Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= EhSep2_emiliania_huxley; gi|182639182|sp|Q50KB1.2|SEP2_EMIHU
RecName: Full=Protein disulfide-isomerase-like protein EhSep2; Flags:
Precursor # QUERY
         (223 letters)

Database: genome.fa 
           35 sequences; 31,379,198 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|140256453|ref|NC_009276.1| Leishmania braziliensis MHOM/BR/75...    84   1e-16
gi|154346825|ref|NC_009327.1| Leishmania braziliensis MHOM/BR/75...    69   3e-12
gi|154336958|ref|NC_009312.1| Leishmania braziliensis MHOM/BR/75...    64   7e-11
gi|154339612|ref|NC_009318.1| Leishmania braziliensis MHOM/BR/75...    53   2e-07
gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75...    37   0.009
gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75...    33   0.11 
gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75...    33   0.18 
gi|154337694|ref|NC_009314.1| Leishmania braziliensis MHOM/BR/75...    28   4.3  

>gi|140256453|ref|NC_009276.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 6
          Length = 526431

 Score = 83.6 bits (205), Expect = 1e-16,   Method: Composition-based stats.
 Identities = 38/106 (35%), Positives = 61/106 (57%), Gaps = 1/106 (0%)
 Frame = +3

Query: 17     AGAIELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVD 76
              A  +EL P NF ++V    K  F+ F APW GHC  MKP W  LA  +  S+ ++IA +D
Sbjct: 433797 AEMVELNPANFHKIVKDPSKNVFVMFYAPWCGHCNNMKPVWLELADNYPISEDIIIARID 433976

Query: 77     CTTGGKPLCEKYGVRGYPTIKYFNPPDEEGED-YKGGRSLDELKKF 121
                +  + + +++G+ G+PT+K+F   D+ G + Y G R L   + +
Sbjct: 433977 -ASAYRGIAKEFGISGFPTLKFFPKRDKSGANQYSGPRELSAFRSY 434111



 Score = 58.9 bits (141), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
 Frame = +2

Query: 20     IELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWD--SLASTFEDSKKVLIADVDC 77
              +ELT D FD  V  S K  F+ +   W   CK M   WD  S++ + ++ ++V  A    
Sbjct: 479162 VELTRDTFDAHVSGSDKYTFVLYCVKWSRQCKTMIRLWDRLSISQSKKELREVFTAAYVD 479341

Query: 78     TTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKF 121
                    L E+  V+G+PT+ ++ P   EG +Y G R L  L  F
Sbjct: 479342 GDKYPDLVERVNVKGFPTMLFYTPLHTEGLEYNGPRELYLLDSF 479473


>gi|154346825|ref|NC_009327.1| Leishmania braziliensis MHOM/BR/75/M2904
               chromosome 35
          Length = 2686796

 Score = 68.6 bits (166), Expect = 3e-12,   Method: Composition-based stats.
 Identities = 42/110 (38%), Positives = 61/110 (55%)
 Frame = -1

Query: 23      TPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGK 82
               T DNFD +V  SG    +KF APW GHCK + P++   A     +    +A+VDCTT  K
Sbjct: 2670119 TQDNFDNVV--SGDLTLVKFYAPWCGHCKTLAPEFVKAAEML--TGIATLAEVDCTT-EK 2669955

Query: 83      PLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFAENELGPGCSV 132
                L EKY V+G+PT+  F     + + Y G R+ D +  + ++ +GP   V
Sbjct: 2669954 ALAEKYEVKGFPTLYVFR-NGVKVKAYDGPRTADGIASYMKSHVGPSMKV 2669808



 Score = 64.7 bits (156), Expect = 5e-11,   Method: Composition-based stats.
 Identities = 35/85 (41%), Positives = 53/85 (62%)
 Frame = -1

Query: 42      FLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLCEKYGVRGYPTIKYFNP 101
               F APW GHC+K+ PD++ +A   + S+ V+IA +D TT      EK+ V G+PTI YF P
Sbjct: 2669066 FYAPWCGHCQKLHPDYEKMAENLQ-SENVMIAKMDATTNDFDR-EKFQVSGFPTI-YFIP 2668896

Query: 102     PDEEGEDYKGGRSLDELKKFAENEL 126
                 +    Y+GGRS  E+++F  + +
Sbjct: 2668895 AGKPPMMYEGGRSAKEMEEFVRSHM 2668821


>gi|154336958|ref|NC_009312.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 20
          Length = 1668259

 Score = 64.3 bits (155), Expect = 7e-11,   Method: Composition-based stats.
 Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 3/158 (1%)
 Frame = -3

Query: 14     GASAGAIELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIA 73
              G S+   ELT  + +  V  + K   I F APW GHCK+  P+++  A   +   +V   
Sbjct: 718181 GKSSAVTELTSSSLNAFV-NTHKPVVILFYAPWCGHCKQFHPEFERFAQLMKGIIRVGAI 718005

Query: 74     DVDCTTGGKPLCEKYGVRGYPTIKYFNPPDE---EGEDYKGGRSLDELKKFAENELGPGC 130
              D D  T    + +++GVRG+PTIKY+    +     +DY+G R+   L+     E+    
Sbjct: 718004 DADRNTH---IGQQFGVRGFPTIKYWRSGAKSVSSAQDYQGQRTAAALQSLMIGEIS--- 717843

Query: 131    SVDLMDNCSEEQKGKLKEYIDMAPEKRTEMLETLKKEL 168
              S ++    + E+   +K     +P+K   +L +LK ++
Sbjct: 717842 SSEVTKVTTAEE---IKHAARNSPKKMIGVLLSLKNKV 717738


>gi|154339612|ref|NC_009318.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 26
          Length = 1008282

 Score = 52.8 bits (125), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 31/119 (26%), Positives = 56/119 (47%), Gaps = 6/119 (5%)
 Frame = -3

Query: 15     ASAGAIELTPDNFDELVLKSGKAAFI--KFLAPWUGHCKKMKPDWDSLASTF----EDSK 68
              A  G  ++  +N+ ++V   G   F+  +F A W GHC+K  P ++          E   
Sbjct: 181129 AMGGVEDVNSENYYDIV---GHDQFVLLEFYAVWCGHCRKFSPIYEEFGKYIRIRPELQG 180959

Query: 69     KVLIADVDCTTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFAENELG 127
              +V++  V+  T  + +C +Y + GYPT+    P    G ++   R+ + L  F E E+ 
Sbjct: 180958 RVVVGKVNAPTEPR-ICRRYRISGYPTVILVPPNRHVGVEFTDNRNFNGLLDFVEREMA 180785



 Score = 47.4 bits (111), Expect = 8e-06,   Method: Composition-based stats.
 Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
 Frame = -2

Query: 21     ELTPDNFDELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTG 80
              EL   NFD ++    +A F+ F  PW    K +   ++ LA  F   K V+IA +D +  
Sbjct: 179294 ELEHINFDSVINDPSRAVFVMFYLPWTPESKNLMLIYNDLAKVFLGDKDVVIARIDVSDV 179115

Query: 81     GKPLCEKYGVRGYPTIKYFNPPDEEGE--DYKGGRSLDELKKFAENELG 127
                    KY +   P++ YF P     E   Y+    L+ L  F     G
Sbjct: 179114 SSKYMVKYNILETPSV-YFFPKGANAEPVKYRRRHHLEGLVAFVNKRAG 178971


>gi|154342106|ref|NC_009322.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 30
          Length = 1359875

 Score = 37.4 bits (85), Expect = 0.009,   Method: Composition-based stats.
 Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 1/70 (1%)
 Frame = +1

Query: 31     VLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLC-EKYG 89
              V +S     + F A W G C+++KP ++ +A  ++ SK +      C       C  +YG
Sbjct: 363412 VQRSDVVTVVDFYADWCGPCQQIKPQFEQMAQYYDPSKVIF---AKCNVDRNRDCASRYG 363582

Query: 90     VRGYPTIKYF 99
              V   PT   F
Sbjct: 363583 VTSIPTFIVF 363612


>gi|154339085|ref|NC_009317.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 25
          Length = 923860

 Score = 33.5 bits (75), Expect = 0.11,   Method: Composition-based stats.
 Identities = 23/71 (32%), Positives = 32/71 (45%)
 Frame = -3

Query: 29     ELVLKSGKAAFIKFLAPWUGHCKKMKPDWDSLASTFEDSKKVLIADVDCTTGGKPLCEKY 88
              + +++  K   I F A W G CK + P  + LAST +        DVD T     +   Y
Sbjct: 201509 QALVRQPKLTVIDFFATWCGPCKSIAPLIEKLAST-KPHVNFAKVDVDRTPD---VVRNY 201342

Query: 89     GVRGYPTIKYF 99
               VR  PT  +F
Sbjct: 201341 PVRAMPTFYFF 201309


>gi|154345382|ref|NC_009326.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 34
          Length = 2012684

 Score = 33.1 bits (74), Expect = 0.18,   Method: Composition-based stats.
 Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 9/112 (8%)
 Frame = +3

Query: 20     IELTPDNFDELVLKSGKAAFIKFL----APWUGHCKKMKPDWDSLASTFEDSKKV----- 70
              + L   NF+  +  S  A    FL    +PW  HCK + P + + AS   D  +V     
Sbjct: 495576 VVLNNANFEPYLFPSKHATPRAFLVLCYSPWCSHCKALLPQFLN-ASLQLDLMRVPHSTF 495752

Query: 71     LIADVDCTTGGKPLCEKYGVRGYPTIKYFNPPDEEGEDYKGGRSLDELKKFA 122
               + DV   T    + E + V  +PT+ Y    D +   Y+G  + +   +F+
Sbjct: 495753 AVVDVQKNTA---VSEYFNVERFPTLLYTTGKDRQWHLYEGSNTQEGFMQFS 495899


>gi|154337694|ref|NC_009314.1| Leishmania braziliensis MHOM/BR/75/M2904
              chromosome 22
          Length = 657844

 Score = 28.5 bits (62), Expect = 4.3,   Method: Composition-based stats.
 Identities = 16/47 (34%), Positives = 25/47 (53%)
 Frame = +2

Query: 162    ETLKKELADAESTHEALLKELQATYKESMDKLEKLKEESAPKIKLLK 208
              E  ++E  DAE    A L E +  Y+ES  +L+ L+E     + LL+
Sbjct: 350804 ERTRQEAIDAEKMTSAQLDEYRVRYEESKRQLDLLRERMQSTMSLLE 350944