRKFGWEVSEEVKHNWHTMKEAIQNYIGSLNWGYRVALRDKGVK-YEN  230

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++A F+D +T+K  ++RGKE+  TA   L+A G RP     PGA E  ITSDD+F     
Sbjct  231  AYAEFVDPHTIKTVNRRGKENTATAERFLVAVGMRPRYPDIPGAKEYGITSDDLFSLPYC  290

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLV+GASY+ALECAGF+ G G DTTVMVRSILLRGFDQ MA ++G YME  G KF+ 
Sbjct  291  PGKTLVIGASYVALECAGFLRGIGLDTTVMVRSILLRGFDQQMADKVGAYMEKGGMKFIR  350

Query  246  EMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
              +PTK E+ E+   GK+RV        M D        +T+L  +GR  C   + L+ A
Sbjct  351  GCVPTKVERLEEGQPGKLRVTG------MQDGKEVVWEGNTILFGIGRDACTEGIHLEKA  404

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV +N   GKI  +  E TN  +IYAIGDV+EG LELTPVAIQ+GK+LA RL+GGA    
Sbjct  405  GVQFNTKNGKIYGNDVEQTNQPHIYAIGDVLEGKLELTPVAIQAGKLLAQRLYGGAQTKT  464

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG+ G SEE+A  +YG+D I VYHS F+PL W +     + DCY K
Sbjct  465  DYINVPTTVFTPLEYGACGLSEEDAIAKYGEDNIEVYHSNFQPLEWTVPGHDVN-DCYAK  523

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            +LC  + +++VVG H+LGP+AGE+ QG   AMK G TKA LD T+GIHPT AE FTT+  
Sbjct  524  ILCNRQDNERVVGFHVLGPNAGEITQGYGAAMKCGMTKAQLDTTIGIHPTNAEIFTTMDI  583

Query  482  IKEDG  486
             K  G
Sbjct  584  TKGSG  588


>gb|EAW97743.1|  thioredoxin reductase 1 [Homo sapiens]
 gb|EAW97744.1|  thioredoxin reductase 1 [Homo sapiens]
Length=623

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  500 bits (1287),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  130  PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  189

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  190  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  249

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  250  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  308

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  309  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  368

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  369  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  424

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  425  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  484

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  485  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  543

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  544  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  603

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  604  VFTTLSVTKRSG  615


>ref|NP_001116141.1|  thioredoxin reductase 1 [Pan troglodytes]
Length=499

 GENE ID: 467112 TXNRD1 | thioredoxin reductase 1 [Pan troglodytes]

 Score =  499 bits (1286),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 266/492 (54%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPESYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TVL+A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVLLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>emb|CAA04503.1|  thioredoxin reductase [Homo sapiens]
 gb|AAV38446.1|  thioredoxin reductase 1 [Homo sapiens]
 gb|AAZ67916.1|  thioredoxin reductase 1 [Homo sapiens]
 dbj|BAG35193.1|  unnamed protein product [Homo sapiens]
Length=497

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1285),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>gb|AAH56136.1|  Txnrd2 protein [Xenopus laevis]
Length=502

 GENE ID: 379744 txnrd2 | thioredoxin reductase 2 [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  499 bits (1285),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 255/483 (52%), Positives = 333/483 (68%), Gaps = 10/483 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            +D+DL VIGGGSGGLA AK AA  G +VA+ D+V+PSP+GT WG+GGTCVNVGCIPKKL+
Sbjct  18   HDYDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLM  77

Query  68   HMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    T  D+   GW       H+W  M   V  Y+ SLNWG++ +L+   VK YFN
Sbjct  78   HQAALIGSTMKDAPHYGWGTPYEIQHDWGKMAGAVQNYVKSLNWGHRIQLQDKKVK-YFN  136

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGY-PGAGECCITSDDIFRRKA  184
              A F+D + ++   K GKE++VTA+ I+IATGGRP    + PGA E  ITSDD+F  K 
Sbjct  137  LKANFVDEHCIRGVTKAGKETLVTAQNIVIATGGRPKYPTHVPGALEYGITSDDLFWLKE  196

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY++LECAGF+ G G +TT MVRSI LRGFDQ MA  +  YME HGTKF+
Sbjct  197  SPGKTLVVGASYVSLECAGFLTGIGLNTTAMVRSIPLRGFDQQMAYLVADYMESHGTKFL  256

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
             +  P+  EK ++GK++V  K++       D    ++DTV+ AVGR     +L+L+  GV
Sbjct  257  WKCTPSHVEKLKNGKLQVTWKNTQSGKEGVD----IYDTVMWAVGRAAETQYLNLEKVGV  312

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
               P+ GKI VD  E T++ +IYAIGD+ EG  ELTP AI +GK+LA RLF G++ LMDY
Sbjct  313  KIKPETGKIIVDASEATSVPHIYAIGDITEGRPELTPTAIAAGKLLAIRLFSGSAELMDY  372

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
             +VPTTVFTP+EYG VG SEE AKE YGDD I V+H+F+KPL + +  +R  + CY+K++
Sbjct  373  DSVPTTVFTPLEYGCVGISEEEAKERYGDDNIEVFHAFYKPLEFTV-AERDASQCYIKII  431

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
            C  K D++++G+H+ GP+AGE+IQG A+ +K G T   L  TVGIHPTCAE  T L   K
Sbjct  432  CLRKHDQRILGLHLTGPNAGEVIQGFALGIKCGATYPQLMCTVGIHPTCAEEVTKLHITK  491

Query  484  EDG  486
              G
Sbjct  492  RSG  494


>dbj|BAH11961.1|  unnamed protein product [Homo sapiens]
Length=547

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1285),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  54   PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  113

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  114  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  173

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  174  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  232

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  233  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  292

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  293  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  348

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  349  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  408

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  409  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  467

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  468  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  527

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  528  VFTTLSVTKRSG  539


>gb|EAW97745.1|  thioredoxin reductase 1 [Homo sapiens]
 dbj|BAH14140.1|  unnamed protein product [Homo sapiens]
Length=647

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1285),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  154  PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  213

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  214  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  273

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  274  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  332

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  333  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  392

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  393  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  448

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  449  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  508

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  509  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  567

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  568  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  627

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  628  VFTTLSVTKRSG  639


>emb|CAG38744.1|  TXNRD1 [Homo sapiens]
Length=497

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1285),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  RIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>sp|Q5NVA2.3|TRXR1_PONAB  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1
Length=499

 GENE ID: 100174180 TXNRD1 | thioredoxin reductase 1 [Pongo abelii]

 Score =  499 bits (1285),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPESYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTL+VGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLIVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TVL+A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVLLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>ref|NP_003321.3|  thioredoxin reductase 1 isoform 1 [Homo sapiens]
Length=551

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1284),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  56   PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  115

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  116  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  175

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  176  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  234

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  235  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  294

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  295  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  350

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  351  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  410

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  411  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  469

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  470  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  529

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  530  VFTTLSVTKRSG  541


>dbj|BAA13674.1|  KM-102-derived reductase-like factor [Homo sapiens]
Length=549

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1284),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  56   PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  115

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  116  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  175

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  176  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  234

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  235  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  294

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  295  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  350

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  351  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  410

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  411  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  469

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  470  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  529

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  530  VFTTLSVTKRSG  541


>ref|NP_001080052.1|  thioredoxin reductase 2 [Xenopus laevis]
Length=504

 GENE ID: 379744 txnrd2 | thioredoxin reductase 2 [Xenopus laevis]
(10 or fewer PubMed links)

 Score =  499 bits (1284),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 255/483 (52%), Positives = 333/483 (68%), Gaps = 10/483 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            +D+DL VIGGGSGGLA AK AA  G +VA+ D+V+PSP+GT WG+GGTCVNVGCIPKKL+
Sbjct  18   HDYDLLVIGGGSGGLACAKQAAQFGKKVAVFDYVEPSPRGTKWGIGGTCVNVGCIPKKLM  77

Query  68   HMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    T  D+   GW       H+W  M   V  Y+ SLNWG++ +L+   VK YFN
Sbjct  78   HQAALIGSTMKDAPHYGWGTPYEIQHDWGKMAGAVQNYVKSLNWGHRIQLQDKKVK-YFN  136

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGY-PGAGECCITSDDIFRRKA  184
              A F+D + ++   K GKE++VTA+ I+IATGGRP    + PGA E  ITSDD+F  K 
Sbjct  137  LKANFVDEHCIRGVTKAGKETLVTAQNIVIATGGRPKYPTHVPGALEYGITSDDLFWLKE  196

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY++LECAGF+ G G +TT MVRSI LRGFDQ MA  +  YME HGTKF+
Sbjct  197  SPGKTLVVGASYVSLECAGFLTGIGLNTTAMVRSIPLRGFDQQMAYLVADYMESHGTKFL  256

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
             +  P+  EK ++GK++V  K++       D    ++DTV+ AVGR     +L+L+  GV
Sbjct  257  WKCTPSHVEKLKNGKLQVTWKNTQSGKEGVD----IYDTVMWAVGRAAETQYLNLEKVGV  312

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
               P+ GKI VD  E T++ +IYAIGD+ EG  ELTP AI +GK+LA RLF G++ LMDY
Sbjct  313  KIKPETGKIIVDASEATSVPHIYAIGDITEGRPELTPTAIAAGKLLAIRLFSGSAELMDY  372

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
             +VPTTVFTP+EYG VG SEE AKE YGDD I V+H+F+KPL + +  +R  + CY+K++
Sbjct  373  DSVPTTVFTPLEYGCVGISEEEAKERYGDDNIEVFHAFYKPLEFTV-AERDASQCYIKII  431

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
            C  K D++++G+H+ GP+AGE+IQG A+ +K G T   L  TVGIHPTCAE  T L   K
Sbjct  432  CLRKHDQRILGLHLTGPNAGEVIQGFALGIKCGATYPQLMCTVGIHPTCAEEVTKLHITK  491

Query  484  EDG  486
              G
Sbjct  492  RSG  494


>ref|NP_877393.1|  thioredoxin reductase 1 isoform 2 [Homo sapiens]
 ref|NP_877419.1|  thioredoxin reductase 1 isoform 2 [Homo sapiens]
 ref|NP_877420.1|  thioredoxin reductase 1 isoform 2 [Homo sapiens]
 gb|AAH18122.2|  Thioredoxin reductase 1 [Homo sapiens]
Length=499

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1284),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>ref|NP_001087240.1|  thioredoxin reductase 1 isoform 3 [Homo sapiens]
 sp|Q16881.3|TRXR1_HUMAN  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1; AltName: Full=KM-102-derived 
reductase-like factor; AltName: Full=Gene associated 
with retinoid-IFN-induced mortality 12 protein; Short=GRIM-12
Length=649

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  499 bits (1284),  Expect = 3e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  154  PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  213

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  214  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  273

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  274  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  332

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  333  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  392

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  393  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  448

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  449  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  508

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  509  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  567

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  568  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  627

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  628  VFTTLSVTKRSG  639


>pdb|2CFY|A  Chain A, Crystal Structure Of Human Thioredoxin Reductase 1
 pdb|2CFY|B  Chain B, Crystal Structure Of Human Thioredoxin Reductase 1
 pdb|2CFY|C  Chain C, Crystal Structure Of Human Thioredoxin Reductase 1
 pdb|2CFY|D  Chain D, Crystal Structure Of Human Thioredoxin Reductase 1
 pdb|2CFY|E  Chain E, Crystal Structure Of Human Thioredoxin Reductase 1
 pdb|2CFY|F  Chain F, Crystal Structure Of Human Thioredoxin Reductase 1
Length=521

 Score =  498 bits (1283),  Expect = 4e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  26   PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  85

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  86   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  145

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  146  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  204

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  205  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  264

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  265  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  320

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  321  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  380

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  381  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  439

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  440  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  499

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  500  VFTTLSVTKRSG  511


>pdb|2J3N|A  Chain A, X-Ray Structure Of Human Thioredoxin Reductase 1
 pdb|2J3N|B  Chain B, X-Ray Structure Of Human Thioredoxin Reductase 1
 pdb|2J3N|C  Chain C, X-Ray Structure Of Human Thioredoxin Reductase 1
 pdb|2J3N|D  Chain D, X-Ray Structure Of Human Thioredoxin Reductase 1
 pdb|2J3N|E  Chain E, X-Ray Structure Of Human Thioredoxin Reductase 1
 pdb|2J3N|F  Chain F, X-Ray Structure Of Human Thioredoxin Reductase 1
Length=519

 Score =  498 bits (1282),  Expect = 5e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  24   PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  83

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  84   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  143

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  144  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  202

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  203  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  262

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  263  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  318

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  319  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  378

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  379  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  437

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  438  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  497

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  498  VFTTLSVTKRSG  509


>ref|NP_001127133.1|  thioredoxin reductase 1 [Pongo abelii]
 emb|CAI30275.1|  hypothetical protein [Pongo abelii]
Length=499

 GENE ID: 100174180 TXNRD1 | thioredoxin reductase 1 [Pongo abelii]

 Score =  498 bits (1281),  Expect = 7e-139, Method: Compositional matrix adjust.
 Identities = 265/492 (53%), Positives = 337/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPESYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V   I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNRIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTL+VGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLIVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TVL+A+GR  C  
Sbjct  243  HGIKFIRQFVPVKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVLLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVAKRSG  489


>gb|AAC69621.1|  thioredoxin reductase GRIM-12 [Homo sapiens]
Length=497

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  498 bits (1281),  Expect = 7e-139, Method: Compositional matrix adjust.
 Identities = 264/492 (53%), Positives = 338/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G + TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLNVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>ref|NP_001131081.1|  thioredoxin reductase 1 [Equus caballus]
Length=499

 GENE ID: 100067923 TXNRD1 | thioredoxin reductase 1 [Equus caballus]

 Score =  498 bits (1281),  Expect = 8e-139, Method: Compositional matrix adjust.
 Identities = 266/485 (54%), Positives = 334/485 (68%), Gaps = 12/485 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT WGLGGTCVNVGCIPKKL+
Sbjct  11   YDYDLIIIGGGSGGLAAAKEAAKYNKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLM  70

Query  68   HMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A   +   DS   GW  E    H+WE M + V  +I SLNWGY+  LR   V  Y N
Sbjct  71   HQAALLGQALRDSRNYGWNVEEMVKHDWEKMTEAVQNHIGSLNWGYRVALREKKV-TYEN  129

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++  FI  + +K T+ +GKE I +A   LIATG RP     PG  E CI+SDD+F     
Sbjct  130  AYGQFIGPHRIKTTNNKGKEKIYSAEKFLIATGERPRYLDIPGDKEYCISSDDLFSLPYC  189

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG KF+ 
Sbjct  190  PGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGVKFIK  249

Query  246  EMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            + +P K E+ E    G++RV A+S   T  D   E G ++TVL+A+GR  C   + L+  
Sbjct  250  QFVPIKVEQIEAGTPGQLRVVAQS---TKGDETIE-GEYNTVLLAIGRDACTRKIGLETV  305

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG++   
Sbjct  306  GVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKC  365

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG+ G SEENA E++G++ I VYHS+F PL W +   R +  CY K
Sbjct  366  DYENVPTTVFTPLEYGACGLSEENAVEKFGEENIEVYHSYFWPLEWTI-PSRDNNKCYAK  424

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FTTL+ 
Sbjct  425  IICNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSV  484

Query  482  IKEDG  486
             K  G
Sbjct  485  TKRSG  489


>ref|XP_001365687.1|  PREDICTED: similar to Thioredoxin reductase 1, cytoplasmic (TR) 
(TR1) [Monodelphis domestica]
Length=497

 GENE ID: 100015072 LOC100015072 | similar to Thioredoxin reductase 1,
cytoplasmic (TR) (TR1) [Monodelphis domestica]

 Score =  497 bits (1279),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 263/491 (53%), Positives = 339/491 (69%), Gaps = 13/491 (2%)

Query  2    DPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGC  61
            +P E+ YD+DL +IGGGSGGLAAAK AA  G ++ + DFV P+P G  WGLGGTCVNVGC
Sbjct  6    EPPEA-YDYDLIIIGGGSGGLAAAKEAARYGKKILVLDFVTPTPLGNRWGLGGTCVNVGC  64

Query  62   IPKKLLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTN  119
            IPKKL+H +A   +   DS   GW+L+    HNWE+M + V  YI SLNWGY+  LR   
Sbjct  65   IPKKLMHQAALLGQALQDSRKYGWQLSEEVKHNWESMTEAVQNYIGSLNWGYRVALRENR  124

Query  120  VKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDI  179
            V  Y N++  F+  + +K T+ +GKE   TA   LIATG RP   G PG  E CI+SDD+
Sbjct  125  V-TYENAYGEFVGPHKIKATNNKGKEKFYTAERFLIATGERPRYPGIPGDKEYCISSDDL  183

Query  180  FRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH  239
            F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME H
Sbjct  184  FSLSYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEDH  243

Query  240  GTKFVHEMIPTKFEKTED---GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGW  296
            G KF+ + +P K E+ ++   G +RV A+S+       ++  G ++TVL+A+GR  C   
Sbjct  244  GIKFIKKFVPIKIEQIKEGTPGTLRVVAQST----DGKETIEGEYNTVLLAIGRDSCTRK  299

Query  297  LSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFG  356
            + L+  GV  N   GKIPV+  E TN+  IYAIGDV+E  LELTPVAIQ+G++LA RL+ 
Sbjct  300  IGLETVGVKINEKTGKIPVNDEEQTNVPYIYAIGDVLEDKLELTPVAIQAGRLLARRLYA  359

Query  357  GASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGD  415
            G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R +
Sbjct  360  GSTIKCDYDNVPTTVFTPLEYGACGLSEERAVEKFGEENIEVYHSYFWPLEWTI-PSRDN  418

Query  416  ADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAET  475
              CY KV+C  + +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE 
Sbjct  419  NKCYAKVICHVRDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKNQLDSTIGIHPVCAEV  478

Query  476  FTTLTQIKEDG  486
            FTTL+  K  G
Sbjct  479  FTTLSVTKRSG  489


>gb|AAL15432.1|  thioredoxin reductase 1 [Homo sapiens]
Length=647

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  496 bits (1277),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 264/492 (53%), Positives = 337/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  154  PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  213

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  214  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  273

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  274  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAESFLIATGERPRYLGIPGDKEYCISSDD  332

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G   TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  333  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLGVTVMVRSILLRGFDQDMANKIGEHMEE  392

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  393  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  448

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  449  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  508

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  509  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  567

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  568  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  627

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  628  VFTTLSVTKRSG  639


>gb|AAB35418.1|  thioredoxin reductase [Homo sapiens]
 emb|CAA62629.1|  thioredoxin reductase (NADPH) [Homo sapiens]
Length=497

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  496 bits (1276),  Expect = 2e-138, Method: Compositional matrix adjust.
 Identities = 264/492 (53%), Positives = 337/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAESFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G   TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLGVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>gb|ACL81231.1|  thioredoxin reductase 2 [Moneuplotes crassus]
Length=508

 Score =  495 bits (1274),  Expect = 4e-138, Method: Compositional matrix adjust.
 Identities = 256/479 (53%), Positives = 329/479 (68%), Gaps = 15/479 (3%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQG---TTWGLGGTCVNVGCIPK  64
            YD+DLFVIGGGSGGLA AK A   GA+VA+ADFVKPSP G    TWG+GGTCVNVGCIPK
Sbjct  21   YDYDLFVIGGGSGGLACAKAAQECGAKVAVADFVKPSPHGYGVVTWGVGGTCVNVGCIPK  80

Query  65   KLLHMSAHTAETAGDSAGLGWELTA-SHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            KLLH SA+  E   D A  GW+     H+W  MI N+  +I ++N+  K++LR   +K +
Sbjct  81   KLLHYSANLGEAYVDRASSGWDHEKPKHDWGKMISNINNHIRAINFSIKTDLRKRGIK-F  139

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
            +   A+F D +T++L +K+GK  +VTA +I+IATGGRP     PGA E  ITSDDIF  K
Sbjct  140  YEKLASFADPHTIQLLNKKGKTELVTANHIVIATGGRPLYPDIPGAKEYGITSDDIFWLK  199

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELH-GTK  242
              PGKTLV+GASYIALECAGF+  FG D +V VRS+ LRGFDQDMA  + K ME H G K
Sbjct  200  KNPGKTLVIGASYIALECAGFLHSFGNDVSVCVRSVFLRGFDQDMANMLAKDMEEHGGVK  259

Query  243  FVHEMIPTKFEKTED-GKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDN  301
            F+   IPTK EK E+ GK+  Y  S  + ++         DTVL A+GR      L+L+N
Sbjct  260  FIKNSIPTKIEKDEETGKLICYLTSREEEITIE------VDTVLFAIGRYAVTKDLNLEN  313

Query  302  AGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRL  361
            AG+    + GK   D+F+ TN++NIYAIGDV+ G LELTP AIQ+GK+LA RL+ G +  
Sbjct  314  AGLKVESN-GKFITDEFQQTNVENIYAIGDVIHGKLELTPTAIQTGKLLARRLYAGETTT  372

Query  362  MDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLIVYHSFFKPLLWALNKD-RGDADCYM  420
            MD+ ++PTT+FTP+EYG VG SEE AKE+YGD + VYH++FKPL W   K      +CY+
Sbjct  373  MDFCDIPTTIFTPLEYGCVGYSEEEAKEKYGDAIKVYHTYFKPLEWNYAKSIYKYRNCYV  432

Query  421  KVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTL  479
            KV+     + +V+G H+L P+AGE+ QG+A+A+K G TK  LD+ VGIHPT AE  T L
Sbjct  433  KVIINTTENDRVIGYHLLAPNAGEITQGIAIAIKIGLTKHKLDNCVGIHPTVAEEVTDL  491


>gb|EEB11260.1|  thioredoxin reductase, putative [Pediculus humanus corporis]
Length=802

 Score =  494 bits (1273),  Expect = 5e-138, Method: Compositional matrix adjust.
 Identities = 265/485 (54%), Positives = 339/485 (69%), Gaps = 16/485 (3%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
            S YD+DL V+GGGSGGLAAAK AA LG  VAL DFVKP+P GTTWGLGGTCVNVGCIPKK
Sbjct  315  SQYDYDLVVVGGGSGGLAAAKEAATLGRTVALCDFVKPTPMGTTWGLGGTCVNVGCIPKK  374

Query  66   LLHMSAHTAETAGDSAGLGWELTAS---HNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            L+H ++  AE   DS+  GW    S   H WE M++NV  YI SLN+GY+ EL    VK 
Sbjct  375  LMHQASIHAENHHDSSSFGWNFHTSDGHHTWETMVENVQNYIKSLNFGYRKELNKRKVK-  433

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y N++A F+  + LKLT+K+G+ S V+A+ I+IA GGRP     PGA E CITSDD+F  
Sbjct  434  YLNAYAEFVAPHKLKLTNKKGEVSEVSAKDIIIAVGGRPAYPNVPGAKEFCITSDDLFSL  493

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
              PPGKTL+VGASYIALEC GF+ G GYD T+MVRSILLRGFD+ +A  IG++ME  G K
Sbjct  494  SKPPGKTLIVGASYIALECGGFLKGLGYDVTIMVRSILLRGFDRQIADLIGEHMEKIGIK  553

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGV--FDTVLMAVGRTGCAGWLSLD  300
            FV E  P  F KT +GK++V AKS          E  V  FDTV++A+GR  C G L L+
Sbjct  554  FVKEYEPIGFNKTNEGKIKVAAKSKK------GDEIVVSGFDTVVLAIGREACTGKLGLE  607

Query  301  N-AGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            N   +  NP   KI VD+FE +++ ++YAIGDV++G  ELTPVAI +GK LA R+ G  +
Sbjct  608  NLPNLKINPKNKKIIVDEFERSSVPHVYAIGDVIDGKPELTPVAIHAGKYLAQRICGVHN  667

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDADC  418
            +  +Y  VPTTVFTP+EYG+VG SEE A   +G ++++VYH+ FKPL  AL+  R D   
Sbjct  668  KTTNYKQVPTTVFTPLEYGTVGLSEEEAFNIFGKENIVVYHNAFKPLEHALS--REDTLG  725

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    ++ VVG H+L P+AGE+ QG A+A+K    K++ DD +GIHPTCAE FTT
Sbjct  726  YAKLICVKSLEELVVGFHVLSPNAGEITQGYAIALKLNAKKSDFDDLIGIHPTCAEIFTT  785

Query  479  LTQIK  483
            L+++K
Sbjct  786  LSRVK  790


>ref|NP_999319.1|  thioredoxin reductase 1 [Sus scrofa]
 sp|Q9MYY8.3|TRXR1_PIG  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1
 gb|AAF78791.1|AF277894_1  redox enzyme thioredoxin reductase [Sus scrofa]
Length=499

 GENE ID: 397299 TXNRD1 | thioredoxin reductase 1 [Sus scrofa]
(10 or fewer PubMed links)

 Score =  494 bits (1272),  Expect = 9e-138, Method: Compositional matrix adjust.
 Identities = 262/487 (53%), Positives = 334/487 (68%), Gaps = 12/487 (2%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
             +YD+DL +IGGGSGGLAAAK AA    RV + DFV P+P GT WGLGGTCVNV CIPKK
Sbjct  9    EMYDYDLIIIGGGSGGLAAAKEAARFNKRVMVLDFVTPTPLGTRWGLGGTCVNVSCIPKK  68

Query  66   LLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A   +   DS   GW  E T  H+WE M + V  +I SLNWGY+  LR   V  Y
Sbjct  69   LMHQAALLGQALRDSRNYGWNVEETIKHDWERMTEAVQNHIGSLNWGYRVALREKKV-TY  127

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             N++  F+  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+F   
Sbjct  128  ENAYGQFVGPHRIKATNNKGKEKIYSAEKFLIATGERPRYLGIPGDKEYCISSDDLFSLP  187

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG KF
Sbjct  188  YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKF  247

Query  244  VHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLD  300
            + + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C   + L+
Sbjct  248  IRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTRKIGLE  303

Query  301  NAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASR  360
              GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+ G++ 
Sbjct  304  TVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTV  363

Query  361  LMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCY  419
              DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R +  CY
Sbjct  364  KCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRDNNKCY  422

Query  420  MKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTL  479
             K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FTTL
Sbjct  423  AKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTL  482

Query  480  TQIKEDG  486
            +  K  G
Sbjct  483  SVTKRSG  489


>ref|XP_001744219.1|  hypothetical protein [Monosiga brevicollis MX1]
 gb|EDQ90922.1|  predicted protein [Monosiga brevicollis MX1]
Length=506

 GENE ID: 5889498 MONBRDRAFT_20369 | hypothetical protein
[Monosiga brevicollis MX1]

 Score =  494 bits (1271),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 256/482 (53%), Positives = 335/482 (69%), Gaps = 12/482 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            +D+DL V+GGGSGGLAA+K AA+LGA+ A+ DFV+PSPQGTTWGLGGTCVNVGCIPKKL+
Sbjct  26   FDYDLVVVGGGSGGLAASKEAASLGAKTAVLDFVQPSPQGTTWGLGGTCVNVGCIPKKLM  85

Query  68   HMSAHTAETAGDSAGLGWELTASH--NWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +A    T  D+   GW+L      NW  +++ V  +I SLNWGY+  LR  NV  Y N
Sbjct  86   HQAAIIGHTIEDATSFGWDLQRPEKPNWSTLVEGVQNHIRSLNWGYRVALRDKNV-TYLN  144

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            ++ + +D +T+   +KRGKE ++TA  I++  GGRP     PGA E  ITSDDIF     
Sbjct  145  AYGSLLDAHTINTVNKRGKEQVITADKIILCPGGRPRYPDIPGAKEFGITSDDIFSLDRE  204

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHG-TKFV  244
            PGKTLV+GASY+ALECAGF+A FGYDTTVMVRSILLRGFD ++AQ+IG +ME H   KFV
Sbjct  205  PGKTLVIGASYVALECAGFLAAFGYDTTVMVRSILLRGFDSEIAQKIGDHMERHAHVKFV  264

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
             +  P + EK EDG++ V+   + + +SD       FDTVL A+GR  C   + LD AGV
Sbjct  265  RQATPDRIEKREDGRLVVHYTQNGEAVSDE------FDTVLFAIGRDACTSTMGLDKAGV  318

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
              N   GK+  ++ + TN+ NIYAIGDV+EG  ELTPVAIQ+GK+LA RL+G ++ LMDY
Sbjct  319  QLNERNGKVVANEADQTNVPNIYAIGDVLEGKPELTPVAIQAGKLLARRLYGQSAALMDY  378

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLIVYHSFFKPLLWALNKDRGDADCYMKVLC  424
             NV TTVFTP+EYG  G SE++A +++G+D+ V+H  F PL W +   R +  C+ K++ 
Sbjct  379  QNVCTTVFTPLEYGCCGFSEDDALDQFGEDIEVFHQSFTPLEWTV-PHRPENVCFCKLVV  437

Query  425  ENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIKE  484
            +   D +V+G+H LGP+AGE+ QG  +A+K   TKA  DD VGIHPT AET TT+   K 
Sbjct  438  QKSTD-RVLGLHFLGPNAGEVTQGFGMALKLKATKAQFDDLVGIHPTVAETLTTMDITKA  496

Query  485  DG  486
             G
Sbjct  497  SG  498


>gb|AAF15900.1|AF208018_1  thioredoxin reductase [Homo sapiens]
Length=497

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  494 bits (1271),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 263/492 (53%), Positives = 336/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK  A  G +V + DF  P+P GT WGLGGTCVNVG
Sbjct  4    PEDLPKSYDYDLIIIGGGSGGLAAAKEPAQYGKKVMVLDFGTPTPLGTRWGLGGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>ref|XP_002108982.1|  hypothetical protein TRIADDRAFT_19325 [Trichoplax adhaerens]
 gb|EDV29780.1|  hypothetical protein TRIADDRAFT_19325 [Trichoplax adhaerens]
Length=489

 GENE ID: 6749456 TRIADDRAFT_19325 | hypothetical protein [Trichoplax adhaerens]
(10 or fewer PubMed links)

 Score =  493 bits (1268),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 245/484 (50%), Positives = 329/484 (67%), Gaps = 6/484 (1%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
             S Y +DL V+GGGSGGLA +K AA  G  VAL DFVKP+P G +WGLGGTCVNVGCIPK
Sbjct  2    HSEYSYDLIVVGGGSGGLACSKEAAEQGLTVALLDFVKPTPLGCSWGLGGTCVNVGCIPK  61

Query  65   KLLHMSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H ++   E+  D++  GWE+    SH+WE M  NV  +I S+N+GY+ +LR   VK 
Sbjct  62   KLMHQASLLGESIHDASHYGWEINENCSHSWEKMKDNVQNHIGSINFGYRVQLRDRKVK-  120

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y N++ T +D +T+K  D+RGKE+++TA+  +I++G RP     PGA E C+TSDD+F  
Sbjct  121  YLNAYGTLVDPHTIKAVDRRGKETLLTAKNFVISSGCRPRYPDIPGAKEHCVTSDDLFSL  180

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            +  PGKTLV+GASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA+R+GKYM+  G K
Sbjct  181  EKCPGKTLVIGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQDMAERVGKYMKDIGIK  240

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P   E       +     +   + + +     FDTVL+A+GR  C   + LDNA
Sbjct  241  FIRPAVPLSVEAITMNDGKKVLNVNYTMLDNGNKAQDKFDTVLLAIGRDPCTVNIGLDNA  300

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV    +     V+  E TN+ +IY IGD++    ELTPVAI +G++LA RL G +++  
Sbjct  301  GVVVEKNGYIKTVN--EQTNVPSIYGIGDILYDKPELTPVAIHAGRLLAKRLSGVSTQQC  358

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLIVYHSFFKPLLWALNKDRGDADCYMKV  422
            DY ++PTT+FTP+EY   G SEE A E+ GDD+ VYH+ F PL W +   R +  CY+K+
Sbjct  359  DYDSIPTTIFTPLEYSCCGLSEEVAIEKLGDDVEVYHAQFMPLEWTI-PHRDENSCYLKL  417

Query  423  LCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQI  482
            +C  +  ++V+GIHILGP++GE++QG A AMK G TKA+ DDTVGIHPT AE FTTL   
Sbjct  418  ICNKRDQERVIGIHILGPNSGEVMQGFATAMKCGATKAHFDDTVGIHPTNAEWFTTLRIT  477

Query  483  KEDG  486
            +  G
Sbjct  478  RRSG  481


>gb|AAN06824.1|  thioredoxin reductase [Sus scrofa]
Length=480

 GENE ID: 396681 TRXR1 | thioredoxin reductase [Sus scrofa]
(10 or fewer PubMed links)

 Score =  491 bits (1263),  Expect = 8e-137, Method: Compositional matrix adjust.
 Identities = 261/478 (54%), Positives = 330/478 (69%), Gaps = 12/478 (2%)

Query  6    SVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKK  65
             +YD+DL +IGGGSGGLAAAK AA    RV + DFV P+P GT WGLGGTCVNVGCIPKK
Sbjct  3    EMYDYDLIIIGGGSGGLAAAKEAARFNKRVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKK  62

Query  66   LLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXY  123
            L+H +A   +   DS   GW  E T  H+WE M + V  +I SLNWGY+  LR   V  Y
Sbjct  63   LMHQAALLGQALRDSRNYGWNVEETIKHDWERMTEAVQNHIGSLNWGYRVALREKKV-TY  121

Query  124  FNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRK  183
             N++  F+  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD+F   
Sbjct  122  ENAYGQFVGPHRIKATNNKGKEKIYSAEKFLIATGERPRYLGIPGDKEYCISSDDLFSLP  181

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG KF
Sbjct  182  YCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGVKF  241

Query  244  VHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLD  300
            + + +P K E+ E    G++RV AK+   T SD   E G ++TVL+A+GR  C   + L+
Sbjct  242  IRQFVPIKVEQIEAGMPGRLRVTAKA---TNSDETIE-GEYNTVLLAIGRDACTRNIGLE  297

Query  301  NAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASR  360
              GV  N   GKIPV   E TN+  +Y IGD++EG  ELTPVAIQ+G++LA RL+GG++ 
Sbjct  298  TVGVEINEKTGKIPVTDEEQTNVPYVYTIGDILEGKPELTPVAIQAGRLLAQRLYGGSTV  357

Query  361  LMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCY  419
              DY NVPTTVFTP+EYG+ G SEE A E++G++ I +YHS+F PL W +   R +  CY
Sbjct  358  KCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEIYHSYFWPLEWTI-PSRDNNKCY  416

Query  420  MKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
             K++C  K +++VVG HILGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  417  AKIVCNIKDNERVVGFHILGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVFT  474


>ref|XP_001696072.1|  NADPH-dependent thioredoxin reductase 1 [Chlamydomonas reinhardtii]
 gb|EDP01021.1|  NADPH-dependent thioredoxin reductase 1 [Chlamydomonas reinhardtii]
Length=505

 GENE ID: 5721705 NTR1 | NADPH-dependent thioredoxin reductase 1
[Chlamydomonas reinhardtii] (10 or fewer PubMed links)

 Score =  490 bits (1262),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 256/490 (52%), Positives = 328/490 (66%), Gaps = 19/490 (3%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            Y++DL VIGGGSGGLA AK AA LG +V L D+V PSP GT+WGLGGTCVNVGCIPKKL+
Sbjct  14   YEYDLVVIGGGSGGLACAKEAAKLGKKVCLLDYVVPSPAGTSWGLGGTCVNVGCIPKKLM  73

Query  68   HMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +    E   D+ G GW+L      NWE ++  V  +I SLNWGY+  LR  +VK Y N
Sbjct  74   HNAGLLGEGFSDARGYGWKLPEKIEMNWEDLVMGVQNHIGSLNWGYRVALREASVK-YLN  132

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            +  +F+D +T++  ++ G +  +TA  ++IA GGRP   G PG  E CITSDDIF R  P
Sbjct  133  AKGSFVDAHTVEAVERNGTKHTLTAERVVIAVGGRPKYLGVPGDKELCITSDDIFSRATP  192

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASYIALECAGF+   GY+  VM RSI LRGFDQ++A+ IGK ME  G + + 
Sbjct  193  PGKTLVVGASYIALECAGFLRALGYEVAVMARSIFLRGFDQEIAELIGKDMERRGVRMIK  252

Query  246  EMIPTKFEKTEDG-KVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
              +PT FE+  DG +++   K+    +  ++S    FDTVL+AVGR  C   L L+  GV
Sbjct  253  PAVPTAFER--DGEQIKCTFKNLDFGVEMSES----FDTVLLAVGRDACTFDLGLEKVGV  306

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
             Y+   GKIPV   E TN+ +IYAIGDV+E   ELTPVAI++G  LA RL+ GA+  MDY
Sbjct  307  TYDKSSGKIPVTA-EQTNVPSIYAIGDVLESRQELTPVAIKAGIRLARRLYAGATLQMDY  365

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKD-------RGDA  416
              VPTTVFTP+EYG VG SEE A  +YG D++ VY S+ KPL W +N +       R D 
Sbjct  366  DAVPTTVFTPLEYGCVGYSEEAATVKYGADNIEVYVSYLKPLEWTMNHEEHNGEPVRADN  425

Query  417  DCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETF  476
              ++K++     +++VVG H LGP+AGE+IQG+AVA+KA  TKA+ DD +GIHPT AE F
Sbjct  426  SVFVKLITNTADNERVVGAHYLGPNAGEIIQGVAVAVKANATKADFDDCIGIHPTVAEEF  485

Query  477  TTLTQIKEDG  486
            T L   K  G
Sbjct  486  TILEVTKRSG  495


>dbj|BAB28419.1|  unnamed protein product [Mus musculus]
 dbj|BAC37890.1|  unnamed protein product [Mus musculus]
 gb|AAH76605.1|  Thioredoxin reductase 3 [Mus musculus]
 gb|EDK99269.1|  thioredoxin reductase 3 [Mus musculus]
Length=613

 GENE ID: 232223 Txnrd3 | thioredoxin reductase 3 [Mus musculus]
(Over 10 PubMed links)

 Score =  490 bits (1261),  Expect = 1e-136, Method: Compositional matrix adjust.
 Identities = 258/488 (52%), Positives = 330/488 (67%), Gaps = 12/488 (2%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S +D+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGTTWGLGGTCVNVGCIPK
Sbjct  124  DSAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPK  183

Query  65   KLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A       D+   GWE      HNWEAM + + ++I SLNWGY+  LR   V  
Sbjct  184  KLMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGV-T  242

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NSF  F+D + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F  
Sbjct  243  YVNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSL  302

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PG TLVVGASY+ LECAGF+AG G D TVMVRS+LLRGFDQ+MA+++G Y+E  G K
Sbjct  303  PYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVK  362

Query  243  FVHEMIP---TKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSL  299
            F  +  P    + EK   GK++V AKS+       ++  G+++TVL+A+GR  C   + L
Sbjct  363  FQRKFTPILVQQLEKGLPGKLKVVAKST----EGPETVEGIYNTVLLAIGRDSCTRKIGL  418

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            +  GV  N   GKIPV+  E TN+ ++YAIGD+++G  ELTPVAIQ+GK+LA RLFG + 
Sbjct  419  EKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSL  478

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADC  418
               DY N+PTTVFTP+EYG  G SEE A E Y  ++L VYH+ F PL W +   R +  C
Sbjct  479  EKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTV-AGRDNNTC  537

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    +++VVG H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTT
Sbjct  538  YAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTT  597

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  598  LEITKSSG  605


>sp|Q99MD6.2|TRXR3_MOUSE  RecName: Full=Thioredoxin reductase 3; AltName: Full=Thioredoxin 
reductase TR2; AltName: Full=Thioredoxin and glutathione 
reductase
Length=697

 GENE ID: 232223 Txnrd3 | thioredoxin reductase 3 [Mus musculus]
(Over 10 PubMed links)

 Score =  490 bits (1261),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 258/488 (52%), Positives = 330/488 (67%), Gaps = 12/488 (2%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S +D+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGTTWGLGGTCVNVGCIPK
Sbjct  206  DSAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPK  265

Query  65   KLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A       D+   GWE      HNWEAM + + ++I SLNWGY+  LR   V  
Sbjct  266  KLMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGV-T  324

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NSF  F+D + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F  
Sbjct  325  YVNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSL  384

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PG TLVVGASY+ LECAGF+AG G D TVMVRS+LLRGFDQ+MA+++G Y+E  G K
Sbjct  385  PYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVK  444

Query  243  FVHEMIP---TKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSL  299
            F  +  P    + EK   GK++V AKS+       ++  G+++TVL+A+GR  C   + L
Sbjct  445  FQRKFTPILVQQLEKGLPGKLKVVAKST----EGPETVEGIYNTVLLAIGRDSCTRKIGL  500

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            +  GV  N   GKIPV+  E TN+ ++YAIGD+++G  ELTPVAIQ+GK+LA RLFG + 
Sbjct  501  EKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSL  560

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADC  418
               DY N+PTTVFTP+EYG  G SEE A E Y  ++L VYH+ F PL W +   R +  C
Sbjct  561  EKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTV-AGRDNNTC  619

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    +++VVG H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTT
Sbjct  620  YAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTT  679

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  680  LEITKSSG  687


>ref|NP_694802.2|  thioredoxin reductase 3 [Mus musculus]
 gb|AAK31172.1|AF349659_1  thioredoxin and glutathione reductase [Mus musculus]
Length=615

 GENE ID: 232223 Txnrd3 | thioredoxin reductase 3 [Mus musculus]
(Over 10 PubMed links)

 Score =  489 bits (1260),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 258/488 (52%), Positives = 330/488 (67%), Gaps = 12/488 (2%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            +S +D+DL +IGGGSGGL+ AK AA LG +V + DFV PSPQGTTWGLGGTCVNVGCIPK
Sbjct  124  DSAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPK  183

Query  65   KLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRSTNVKX  122
            KL+H +A       D+   GWE      HNWEAM + + ++I SLNWGY+  LR   V  
Sbjct  184  KLMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGV-T  242

Query  123  YFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRR  182
            Y NSF  F+D + +K T+K+G+E+  TA   +IATG RP   G  G  E CITSDD+F  
Sbjct  243  YVNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSL  302

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
               PG TLVVGASY+ LECAGF+AG G D TVMVRS+LLRGFDQ+MA+++G Y+E  G K
Sbjct  303  PYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVK  362

Query  243  FVHEMIP---TKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSL  299
            F  +  P    + EK   GK++V AKS+       ++  G+++TVL+A+GR  C   + L
Sbjct  363  FQRKFTPILVQQLEKGLPGKLKVVAKST----EGPETVEGIYNTVLLAIGRDSCTRKIGL  418

Query  300  DNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGAS  359
            +  GV  N   GKIPV+  E TN+ ++YAIGD+++G  ELTPVAIQ+GK+LA RLFG + 
Sbjct  419  EKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSL  478

Query  360  RLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-GDDLIVYHSFFKPLLWALNKDRGDADC  418
               DY N+PTTVFTP+EYG  G SEE A E Y  ++L VYH+ F PL W +   R +  C
Sbjct  479  EKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTV-AGRDNNTC  537

Query  419  YMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTT  478
            Y K++C    +++VVG H+LGP+AGE+ QG A AMK G TK  LDDT+GIHPTC E FTT
Sbjct  538  YAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTT  597

Query  479  LTQIKEDG  486
            L   K  G
Sbjct  598  LEITKSSG  605


>gb|EAW79356.1|  hCG40656, isoform CRA_b [Homo sapiens]
Length=459

 Score =  489 bits (1259),  Expect = 2e-136, Method: Compositional matrix adjust.
 Identities = 246/454 (54%), Positives = 307/454 (67%), Gaps = 12/454 (2%)

Query  39   DFVKPSPQGTTWGLGGTCVNVGCIPKKLLHMSAHTAETAGDSAGLGWELTAS--HNWEAM  96
            DFV PSPQGT+WGLGGTCVNVGCIPKKL+H +A   +   DS   GWE      HNWE M
Sbjct  4    DFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETM  63

Query  97   IQNVTTYISSLNWGYKSELRSTNVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIA  156
             + +  +ISSLNWGY+  LR   V  Y NS+  F++ + +K T+K+G+E+  TA   +IA
Sbjct  64   TKAIQNHISSLNWGYRLSLREKAV-AYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIA  122

Query  157  TGGRPNLGGYPGAGECCITSDDIFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMV  216
            TG RP   G  G  E CITSDD+F     PGKTLVVGASY+ALECAGF+AGFG D TVMV
Sbjct  123  TGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMV  182

Query  217  RSILLRGFDQDMAQRIGKYMELHGTKFVHEMIPT---KFEKTEDGKVRVYAKSSSDTMSD  273
            RSILLRGFDQ+MA+++G YME HG KF+ + IP    + EK   GK++V AKS+  T   
Sbjct  183  RSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGT---  239

Query  274  ADSEFGVFDTVLMAVGRTGCAGWLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVV  333
             ++  GV++TVL+A+GR  C   + L+  GV  N   GKIPV+  E TN+  +YA+GD++
Sbjct  240  -ETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDIL  298

Query  334  EGMLELTPVAIQSGKMLAARLFGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEY-G  392
            E   ELTPVAIQSGK+LA RLFG +    DY NVPTTVFTP+EYG  G SEE A E Y  
Sbjct  299  EDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKK  358

Query  393  DDLIVYHSFFKPLLWALNKDRGDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVA  452
            ++L +YH+ F PL W +   R +  CY K++C      +V+G HILGP+AGE+ QG A A
Sbjct  359  ENLEIYHTLFWPLEWTV-AGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAA  417

Query  453  MKAGCTKANLDDTVGIHPTCAETFTTLTQIKEDG  486
            MK G TK  LDDT+GIHPTC E FTTL   K  G
Sbjct  418  MKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSG  451


>emb|CAH92925.2|  thioredoxin reductase [Pongo abelii]
Length=499

 GENE ID: 100174180 TXNRD1 | thioredoxin reductase 1 [Pongo abelii]

 Score =  488 bits (1257),  Expect = 4e-136, Method: Compositional matrix adjust.
 Identities = 262/492 (53%), Positives = 335/492 (68%), Gaps = 12/492 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V + DFV P+P GT WGL GTCVNVG
Sbjct  4    PEDLPESYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLEGTCVNVG  63

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  64   CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  123

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  124  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  182

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTL+VGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  183  LFSLPYCPGKTLIVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  242

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K  + E    G++RV A+S   T S+   E G ++TVL+A+GR  C  
Sbjct  243  HGIKFIRQFVPIKVGQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVLLAIGRDACTR  298

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  299  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  358

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL   +   R 
Sbjct  359  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLERTI-PSRD  417

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  418  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  477

Query  475  TFTTLTQIKEDG  486
             FTTL+  K  G
Sbjct  478  VFTTLSVTKRSG  489


>dbj|BAC87474.1|  unnamed protein product [Homo sapiens]
Length=581

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  487 bits (1254),  Expect = 9e-136, Method: Compositional matrix adjust.
 Identities = 259/483 (53%), Positives = 332/483 (68%), Gaps = 12/483 (2%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P+     YD+DL +IGGGSGGLAAAK AA  G +V +  FV P+P GT WGLGGTCVNVG
Sbjct  103  PEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLVFVTPTPLGTRWGLGGTCVNVG  162

Query  61   CIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A   +   DS   GW  E T  H+W+ MI+ V  +I SLNWGY+  LR  
Sbjct  163  CIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREK  222

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDD  178
             V  Y N++  FI  + +K T+ +GKE I +A   LIATG RP   G PG  E CI+SDD
Sbjct  223  KV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDD  281

Query  179  IFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMEL  238
            +F     PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME 
Sbjct  282  LFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEE  341

Query  239  HGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAG  295
            HG KF+ + +P K E+ E    G++RV A+S   T S+   E G ++TV++A+GR  C  
Sbjct  342  HGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSEEIIE-GEYNTVMLAIGRDACTR  397

Query  296  WLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLF  355
             + L+  GV  N   GKIPV   E TN+  IYAIGD++E  +ELTPVAIQ+G++LA RL+
Sbjct  398  KIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLY  457

Query  356  GGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRG  414
             G++   DY NVPTTVFTP+EYG+ G SEE A E++G++ I VYHS+F PL W +   R 
Sbjct  458  AGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTI-PSRD  516

Query  415  DADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAE  474
            +  CY K++C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE
Sbjct  517  NNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE  576

Query  475  TFT  477
             F+
Sbjct  577  FFS  579


>dbj|BAH12374.1|  unnamed protein product [Homo sapiens]
Length=459

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  484 bits (1247),  Expect = 5e-135, Method: Compositional matrix adjust.
 Identities = 243/454 (53%), Positives = 311/454 (68%), Gaps = 12/454 (2%)

Query  39   DFVKPSPQGTTWGLGGTCVNVGCIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAM  96
            DFV P+P GT WGLGGTCVNVGCIPKKL+H +A   +   DS   GW  E T  H+W+ M
Sbjct  4    DFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRM  63

Query  97   IQNVTTYISSLNWGYKSELRSTNVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIA  156
            I+ V  +I SLNWGY+  LR   V  Y N++  FI  + +K T+ +GKE I +A   LIA
Sbjct  64   IEAVQNHIGSLNWGYRVALREKKV-VYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIA  122

Query  157  TGGRPNLGGYPGAGECCITSDDIFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMV  216
            TG RP   G PG  E CI+SDD+F     PGKTLVVGASY+ALECAGF+AG G D TVMV
Sbjct  123  TGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMV  182

Query  217  RSILLRGFDQDMAQRIGKYMELHGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSD  273
            RSILLRGFDQDMA +IG++ME HG KF+ + +P K E+ E    G++RV A+S   T S+
Sbjct  183  RSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSE  239

Query  274  ADSEFGVFDTVLMAVGRTGCAGWLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVV  333
               E G ++T ++A+GR  C   + L+  GV  N   GKIPV   E TN+  IYAIGD++
Sbjct  240  EIIE-GEYNTAMLAMGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDIL  298

Query  334  EGMLELTPVAIQSGKMLAARLFGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGD  393
            E  +ELTPVAIQ+G++LA RL+ G++   DY NVPTTVFTP+EYG+ G SEE A E++G+
Sbjct  299  EDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGE  358

Query  394  DLI-VYHSFFKPLLWALNKDRGDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVA  452
            + I VYHS+F PL W +   R +  CY K++C  K +++VVG H+LGP+AGE+ QG A A
Sbjct  359  ENIEVYHSYFWPLEWTI-PSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAA  417

Query  453  MKAGCTKANLDDTVGIHPTCAETFTTLTQIKEDG  486
            +K G TK  LD T+GIHP CAE FTTL+  K  G
Sbjct  418  LKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSG  451


>dbj|BAH11490.1|  unnamed protein product [Homo sapiens]
Length=459

 GENE ID: 7296 TXNRD1 | thioredoxin reductase 1 [Homo sapiens]
(Over 10 PubMed links)

 Score =  484 bits (1246),  Expect = 7e-135, Method: Compositional matrix adjust.
 Identities = 243/454 (53%), Positives = 311/454 (68%), Gaps = 12/454 (2%)

Query  39   DFVKPSPQGTTWGLGGTCVNVGCIPKKLLHMSAHTAETAGDSAGLGW--ELTASHNWEAM  96
            DFV P+P GT WGLGGTCVNVGCIPKKL+H +A   +   DS   GW  E T  H+W+ M
Sbjct  4    DFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRM  63

Query  97   IQNVTTYISSLNWGYKSELRSTNVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIA  156
            I+ V  +I SLNWGY+  LR   V  Y N++  FI  + +K T+ + KE I +A   LIA
Sbjct  64   IEAVQNHIGSLNWGYRVALREKKV-VYENAYGQFIGPHRIKATNNKDKEKIYSAERFLIA  122

Query  157  TGGRPNLGGYPGAGECCITSDDIFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMV  216
            TG RP   G PG  E CI+SDD+F     PGKTLVVGASY+ALECAGF+AG G D TVMV
Sbjct  123  TGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMV  182

Query  217  RSILLRGFDQDMAQRIGKYMELHGTKFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSD  273
            RSILLRGFDQDMA +IG++ME HG KF+ + +P K E+ E    G++RV A+S   T S+
Sbjct  183  RSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQS---TNSE  239

Query  274  ADSEFGVFDTVLMAVGRTGCAGWLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVV  333
               E G ++TV++A+GR  C   + L+  GV  N   GKIPV   E TN+  IYAIGD++
Sbjct  240  EIIE-GEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDIL  298

Query  334  EGMLELTPVAIQSGKMLAARLFGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGD  393
            E  +ELTPVAIQ+G++LA RL+ G++   DY NVPTTVFTP+EYG+ G SEE A E++G+
Sbjct  299  EDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGE  358

Query  394  DLI-VYHSFFKPLLWALNKDRGDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVA  452
            + I VYHS+F PL W +   R +  CY K++C  K +++VVG H+LGP+AGE+ QG A A
Sbjct  359  ENIEVYHSYFWPLEWTI-PSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAA  417

Query  453  MKAGCTKANLDDTVGIHPTCAETFTTLTQIKEDG  486
            +K G TK  LD T+GIHP CAE FTTL+  K  G
Sbjct  418  LKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSG  451


>gb|AAC35244.2|  thioredoxin reductase [Rattus norvegicus]
Length=497

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  484 bits (1245),  Expect = 9e-135, Method: Compositional matrix adjust.
 Identities = 267/489 (54%), Positives = 336/489 (68%), Gaps = 12/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT  GLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTNGGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A+K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFT  480

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  481  TLSVTKRSG  489


>ref|XP_001455671.1|  hypothetical protein [Paramecium tetraurelia strain d4-2]
 emb|CAK88274.1|  unnamed protein product [Paramecium tetraurelia]
Length=486

 GENE ID: 5041456 GSPATT00003243001 | hypothetical protein
[Paramecium tetraurelia strain d4-2]

 Score =  482 bits (1241),  Expect = 3e-134, Method: Compositional matrix adjust.
 Identities = 251/480 (52%), Positives = 321/480 (66%), Gaps = 14/480 (2%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DLFVIGGGSGGLA AK AA LGA+VALADFVKPSP GT WGLGGTCVNVGCIPKKL+H
Sbjct  6    QYDLFVIGGGSGGLACAKQAAKLGAKVALADFVKPSPLGTKWGLGGTCVNVGCIPKKLMH  65

Query  69   MSAHTAETAGDSAGLGW---ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
             +A   E   D    GW   ++ + HNWE M++NV  +I  LN+GYK++L   +VK Y+N
Sbjct  66   FAATLGELRHDQVEAGWVDTQVDSKHNWEKMVENVNNHIRKLNFGYKNQLMRGDVK-YYN  124

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNL-GGYPGAGECCITSDDIFRRKA  184
              A  ID NT+KLTD +G+   VTA+ ILIA GGRP+     P   +  ITSDD+F  + 
Sbjct  125  KLAELIDANTIKLTDNKGQIETVTAKNILIAVGGRPSYPENIPNIQKLVITSDDLFWLQE  184

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY+ALEC GF+ G G +  +MVRSILLRGFDQ++A++IG YME  G +F+
Sbjct  185  NPGKTLVVGASYVALECGGFLHGIGNEVAIMVRSILLRGFDQEIAEKIGLYMEEKGIRFI  244

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
               +P   E TED K +V    +     +      +FDTVL+A GR      L+L+  GV
Sbjct  245  RGCVPDMIEATEDNKRKVTWIINGQKYEE------IFDTVLVATGRISDTQKLNLEKVGV  298

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
            + N + GKI     + T++ NI+AIGD VEG  ELTP AI+ G++LA RLF  A+ LM Y
Sbjct  299  NMNKN-GKILCSADDKTSVPNIFAIGDCVEGRPELTPTAIKCGQLLANRLFNKATELMSY  357

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
              V TTVFTP+EYG +G SEE+A +++G+D I VYHS FKPL W   +      C+ K++
Sbjct  358  EFVATTVFTPLEYGCIGYSEEDAIKKFGEDKITVYHSIFKPLEWNYFEMHSGESCFAKLI  417

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
              N  +++V+G H LGP AGE+ QG AVAMK G TK   D TVGIHPTC+E    +T +K
Sbjct  418  VLND-NRRVIGFHYLGPHAGEVTQGYAVAMKMGVTKEQFDSTVGIHPTCSEELVQVTAVK  476


>gb|AAF03359.1|AF136399_1  thioredoxin reductase [Mus musculus]
Length=528

 GENE ID: 26462 Txnrd2 | thioredoxin reductase 2 [Mus musculus]
(Over 10 PubMed links)

 Score =  481 bits (1238),  Expect = 7e-134, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  43   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  102

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  103  QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  161

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  162  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  218

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  219  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  278

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  279  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  334

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  335  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  394

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  395  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  453

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  454  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  513

Query  482  IKEDG  486
             K  G
Sbjct  514  SKRSG  518


>ref|NP_038739.2|  thioredoxin reductase 2 precursor [Mus musculus]
 gb|AAL90457.1|  thioredoxin reductase [Mus musculus]
 gb|AAH52157.3|  Thioredoxin reductase 2 [Mus musculus]
Length=527

 GENE ID: 26462 Txnrd2 | thioredoxin reductase 2 [Mus musculus]
(Over 10 PubMed links)

 Score =  481 bits (1237),  Expect = 8e-134, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  42   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  101

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  102  QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  160

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  161  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  217

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  218  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  277

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  278  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  333

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  334  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  393

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  394  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  452

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  453  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  512

Query  482  IKEDG  486
             K  G
Sbjct  513  SKRSG  517


>sp|Q9JLT4.4|TRXR2_MOUSE  RecName: Full=Thioredoxin reductase 2, mitochondrial; AltName: 
Full=Thioredoxin reductase TR3; Flags: Precursor
 gb|AAD51323.1|AF171053_1  thioredoxin reductase TR3 [Mus musculus]
Length=524

 GENE ID: 26462 Txnrd2 | thioredoxin reductase 2 [Mus musculus]
(Over 10 PubMed links)

 Score =  481 bits (1237),  Expect = 8e-134, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  39   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  98

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  99   QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  157

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  158  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  214

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  215  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  274

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  275  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  330

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  331  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  390

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  391  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  449

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  450  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  509

Query  482  IKEDG  486
             K  G
Sbjct  510  SKRSG  514


>gb|EDK97524.1|  thioredoxin reductase 2, isoform CRA_a [Mus musculus]
Length=525

 GENE ID: 26462 Txnrd2 | thioredoxin reductase 2 [Mus musculus]
(Over 10 PubMed links)

 Score =  481 bits (1237),  Expect = 8e-134, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  42   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  101

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  102  QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  160

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  161  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  217

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  218  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  277

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  278  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  333

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  334  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  393

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  394  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  452

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  453  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  512

Query  482  IKEDG  486
             K  G
Sbjct  513  SKRSG  517


>pdb|1ZDL|A  Chain A, Crystal Structure Of Mouse Thioredoxin Reductase Type 
2
 pdb|1ZKQ|A  Chain A, Crystal Structure Of Mouse Thioredoxin Reductase Type 
2
Length=517

 Score =  481 bits (1237),  Expect = 9e-134, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  32   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  91

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  92   QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  150

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  151  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  207

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  208  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  267

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  268  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  323

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  324  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  383

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  384  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  442

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  443  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  502

Query  482  IKEDG  486
             K  G
Sbjct  503  SKRSG  507


>dbj|BAA86986.2|  thioredoxin reductase 2 [Mus musculus]
Length=520

 GENE ID: 26462 Txnrd2 | thioredoxin reductase 2 [Mus musculus]
(Over 10 PubMed links)

 Score =  480 bits (1236),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 330/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
             +DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  35   SFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  94

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+ M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  95   QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  153

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T++  DK GK ++++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  154  KASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPR---YPTQVKGALEYGITSDDIFWL  210

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++ME HGT+
Sbjct  211  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQ  270

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+  +K    +++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  271  FLKGCVPSHIKKLPTNQLQVTWEDHASGKEDT----GTFDTVLWAIGRVPETRTLNLEKA  326

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            G+  NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  327  GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  386

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+++KPL + +  DR  + CY+K
Sbjct  387  DYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTV-ADRDASQCYIK  445

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  446  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHI  505

Query  482  IKEDG  486
             K  G
Sbjct  506  SKRSG  510


>ref|NP_072106.1|  thioredoxin reductase 2 precursor [Rattus norvegicus]
 sp|Q9Z0J5.3|TRXR2_RAT  RecName: Full=Thioredoxin reductase 2, mitochondrial; AltName: 
Full=Thioredoxin reductase TR3; Flags: Precursor
 gb|AAD13801.1|  thioredoxin reductase [Rattus norvegicus]
 gb|AAH85734.1|  Thioredoxin reductase 2 [Rattus norvegicus]
Length=526

 GENE ID: 50551 Txnrd2 | thioredoxin reductase 2 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score =  480 bits (1236),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 248/485 (51%), Positives = 333/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
            ++DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  41   NFDLLVIGGGSGGLACAKEAAQLGRKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  100

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+AM + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  101  QAALLGGMIRDAQHYGWEVAQPVQHNWKAMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  159

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F++ +T+   DK GK + ++A++I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  160  KASFVNEHTVHGVDKAGKVTQLSAKHIVIATGGRPK---YPTQVKGALEHGITSDDIFWL  216

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RS+ LRGFDQ MA  + ++ME HGT+
Sbjct  217  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSVPLRGFDQQMASLVTEHMESHGTR  276

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+   K    +++V    + + ++    + G FDTVL A+GR      L+L+ A
Sbjct  277  FLKGCVPSLIRKLPTNQLQV----TWEDLASGKEDVGTFDTVLWAIGRVPETRNLNLEKA  332

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV+ NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  333  GVNTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  392

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            +Y NVPTTVFTP+EYG VG SEE A   +G + I VYH+++KPL + +  DR  + CY+K
Sbjct  393  NYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTV-ADRDASQCYIK  451

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ ++ G + A +  TVGIHPTC+E    L  
Sbjct  452  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVVKLHI  511

Query  482  IKEDG  486
             K  G
Sbjct  512  SKRSG  516


>gb|EDL77943.1|  thioredoxin reductase 2, isoform CRA_a [Rattus norvegicus]
Length=524

 GENE ID: 50551 Txnrd2 | thioredoxin reductase 2 [Rattus norvegicus]
(10 or fewer PubMed links)

 Score =  480 bits (1236),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 248/485 (51%), Positives = 333/485 (68%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
            ++DL VIGGGSGGLA AK AA LG +VA+AD+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  41   NFDLLVIGGGSGGLACAKEAAQLGRKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  100

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     HNW+AM + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  101  QAALLGGMIRDAQHYGWEVAQPVQHNWKAMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  159

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F++ +T+   DK GK + ++A++I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  160  KASFVNEHTVHGVDKAGKVTQLSAKHIVIATGGRPK---YPTQVKGALEHGITSDDIFWL  216

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RS+ LRGFDQ MA  + ++ME HGT+
Sbjct  217  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSVPLRGFDQQMASLVTEHMESHGTR  276

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+   +P+   K    +++V    + + ++    + G FDTVL A+GR      L+L+ A
Sbjct  277  FLKGCVPSLIRKLPTNQLQV----TWEDLASGKEDVGTFDTVLWAIGRVPETRNLNLEKA  332

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV+ NP   KI VD  E T++ +IYAIGDV EG  ELTP AI++GK+LA RLFG +S LM
Sbjct  333  GVNTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLM  392

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            +Y NVPTTVFTP+EYG VG SEE A   +G + I VYH+++KPL + +  DR  + CY+K
Sbjct  393  NYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHIEVYHAYYKPLEFTV-ADRDASQCYIK  451

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ ++ G + A +  TVGIHPTC+E    L  
Sbjct  452  MVCMREPPQLVLGLHFLGPNAGEVTQGFALGIQCGASYAQVMQTVGIHPTCSEEVVKLHI  511

Query  482  IKEDG  486
             K  G
Sbjct  512  SKRSG  516


>ref|XP_001425944.1|  hypothetical protein [Paramecium tetraurelia strain d4-2]
 emb|CAK58546.1|  unnamed protein product [Paramecium tetraurelia]
Length=486

 GENE ID: 5011728 GSPATT00004919001 | hypothetical protein
[Paramecium tetraurelia strain d4-2]

 Score =  479 bits (1234),  Expect = 2e-133, Method: Compositional matrix adjust.
 Identities = 250/480 (52%), Positives = 321/480 (66%), Gaps = 14/480 (2%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
            ++DLFVIGGGSGGLA AK AA LGA+VALADFVKPSP GT WGLGGTCVNVGCIPKKL+H
Sbjct  6    EFDLFVIGGGSGGLACAKQAAKLGAKVALADFVKPSPLGTKWGLGGTCVNVGCIPKKLMH  65

Query  69   MSAHTAETAGDSAGLGW---ELTASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
             ++   E   D    GW   ++ + HNWE M++NV  +I  LN+GYK++L   +VK Y+N
Sbjct  66   FASTLGELRHDQVEAGWIDTQVDSKHNWEKMVENVNNHIRKLNFGYKNQLMRGDVK-YYN  124

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNL-GGYPGAGECCITSDDIFRRKA  184
              A  ID NT+KLTD +GK   V A+ I+IA GGRP+     P   +  ITSDD+F  + 
Sbjct  125  KLAELIDANTIKLTDNKGKIETVRAKTIVIAVGGRPSYPENIPNIQKLVITSDDLFWLQE  184

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLVVGASY+ALEC GF+ G G +  +MVRSILLRGFDQ++A++IG YME  G +F+
Sbjct  185  NPGKTLVVGASYVALECGGFLHGIGNEVAIMVRSILLRGFDQEIAEKIGLYMEEKGIRFI  244

Query  245  HEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
               +P   E TED K +V    +     +      +FDTVL+A GR      L+L+  GV
Sbjct  245  RGCVPDMIEATEDNKRKVTWILNGQKYEE------IFDTVLVATGRISDTQKLNLEKVGV  298

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMDY  364
            + N + GKI     + T++ NI+AIGD VEG  ELTP AI+ G++LA RLF  A+ LM Y
Sbjct  299  NLNKN-GKILCSADDKTSVPNIFAIGDCVEGRPELTPTAIKCGQLLANRLFNKANELMSY  357

Query  365  HNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKVL  423
              V TTVFTP+EYG +G SEE+A +++G+D I VYHS FKPL W   +      C+ K++
Sbjct  358  DYVATTVFTPLEYGCIGYSEEDAIKKFGEDKITVYHSIFKPLEWNYFEMHSGESCFAKLI  417

Query  424  CENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIK  483
              N  +++V+G H LGP AGE+ QG AVAMK G TK   D TVGIHPTC+E    +T IK
Sbjct  418  VLN-NNRRVIGFHYLGPHAGEVTQGYAVAMKMGVTKEQFDSTVGIHPTCSEELVQVTAIK  476


>sp|O89049.4|TRXR1_RAT  RecName: Full=Thioredoxin reductase 1, cytoplasmic; Short=TR; 
AltName: Full=Thioredoxin reductase TR1; AltName: Full=NADPH-dependent 
thioredoxin reductase
Length=498

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  478 bits (1231),  Expect = 5e-133, Method: Compositional matrix adjust.
 Identities = 267/489 (54%), Positives = 335/489 (68%), Gaps = 13/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT  GLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTNGGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ QG A A K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAA-KCGLTKQQLDSTIGIHPVCAEIFT  479

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  480  TLSVTKRSG  488


>ref|NP_001116163.1|  thioredoxin reductase 2 [Gallus gallus]
Length=518

 GENE ID: 416782 TXNRD2 | thioredoxin reductase 2 [Gallus gallus]
(10 or fewer PubMed links)

 Score =  476 bits (1224),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 252/489 (51%), Positives = 330/489 (67%), Gaps = 20/489 (4%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
            ++DL VIGGGSGGLA AK AA  G  VA+ D+V+PSP+GT WGLGGTCVNVGCIPKKL+H
Sbjct  29   EYDLLVIGGGSGGLACAKEAAQFGKNVAVLDYVEPSPRGTKWGLGGTCVNVGCIPKKLMH  88

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GW +     HNW  M Q V  Y+ SLNWG++ +L+   VK YFN 
Sbjct  89   QAALLGGALKDAQHYGWSVAHPVHHNWSVMAQAVQNYVKSLNWGHRVQLQDKKVK-YFNM  147

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
              +F D +T+    K GKE+ +TA  I+IATGGRP    YP    GA E  ITSDD+F  
Sbjct  148  KGSFSDSHTVCGIAKGGKETTLTAEKIVIATGGRPK---YPTHITGALEYGITSDDLFWL  204

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVR----SILLRGFDQDMAQRIGKYMEL  238
            K  PGKTLVVGASY++LECAGF+ G G DTTV++R    SI LRGFDQ MA  + ++ME 
Sbjct  205  KDSPGKTLVVGASYVSLECAGFLTGIGLDTTVIMRIIMRSIPLRGFDQQMASLVTEHMES  264

Query  239  HGTKFVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            +GTKF+ + +P K EK E  +++V  K++     + DS    FDTV+ AVGR      L+
Sbjct  265  YGTKFLKKCVPAKVEKLESSRLQVTWKNTELGTEETDS----FDTVMWAVGRVPDIKTLN  320

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            LD+ GV  N + GKI VD  E T++ +IYAIGD+ EG  ELTP AI +GK+LA RLFG +
Sbjct  321  LDSVGVKTNSETGKIIVDASEATSVPHIYAIGDITEGRPELTPTAIAAGKLLARRLFGHS  380

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDLIVYHSFFKPLLWALNKDRGDAD  417
            S LMDY NVPTTVFTP+EYG VG SEE A + YG D++ V+H+++KPL + +  +R  A 
Sbjct  381  SELMDYDNVPTTVFTPLEYGCVGLSEEKAVQCYGSDNVEVFHAYYKPLEFTV-AERDAAQ  439

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY+K++C  + +++++G+H +GP+AGE+IQG A+ +K G T   L  T+GIHPTCAE  T
Sbjct  440  CYIKMVCLREREQRILGLHFIGPNAGEVIQGFALGIKCGATYPQLMKTIGIHPTCAEEIT  499

Query  478  TLTQIKEDG  486
             L   K  G
Sbjct  500  KLHITKRSG  508


>gb|AAF32362.1|AF220760_1  thioredoxin reductase 1 [Rattus norvegicus]
Length=498

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  476 bits (1224),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 265/489 (54%), Positives = 334/489 (68%), Gaps = 13/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT  GLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTNGGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ Q L   +K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQALQ-PLKCGLTKQQLDSTIGIHPVCAEIFT  479

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  480  TLSVTKRSG  488


>gb|AAD43039.1|AF108213_1  NADPH-dependent thioredoxin reductase [Rattus norvegicus]
Length=496

 GENE ID: 58819 Txnrd1 | thioredoxin reductase 1 [Rattus norvegicus]
(Over 10 PubMed links)

 Score =  476 bits (1224),  Expect = 3e-132, Method: Compositional matrix adjust.
 Identities = 265/489 (54%), Positives = 334/489 (68%), Gaps = 13/489 (2%)

Query  4    AESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIP  63
            A   YD+DL +IGGGSGGLAAAK AA    +V + DFV P+P GT  GLGGTCVNVGCIP
Sbjct  7    APKSYDFDLIIIGGGSGGLAAAKEAAKFDKKVMVLDFVTPTPLGTNGGLGGTCVNVGCIP  66

Query  64   KKLLHMSAHTAETAGDSAGLGWEL--TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KKL+H +A   +   DS   GW+L  T  H+WE M ++V  +I SLNWGY+  LR   V 
Sbjct  67   KKLMHQAALLGQALKDSRNYGWKLEDTVKHDWEKMTESVQNHIGSLNWGYRVALREKKV-  125

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N++  FI  + +  T+ +GKE + +A   LIATG RP   G PG  E CI+SDD+F 
Sbjct  126  VYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEYCISSDDLFS  185

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
                PGKTLVVGASY+ALECAGF+AG G D TVMVRSILLRGFDQDMA +IG++ME HG 
Sbjct  186  LPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI  245

Query  242  KFVHEMIPTKFEKTE---DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLS  298
            KF+ + +PTK E+ E    G+++V AKS++   +  D     F+TVL+AVGR  C   + 
Sbjct  246  KFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDE----FNTVLLAVGRDSCTRTIG  301

Query  299  LDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGA  358
            L+  GV  N   GKIPV   E TN+  IYAIGD++EG LELTPVAIQ+G++LA RL+GG+
Sbjct  302  LETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGS  361

Query  359  SRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDAD  417
            +   DY NVPTTVFTP+EYG  G SEE A E++G++ I VYHSFF PL W +   R +  
Sbjct  362  TVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTV-PSRDNNK  420

Query  418  CYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFT  477
            CY KV+C  K +++VVG H+LGP+AGE+ Q L   +K G TK  LD T+GIHP CAE FT
Sbjct  421  CYAKVICNLKDNERVVGFHVLGPNAGEVTQALQ-PLKCGLTKQQLDSTIGIHPVCAEIFT  479

Query  478  TLTQIKEDG  486
            TL+  K  G
Sbjct  480  TLSVTKRSG  488


>gb|AAN32903.1|  thioredoxin reductase TR1 [Chlamydomonas reinhardtii]
Length=533

 Score =  475 bits (1222),  Expect = 5e-132, Method: Compositional matrix adjust.
 Identities = 256/518 (49%), Positives = 328/518 (63%), Gaps = 47/518 (9%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            Y++DL VIGGGSGGLA AK AA LG +V L D+V PSP GT+WGLGGTCVNVGCIPKKL+
Sbjct  14   YEYDLVVIGGGSGGLACAKEAAKLGKKVCLLDYVVPSPAGTSWGLGGTCVNVGCIPKKLM  73

Query  68   HMSAHTAETAGDSAGLGWELTA--SHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFN  125
            H +    E   D+ G GW+L      NWE ++  V  +I SLNWGY+  LR  +VK Y N
Sbjct  74   HNAGLLGEGFSDARGYGWKLPEKIEMNWEDLVMGVQNHIGSLNWGYRVALREASVK-YLN  132

Query  126  SFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKAP  185
            +  +F+D +T++  ++ G +  +TA  ++IA GGRP   G PG  E CITSDDIF R  P
Sbjct  133  AKGSFVDAHTVEAVERNGTKHTLTAERVVIAVGGRPKYLGVPGDKELCITSDDIFSRATP  192

Query  186  PGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFVH  245
            PGKTLVVGASYIALECAGF+   GY+  VM RSI LRGFDQ++A+ IGK ME  G + + 
Sbjct  193  PGKTLVVGASYIALECAGFLRALGYEVAVMARSIFLRGFDQEIAELIGKDMERRGVRMIK  252

Query  246  EMIPTKFEKTEDG-KVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAGV  304
              +PT FE+  DG +++   K+    +  ++S    FDTVL+AVGR  C   L L+  GV
Sbjct  253  PAVPTAFER--DGEQIKCTFKNLDFGVEMSES----FDTVLLAVGRDACTFDLGLEKVGV  306

Query  305  HYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGM----------------------------  336
             Y+   GKIPV   E TN+ +IYAIGDV+E                              
Sbjct  307  TYDKSSGKIPVTA-EQTNVPSIYAIGDVLESRQVPGQGGRKLMGLTCSLAQTLSPPDPLA  365

Query  337  LELTPVAIQSGKMLAARLFGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYG-DDL  395
             ELTPVAI++G  LA RL+ GA+  MDY  VPTTVFTP+EYG VG SEE A  +YG D++
Sbjct  366  QELTPVAIKAGIRLARRLYAGATLQMDYDAVPTTVFTPLEYGCVGYSEEAATVKYGADNI  425

Query  396  IVYHSFFKPLLWALNKD-------RGDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQG  448
             VY S+ KPL W +N +       R D   ++K++     +++VVG H LGP+AGE+IQG
Sbjct  426  EVYVSYLKPLEWTMNHEEHNGEPVRADNSVFVKLITNTADNERVVGAHYLGPNAGEIIQG  485

Query  449  LAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQIKEDG  486
            +AVA+KA  TKA+ DD +GIHPT AE FT L   K  G
Sbjct  486  VAVAVKANATKADFDDCIGIHPTVAEEFTILEVTKRSG  523


>emb|CAM96615.1|  thioredoxin-glutathione reductase [Fasciola hepatica]
Length=598

 Score =  474 bits (1219),  Expect = 1e-131, Method: Compositional matrix adjust.
 Identities = 254/494 (51%), Positives = 330/494 (66%), Gaps = 21/494 (4%)

Query  5    ESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPK  64
            ++ YD+DL VIGGGSGGLAA+K AA  GA+ A+ DFV P+PQ TT GLGGTCVNVGCIPK
Sbjct  104  KNTYDYDLVVIGGGSGGLAASKEAARFGAKTAVFDFVVPTPQDTTRGLGGTCVNVGCIPK  163

Query  65   KLLHMSAHTAETAGDSAGLGWEL---TASHNWEAMIQNVTTYISSLNWGYKSELRSTNVK  121
            KL+H +A   E   DS   GW+       H+W  +++N+  +I SLNWGY+++LRS NV+
Sbjct  164  KLMHQAALLREGMPDSVHFGWKWDPEKIEHDWAQIVENIGNHIHSLNWGYRTQLRSINVE  223

Query  122  XYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFR  181
             Y N+FA  +D +T+K T K  +   VTA+ I++ATG RP   G PG  E  ITSDD+F 
Sbjct  224  -YVNAFAEVVDPHTIKYTKKNKETGTVTAKVIILATGERPRYPGIPGDKEYAITSDDLFW  282

Query  182  RKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGT  241
               PPGKTLVVGASY+ALECAGF+  FG+DTTVMVRSI LRGFDQ MA  IG+YM+ HGT
Sbjct  283  LPYPPGKTLVVGASYVALECAGFLTRFGFDTTVMVRSIFLRGFDQQMADMIGEYMKEHGT  342

Query  242  KFVHEMIPTKFEKTE--------DGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGC  293
            KFV   +PT  E+ E         G  RV  K       + +   G F+T++MA+GR   
Sbjct  343  KFVRSCVPTAIEEIEARDKENQKPGLYRVKGK-----YENGEEFVGEFNTIVMAIGRDPT  397

Query  294  AGWLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAAR  353
                ++++ G+  +  K  I  D  E +++D+IYAIGD+V G  +LTPVAI +G+ LA R
Sbjct  398  WDRKAMESVGLKLDKAKRVICADN-EQSSVDSIYAIGDIVSGKPQLTPVAIHAGRYLARR  456

Query  354  LFGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKD  412
            L+ G   L DY NVPTT+FTPIEYG+ G SEE+A  +YG + I VYHS F PL W +   
Sbjct  457  LYAGDIELTDYVNVPTTIFTPIEYGACGLSEEDAITKYGKENIEVYHSHFIPLEWTVPHR  516

Query  413  RGDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTC  472
              D   Y K++C     ++V+G+H+LGP+AGEM QG +VAMKAG TKA+ D T+GIHPTC
Sbjct  517  PEDG--YAKIICLKSDSERVIGLHVLGPNAGEMTQGFSVAMKAGATKADFDRTIGIHPTC  574

Query  473  AETFTTLTQIKEDG  486
             E FTT+   K+ G
Sbjct  575  FEGFTTMHVTKDSG  588


>ref|XP_850181.1|  PREDICTED: similar to thioredoxin reductase 2 isoform 1 precursor 
[Canis familiaris]
Length=509

 GENE ID: 608155 TXNRD2 | thioredoxin reductase 2 [Canis lupus familiaris]

 Score =  471 bits (1213),  Expect = 5e-131, Method: Compositional matrix adjust.
 Identities = 244/493 (49%), Positives = 331/493 (67%), Gaps = 16/493 (3%)

Query  1    PDPAESVYDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVG  60
            P  A    ++DL VIGGGSGGLA AK AA LG +VA+ D+V+PSP+GT WGLGGTCVNVG
Sbjct  18   PLSAAGQQNYDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVEPSPRGTKWGLGGTCVNVG  77

Query  61   CIPKKLLHMSAHTAETAGDSAGLGWELTAS--HNWEAMIQNVTTYISSLNWGYKSELRST  118
            CIPKKL+H +A       D+   GW++     H+W  M + V  ++ SLNWG++ +L+  
Sbjct  78   CIPKKLMHQAALLGSMIRDAPHYGWDVAQPVLHDWRTMAEAVQNHVKSLNWGHRVQLQDR  137

Query  119  NVKXYFNSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCI  174
             V  YFN  A+F++ +T+    K GKE++++A +I+IATGGRP    YP    GA E  I
Sbjct  138  KV-TYFNVKASFVNEHTVCGVAKGGKETLLSAEHIVIATGGRPR---YPTHIEGALEYGI  193

Query  175  TSDDIFRRKAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGK  234
            TSDDIF  K  PGKTLVVGASY+ALECAGF+ G G DTT+M+RSI LRGFDQ M+  + +
Sbjct  194  TSDDIFWLKESPGKTLVVGASYVALECAGFLTGLGLDTTIMIRSIPLRGFDQQMSSLVTE  253

Query  235  YMELHGTKFVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCA  294
            YM   GT+F+    P++  +  DG+++V    + + ++    + G FDTVL A+GR    
Sbjct  254  YMASQGTRFLRGCTPSRVRRLPDGQLQV----TWENLTSGKEDVGTFDTVLWAIGRIPET  309

Query  295  GWLSLDNAGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARL  354
              L+L+ AGV+ NP+  KI V+  E T+I +IYAIGDV EG  ELTP AI +G++LA RL
Sbjct  310  KSLNLEKAGVNTNPNSQKILVNAQEATSIPHIYAIGDVAEGRPELTPTAIMAGRLLAQRL  369

Query  355  FGGASRLMDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDR  413
             G AS +MDY NVPTTVFTP+EYG VG SEE A   +G++ + VYH+++KPL + +  +R
Sbjct  370  CGQASDVMDYDNVPTTVFTPLEYGCVGLSEEEAVTRHGEEHVEVYHAYYKPLEFTV-AER  428

Query  414  GDADCYMKVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCA  473
              + CY+K++C  K  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTCA
Sbjct  429  DASQCYVKMVCLRKPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCA  488

Query  474  ETFTTLTQIKEDG  486
            E    L   K  G
Sbjct  489  EEVAKLRITKRSG  501


>ref|XP_001105541.1|  PREDICTED: similar to thioredoxin reductase 2 precursor [Macaca 
mulatta]
Length=521

 GENE ID: 712475 LOC712475 | similar to thioredoxin reductase 2 precursor
[Macaca mulatta]

 Score =  471 bits (1211),  Expect = 8e-131, Method: Compositional matrix adjust.
 Identities = 249/485 (51%), Positives = 325/485 (67%), Gaps = 16/485 (3%)

Query  9    DWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLH  68
            D+DL VIGGGSGGLA AK AA LG +VA+ D+V+PSPQGT WGLGGTCVNVGCIPKKL+H
Sbjct  38   DYDLLVIGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMH  97

Query  69   MSAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNS  126
             +A       D+   GWE+     H+W  M + V  ++ SLNWG++ +L+   VK YFN 
Sbjct  98   QAALLGGLIQDAPHYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNI  156

Query  127  FATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRR  182
             A+F+D +T+    K GKE +++A +I+IATGGRP    YP    GA E  ITSDDIF  
Sbjct  157  KASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPR---YPTHIEGALEYGITSDDIFWL  213

Query  183  KAPPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTK  242
            K  PGKTLVVGASY+ALECAGF+ G G DTTVM+RSI LRGFDQ M+  + ++M  HGT+
Sbjct  214  KESPGKTLVVGASYVALECAGFLTGIGLDTTVMIRSIPLRGFDQQMSSMVIEHMASHGTQ  273

Query  243  FVHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNA  302
            F+    P++  +  DG ++V  +  +    D     G FDTVL A+GR      L+L+ A
Sbjct  274  FLRGCAPSRVRRLPDGHLQVTWEDCTTGKEDT----GTFDTVLWAIGRVPDTRSLNLEKA  329

Query  303  GVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLM  362
            GV  +PD  KI VD  E T++ +IYAIGDVVEG  ELTP AI +G++L  RLFGG+S LM
Sbjct  330  GVDTSPDTQKILVDSREGTSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLM  389

Query  363  DYHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMK  421
            DY NVPTTVFTP+EYG VG SEE A   +G + + VYH+ +KPL + +   R  + CY+K
Sbjct  390  DYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTV-AGRDASQCYVK  448

Query  422  VLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQ  481
            ++C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  TVGIHPTC+E    L  
Sbjct  449  MVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRI  508

Query  482  IKEDG  486
             K  G
Sbjct  509  SKRSG  513


>ref|XP_001488273.1|  PREDICTED: similar to TXNRD2 protein [Equus caballus]
Length=489

 GENE ID: 100051917 LOC100051917 | similar to TXNRD2 protein [Equus caballus]

 Score =  468 bits (1205),  Expect = 4e-130, Method: Compositional matrix adjust.
 Identities = 243/484 (50%), Positives = 328/484 (67%), Gaps = 16/484 (3%)

Query  10   WDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLLHM  69
            +DL VIGGGSGGLA AK AA LG +VA+ D+V+PSP+GT WGLGGTCVNVGCIPKKL+H 
Sbjct  7    YDLLVIGGGSGGLACAKEAAQLGKKVAVVDYVEPSPRGTRWGLGGTCVNVGCIPKKLMHQ  66

Query  70   SAHTAETAGDSAGLGWELT--ASHNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYFNSF  127
            +A       D+   GWE+     H+W  M + V  ++ SLNWG++ +L+   VK YFN  
Sbjct  67   AALLGGMIRDAPHYGWEVPPLVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVK-YFNIK  125

Query  128  ATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYP----GAGECCITSDDIFRRK  183
            A+F++ + +    K GKE++++A +I+IATGGRP    YP    GA E  ITSDDIF  K
Sbjct  126  ASFVNEHMVCGVTKDGKETLLSAEHIVIATGGRPR---YPTHIEGALEYGITSDDIFWLK  182

Query  184  APPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKF  243
              PGKTLVVGASY+ALECAGF+ G G D TVMVRSI LRGFDQ M+  + +YM  HGT+F
Sbjct  183  ESPGKTLVVGASYVALECAGFLTGLGLDATVMVRSIPLRGFDQQMSSLVTEYMASHGTRF  242

Query  244  VHEMIPTKFEKTEDGKVRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDNAG  303
            +    P++  +  DG+++V    + + ++    + G FDTVL A+GR      L L+NAG
Sbjct  243  LRGCTPSRVGRLPDGQLQV----TWEDLASGKKDVGTFDTVLWAIGRVPETRSLHLENAG  298

Query  304  VHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRLMD  363
            V+ +P+  KI VD  E T++ +IYAIGDV EG  ELTP A+ +GK+LA RL G +S LMD
Sbjct  299  VNTHPNSQKILVDAGEATSVPHIYAIGDVAEGRPELTPPAVMAGKLLARRLCGQSSDLMD  358

Query  364  YHNVPTTVFTPIEYGSVGSSEENAKEEYGDDLI-VYHSFFKPLLWALNKDRGDADCYMKV  422
            Y NVPTTVFTP+EYG VG SEE A   +G++ + VYH+++KPL + +  +R  + CY+K+
Sbjct  359  YDNVPTTVFTPLEYGCVGLSEEKAVARHGEEHVEVYHAYYKPLEFTV-AERDASQCYIKM  417

Query  423  LCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLTQI  482
            +C  +  + V+G+H LGP+AGE+ QG A+ +K G + A +  T+GIHPTCAE    L   
Sbjct  418  VCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTLGIHPTCAEEVAKLRIT  477

Query  483  KEDG  486
            K  G
Sbjct  478  KRSG  481


>ref|XP_002132000.1|  PREDICTED: similar to thioredoxin reductase 3 [Ciona intestinalis]
Length=621

 GENE ID: 100178436 LOC100178436 | similar to thioredoxin reductase 3
[Ciona intestinalis]

 Score =  466 bits (1200),  Expect = 2e-129, Method: Compositional matrix adjust.
 Identities = 239/486 (49%), Positives = 326/486 (67%), Gaps = 14/486 (2%)

Query  8    YDWDLFVIGGGSGGLAAAKTAAALGARVALADFVKPSPQGTTWGLGGTCVNVGCIPKKLL  67
            Y++DL VIGGGSGGLAA+K A+ LG +VA+ DFV+P+P+G +WGLGGTCVNVGCIPKKL+
Sbjct  135  YEYDLIVIGGGSGGLAASKRASELGKKVAVCDFVQPTPKGVSWGLGGTCVNVGCIPKKLM  194

Query  68   HMSAHTAETAGDSAGLGWELTAS---HNWEAMIQNVTTYISSLNWGYKSELRSTNVKXYF  124
            H ++   ++  D+   GW+LT+    + WE M++ V  YI SLNWGY+ +LR   V  Y 
Sbjct  195  HQASMLGKSIEDAKSFGWQLTSEPVKNKWEGMVEAVQNYIGSLNWGYRVQLREKKVN-YV  253

Query  125  NSFATFIDRNTLKLTDKRGKESIVTARYILIATGGRPNLGGYPGAGECCITSDDIFRRKA  184
            N++A F D++T+   ++RGKE+ +TA   ++A G RP     PGA E CITSDD+F    
Sbjct  254  NAYAKFEDQHTITTVNRRGKETKMTADKFIVAVGERPRYPDIPGAKEHCITSDDLFSLPY  313

Query  185  PPGKTLVVGASYIALECAGFIAGFGYDTTVMVRSILLRGFDQDMAQRIGKYMELHGTKFV  244
             PGKTLV+GASY+ALECAGF+ G G D TVMVRSI LRGFDQ MA +   YME  G +F+
Sbjct  314  CPGKTLVIGASYVALECAGFLKGIGLDVTVMVRSIFLRGFDQQMADKAAGYMEKEGVQFL  373

Query  245  HEMIPTKFEKTEDGK---VRVYAKSSSDTMSDADSEFGVFDTVLMAVGRTGCAGWLSLDN  301
               +P K E+ E G+   +RV  K +     + +   G ++TV++A+GR      + LD 
Sbjct  374  RRCVPVKIEQVEAGEPGLLRVTGKMT----ENGEEVTGDYNTVILAIGRDSVTKTIGLDK  429

Query  302  AGVHYNPDKGKIPVDKFEMTNIDNIYAIGDVVEGMLELTPVAIQSGKMLAARLFGGASRL  361
              V  + + GK+PV+ ++ TN++NI+ IGD  EG  ELTPVAI +G++L+ RL+GG++  
Sbjct  430  INVQVSKN-GKVPVNDYDQTNVENIFCIGDNGEGKPELTPVAIHAGRLLSERLYGGSTLK  488

Query  362  MDYHNVPTTVFTPIEYGSVGSSEENAKEEYGDD-LIVYHSFFKPLLWALNKDRGDADCYM  420
             DY  VPTTVFTP+EY   G SEE A  +YG+D L VYH+   PL W++     +  CY+
Sbjct  489  CDYEGVPTTVFTPLEYSCCGLSEEAAIAKYGEDNLEVYHTNVWPLEWSV-PGHDNNTCYV  547

Query  421  KVLCENKGDKKVVGIHILGPDAGEMIQGLAVAMKAGCTKANLDDTVGIHPTCAETFTTLT  480
            K +      ++V+G+H LGP+AGE++QG A AMK G TKA LD T+GIHPT AE FTTL 
Sbjct  548  KAITNKLDSERVIGLHYLGPNAGEVMQGFAAAMKCGITKAQLDQTIGIHPTTAELFTTLN  607

Query  481  QIKEDG  486
              K  G
Sbjct  608  VTKRSG  613
Select All Get selected sequences
gi|126302086|gb|AAXJ01000419.1|:subseq(0,7131).pep

Distribution of 100 Blast Hits on the Query Sequence [?]
