Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= EhSep2_emiliania_huxley; gi|182639182|sp|Q50KB1.2|SEP2_EMIHU RecName: Full=Protein disulfide-isomerase-like protein EhSep2; Flags: Precursor # QUERY (223 letters) Database: genome.fa 35 sequences; 31,379,198 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|140256453|ref|NC_009276.1| Leishmania braziliensis MHOM/BR/75... 84 1e-16 gi|154346825|ref|NC_009327.1| Leishmania braziliensis MHOM/BR/75... 69 3e-12 gi|154336958|ref|NC_009312.1| Leishmania braziliensis MHOM/BR/75... 64 7e-11 gi|154339612|ref|NC_009318.1| Leishmania braziliensis MHOM/BR/75... 53 2e-07 gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75... 37 0.009 gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75... 33 0.11 gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75... 33 0.18 gi|154337694|ref|NC_009314.1| Leishmania braziliensis MHOM/BR/75... 28 4.3 >gi|140256453|ref|NC_009276.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 6 Length = 526431 Score = 83.6 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 38/106 (35%), Positives = 61/106 (57%), Gaps = 1/106 (0%) Frame = +3 Query: 17 AGAIELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVD 76 A +EL P NF ++V K F+ F APW GHC MKP W LA + S+ ++IA +D Sbjct: 433797 AEMVELNPANFHKIVKDPSKNVFVMFYAPWCGHCNNMKPVWLELADNYPISEDIIIARID 433976 Query: 77 CTTGGKPLCEKYGVRGYPTIKYFNPPDEEGED-YKGGRSLDELKKF 121 + + + +++G+ G+PT+K+F D+ G + Y G R L + + Sbjct: 433977 -ASAYRGIAKEFGISGFPTLKFFPKRDKSGANQYSGPRELSAFRSY 434111 Score = 58.9 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Frame = +2 Query: 20 IELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWD--SLASTFEDSKKVLIADVDC 77 +ELT D FD V S K F+ + W CK M WD S++ + ++ ++V A Sbjct: 479162 VELTRDTFDAHVSGSDKYTFVLYCVKWSRQCKTMIRLWDRLSISQSKKELREVFTAAYVD 479341 Query: 78 TTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKF 121 L E+ V+G+PT+ ++ P EG +Y G R L L F Sbjct: 479342 GDKYPDLVERVNVKGFPTMLFYTPLHTEGLEYNGPRELYLLDSF 479473 >gi|154346825|ref|NC_009327.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 35 Length = 2686796 Score = 68.6 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 42/110 (38%), Positives = 61/110 (55%) Frame = -1 Query: 23 TPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGK 82 T DNFD +V SG +KF APW GHCK + P++ A + +A+VDCTT K Sbjct: 2670119 TQDNFDNVV--SGDLTLVKFYAPWCGHCKTLAPEFVKAAEML--TGIATLAEVDCTT-EK 2669955 Query: 83 PLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFAENELGPGCSV 132 L EKY V+G+PT+ F + + Y G R+ D + + ++ +GP V Sbjct: 2669954 ALAEKYEVKGFPTLYVFR-NGVKVKAYDGPRTADGIASYMKSHVGPSMKV 2669808 Score = 64.7 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 35/85 (41%), Positives = 53/85 (62%) Frame = -1 Query: 42 FLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLCEKYGVRGYPTIKYFNP 101 F APW GHC+K+ PD++ +A + S+ V+IA +D TT EK+ V G+PTI YF P Sbjct: 2669066 FYAPWCGHCQKLHPDYEKMAENLQ-SENVMIAKMDATTNDFDR-EKFQVSGFPTI-YFIP 2668896 Query: 102 PDEEGEDYKGGRSLDELKKFAENEL 126 + Y+GGRS E+++F + + Sbjct: 2668895 AGKPPMMYEGGRSAKEMEEFVRSHM 2668821 >gi|154336958|ref|NC_009312.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 20 Length = 1668259 Score = 64.3 bits (155), Expect = 7e-11, Method: Composition-based stats. Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 3/158 (1%) Frame = -3 Query: 14 GASAGAIELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIA 73 G S+ ELT + + V + K I F APW GHCK+ P+++ A + +V Sbjct: 718181 GKSSAVTELTSSSLNAFV-NTHKPVVILFYAPWCGHCKQFHPEFERFAQLMKGIIRVGAI 718005 Query: 74 DVDCTTGGKPLCEKYGVRGYPTIKYFNPPDE---EGEDYKGGRSLDELKKFAENELGPGC 130 D D T + +++GVRG+PTIKY+ + +DY+G R+ L+ E+ Sbjct: 718004 DADRNTH---IGQQFGVRGFPTIKYWRSGAKSVSSAQDYQGQRTAAALQSLMIGEIS--- 717843 Query: 131 SVDLMDNCSEEQKGKLKEYIDMAPEKRTEMLETLKKEL 168 S ++ + E+ +K +P+K +L +LK ++ Sbjct: 717842 SSEVTKVTTAEE---IKHAARNSPKKMIGVLLSLKNKV 717738 >gi|154339612|ref|NC_009318.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 26 Length = 1008282 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 6/119 (5%) Frame = -3 Query: 15 ASAGAIELTPDNFDELVLKSGKAAFI--KFLAPWUGHCKKMKPDWDSLASTF----EDSK 68 A G ++ +N+ ++V G F+ +F A W GHC+K P ++ E Sbjct: 181129 AMGGVEDVNSENYYDIV---GHDQFVLLEFYAVWCGHCRKFSPIYEEFGKYIRIRPELQG 180959 Query: 69 KVLIADVDCTTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFAENELG 127 +V++ V+ T + +C +Y + GYPT+ P G ++ R+ + L F E E+ Sbjct: 180958 RVVVGKVNAPTEPR-ICRRYRISGYPTVILVPPNRHVGVEFTDNRNFNGLLDFVEREMA 180785 Score = 47.4 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 2/109 (1%) Frame = -2 Query: 21 ELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTG 80 EL NFD ++ +A F+ F PW K + ++ LA F K V+IA +D + Sbjct: 179294 ELEHINFDSVINDPSRAVFVMFYLPWTPESKNLMLIYNDLAKVFLGDKDVVIARIDVSDV 179115 Query: 81 GKPLCEKYGVRGYPTIKYFNPPDEEGE--DYKGGRSLDELKKFAENELG 127 KY + P++ YF P E Y+ L+ L F G Sbjct: 179114 SSKYMVKYNILETPSV-YFFPKGANAEPVKYRRRHHLEGLVAFVNKRAG 178971 >gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 30 Length = 1359875 Score = 37.4 bits (85), Expect = 0.009, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 1/70 (1%) Frame = +1 Query: 31 VLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLC-EKYG 89 V +S + F A W G C+++KP ++ +A ++ SK + C C +YG Sbjct: 363412 VQRSDVVTVVDFYADWCGPCQQIKPQFEQMAQYYDPSKVIF---AKCNVDRNRDCASRYG 363582 Query: 90 VRGYPTIKYF 99 V PT F Sbjct: 363583 VTSIPTFIVF 363612 >gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 25 Length = 923860 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 32/71 (45%) Frame = -3 Query: 29 ELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLCEKY 88 + +++ K I F A W G CK + P + LAST + DVD T + Y Sbjct: 201509 QALVRQPKLTVIDFFATWCGPCKSIAPLIEKLAST-KPHVNFAKVDVDRTPD---VVRNY 201342 Query: 89 GVRGYPTIKYF 99 VR PT +F Sbjct: 201341 PVRAMPTFYFF 201309 >gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 34 Length = 2012684 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 9/112 (8%) Frame = +3 Query: 20 IELTPDNFDELVLKSGKAAFIKFL----APWUGHCKKMKPDWDSLASTFEDSKKV----- 70 + L NF+ + S A FL +PW HCK + P + + AS D +V Sbjct: 495576 VVLNNANFEPYLFPSKHATPRAFLVLCYSPWCSHCKALLPQFLN-ASLQLDLMRVPHSTF 495752 Query: 71 LIADVDCTTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFA 122 + DV T + E + V +PT+ Y D + Y+G + + +F+ Sbjct: 495753 AVVDVQKNTA---VSEYFNVERFPTLLYTTGKDRQWHLYEGSNTQEGFMQFS 495899 >gi|154337694|ref|NC_009314.1| Leishmania braziliensis MHOM/BR/75/M2904 chromosome 22 Length = 657844 Score = 28.5 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 25/47 (53%) Frame = +2 Query: 162 ETLKKELADAESTHEALLKELQATYKESMDKLEKLKEESAPKIKLLK 208 E ++E DAE A L E + Y+ES +L+ L+E + LL+ Sbjct: 350804 ERTRQEAIDAEKMTSAQLDEYRVRYEESKRQLDLLRERMQSTMSLLE 350944