Transcrit ENST00000325074

Seqüència de la proteïna:

MPAAPRGPAQGEAAARTRSRDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHW
RCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGP
REPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASP
SVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGS
SQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY

Esquema dels exons:

A diferència del transcrit principal aquest presenta 7 exons. D'aquests exons, els 6 últims són idèntics als 6 últims exons del transcrit principal. Només varia el primer exó que no presenta regions no codificants i es troba a la regió intrònica entre l'exó 2 i 3 del transcrit principal.

Localització al cromosoma 21:   35,183,904 - 35,081,975

Seqüència nucleotídica:

acgt seqüència intrònica acgt seqüència 5' upstream i 3' downstream
ACGT seqüència exònica codificant ACGT seqüència exònica no codificant (UTRs)

Regió N° nucleotids Seqüència
5' upstream
cggggtcggagttggcagcgcacgccggaccgggggcggggccctccgagctccgcgaaa
Exó 1 61
ATGCCCGCAGCACCGCGGGGACCGGCGCAGGGGGAAGCGGCCGCCCGCACGCGAAGCCGG
G
Intró 1-2 2.580
gtgggttccgcacctggggccgctcgagcgcacgggggcggggagaggagcgggggccgc
............................................................
ggtaggagctgtttgcagggtcctaactcaatcggcttgttgtgatgcgtatccccgtag
Exó 2 254
ATGCCAGCACGAGCCGCCGCTTCACGCCGCCTTCCACCGCGCTGAGCCCAGGCAAGATGA
GCGAGGCGTTGCCGCTGGGCGCCCCGGACGCCGGCGCTGCCCTGGCCGGCAAGCTGAGGA
GCGGCGACCGCAGCATGGTGGAGGTGCTGGCCGACCACCCGGGCGAGCTGGTGCGCACCG
ACAGCCCCAACTTCCTCTGCTCCGTGCTGCCTACGCACTGGCGCTGCAACAAGACCCTGC
CCATCGCTTTCAAG
Intró 2-3 6.129
gtactggcccggagagggtggtgggaggacaggcggaggccggcgaggccgggggagatc
............................................................
ccctaaaagtgtatgtataacatccctgatgtctgcatttgtcctttgactggtgtttag
Exó 3 157

GTGGTGGCCCTAGGGGATGTTCCAGATGGCACTCTGGTCACTGTGATGGCTGGCAATGAT
GAAAACTACTCGGCTGAGCTGAGAAATGCTACCGCAGCCATGAAGAACCAGGTTGCAAGA
TTTAATGACCTCAGGTTTGTCGGTCGAAGTGGAAGAG
Intró 3-4 20.978
gtacgttatctgtcaaaactatgcttgaaacacgtttcatggcaacaaacccacatttca
............................................................
caacagatatgttcaggccaccaacctcattctgttttgttctctatcgtgtccccacag
Exó 4 105
GGAAAAGCTTCACTCTGACCATCACTGTCTTCACAAACCCACCGCAAGTCGCCACCTACC
ACAGAGCCATCAAAATCACAGTGGATGGGCCCCGAGAACCTCGAA
Intró 4-5 24.872
gtaagtgcatccacttggggctggtacaccctccaggctggtacaccctccaggctggta
............................................................
gatctcttccctccctccttccctccccccatcccctcccctccctgctccccacaatag
Exó 5 192
GACATCGGCAGAAACTAGATGATCAGACCAAGCCCGGGAGCTTGTCCTTTTCCGAGCGGC
TCAGTGAACTGGAGCAGCTGCGGCGCACAGCCATGAGGGTCAGCCCACACCACCCAGCCC
CCACGCCCAACCCTCGTGCCTCCCTGAACCACTCCACTGCCTTTAACCCTCAGCCTCAGA
GTCAGATGCAGG
Intró 5-6 34.947
gtaagtaccagatggagcccactgcccgcctctcctgcacctgggccaccacccacaact
............................................................
aagacattttttaaatcccaccccactttacatataattgacctttctgattctcttcag
Exó 6 162
ATACAAGGCAGATCCAACCATCCCCACCGTGGTCCTACGATCAGTCCTACCAATACCTGG
GATCCATTGCCTCTCCTTCTGTGCACCCAGCAACGCCCATTTCACCTGGACGTGCCAGCG
GCATGACAACCCTCTCTGCAGAACTTTCCAGTCGACTCTCAA
Intró 6-7 6.690
gtaagccacttgaaaacacattctttgcagctgagctggggtggaaggtccaggagacta
............................................................
gagctgtggcctccgcaacctcctactcacttccgctccgttctcttgcccgccctgcag
Exó 7 4.803
CGGCACCCGACCTGACAGCGTTCAGCGACCCGCGCCAGTTCCCCGCGCTGCCCTCCATCT
CCGACCCCCGCATGCACTATCCAGGCGCCTTCACCTACTCCCCGACGCCGGTCACCTCGG
GCATCGGCATCGGCATGTCGGCCATGGGCTCGGCCACGCGCTACCACACCTACCTGCCGC
CGCCCTACCCCGGCTCGTCGCAAGCGCAGGGAGGCCCGTTCCAAGCCAGCTCGCCCTCCT
ACCACCTGTACTACGGCGCCTCGGCCGGCTCCTACCAGTTCTCCATGGTGGGCGGCGAGC
GCTCGCCGCCGCGCATCCTGCCGCCCTGCACCAACGCCTCCACCGGCTCCGCGCTGCTCA
ACCCCAGCCTCCCGAACCAGAGCGACGTGGTGGAGGCCGAGGGCAGCCACAGCAACTCCC
CCACCAACATGGCGCCCTCCGCGCGCCTGGAGGAGGCCGTGTGGAGGCCCTACTGAGGCG
CCAGGCCTGGCCCGGCTGGGCCCCGCGGGCCGCCGCCTTCGCCTCCGGGCGCGCGGGCCT
CCTGTTCGCGACAAGCCCGCCGGGATCCCGGGCCCTGGGCCCGGCCACCGTCCTGGGGCC
GAGGGCGCCCGACGGCCAGGATCTCGCTGTAGGTCAGGCCCGCGCAGCCTCCTGCGCCCA
GAAGCCCACGCCGCCGCCGTCTGCTGGCGCCCCGGCCCTCGCGGAGGTGTCCGAGGCGAC
GCACCTCGAGGGTGTCCGCCGGCCCCAGCACCCAGGGGACGCGCTGGAAAGCAAACAGGA
AGATTCCCGGAGGGAAACTGTGAATGCTTCTGATTTAGCAATGCTGTGAATAAAAAGAAA
GATTTTATACCCTTGACTTAACTTTTTAACCAAGTTGTTTATTCCAAAGAGTGTGGAATT
TTGGTTGGGGTGGGGGGAGAGGAGGGATGCAACTCGCCCTGTTTGGCATCTAATTCTTAT
TTTTAATTTTTCCGCACCTTATCAATTGCAAAATGCGTATTTGCATTTGGGTGGTTTTTA
TTTTTATATACGTTTATATAAATATATATAAATTGAGCTTGCTTCTTTCTTGCTTTGACC
ATGGAAAGAAATATGATTCCCTTTTCTTTAAGTTTTATTTAACTTTTCTTTTGGACTTTT
GGGTAGTTGTTTTTTTTTGTTTTGTTTTGTTTTTTTGAGAAACAGCTACAGCTTTGGGTC
ATTTTTAACTACTGTATTCCCACAAGGAATCCCCAGATATTTATGTATCTTGATGTTCAG
ACATTTATGTGTTGATAATTTTTTAATTATTTAAATGTACTTATATTAAGAAAAATATCA
AGTACTACATTTTCTTTTGTTCTTGATAGTAGCCAAAGTTAAATGTATCACATTGAAGAA
GGCTAGAAAAAAAGAATGAGTAATGTGATCGCTTGGTTATCCAGAAGTATTGTTTACATT
AAACTCCCTTTCATGTTAATCAAACAAGTGAGTAGCTCACGCAGCAACGTTTTTAATAGG
ATTTTTAGACACTGAGGGTCACTCCAAGGATCAGAAGTATGGAATTTTCTGCCAGGCTCA
ACAAGGGTCTCATATCTAACTTCCTCCTTAAAACAGAGAAGGTCAATCTAGTTCCAGAGG
GTTGAGGCAGGTGCCAATAATTACATCTTTGGAGAGGATTTGATTTCTGCCCAGGGATTT
GCTCACCCCAAGGTCATCTGATAATTTCACAGATGCTGTGTAACAGAACACAGCCAAAGT
AAACTGTGTAGGGGAGCCACATTTACATAGGAACCAAATCAATGAATTTAGGGGTTACGA
TTATAGCAATTTAAGGGCCCACCAGAAGCAGGCCTCGAGGAGTCAATTTGCCTCTGTGTG
CCTCAGTGGAGACAAGTGGGAAAACATGGTCCCACCTGTGCGAGACCCCCTGTCCTGTGC
TGCTCACTCAACAACATCTTTGTGTTGCTTTCACCAGGCTGAGACCCTACCCTATGGGGT
ATATGGGCTTTTACCTGTGCACCAGTGTGACAGGAAAGATTCATGTCACTACTGTCCGTG
GCTACAATTCAAAGGTATCCAATGTCGCTGTAAATTTTATGGCACTATTTTTATTGGAGG
ATTTGGTCAGAATGCAGTTGTTGTACAACTCATAAATACTAACTGCTGATTTTGACACAT
GTGTGCTCCAAATGATCTGGTGGTTATTTAACGTACCTCTTAAAATTCGTTGAAACGATT
TCAGGTCAACTCTGAAGAGTATTTGAAAGCAGGACTTCAGAACAGTGTTTGATTTTTATT
TTATAAATTTAAGCATTCAAATTAGGCAAATCTTTGGCTGCAGGCAGCAAAAACAGCTGG
ACTTATTTAAAACAACTTGTTTTTGAGTTTTCTTATATATATATTGATTATTTGTTTTAC
ACACATGCAGTAGCACTTTGGTAAGAGTTAAAGAGTAAAGCAGCTTATGTTGTCAGGTCG
TTCTTATCTAGAGAAGAGCTATAGCAGATCTCGGACAAACTCAGAATATATTCACTTTCA
TTTTTGACAGGATTCCCTCCACAACTCAGTTTCATATATTATTCCGTATTACATTTTTGC
AGCTAAATTACCATAAAATGTCAGCAAATGTAAAAATTTAATTTCTGAAAAGCACCATTA
GCCCATTTCCCCCAAATTAAACGTAAATGTTTTTTTTCAGCACATGTTACCATGTCTGAC
CTGCAAAAATGCTGGAGAAAAATGAAGGAAAAAATTATGTTTTTCAGTTTAATTCTGTTA
ACTGAAGATATTCCAACTCAAAACCAGCCTCATGCTCTGATTAGATAATCTTTTACATTG
AACCTTTACTCTCAAAGCCATGTGTGGAGGGGGCTTGTCACTATTGTAGGCTCACTGGAT
TGGTCATTTAGAGTTTCACAGACTCTTACCAGCATATATAGTATTTAATTGTTTCAAAAA
AAATCAAACTGTAGTTGTTTTGGCGATAGGTCTCACGCAACACATTTTTGTATGTGTGTG
TGTGTGCGTGTGTGTGTGTGTGTGTGAAAAATTGCATTCATTGACTTCAGGTAGATTAAG
GTATCTTTTTATTCATTGCCCTCAGGAAAGTTAAGGTATCAATGAGACCCTTAAGCCAAT
CATGTAATAACTGCATGTGTCTGGTCCAGGAGAAGTATTGAATAAGCCATTTCTACTGCT
TACTCATGTCCCTATTTATGATTTCAACATGGATACATATTTCAGTTCTTTCTTTTTCTC
ACTATCTGAAAATACATTTCCCTCCCTCTCTTCCCCCCAATATCTCCCTTTTTTTCTCTC
TTCCTCTATCTTCCAAACCCCACTTTCTCCCTCCTCCTTTTCCTGTGTTCTCTTAAGCAG
ATAGCACATACCCCCACCCAGTACCAAATTTCAGAACACAAGAAGGTCCAGTTCTTCCCC
CTTCACATAAAGGAACATGGTTTGTCAGCCTTTCTCCTGTTTATGGGTTTCTTCCAGCAG
AACAGAGACATTGCCAACCATATTGGATCTGCTTGCTGTCCAAACCAGCAAACTTTCCTG
GGCAAATCACAATCAGTGAGTAAATAGACAGCCTTTCTGCTGCCTTGGGTTTCTGTGCAG
ATAAACAGAAATGCTCTGATTAGAAAGGAAATGAATGGTTCCACTCAAATGTCCTGCAAT
TTAGGATTGCAGATTTCTGCCTTGAAATACCTGTTTCTTTGGGACATTCCGTCCTGATGA
TTTTTATTTTTGTTGGTTTTTATTTTTGGGGGGAATGACATGTTTGGGTCTTTTATACAT
GAAAATTTGTTTGACAATAATCTCACAAAACATATTTTACATCTGAACAAAATGCCTTTT
TGTTTACCGTAGCGTATACATTTGTTTTGGGATTTTTGTGTGTTTGTTGGGAATTTTGTT
TTTAGCCAGGTCAGTATTGATGAGGCTGATCATTTGGCTCTTTTTTTCCTTCCAGAAGAG
TTGCATCAACAAAGTTAATTGTATTTATGTATGTAAATAGATTTTAAGCTTCATTATAAA
ATATTGTTAATGCCTATAACTTTTTTTCAATTTTTTTGTGTGTGTTTCTAAGGACTTTTT
CTTAGGTTTGCTAAATACTGTAGGGAAAAAAATGCTTCTTTCTACTTTGTTTATTTTAGA
CTTTAAAATGAGCTACTTCTTATTCACTTTTGTAAACAGCTAATAGCATGGTTCCAATTT
TTTTTAAGTTCACTTTTTTTGTTCTAGGGGAAATGAATGTGCAAAAAAAGAAAAAGAACT
GTTGGTTATTTGTGTTATTCTGGATGTATAAAAATCAATGGAAAAAAATAAACTTTCAAA
TTGAAATGACGGTATAACACATCTACTGAAAAAGCAACGGGAAATGTGGTCCTATTTAAG
CCAGCCCCCACCTAGGGTCTATTTGTGTGGCAGTTATTGGGTTTGGTCACAAAACATCCT
GAAAATTCGTGCGTGGGCTTCTTTCTCCCTGGTACAAACGTATGGAATGCTTCTTAAAGG
GGAACTGTCAAGCTGGTGTCTTCAGCCAGATGACATGAGAGAATATCCCAGAACCCTCTC
TCCAAGGTGTTTCTAGATAGCACAGGAGAGCAGGCACTGCACTGTCCACAGTCCACGGTA
CACAGTCGGGTGGGCCGCCTCCCCTCTCCTGGGAGCATTCGTCGTGCCCAGCCTGAGCAG
GGCAGCTGGACTGCTGCTGTTCAGGAGCCACCAGAGCCTTCCTCTCTTTGTACCACAGTT
TCTTCTGTAAATCCAGTGTTACAATCAGTGTGAATGGCAAATAAACAGTTTGACAAGTAC
ATA
3' downstream
caccatatccaattggttttgtctttctctgagatggagggttgggaaactgagtaaggc