CLUSTAL W (1.83) multiple sequence alignment


transcript2      GCCTTCCTGGGATTGGAGTCTCGAGCTTTCTTCGTTCGTTCGTCGGCGGGTTCGCGCCCT 60
transcript3      GCCTTCCTGGGATTGGAGTCTCGAGCTTTCTTCGTTCGTTCGTCGGCGGGTTCGCGCCCT 60
transcript1      GCCTTCCTGGGATTGGAGTCTCGAGCTTTCTTCGTTCGTTCGTCGGCGGGTTCGCGCCCT 60
                 ************************************************************

transcript2      TCTCGCGCCTCGGGGCTGCGAGGCTGGGGAAGGGGTTGGAGGGGGCTGTTGATCGCCGCG 120
transcript3      TCTCGCGCCTCGGGGCTGCGAGGCTGGGGAAGGGGTTGGAGGGGGCTGTTGATCGCCGCG 120
transcript1      TCTCGCGCCTCGGGGCTGCGAGGCTGGGGAAGGGGTTGGAGGGGGCTGTTGATCGCCGCG 120
                 ************************************************************

transcript2      TTTAAGTTGCGCTCGGGGCGGCCATGTCGGCCGGCGAGGTCGAGCGCCTAGTGTCGGAGC 180
transcript3      TTTAAGTTGCGCTCGGGGCGGCCATGTCGGCCGGCGAGGTCGAGCGCCTAGTGTCGGAGC 180
transcript1      TTTAAGTTGCGCTCGGGGCGGCCATGTCGGCCGGCGAGGTCGAGCGCCTAGTGTCGGAGC 180
                 ************************************************************

transcript2      TGAGCGGCGGGACCGGAGGGGATGAGGAGGAAGAGTGGCTCTATGGCGGCCCATGGGACG 240
transcript3      TGAGCGGCGGGACCGGAGGGGATGAGGAGGAAGAGTGGCTCTATGGCGGCCCATGGGACG 240
transcript1      TGAGCGGCGGGACCGGAGGGGATGAGGAGGAAGAGTGGCTCTATGGCG------------ 228
                 ************************************************            

transcript2      TGCATGTGCACAGTGATTTGGCAAAGGACCTAGATGAAAATGAAGTTGAAAGGCCAGAAG 300
transcript3      TGCATGTGCACAGTGATTTGGCAAAGGACCTAGATGAAAATGAAGTTGAAAGGCCAGAAG 300
transcript1      ---------------------------------ATGAAAATGAAGTTGAAAGGCCAGAAG 255
                                                  ***************************

transcript2      AAGAAAATGCCAGTGCTAATCCTCCATCTGGAATTGAAGATGAAACTGCTGAAAATGGTG 360
transcript3      AAGAAAATGCCAGTGCTAATCCTCCATCTGGAATTGAAGATGAAACTGCTGAAAATGGTG 360
transcript1      AAGAAAATGCCAGTGCTAATCCTCCATCTGGAATTGAAGATGAAACTGCTGAAAATGGTG 315
                 ************************************************************

transcript2      TACCAAAACCGAAAGTGACTGAGACCGAAGATGATAGTGATAGTGACAGCGATGATGATG 420
transcript3      TACCAAAACCGAAAGTGACTGAGACCGAAGATGATAGTGATAGTGACAGCGATGATGATG 420
transcript1      TACCAAAACCGAAAGTGACTGAGACCGAAGATGATAGTGATAGTGACAGCGATGATGATG 375
                 ************************************************************

transcript2      AAGATGATGTTCATGTCACTATAGGAGACATTAAAACGGGAGCACCACAGTATGGGAGTT 480
transcript3      AAGATGATGTTCATGTCACTATAGGAGACATTAAAACGGGAGCACCACAGTATGGGAGTT 480
transcript1      AAGATGATGTTCATGTCACTATAGGAGACATTAAAACGGGAGCACCACAGTATGGGAGTT 435
                 ************************************************************

transcript2      ATGGTACAGCACCTGTAAATCTTAACATCAAGACAGGGGGAAGAGTTTATGGAACTACAG 540
transcript3      ATGGTACAGCACCTGTAAATCTTAACATCAAGACAGGGGGAAGAGTTTATGGAACTACAG 540
transcript1      ATGGTACAGCACCTGTAAATCTTAACATCAAGACAGGGGGAAGAGTTTATGGAACTACAG 495
                 ************************************************************

transcript2      GGACAAAAGTCAAAGGAGTAGACCTTGATGCACCTGGAAGCATTAATGGAGTTCCACTCT 600
transcript3      GGACAAAAGTCAAAGGAGTAGACCTTGATGCACCTGGAAGCATTAATGGAGTTCCACTCT 600
transcript1      GGACAAAAGTCAAAGGAGTAGACCTTGATGCACCTGGAAGCATTAATGGAGTTCCACTCT 555
                 ************************************************************

transcript2      TAGAGGTAGATTTGGATTCTTTTGAAGATAAACCATGGCGTAAACCTGGTGCTGATCTTT 660
transcript3      TAGAGGTAGATTTGGATTCTTTTGAAGATAAACCATGGCGTAAACCTGGTGCTGATCTTT 660
transcript1      TAGAGGTAGATTTGGATTCTTTTGAAGATAAACCATGGCGTAAACCTGGTGCTGATCTTT 615
                 ************************************************************

transcript2      CTGATTATTTTAATTATGGGTTTAATGAAGATACCTGGAAAGCTTACTGTGAAAAACAAA 720
transcript3      CTGATTATTTTAATTATGGGTTTAATGAAGATACCTGGAAAGCTTACTGTGAAAAACAAA 720
transcript1      CTGATTATTTTAATTATGGGTTTAATGAAGATACCTGGAAAGCTTACTGTGAAAAACAAA 675
                 ************************************************************

transcript2      AGAGGATACGAATGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGG 780
transcript3      AGAGGATACGAATGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGG 780
transcript1      AGAGGATACGAATGGGACTTGAAGTTATACCAGTAACCTCTACTACAAATAAAATTACGG 735
                 ************************************************************

transcript2      CCGAAGACTGTACTATGGAAGTTACACCAGGTGCAGAGATCCAAGATGGCAGATTCAATC 840
transcript3      CCGAAGACTGTACTATGGAAGTTACACCAGGTGCAGAGATCCAAGATGGCAGATTCAATC 840
transcript1      ------------------------------------------------------------
                                                                             

transcript2      TTTTTAAGGTACAGCAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTA 900
transcript3      TTTTTAAGGTACAGCAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTA 900
transcript1      ---------TACAGCAGGGAAGAACTGGAAACTCAGAGAAAGAAACTGCCCTTCCATCTA 786
                          ***************************************************

transcript2      CAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGAA 960
transcript3      CAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAGAA 960
transcript1      CAAAAGCTGAGTTTACTTCTCCTCCTTCTTTGTTCAAGACTGGGCTTCCACCGAGCAG-- 844
                 **********************************************************  

transcript2      ACAGCACTTCTTCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTG 1020
transcript3      ACAGCACTTCTTCTCAGTCTCAGACAAGTACTGCCTCCAGAAAAGCCAATTCAAGCGTTG 1020
transcript1      ------------------------------------------------------------
                                                                             

transcript2      GGAAGTGGCAGGATCGATATGGGAGGGCCGAATCACCTGATCTAAGGAGATTACCTGGGG 1080
transcript3      GGAAGTGGCAGGATCGATATGGGAGGGCCGAATCACCTGATCTAAGGAGATTACCTGGGG 1080
transcript1      ----------------------------------------------GAGATTACCTGGGG 858
                                                               **************

transcript2      CAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAA 1140
transcript3      CAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAA 1140
transcript1      CAATTGATGTTATCGGTCAGACTATAACTATCAGCCGAGTAGAAGGCAGGCGACGGGCAA 918
                 ************************************************************

transcript2      ATGAGAACAGCAACATACAGGTCCTTTCTGAAAGATCTGCTACTGAAGTAGACAACAATT 1200
transcript3      ATGAGAACAGCAACATACAGGTCCTTTCTGAAAGATCTGCTACTGAAGTAGACAACAATT 1200
transcript1      ATGAGAACAGCAACATACAGGTCCTTTCTGAAAGATCTGCTACTGAAGTAGACAACAATT 978
                 ************************************************************

transcript2      TTAGCAAACCACCTCCGTTTTTCCCTCCAGGAGCTCCTCCCACTCACCTTCCACCTCCTC 1260
transcript3      TTAGCAAACCACCTCCGTTTTTCCCTCCAGGAGCTCCTCCCACTCACCTTCCACCTCCTC 1260
transcript1      TTAGCAAACCACCTCCGTTTTTCCCTCCAGGAGCTCCTCCCACTCACCTTCCACCTCCTC 1038
                 ************************************************************

transcript2      CATTTCTTCCACCTCCTCCGACTGTCAGCACTGCTCCACCTCTGATTCCACCACCGGGTT 1320
transcript3      CATTTCTTCCACCTCCTCCGACTGTCAGCACTGCTCCACCTCTGATTCCACCACCGGGTT 1320
transcript1      CATTTCTTCCACCTCCTCCGACTGTCAGCACTGCTCCACCTCTGATTCCACCACCGGGTT 1098
                 ************************************************************

transcript2      TTCCTCCTCCACCAGGCGCTCCACCTCCATCTCTTATACCAACAATAGAAAGTGGACATT 1380
transcript3      TTCCTCCTCCACCAGGCGCTCCACCTCCATCTCTTATACCAACAATAGAAAGTGGACATT 1380
transcript1      TTCCTCCTCCACCAGGCGCTCCACCTCCATCTCTTATACCAACAATAGAAAGTGGACATT 1158
                 ************************************************************

transcript2      CCTCTGGTTATGATAGTCGTTCTGCACGTGCATTTCCATATGGCAATGTTGCCTTTCCCC 1440
transcript3      CCTCTGGTTATGATAGTCGTTCTGCACGTGCATTTCCATATGGCAATGTTGCCTTTCCCC 1440
transcript1      CCTCTGGTTATGATAGTCGTTCTGCACGTGCATTTCCATATGGCAATGTTGCCTTTCCCC 1218
                 ************************************************************

transcript2      ATCTTCCTGGTTCTGCTCCTTCGTGGCCTAGTCTTGTGGACACCAGCAAGCAGTGGGACT 1500
transcript3      ATCTTCCTGGTTCTGCTCCTTCGTGGCCTAGTCTTGTGGACACCAGCAAGCAGTGGGACT 1500
transcript1      ATCTTCCTGGTTCTGCTCCTTCGTGGCCTAGTCTTGTGGACACCAGCAAGCAGTGGGACT 1278
                 ************************************************************

transcript2      ATTATGCCAGAAGAGAGAAAGACCGAGATAGAGAGAGAGACAGAGACAGAGAGCGAGACC 1560
transcript3      ATTATGCCAGAAGAGAGAAAGACCGAGATAGAGAGAGAGACAGAGACAGAGAGCGAGACC 1560
transcript1      ATTATGCCAGAAGAGAGAAAGACCGAGATAGAGAGAGAGACAGAGACAGAGAGCGAGACC 1338
                 ************************************************************

transcript2      GTGATCGGGACAGAGAAAGAGAACGCACCAGAGAGAGAGAGAGGGAGCGTGATCACAGTC 1620
transcript3      GTGATCGGGACAGAGAAAGAGAACGCACCAGAGAGAGAGAGAGGGAGCGTGATCACAGTC 1620
transcript1      GTGATCGGGACAGAGAAAGAGAACGCACCAGAGAGAGAGAGAGGGAGCGTGATCACAGTC 1398
                 ************************************************************

transcript2      CTACACCAAGTGTTTTCAACAGCGATGAAGAACGATACAGATACAGGGAATATGCAGAAA 1680
transcript3      CTACACCAAGTGTTTTCAACAGCGATGAAGAACGATACAGATACAGGGAATATGCAGAAA 1680
transcript1      CTACACCAAGTGTTTTCAACAGCGATGAAGAACGATACAGATACAGGGAATATGCAGAAA 1458
                 ************************************************************

transcript2      GAGGTTATGAGCGTCACAGAGCAAGTCGAGAAAAAGAAGAACGACATAGAGAAAGACGAC 1740
transcript3      GAGGTTATGAGCGTCACAGAGCAAGTCGAGAAAAAGAAGAACGACATAGAGAAAGACGAC 1740
transcript1      GAGGTTATGAGCGTCACAGAGCAAGTCGAGAAAAAGAAGAACGACATAGAGAAAGACGAC 1518
                 ************************************************************

transcript2      ACAGGGAGAAAGAGGAAACCAGACATAAGTCTTCTCGAAGTAATAGTAGACGTCGCCATG 1800
transcript3      ACAGGGAGAAAGAGGAAACCAGACATAAGTCTTCTCGAAGTAATAGTAGACGTCGCCATG 1800
transcript1      ACAGGGAGAAAGAGGAAACCAGACATAAGTCTTCTCGAAGTAATAGTAGACGTCGCCATG 1578
                 ************************************************************

transcript2      AAAGTGAAGAAGGAGATAGTCACAGGAGACACAAACACAAAAAATCTAAAAGAAGCAAAG 1860
transcript3      AAAGTGAAGAAGGAGATAGTCACAGGAGACACAAACACAAAAAATCTAAAAGAAGCAAAG 1860
transcript1      AAAGTGAAGAAGGAGATAGTCACAGGAGACACAAACACAAAAAATCTAAAAGAAGCAAAG 1638
                 ************************************************************

transcript2      AAGGAAAAGAAGCGGGCAGTGAGCCTGCCCCTGAACAGGAGAGCACCGAAGCTACACCTG 1920
transcript3      AAGGAAAAGAAGCGGGCAGTGAGCCTGCCCCTGAACAGGAGAGCACCGAAGCTACACCTG 1920
transcript1      AAGGAAAAGAAGCGGGCAGTGAGCCTGCCCCTGAACAGGAGAGCACCGAAGCTACACCTG 1698
                 ************************************************************

transcript2      CAGAATAGGCATGGTTTTGGCCTTTTGTGTATATTAGTACCAGAAGTAGATACTATAAAT 1980
transcript3      CAGAATAGGCATGGTTTTGGCCTTTTGTGTATATTAGTACCAGAAGTAGATACTATAAAT 1980
transcript1      CAGAATAGGCATGGTTTTGGCCTTTTGTGTATATTAGTACCAGAAGTAGATACTATAAAT 1758
                 ************************************************************

transcript2      CTTGTTATTTTTCTGGATAATGTTTAAGAAATTTACCTTAAATCTTGTTCTGTTTGTTAG 2040
transcript3      CTTGTTATTTTTCTGGATAATGTTTAAGAAATTTACCTTAAATCTTGTTCTGTTTGTTAG 2040
transcript1      CTTGTTATTTTTCTGGATAATGTTTAAGAAATTTACCTTAAATCTTGTTCTGTTTGTTAG 1818
                 ************************************************************

transcript2      TATGAAAAGTTAACTTTTTTTCCAAAATAAAAGAGTGAATTTTTCATGTTAAGTTAAAAA 2100
transcript3      TATGAAAAGTTAACTTTTTTTCCAAAATAAAAGAGTGAATTTTTCATGTTAAGTTAAAAA 2100
transcript1      TATGAAAAGTTAACTTTTTTTCCAAAATAAAAGAGTGAATTTTTCATGTTAAGTTAAAAA 1878
                 ************************************************************

transcript2      TCTTTGTCTTGTACTATTTCAAAAATAAAAAGACAGCAATGACTTTATATCCAA 2154
transcript3      ------------------------------------------------------
transcript1      TCTTTGTCTTGTACTATTTCAAAAATAAAAAGACAGCAATGACTTTATATCCAA 1932
                                                                       

Here we can see the alignment between the three transcripts of FIP1L1. As we have said before, the transcript number 1 doesn't have exons number 2, 9 and 11. We have marked in green the place where transcript 2 and 3 have exon 2 and transcript number 1 hasn't; in red the place where transcript 2 and 3 have exon 9 and transcript number 1 hasn't; and finally, in blue the place where transcript 2 and 3 have exon 11 and transcript number 1 hasn't. In yellow we have marked the absence of 54 nucleotides in transcript number 3, wheareas transcript number two has this 54 nucleotides.