TBLASTN 2.2.17 [Aug-26-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= gi|8923460|ref|NP_060316.1| tRNA selenocysteine associated
protein 1 [Homo sapiens]
         (287 letters)

Database: genome.fa 
           35 sequences; 31,379,198 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75...    77   1e-14
gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75...    55   4e-08
gi|154335720|ref|NC_009310.1| Leishmania braziliensis MHOM/BR/75...    40   0.002
gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75...    39   0.005
gi|154341365|ref|NC_009321.1| Leishmania braziliensis MHOM/BR/75...    35   0.052
gi|154335056|ref|NC_009308.1| Leishmania braziliensis MHOM/BR/75...    33   0.18 
gi|154343652|ref|NC_009324.1| Leishmania braziliensis MHOM/BR/75...    31   1.1  
gi|154333023|ref|NC_009301.1| Leishmania braziliensis MHOM/BR/75...    31   1.2  
gi|154333356|ref|NC_009302.1| Leishmania braziliensis MHOM/BR/75...    28   5.4  

>gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 34
          Length = 2012684

 Score = 77.0 bits (188), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 54/168 (32%), Positives = 91/168 (54%), Gaps = 4/168 (2%)
 Frame = +2

Query: 3       ASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCL 62
               AS+++GDL+  ++E  +   F   G T+++V++ R+ +T    GY +V F +  +AE+ +
Sbjct: 1868852 ASIYVGDLDAAINEPQLVELFKPFG-TILNVRVCRDIITQRSLGYGYVNFDNHHSAERAI 1869028

Query: 63      HKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYS----LFVGDLTPDVDDGMLYEFFVK 118
                 +N + +      K  +L +    +Q D S  YS    +FV +L  DVD   L++ F K
Sbjct: 1869029 ESMNFRRVGD----KCVRLMW----QQRDPSLRYSGNGNVFVKNLEKDVDSKSLHDIFTK 1869184

Query: 119     VYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVGLGSK 166
                + S    KV+ D+ G S+GYGFV F DE+  K A+ +  GA    S+
Sbjct: 1869185 -FGSILSCKVMEDEEGKSRGYGFVHFKDEISAKDAIVKMNGAADHASE 1869325



 Score = 50.1 bits (118), Expect = 2e-06,   Method: Composition-based stats.
 Identities = 28/80 (35%), Positives = 45/80 (56%)
 Frame = +2

Query: 92      NSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQTGVSKGYGFVKFTDELEQK 151
               + P  S++VG L PD+ +  LY++FV++ P       V   T  S GYG+V F D  + +
Sbjct: 1561388 SGPNPSIWVGGLDPDLQEQRLYDYFVRIGPVTSVRVCVDSATQKSLGYGYVNFQDPADAE 1561567

Query: 152     RALTECQGAVGLGSKPVRLS 171
               +AL   Q    LGS+ +R++
Sbjct: 1561568 KALD--QAGTKLGSRYLRIA 1561621



 Score = 48.5 bits (114), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 2/158 (1%)
 Frame = +2

Query: 4       SLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLH 63
               S+W+G L+P + E  +   F  +G  V SV++  +  T    GY +V F D A AEK L 
Sbjct: 1561403 SIWVGGLDPDLQEQRLYDYFVRIG-PVTSVRVCVDSATQKSLGYGYVNFQDPADAEKALD 1561579

Query: 64      KINGKPLPGATPAKRFKLNYATYGKQPDN--SPEYSLFVGDLTPDVDDGMLYEFFVKVYP 121
               +       G     R+ L  A   + P    S   ++ V  L   VD   L E F K + 
Sbjct: 1561580 Q------AGTKLGSRY-LRIAKIQRDPSKRRSGVNNILVKKLPKTVDTYALKELFSK-FG 1561735

Query: 122     SCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQG 159
                     +  D+ G S+GY  + F  E     A+ E  G
Sbjct: 1561736 RLTAIGLACDEKGESRGYARISFEREESAVEAVKEMDG 1561849



 Score = 37.0 bits (84), Expect = 0.016,   Method: Composition-based stats.
 Identities = 45/197 (22%), Positives = 86/197 (43%), Gaps = 16/197 (8%)
 Frame = +2

Query: 4       SLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPA--GYCFVEFADLATAEKC 61
               +L++ +L+P + +  +   FA  G  V S K+    L G+ +  G  +V F     A + 
Sbjct: 1561928 NLYVKNLDPAVTDEKLRAFFARYG-AVSSAKV--RDLGGVQSEVGLGYVAFEKHEDAARA 1562098

Query: 62      LHKINGKPLPGATPAKRFKLN-------------YATYGKQPDNSPEYSLFVGDLTPDVD 108
               + ++NGK    A       ++                  +   +S   +L+V      V 
Sbjct: 1562099 VEELNGKECEIAKAESTLDVSRFRSREERQRDRERQRRERAQQHSKYPNLYVKGFDDTVT 1562278

Query: 109     DGMLYEFFVKVYPSCRGGKVVLD-QTGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKP 167
                  L E F + Y       V++D +TG+S+ +GFV   D+    +A+ E  G+  L  +P
Sbjct: 1562279 SERLEELFQR-YGETVSVTVMMDKETGMSRCFGFVSMKDQNAASQAIQELNGSTFLCPRP 1562455

Query: 168     VRLSVAIPKASRVKPVE 184
               + ++ A+ K +R + +E
Sbjct: 1562456 LFVTYALRKDARRQNLE 1562506



 Score = 29.3 bits (64), Expect = 3.3,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
 Frame = +1

Query: 94     PEYSLFVGDLTPDVDDGMLYEFFVKV-YPSCRGGKVVLD-QTGVSKGYGFVKF 144
              PE S+F+G++  D  +  ++ FF +      +  ++V D +TG  KG+G+V+F
Sbjct: 979723 PETSIFLGNVAYDTTEEDVWNFFQEHGIRDVKRVRLVRDRETGDCKGFGYVEF 979881


>gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 25
          Length = 923860

 Score = 55.5 bits (132), Expect = 4e-08,   Method: Composition-based stats.
 Identities = 52/163 (31%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
 Frame = -2

Query: 4     SLWMGDLEPYMD--ENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC 61
             S+++GDL   +   E  I+  F+++   V+SVK+ R+  T    GY +V F   A AEK 
Sbjct: 21312 SVFVGDLPVDLPRPEEAINNLFSSIA-PVVSVKVCRDIATQRSLGYGYVNFQTTADAEKV 21136

Query: 62    LHKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKV-- 119
             +  +N     G  P +  ++ +A        S   ++FV  L   V    L   F +   
Sbjct: 21135 IDALN---FTGIAPGRYIRVMFAIRDPLQRKSGANNIFVKKLDAAVSAKALQAAFSRCGR 20965

Query: 120   YPSCRGGKVVLDQTGVSKGYGFVKFTDELEQKRALTECQGAVG 162
               SC   KV LD  G SKGYGFV+F      K AL      VG
Sbjct: 20964 VLSC---KVALDSEGHSKGYGFVQFETADGAKAALDMNGAKVG 20845



 Score = 34.7 bits (78), Expect = 0.086,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 38/75 (50%)
 Frame = -3

Query: 10     LEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKP 69
              L P M+E  +   F   G  + SVKII +++TG   GY FV++    +A   +  +N   
Sbjct: 159974 LPPLMNEEQVCELFGQFGR-IESVKIIYDKITGESRGYGFVKYRFYFSATYAVSCLNRFE 159798

Query: 70     LPGATPAKRFKLNYA 84
              + G    K+ K+ YA
Sbjct: 159797 IGG----KKLKVAYA 159765



 Score = 34.3 bits (77), Expect = 0.097,   Method: Composition-based stats.
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = -2

Query: 90     PDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-QTGVSKGYGFVKFTDEL 148
              P+     +L V  +   VD+  L + F + Y      K+V D +T  S+GYGFVK+    
Sbjct: 143379 PEPEALRNLMVNYIPTTVDEMQLRQLFER-YGPIETVKIVCDRETRQSRGYGFVKYCSAA 143203

Query: 149    EQKRALTECQGAVGLGSKPVRLSVAIPKASRVKP 182
                ++A+ E  G   + +K +++++A     R +P
Sbjct: 143202 SAQQAVNELNG-FNILNKRLKVALAASGNQRQRP 143104



 Score = 34.3 bits (77), Expect = 0.10,   Method: Composition-based stats.
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
 Frame = -1

Query: 90     PDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-QTGVSKGYGFVKFTDEL 148
              P+     +L V  +   VD+  L + F + Y      K+V D +T  S+GYGFVK+    
Sbjct: 151888 PEPEALRNLMVNYIPTTVDEMQLRQLFER-YGPIETVKIVCDRETRQSRGYGFVKYCSAA 151712

Query: 149    EQKRALTECQGAVGLGSKPVRLSVAIPKASRVKP 182
                ++A+ E  G   + +K +++++A     R +P
Sbjct: 151711 SAQQAVNELNG-FNILNKRLKVALAASGNQRQRP 151613



 Score = 33.5 bits (75), Expect = 0.20,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 41/76 (53%)
 Frame = -2

Query: 14     MDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGA 73
              +DE  + + F   G  + +VKI+ +R T    GY FV++   A+A++ ++++NG  +   
Sbjct: 143328 VDEMQLRQLFERYG-PIETVKIVCDRETRQSRGYGFVKYCSAASAQQAVNELNGFNILN- 143155

Query: 74     TPAKRFKLNYATYGKQ 89
                 KR K+  A  G Q
Sbjct: 143154 ---KRLKVALAASGNQ 143116



 Score = 33.1 bits (74), Expect = 0.22,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 41/76 (53%)
 Frame = -1

Query: 14     MDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGA 73
              +DE  + + F   G  + +VKI+ +R T    GY FV++   A+A++ ++++NG  +   
Sbjct: 151837 VDEMQLRQLFERYG-PIETVKIVCDRETRQSRGYGFVKYCSAASAQQAVNELNGFNILN- 151664

Query: 74     TPAKRFKLNYATYGKQ 89
                 KR K+  A  G Q
Sbjct: 151663 ---KRLKVALAASGNQ 151625



 Score = 31.6 bits (70), Expect = 0.66,   Method: Composition-based stats.
 Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)
 Frame = -3

Query: 71     PGATPAKRFKLN---------YATYGKQP-DNSPEYSLFVGDLTPDVDDGMLYEFFVKVY 120
              P ++PA+R             ++T+G    D     +L V  L P +++  + E F + +
Sbjct: 160100 PSSSPAQRSNPESVVAAVAGAHSTFGGCAFDPDALRNLIVNYLPPLMNEEQVCELFGQ-F 159924

Query: 121    PSCRGGKVVLDQ-TGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRLSVAIPKASR 179
                    K++ D+ TG S+GYGFVK+        A++ C     +G K ++++ A  +A++
Sbjct: 159923 GRIESVKIIYDKITGESRGYGFVKYRFYFSATYAVS-CLNRFEIGGKKLKVAYANVQAAK 159747


>gi|154335720|ref|NC_009310.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 18
          Length = 708397

 Score = 40.4 bits (93), Expect = 0.002,   Method: Composition-based stats.
 Identities = 38/118 (32%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
 Frame = -1

Query: 57    TAEKCLHKING---KPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLY 113
             TA+K  +K NG   +  P  T A   KLN               L V  L   VDD + +
Sbjct: 92533 TAKKMSYKYNGAYNRGRPSVTTATDSKLN---------------LLVRFLDHTVDD-VQF 92402

Query: 114   EFFVKVYPSCRGGKVVLDQ-TGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRL 170
               F + +       V+ D  TG S+G+GFV+F    +  RAL EC G   +G K V +
Sbjct: 92401 RVFFEPFGDITSSMVMRDIFTGESRGFGFVRFARNADATRALHECDGK-KIGGKAVNV 92231


>gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 30
          Length = 1359875

 Score = 38.5 bits (88), Expect = 0.005,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = -1

Query: 77     KRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-QTGV 135
              + +KL YA   K    +   +LFV  L  ++ D  L + F++ +P+    KV+LD  TG 
Sbjct: 734594 RSYKL*YAV--KTKIMTTLQNLFVAKLPRNLTDADLEQIFLEYHPT--NAKVMLDATTGR 734427

Query: 136    SKGYGFVKFTDE 147
              SKG+GFV F  E
Sbjct: 734426 SKGFGFVLFESE 734391



 Score = 35.8 bits (81), Expect = 0.038,   Method: Composition-based stats.
 Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -2

Query: 97     SLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQ-TGVSKGYGFVKFTDELEQKRA 153
              +LFV  L  ++ D  L   F +  P     K++LD  TG SKG+GFV F +E +  +A
Sbjct: 741214 NLFVAKLPRNISDADLLNIFTEFGPF--SAKIMLDAATGKSKGFGFVLFDEEEKGAKA 741047



 Score = 31.2 bits (69), Expect = 0.96,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 33/69 (47%)
 Frame = -2

Query: 2      AASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC 61
              + ++++G+L  Y  E  +   F+  G  +  + +  N  T  P G+CFV F   A A   
Sbjct: 206368 STTVYVGNLSFYTTEEQLYSHFSPCGH-IRDIVMGLNEATRCPCGFCFVVFESQAAAVLA 206192

Query: 62     LHKINGKPL 70
              +  ++G  L
Sbjct: 206191 VQGLDGSLL 206165



 Score = 27.7 bits (60), Expect = 9.5,   Method: Composition-based stats.
 Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 3/83 (3%)
 Frame = +3

Query: 5      LWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC--- 61
              LW+G+L PY+    ++  F   G      ++ R+ +           F    T E+C   
Sbjct: 392877 LWVGNLVPYITNEKLTEVFEVFGPISSVSRLGRSNMA----------FLHYETVEQCTMA 393026

Query: 62     LHKINGKPLPGATPAKRFKLNYA 84
              +  + G+P+ G        LNY 
Sbjct: 393027 IETMKGRPIEGVM----LSLNYG 393083


>gi|154341365|ref|NC_009321.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 29
          Length = 1190324

 Score = 35.4 bits (80), Expect = 0.052,   Method: Composition-based stats.
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
 Frame = +1

Query: 90      PDNSPEY--SLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-QTGVSKGYGFVKFTD 146
               P N   Y   L V  L  DV    L+  F +  P   G +++ D QT + +GYGFV F  
Sbjct: 1155409 PSNDERYRKQLIVNYLAQDVTSADLHTLFARFGP-LDGARIIFDRQTSMPRGYGFVYFRY 1155585

Query: 147     ELEQKRALTECQG--------AVGLGSKPVRLSVAIP 175
                   K+A+    G         VG  + P+ +  + P
Sbjct: 1155586 PDSAKQAVDSMNGYEFHGKRLKVGYSTNPLNIISSAP 1155696



 Score = 28.5 bits (62), Expect = 5.3,   Method: Composition-based stats.
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = -2

Query: 132     QTGVSKGYGFVKFTDELEQKRAL 154
                TGV  G GFV+++D +E  RAL
Sbjct: 1179325 HTGVGLGTGFVRYSDHMEACRAL 1179257


>gi|154335056|ref|NC_009308.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 16
          Length = 696353

 Score = 33.5 bits (75), Expect = 0.18,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 17/133 (12%)
 Frame = +1

Query: 7      MGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLH--- 63
              M +L P   E  + R FA     V++V+I+R+  TG    Y FVEF  +  A K +    
Sbjct: 647647 MANLHPETVEEDL-RHFADQFGRVLNVRIVRHHKTGKSRRYAFVEFNLVGEARKAIQFHR 647823

Query: 64     ------------KINGKPLPGATPAKRFKLNYATYGKQPDN--SPEYSLFVGDLTPDVDD 109
                          K  G+  PG  P KR +   A++   P N  SP  S+ + +     D 
Sbjct: 647824 KKRLKGYSIIIDKEKGRTEPGFLP-KRLEAA-ASFWTSPANGLSPASSIEMAE-AKRTDS 647994

Query: 110    GMLYEFFVKVYPS 122
                L    +K  PS
Sbjct: 647995 AALGPGSIKAIPS 648033


>gi|154343652|ref|NC_009324.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 32
          Length = 1579615

 Score = 30.8 bits (68), Expect = 1.1,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = -1

Query: 120     YPSCRGGKVVLDQTGVSKGYGFVKFTD 146
               Y   R  K++ D  GVS+GYGF++F +
Sbjct: 1126813 YGPIRNVKLLKDTAGVSRGYGFIEFVN 1126733


>gi|154333023|ref|NC_009301.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 9
          Length = 556710

 Score = 30.8 bits (68), Expect = 1.2,   Method: Composition-based stats.
 Identities = 17/50 (34%), Positives = 30/50 (60%)
 Frame = +2

Query: 132   QTGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRLSVAIPKASRVK 181
             +TG+ KGYGFV F +E +   ++   QG   + +  +++ +A P+AS  K
Sbjct: 16682 KTGLCKGYGFVLFENEQDALNSVIALQGH-SIRNTRIQVRLARPEASAKK 16828



 Score = 28.5 bits (62), Expect = 6.3,   Method: Composition-based stats.
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%)
 Frame = +1

Query: 74    TPAKRFKLNYATYGKQPD-NSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDQ 132
             +P K   L+ +     P   + + +L+V  L     D  L+E F +  P      +    
Sbjct: 35710 SPMKNESLSMSMQASDPAARAYDSNLYVASLPEWFTDADLHELFKRFGPIVSAKVMCHKG 35889

Query: 133   TGVSKGYGFVKFTDELEQKRALTECQGAVGLGSK 166
             T   KGYGFV F    +   A +E  G V  G+K
Sbjct: 35890 THHCKGYGFVLFQHTDDAAVARSEMIGHVVGGNK 35991


>gi|154333356|ref|NC_009302.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 10
          Length = 612479

 Score = 28.5 bits (62), Expect = 5.4,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = -1

Query: 133    TGVSKGYGFVKFTDELEQKRALTECQGAVGLGSKPVRLSVA--IPKASRV 180
              T  +KG  FV+F    +  RAL  C+GA+ +G + +R+S A   P + RV
Sbjct: 330752 TRQNKGAAFVRFFSAEDAVRALRLCRGAILMG-RLLRVSAAEEDPHSKRV 330606


TBLASTN 2.2.17 [Aug-26-2007]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= gi|62821783|ref|NP_082201.2| tRNA selenocysteine associated
protein 1 [Mus musculus]
         (287 letters)

Database: genome.fa 
           35 sequences; 31,379,198 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75...    76   4e-14
gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75...    55   5e-08
gi|154335720|ref|NC_009310.1| Leishmania braziliensis MHOM/BR/75...    40   0.003
gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75...    39   0.006
gi|154335056|ref|NC_009308.1| Leishmania braziliensis MHOM/BR/75...    33   0.18 
gi|154341365|ref|NC_009321.1| Leishmania braziliensis MHOM/BR/75...    32   0.49 
gi|154343652|ref|NC_009324.1| Leishmania braziliensis MHOM/BR/75...    31   1.2  
gi|154333023|ref|NC_009301.1| Leishmania braziliensis MHOM/BR/75...    29   4.5  
gi|154333356|ref|NC_009302.1| Leishmania braziliensis MHOM/BR/75...    29   5.1  
gi|154340161|ref|NC_009319.1| Leishmania braziliensis MHOM/BR/75...    28   8.7  

>gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 34
          Length = 2012684

 Score = 75.9 bits (185), Expect = 4e-14,   Method: Composition-based stats.
 Identities = 53/162 (32%), Positives = 88/162 (54%), Gaps = 4/162 (2%)
 Frame = +2

Query: 3       ASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCL 62
               AS+++GDL+  ++E  +   F   G T+++V++ R+ +T    GY +V F +  +AE+ +
Sbjct: 1868852 ASIYVGDLDAAINEPQLVELFKPFG-TILNVRVCRDIITQRSLGYGYVNFDNHHSAERAI 1869028

Query: 63      HKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYS----LFVGDLTPDVDDGMLYEFFVK 118
                 +N + +      K  +L +    +Q D S  YS    +FV +L  DVD   L++ F K
Sbjct: 1869029 ESMNFRRVGD----KCVRLMW----QQRDPSLRYSGNGNVFVKNLEKDVDSKSLHDIFTK 1869184

Query: 119     VYPSCRGGKVVLDPTGVSKGYGFVKFTDELEQKRALTECQGA 160
                + S    KV+ D  G S+GYGFV F DE+  K A+ +  GA
Sbjct: 1869185 -FGSILSCKVMEDEEGKSRGYGFVHFKDEISAKDAIVKMNGA 1869307



 Score = 48.5 bits (114), Expect = 5e-06,   Method: Composition-based stats.
 Identities = 27/80 (33%), Positives = 44/80 (55%)
 Frame = +2

Query: 92      NSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDPTGVSKGYGFVKFTDELEQK 151
               + P  S++VG L PD+ +  LY++FV++ P       V   T  S GYG+V F D  + +
Sbjct: 1561388 SGPNPSIWVGGLDPDLQEQRLYDYFVRIGPVTSVRVCVDSATQKSLGYGYVNFQDPADAE 1561567

Query: 152     RALTECQGAVGLGCKPVRLS 171
               +AL   Q    LG + +R++
Sbjct: 1561568 KALD--QAGTKLGSRYLRIA 1561621



 Score = 48.1 bits (113), Expect = 7e-06,   Method: Composition-based stats.
 Identities = 46/158 (29%), Positives = 66/158 (41%), Gaps = 2/158 (1%)
 Frame = +2

Query: 4       SLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLH 63
               S+W+G L+P + E  +   F  +G  V SV++  +  T    GY +V F D A AEK L 
Sbjct: 1561403 SIWVGGLDPDLQEQRLYDYFVRIG-PVTSVRVCVDSATQKSLGYGYVNFQDPADAEKALD 1561579

Query: 64      KINGKPLPGATPAKRFKLNYATYGKQPDN--SPEYSLFVGDLTPDVDDGMLYEFFVKVYP 121
               +       G     R+ L  A   + P    S   ++ V  L   VD   L E F K + 
Sbjct: 1561580 Q------AGTKLGSRY-LRIAKIQRDPSKRRSGVNNILVKKLPKTVDTYALKELFSK-FG 1561735

Query: 122     SCRGGKVVLDPTGVSKGYGFVKFTDELEQKRALTECQG 159
                     +  D  G S+GY  + F  E     A+ E  G
Sbjct: 1561736 RLTAIGLACDEKGESRGYARISFEREESAVEAVKEMDG 1561849



 Score = 28.1 bits (61), Expect = 7.6,   Method: Composition-based stats.
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
 Frame = +1

Query: 94     PEYSLFVGDLTPDVDDGMLYEFFVKV-YPSCRGGKVVLD-PTGVSKGYGFVKF 144
              PE S+F+G++  D  +  ++ FF +      +  ++V D  TG  KG+G+V+F
Sbjct: 979723 PETSIFLGNVAYDTTEEDVWNFFQEHGIRDVKRVRLVRDRETGDCKGFGYVEF 979881


>gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 25
          Length = 923860

 Score = 55.5 bits (132), Expect = 5e-08,   Method: Composition-based stats.
 Identities = 52/163 (31%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
 Frame = -2

Query: 4     SLWMGDLEPYMD--ENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC 61
             S+++GDL   +   E  I+  F+++   V+SVK+ R+  T    GY +V F   A AEK 
Sbjct: 21312 SVFVGDLPVDLPRPEEAINNLFSSIA-PVVSVKVCRDIATQRSLGYGYVNFQTTADAEKV 21136

Query: 62    LHKINGKPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKV-- 119
             +  +N     G  P +  ++ +A        S   ++FV  L   V    L   F +   
Sbjct: 21135 IDALN---FTGIAPGRYIRVMFAIRDPLQRKSGANNIFVKKLDAAVSAKALQAAFSRCGR 20965

Query: 120   YPSCRGGKVVLDPTGVSKGYGFVKFTDELEQKRALTECQGAVG 162
               SC   KV LD  G SKGYGFV+F      K AL      VG
Sbjct: 20964 VLSC---KVALDSEGHSKGYGFVQFETADGAKAALDMNGAKVG 20845



 Score = 34.7 bits (78), Expect = 0.082,   Method: Composition-based stats.
 Identities = 24/75 (32%), Positives = 38/75 (50%)
 Frame = -3

Query: 10     LEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKP 69
              L P M+E  +   F   G  + SVKII +++TG   GY FV++    +A   +  +N   
Sbjct: 159974 LPPLMNEEQVCELFGQFGR-IESVKIIYDKITGESRGYGFVKYRFYFSATYAVSCLNRFE 159798

Query: 70     LPGATPAKRFKLNYA 84
              + G    K+ K+ YA
Sbjct: 159797 IGG----KKLKVAYA 159765



 Score = 33.1 bits (74), Expect = 0.22,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 41/76 (53%)
 Frame = -1

Query: 14     MDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGA 73
              +DE  + + F   G  + +VKI+ +R T    GY FV++   A+A++ ++++NG  +   
Sbjct: 151837 VDEMQLRQLFERYG-PIETVKIVCDRETRQSRGYGFVKYCSAASAQQAVNELNGFNILN- 151664

Query: 74     TPAKRFKLNYATYGKQ 89
                 KR K+  A  G Q
Sbjct: 151663 ---KRLKVALAASGNQ 151625



 Score = 33.1 bits (74), Expect = 0.24,   Method: Composition-based stats.
 Identities = 23/76 (30%), Positives = 41/76 (53%)
 Frame = -2

Query: 14     MDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLHKINGKPLPGA 73
              +DE  + + F   G  + +VKI+ +R T    GY FV++   A+A++ ++++NG  +   
Sbjct: 143328 VDEMQLRQLFERYG-PIETVKIVCDRETRQSRGYGFVKYCSAASAQQAVNELNGFNILN- 143155

Query: 74     TPAKRFKLNYATYGKQ 89
                 KR K+  A  G Q
Sbjct: 143154 ---KRLKVALAASGNQ 143116



 Score = 32.0 bits (71), Expect = 0.48,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = -1

Query: 90     PDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-PTGVSKGYGFVKFTDEL 148
              P+     +L V  +   VD+  L + F + Y      K+V D  T  S+GYGFVK+    
Sbjct: 151888 PEPEALRNLMVNYIPTTVDEMQLRQLFER-YGPIETVKIVCDRETRQSRGYGFVKYCSAA 151712

Query: 149    EQKRALTECQGAVGLGCKPVRLSVAIPKASRVKP 182
                ++A+ E  G   L  K +++++A     R +P
Sbjct: 151711 SAQQAVNELNGFNILN-KRLKVALAASGNQRQRP 151613



 Score = 32.0 bits (71), Expect = 0.53,   Method: Composition-based stats.
 Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
 Frame = -2

Query: 90     PDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-PTGVSKGYGFVKFTDEL 148
              P+     +L V  +   VD+  L + F + Y      K+V D  T  S+GYGFVK+    
Sbjct: 143379 PEPEALRNLMVNYIPTTVDEMQLRQLFER-YGPIETVKIVCDRETRQSRGYGFVKYCSAA 143203

Query: 149    EQKRALTECQGAVGLGCKPVRLSVAIPKASRVKP 182
                ++A+ E  G   L  K +++++A     R +P
Sbjct: 143202 SAQQAVNELNGFNILN-KRLKVALAASGNQRQRP 143104



 Score = 29.6 bits (65), Expect = 2.3,   Method: Composition-based stats.
 Identities = 30/120 (25%), Positives = 57/120 (47%), Gaps = 11/120 (9%)
 Frame = -3

Query: 71     PGATPAKRFKLN---------YATYGKQP-DNSPEYSLFVGDLTPDVDDGMLYEFFVKVY 120
              P ++PA+R             ++T+G    D     +L V  L P +++  + E F + +
Sbjct: 160100 PSSSPAQRSNPESVVAAVAGAHSTFGGCAFDPDALRNLIVNYLPPLMNEEQVCELFGQ-F 159924

Query: 121    PSCRGGKVVLDP-TGVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASR 179
                    K++ D  TG S+GYGFVK+        A++ C     +G K ++++ A  +A++
Sbjct: 159923 GRIESVKIIYDKITGESRGYGFVKYRFYFSATYAVS-CLNRFEIGGKKLKVAYANVQAAK 159747


>gi|154335720|ref|NC_009310.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 18
          Length = 708397

 Score = 39.7 bits (91), Expect = 0.003,   Method: Composition-based stats.
 Identities = 35/107 (32%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
 Frame = -1

Query: 57    TAEKCLHKING---KPLPGATPAKRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLY 113
             TA+K  +K NG   +  P  T A   KLN               L V  L   VDD + +
Sbjct: 92533 TAKKMSYKYNGAYNRGRPSVTTATDSKLN---------------LLVRFLDHTVDD-VQF 92402

Query: 114   EFFVKVYPSCRGGKVVLDP-TGVSKGYGFVKFTDELEQKRALTECQG 159
               F + +       V+ D  TG S+G+GFV+F    +  RAL EC G
Sbjct: 92401 RVFFEPFGDITSSMVMRDIFTGESRGFGFVRFARNADATRALHECDG 92261



 Score = 32.3 bits (72), Expect = 0.40,   Method: Composition-based stats.
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
 Frame = +3

Query: 98     LFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDPTGVSKGYGFVKFTDELEQKRALTEC 157
              LFVG +     +  L   F + + S    K++ +P G SKG  +V++  E   +RA++  
Sbjct: 243984 LFVGQVPAVCTEDQLRPLFAQ-FGSLLEIKIMREPNGRSKGSAWVRYESEESAQRAISSL 244160

Query: 158    --QGAVGLGCKPVRLSVAIPKASRVKPV 183
                +  V     P+R+  A P  +R+  V
Sbjct: 244161 NEKHVVPPQTNPLRVQFAAPSTNRMSQV 244244


>gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 30
          Length = 1359875

 Score = 38.5 bits (88), Expect = 0.006,   Method: Composition-based stats.
 Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = -1

Query: 77     KRFKLNYATYGKQPDNSPEYSLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDPT-GV 135
              + +KL YA   K    +   +LFV  L  ++ D  L + F++ +P+    KV+LD T G 
Sbjct: 734594 RSYKL*YAV--KTKIMTTLQNLFVAKLPRNLTDADLEQIFLEYHPT--NAKVMLDATTGR 734427

Query: 136    SKGYGFVKFTDE 147
              SKG+GFV F  E
Sbjct: 734426 SKGFGFVLFESE 734391



 Score = 35.8 bits (81), Expect = 0.038,   Method: Composition-based stats.
 Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
 Frame = -2

Query: 97     SLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLDP-TGVSKGYGFVKFTDELEQKRA 153
              +LFV  L  ++ D  L   F +  P     K++LD  TG SKG+GFV F +E +  +A
Sbjct: 741214 NLFVAKLPRNISDADLLNIFTEFGPF--SAKIMLDAATGKSKGFGFVLFDEEEKGAKA 741047



 Score = 31.2 bits (69), Expect = 0.96,   Method: Composition-based stats.
 Identities = 18/69 (26%), Positives = 33/69 (47%)
 Frame = -2

Query: 2      AASLWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC 61
              + ++++G+L  Y  E  +   F+  G  +  + +  N  T  P G+CFV F   A A   
Sbjct: 206368 STTVYVGNLSFYTTEEQLYSHFSPCGH-IRDIVMGLNEATRCPCGFCFVVFESQAAAVLA 206192

Query: 62     LHKINGKPL 70
              +  ++G  L
Sbjct: 206191 VQGLDGSLL 206165



 Score = 27.7 bits (60), Expect = 9.9,   Method: Composition-based stats.
 Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 3/83 (3%)
 Frame = +3

Query: 5      LWMGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKC--- 61
              LW+G+L PY+    ++  F   G      ++ R+ +           F    T E+C   
Sbjct: 392877 LWVGNLVPYITNEKLTEVFEVFGPISSVSRLGRSNMA----------FLHYETVEQCTMA 393026

Query: 62     LHKINGKPLPGATPAKRFKLNYA 84
              +  + G+P+ G        LNY 
Sbjct: 393027 IETMKGRPIEGVM----LSLNYG 393083


>gi|154335056|ref|NC_009308.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 16
          Length = 696353

 Score = 33.5 bits (75), Expect = 0.18,   Method: Composition-based stats.
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 17/133 (12%)
 Frame = +1

Query: 7      MGDLEPYMDENFISRAFATMGETVMSVKIIRNRLTGIPAGYCFVEFADLATAEKCLH--- 63
              M +L P   E  + R FA     V++V+I+R+  TG    Y FVEF  +  A K +    
Sbjct: 647647 MANLHPETVEEDL-RHFADQFGRVLNVRIVRHHKTGKSRRYAFVEFNLVGEARKAIQFHR 647823

Query: 64     ------------KINGKPLPGATPAKRFKLNYATYGKQPDN--SPEYSLFVGDLTPDVDD 109
                          K  G+  PG  P KR +   A++   P N  SP  S+ + +     D 
Sbjct: 647824 KKRLKGYSIIIDKEKGRTEPGFLP-KRLEAA-ASFWTSPANGLSPASSIEMAE-AKRTDS 647994

Query: 110    GMLYEFFVKVYPS 122
                L    +K  PS
Sbjct: 647995 AALGPGSIKAIPS 648033


>gi|154341365|ref|NC_009321.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 29
          Length = 1190324

 Score = 32.0 bits (71), Expect = 0.49,   Method: Composition-based stats.
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 11/97 (11%)
 Frame = +1

Query: 90      PDNSPEY--SLFVGDLTPDVDDGMLYEFFVKVYPSCRGGKVVLD-PTGVSKGYGFVKFTD 146
               P N   Y   L V  L  DV    L+  F +  P   G +++ D  T + +GYGFV F  
Sbjct: 1155409 PSNDERYRKQLIVNYLAQDVTSADLHTLFARFGP-LDGARIIFDRQTSMPRGYGFVYFRY 1155585

Query: 147     ELEQKRALTECQG--------AVGLGCKPVRLSVAIP 175
                   K+A+    G         VG    P+ +  + P
Sbjct: 1155586 PDSAKQAVDSMNGYEFHGKRLKVGYSTNPLNIISSAP 1155696



 Score = 28.5 bits (62), Expect = 6.2,   Method: Composition-based stats.
 Identities = 12/22 (54%), Positives = 16/22 (72%)
 Frame = -2

Query: 133     TGVSKGYGFVKFTDELEQKRAL 154
               TGV  G GFV+++D +E  RAL
Sbjct: 1179322 TGVGLGTGFVRYSDHMEACRAL 1179257


>gi|154343652|ref|NC_009324.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 32
          Length = 1579615

 Score = 30.8 bits (68), Expect = 1.2,   Method: Composition-based stats.
 Identities = 12/27 (44%), Positives = 18/27 (66%)
 Frame = -1

Query: 120     YPSCRGGKVVLDPTGVSKGYGFVKFTD 146
               Y   R  K++ D  GVS+GYGF++F +
Sbjct: 1126813 YGPIRNVKLLKDTAGVSRGYGFIEFVN 1126733


>gi|154333023|ref|NC_009301.1| Leishmania braziliensis MHOM/BR/75/M2904
             chromosome 9
          Length = 556710

 Score = 28.9 bits (63), Expect = 4.5,   Method: Composition-based stats.
 Identities = 17/49 (34%), Positives = 28/49 (57%)
 Frame = +2

Query: 133   TGVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVK 181
             TG+ KGYGFV F +E +   ++   QG   +    +++ +A P+AS  K
Sbjct: 16685 TGLCKGYGFVLFENEQDALNSVIALQGH-SIRNTRIQVRLARPEASAKK 16828


>gi|154333356|ref|NC_009302.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 10
          Length = 612479

 Score = 28.9 bits (63), Expect = 5.1,   Method: Composition-based stats.
 Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
 Frame = -1

Query: 133    TGVSKGYGFVKFTDELEQKRALTECQGAVGLGCKPVRLSVA--IPKASRV 180
              T  +KG  FV+F    +  RAL  C+GA+ +G + +R+S A   P + RV
Sbjct: 330752 TRQNKGAAFVRFFSAEDAVRALRLCRGAILMG-RLLRVSAAEEDPHSKRV 330606


>gi|154340161|ref|NC_009319.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 27
          Length = 1217395

 Score = 27.7 bits (60), Expect = 8.7,   Method: Composition-based stats.
 Identities = 16/43 (37%), Positives = 22/43 (51%)
 Frame = -3

Query: 140    GFVKFTDELEQKRALTECQGAVGLGCKPVRLSVAIPKASRVKP 182
              GF+K    L Q   L E  G   LGC   RL + +  +SR++P
Sbjct: 554894 GFLKHEPLLPQSHVLYEEAGVDVLGCL*PRLVIPLKLSSRLEP 554766