MKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQKLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEERE YKCDQCPKAFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLC RHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFSFSFPGL FPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKHPSVGDNKPVELQPERSSEERPFEKISDQSESSDLDDVSTPSGSDLETT SGSDLESDIESDKEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLP FFPAFSQSMYPFPDRDLRSLPLKMEPQSPGEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKLTEPRKNHVFGGK KGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLESFSALKPEASELLQSVPSMFNF RAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGN MSGTATSSPHSELESTGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKDEKALVTSQNSDLLDDEEVEDEVLLDEEDEDNDITGKTGKEPVT SNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALDHIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKES LHSTSHSSSNVWHSMARAAAESSAIQSISHV
Aquest gen codifica per la isoforma més llarga de la proteïna EVI1. Aquest transcrit principal conté 16 exons dels quals els 2 primers no són codificants juntament amb una petita regió del 3 i del 16. D'aquesta manera ens queden 14 exons codificants. A partir d'aquest transcrit es compararà com és l'estructura exònica de la isoforma curta.
| acgt | seqüència intrònica | acgt | seqüència 5' upstream i 3' downstream |
| ACGT | seqüència exònica codificant | ACGT | seqüència exònica no codificant (UTRs) |
| Regió | N° nucleotids | Seqüència |
| 5' upstream | caaaatctgaattcctggcactggccacgcgactttggagccgctctcggccgagttcca |
|
| Exó 1 | 80 | CCTTGCCAAGTAACAGCTTTGCTGTCCAACATCGTGTGCTGCTTCGCGAGAAAGTCACAT TCGGACCCTTTGGCTAGATT |
| Intró 1-2 | 2.393 | gtggggatttttttttttttccttttgctgttggttttttgaaagggcctttctctaaag ............................................................ tgattattttaatgagtgggccaatatggcaattgattgttctcatcttcttccctccag |
| Exó 2 | 135 | ATCTTAGACGAATTTTACAATGTGAAGTTCTGCATAGATGCCAGTCAACCAGATGTTGGA AGCTGGCTCAAGTACATTAGATTCGCTGGCTGTTATGATCAGCACAACCTTGTTGCATGC CAGATAAATGATCAG |
| Intró 2-3 | 12.166 | gtatgttgtaaagattttcttgtctttccttgagagcacaaaagtatcactggagcctga ............................................................ gttaatatatatacatctctctctttcctgattccatccacctttattttgtctttaaag |
| Exó 3 | 103 | ATATTCTATAGAGTAGTTGCAGACATTGCGCCGGGAGAGGAGCTTCTGCTGTTCATGAAG AGCGAAGACTATCCCCATGAAACTATGGCGCCGGATATCCACG |
| Intró 3-4 | 3.368 | gttagtaccactcacgccaccctccttatcaccttatcatcgcgactataaagtagcatc ............................................................ ggctggtttgtgatggcaattcctgaccacccaatcctaacacctgaattgttttcacag |
| Exó 4 | 217 | AAGAACGGCAATATCGCTGCGAAGACTGTGACCAGCTCTTTGAATCTAAGGCTGAACTAG CAGATCACCAAAAGTTTCCATGCAGTACTCCTCACTCAGCATTTTCAATGGTTGAAGAGG ACTTTCAGCAAAAACTCGAAAGCGAGAATGATCTCCAAGAGATACACACGATCCAGGAGT GTAAGGAATGTGACCAAGTTTTTCCTGATTTGCAAAG |
| Intró 4-5 | 5.116 | gttagaaatggcatgttgtaccatacaacttgtgtattttttctgcaatgttatgctgaa ............................................................ aatgttgttccgtttatgaatgcatcctttgtcttttaaaatctattgttctcttaacag |
| Exó 5 | 148 | CCTGGAGAAACACATGCTGTCACATACTGAAGAGAGGGAATACAAGTGTGATCAGTGTCC CAAGGCATTTAACTGGAAGTCCAATTTAATTCGCCACCAGATGTCACATGACAGTGGAAA GCACTATGAATGTGAAAACTGTGCCAAG |
| Intró 5-6 | 1.370 | gtacagtgaatttgtaggctacttggcctctctatgtcatcctgctctctcttaatccat ............................................................ tcttctttattgtgcccttgagttaagtttcttgattaatcagtactcatttcctagcag |
| Exó 6 | 154 | GTTTTCACGGACCCTAGCAACCTTCAGCGGCACATTCGCTCTCAGCATGTCGGTGCCCGG GCCCATGCATGCCCGGAGTGTGGCAAAACGTTTGCCACTTCGTCGGGCCTCAAACAACAC AAGCACATCCACAGCAGTGTGAAGCCCTTTATCT |
| Intró 6-7 | 4.316 | gtaagttttcaacactccagccctccttcccacatctgtctcttccccaaaaggcactgt ............................................................ tgctaaattcagaagcaattgacataaagcctgagattcttttttgttgtttgcacacag |
| Exó 7 | 1.357 | GTGAGGTCTGCCATAAATCCTATACTCAGTTTTCAAACCTTTGCCGTCATAAGCGCATGC ATGCTGATTGCAGAACCCAAATCAAGTGCAAAGACTGTGGACAAATGTTCAGCACTACGT CTTCCTTAAATAAACACAGGAGGTTTTGTGAGGGCAAGAACCATTTTGCGGCAGGTGGAT TTTTTGGCCAAGGCATTTCACTTCCTGGAACCCCAGCTATGGATAAAACGTCCATGGTTA ATATGAGTCATGCCAACCCGGGCCTTGCTGACTATTTTGGCGCCAATAGGCATCCTGCTG GTCTTACCTTTCCAACAGCTCCTGGATTTTCTTTTAGCTTCCCTGGTCTGTTTCCTTCCG GCTTGTACCACAGGCCTCCTTTGATACCTGCTAGTTCTCCTGTTAAAGGACTATCAAGTA CTGAACAGACAAACAAAAGTCAAAGTCCCCTCATGACACATCCTCAGATACTGCCAGCTA CACAGGATATTTTGAAGGCACTATCTAAACACCCATCTGTAGGGGACAATAAGCCAGTGG AGCTCCAGCCCGAGAGGTCCTCTGAAGAGAGGCCCTTTGAGAAAATCAGTGACCAGTCAG AGAGTAGTGACCTTGATGATGTCAGTACACCAAGTGGCAGTGACCTGGAAACAACCTCGG GCTCTGATCTGGAAAGTGACATTGAAAGTGATAAAGAGAAATTTAAAGAAAATGGTAAAA TGTTCAAAGACAAAGTAAGCCCTCTTCAGAATCTGGCTTCAATAAATAATAAGAAAGAAT ACAGCAATCATTCCATTTTCTCACCATCTTTAGAGGAGCAGACTGCGGTGTCAGGAGCTG TGAATGATTCTATAAAGGCTATTGCTTCTATTGCTGAAAAATACTTTGGTTCAACAGGAC TGGTGGGGCTGCAAGACAAAAAAGTTGGAGCTTTACCTTACCCTTCCATGTTTCCCCTCC CATTTTTTCCAGCATTCTCTCAATCAATGTACCCATTTCCTGATAGAGACTTGAGATCGT TACCTTTGAAAATGGAACCCCAATCACCAGGTGAAGTAAAGAAACTGCAGAAGGGCAGCT CTGAGTCCCCCTTTGATCTCACCACTAAGCGAAAGGATGAGAAGCCCTTGACTCCAGTCC CCTCCAAGCCTCCAGTGACACCTGCCACAAGCCAAGACCAGCCCCTGGATCTAAGTATGG GCAGTAGGAGTAGAGCCAGTGGGACAAAGCTGACTGAGCCTCGAAAAAACCACGTGTTTG GGGGAAAAAAAGGAAGCAACGTCGAATCAAGACCTGCTTCAGATGGTTCCTTGCAGCATG CAAGACCCACTCCTTTCTTTATGGACCCTATTTACAG |
| Intró 7-8 | 2.508 | gtaagcgtgtatggaagatgacgaaatatgagcagatgtatgaaaggcggtatttccact ............................................................ ttatgtagtgattgatatgtgagactgcttcatctccaaaatctaattttaacctttcag |
| Exó 8 | 88 | AGTAGAGAAAAGAAAACTAACTGACCCACTTGAAGCTTTAAAAGAGAAATACTTGAGGCC TTCTCCAGGATTCTTGTTTCACCCACAA |
| Intró 8-9 | 4.834 | gtaagtattttggatttgagatttccagcttgtaaactaacttgttgatcctgaaaagca ............................................................ ttgcaataaagataccaacacagaagtaattttttgtttttgtttcaattttgctcccag |
| Exó 9 | 27 | TTCCAACTGCCTGATCAGAGAACTTGG |
| Intró 9-10 | 5.699 | gtaagtttcctacttatatttttgactaaagtgatgtagcattaaaaagaaaacagctta ............................................................ gagattattatagaagacaagatgccaaacgcttcatggtcttgtgcttttacctttcag |
| Exó 10 | 167 | ATGTCAGCTATTGAAAACATGGCAGAAAAGCTAGAGAGCTTCAGTGCCCTGAAACCTGAG GCCAGTGAGCTCTTACAGTCAGTGCCCTCTATGTTCAACTTCAGGGCGCCTCCCAATGCC CTGCCAGAGAACCTTCTGCGGAAGGGAAAGGAGCGCTATACCTGCAG |
| Intró 10-11 | 1.097 | gtaactgcacagttaattatggctgactttccagaaatctcccctctgatttcaaaaggt ............................................................ gcatgagtgaaatatagtcaactgtgctgactttctcttataaacatcttttcataacag |
| Exó 11 | 78 | ATACTGTGGCAAGATTTTTCCAAGGTCTGCAAACCTAACACGGCACTTGAGAACCCACAC AGGAGAGCAGCCTTACAG |
| Intró 11-12 | 5.639 | gtctgacaatgatatttgctaaatatcttgataaatattgtaataattaaagtttatttt ............................................................ tagtcttgagaaataccttttaatgtgcttgctaatattttctctttgtttatttttcag |
| Exó 12 | 170 | ATGCAAATACTGTGACAGATCATTTAGCATATCTTCTAACTTGCAAAGGCATGTTCGCAA CATCCACAATAAAGAGAAGCCATTTAAGTGTCACTTATGTGATAGGTGTTTTGGTCAACA AACCAATTTAGACAGACACCTAAAGAAACATGAGAATGGGAACATGTCCG |
| Intró 12-13 | 1.973 | gtacgtaataaattgtgttataagtcaaagatgacttctttttcgtgttttaaaagataa ............................................................ ccaaataagttgctagataaacaataatctttgtcataaaaggctttctgctccacacag |
| Exó 13 | 145 | GTACAGCAACATCGTCGCCTCATTCTGAACTGGAAAGTACAGGTGCGATTCTGGATGACA AAGAAGATGCTTACTTCACAGAAATTCGAAATTTCATTGGGAACAGCAACCATGGCAGCC AATCTCCCAGGAATGTGGAGGAGAG |
| Intró 13-14 | 2.721 | gtaaagctgtcttttactttttaaactctgtgacgactgaaatgaacatgttttaaaata ............................................................ caaattacaattttaaaaatgaaaccaacaattggactttttttttaatgcttttgaaag |
| Exó 14 | 237 | AATGAATGGCAGTCATTTTAAAGATGAAAAGGCTTTGGTGACCAGTCAAAATTCAGACTT GCTGGATGATGAAGAAGTTGAAGATGAGGTGTTGTTAGATGAGGAGGATGAAGACAATGA TATTACTGGAAAAACAGGAAAGGAACCAGTGACAAGTAATTTACATGAAGGAAACCCTGA GGATGACTATGAAGAAACCAGTGCCCTGGAGATGAGTTGCAAGACATCCCCAGTGAG |
| Intró 14-15 | 816 | gtgagtaccttgggtgactttagaaactaagctagagtagatccatgtacggttgcaatt ............................................................ tgatttgattagataacaaatgaaaagaaaatttctgtgtttttcgttggttcattttag |
| Exó 15 | 184 | GTATAAAGAGGAAGAATATAAAAGTGGACTTTCTGCTCTAGATCATATAAGGCACTTCAC AGATAGCCTCAAAATGAGGAAAATGGAAGATAATCAATATTCTGAAGCTGAGCTGTCTTC TTTTAGTACTTCCCATGTGCCAGAGGAACTTAAGCAGCCGTTACACAGAAAGTCCAAATC GCAG |
| Intró 15-16 | 3.956 | gtacagattttcccatagtacagcatcatggttacattatgcatgaaacgtacatttcct ............................................................ tgaactaaaagtgatgtttttcaaatgccatttactgagtctctctcctttttaccccag |
| Exó 16 | 282 | GCATATGCTATGATGCTGTCACTGTCTGACAAGGAGTCCCTCCATTCTACATCCCACAGT TCTTCCAACGTGTGGCACAGTATGGCCAGGGCTGCGGCGGAATCCAGTGCTATCCAGTCC ATAAGCCACGTATGACGTTATCAAGGTTGACCAGAGTGGGACCAAGTCCAACAGTAGCAT GGCTCTTTCATATAGGACTATTTACAAGACTGCTGAGCAGAATGCCTTATAAACCTGCAG GGTCACTCATCTAAAGTCTAGTGACCTTAAACTGAATGATTT |
| 3' downstream | aaaaaagaaaagaaagaaaaaagaaactatttattctcgatattttgttttgcacagcaa |
