BLASTP 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman 
(1997), "Gapped BLAST and PSI-BLAST: a new generation of 
protein database search programs", Nucleic Acids Res. 25:3389-3402.

RID: 1142615206-6003-128897763515.BLASTQ4


Database: Non-redundant SwissProt sequences
           192,555 sequences; 71,789,538 total letters
 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs
Taxonomy reports


Query=  apo2|GENSCAN_predicted_peptide_2|372_aa
Length=372

                                                                   Score     E
Sequences producing significant alignments:                        (Bits)  Value

gi|114006|sp|P06727|APOA4_HUMAN  Apolipoprotein A-IV precursor (A   395    1e-110  
gi|113992|sp|P02647|APOA1_HUMAN  Apolipoprotein A-I precursor ...  77.0    1e-14   
gi|60391728|sp|Q6Q788|APOA5_HUMAN  Apolipoprotein A-V precurso...  70.9    8e-13   
gi|74753569|sp|Q4V328|GRAP1_HUMAN  GRIP1-associated protein 1 (GR  58.2    5e-09   
gi|114039|sp|P02649|APOE_HUMAN  Apolipoprotein E precursor (Apo-E  55.1    4e-08   
gi|8134736|sp|P82094|TMF1_HUMAN  TATA element modulatory factor (  49.7    2e-06   
gi|1730009|sp|P12270|TPR_HUMAN  Nucleoprotein TPR                  49.7    2e-06   
gi|266902|sp|P30622|REST_HUMAN  Restin (Cytoplasmic linker pro...  47.8    7e-06   
gi|1346640|sp|P35580|MYH10_HUMAN  Myosin-10 (Myosin heavy chai...  47.8    7e-06   
gi|71151982|sp|Q7Z406|MYH14_HUMAN  Myosin-14 (Myosin heavy cha...  47.8    7e-06   
gi|6166599|sp|P35579|MYH9_HUMAN  Myosin-9 (Myosin heavy chain,...  47.0    1e-05   
gi|28201804|sp|Q14789|GOGB1_HUMAN  Golgin subfamily B member 1...  45.8    3e-05   
gi|83304912|sp|P12883|MYH7_HUMAN  Myosin heavy chain, cardiac mus  45.8    3e-05 
gi|12643718|sp|Q13439|GOGA4_HUMAN  Golgin subfamily A member 4...  45.8    3e-05   
gi|13432177|sp|P35749|MYH11_HUMAN  Myosin-11 (Myosin heavy chain,  45.1    5e-05   
gi|32470610|sp|Q08378|GOGA3_HUMAN  Golgin subfamily A member 3...  44.3    8e-05   
gi|13638390|sp|P12882|MYH1_HUMAN  Myosin-1 (Myosin heavy chain...  43.9    1e-04   
gi|3043372|sp|P11055|MYH3_HUMAN  Myosin heavy chain, fast skel...  43.9    1e-04   
gi|42558938|sp|Q8TD31|CCHCR_HUMAN  Coiled-coil alpha-helical r...  43.5    1e-04   
gi|3041706|sp|P13533|MYH6_HUMAN  Myosin heavy chain, cardiac musc  43.1    2e-04   
gi|27923755|sp|Q9P2M7|CING_HUMAN  Cingulin                         43.1    2e-04   
gi|13431716|sp|Q9UKX2|MYH2_HUMAN  Myosin heavy chain, skeletal...  42.7    2e-04   
gi|48474907|sp|Q8WYA0|IFT81_HUMAN  Intraflagellar transport 81...  42.7    2e-04   
gi|34222508|sp|Q15075|EEA1_HUMAN  Early endosome antigen 1 (En...  42.4    3e-04   
gi|13431724|sp|Q9Y623|MYH4_HUMAN  Myosin-4 (Myosin heavy chain...  42.4    3e-04   
gi|76803557|sp|P11532|DMD_HUMAN  Dystrophin                        42.0    4e-04 
gi|3041707|sp|P13535|MYH8_HUMAN  Myosin-8 (Myosin heavy chain,...  41.6    5e-04   
gi|50400858|sp|Q14980|NUMA1_HUMAN  Nuclear mitotic apparatus p...  40.4    0.001   
gi|32469733|sp|Q8IWJ2|GCC2_HUMAN  GRIP and coiled-coil domain-...  40.4    0.001   
gi|74739242|sp|Q4ZG46|RBP24_HUMAN  Ran-binding protein 2-like 4 (  40.4    0.001 
gi|13123943|sp|O43707|ACTN4_HUMAN  Alpha-actinin-4 (Non-muscle...  40.0    0.001   
gi|14195007|sp|Q15149|PLEC1_HUMAN  Plectin 1 (PLTN) (PCN) (Hemide  39.7    0.002   
gi|30580364|sp|Q9BV73|CEP2_HUMAN  Centrosomal protein 2 (Centr...  39.7    0.002   
gi|20978868|sp|Q9BY12|ZN291_HUMAN  Zinc finger protein 291         39.7    0.002   
gi|50403702|sp|O95613|PCNT_HUMAN  Pericentrin (Pericentrin B) (Ke  39.7    0.002   
gi|127234|sp|P26038|MOES_HUMAN  Moesin (Membrane-organizing exten  39.3    0.002   
gi|14194461|sp|Q99996|AKAP9_HUMAN  A-kinase anchor protein 9 (...  39.3    0.002   
gi|74713839|sp|Q86SQ7|SDCG8_HUMAN  Serologically defined colon...  39.3    0.002   
gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN  Mitotic spindle assembly ch...  38.9    0.003   
gi|37537846|sp|Q9H8L6|MMRN2_HUMAN  Multimerin-2 precursor (EMI...  38.9    0.003   
gi|30912698|sp|Q8NB25|CF060_HUMAN  Hypothetical protein C6orf60    38.9    0.003   
gi|77416379|sp|Q9UPN4|AZI1_HUMAN  5-azacytidine-induced protei...  38.9    0.003   
gi|1345731|sp|P49454|CENPF_HUMAN  CENP-F kinetochore protein (...  38.5    0.004   
gi|730299|sp|P41219|PERI_HUMAN  Peripherin                         38.5    0.004   
gi|464541|sp|P35241|RADI_HUMAN  Radixin                            38.5    0.004   
gi|27923959|sp|Q03001|BPA1_HUMAN  Bullous pemphigoid antigen 1...  38.5    0.004   
gi|26400672|sp|Q96F44|TRI11_HUMAN  Tripartite motif protein 11...  38.1    0.006   
gi|74759012|sp|Q7L7X3|TAOK1_HUMAN  Serine/threonine-protein ki...  38.1    0.006   
gi|29337005|sp|Q9UQE7|SMC3_HUMAN  Structural maintenance of ch...  38.1    0.006   
gi|13431717|sp|Q9UKX3|MYH13_HUMAN  Myosin-13 (Myosin heavy cha...  38.1    0.006   
gi|32470611|sp|Q08379|GOGA2_HUMAN  Golgin subfamily A member 2...  37.7    0.007   
gi|12643547|sp|O15519|CFLAR_HUMAN  CASP8 and FADD-like apoptos...  37.7    0.007   
gi|78099806|sp|Q9BYV6|TRI55_HUMAN  Tripartite motif-containing...  37.4    0.009 
gi|82581558|sp|Q8TDY2|RBCC1_HUMAN  RB1-inducible coiled-coil prot  37.4    0.009 
gi|62511894|sp|P07196|NFL_HUMAN  Neurofilament triplet L prote...  37.0    0.012   
gi|41688595|sp|Q9UJC3|HOOK1_HUMAN  Hook homolog 1 (h-hook1) (hHK1  37.0    0.012   
gi|29336622|sp|Q14683|SMC1A_HUMAN  Structural maintenance of c...  37.0    0.012   
gi|2501084|sp|Q16623|STX1A_HUMAN  Syntaxin-1A (Neuron-specific an  37.0    0.012   
gi|78099183|sp|Q9H2K8|TAOK3_HUMAN  Serine/threonine-protein ki...  36.6    0.016   
gi|74762299|sp|Q6DT37|MRCKG_HUMAN  Serine/threonine-protein ki...  36.6    0.016   
gi|34098465|sp|Q86UP2|KTN1_HUMAN  Kinectin (Kinesin receptor) (CG  36.6    0.016   
gi|74746874|sp|Q5VT25|MRCKA_HUMAN  Serine/threonine-protein ki...  36.6    0.016   
gi|50401600|sp|Q8N0X7|SPG20_HUMAN  Spartin (Trans-activated by he  36.2    0.021   
gi|47117086|sp|P61266|STX1C_HUMAN  Syntaxin-1B2                    36.2    0.021   
gi|23831094|sp|O00291|HIP1_HUMAN  Huntingtin-interacting protein   36.2    0.021   
gi|74762068|sp|Q9Y5S2|MRCKB_HUMAN  Serine/threonine-protein ki...  35.8    0.028   
gi|2506805|sp|P24043|LAMA2_HUMAN  Laminin alpha-2 chain precur...  35.8    0.028   
gi|33301318|sp|Q92614|MY18A_HUMAN  Myosin-18A (Myosin XVIIIa) ...  35.4    0.036   
gi|48474780|sp|P78386|KRHB5_HUMAN  Keratin, type II cuticular Hb5  35.4    0.036   
gi|13431563|sp|O75146|HIP1R_HUMAN  Huntingtin-interacting prot...  35.4    0.036   
gi|2501085|sp|Q15531|STX1B_HUMAN  Syntaxin-1B1 (Syntaxin 1B)       35.4    0.036   
gi|51701377|sp|O15083|ERC2_HUMAN  ERC protein 2                    35.4    0.036   
gi|41688592|sp|Q96ED9|HOOK2_HUMAN  Hook homolog 2 (h-hook2) (hHK2  35.4    0.036   
gi|17368936|sp|Q9H169|STMN4_HUMAN  Stathmin-4 (Stathmin-like prot  35.0    0.047   
gi|547750|sp|P35900|K1C20_HUMAN  Keratin, type I cytoskeletal ...  35.0    0.047   
gi|3024609|sp|Q15431|SYCP1_HUMAN  Synaptonemal complex protein 1   35.0    0.047   
gi|74736716|sp|Q6NSJ2|PHLB3_HUMAN  Hypothetical pleckstrin homolo  35.0    0.047   
gi|51827892|sp|Q8IUD2|RB6I2_HUMAN  RAB6-interacting protein 2 (ER  34.7    0.061   
gi|547749|sp|P13645|K1C10_HUMAN  Keratin, type I cytoskeletal ...  34.7    0.061   
gi|26006960|sp|O75955|FLOT1_HUMAN  Flotillin-1                     34.3    0.080   
gi|125081|sp|P19012|K1C15_HUMAN  Keratin, type I cytoskeletal ...  34.3    0.080   
gi|26392576|sp|Q9NUD7|CT096_HUMAN  Protein C20orf96                34.3    0.080   
gi|32699565|sp|Q8IUG5|MY18B_HUMAN  Myosin-18B (Myosin XVIIIb)      34.3    0.080   
gi|13124319|sp|O60282|KIF5C_HUMAN  Kinesin heavy chain isoform...  33.9    0.10    
gi|46397807|sp|O76014|K1H7_HUMAN  Keratin, type I cuticular Ha7 (  33.9    0.10    
gi|23822112|sp|Q9P2E9|RRBP1_HUMAN  Ribosome-binding protein 1 ...  33.5    0.14    
gi|48474671|sp|Q9NSB2|KRHB4_HUMAN  Keratin, type II cuticular Hb4  33.5    0.14    
gi|399227|sp|Q02224|CENPE_HUMAN  Centromeric protein E (CENP-E pr  33.5    0.14    
gi|6685537|sp|Q14152|IF3A_HUMAN  Eukaryotic translation initia...  33.5    0.14    
gi|543742|sp|P35609|ACTN2_HUMAN  Alpha-actinin-2 (Alpha actini...  33.5    0.14    
gi|417216|sp|P33176|KINH_HUMAN  Kinesin heavy chain (Ubiquitous k  33.5    0.14    
gi|29839561|sp|Q8NF91|SYNE1_HUMAN  Nesprin-1 (Nuclear envelope...  33.5    0.14    
gi|2498281|sp|Q16204|CCDC6_HUMAN  Coiled-coil domain-containin...  33.1    0.18    
gi|51704330|sp|Q93045|STMN2_HUMAN  Stathmin-2 (SCG10 protein) ...  33.1    0.18    
gi|47117845|sp|P32856|STX2_HUMAN  Epimorphin (Syntaxin-2)          33.1    0.18    
gi|126366|sp|P07942|LAMB1_HUMAN  Laminin beta-1 chain precursor (  33.1    0.18    
gi|1174915|sp|P46939|UTRO_HUMAN  Utrophin (Dystrophin-related pro  33.1    0.18    
gi|400793|sp|Q00722|PLCB2_HUMAN  1-phosphatidylinositol-4,5-bi...  33.1    0.18    
gi|34925430|sp|Q9HCN4|XAB1_HUMAN  XPA-binding protein 1            33.1    0.18    
gi|62287118|sp|Q96CV9|OPTN_HUMAN  Optineurin (Optic neuropathy...  33.1    0.18    
gi|37537841|sp|Q9BXX0|EMIL2_HUMAN  EMILIN-2 precursor (Elastin...  33.1    0.18    
gi|74749713|sp|Q6ZWJ1|STXB4_HUMAN  Syntaxin-binding protein 4 ...  32.7    0.23    
gi|20138710|sp|Q9BW19|KIFC1_HUMAN  Kinesin-like protein KIFC1 ...  32.7    0.23    
gi|128147|sp|P07197|NFM_HUMAN  Neurofilament triplet M protein...  32.7    0.23    
gi|13431284|sp|Q9UPM8|AP4E1_HUMAN  AP-4 complex subunit epsilo...  32.7    0.23    
gi|56405385|sp|Q9HCM9|TRI39_HUMAN  Tripartite motif protein 39...  32.3    0.30    
gi|46396501|sp|Q9BRK4|LZTS2_HUMAN  Leucine zipper putative tumor   32.3    0.30    
gi|20137431|sp|Q99941|ATF6B_HUMAN  Cyclic AMP-dependent transc...  32.3    0.30    
gi|74732524|sp|Q96NA2|RILP_HUMAN  Rab-interacting lysosomal prote  32.3    0.30    
gi|2497600|sp|Q13751|LAMB3_HUMAN  Laminin beta-3 chain precurs...  32.3    0.30    
gi|134973|sp|P16949|STMN1_HUMAN  Stathmin (Phosphoprotein p19)...  32.3    0.30    
gi|12643814|sp|Q9NQ66|PLCB1_HUMAN  1-phosphatidylinositol-4,5-...  32.3    0.30    
gi|12230855|sp|Q99543|ZRF1_HUMAN  Zuotin-related factor 1 (M-phas  32.3    0.30    
gi|62511032|sp|Q6UVJ0|SAS6_HUMAN  Spindle assembly abnormal prote  32.0    0.40    
gi|10720353|sp|O15078|CE290_HUMAN  Centrosomal protein Cep290      32.0    0.40    
gi|48428272|sp|Q9UIF7|MUTYH_HUMAN  A/G-specific adenine DNA glyco  31.6    0.52    
gi|71153185|sp|Q9UPW8|UN13A_HUMAN  Unc-13 homolog A (Munc13-1)     31.6    0.52  
gi|25090171|sp|Q8TEK3|DOT1L_HUMAN  Histone-lysine N-methyltran...  31.6    0.52    
gi|23396625|sp|Q9NQT8|KI13B_HUMAN  Kinesin-like protein KIF13B (K  31.2    0.68    
gi|23503075|sp|P08779|K1C16_HUMAN  Keratin, type I cytoskeleta...  31.2    0.68    
gi|6016414|sp|Q14532|K1H2_HUMAN  Keratin, type I cuticular Ha2 (H  31.2    0.68    
gi|48475013|sp|Q9UMX0|UBQL1_HUMAN  Ubiquilin-1 (Protein linkin...  31.2    0.68    
gi|50403793|sp|Q96L93|SNX23_HUMAN  Kinesin-like motor protein C20  31.2    0.68    
gi|13431713|sp|Q9NQX4|MYO5C_HUMAN  Myosin-5C (Myosin Vc)           31.2    0.68    
gi|29427585|sp|O95819|M4K4_HUMAN  Mitogen-activated protein ki...  31.2    0.68    
gi|71153214|sp|Q68D86|CR014_HUMAN  Hypothetical protein C18orf14   31.2    0.68    
gi|6175045|sp|Q13277|STX3_HUMAN  Syntaxin-3                        31.2    0.68    
gi|38605459|sp|Q9C035|TRIM5_HUMAN  Tripartite motif protein 5 (RI  30.8    0.89    
gi|13959419|sp|Q9UJF2|NGAP_HUMAN  Ras GTPase-activating protei...  30.8    0.89    
gi|47606049|sp|Q9H5N1|RABE2_HUMAN  Rab GTPase-binding effector pr  30.8    0.89    
gi|22096362|sp|P54252|ATX3_HUMAN  Ataxin-3 (Machado-Joseph dis...  30.8    0.89    
gi|34098604|sp|Q8TD16|BICD2_HUMAN  Cytoskeleton-like bicaudal D p  30.4    1.2     
gi|20455324|sp|Q9H2D6|TARA_HUMAN  TRIO and F-actin binding pro...  30.4    1.2     
gi|41688524|sp|Q9UMD9|COHA1_HUMAN  Collagen alpha-1(XVII) chai...  30.4    1.2     
gi|20455319|sp|Q92994|TF3B_HUMAN  Transcription factor IIIB 90...  30.4    1.2     
gi|134461|sp|P05060|SCG1_HUMAN  Secretogranin-1 precursor (Sec...  30.4    1.2     
gi|50400772|sp|Q8N4C6|NIN_HUMAN  Ninein (hNinein)                  30.4    1.2     
gi|30316105|sp|Q96PK2|MACF4_HUMAN  Microtubule-actin crosslinking  30.4    1.2     
gi|68566185|sp|Q6PKC3|TXD11_HUMAN  Thioredoxin domain-containi...  30.4    1.2     
gi|73620945|sp|O94833|BPAEA_HUMAN  Bullous pemphigoid antigen ...  30.4    1.2   
gi|74753268|sp|Q9UDT6|CYLN2_HUMAN  Cytoplasmic linker protein ...  30.0    1.5     
gi|2501092|sp|Q13190|STX5_HUMAN  Syntaxin-5                        30.0    1.5     
gi|61247587|sp|Q969G3|SMCE1_HUMAN  SWI/SNF-related matrix-asso...  30.0    1.5     
gi|123408|sp|P28069|PIT1_HUMAN  Pituitary-specific positive tr...  30.0    1.5     
gi|68846601|sp|O60664|M6PBP_HUMAN  Mannose-6-phosphate recepto...  30.0    1.5   
gi|42560524|sp|O60333|KIF1B_HUMAN  Kinesin-like protein KIF1B (Kl  30.0    1.5     
gi|134798|sp|P11277|SPTB1_HUMAN  Spectrin beta chain, erythrocyte  29.6    2.0     
gi|32699595|sp|Q96CN9|GCC1_HUMAN  GRIP and coiled-coil domain-...  29.6    2.0     
gi|586120|sp|Q07283|TRHY_HUMAN  Trichohyalin                       29.6    2.0     
gi|126369|sp|P11047|LAMC1_HUMAN  Laminin gamma-1 chain precursor   29.6    2.0     
gi|125953|sp|P20700|LMNB1_HUMAN  Lamin-B1                          29.6    2.0     
gi|122824|sp|P13196|HEM1_HUMAN  5-aminolevulinate synthase, no...  29.6    2.0     
gi|71152997|sp|Q7Z3E2|CJ118_HUMAN  Protein C10orf118 (CTCL tumor   29.6    2.0     
gi|48474260|sp|O43790|KRHB6_HUMAN  Keratin, type II cuticular ...  29.6    2.0     
gi|47606192|sp|Q8WV44|TRI41_HUMAN  Tripartite motif protein 41     29.6    2.0     
gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN  Myosin-5A (Myosin Va) (Dilu...  29.6    2.0     
gi|33112673|sp|Q9Y496|KIF3A_HUMAN  Kinesin-like protein KIF3A ...  29.6    2.0     
gi|51701437|sp|Q8TF61|FBX41_HUMAN  F-box only protein 41           29.6    2.0     
gi|129886|sp|P16112|PGCA_HUMAN  Aggrecan core protein precurso...  29.6    2.0     
gi|20532393|sp|O15230|LAMA5_HUMAN  Laminin alpha-5 chain precurso  29.6    2.0     
gi|37999758|sp|Q96PP9|GBP4_HUMAN  Guanylate binding protein 4      29.3    2.6   
gi|3183210|sp|Q15027|CENB1_HUMAN  Centaurin-beta 1 (Cnt-b1)        29.3    2.6     
gi|2498733|sp|Q14444|GP137_HUMAN  GPI-anchored protein p137 (p...  29.3    2.6     
gi|46397468|sp|Q14533|KRHB1_HUMAN  Keratin, type II cuticular ...  29.3    2.6     
gi|6136547|sp|O60299|Y0552_HUMAN  Hypothetical protein KIAA0552    28.9    3.4     
gi|34223086|sp|Q9UKI8|TLK1_HUMAN  Serine/threonine-protein kin...  28.9    3.4     
gi|41702296|sp|Q8NI27|THOC2_HUMAN  THO complex subunit 2 (Tho2)    28.9    3.4     
gi|2497523|sp|Q12756|KIF1A_HUMAN  Kinesin-like protein KIF1A (...  28.9    3.4     
gi|3913961|sp|O43896|KIF1C_HUMAN  Kinesin-like protein KIF1C       28.9    3.4     
gi|25014073|sp|O43615|TIM44_HUMAN  Import inner membrane trans...  28.9    3.4     
gi|84027768|sp|O75150|BRE1B_HUMAN  Ubiquitin ligase protein BR...  28.9    3.4   
gi|1171955|sp|P42338|PK3CB_HUMAN  Phosphatidylinositol-4,5-bis...  28.9    3.4     
gi|47605777|sp|O95140|MFN2_HUMAN  Transmembrane GTPase MFN2 (Mito  28.9    3.4     
gi|25452905|sp|Q9H501|CT006_HUMAN  Hypothetical protein C20orf6    28.9    3.4     
gi|134517|sp|P12755|SKI_HUMAN  Ski oncogene (C-ski)                28.9    3.4     
gi|56417894|sp|Q8NE71|ABCF1_HUMAN  ATP-binding cassette sub-fa...  28.9    3.4     
gi|52783461|sp|Q8NEE8|TTC16_HUMAN  Tetratricopeptide repeat prote  28.9    3.4     
gi|88909227|sp|Q6WCQ1|MRIP_HUMAN  Myosin phosphatase Rho-inter...  28.9    3.4   
gi|125962|sp|P02545|LMNA_HUMAN  Lamin-A/C (70 kDa lamin)           28.5    4.4     
gi|20138952|sp|Q15025|NAF1_HUMAN  Nef-associated factor 1 (Naf...  28.5    4.4     
gi|13124704|sp|Q14457|BCN1_HUMAN  Beclin-1 (Coiled-coil myosin...  28.5    4.4     
gi|33302627|sp|Q15643|TRIPB_HUMAN  Thyroid receptor-interactin...  28.5    4.4     
gi|30173225|sp|O95347|SMC2_HUMAN  Structural maintenance of ch...  28.5    4.4     
gi|62511890|sp|Q6UWE0|LRSM1_HUMAN  Ubiquitin ligase protein LR...  28.1    5.7     
gi|48474320|sp|P78385|KRHB3_HUMAN  Keratin, type II cuticular Hb3  28.1    5.7     
gi|71658803|sp|Q6TFL3|CI093_HUMAN  Protein C9orf93                 28.1    5.7     
gi|56405102|sp|Q9UJ41|RABX5_HUMAN  Rab5 GDP/GTP exchange factor (  28.1    5.7     
gi|34978376|sp|Q9P2E2|KIF17_HUMAN  Kinesin-like protein KIF17 (KI  28.1    5.7     
gi|13124096|sp|Q9ULW0|TPX2_HUMAN  Targeting protein for Xklp2 ...  27.7    7.5     
gi|25009488|sp|Q9C030|TRIM6_HUMAN  Tripartite motif protein 6 (RI  27.7    7.5     
gi|14424221|sp|O75154|RFIP3_HUMAN  Rab11 family-interacting pr...  27.7    7.5     
gi|56749614|sp|Q6NZI2|PTRF_HUMAN  Polymerase I and transcript rel  27.7    7.5     
gi|21264472|sp|P37198|NUP62_HUMAN  Nuclear pore glycoprotein p62   27.7    7.5     
gi|12644130|sp|P15924|DESP_HUMAN  Desmoplakin (DP) (250/210 kDa p  27.7    7.5     
gi|41688815|sp|Q9NQZ6|HC127_HUMAN  Hepatocellular carcinoma-assoc  27.7    7.5     
gi|62899891|sp|Q9HC77|CENPJ_HUMAN  Centromere protein J (Centr...  27.7    7.5     
gi|47116932|sp|Q9NQ29|LUC7L_HUMAN  Putative RNA-binding protei...  27.7    7.5     
gi|29427676|sp|Q16891|IMMT_HUMAN  Mitochondrial inner membrane...  27.7    7.5     
gi|13432173|sp|P02533|K1C14_HUMAN  Keratin, type I cytoskeleta...  27.7    7.5     
gi|57013034|sp|O95425|SVIL_HUMAN  Supervillin (Archvillin) (p205/  27.7    7.5     
gi|57015308|sp|Q14204|DYHC_HUMAN  Dynein heavy chain, cytosoli...  27.7    7.5     
gi|62510844|sp|O95202|LETM1_HUMAN  Leucine zipper-EF-hand cont...  27.7    7.5     
gi|2492629|sp|Q14957|NMDE3_HUMAN  Glutamate [NMDA] receptor su...  27.7    7.5     
gi|81175034|sp|Q9BYV2|TRI54_HUMAN  Tripartite motif protein 54...  27.7    7.5     
gi|37999757|sp|Q96PP8|GBP5_HUMAN  Interferon-induced guanylate...  27.3    9.8     
gi|74760765|sp|Q96CN5|LRC45_HUMAN  Leucine-rich repeat-containing  27.3    9.8     
gi|7387887|sp|O00566|MPP10_HUMAN  U3 small nucleolar ribonucle...  27.3    9.8     
gi|21759268|sp|Q9Y5Q3|MAFB_HUMAN  Transcription factor MafB (V...  27.3    9.8     
gi|34098767|sp|Q9Y4D1|DAAM1_HUMAN  Disheveled-associated activato  27.3    9.8     
gi|14424230|sp|Q9Y2G4|ANKR6_HUMAN  Ankyrin repeat domain protein   27.3    9.8     
gi|82654947|sp|P19013|K2C4_HUMAN  Keratin, type II cytoskeleta...  27.3    9.8   
gi|120487|sp|P15408|FOSL2_HUMAN  Fos-related antigen 2             27.3    9.8     
gi|20139068|sp|Q96PB7|NOE3_HUMAN  Noelin-3 precursor (Olfactomedi  27.3    9.8     
gi|45644957|sp|P25067|CO8A2_HUMAN  Collagen alpha-2(VIII) chain p  27.3    9.8     
gi|6647481|sp|O14576|DYI1_HUMAN  Dynein intermediate chain 1, ...  27.3    9.8     
gi|23396623|sp|Q9H1H9|KI13A_HUMAN  Kinesin-like protein KIF13A (K  27.3    9.8     
gi|2497603|sp|Q13753|LAMC2_HUMAN  Laminin gamma-2 chain precur...  27.3    9.8     

Alignments

>gi|114006|sp|P06727|APOA4_HUMAN  Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV)
Length=396

 Score =  395 bits (1016),  Expect = 1e-110
 Identities = 206/235 (87%), Positives = 216/235 (91%), Gaps = 9/235 (3%)

Query  37   QLSNNAKEAVEHLQK--SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL  94
            ++ +N +E  + L+    +L  Q+N        +AEQLRRQLTPYAQRMERVLRENADSL
Sbjct  123  KIGDNLRELQQRLEPYADQLRTQVNT-------QAEQLRRQLTPYAQRMERVLRENADSL  175

Query  95   QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
            QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN
Sbjct  176  QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  235

Query  155  HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
            HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL+GNTEGLQKSLAELGGH
Sbjct  236  HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLKGNTEGLQKSLAELGGH  295

Query  215  LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
            LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK
Sbjct  296  LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  350


 Score = 44.3 bits (103),  Expect = 8e-05
 Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 9/140 (6%)

Query  23   SADQVATVMWDYFSQLSNNAKEAVEHLQKS--ELTQQLNALFQDKLGEAEQLRRQLTPYA  80
            SA+++   +      +  N K   E LQKS  EL   L+        + E+ RR++ PY 
Sbjct  259  SAEELRQRLAPLAEDVRGNLKGNTEGLQKSLAELGGHLDQ-------QVEEFRRRVEPYG  311

Query  81   QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
            +   + L +  + L+  L PHA +++  +    ++L+ ++  +   FK K  Q       
Sbjct  312  ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLP  371

Query  141  SLAPYAQDTQEKLNHQLEGL  160
             L    +  QE+   Q++ L
Sbjct  372  ELEQQQEQQQEQQQEQVQML  391


>gi|113992|sp|P02647|APOA1_HUMAN  Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) [Contains: Apolipoprotein 
A-I(1-242)]
Length=267

 Score = 77.0 bits (188),  Expect = 1e-14
 Identities = 54/229 (23%), Positives = 103/229 (44%), Gaps = 19/229 (8%)

Query  25   DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEA----EQLRRQLTPYA  80
            D+V  +   Y   L ++ ++ V   + S L +QLN    D          +LR QL P  
Sbjct  33   DRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVT  92

Query  81   QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
            Q               +L    + L+ ++ +++EE+K ++ PY D+F+ K  + +E  R+
Sbjct  93   QEF-----------WDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ  141

Query  141  SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN  200
             + P   + QE    +L  L  ++    EE++ R  A  + LR  LAP ++++R  L   
Sbjct  142  KVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAAR  201

Query  201  TEGLQKS----LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR  245
             E L+++    LAE      + +     + +P  E+  + L+  +E  +
Sbjct  202  LEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFK  250


 Score = 58.9 bits (141),  Expect = 3e-09
 Identities = 41/191 (21%), Positives = 86/191 (45%), Gaps = 14/191 (7%)

Query  32   WDYFSQLSNNAKEAVEHLQKS---ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLR  88
            WD  +   +  +E +  + +     L ++   L Q+   + E+++ ++ PY    ++  +
Sbjct  74   WDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQ  133

Query  89   ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD  148
            E  +  +  + P   EL+    Q + EL+ +L+P  +E + +    V+ LR  LAPY+ +
Sbjct  134  EEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDE  193

Query  149  TQEKLNHQLEGLT-----------FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL  197
             +++L  +LE L             +  ++   L  +   + E+LRQ L P+ E  + + 
Sbjct  194  LRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSF  253

Query  198  RGNTEGLQKSL  208
                E   K L
Sbjct  254  LSALEEYTKKL  264


 Score = 54.7 bits (130),  Expect = 6e-08
 Identities = 36/147 (24%), Positives = 70/147 (47%), Gaps = 8/147 (5%)

Query  131  IDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLA  190
            +  T  +LR  L P  Q+  + L  + EGL  +M K+ EE+KA++    ++ +++     
Sbjct  77   VTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEM  136

Query  191  EDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP  250
            E  R       + ++   AEL     Q++ E + ++ P GE         ++ LR  L P
Sbjct  137  ELYR-------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAP  189

Query  251  HAGDVEGHLSFLEKDLRDKNWGLRLGD  277
            ++ ++   L+   + L++ N G RL +
Sbjct  190  YSDELRQRLAARLEALKE-NGGARLAE  215


 Score = 50.1 bits (118),  Expect = 1e-06
 Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 9/124 (7%)

Query  135  VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAED  192
            V++L        +D+      Q EG     + N + L     ++++  +LR++L P+ ++
Sbjct  35   VKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQE  94

Query  193  VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA  252
               NL   TEGL++ +++        +EE + +V+PY ++F K   ++ME  RQK+ P  
Sbjct  95   FWDNLEKETEGLRQEMSK-------DLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLR  147

Query  253  GDVE  256
             +++
Sbjct  148  AELQ  151


 Score = 45.1 bits (105),  Expect = 5e-05
 Identities = 37/154 (24%), Positives = 67/154 (43%), Gaps = 5/154 (3%)

Query  25   DQVATVMWDYFSQLSNNAKEAVE-HLQKSE-LTQQLNALFQDKLGEAEQLRRQLTPYAQR  82
            ++V   +  Y        +E +E + QK E L  +L    + KL E   L+ +L+P  + 
Sbjct  115  EEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHE---LQEKLSPLGEE  171

Query  83   MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
            M    R + D+L+  L P++DEL+ ++   +E LK        E+  K  + +  L    
Sbjct  172  MRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKA  231

Query  143  APYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS  176
             P  +D ++ L   LE          EE   +++
Sbjct  232  KPALEDLRQGLLPVLESFKVSFLSALEEYTKKLN  265


>gi|60391728|sp|Q6Q788|APOA5_HUMAN  Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) 
(Regeneration-associated protein 3)
Length=366

 Score = 70.9 bits (172),  Expect = 8e-13
 Identities = 75/315 (23%), Positives = 126/315 (40%), Gaps = 85/315 (26%)

Query  23   SADQVATVMWDYFSQLSNNAKEAVEHLQ-----------KSELTQQLN------------  59
            SA Q     WDYFSQ S + K  VE +            K  L Q LN            
Sbjct  19   SATQARKGFWDYFSQTSGD-KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPL  77

Query  60   ------ALFQDKLG-------EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
                   L QD +G       E E+++ +L PY      ++  N + L+  L+P+  +L 
Sbjct  78   SGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLM  137

Query  107  AKIDQNVEELKGRLT----------------------------------------PYADE  126
             ++   V+EL+ +L                                         PYA+ 
Sbjct  138  EQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAES  197

Query  127  FKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL  186
                I + V+EL RS+AP+A  +  +L+  ++ L+ ++   A+ L ARI  + ++LR+ L
Sbjct  198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL  257

Query  187  APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ  246
            +           G  EG       L   + Q+++ FR+        F +A+ Q+ E+++Q
Sbjct  258  SRAFAGT-----GTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQ  312

Query  247  KLGPHAGDVEGHLSF  261
            +L P      GH +F
Sbjct  313  QLAP---PPPGHSAF  324


 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 12/122 (9%)

Query  184  QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
            ++L PL+      L  +  G+++ L E       ++EE + R++PY    ++ +   +E 
Sbjct  72   EKLRPLSGSEAPRLPQDPVGMRRQLQE-------ELEEVKARLQPYMAEAHELVGWNLEG  124

Query  244  LRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGE--EGQSRGMQALQGFPGRGL  301
            LRQ+L P+  D+   ++   ++L+++   LR+   D   +   G       LQG   R +
Sbjct  125  LRQQLKPYTMDLMEQVALRVQELQEQ---LRVVGEDTKAQLLGGVDEAWALLQGLQSRVV  181

Query  302  EH  303
             H
Sbjct  182  HH  183


>gi|74753569|sp|Q4V328|GRAP1_HUMAN  GRIP1-associated protein 1 (GRASP-1)
Length=841

 Score = 58.2 bits (139),  Expect = 5e-09
 Identities = 65/237 (27%), Positives = 114/237 (48%), Gaps = 21/237 (8%)

Query  45   AVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE  104
            A+E +Q ++ TQ+LN L +   G A +L++Q   Y   M +    N+  LQ SLR ++  
Sbjct  344  ALEQIQTAK-TQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDLNSQ-LQESLRANSRL  401

Query  105  LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDT-QEKLNH--QLEGLT  161
            L+    Q + + K +LT    E +    ++ E+ +  L   A +T QEK  H  +L  + 
Sbjct  402  LEQL--QEIGQEKEQLTQELQEAR----KSAEKRKAMLDELAMETLQEKSQHKEELGAVR  455

Query  162  FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNT------EGLQKSLAELGGH-  214
             + +K    ++AR      EL +      E++RG +R         E LQ+++ EL    
Sbjct  456  LRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQV  515

Query  215  --LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
              +D     F RR++   E+  +   +Q E L+Q    HA +++G    L+ D+RD+
Sbjct  516  HSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQ-DVRDQ  571


 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 29/149 (19%)

Query  51   KSELTQQLNALFQDKLGEAEQLRRQLTPYAQR---------------------------M  83
            ++   ++L  L +DK  + E+LR Q+     R                            
Sbjct  466  RARYERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWF  525

Query  84   ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA  143
            ER L+E  +SLQ   +   + LK   +Q+  ELKG+     D  + +++Q  EE    L 
Sbjct  526  ERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKEEELQD-VRDQLEQAQEERDCHLK  584

Query  144  PYAQDTQEKLNHQLEGLTFQMKKNAEELK  172
              +   QE +   ++G     KK +  LK
Sbjct  585  TISSLKQE-VKDTVDGQRILEKKGSAALK  612


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 28/136 (20%), Positives = 67/136 (49%), Gaps = 10/136 (7%)

Query  46   VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL  105
            +E LQ++   ++L A      G      R+L    + +++  +E  ++L+     HA EL
Sbjct  501  LETLQQT--VEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAEL  558

Query  106  KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD---TQEKLNHQLEGLTF  162
            K K ++ +++++ +L    +E    + +T+  L++ +          ++K +  L+ L  
Sbjct  559  KGK-EEELQDVRDQLEQAQEERDCHL-KTISSLKQEVKDTVDGQRILEKKGSAALKDLKR  616

Query  163  QM---KKNAEELKARI  175
            Q+   +K A++L+ R+
Sbjct  617  QLHLERKRADKLQERL  632


>gi|114039|sp|P02649|APOE_HUMAN  Apolipoprotein E precursor (Apo-E)
Length=317

 Score = 55.1 bits (131),  Expect = 4e-08
 Identities = 65/268 (24%), Positives = 109/268 (40%), Gaps = 34/268 (12%)

Query  28   ATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVL  87
            A ++  + +      ++AVE   + EL QQ       +   A         + Q +   +
Sbjct  6    AALLVTFLAGCQAKVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQV  65

Query  88   RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ  147
            +E   S Q +      EL+A +D+ ++ELK     Y  E + ++    EE R  L+   Q
Sbjct  66   QEELLSSQVT-----QELRALMDETMKELKA----YKSELEEQLTPVAEETRARLSKELQ  116

Query  148  DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS  207
              Q +L   +E +  ++ +   E++A +  S EELR RLA     +R  L  + + LQK 
Sbjct  117  AAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKR  176

Query  208  LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP--HAGDVE----GHLSF  261
            LA                   Y     +   + +  +R++LGP    G V     G L+ 
Sbjct  177  LA------------------VYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAG  218

Query  262  LEKDLRDKNWGLRLGDR-DESGEEGQSR  288
                 R + WG RL  R +E G   + R
Sbjct  219  QPLQERAQAWGERLRARMEEMGSRTRDR  246


 Score = 45.1 bits (105),  Expect = 5e-05
 Identities = 37/162 (22%), Positives = 77/162 (47%), Gaps = 4/162 (2%)

Query  63   QDKLGEA-EQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLT  121
            Q  LG++ E+LR +L  + +++ + L  +AD LQ  L  +    +   ++ +  ++ RL 
Sbjct  141  QAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLG  200

Query  122  PYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK---ARISAS  178
            P  ++ +V+         + L   AQ   E+L  ++E +  + +   +E+K   A + A 
Sbjct  201  PLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAK  260

Query  179  AEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE  220
             EE  Q++   AE  +  L+   E L + +      L ++V+
Sbjct  261  LEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQ  302


>gi|8134736|sp|P82094|TMF1_HUMAN  TATA element modulatory factor (TMF)
Length=1093

 Score = 49.7 bits (117),  Expect = 2e-06
 Identities = 57/249 (22%), Positives = 110/249 (44%), Gaps = 25/249 (10%)

Query  38   LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            +    K + + L  S + ++L A  ++      +L +++    + ++  L++  D  +  
Sbjct  559  MEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQH-LKQVLDGKEEV  617

Query  98   LRPHADELKAKIDQNVEELK---GRLTPYADEFKVK---IDQTVEELRRSLAPYAQDTQE  151
             + H + +K K++  VE  +   GRL    DE + K   I   ++   + L    +    
Sbjct  618  EKQHRENIK-KLNSMVERQEKDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAA  676

Query  152  KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
            K +   E    +  K  EEL A +  + EE RQ+   LA  V G+LR   +  +++ A  
Sbjct  677  KDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQV-GDLRLALQRTEQAAARK  735

Query  212  GGHLDQQVEEFRRRVEPYGENFN-----------KALVQQMEQLRQKLGPHAGDVEGHLS  260
              +L  ++ E ++R++   EN N           + L++Q+E L+  LG      E    
Sbjct  736  EDYLRHEIGELQQRLQE-AENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWEK---  791

Query  261  FLEKDLRDK  269
             LEK+L D+
Sbjct  792  -LEKNLSDR  799


 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 45/193 (23%), Positives = 85/193 (44%), Gaps = 28/193 (14%)

Query  63   QDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTP  122
            Q +L EAE   ++L+       R L    ++LQA+L       + K+++N+ +  G    
Sbjct  747  QQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWE-KLEKNLSDRLG----  801

Query  123  YADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN-AEELKARISASAEE  181
               E +  +   VE  R +       T+E L ++++  + + + +   +  +R  A  E 
Sbjct  802  ---ESQTLLAAAVERERAA-------TEELLANKIQMSSMESQNSLLRQENSRFQAQLES  851

Query  182  LRQRLAPLAEDVRGNLRGNTEGLQ----KSLAELGGH---LDQQVEEFRRRVEPYGENFN  234
             + RL  L ED     +   E L+    ++L E       L+ Q+E  R +VE   +   
Sbjct  852  EKNRLCKL-EDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVE---QERK  907

Query  235  KALVQQMEQLRQK  247
            KA+  Q E +++K
Sbjct  908  KAIFTQ-ETIKEK  919


>gi|1730009|sp|P12270|TPR_HUMAN  Nucleoprotein TPR
Length=2349

 Score = 49.7 bits (117),  Expect = 2e-06
 Identities = 57/241 (23%), Positives = 110/241 (45%), Gaps = 23/241 (9%)

Query  50    QKSELTQQLNALF---QDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             +K  + + L+A     Q+K+    Q+++    Y  + E +  +    ++ S +   D  +
Sbjct  1409  EKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQE  1468

Query  107   AKID-QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK  165
               +  Q ++ELK  L     + K  ++  VE L+++L+    + +  L  Q   L  ++ 
Sbjct  1469  QHVSVQEMQELKETLNQAETKSK-SLESQVENLQKTLSEKETEARN-LQEQTVQLQSELS  1526

Query  166   KNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ---QVEEF  222
             +  ++L+ R +   E+LRQ++    E  R  +       +  +A L G  DQ   + EE 
Sbjct  1527  RLRQDLQDR-TTQEEQLRQQITEKEEKTRKAI----VAAKSKIAHLAGVKDQLTKENEEL  1581

Query  223   RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESG  282
             ++R        N AL QQ ++L  ++       EG +S LE++LR+ +    L  RDE  
Sbjct  1582  KQR--------NGALDQQKDELDVRITALKSQYEGRISRLERELRE-HQERHLEQRDEPQ  1632

Query  283   E  283
             E
Sbjct  1633  E  1633


 Score = 44.3 bits (103),  Expect = 8e-05
 Identities = 52/230 (22%), Positives = 100/230 (43%), Gaps = 22/230 (9%)

Query  33    DYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
             D  + L  N KE +++ QK     ++  L Q       Q+  Q +    + +   +E+ D
Sbjct  881   DTETNLHLNTKELLKNAQK-----EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVD  935

Query  93    SLQASLRP---HADELKAKID---QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYA  146
              L + LR      ++LK ++     NVE+ +  +T   +    K  Q  EE+R+++    
Sbjct  936   DLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-KEKQVTEEVRKNIEVRL  994

Query  147   QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK  206
             +++ E    QLE    +++K  +EL+     + E + Q+L+ L + +        E LQ+
Sbjct  995   KESAE-FQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQR  1053

Query  207   SLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE  256
             +   L        ++ RR  +       K  V+   +  ++L  HA DVE
Sbjct  1054  ASTALSNE-----QQARRDCQEQA----KIAVEAQNKYERELMLHAADVE  1094


 Score = 37.0 bits (84),  Expect = 0.012
 Identities = 52/214 (24%), Positives = 87/214 (40%), Gaps = 26/214 (12%)

Query  39   SNNAKEAVEHLQKS-ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            SN    AVE L K  +   + N   QD L E EQ + Q       ME+ + E    L+  
Sbjct  300  SNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQ-------MEKEMLEKIGRLEKE  352

Query  98   LRPHADELKAKIDQNV---EELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
            L    D L A   +     EE    ++P A     KI +   +L      Y +   + L 
Sbjct  353  LENANDLLSATKRKGAILSEEELAAMSPTAAAV-AKIVKPGMKLTELYNAYVETQDQLLL  411

Query  155  HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
             +LE    ++ K  +E+   + A A  L+++            R   E  QK++A L   
Sbjct  412  EKLENK--RINKYLDEIVKEVEAKAPILKRQ------------REEYERAQKAVASLSVK  457

Query  215  LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
            L+Q ++E +R  E   +   ++ V + +  R ++
Sbjct  458  LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEI  491


 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 42/190 (22%), Positives = 84/190 (44%), Gaps = 11/190 (5%)

Query  83   MERVL-RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS  141
            +++VL R   + L  S++   ++  A     ++ LKGR     ++FKV+ +Q   E+ + 
Sbjct  5    LQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGR----HEKFKVESEQQYFEIEKR  60

Query  142  LAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE-ELRQRLAPLAEDVRGNLRGN  200
            L+ ++Q+       + + L  +++K   +LKA    + E E+ Q      +      +  
Sbjct  61   LS-HSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEE  119

Query  201  TEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP-HAGDVEGHL  259
             E  ++ L      L Q++E     V+   E   ++   + E L+ KL    A DV   +
Sbjct  120  LEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE-LQLKLDELQASDVS--V  176

Query  260  SFLEKDLRDK  269
             + EK L  +
Sbjct  177  KYREKRLEQE  186


 Score = 32.0 bits (71),  Expect = 0.40
 Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 12/142 (8%)

Query  71   QLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVK  130
            ++ ++L+   +R+    RE   SL+  L    ++LKA  ++N E         A +  + 
Sbjct  56   EIEKRLSHSQERLVNETRE-CQSLRLELEKLNNQLKALTEKNKE------LEIAQDRNIA  108

Query  131  IDQTVEELRRSLAPYAQD---TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA  187
            I       +  L    +D   T E+L+ +LE LT  +K+  E+LK   + +  EL+ +L 
Sbjct  109  IQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLK-ESNTTKGELQLKLD  167

Query  188  PL-AEDVRGNLRGNTEGLQKSL  208
             L A DV    R      +K L
Sbjct  168  ELQASDVSVKYREKRLEQEKEL  189


>gi|266902|sp|P30622|REST_HUMAN  Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg 
intermediate filament associated protein) (Cytoplasmic 
linker protein 1)
Length=1427

 Score = 47.8 bits (112),  Expect = 7e-06
 Identities = 48/205 (23%), Positives = 104/205 (50%), Gaps = 20/205 (9%)

Query  33    DYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
             + F+ LS++ ++  E+L   E      A F++K    EQL +        +  +++ + D
Sbjct  875   EQFNMLSSDLEKLRENLADME------AKFREKDEREEQLIKAKEKLENDIAEIMKMSGD  928

Query  93    SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL-------RRSLAPY  145
             +  + L    DEL+ K +++VEEL+ +LT  A+E    + +++E++       ++  A  
Sbjct  929   N-SSQLTKMNDELRLK-ERDVEELQLKLTK-ANENASFLQKSIEDMTVKAEQSQQEAAKK  985

Query  146   AQDTQEKLNHQLEGLTFQMKKN---AEELKARISASAEELRQRLAPLAEDVRGNLRGNTE  202
              ++ +++L  +L  L  +M+ +    +ELKAR   +  E + +   + ++++  L  +TE
Sbjct  986   HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLL-DTE  1044

Query  203   GLQKSLAELGGHLDQQVEEFRRRVE  227
                K   E    L Q++EE R++ +
Sbjct  1045  DKLKGAREENSGLLQELEELRKQAD  1069


 Score = 34.7 bits (78),  Expect = 0.061
 Identities = 43/222 (19%), Positives = 90/222 (40%), Gaps = 15/222 (6%)

Query  56    QQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEE  115
             Q+L A ++    E +    ++    Q +++ L +  D L+ +   ++  L+   +   + 
Sbjct  1012  QELKARYERATSETKTKHEEIL---QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQA  1068

Query  116   LKGRLTPYADEFKVKIDQTVEELRRSLAPY--AQDTQEKLNHQLEGLTFQMKKNAEELKA  173
              K +    A++    ++Q  +E   +LA     + T  KL ++L+ L     KN EEL  
Sbjct  1069  DKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNK  1128

Query  174   RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF  233
                       + L  +        R   E L+++ A+    L    EE  +  E  G + 
Sbjct  1129  ---------SKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSR  1179

Query  234   NKALV-QQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLR  274
             ++    Q++E+ R  L     +++   S   KD  ++   L+
Sbjct  1180  DEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQ  1221


>gi|1346640|sp|P35580|MYH10_HUMAN  Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin 
heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin 
heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B)
Length=1976

 Score = 47.8 bits (112),  Expect = 7e-06
 Identities = 46/213 (21%), Positives = 95/213 (44%), Gaps = 13/213 (6%)

Query  36    SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
             SQL+   ++A    +     + + +  +++L + E+ R++L    ++++    +  D + 
Sbjct  1013  SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQI-  1071

Query  96    ASLRPHADELKAKIDQNVEELKGRLTPYADE--FKVKIDQTVEELRRSLAPYAQDTQEKL  153
             A L+   DELK ++ +  EEL+G L    DE   K    + V EL+  +A   +D + + 
Sbjct  1072  AELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEK  1131

Query  154   NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG  213
                        +  AE+ K  +S   E L+  L    +         T+  ++ +AEL  
Sbjct  1132  ---------ASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTK-REQEVAELKK  1181

Query  214   HLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ  246
              L+++ +    +++   +    AL +  EQL Q
Sbjct  1182  ALEEETKNHEAQIQDMRQRHATALEELSEQLEQ  1214


 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 51/202 (25%), Positives = 95/202 (47%), Gaps = 29/202 (14%)

Query  54   LTQQLNALFQDKLGEAEQLRRQLTPYAQRME----RVLRENADSLQASLRPHADELKAKI  109
            L ++  A  Q +L   + L+R    Y +       RV  +    LQ + +   +EL+AK 
Sbjct  801  LARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQE--EELQAK-  857

Query  110  DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK--LNHQLEGLTFQMKKN  167
            D+ + ++K + T        K++  +EE+ R    + Q  +EK  L  QL+  T ++   
Sbjct  858  DEELLKVKEKQT--------KVEGELEEMERK---HQQLLEEKNILAEQLQAET-ELFAE  905

Query  168  AEELKARISASAEELRQRLAPLAEDVRGN------LRGNTEGLQKSLAELGGHLDQQVEE  221
            AEE++AR++A  +EL + L  L   V         L+   + +Q  + +L   LD+  EE
Sbjct  906  AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE--EE  963

Query  222  FRRRVEPYGENFNKALVQQMEQ  243
              R+     +   +A +++ME+
Sbjct  964  GARQKLQLEKVTAEAKIKKMEE  985


 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 42/213 (19%), Positives = 86/213 (40%), Gaps = 16/213 (7%)

Query  29    TVMWDYFSQLSNNAKEAVEHLQKSELTQQL-NALFQDKLGEAEQLRRQLTPYAQRMERVL  87
             + + D   +L     +  E L++ +   +L N  F+    + + L  +L       ER  
Sbjct  1725  SALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA-----ERSA  1779

Query  88    RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ  147
              + +D+ +  L     ELKAK+ +    +K +        + KI Q  E+L +     A 
Sbjct  1780  AQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAA  1839

Query  148   DTQ--EKLNHQLEGLTFQM---KKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNT-  201
               +   +   +L+ +  Q+   +++A++ K ++  +   ++Q    L E      R N  
Sbjct  1840  ANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANAS  1899

Query  202   -EGLQKSL---AELGGHLDQQVEEFRRRVEPYG  230
                LQ+ L    E    L ++V   + R+   G
Sbjct  1900  RRKLQRELDDATEANEGLSREVSTLKNRLRRGG  1932


 Score = 32.0 bits (71),  Expect = 0.40
 Identities = 48/252 (19%), Positives = 104/252 (41%), Gaps = 26/252 (10%)

Query  47    EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             E  +K      L    ++ L   E+  RQ       ME ++  + D +  ++    ++ K
Sbjct  1477  EAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM-SSKDDVGKNVH-ELEKSK  1534

Query  107   AKIDQNVEELKGRLTPYADEFKVKIDQTVE---ELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
               ++Q VEE++ +L    DE +   D  +     ++   A + +D Q + + Q E     
Sbjct  1535  RALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR-DEQNEEKKRL  1593

Query  164   MKKNAEELKARISASAEELRQRLAPLA---------EDVRGNLRGNTEGLQKSLAELGGH  214
             + K   EL+A +    +E +QR   +A         +D+   +    +   + + +L   
Sbjct  1594  LIKQVRELEAELE---DERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQL-RK  1649

Query  215   LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLR  274
             L  Q+++++R +E    + ++   Q  E  ++        +E  +  L+++L       R
Sbjct  1650  LQAQMKDYQRELEEARASRDEIFAQSKESEKK-----LKSLEAEILQLQEELASSERARR  1704

Query  275   LG--DRDESGEE  284
                 +RDE  +E
Sbjct  1705  HAEQERDELADE  1716


>gi|71151982|sp|Q7Z406|MYH14_HUMAN  Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin 
heavy chain IIc) (NMHC II-C)
Length=1995

 Score = 47.8 bits (112),  Expect = 7e-06
 Identities = 62/249 (24%), Positives = 108/249 (43%), Gaps = 35/249 (14%)

Query  34    YFSQLSNNAKEAVEHLQKSEL-TQQLNALFQDKLGEAEQLRRQLTPYAQRMERV---LRE  89
             Y S +   ++   + L+K E   Q+L  L +   GE+ +L+ Q+    QR E +   L  
Sbjct  1045  YGSNMRPQSQTWRDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGR  1104

Query  90    NADSLQASLRPHADE--LKAKIDQNVEELKGRLTPYADEFKVK-------------IDQT  134
               + LQA+L    DE   +A++ +++ E +  L    ++ + +             + + 
Sbjct  1105  KEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE  1164

Query  135   VEELRRSLAPYAQDT--QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR----LAP  188
             +E LR  L      T  Q++L  + E    ++KK  EE      A+ +ELRQR    L  
Sbjct  1165  LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE  1224

Query  189   LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
             LAE +    RG     +  LA     L+ +V E R  +        +   Q+ EQ R++L
Sbjct  1225  LAEQLEQARRGKGAWEKTRLA-----LEAEVSELRAELSSL-----QTARQEGEQRRRRL  1274

Query  249   GPHAGDVEG  257
                  +V+G
Sbjct  1275  ELQLQEVQG  1283


 Score = 37.4 bits (85),  Expect = 0.009
 Identities = 49/173 (28%), Positives = 79/173 (45%), Gaps = 32/173 (18%)

Query  79    YAQRMERVLRENAD-SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEE  137
             + +++ R  R  A  S  +++RP +   +   D+  +E KGR             Q +E+
Sbjct  1029  HPRQLRRRRRSRASISYGSNMRPQSQTWR---DRLRKEEKGR-------------QELEK  1072

Query  138   LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL  197
             L+R L   + + QE++  Q        ++ AEEL+A++    EEL+  LA  AED  G  
Sbjct  1073  LKRRLDGESSELQEQMVEQ--------QQRAEELRAQLGRKEEELQAALA-RAED-EGGA  1122

Query  198   RGNTEGLQKSLAELGGHLDQQVE--EFRRRVEPYGENFNKALVQQMEQLRQKL  248
             R     L KSL E    L +  E  E  R      E   + L +++E LR +L
Sbjct  1123  RAQ---LLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGEL  1172


 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 52/248 (20%), Positives = 110/248 (44%), Gaps = 27/248 (10%)

Query  57    QLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEEL  116
             QL    +++   +E L  +      ++E +  E   S + S    A+  + ++++ ++EL
Sbjct  1757  QLEEELEEEQSNSELLNDRYRKLLLQVESLTTEL--SAERSFSAKAESGRQQLERQIQEL  1814

Query  117   KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS  176
             +GRL       + +   T+  L   LA   +  +++   ++  L+ ++ + AE+    + 
Sbjct  1815  RGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI--LSGKLVRRAEKRLKEVV  1872

Query  177   ASAEELRQRLAPLAEDV-RGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN-  234
                EE R+    L + + +GNLR   + L++ L E       + +  RRR++   E+   
Sbjct  1873  LQVEEERRVADQLRDQLEKGNLR--VKQLKRQLEEAEEEA-SRAQAGRRRLQRELEDVTE  1929

Query  235   --KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGEEGQSRGMQA  292
               +++ +++  LR +L        G L+F  + +R      RL       EEG +   +A
Sbjct  1930  SAESMNREVTTLRNRLR------RGPLTFTTRTVRQV---FRL-------EEGVASDEEA  1973

Query  293   LQGFPGRG  300
              +  PG G
Sbjct  1974  EEAQPGSG  1981


 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 53/246 (21%), Positives = 105/246 (42%), Gaps = 42/246 (17%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA--------SLRPH  101
             +K EL   ++ L + ++GE E+  RQ+    +R+++ ++E    L+A         L   
Sbjct  933   RKQELELVVSEL-EARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKV  991

Query  102   ADELKAKIDQN----VEELKGRLTPYADEFKVKIDQT-VEELRR------------SLAP  144
               E K K  +     +E+   +L+     +K+    +   +LRR            ++ P
Sbjct  992   TTEAKMKKFEEDLLLLEDQNSKLSKSGSCWKIVWPSSHPRQLRRRRRSRASISYGSNMRP  1051

Query  145   YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA---PLAEDVRGNLRGNT  201
              +Q  +++L  + +G     ++  E+LK R+   + EL++++      AE++R  L    
Sbjct  1052  QSQTWRDRLRKEEKG-----RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKE  1106

Query  202   EGLQKSLA---ELGGHLDQQVEEFRRRVEPYGE-----NFNKALVQQMEQLRQKLGPHAG  253
             E LQ +LA   + GG   Q ++  R       E        +    + E+ R+ LG    
Sbjct  1107  EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELE  1166

Query  254   DVEGHL  259
              + G L
Sbjct  1167  ALRGEL  1172


 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 28/117 (23%), Positives = 55/117 (47%), Gaps = 12/117 (10%)

Query  156   QLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL  215
             +L+G   Q+++    L  ++ A AE     L   AE+ RG L    + L+  ++EL   +
Sbjct  894   ELQGRVAQLEEERARLAEQLRAEAE-----LCAEAEETRGRLAARKQELELVVSELEARV  948

Query  216   ------DQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL  266
                    +Q++  ++R++ + +   +A ++  E  RQKL       E  +   E+DL
Sbjct  949   GEEEECSRQMQTEKKRLQQHIQEL-EAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL  1004


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 57/252 (22%), Positives = 97/252 (38%), Gaps = 20/252 (7%)

Query  44    EAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD  103
             EA E LQ+++   +        L EAE    +L+      E  L +  + LQ   R    
Sbjct  1294  EAAEKLQRAQAELEN---VSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA---  1347

Query  104   ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
               K  +   V  ++       ++ + +        R      AQ ++ +   + E    +
Sbjct  1348  --KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE  1405

Query  164   MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
                  EE + R +  AE L QRLA   E V    RG    LQ+ L +    L+QQ  +  
Sbjct  1406  A---GEEARRRAAREAEALTQRLAEKTETVDRLERGRRR-LQQELDDATMDLEQQ-RQLV  1460

Query  224   RRVEPYGENFNKALVQQMEQ-LRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESG  282
               +E     F++ L ++    LR        + EG     E++ R  +    L +  E+ 
Sbjct  1461  STLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGR----EREARALSLTRALEEEQEAR  1516

Query  283   E--EGQSRGMQA  292
             E  E Q+R ++A
Sbjct  1517  EELERQNRALRA  1528


>gi|6166599|sp|P35579|MYH9_HUMAN  Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin 
heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin 
heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A)
Length=1960

 Score = 47.0 bits (110),  Expect = 1e-05
 Identities = 59/248 (23%), Positives = 107/248 (43%), Gaps = 33/248 (13%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLR--PHADELKA  107
             +K +L +QL A   +   EAE+LR +LT   Q +E +  +    ++       H    K 
Sbjct  881   EKLQLQEQLQAE-TELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK  939

Query  108   KIDQNVEELKGRL---------------TPYADEFKVKIDQTV-EELRRSLAPYAQDTQE  151
             K+ QN++EL+ +L               T  A   K++ +Q + E+    LA   +  ++
Sbjct  940   KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLED  999

Query  152   KLNHQLEGLTFQMKKNAE--ELKARISASAEELRQRL------APLAEDVRGNLRGNTEG  203
             ++      LT + +K+    +LK +  A   +L +RL          E  R  L G++  
Sbjct  1000  RIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTD  1059

Query  204   LQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK--LGPHAGDVEGHLSF  261
             L   +AE    L  Q+ E + ++    E    AL +  E+  QK        ++E  +S 
Sbjct  1060  LSDQIAE----LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISE  1115

Query  262   LEKDLRDK  269
             L++DL  +
Sbjct  1116  LQEDLESE  1123


 Score = 43.5 bits (101),  Expect = 1e-04
 Identities = 51/218 (23%), Positives = 102/218 (46%), Gaps = 18/218 (8%)

Query  44    EAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADS-----LQASL  98
             +A E+ +K +  +      Q++L  AE+ +RQ     Q  + +  E A+S     L    
Sbjct  1667  QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ---QERDELADEIANSSGKGALALEE  1723

Query  99    RPHADELKAKIDQNVEELKGRLTPYADEFK---VKIDQ--TVEELRRSLAPYAQDTQEKL  153
             +   +   A++++ +EE +G      D  K   ++IDQ  T   L RS A   ++ +++L
Sbjct  1724  KRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL  1783

Query  154   NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG  213
               Q + L  ++++    +K++  AS   L  ++A L E +    +   +   K +     
Sbjct  1784  ERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETK-ERQAACKQVRRTEK  1842

Query  214   HLDQ---QVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
              L     QV++ RR  E Y +  +KA   +++QL+++L
Sbjct  1843  KLKDVLLQVDDERRNAEQYKDQADKAST-RLKQLKRQL  1879


 Score = 36.2 bits (82),  Expect = 0.021
 Identities = 42/199 (21%), Positives = 85/199 (42%), Gaps = 14/199 (7%)

Query  29    TVMWDYFSQLSNNAKEAVEHLQKS-ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVL  87
             T+   Y  +      EA E   K+  L + L    + K  E E+L +Q   +   ME ++
Sbjct  1455  TISAKYAEERDRAEAEAREKETKALSLARALEEAMEQK-AELERLNKQ---FRTEMEDLM  1510

Query  88    RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ  147
               + D +  S+    ++ K  ++Q VEE+K +L    DE      Q  E+ +  L    Q
Sbjct  1511  -SSKDDVGKSVH-ELEKSKRALEQQVEEMKTQLEELEDEL-----QATEDAKLRLEVNLQ  1563

Query  148   DTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL--RQRLAPLAEDVRGNLRGNTEGLQ  205
               + +    L+G   Q ++  ++L  ++     EL   ++   +A   R  L  + + L+
Sbjct  1564  AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE  1623

Query  206   KSLAELGGHLDQQVEEFRR  224
               +     + D+ +++ R+
Sbjct  1624  AHIDSANKNRDEAIKQLRK  1642


 Score = 34.7 bits (78),  Expect = 0.061
 Identities = 48/224 (21%), Positives = 94/224 (41%), Gaps = 25/224 (11%)

Query  47    EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             E  Q+ EL +    L  D    ++Q+  +L      ++  L +  + LQA+L    +E  
Sbjct  1039  EEKQRQELEKTRRKLEGDSTDLSDQIA-ELQAQIAELKMQLAKKEEELQAALARVEEEAA  1097

Query  107   AK---------IDQNVEELKGRLTPY------ADEFKVKIDQTVEELRRSLAPYAQDT--  149
              K         ++  + EL+  L         A++ K  + + +E L+  L      T  
Sbjct  1098  QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA  1157

Query  150   QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL------RGNTEG  203
             Q++L  + E     +KK  EE      A  +E+RQ+ +   E++   L      + N E 
Sbjct  1158  QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEK  1217

Query  204   LQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
              +++L    G L  +V+   +  +   E+  K +  Q+++L+ K
Sbjct  1218  AKQTLENERGELANEVKVLLQG-KGDSEHKRKKVEAQLQELQVK  1260


 Score = 33.9 bits (76),  Expect = 0.10
 Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 31/160 (19%)

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQ-EKLNHQLEGLTFQMKKN----------AEELKA  173
            +E   K ++ V+   + LA   + T+ E L  QL     Q+++           AEEL+A
Sbjct  845  EEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRA  904

Query  174  RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF  233
            R++A  +EL +    +  D+   +    E  Q        HL  + ++ ++ ++   E  
Sbjct  905  RLTAKKQELEE----ICHDLEARVEEEEERCQ--------HLQAEKKKMQQNIQELEEQ-  951

Query  234  NKALVQQMEQLRQKLGPHAGDVEGHLSFLEKD---LRDKN  270
                +++ E  RQKL       E  L  LE++   L D+N
Sbjct  952  ----LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN  987


 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 39/153 (25%), Positives = 73/153 (47%), Gaps = 12/153 (7%)

Query  48    HLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKA  107
             +LQ  ++   LN L +    + E  R+QL    + ++  L+E   ++++  +     L+A
Sbjct  1756  NLQIDQINTDLN-LERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEA  1814

Query  108   KIDQNVEELKGRLTP--------YADEFKVK-IDQTVEELRRSLAPYAQDTQEKLNHQLE  158
             KI Q  E+L                 E K+K +   V++ RR+   Y +D  +K + +L+
Sbjct  1815  KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQY-KDQADKASTRLK  1873

Query  159   GLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
              L  Q+++ AEE   R +AS  +L++ L    E
Sbjct  1874  QLKRQLEE-AEEEAQRANASRRKLQRELEDATE  1905


>gi|28201804|sp|Q14789|GOGB1_HUMAN  Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa 
Golgi complex-associated protein) (GCP372)
Length=3259

 Score = 45.8 bits (107),  Expect = 3e-05
 Identities = 49/206 (23%), Positives = 95/206 (46%), Gaps = 16/206 (7%)

Query  43    KEAVEHLQKSEL-------TQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLR--ENADS  93
             KE +E +Q ++         ++L  L ++K  E +QL++    Y +++  + R  +  + 
Sbjct  1988  KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF  2047

Query  94    LQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL  153
             +Q   +   +  K  + Q VE  K      A  FKV +D T  E  R LA   +  +++L
Sbjct  2048  VQTESQKDLEITKENLAQAVEHRKKAQAELAS-FKVLLDDTQSEAARVLADNLK-LKKEL  2105

Query  154   NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG  213
                 E +  QMK+  E+L+ R+   AEE   +     ++    LR     L++++ E+  
Sbjct  2106  QSNKESVKSQMKQKDEDLERRLE-QAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV  2164

Query  214   HLDQQVEEFRRRVEPYGENFNKALVQ  239
              L+++ +E    V+   EN +  + Q
Sbjct  2165  TLNKKDKE----VQQLQENLDSTVTQ  2186


 Score = 43.5 bits (101),  Expect = 1e-04
 Identities = 61/278 (21%), Positives = 116/278 (41%), Gaps = 20/278 (7%)

Query  32    WDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
             +D  S     +KE ++H  + +L ++ N   + KL  A   R++L     R+E  L    
Sbjct  963   YDEMSPAGQISKEELQH--EFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLK  1020

Query  92    DSLQASLRPHADELKAKIDQ---NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD  148
             D  +  + P ++  + ++++   N E  +  +T    E ++ + QT+ E    L    +D
Sbjct  1021  DESKKEI-PLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKD  1079

Query  149   TQEKL--NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL---RGNTEG  203
              +EKL    Q + L  QM +  ++   +I     E+ +  A + + +  N     G++  
Sbjct  1080  LEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVA  1139

Query  204   LQKSLAEL-------GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE  256
             L K    +         H   ++EE    +E   E   K L Q+    R+ +   A + E
Sbjct  1140  LVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKL-QEALTSRKAILKKAQEKE  1198

Query  257   GHLSFLEKDLRDKNWGLRLGDRDESGEEGQSRGMQALQ  294
              HL    K  +D ++       DE  +E ++ G Q  Q
Sbjct  1199  RHLREELKQQKD-DYNRLQEQFDEQSKENENIGDQLRQ  1235


 Score = 39.7 bits (91),  Expect = 0.002
 Identities = 50/239 (20%), Positives = 108/239 (45%), Gaps = 34/239 (14%)

Query  26    QVATVMWDYFSQLSNNAKEAVEHLQKSE-----LTQQLNALFQDKLGEAEQLRRQLTPYA  80
             Q+  V      +L N   +  E L++SE     L +  NAL ++K   ++++       +
Sbjct  2553  QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSIS  2612

Query  81    QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL--  138
             Q   +V    A   + +L  +  +LK K     EE   RL+      + +I +  EEL  
Sbjct  2613  QLTRQV---TALQEEGTLGLYHAQLKVK-----EEEVHRLSALFSSSQKRIAELEEELVC  2664

Query  139   -RRSLAPYAQDTQEKLNHQLE------GLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
              ++  A    + ++KL  +L+      G+     + AEE  A ++    E+ Q+L  + +
Sbjct  2665  VQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK  2724

Query  192   DVRGNLRGNTEGLQKSLAELGG---HLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
             + +G L    +   +S++ L     H +++++E +R+ +        A ++++ QL+++
Sbjct  2725  ENKG-LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYD--------ASLKELAQLKEQ  2774


 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 58/239 (24%), Positives = 101/239 (42%), Gaps = 41/239 (17%)

Query  23    SADQVATVMWDYFSQLSNNAKEAVEHLQK-----SELTQQLNALFQ-----DKLGEAEQL  72
             SA Q  T +    +QL     E VE   K     SELT++   +FQ     +K G   + 
Sbjct  1296  SALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIES  1355

Query  73    RRQLTPYAQRMERVLRENADSLQAS---------LRPHADELK---AKIDQNVEELKGRL  120
              + ++  A+     L++  +S Q           L+P  DEL+   +K +++V  L G+L
Sbjct  1356  LKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQL  1415

Query  121   TPYADEFK------VKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKAR  174
             +             ++ +  ++ L   L   A++  E++  QL+    +MK+  EE+   
Sbjct  1416  SEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIK-QLQVELCEMKQKPEEIGEE  1474

Query  175   ISASAEELRQRLAPLA---EDVRGN---------LRGNTEGLQKSLAELGGHLDQQVEE  221
               A  +  R+  A L    E ++ N          RG  E L KSLA++   +  Q +E
Sbjct  1475  SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE  1533


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 43/213 (20%), Positives = 95/213 (44%), Gaps = 35/213 (16%)

Query  36    SQLSNNAKEAVEHL--QKSELTQQLNALFQDKLGEA-------EQLRRQLTPYAQRMERV  86
             S    + K A+E L   K +L +++ +L   K+ E+       ++L+++     Q  E V
Sbjct  1566  SSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENV  1625

Query  87    LRENADSLQ---ASLRPHADELKAKI---DQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
               E A+ +Q    ++R    EL  K+   + N +E + +L         + +Q +EE++ 
Sbjct  1626  SNE-AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ--------EAEQEMEEMKE  1676

Query  141   SLAPYAQDTQEKL------NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVR  194
              +  +A+  Q+K+      N +L          A+E    + +S   +++ L    E V+
Sbjct  1677  KMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEEL----ERVK  1732

Query  195   GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVE  227
                   ++  Q  ++E    L ++V++ + ++E
Sbjct  1733  MEYETLSKKFQSLMSEKDS-LSEEVQDLKHQIE  1764


 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 54/240 (22%), Positives = 99/240 (41%), Gaps = 34/240 (14%)

Query  36   SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQL--TPYAQRMERVLRENADS  93
            +Q    A+ + E  +   + QQL    Q+K      L+ QL  T   Q  ++V+RE    
Sbjct  170  AQAEQPAQSSTEMEEFVMMKQQL----QEKEEFISTLQAQLSQTQAEQAAQQVVREKDAR  225

Query  94   LQASLRPHADEL---------KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP  144
             +  +R H DEL         + ++ Q +  L+ +L  + +E  V   Q V+ L++ L  
Sbjct  226  FETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH-EESLVGRAQVVDLLQQELTA  284

Query  145  YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL  204
             A+   + L+ QL+    QM+     L+  +    EE +  L  +  +V    + +   L
Sbjct  285  -AEQRNQILSQQLQ----QMEAEHNTLRNTVETEREESKILLEKMELEV-AERKLSFHNL  338

Query  205  QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK  264
            Q+ +  L       +E+F +  +   E     L  +   L QK      +   H+  L+K
Sbjct  339  QEEMHHL-------LEQFEQAGQAQAE-----LESRYSALEQKHKAEMEEKTSHILSLQK  386


 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 51/230 (22%), Positives = 95/230 (41%), Gaps = 38/230 (16%)

Query  45    AVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE  104
             A E+ +  E  + L +   D   E  +L  +L  Y + + +V+    DS Q  L      
Sbjct  2502  AAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIK-DSQQKQL------  2554

Query  105   LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF--  162
             L+ ++ QN +EL+ +     ++ K + ++  E+LRRS     ++ Q+ L+ ++E L    
Sbjct  2555  LEVQLQQN-KELENKYAKLEEKLK-ESEEANEDLRRSFNALQEEKQD-LSKEIESLKVSI  2611

Query  163   ---------------------QMKKNAEELKARISASAEELRQRLAPLAED---VRGNLR  198
                                  Q+K   EE+  R+SA     ++R+A L E+   V+    
Sbjct  2612  SQLTRQVTALQEEGTLGLYHAQLKVKEEEVH-RLSALFSSSQKRIAELEEELVCVQKEAA  2670

Query  199   GNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
                  ++  L +   HL       R   E   E   + L + + ++ QKL
Sbjct  2671  KKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAE-LARDLVEMEQKL  2719


 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 34/182 (18%), Positives = 73/182 (40%), Gaps = 26/182 (14%)

Query  37    QLSNNAKEAVEHLQKSE----LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
             +L +  K+  E L   E    L +Q+N   QDK  + + L+ +++     +++++  N D
Sbjct  1072  ELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTD  1131

Query  93    SLQAS----------LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
             +              + P            +EE    L    ++ + K+ + +   R+++
Sbjct  1132  ASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTS-RKAI  1190

Query  143   APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEE-------LRQRLAPLAEDVRG  195
                AQ+ +  L  +L+    Q K +   L+ +    ++E       LRQ    + E + G
Sbjct  1191  LKKAQEKERHLREELK----QQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG  1246

Query  196   NL  197
              L
Sbjct  1247  KL  1248


 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 18/111 (16%)

Query  101  HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL  160
            H DEL+ ++   + EL+       + ++  +D+  +E+              LN  +E  
Sbjct  682  HQDELE-RLKSQILELELNFHKAQEIYEKNLDEKAKEI------------SNLNQLIE--  726

Query  161  TFQMKKNAEELKARISASAEELRQRLAPLAE-DVRGNLRGNTEGLQKSLAE  210
              + KKNA+   +  +A +EE  Q L+ + E  +   LR   + L+ +LAE
Sbjct  727  --EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAE  775


 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 61/274 (22%), Positives = 111/274 (40%), Gaps = 69/274 (25%)

Query  46    VEHLQKSELTQQLNALFQDKL-GEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE  104
             +E  +KSE  +Q +A        E + L++ ++      +R+L+E  +  Q  L+     
Sbjct  2852  LEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-----  2906

Query  105   LKAKIDQNVEEL---KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT  161
                 I+Q + EL   K +L  Y D  K K  Q ++E  R         QE L+ Q E   
Sbjct  2907  ----INQEITELHPLKAQLQEYQD--KTKAFQIMQEELR---------QENLSWQHELHQ  2951

Query  162   FQMKKNAEELKAR---------ISASAEELRQRLAPLAEDVRGN----------------  196
              +M+K++ E+  R         IS   ++L   L  L  ++R +                
Sbjct  2952  LRMEKSSWEIHERRMKEQYLMAISDKDQQL-SHLQNLIRELRSSSSQTQPLKVQYQRQAS  3010

Query  197   --LRGNTEGLQKSLAE---LGGHLDQQVEEFRR---RVEPYGENFNKALVQQ--------  240
                  + +G Q  + E   L   L+  ++E  +   R++    NF++ L ++        
Sbjct  3011  PETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLC  3070

Query  241   --MEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWG  272
                + LR+    H GD+  H + LEK +++   G
Sbjct  3071  DTSQSLRENQ-QHYGDLLNHCAVLEKQVQELQAG  3103


>gi|83304912|sp|P12883|MYH7_HUMAN  Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta)
Length=1935

 Score = 45.8 bits (107),  Expect = 3e-05
 Identities = 56/214 (26%), Positives = 94/214 (43%), Gaps = 45/214 (21%)

Query  43    KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRP--  100
             K A E+  K+ LT+++  L        +++  +LT   + ++   ++  D LQA      
Sbjct  968   KHATENKVKN-LTEEMAGL--------DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN  1018

Query  101   HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK--------  152
                + K K++Q V++L+G L     E KV++D  +E  +R L    + TQE         
Sbjct  1019  TLTKAKVKLEQQVDDLEGSLE---QEKKVRMD--LERAKRKLEGDLKLTQESIMDLENDK  1073

Query  153   ----------------LNHQLE---GLTFQMKKNAEELKARISASAEELRQRLAPLA--E  191
                             LN ++E    L  Q++K  +EL+ARI    EEL       A  E
Sbjct  1074  QQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE  1133

Query  192   DVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR  225
              +R +L    E + + L E GG    Q+E  ++R
Sbjct  1134  KLRSDLSRELEEISERLEEAGGATSVQIEMNKKR  1167


 Score = 34.7 bits (78),  Expect = 0.061
 Identities = 46/205 (22%), Positives = 90/205 (43%), Gaps = 30/205 (14%)

Query  47    EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             E ++ SE  Q L++     + + +++   L+     +E  ++E  ++ + + +   D   
Sbjct  1705  ELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM  1764

Query  107   AKIDQNVEELKGR--LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM  164
                    EELK     + + +  K  ++QT+++L+  L     D  E++   L+G     
Sbjct  1765  M-----AEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-----DEAEQI--ALKG----G  1808

Query  165   KKNAEELKARISASAEELRQRLAPLAEDVRG---------NLRGNTEGLQKSLAELGGHL  215
             KK  ++L+AR+     EL       AE V+G          L   TE  +K+L  L   +
Sbjct  1809  KKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLV  1868

Query  216   DQ---QVEEFRRRVEPYGENFNKAL  237
             D+   +V+ ++R+ E   E  N  L
Sbjct  1869  DKLQLKVKAYKRQAEEAEEQANTNL  1893


 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 39/174 (22%), Positives = 78/174 (44%), Gaps = 35/174 (20%)

Query  36    SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQ--LTPYAQRMERVLRENADS  93
             SQL    +EAV+  + +E  ++      D    AE+L+++   + + +RM++ + +    
Sbjct  1735  SQLQTEVEEAVQECRNAE--EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD  1792

Query  94    LQ----------------------ASLRPHADELKAKIDQNVEELKGRLTPYADEFKVK-  130
             LQ                      A +R   +EL+A+  +N E +KG       E ++K 
Sbjct  1793  LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGM---RKSERRIKE  1849

Query  131   IDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
             +    EE R++L    QD  +KL  +++      K+ AEE + + + +  + R+
Sbjct  1850  LTYQTEEDRKNLL-RLQDLVDKLQLKVKA----YKRQAEEAEEQANTNLSKFRK  1898


>gi|12643718|sp|Q13439|GOGA4_HUMAN  Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) 
(Golgin-245) (Protein 72.1)
Length=2230

 Score = 45.8 bits (107),  Expect = 3e-05
 Identities = 52/258 (20%), Positives = 110/258 (42%), Gaps = 28/258 (10%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADS---  93
            Q  + A E +E  +K+ LT+  N L +D   EAE  R ++      +E+ L+EN +    
Sbjct  531  QQESLALEELELQKKAILTESENKL-RDLQQEAETYRTRILELESSLEKSLQENKNQSKD  589

Query  94   ----LQASLRPHADELKAKIDQNVEELKG-----------RLTPYADEFKVKIDQTVEEL  138
                L+A    H  E+   ++++  EL+            +L     +++ ++++  E+ 
Sbjct  590  LAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKC  649

Query  139  RRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL--AEDVRGN  196
             +      +D +      +E +  +  +  +  +  + + + EL + L      E+    
Sbjct  650  EQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSV  709

Query  197  LRGNTEGLQKSLA----ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR---QKLG  249
            L+  T+ +++ L     E   H  QQV+   +  E   +   KAL  Q+ QL    ++  
Sbjct  710  LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERD  769

Query  250  PHAGDVEGHLSFLEKDLR  267
             H  + + H+  LE D++
Sbjct  770  KHLKEHQAHVENLEADIK  787


 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 58/257 (22%), Positives = 111/257 (43%), Gaps = 25/257 (9%)

Query  26   QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQ-LRRQLTPYAQRME  84
            Q+ T   +   Q   + + A E L+K+  T Q       K  EA + L+ ++    + +E
Sbjct  393  QMTTQGEELREQKEKSERAAFEELEKALSTAQ-------KTEEARRKLKAEMDEQIKTIE  445

Query  85   RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP  144
            +   E   SLQ  L     E+   + ++ EE   +L    ++   + +Q   EL + L  
Sbjct  446  KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ---ELTKKLQT  502

Query  145  YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL---RQRLAPLAEDVRGNLRGNT  201
              ++ QE++   LE    +  K ++E + + S + EEL   ++ +   +E+   +L+   
Sbjct  503  REREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA  562

Query  202  EGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPH-AGDVEGHLS  260
            E  +  + EL   L++ ++E         +N +K L   +E  + K        VE H +
Sbjct  563  ETYRTRILELESSLEKSLQE--------NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT  614

Query  261  FLE--KDLRDKNWGLRL  275
             LE  K  +D  W  +L
Sbjct  615  ELESLKHQQDALWTEKL  631


 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 46/220 (20%), Positives = 96/220 (43%), Gaps = 26/220 (11%)

Query  41    NAKEAVEH---LQKSELTQQLNALFQDKLGEAEQ--LRRQLTPYAQRME-RVLRENADSL  94
             N ++ +EH   +QK +  Q+L     +++ EAE+  L  +   Y+ + E    ++  + +
Sbjct  1552  NQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHV  1611

Query  95    QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
               S++   +ELKA  D+   E   +L     E K K +Q +  +++ L            
Sbjct  1612  NLSVKSKEEELKALEDRLESESAAKLA----ELKRKAEQKIAAIKKQLLS----------  1657

Query  155   HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL--QKSLAELG  212
              Q+E    Q KK  E   + ++   +E  + +  L E ++      +E L   +S   + 
Sbjct  1658  -QMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA  1716

Query  213   GHLDQQVEEFRRRVEPYGENFNKAL---VQQMEQLRQKLG  249
              + +Q+  + +  V+   E     L   + + E+L Q++G
Sbjct  1717  AYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVG  1756


 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 46/225 (20%), Positives = 96/225 (42%), Gaps = 23/225 (10%)

Query  43    KEAVEHLQKSELT---QQLNALFQ-DKLGEAEQLRRQLTPYAQRMERVLRENADSLQASL  98
             ++ V  ++  ELT   ++L AL Q D   +  +L  + T    +   V  +   +++A  
Sbjct  1866  QKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQ-  1924

Query  99    RPHAD-ELK-AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ  156
               H D E K A  ++  ++L   +     + ++   +  +EL      Y Q+ +EK+  +
Sbjct  1925  --HNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQE  1982

Query  157   LEGLTFQ----MKKNAEELKARISASAEELRQRLAPL---AEDVRGNL----RGNTEGLQ  205
              E L  +    +K+   E   +++   +EL   +      A++V   L    +  T  L 
Sbjct  1983  QEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLL  2042

Query  206   KSLAELGGHLDQQVEEFRRRVEPYGENFN---KALVQQMEQLRQK  247
             K +AE    L +  + +   ++   E      + L  Q+E+L++K
Sbjct  2043  KKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKK  2087


>gi|13432177|sp|P35749|MYH11_HUMAN  Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length=1972

 Score = 45.1 bits (105),  Expect = 5e-05
 Identities = 61/268 (22%), Positives = 113/268 (42%), Gaps = 50/268 (18%)

Query  49    LQKSELT-QQLNALFQDKLGEAEQLRRQLTPYAQRMERV---LRENADSLQASLRPHADE  104
             L+K E + Q+L  L +   G+A     Q+     ++  +   L +  + LQA+L    DE
Sbjct  1043  LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE  1102

Query  105   LKAKID--QNVEELKGRLTPY-------------ADEFKVKIDQTVEELRRSLAPYAQDT  149
             +  K +  + + EL+G ++               A++ K  + + +E L+  L      T
Sbjct  1103  IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST  1162

Query  150   --QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDV----------RGNL  197
               Q++L  + E     +KK  +E      A  +E+RQ+ A   E++          + NL
Sbjct  1163  ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL  1222

Query  198   RGNTEGLQKSLAELGGHL------DQQVEEFRRRVEPY----------GENFNKALVQQM  241
               N + L+K  A+L G L       Q+VE  ++++E            GE     L  ++
Sbjct  1223  DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV  1282

Query  242   EQLRQKLGPHAG---DVEGHLSFLEKDL  266
              +L+ ++    G   + EG    L KD+
Sbjct  1283  HKLQNEVESVTGMLNEAEGKAIKLAKDV  1310


 Score = 40.0 bits (92),  Expect = 0.001
 Identities = 54/247 (21%), Positives = 97/247 (39%), Gaps = 48/247 (19%)

Query  45    AVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRM----ERVLRENAD--------  92
             A +  +  E+  ++ A  +++    +QL+ +    AQ+M    E++  E A         
Sbjct  914   AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK  973

Query  93    -SLQASLRPHADELKAKIDQN----------VEELKGRLTPYADE---------FKVKID  132
              + +A ++   DE+    DQN           E +    T  A+E          K K +
Sbjct  974   VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE  1033

Query  133   QTVEELRRSLAPYAQDTQE--KLNHQLEG-------LTFQMKKNAEELKARISASAEELR  183
               + EL   L    +  QE  KL  +LEG           ++    ELK +++   EEL+
Sbjct  1034  SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ  1093

Query  184   QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF--RRRVEPYGENFNKALVQQM  241
               LA L +++            K + EL GH+    E+    R      E   + L +++
Sbjct  1094  AALARLDDEI-----AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL  1148

Query  242   EQLRQKL  248
             E L+ +L
Sbjct  1149  EALKTEL  1155


 Score = 37.7 bits (86),  Expect = 0.007
 Identities = 58/260 (22%), Positives = 104/260 (40%), Gaps = 34/260 (13%)

Query  37    QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV---LRENADS  93
             QLS++ K+  +     E  ++    FQ ++    Q   +      ++E+    L++  D 
Sbjct  1372  QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD  1431

Query  94    L------QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA----  143
             L      Q  L  + ++ + K DQ + E K   + YADE      +  E+  ++L+    
Sbjct  1432  LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA  1491

Query  144   -PYAQDTQEKLNHQLEGLTFQMK----------KNAEEL---KARISASAEELRQRLAPL  189
                A + +E+L    + L  +M+          KN  EL   K  +    EE++ +L  L
Sbjct  1492  LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL  1551

Query  190   ------AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
                    ED +  L  N + L+          D+Q EE RR+++     +   L  + +Q
Sbjct  1552  EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ  1611

Query  244   LRQKLGPHAGDVEGHLSFLE  263
              R         +EG L  LE
Sbjct  1612  -RALAAAAKKKLEGDLKDLE  1630


 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 39/162 (24%), Positives = 79/162 (48%), Gaps = 12/162 (7%)

Query  38    LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
             +S+  ++A +  Q  +L+ +L A  +    + E  R+QL    + +   L E   ++++ 
Sbjct  1755  MSDRVRKATQ--QAEQLSNEL-ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK  1811

Query  98    LRPHADELKAKIDQNVE--ELKGRLTPYADEFKVKIDQTVEEL------RRSLAPYAQDT  149
              +     L+AKI Q  E  E + R    A +   + D+ ++E+       R +A   ++ 
Sbjct  1812  FKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ  1871

Query  150   QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
              EK N +++ L  Q+++ AEE   RI+A+  +L++ L    E
Sbjct  1872  AEKGNARVKQLKRQLEE-AEEESQRINANRRKLQRELDEATE  1912


 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 34/126 (26%), Positives = 67/126 (53%), Gaps = 23/126 (18%)

Query  103  DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK--LNHQLEGL  160
            +E++AK D+ +++ K R        + K +  ++EL +    ++Q T+EK  L  QL+  
Sbjct  852  EEMQAKEDE-LQKTKER--------QQKAENELKELEQK---HSQLTEEKNLLQEQLQAE  899

Query  161  TFQMKKNAEELKARISASAEELRQRLAPL-----AEDVRGNLRGNTEGLQKSLAELGGHL  215
            T ++   AEE++ R++A  +EL + L  +      E+ RG      +  +K +A+    L
Sbjct  900  T-ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ---QLQAERKKMAQQMLDL  955

Query  216  DQQVEE  221
            ++Q+EE
Sbjct  956  EEQLEE  961


>gi|32470610|sp|Q08378|GOGA3_HUMAN  Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated 
protein of 170 kDa) (GCP170)
Length=1498

 Score = 44.3 bits (103),  Expect = 8e-05
 Identities = 62/260 (23%), Positives = 117/260 (45%), Gaps = 48/260 (18%)

Query  37   QLSNNAKEAVEHLQKSELT-----QQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
            +++++A    + L++ +LT     QQL AL Q+ L     L +QLT      +  L+   
Sbjct  686  RMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHL----DLMKQLT----LTQEALQSRE  737

Query  92   DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF-KVKIDQTVEELRRSLAPYAQDTQ  150
             SL A L+ H DEL+A++     EL+G      D    ++ ++ + E     A   ++  
Sbjct  738  QSLDA-LQTHYDELQARLG----ELQGEAASREDTICLLQNEKIILEAALQAAKSGKEEL  792

Query  151  EKLNHQLEGLTFQMKKNAEELKARI---SASAEELRQRLAPLAEDVRG------------  195
            ++   +LE  T +  +  E+L+  +   S   E L+Q  A L + ++             
Sbjct  793  DRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMV  852

Query  196  -NLRGNTEGLQKSLAELGG---HLDQQVEEFRRRV-EPYGENFN-----KALVQQMEQLR  245
               R +     + ++EL      LD +++E R+ + + +GE          L +++ Q+R
Sbjct  853  EAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVR  912

Query  246  QKLGPHAGDVEGHLSFLEKD  265
            Q    H  D+EGHL   +K+
Sbjct  913  Q----HMADLEGHLQSAQKE  928


 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 44/198 (22%)

Query  37   QLSNNAKEAVEHLQK-SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
            +L   A+   E  ++ SE  ++L      K G+ E L+++     ++M+++  +    LQ
Sbjct  791  ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQ---FLQ  847

Query  96   ASLRPHA------------DELKA---KIDQNVEELKGRLTPYADEFKV------KIDQT  134
              +   A             ELKA   ++D  ++EL+  L     E +       ++ + 
Sbjct  848  QKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHRE  907

Query  135  VEELRRSLAPY------AQDTQEKLNHQLEGLTFQ-------------MKKNAEELKARI  175
            V ++R+ +A        AQ  ++++   L+ L F              +KK  EEL+   
Sbjct  908  VAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEA  967

Query  176  SASAEELRQRLAPLAEDV  193
              +  E +Q++  L  D+
Sbjct  968  RKAITEQKQKMRRLGSDL  985


>gi|13638390|sp|P12882|MYH1_HUMAN  Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin 
heavy chain IIx/d) (MyHC-IIx/d)
Length=1939

 Score = 43.9 bits (102),  Expect = 1e-04
 Identities = 51/207 (24%), Positives = 91/207 (43%), Gaps = 37/207 (17%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI  109
             +K     ++  L ++  G  E + + LT   + ++   ++  D LQA         KAKI
Sbjct  971   EKHATENKVKNLTEEMAGLDETIAK-LTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI  1029

Query  110   --DQNVEELKGRLTPYADEFKVKIDQTVEELRRSL----------APYAQDTQEKLNHQL  157
               +Q V++L+G L     E K+++D  +E  +R L          A   ++ +++L+ +L
Sbjct  1030  KLEQQVDDLEGSLE---QEKKIRMD--LERAKRKLEGDLKLAQESAMDIENDKQQLDEKL  1084

Query  158   -----------------EGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLR  198
                              + L  Q++K  +EL+ARI    EE+    A    AE  R +L 
Sbjct  1085  KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS  1144

Query  199   GNTEGLQKSLAELGGHLDQQVEEFRRR  225
                E + + L E GG    Q+E  ++R
Sbjct  1145  RELEEISERLEEAGGATSAQIEMNKKR  1171


 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 44/159 (27%), Positives = 71/159 (44%), Gaps = 23/159 (14%)

Query  48    HLQ--KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL  105
             HL+  K  L Q +  L Q +L EAEQL  +            ++    L+A +R    E+
Sbjct  1782  HLERMKKNLEQTVKDL-QHRLDEAEQLALKGG----------KKQIQKLEARVRELEGEV  1830

Query  106   KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK  165
             +++  +NVE +KG L  +  + K    QT E+ +  L    QD  +KL  +++    Q +
Sbjct  1831  ESEQKRNVEAVKG-LRKHERKVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAE  1887

Query  166   KNAEELKA------RISASAEELRQRLAPLAEDVRGNLR  198
             +  E+         RI    EE  +R A +AE     LR
Sbjct  1888  EAEEQSNVNLSKFRRIQHELEEAEER-ADIAESQVNKLR  1925


 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 44/217 (20%), Positives = 90/217 (41%), Gaps = 15/217 (6%)

Query  51    KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID  110
             K ++   LN + + +L  A ++  +     +  + +L++    L  +LR   D LK ++ 
Sbjct  1619  KKKMEGDLNEM-EIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQED-LKEQLA  1676

Query  111   QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN--HQLEGLTFQMKKNA  168
               VE     L    +E +  ++QT E  R+       D  E++   H         KK  
Sbjct  1677  M-VERRANLLQAEIEELRATLEQT-ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL  1734

Query  169   EELKARISASAEELRQRLAPLAEDVRGNLRGNT---EGLQKS------LAELGGHLDQQV  219
             E   ++I    E++ Q      E  +  +       E L+K       L  +  +L+Q V
Sbjct  1735  ETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV  1794

Query  220   EEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE  256
             ++ + R++   +   K   +Q+++L  ++    G+VE
Sbjct  1795  KDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE  1831


>gi|3043372|sp|P11055|MYH3_HUMAN  Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic 
myosin heavy chain) (SMHCE)
Length=1940

 Score = 43.9 bits (102),  Expect = 1e-04
 Identities = 62/254 (24%), Positives = 108/254 (42%), Gaps = 46/254 (18%)

Query  38    LSNNAKEAVEHLQKSELTQ-QLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
             L N+ ++  E L+K +    QL +  +D+     Q ++++     R+E  L E  ++ +A
Sbjct  1070  LENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEE-LEEEIEAERA  1128

Query  97    SLRPHADELKAKIDQNVEELKGRL------TPYADEFKVKIDQTVEELRRSLAPYA----  146
             + R   ++ ++   + +EEL  RL      T    E   K +    +LRR L        
Sbjct  1129  T-RAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE  1187

Query  147   ----------QDTQEKLNHQLEGLTF---QMKKNAEELKARI---SASAEELRQRLAPLA  190
                        D+  +L  Q++ L     +++K   E K  I   S+S E + +  A L 
Sbjct  1188  AMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE  1247

Query  191   ------EDVRGNLRGNTEGLQKSLAEL----------GGHLDQQVEEFRRRVEPYGENFN  234
                   ED     RG  E +Q+SL+EL           G L +Q+EE    V     +  
Sbjct  1248  KICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS-K  1306

Query  235   KALVQQMEQLRQKL  248
             +A  QQ E+L+++L
Sbjct  1307  QAFTQQTEELKRQL  1320


>gi|42558938|sp|Q8TD31|CCHCR_HUMAN  Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil 
rod protein) (Putative gene 8 protein) (Pg8)
Length=782

 Score = 43.5 bits (101),  Expect = 1e-04
 Identities = 44/173 (25%), Positives = 81/173 (46%), Gaps = 22/173 (12%)

Query  36   SQLSNNAKEAVEHLQKSELTQQLNA-LFQDKLGEA----EQLRRQLTPYAQRMERVLREN  90
            + +S   ++  E   + +   QL+A L Q ++G A    E  R+QL+  AQ++E+ L++ 
Sbjct  499  TDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQT  558

Query  91   ADSLQASLRPHADELKAKIDQNVEE---LKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ  147
             +SL ASL    +  +    ++ EE   L+  LT   + +   + + V E+   L     
Sbjct  559  QESL-ASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEKVAEVETRLREQLS  617

Query  148  DTQEKLN-------------HQLEGLTFQMKKNAEELKARISASAEELRQRLA  187
            DT+ +LN              Q++    Q K+ ++EL+     + +E  QRLA
Sbjct  618  DTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLA  670


 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 18/105 (17%)

Query  164  MKKNAEELKARISASAEELRQR----LAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQV  219
            ++KN EE   R     + L Q     L    E+   +L    EGL+KSL+ L        
Sbjct  156  VRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLSSL--------  207

Query  220  EEFRRRVEPYGENFNKALVQ-QMEQLRQKLGPHAGDVEGHLSFLE  263
             E RR     GE    A  Q + E LR++L     D+E  ++ +E
Sbjct  208  -ETRRA----GEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVE  247


>gi|3041706|sp|P13533|MYH6_HUMAN  Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha)
Length=1939

 Score = 43.1 bits (100),  Expect = 2e-04
 Identities = 53/214 (24%), Positives = 92/214 (42%), Gaps = 45/214 (21%)

Query  43    KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRP--  100
             K A E+  K+ LT+++  L        +++  +LT   + ++   ++  D LQ       
Sbjct  970   KHATENKVKN-LTEEMAGL--------DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVN  1020

Query  101   HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL-------  153
                + K K++Q V++L+G L     E KV++D  +E  +R L    + TQE +       
Sbjct  1021  SLSKSKVKLEQQVDDLEGSLE---QEKKVRMD--LERAKRKLEGDLKLTQESIMDLENDK  1075

Query  154   -----------------NHQLE---GLTFQMKKNAEELKARISASAEELRQRLAPLA--E  191
                              N ++E    L  Q++K  +E +ARI    EEL       A  E
Sbjct  1076  LQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVE  1135

Query  192   DVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR  225
              +R +L    E + + L E GG    Q+E  ++R
Sbjct  1136  KLRSDLSRELEEISERLEEAGGATSVQIEMNKKR  1169


 Score = 37.4 bits (85),  Expect = 0.009
 Identities = 54/289 (18%), Positives = 118/289 (40%), Gaps = 47/289 (16%)

Query  46    VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPH---A  102
             VE L+     ++  A  + + G+  + + +       +ER L E  + ++ + R H    
Sbjct  1537  VEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVV  1596

Query  103   DELKAKID------QNVEELKGRLTPYADEFKVKIDQT------VEELRRSLAPYAQDTQ  150
             D L+  +D        V  +K ++    +E ++++          ++  +SL    +DTQ
Sbjct  1597  DSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQ  1656

Query  151   EKLNHQLEGLTFQMKKNAEELKAR---ISASAEELR--------------QRLAPLAEDV  193
              +L+  +      +K+N   ++ R   + A  EELR              Q L   +E V
Sbjct  1657  IQLDDAVRA-NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV  1715

Query  194   R------GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
             +       +L    + ++  L +L   +++ V+E R   E   +    A +   E  +++
Sbjct  1716  QLLHSQNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ  1775

Query  248   LGPHAGDVEGHLSFLEKDLRD--KNWGLRLGDRDESGEEGQSRGMQALQ  294
                   D   HL  ++K++    K+   RL + ++   +G  + +Q L+
Sbjct  1776  ------DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE  1818


 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 30/205 (14%)

Query  47    EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             E ++ SE  Q L++     + + +++   LT     +E  ++E  ++ + + +   D   
Sbjct  1707  ELIETSERVQLLHSQNTSLINQKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDAAM  1766

Query  107   AKIDQNVEELKGR--LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM  164
                    EELK     + + +  K  ++QT+++L+  L     D  E++   L+G     
Sbjct  1767  M-----AEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-----DEAEQI--ALKG----G  1810

Query  165   KKNAEELKARISASAEELRQRLAPLAEDVRG---------NLRGNTEGLQKSLAELGGHL  215
             KK  ++L+AR+     EL       AE V+G          L   TE  +K+L  L   +
Sbjct  1811  KKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLV  1870

Query  216   DQ---QVEEFRRRVEPYGENFNKAL  237
             D+   +V+ ++R+ E   E  N  L
Sbjct  1871  DKLQLKVKAYKRQAEEAEEQANTNL  1895


 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 71/241 (29%)

Query  36    SQLSNNAKEAVEHLQKS--------ELTQQLNALFQDKLGEAEQ--LRRQLTPYAQRMER  85
             S LS   +E  E L+++        E+ ++  A FQ    + E+  L+ + T  A R + 
Sbjct  1139  SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH  1198

Query  86    V-----LRENADSLQA---SLRPHADELKAKIDQ-------------NVEELKGRLTPYA  124
                   L E  D+LQ     L     E K ++D              N+E++   L   A
Sbjct  1199  ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA  1258

Query  125   DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
             +E++VK+    EE +RSL  +   T ++   Q E        N E         A +L +
Sbjct  1259  NEYRVKL----EEAQRSLNDF---TTQRAKLQTE--------NGE--------LARQLEE  1295

Query  185   RLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQL  244
             + A +++  RG L                   QQ+E+ +R++E  G+  N AL   ++  
Sbjct  1296  KEALISQLTRGKL----------------SYTQQMEDLKRQLEEEGKAKN-ALAHALQSA  1338

Query  245   R  245
             R
Sbjct  1339  R  1339


 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 33/173 (19%)

Query  36    SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQ--LTPYAQRMERVLRENADS  93
             +QL +  +EAV+  + +E  ++      D    AE+L+++   + + +RM++ + +    
Sbjct  1737  TQLQSEVEEAVQECRNAE--EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD  1794

Query  94    LQ----------------------ASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKI  131
             LQ                      A +R    EL+A+  +N E +KG +       K   
Sbjct  1795  LQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKG-MRKSERRIKELT  1853

Query  132   DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
              QT E+ +  L    QD  +KL  +++      K+ AEE + + + +  + R+
Sbjct  1854  YQTEEDKKNLLR--LQDLVDKLQLKVKA----YKRQAEEAEEQANTNLSKFRK  1900


>gi|27923755|sp|Q9P2M7|CING_HUMAN  Cingulin
Length=1197

 Score = 43.1 bits (100),  Expect = 2e-04
 Identities = 67/260 (25%), Positives = 111/260 (42%), Gaps = 43/260 (16%)

Query  50   QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI  109
            +K+E   +L  L + + GEA+Q  ++L    Q M+R+L +  D            L+  +
Sbjct  392  EKTEECSRLQELLERRKGEAQQSNKEL----QNMKRLLDQGED------------LRHGL  435

Query  110  DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG---LTFQMKK  166
            +  V EL+          K+K  Q  E  +  L     +T+E L   LEG   +  Q++ 
Sbjct  436  ETQVMELQN---------KLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLRL  486

Query  167  NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRV  226
               EL A   A  EE+  R   + E VR   + +TE L++S+ +     D  V E  R+ 
Sbjct  487  RERELTALKGALKEEVASRDQEV-EHVRQQYQRDTEQLRRSMQD--ATQDHAVLEAERQK  543

Query  227  EPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR-DKNWGLRLGDRDESGEEG  285
                     ALV+ +++  ++     G  +      ++DLR  K   L+L    E  EE 
Sbjct  544  -------MSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEE  596

Query  286  QSRGMQALQGFPGRGLEHAK  305
                ++ LQ    R LE A+
Sbjct  597  LGEKIEVLQ----RELEQAR  612


 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 32/133 (24%), Positives = 65/133 (48%), Gaps = 18/133 (13%)

Query  52    SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQ  111
             S+L  Q N L Q++L   E+ +  L    +++ER ++E +  ++   R H ++ K ++  
Sbjct  1042  SQLESQ-NQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDE-RQHVNDQKDQLSL  1099

Query  112   NVEELKGRLTPYADEFKVKIDQTVEELRR--SLAPYAQ---DTQEKLNHQLEGLTFQMKK  166
              V+ LK +           +D+  EE+ R   L   AQ   + Q ++N QL+     ++K
Sbjct  1100  RVKALKRQ-----------VDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEK  1148

Query  167   NAEELKARISASA  179
             ++    +R +A +
Sbjct  1149  DSWRKASRSAAES  1161


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 46/253 (18%)

Query  67   GEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAK--IDQNVEELKGRLTPYA  124
            GEA + R  L    QR+E   ++  ++L AS         AK  ++  +EE +  L    
Sbjct  750  GEAVEAR--LRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLG  807

Query  125  DEFKVKIDQTVEE-------LRRSLAPYAQD------TQEKLNHQLEGLTFQMKKNAEEL  171
             E +  +++ +EE       LRR  A   +       T ++LN +LE +    K+  ++L
Sbjct  808  QEQQT-LNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQL  866

Query  172  KARISASAEELRQRLAPL----------AEDVRGNL-------RGNTEGLQKSLAELG-G  213
            +A++    E+ R+ +A            AE   G L       +   + LQ S AE    
Sbjct  867  QAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTA  926

Query  214  HLDQQVEEFR-RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL-RDKNW  271
             LD+++   R + +E   EN  ++   +  QL+         +E  +S LE +L  +KN 
Sbjct  927  RLDKELLAQRLQGLEQEAENKKRSQDDRARQLK--------GLEEKVSRLETELDEEKNT  978

Query  272  GLRLGDRDESGEE  284
               L DR   G +
Sbjct  979  VELLTDRVNRGRD  991


>gi|13431716|sp|Q9UKX2|MYH2_HUMAN  Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain 
IIa) (MyHC-IIa)
Length=1941

 Score = 42.7 bits (99),  Expect = 2e-04
 Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 8/144 (5%)

Query  87    LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYA  146
             L +  D L+ SL     +L+  +++   +L+G L   A E  + I+   ++L   L    
Sbjct  1033  LEQQVDDLEGSLEQEK-KLRMDLERAKRKLEGDLK-LAQESIMDIENEKQQLDEKLKKKE  1090

Query  147   ---QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLRGNT  201
                 + Q K+  + + L  Q++K  +EL+ARI    EE+    A    AE  R +L    
Sbjct  1091  FEISNLQSKIEDE-QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL  1149

Query  202   EGLQKSLAELGGHLDQQVEEFRRR  225
             E + + L E GG    Q+E  ++R
Sbjct  1150  EEISERLEEAGGATSAQIEMNKKR  1173


 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 32/154 (20%), Positives = 70/154 (45%), Gaps = 7/154 (4%)

Query  38    LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
             +++ A  A E  ++ + +  L  + ++     + L+ +L    Q   +  ++    L+A 
Sbjct  1765  ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR  1824

Query  98    LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
             +R    E++++  +N E +KG L  +    K    QT E+ +  L    QD  +KL  ++
Sbjct  1825  VRELEGEVESEQKRNAEAVKG-LRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQAKV  1881

Query  158   EGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
             +      K+ AEE + + + +  + R+    L E
Sbjct  1882  K----SYKRQAEEAEEQSNTNLAKFRKLQHELEE  1911


>gi|48474907|sp|Q8WYA0|IFT81_HUMAN  Intraflagellar transport 81 (Carnitine deficiency-associated 
protein expressed in ventricle 1) (CDV-1 protein)
Length=676

 Score = 42.7 bits (99),  Expect = 2e-04
 Identities = 42/207 (20%), Positives = 91/207 (43%), Gaps = 15/207 (7%)

Query  53   ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQN  112
            EL +Q +   Q +L   E+ ++ ++ Y+   E + R +A      L+   DE+K +   +
Sbjct  433  ELLKQRHENIQQQLQTMEE-KKGISGYSYTQEELERVSA------LKSEVDEMKGRTLDD  485

Query  113  VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE--KLNHQLEGLTFQMKKNAEE  170
            + E+  +L     E K  +   ++ELR+    Y + TQE  +   Q +     ++ N  +
Sbjct  486  MSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYDSCAAGLESNRSK  545

Query  171  LKARISASAEELRQRLAP------LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR  224
            L+  +    EE  Q  +       + +++   LR  T+ ++  ++       + + E   
Sbjct  546  LEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQQEKRKAIREQYT  605

Query  225  RVEPYGENFNKALVQQMEQLRQKLGPH  251
            +     EN  K L ++ + +R+  GP+
Sbjct  606  KNTAEQENLGKKLREKQKVIRESHGPN  632


>gi|34222508|sp|Q15075|EEA1_HUMAN  Early endosome antigen 1 (Endosome-associated protein p162) (Zinc 
finger FYVE domain-containing protein 2)
Length=1411

 Score = 42.4 bits (98),  Expect = 3e-04
 Identities = 62/266 (23%), Positives = 117/266 (43%), Gaps = 29/266 (10%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQL---TPYAQRMERVLRENADSLQASLR  99
            K   +H ++  L Q   A  ++   + EQ+ RQ+       Q +E +L+++ +++ + L 
Sbjct  485  KTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENI-SLLE  543

Query  100  PHADELKAKIDQNVEE--LKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
               ++L AKI     E  +  +L       + ++ Q  E+L+     + Q  QE L+ Q+
Sbjct  544  KEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ-AQENLHDQV  602

Query  158  EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRG---NLRGNTEGLQKS-------  207
            +     ++  A++    +  S  EL  +L    E V      ++  TE L  +       
Sbjct  603  QEQKAHLRA-AQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQ  661

Query  208  LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR  267
             A+L  HLD      +  ++   +  NK +  Q++Q+  KL     D + H S LE  L+
Sbjct  662  RADLQNHLDTA----QNALQDKQQELNK-ITTQLDQVTAKL----QDKQEHCSQLESHLK  712

Query  268  D-KNWGLRLGDRDESGEEGQSRGMQA  292
            + K   L L  + E   EGQ + ++A
Sbjct  713  EYKEKYLSLEQKTEE-LEGQIKKLEA  737


 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 41/231 (17%), Positives = 97/231 (41%), Gaps = 18/231 (7%)

Query  41    NAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQ-RMERVLRENADSLQASLR  99
             N  + ++ L+ ++ T     L QD   + +QL+ +       + E+ L+E     + S  
Sbjct  1072  NQNKLIQELKTAKAT-----LEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKL  1126

Query  100   PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                +E+K + ++ + +L   L  +  E  +K    +++ ++ L     + Q K +  L+ 
Sbjct  1127  AEIEEIKCRQEKEITKLNEELKSHKLE-SIKEITNLKDAKQLLIQQKLELQGKAD-SLKA  1184

Query  160   LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQV  219
                Q K+N + LK ++    EEL++        +   ++    G++K         ++  
Sbjct  1185  AVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKH--------EENE  1236

Query  220   EEFRRRVEPYGENFN--KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD  268
              +   ++    EN    K   Q  ++   +L     D+ G ++ LE  +++
Sbjct  1237  AKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQN  1287


 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 50/224 (22%), Positives = 100/224 (44%), Gaps = 35/224 (15%)

Query  33    DYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
             D  S++S++ K +    +K    Q+  A   D     ++L+ QL     +ME  L+E   
Sbjct  860   DKLSKVSDSLKNSKSEFEKEN--QKGKAAILDLEKTCKELKHQLQV---QMENTLKEQK-  913

Query  93    SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK  152
                        ELK  +++  E         + + K++++   E+L ++     Q+  EK
Sbjct  914   -----------ELKKSLEKEKEA--------SHQLKLELNSMQEQLIQAQNTLKQN--EK  952

Query  153   LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE--  210
                QL+G   ++K+++E+ K +I A   EL+  +    E      +  T+  Q+  AE  
Sbjct  953   EEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKE  1012

Query  211   ----LGGHLDQQVEEFRR-RVEPYG-ENFNKALVQQMEQLRQKL  248
                 L  + ++  E F++ + + YG E+   A  Q ++ + +KL
Sbjct  1013  KISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKL  1056


 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 34/150 (22%), Positives = 70/150 (46%), Gaps = 11/150 (7%)

Query  42   AKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ-ASLRP  100
            A++ V  L+ S    +LN+   +   +  QL  Q+    + +  +  E A + Q A L+ 
Sbjct  612  AQDRVLSLETS--VNELNSQLNESKEKVSQLDIQIKAKTELL--LSAEAAKTAQRADLQN  667

Query  101  HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE---ELRRSLAPYAQD--TQEKLNH  155
            H D  +  +    +EL  ++T   D+   K+    E   +L   L  Y +   + E+   
Sbjct  668  HLDTAQNALQDKQQELN-KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTE  726

Query  156  QLEGLTFQMKKNAEELKARISASAEELRQR  185
            +LEG   +++ ++ E+KA    + ++L+Q+
Sbjct  727  ELEGQIKKLEADSLEVKASKEQALQDLQQQ  756


>gi|13431724|sp|Q9Y623|MYH4_HUMAN  Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin 
heavy chain IIb) (MyHC-IIb)
Length=1939

 Score = 42.4 bits (98),  Expect = 3e-04
 Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 37/207 (17%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRP--HADELKA  107
             +K     ++  L ++  G  E + + LT   + ++   ++  D LQ          + K 
Sbjct  971   EKHATENKVKNLTEEMAGLDETIAK-LTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKT  1029

Query  108   KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA---PYAQDT-------QEKLNHQL  157
             K++Q V++L+G L     E + K+   +E  +R L      AQ++       +++LN +L
Sbjct  1030  KLEQQVDDLEGSL-----EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL  1084

Query  158   -----------------EGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLR  198
                              + L  Q++K  +EL+ARI    EE+    A    AE  R +L 
Sbjct  1085  KKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS  1144

Query  199   GNTEGLQKSLAELGGHLDQQVEEFRRR  225
                E + + L E GG    Q+E  ++R
Sbjct  1145  RELEEISERLEEAGGATSAQIELNKKR  1171


 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 62/284 (21%), Positives = 108/284 (38%), Gaps = 41/284 (14%)

Query  33    DYFSQLSNNAKEAVEHLQK------SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV  86
             D   +     +EA   LQ+      SE+ Q       D +   E+L       AQR++  
Sbjct  1345  DLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA  1404

Query  87    LR--ENADSLQASLRPHADELKAKIDQNVEEL-----------------KGRLTPYADEF  127
                 E  +S  ASL    ++ K ++   VE+L                 +        E+
Sbjct  1405  EEHVEAVNSKCASL----EKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEW  1460

Query  128   KVKIDQTVEELR------RSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEE  181
             K K ++T  EL       RSL+      +      L+ L   +K+  + L+  IS   E+
Sbjct  1461  KQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLE-TLKRENKNLQQEISDLTEQ  1519

Query  182   LRQRLAPL--AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR---RVEPYGENFNKA  236
             + +    +   E V+  L      LQ SL E    L+ +  +  R    +       ++ 
Sbjct  1520  IAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRK  1579

Query  237   LVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDE  280
             + ++ E+L Q    H   VE   S L+ ++R +N  LR+  + E
Sbjct  1580  IAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKME  1623


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 39/146 (26%), Positives = 67/146 (45%), Gaps = 20/146 (13%)

Query  48    HLQ--KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL  105
             HL+  K  + Q +  L Q +LGEAEQL  +            ++    L+A +R    E+
Sbjct  1782  HLERMKKNMEQTVKDL-QLRLGEAEQLALKGG----------KKQIQKLEARVRELESEV  1830

Query  106   KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK  165
             +++   NVE +KG L  +    K    QT E+ +  L    QD  +KL  +++      K
Sbjct  1831  ESEQKHNVEAVKG-LRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQTKVKA----YK  1883

Query  166   KNAEELKARISASAEELRQRLAPLAE  191
             + AEE + + + +  + R+    L E
Sbjct  1884  RQAEEAEEQSNVNLAKFRKLQHELEE  1909


>gi|76803557|sp|P11532|DMD_HUMAN  Dystrophin
Length=3685

 Score = 42.0 bits (97),  Expect = 4e-04
 Identities = 43/192 (22%), Positives = 82/192 (42%), Gaps = 23/192 (11%)

Query  58    LNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPH---ADELKAKIDQNVE  114
             LN+ +      AE+    L  Y + ME    +N D +   +       DE + K  Q  E
Sbjct  1656  LNSNWIAVTSRAEEWLNLLLEYQKHME-TFDQNVDHITKWIIQADTLLDESEKKKPQQKE  1714

Query  115   ELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE-------KLNHQLEGLTFQMK--  165
             ++  RL    ++ + K+D T ++    +A      ++       +LNH+   ++ ++K  
Sbjct  1715  DVLKRLKAELNDIRPKVDSTRDQAANLMANRGDHCRKLVEPQISELNHRFAAISHRIKTG  1774

Query  166   ------KNAEELKARISASAE----ELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL  215
                   K  E+  + I    E    E++Q +    ED   ++  + EG  K L + G +L
Sbjct  1775  KASIPLKELEQFNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNL  1834

Query  216   DQQVEEFRRRVE  227
              Q++ + R+R E
Sbjct  1835  QQRITDERKREE  1846


 Score = 37.7 bits (86),  Expect = 0.007
 Identities = 58/223 (26%), Positives = 104/223 (46%), Gaps = 28/223 (12%)

Query  38    LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
             LS   KE +     SE++++  + F++  G  ++L  QL  + Q++E    E  + L+  
Sbjct  999   LSTTVKE-MSKKAPSEISRKYQSEFEEIEGRWKKLSSQLVEHCQKLE----EQMNKLR-K  1052

Query  98    LRPHADELK---AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
             ++ H   LK   A++D  ++E    L   ++  K ++ Q      R L    Q  Q  LN
Sbjct  1053  IQNHIQTLKKWMAEVDVFLKEEWPALGD-SEILKKQLKQC-----RLLVSDIQTIQPSLN  1106

Query  155   HQLEGLTFQMKKNAE-ELKARISASAEELR-------QRLAPLAEDVRGNLRGNTEGLQK  206
                EG   ++K  AE E  +R+    +EL        Q++    E ++G L   T  LQK
Sbjct  1107  SVNEGGQ-KIKNEAEPEFASRLETELKELNTQWDHMCQQVYARKEALKGGLE-KTVSLQK  1164

Query  207   SLAELGGHLDQQVEEFRRRVEPY--GENFNKALVQQMEQLRQK  247
              L+E+   + Q  EE+  R   Y   +   KA V++M++ +++
Sbjct  1165  DLSEMHEWMTQAEEEYLERDFEYKTPDELQKA-VEEMKRAKEE  1206


 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 41/223 (18%), Positives = 96/223 (43%), Gaps = 34/223 (15%)

Query  25    DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNAL-FQDKLGEAEQLRRQLTPYAQRM  83
             DQ A +M    +   ++ ++ VE  Q SEL  +  A+  + K G+A    ++L  +   +
Sbjct  1736  DQAANLM----ANRGDHCRKLVEP-QISELNHRFAAISHRIKTGKASIPLKELEQFNSDI  1790

Query  84    ERVLRENADSLQASLRPHADELKAKIDQNVE-----------ELKGRLTPYADEFKVKID  132
             +++L      +Q  +    ++    ++++ E            L+ R+T      ++KI 
Sbjct  1791  QKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIKIK  1850

Query  133   QTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAED  192
             Q + + + +     +  + K   ++    +Q K+ A++L   +    +++ ++LA L E 
Sbjct  1851  QQLLQTKHNALKDLRSQRRKKALEISHQWYQYKRQADDLLKCL----DDIEKKLASLPEP  1906

Query  193   VRGNLRGNTEGLQKSLAELGGHLDQQVEEF---RRRVEPYGEN  232
                         ++ + E+   L ++ EE    RR+ E   E+
Sbjct  1907  RD----------ERKIKEIDRELQKKKEELNAVRRQAEGLSED  1939


>gi|3041707|sp|P13535|MYH8_HUMAN  Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC-perinatal)
Length=1937

 Score = 41.6 bits (96),  Expect = 5e-04
 Identities = 51/207 (24%), Positives = 92/207 (44%), Gaps = 37/207 (17%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPH--ADELKA  107
             +K     ++  L ++  G  E + + L+   + ++   ++  D LQA         + K 
Sbjct  970   EKHATENKVKNLTEEMAGLDETIAK-LSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT  1028

Query  108   KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA---PYAQDT-------QEKLNHQL  157
             K++Q V++L+G L     E K+++D  +E  +R L      AQ++       +++L+ +L
Sbjct  1029  KLEQQVDDLEGSLE---QEKKLRMD--LERAKRKLEGDLKLAQESTMDMENDKQQLDEKL  1083

Query  158   EGLTF-----------------QMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLR  198
             E   F                 Q++K  +EL+ARI    EE+    A    AE  R +L 
Sbjct  1084  EKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLS  1143

Query  199   GNTEGLQKSLAELGGHLDQQVEEFRRR  225
                E + + L E GG    QVE  ++R
Sbjct  1144  RELEEISERLEEAGGATSAQVELNKKR  1170


 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 46/220 (20%), Positives = 96/220 (43%), Gaps = 21/220 (9%)

Query  51    KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD-------  103
             K ++   LN + + +L  A +L  +     +  + +L+E    L  +LR   D       
Sbjct  1618  KKKMEGDLNEM-EIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI  1676

Query  104   -ELKAKIDQ-NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE-KLNHQLEGL  160
              E +A + Q  +EEL   L       K+   + ++   R    + Q+T       +LE  
Sbjct  1677  VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND  1736

Query  161   TFQMKKNAEELKARISASAEELRQRL----APLAEDVRGNLRGNTEGLQKSLAELGGHLD  216
               Q++   EE+  + S +AEE  ++     A +AE+++       +     L  +  +L+
Sbjct  1737  VSQLQSEVEEV-IQESRNAEEKAKKAITDAAMMAEELK-----KEQDTSAHLERMKKNLE  1790

Query  217   QQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE  256
             Q V++ + R++   +   K   +Q+++L  ++    G+VE
Sbjct  1791  QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE  1830


>gi|50400858|sp|Q14980|NUMA1_HUMAN  Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen)
Length=2115

 Score = 40.4 bits (93),  Expect = 0.001
 Identities = 44/199 (22%), Positives = 93/199 (46%), Gaps = 19/199 (9%)

Query  38   LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            L   AKE     ++++L Q L    Q   G   Q+  QL+   ++ E+ L+E A+  +A+
Sbjct  524  LKQQAKE-----KQAQLAQTLQQQEQASQGLRHQVE-QLSSSLKQKEQQLKEVAEKQEAT  577

Query  98   LRPHADELKAKIDQNVEELKGR------LTPYADEFKVKIDQTVEELRRSLAPYAQDTQE  151
             + HA +L    ++    L+ R      L     E   K++   ++L+  +A  A+D+ +
Sbjct  578  RQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ--VANEARDSAQ  635

Query  152  KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE---DVRGNLRGNTEGLQKSL  208
                Q +    ++ +  EEL+A +  + +E  +  A +AE    +R   +  TE  ++ +
Sbjct  636  TSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE--KERV  693

Query  209  AELGGHLDQQVEEFRRRVE  227
            A+    L +Q++  +  ++
Sbjct  694  AQEKDQLQEQLQALKESLK  712


>gi|32469733|sp|Q8IWJ2|GCC2_HUMAN  GRIP and coiled-coil domain-containing protein 2 (Golgi coiled 
coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated 
antigen KW-11)
Length=1583

 Score = 40.4 bits (93),  Expect = 0.001
 Identities = 52/222 (23%), Positives = 99/222 (44%), Gaps = 25/222 (11%)

Query  46    VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRE--NADSLQASLRPHAD  103
             V  +Q +E+T + + + +     AEQ +R L+ Y QR+  +  E   A + QA++    +
Sbjct  1161  VYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFE  1220

Query  104   ELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSLAPYAQDTQEKLNHQLEGL-T  161
               K ++   +++ K +    A+    K + + +E L   L    QD+Q  L   +  L T
Sbjct  1221  SYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQT  1280

Query  162   FQ------MKKNAEELKARISASAEELRQRLAPLAED----------VRGNLRGNTEGLQ  205
              Q      ++++ + L+  +S  A ELR++L  +  +              L    E L+
Sbjct  1281  LQSEHDTLLERHNKMLQETVSKEA-ELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLR  1339

Query  206   KSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
              S  +   HL    EE R+ VE   +  +K +  Q+ QL+ +
Sbjct  1340  NSFRDQVRHLQ---EEHRKTVETLQQQLSK-MEAQLFQLKNE  1377


 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 29/139 (20%), Positives = 59/139 (42%), Gaps = 3/139 (2%)

Query  130  KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
            +I+    EL    + Y++D +  L  QLE       + +E+LK     ++E+  ++L   
Sbjct  29   EIENLKNELMAVRSKYSED-KANLQKQLEEAMNTQLELSEQLK--FQNNSEDNVKKLQEE  85

Query  190  AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG  249
             E +R         LQK L        + V + +  +E   +++ K +    E+L Q   
Sbjct  86   IEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKA  145

Query  250  PHAGDVEGHLSFLEKDLRD  268
             H  +V+  +  +E   ++
Sbjct  146  IHQEEVKELMCQIEASAKE  164


>gi|74739242|sp|Q4ZG46|RBP24_HUMAN  Ran-binding protein 2-like 4 (RanBP2L4)
Length=1583

 Score = 40.4 bits (93),  Expect = 0.001
 Identities = 52/222 (23%), Positives = 99/222 (44%), Gaps = 25/222 (11%)

Query  46    VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRE--NADSLQASLRPHAD  103
             V  +Q +E+T + + + +     AEQ +R L+ Y QR+  +  E   A + QA++    +
Sbjct  1161  VYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFE  1220

Query  104   ELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSLAPYAQDTQEKLNHQLEGL-T  161
               K ++   +++ K +    A+    K + + +E L   L    QD+Q  L   +  L T
Sbjct  1221  SYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQT  1280

Query  162   FQ------MKKNAEELKARISASAEELRQRLAPLAED----------VRGNLRGNTEGLQ  205
              Q      ++++ + L+  +S  A ELR++L  +  +              L    E L+
Sbjct  1281  LQSEHDTLLERHNKMLQETVSKEA-ELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLR  1339

Query  206   KSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
              S  +   HL    EE R+ VE   +  +K +  Q+ QL+ +
Sbjct  1340  NSFRDQVRHLQ---EEHRKTVETLQQQLSK-MEAQLFQLKNE  1377


 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 29/139 (20%), Positives = 59/139 (42%), Gaps = 3/139 (2%)

Query  130  KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
            +I+    EL    + Y++D +  L  QLE       + +E+LK     ++E+  ++L   
Sbjct  29   EIENLKNELMAVRSKYSED-KANLQKQLEEAMNTQLELSEQLK--FQNNSEDNVKKLQEE  85

Query  190  AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG  249
             E +R         LQK L        + V + +  +E   +++ K +    E+L Q   
Sbjct  86   IEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKA  145

Query  250  PHAGDVEGHLSFLEKDLRD  268
             H  +V+  +  +E   ++
Sbjct  146  IHQEEVKELMCQIEASAKE  164


>gi|13123943|sp|O43707|ACTN4_HUMAN  Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross linking 
protein)
Length=911

 Score = 40.0 bits (92),  Expect = 0.001
 Identities = 54/241 (22%), Positives = 97/241 (40%), Gaps = 51/241 (21%)

Query  32   WDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
            WD    L+++ +EA+E  +K     QL A+ Q  L    +  ++  P+   ME  + +  
Sbjct  502  WDALGSLTHSRREALEKTEK-----QLEAIDQLHL----EYAKRAAPFNNWMESAMEDLQ  552

Query  92   DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA--------  143
            D                I   +EE++G ++ + D+FK  +     E    LA        
Sbjct  553  DMF--------------IVHTIEEIEGLISAH-DQFKSTLPDADREREAILAIHKEAQRI  597

Query  144  ------------PYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS--ASAEELRQRLAPL  189
                        PY   T + +N + E +   + K    L    S   S E LR++ A  
Sbjct  598  AESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQ  657

Query  190  AEDVRGNLRGNTEGLQKSLAELGGHLDQQ---VEEFRRRVEPYGENFNKALVQQMEQLRQ  246
            A  V   ++   E + +   E+ G L+ Q   ++++ R +  Y  N +  L++Q  QL Q
Sbjct  658  ANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLD--LLEQQHQLIQ  715

Query  247  K  247
            +
Sbjct  716  E  716


>gi|14195007|sp|Q15149|PLEC1_HUMAN  Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1)
Length=4684

 Score = 39.7 bits (91),  Expect = 0.002
 Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 13/239 (5%)

Query  37    QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
             ++ +NA++ +   +++EL     A  +    E E+ RR+     Q+      E A   +A
Sbjct  2087  RIRSNAEDTLRSKEQAELEA---ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKA  2143

Query  97    SLRPHADELKAKID------QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ  150
             +L    + LKAK++      +  E+   R    A E   K  Q  EE   + A   ++ +
Sbjct  2144  ALE-EVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQ-AEEKAHAFAVQQKEQE  2201

Query  151   EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE  210
              +   Q E       +   E   R +  AEE R +    A   R  +       Q +  +
Sbjct  2202  LQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ  2261

Query  211   LGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
                    Q    + R E   E   +A  +Q   LRQK    A ++E H  F E+ LR K
Sbjct  2262  AQARAQAQAAAEKLRKEAEQEAARRAQAEQ-AALRQKQAADA-EMEKHKKFAEQTLRQK  2318


 Score = 39.3 bits (90),  Expect = 0.002
 Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 19/198 (9%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI  109
             +K  L Q L    Q    +AE+LR  +    +  E+ L++ A  LQ          + ++
Sbjct  2563  EKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEK-LQQEAKLLQLKSEEMQTVQQEQL  2621

Query  110   DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE  169
              Q  + L+       D   ++ ++ +E+ +  L    QD   K             +   
Sbjct  2622  LQETQALQQSFLSEKDSL-LQRERFIEQEKAKLEQLFQDEVAKA------------QQLR  2668

Query  170   ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY  229
             E + R     E+ RQRL    E+ R       EG+++   EL     QQ+E+ RR+ E  
Sbjct  2669  EEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEEL-----QQLEQQRRQQEEL  2723

Query  230   GENFNKALVQQMEQLRQK  247
                 N+ L +Q++ L ++
Sbjct  2724  LAEENQRLREQLQLLEEQ  2741


 Score = 38.9 bits (89),  Expect = 0.003
 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 24/224 (10%)

Query  50    QKSELTQQL-NALFQDKLGEAEQL--RRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
             Q+ E  +QL     Q +L   ++L   R  T   ++  ++L E    LQ           
Sbjct  1829  QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREA--------  1880

Query  107   AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
             A   Q  +EL+  L     E +V +    +    S     + T EK   +LE    + ++
Sbjct  1881  AAATQKRQELEAELAKVRAEMEVLLASKAKAEEES-----RSTSEKSKQRLEAEAGRFRE  1935

Query  167   NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEG-LQKSLAELG--GHLDQQVEEFR  223
              AEE  AR+ A AEE + R   LAE+     R   E  L + LA +G    L  + E   
Sbjct  1936  LAEE-AARLRALAEEAK-RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIAL  1993

Query  224   RRVEPYGENFNKALVQ---QMEQLRQKLGPHAGDVEGHLSFLEK  264
             +  E   E   +       Q  +L ++   H  D+E  L+ L K
Sbjct  1994  KEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRK  2037


 Score = 37.7 bits (86),  Expect = 0.007
 Identities = 60/275 (21%), Positives = 118/275 (42%), Gaps = 49/275 (17%)

Query  25    DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRME  84
             D    ++ +   +L   A EA    Q+S++ ++L ++ + ++ E  +L+ ++   A+   
Sbjct  2336  DHQKNLLDEELQRLKAEATEAAR--QRSQVEEELFSV-RVQMEELSKLKARIE--AENRA  2390

Query  85    RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP  144
              +LR+  D+ Q  L+  A+++K      V E   RL+  A E   ++ Q  EE    LA 
Sbjct  2391  LILRDK-DNTQRFLQEEAEKMK-----QVAEEAARLSVAAQE-AARLRQLAEE---DLAQ  2440

Query  145   YAQDTQEKLNHQLEGLTFQMKKNAE-ELKARISASAEELRQRLAPLAEDVRGNLRGNTEG  203
                  ++ L  +++ +    +  AE EL  +    A+E  +RL    E +   L   T+G
Sbjct  2441  QRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQG  2500

Query  204   LQKSL---------------------AELG---GHLDQQVEEFRRRVEPYGENFNK----  235
              Q++L                     AE+       ++  + FR++ E  GE  ++    
Sbjct  2501  FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELA  2560

Query  236   -----ALVQQMEQLRQKLGPHAGDVEGHLSFLEKD  265
                   LVQ +E  RQ+    A  +   ++ LE++
Sbjct  2561  TQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE  2595


 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 51/232 (21%), Positives = 90/232 (38%), Gaps = 25/232 (10%)

Query  38    LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
             L    + A  H Q     ++     Q ++ E    R +    AQ+ +R ++E    L+ S
Sbjct  1506  LEKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQS  1565

Query  98    LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP-------------  144
                   E++AK  Q     + RL    +   V++     E +R  A              
Sbjct  1566  SEA---EIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEA  1622

Query  145   -----YAQDTQEKLNHQLEGLTFQMKKNAE-ELKARISASAEELR--QRLAPLAEDVRGN  196
                   AQ+  E+L  Q++  + Q K+ AE EL +R+ A AE  R  QR     E++R  
Sbjct  1623  EAQKRQAQEEAERLRRQVQDES-QRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ  1681

Query  197   LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
                    L ++  E    +   +E  +R  E   ++   +  ++  QL + L
Sbjct  1682  AEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSL  1733


 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 35/141 (24%), Positives = 63/141 (44%), Gaps = 24/141 (17%)

Query  49    LQKSELTQQ----LNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE  104
             LQ+    +Q    L  LFQD++ +A+QLR +     Q+ME+  +    S++ + R    E
Sbjct  2640  LQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEA-RRRQHE  2698

Query  105   LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM  164
              +  + +  EEL                Q +E+ RR       +  ++L  QL+ L  Q 
Sbjct  2699  AEEGVRRKQEEL----------------QQLEQQRRQQEELLAEENQRLREQLQLLEEQH  2742

Query  165   K---KNAEELKARISASAEEL  182
             +    ++EE+ A   A+ + L
Sbjct  2743  RAALAHSEEVTASQVAATKTL  2763


>gi|30580364|sp|Q9BV73|CEP2_HUMAN  Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) 
(C-NAP1) (Centrosome protein 250) (Centrosome-associated protein 
CEP250)
Length=2442

 Score = 39.7 bits (91),  Expect = 0.002
 Identities = 53/214 (24%), Positives = 94/214 (43%), Gaps = 20/214 (9%)

Query  43    KEAVEHLQ--KSELTQQLNALFQDKLGEAEQL---RRQLTPYAQRMERVLRENADSLQAS  97
             +E +  LQ  K +L QQL  L + K+GE   L   R Q     Q+  +  RE  +  + S
Sbjct  1742  QEHIHELQELKDQLEQQLQGLHR-KVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQS  1800

Query  98    LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
             L+   DE +  + Q  +EL+      A + + +  Q  EE  +  A   Q   E+ +  L
Sbjct  1801  LQSQLDEAQRALAQRDQELE------ALQQEQQQAQGQEERVKEKADALQGALEQAHMTL  1854

Query  158   EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ  217
             +    +++ + E+ +      A E R+  A   E+V G+LR  +   +K+L  L     +
Sbjct  1855  KERHGELQDHKEQARRLEEELAVEGRRVQA--LEEVLGDLRAESREQEKALLALQQQCAE  1912

Query  218   QVEEFRRRVEPYGENFNKALV------QQMEQLR  245
             Q +E         +++ +A        Q++E LR
Sbjct  1913  QAQEHEVETRALQDSWLQAQAVLKERDQELEALR  1946


 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 10/137 (7%)

Query  54    LTQQLNALFQDKLG---EAEQLRRQLTPYAQRMERVLRENADSLQAS-----LRPHADEL  105
             L ++ ++L QDK+    + E L+ QL         V +E  + L+ +     ++   +  
Sbjct  994   LQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELERE  1053

Query  106   KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK  165
             KA +  ++ E + RL    +   ++  Q +  LR+ +   AQ  Q++L+ Q+E L  ++K
Sbjct  1054  KASLTLSLMEKEQRLLVLQEADSIR-QQELSALRQDMQE-AQGEQKELSAQMELLRQEVK  1111

Query  166   KNAEELKARISASAEEL  182
             +   +  A+ +   EEL
Sbjct  1112  EKEADFLAQEAQLLEEL  1128


>gi|20978868|sp|Q9BY12|ZN291_HUMAN  Zinc finger protein 291
Length=1399

 Score = 39.7 bits (91),  Expect = 0.002
 Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 26/204 (12%)

Query  51   KSELTQQLNALFQDKLGEAEQLR----RQLTPYAQRMERVLRENA--DSLQASLRPHADE  104
            K EL  Q   + ++KL  AE  R    + +   AQ  E  + E A  ++L+A  + H   
Sbjct  582  KEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVL  641

Query  105  LKAK-IDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
             K K  +Q + EL+       +E + + D+ V+E +R+L    Q   E+L          
Sbjct  642  SKLKEYEQRLNELQEERQRRQEEKQAR-DEAVQERKRALEAERQARVEEL---------L  691

Query  164  MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
            MK+  +E      A  E+ RQ      ED     R      ++ LA L     + +EE +
Sbjct  692  MKRKEQE------ARIEQQRQEKEKAREDAA---RERARDREERLAALTAAQQEAMEELQ  742

Query  224  RRVEPYGENFNKALVQQMEQLRQK  247
            ++++   +   +  ++Q+EQ ++K
Sbjct  743  KKIQLKHDESIRRHMEQIEQRKEK  766


>gi|50403702|sp|O95613|PCNT_HUMAN  Pericentrin (Pericentrin B) (Kendrin)
Length=3336

 Score = 39.7 bits (91),  Expect = 0.002
 Identities = 62/261 (23%), Positives = 103/261 (39%), Gaps = 49/261 (18%)

Query  46   VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL  105
            +  +  S   Q+L  L   +  E E LR Q   +A+  E V+              A EL
Sbjct  280  LREMLNSRRAQELALLQSRQQHELELLREQ---HAREKEEVVLRCGQE--------AAEL  328

Query  106  KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE-------  158
            K K+   +E+    +    ++++ + D  +E LR+ L+   Q   E L +Q +       
Sbjct  329  KEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQR  388

Query  159  ---GLTFQMKKNAE----ELKARISASAEELRQRL----APLAEDVR-------------  194
                  FQ K  AE     L++   A+ E+LR+ L        ED+              
Sbjct  389  AELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLE  448

Query  195  -GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL-----VQQMEQLRQK-  247
              NL+ + E L+    E    L  Q++  R   +   E   + L     V+ +EQL+Q+ 
Sbjct  449  LENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQRE  508

Query  248  LGPHAGDVEGHLSFLEKDLRD  268
               H  ++E    + EK LRD
Sbjct  509  KTQHESELEQLRIYFEKKLRD  529


 Score = 35.8 bits (81),  Expect = 0.028
 Identities = 55/239 (23%), Positives = 98/239 (41%), Gaps = 35/239 (14%)

Query  26    QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMER  85
             +V T   D+   L    +EA E  Q+ +  +    L    LG    L        +R+E+
Sbjct  2441  EVPTACPDWRGDLLQVVQEAFEKEQEMQGVELQPRLSGSDLGGHSSL-------LERLEK  2493

Query  86    VLRENADSLQASLR----PHADELKAKID-----------QNVEELKGRLTPYADEFKVK  130
             ++RE  D  + SL     P    L ++I            QN E+L+  L       + +
Sbjct  2494  IIREQGDLQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQ-HLRTALTSAEAR  2552

Query  131   IDQTVEELRR--SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAP  188
               Q   +LRR   L  Y  + ++ +   L+    + ++ A  ++  ++A    +R   + 
Sbjct  2553  GSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVRDLKSD  2612

Query  189   LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
             L E      R  +E L +SL E    + Q+V + R  +    EN  KA +Q++E  + K
Sbjct  2613  LCES-----RQKSEQLSRSLCE----VQQEVLQLRSMLSS-KENELKAALQELESEQGK  2661


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 44/207 (21%), Positives = 88/207 (42%), Gaps = 28/207 (13%)

Query  85    RVLRENADSLQA--SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
             R L E   SL+   +     +ELKA I+ N++E + RL     E   ++ + +E+L+  L
Sbjct  1695  RELEEENTSLKVIYTRSSEIEELKATIE-NLQENQKRLQKEKAEEIEQLHEVIEKLQHEL  1753

Query  143   APYAQDTQEKLNHQLEGLTFQMK----------------KNAEELKARISASAEELRQRL  186
             +       E  + Q   L  ++                 + A E K  +S    +  +R 
Sbjct  1754  SLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEAKEALSRLLADQERRH  1813

Query  187   APLAEDVRGNLRGNTEGLQKSLAELGGHL---DQQVEEFRRRVEPY--GENFNKALVQ--  239
             +   E ++  L+G  E  +  LAEL  ++   + +VE+   R++ +       +A +   
Sbjct  1814  SQALEALQQRLQGAEEAAELQLAELERNVALREAEVEDMASRIQEFEAALKAKEATIAER  1873

Query  240   --QMEQLRQKLGPHAGDVEGHLSFLEK  264
               +++ L Q+   H+ ++E  L  L +
Sbjct  1874  NLEIDALNQRKAAHSAELEAVLLALAR  1900


 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 39/126 (30%), Positives = 58/126 (46%), Gaps = 25/126 (19%)

Query  44   EAVEHLQKSELTQ------QLNALFQDKLGEAEQ-LRRQLTPYAQRMERVLRENA--DSL  94
            E +E L++ E TQ      QL   F+ KL +AE+  +  LT   QR++   RE+A  DS+
Sbjct  499  EDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGA-REDALLDSV  557

Query  95   QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
            +  L     E K +        KGR   + DE +       E  + SL  +  + +E   
Sbjct  558  EVGLSCVGLEEKPE--------KGR-KDHVDELE------PERHKESLPRFQAELEESHR  602

Query  155  HQLEGL  160
            HQLE L
Sbjct  603  HQLEAL  608


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 40/211 (18%)

Query  95    QASLRPHADELKAKIDQNVEELKGRLTPYADEF---KVKIDQTVEELRRSLAPYAQDTQE  151
             +A LR  ++ L  K  + +E++KG L    +E     +K+D    +   SL    ++   
Sbjct  1646  RALLRRESEVLDLK--EQLEKMKGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEE---  1700

Query  152   KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
               N  L+ + +      EELKA I                    NL+ N + LQK  AE 
Sbjct  1701  --NTSLK-VIYTRSSEIEELKATIE-------------------NLQENQKRLQKEKAEE  1738

Query  212   GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL------GPHAGDVEGHLSFLEKD  265
                L + +E+ +  +   G   ++    Q   L+ +L      GP    ++G    LE  
Sbjct  1739  IEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQALQGE---LEAA  1795

Query  266   LRDKNWGLR-LGDRDESGEEGQSRGMQALQG  295
             L  K    R L D++    +      Q LQG
Sbjct  1796  LEAKEALSRLLADQERRHSQALEALQQRLQG  1826


>gi|127234|sp|P26038|MOES_HUMAN  Moesin (Membrane-organizing extension spike protein)
Length=577

 Score = 39.3 bits (90),  Expect = 0.002
 Identities = 54/213 (25%), Positives = 97/213 (45%), Gaps = 37/213 (17%)

Query  68   EAEQLRRQLTP--YAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYAD  125
            E +Q++ Q     + ++MER + EN    +   R  A++ K KI++  EEL  RL    +
Sbjct  301  EVQQMKAQAREEKHQKQMERAMLEN----EKKKREMAEKEKEKIEREKEELMERLKQIEE  356

Query  126  EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR  185
            + K    +  E+ RR+L             +LE    + +  AE+L A+    AEE ++ 
Sbjct  357  QTKKAQQELEEQTRRAL-------------ELEQERKRAQSEAEKL-AKERQEAEEAKEA  402

Query  186  LAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNK--ALVQQ-ME  242
            L   + D     +   E L   +AEL   +  Q+E  R++ E     + +   +VQ+ +E
Sbjct  403  LLQASRD----QKKTQEQLALEMAELTARI-SQLEMARQKKESEAVEWQQKAQMVQEDLE  457

Query  243  QLRQKL-----GPHAGDVEGHLSFLEKDLRDKN  270
            + R +L      PH  +   +    E+D +D+N
Sbjct  458  KTRAELKTAMSTPHVAEPAEN----EQDEQDEN  486


>gi|14194461|sp|Q99996|AKAP9_HUMAN  A-kinase anchor protein 9 (Protein kinase A-anchoring protein 
9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase 
anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 
120-like protein) (Hyperion protein) (Yotiao protein) (Centrosome- 
and Golgi-localized PKN-associated protein) (CG-NAP)
Length=3911

 Score = 39.3 bits (90),  Expect = 0.002
 Identities = 53/249 (21%), Positives = 106/249 (42%), Gaps = 24/249 (9%)

Query  50    QKSELTQQLNAL--FQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKA  107
             QK E T+ L      +++L E  + R QL     + E V+   AD             K 
Sbjct  1897  QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADE------------KT  1944

Query  108   KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN  167
               ++ ++E K  +    ++  +     ++EL        Q+ +E L+ Q E     MK  
Sbjct  1945  LFERQIQE-KTDIIDRLEQELLCASNRLQELEAE-QQQIQEERELLSRQKEA----MKAE  1998

Query  168   AEELKARISASAEELRQRLAPL---AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR  224
             A  ++ ++    E+L +    +   AE VR +L+   + L+  + E      +  +E   
Sbjct  1999  AGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT  2058

Query  225   RVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGEE  284
              +    +  N+AL +Q+E++R+ L   A D E      +++++     L++  R +   E
Sbjct  2059  ELMDLRQQ-NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISE  2117

Query  285   GQSRGMQAL  293
              Q+R ++ L
Sbjct  2118  HQTREVEQL  2126


 Score = 35.8 bits (81),  Expect = 0.028
 Identities = 54/248 (21%), Positives = 105/248 (42%), Gaps = 24/248 (9%)

Query  53    ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA-------DSLQASLRPHADEL  105
             EL Q+ N    D   + + L +QL    ++M + L E A       D  Q  ++    +L
Sbjct  2051  ELEQEKNTELMDLRQQNQALEKQL----EKMRKFLDEQAIDREHERDVFQQEIQKLEQQL  2106

Query  106   KA--KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
             K   +     E     +   A+  K K D+   EL  S     +D QE+ N ++E L F+
Sbjct  2107  KVVPRFQPISEHQTREVEQLANHLKEKTDKC-SELLLSKEQLQRDIQER-NEEIEKLEFR  2164

Query  164   MKKNAEEL--KARISASAEELRQRLAPLAE---DVRGNLRGNTEGLQKSLAELGGHLDQQ  218
             +++  + L   A      E+ +   A  A+    +   L+   + + +   E+  +L++Q
Sbjct  2165  VRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEIT-NLEEQ  2223

Query  219   VEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDR  278
             +E+FR  +E   E   + L  Q+E  +++      ++E      + D+  +  GL + + 
Sbjct  2224  LEQFREELENKNEEVQQ-LHMQLEIQKKESTTRLQELEQENKLFKDDM--EKLGLAIKES  2280

Query  279   DESGEEGQ  286
             D    + Q
Sbjct  2281  DAMSTQDQ  2288


 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 52/218 (23%), Positives = 87/218 (39%), Gaps = 25/218 (11%)

Query  37    QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
             QL    KE+   LQ+ E   Q N LF+D +        +L    +  + +  ++   L  
Sbjct  2244  QLEIQKKESTTRLQELE---QENKLFKDDM-------EKLGLAIKESDAMSTQDQHVLFG  2293

Query  97    SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ  156
                    E + +IDQ    L  ++T    + K+  D  V E +  L    +   E L   
Sbjct  2294  KFAQIIQEKEVEIDQ----LNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSD  2349

Query  157   LEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG---  213
              E     +K+N EE   +++   E+L+Q LA + +    N    +E       +L     
Sbjct  2350  QE----CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIA  2405

Query  214   ---HLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
                 L+QQVE     +  + +N  K    +M QL Q+L
Sbjct  2406  EKLALEQQVETANEEM-TFMKNVLKETNFKMNQLTQEL  2442


>gi|74713839|sp|Q86SQ7|SDCG8_HUMAN  Serologically defined colon cancer antigen 8 (Centrosomal colon 
cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8)
Length=713

 Score = 39.3 bits (90),  Expect = 0.002
 Identities = 44/223 (19%), Positives = 97/223 (43%), Gaps = 26/223 (11%)

Query  50   QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRE-------NADSLQASLRPHA  102
            Q  +++++ N      L + +QLR++L   A+R+E+ L           D ++  +    
Sbjct  342  QVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKER  401

Query  103  DELKAK---IDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE---KLNHQ  156
            + + +K   + QN+ +L+ ++     E K+     +EE++  LA    D  +   ++ +Q
Sbjct  402  EYMGSKMLILSQNIAQLEAQVEKVTKE-KISAINQLEEIQSQLASREMDVTKVCGEMRYQ  460

Query  157  LEGLTF---QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS------  207
            L        + +K   E +A+ +   E   Q +  L  ++  + +   +  QK+      
Sbjct  461  LNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREE  520

Query  208  ---LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
               L EL G  + Q+   R+  +   ++F+K    Q  Q +Q+
Sbjct  521  CLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQR  563


>gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN  Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest 
deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint 
MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 
181)
Length=718

 Score = 38.9 bits (89),  Expect = 0.003
 Identities = 68/290 (23%), Positives = 118/290 (40%), Gaps = 40/290 (13%)

Query  47   EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA------SLRP  100
            E L +    Q+  A  ++K+ E  +  RQ         + LRE  DSL        +L+ 
Sbjct  105  ELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKG  164

Query  101  HADELKAKIDQNVEELKGRLTPYADEFKVKID----------QTVEELRRSLAPYA----  146
               EL+  +      +K RL     E + ++D          Q ++EL+ S    A    
Sbjct  165  RISELQWSVMDQEMRVK-RLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQ  223

Query  147  --QDTQEKLNHQLEGLTFQMKKNAEELK-ARISASAEELRQRLAPLAE--DVRGNLRGNT  201
              +D ++KL+ Q +         +E ++  R+    ++LR+  A L E  +  G L+   
Sbjct  224  QIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEEL  283

Query  202  EGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF  261
            EGLQ+ L        ++++E    +E   E    A +Q  E+L Q +G      E    F
Sbjct  284  EGLQRKLGR-----QEKMQETLVGLELENERL-LAKLQSWERLDQTMGLSIRTPEDLSRF  337

Query  262  L------EKDLRDKNWGLRLGDRDESGEEGQSRGMQALQGFPGRGLEHAK  305
            +      E  L+DKN  +    R    E+ + +  + L+   G+ LE  K
Sbjct  338  VVELQQRELALKDKNSAVTSSAR--GLEKARQQLQEELRQVSGQLLEERK  385


>gi|37537846|sp|Q9H8L6|MMRN2_HUMAN  Multimerin-2 precursor (EMILIN-3) (Elastin microfibril interface 
located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 
p125/p140 subunit)
Length=949

 Score = 38.9 bits (89),  Expect = 0.003
 Identities = 47/227 (20%), Positives = 90/227 (39%), Gaps = 19/227 (8%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD-SLQASLRPH  101
            +E  EHL   +L   ++ +     G  + L   LT       +   E  D SL+  L PH
Sbjct  174  QEQQEHLL-GDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPH  232

Query  102  ADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT  161
             D            L+   +P    F   +    + +R +L+   +  ++ ++   +   
Sbjct  233  VDTF----------LQVHFSPIWRSFNQSLHSLTQAIR-NLSLDVEANRQAISRVQDSAV  281

Query  162  FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE  221
               + + +EL A+  A  +E  QR+  L +DV   L      L +S++EL   +D +++ 
Sbjct  282  --ARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKR  339

Query  222  FRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD  268
              +  E  G N +  L       R    P    ++  L  L+++L +
Sbjct  340  LHKAQEAPGTNGSLVLATPGAGAR----PEPDSLQARLGQLQRNLSE  382


 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 40/187 (21%), Positives = 75/187 (40%), Gaps = 25/187 (13%)

Query  63   QDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK-------------AKI  109
            Q +LG+ ++   +L     R E  L+   + ++A+L  H DE+K             +K+
Sbjct  370  QARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKV  429

Query  110  DQNVEELKGRLTPYAD------EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
            ++ VEEL+   T   +      E  + +++  EE+ R L       Q       + + + 
Sbjct  430  ERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYV  489

Query  164  MKKNAEELKARISASAEELRQRLAPLAE-----DVRGNLRGNT-EGLQKSLAELGGHLDQ  217
               N ++L   +    E  R     L E     D R  L G++ + LQ ++  +   +D 
Sbjct  490  KDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDA  549

Query  218  QVEEFRR  224
               E  R
Sbjct  550  HKAEGER  556


>gi|30912698|sp|Q8NB25|CF060_HUMAN  Hypothetical protein C6orf60
Length=1020

 Score = 38.9 bits (89),  Expect = 0.003
 Identities = 48/235 (20%), Positives = 100/235 (42%), Gaps = 22/235 (9%)

Query  40   NNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLR  99
            N A + + HLQ       +    +  LG AE L   L    +R++  L    DSL+ + +
Sbjct  426  NTANQEIGHLQ------DMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKET-K  478

Query  100  PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                 ++ +++Q  ++ +  +    +E K+K+D+   +L        +    KL  +L  
Sbjct  479  DALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRL  538

Query  160  LTFQMKKNAE----ELKARISASA--------EELRQRLAPLAEDVRGNLRGNTEGLQKS  207
               + KK+A     +LK R   +A        E+L  +++ L +++   L  +   LQ+ 
Sbjct  539  QHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQL  598

Query  208  LAEL---GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL  259
             A+       L Q++EE   + +   ++  +A V   + + ++       +E HL
Sbjct  599  QAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL  653


 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 29/137 (21%), Positives = 57/137 (41%), Gaps = 0/137 (0%)

Query  113  VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK  172
            +EE +  L         +  Q + EL + +    +  QE    +L+ L  ++++   +L 
Sbjct  297  LEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLN  356

Query  173  ARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGEN  232
               S + EEL  +     E V  N   + + LQ  L E        +EE + +++   EN
Sbjct  357  EAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELEN  416

Query  233  FNKALVQQMEQLRQKLG  249
              + L  ++    Q++G
Sbjct  417  LKEVLEDKLNTANQEIG  433


>gi|77416379|sp|Q9UPN4|AZI1_HUMAN  5-azacytidine-induced protein 1 (Pre-acrosome localization protein 
1) (Centrosomal protein of 131 kDa) (Cep131 protein)
Length=1083

 Score = 38.9 bits (89),  Expect = 0.003
 Identities = 60/269 (22%), Positives = 109/269 (40%), Gaps = 23/269 (8%)

Query  46   VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL  105
            ++ L ++EL Q      Q  L +AE+LR QL    + + +  RE A   +   + H ++ 
Sbjct  729  LKSLHEAELLQSDERASQRCLRQAEELREQLEREKEALGQQERERA---RQRFQQHLEQE  785

Query  106  KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK  165
            +  + Q     + RL     E + ++ Q     R  L    Q  +E  +     L  + +
Sbjct  786  QWALQQQ----RQRLYSEVAEERERLGQQAARQRAELEELRQQLEESSSALTRALRAEFE  841

Query  166  KNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL-----QKSLAELGGHLDQQVE  220
            K  EE + R       L+Q+L    +          E       Q+   E+    D+++E
Sbjct  842  KGREEQERRHQMELNTLKQQLELERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIE  901

Query  221  EFRRRVEP----YGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLG  276
                R+E       E   KA   ++++LR K      ++E      E+ L+++   L+ G
Sbjct  902  LVIHRLEADMALAKEESEKAAESRIKRLRDKYEAELSELEQS----ERKLQERCSELK-G  956

Query  277  DRDESGEEGQSRGMQALQGFPGRGLEHAK  305
               E+  EG++  +Q L     R LE A+
Sbjct  957  QLGEA--EGENLRLQGLVRQKERALEDAQ  983


 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 44/199 (22%), Positives = 88/199 (44%), Gaps = 18/199 (9%)

Query  43    KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQ---LTPYAQRMERVLRENADSLQASL-  98
             +E    ++ + L QQL    + +  EA + R++   L    Q +   +R+  D     + 
Sbjct  847   QERRHQMELNTLKQQLE--LERQAWEAGRTRKEEAWLLNREQELREEIRKGRDKEIELVI  904

Query  99    -RPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL----  153
              R  AD   AK +++ +  + R+    D+++ ++ + +E+  R L     + + +L    
Sbjct  905   HRLEADMALAK-EESEKAAESRIKRLRDKYEAELSE-LEQSERKLQERCSELKGQLGEAE  962

Query  154   --NHQLEGLTFQMKKNAEELKA---RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL  208
               N +L+GL  Q ++  E+ +A   ++S+    L Q +    ED        T   +  L
Sbjct  963   GENLRLQGLVRQKERALEDAQAVNEQLSSERSNLAQVIRQEFEDRLAASEEETRQAKAEL  1022

Query  209   AELGGHLDQQVEEFRRRVE  227
             A L      ++EE  RRV+
Sbjct  1023  ATLQARQQLELEEVHRRVK  1041


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 28/120 (23%), Positives = 55/120 (45%), Gaps = 22/120 (18%)

Query  150  QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLA  209
            Q++L+ Q EG   +      EL + +S S   L+  +               E  ++++ 
Sbjct  544  QDQLDSQQEGWVPEAGPGPLELGSEVSTSVMRLKLEV---------------EEKKQAML  588

Query  210  ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
             L   L QQ +   RRV+       KAL +Q+++ R+    +   ++ HL+F+++ + DK
Sbjct  589  LLQRALAQQRDLTARRVK----ETEKALSRQLQRQREH---YEATIQRHLAFIDQLIEDK  641


>gi|1345731|sp|P49454|CENPF_HUMAN  CENP-F kinetochore protein (Centromere protein F) (Mitosin) (AH 
antigen)
Length=3210

 Score = 38.5 bits (88),  Expect = 0.004
 Identities = 56/258 (21%), Positives = 109/258 (42%), Gaps = 27/258 (10%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEA-EQLRRQLTPYAQRMERVLRENADSLQ  95
            QL NN +E  + L ++E   Q + + +++L  + E+++++        E+  RE    L+
Sbjct  448  QLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCH-LE  506

Query  96   ASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNH  155
            A L+            N+++   +   +A+E K K       LR        D QEK+N 
Sbjct  507  AELK------------NIKQCLNQSQNFAEEMKAKNTSQETMLR--------DLQEKINQ  546

Query  156  QLEGLTFQ-MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
            Q   LT + +K    +L+ +   S + L++R   + E +   L   TE   K+L      
Sbjct  547  QENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI-EQLNDKL-SKTEKESKALLSALEL  604

Query  215  LDQQVEEFRRRVEPYG--ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWG  272
              ++ EE +     +   ++ N+ L+ QME  ++ L      +E  L   +    + N  
Sbjct  605  KKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNER  664

Query  273  LRLGDRDESGEEGQSRGM  290
            +R  + D      + R +
Sbjct  665  VRTLEMDRENLSVEIRNL  682


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 42/161 (26%), Positives = 68/161 (42%), Gaps = 17/161 (10%)

Query  148   DTQEKLNHQLEGLTFQMKKNAEELKARIS----------ASAEELRQRLAPLAEDVRGNL  197
             DT  K    L+ L+ +MK+  +EL++  S          A  +E  + L  L+ DV   L
Sbjct  2064  DTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELL  2123

Query  198   RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNK---ALVQQMEQLRQKLGPHAGD  254
             +  T  LQ+ L  L     Q +   +  +E      NK    LV++ E L+ +L     +
Sbjct  2124  KDKTH-LQEKLQSLEKD-SQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE  2181

Query  255   VEGHLSFLEKDLRDK-NWGLRLGDRDESGEEGQSRGMQALQ  294
                    LE  L +K  + LRL    E   +   RG++ L+
Sbjct  2182  KLNVSKALEAALVEKGEFALRLSSTQEEVHQ-LRRGIEKLR  2221


>gi|730299|sp|P41219|PERI_HUMAN  Peripherin
Length=471

 Score = 38.5 bits (88),  Expect = 0.004
 Identities = 59/284 (20%), Positives = 119/284 (41%), Gaps = 55/284 (19%)

Query  33   DYFSQLSNNAKEAVE-------HLQKSELTQQLNALFQDKLGEA--------EQLRRQLT  77
            ++ +  SN  +E  E        ++K    +Q NA  + +L +A        +QL +Q  
Sbjct  89   EFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQEL  148

Query  78   PYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEE  137
               +R   +L    D +Q      A++L A + Q +EE + R    A+   V   + V++
Sbjct  149  RELRRELELLGRERDRVQVERDGLAEDLAA-LKQRLEE-ETRKREDAEHNLVLFRKDVDD  206

Query  138  LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK-ARISASAEELRQ---------RLA  187
               S      + + K+   ++ + F  K + EEL+  ++S  +++++Q          L 
Sbjct  207  ATLSRL----ELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELT  262

Query  188  PLAEDVRG--------NLRGNTEGLQKSLAELGGHLD----------QQVEEFRRRVEPY  229
                D+R         NL+   E  +   A+L    +          Q++ E RR+++  
Sbjct  263  AALRDIRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSL  322

Query  230  G------ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR  267
                      N+AL++Q+ +L ++    AG  +   + LE++LR
Sbjct  323  TCEVDGLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELR  366


>gi|464541|sp|P35241|RADI_HUMAN  Radixin
Length=583

 Score = 38.5 bits (88),  Expect = 0.004
 Identities = 59/237 (24%), Positives = 97/237 (40%), Gaps = 36/237 (15%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQD-------------KLGEAEQLRRQLTPYAQRM  83
            +++   KE +E  +K EL ++L  + +              K  E +Q R++    A+R+
Sbjct  331  EIAEKEKERIER-EKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERL  389

Query  84   ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA  143
            E+  R   ++  A  +  AD++K     N E+L   L     EF  KI   +EE ++   
Sbjct  390  EKERRAAEEAKSAIAKQAADQMK-----NQEQLAAELA----EFTAKI-ALLEEAKKKKE  439

Query  144  PYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEG  203
              A + Q K     E L    +K  EELK  +SA        + P  E+       + E 
Sbjct  440  EEATEWQHKAFAAQEDL----EKTKEELKTVMSAPPPPPPPPVIPPTENEHDE---HDEN  492

Query  204  LQKSLAELG--GHLDQQVEEFRRRVEPYGENFNK---ALVQQMEQLRQKLGPHAGDV  255
              ++ AEL   G ++ + EE R       E   K   AL  ++ Q R +      DV
Sbjct  493  NAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDV  549


>gi|27923959|sp|Q03001|BPA1_HUMAN  Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8 (230 kDa bullous 
pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) 
(Dystonia musculorum protein) (Dystonin)
Length=3214

 Score = 38.5 bits (88),  Expect = 0.004
 Identities = 53/233 (22%), Positives = 98/233 (42%), Gaps = 37/233 (15%)

Query  43    KEAVEH------LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
             KE  EH      LQ+ + T   N+    K+ E E++  +L     R+E  L +  ++ + 
Sbjct  1676  KETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAEN  1735

Query  97    SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ  156
              LR        K  +NVE++  +        K++ +   ++ RR L    ++ +E    +
Sbjct  1736  ELR--------KQQRNVEDISLQ--------KIRAESEAKQYRRELETIVRE-KEAAERE  1778

Query  157   LEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLD  216
             LE +  Q+   AE  +A +  +    R +L       R  L  + +    SL +L    +
Sbjct  1779  LERVR-QLTIEAEAKRAAVEENLLNFRNQLEE-NTFTRRTLEDHLKRKDLSLNDLEQQKN  1836

Query  217   QQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
             + +EE RR+ +   E     L++QME+          D+       EK L++K
Sbjct  1837  KLMEELRRKRD--NEEELLKLIKQMEK----------DLAFQKQVAEKQLKEK  1877


 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 54/258 (20%), Positives = 102/258 (39%), Gaps = 46/258 (17%)

Query  23    SADQVATVMWDYFSQLSNNAKEAVEHLQKS---------ELTQQLNALFQDKLGEAEQLR  73
             S   V  +  ++  Q +   K+ V+ L  +         ELT +LNAL  +K    E+ R
Sbjct  1910  SCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKAR  1969

Query  74    -----RQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK  128
                     T    R  ++  E  D  +        EL  +++Q   + +  +   +D  K
Sbjct  1970  LLKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKK  2029

Query  129   V----------------KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ--------M  164
             +                K+ + V+ + R+ A  A+   + LN Q+     +         
Sbjct  2030  IKRNYQLELESLNHEKGKLQREVDRITRAHA-VAEKNIQHLNSQIHSFRDEKELERLQIC  2088

Query  165   KKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR  224
             ++ ++ LK +   S E+L Q +    E+    ++   E L+KS  E    L Q+VEE  R
Sbjct  2089  QRKSDHLKEQFEKSHEQLLQNIKAEKEN-NDKIQRLNEELEKS-NECAEMLKQKVEELTR  2146

Query  225   RVEPYGENFNKALVQQME  242
             +      N  K ++Q+++
Sbjct  2147  Q-----NNETKLMMQRIQ  2159


>gi|26400672|sp|Q96F44|TRI11_HUMAN  Tripartite motif protein 11 (RING finger protein 92) (BIA1 protein)
Length=468

 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 51/219 (23%), Positives = 87/219 (39%), Gaps = 30/219 (13%)

Query  53   ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQN  112
            EL+ Q N      L +  ++ R+L P +   + V   + + L A        L A  +++
Sbjct  58   ELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERS  117

Query  113  VEELKGRLTPY---ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE  169
             E    R+ P    A++ K K+++++E LR+ +               + L FQ      
Sbjct  118  GEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQ--------------DALLFQ------  157

Query  170  ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY  229
                   A A+E       + E  R N+ G  E L++ LAE    L Q++EE    V P 
Sbjct  158  -------AQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPR  210

Query  230  GENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD  268
                   L QQ   L + +    G  +     L +D++D
Sbjct  211  LREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIKD  249


>gi|74759012|sp|Q7L7X3|TAOK1_HUMAN  Serine/threonine-protein kinase TAO1 (Thousand and one amino 
acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken 
homolog B) (hKFC-B)
Length=1001

 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 35/158 (22%), Positives = 73/158 (46%), Gaps = 29/158 (18%)

Query  43   KEAVEHLQKSELTQQLNA----------------------LFQDKLGEAEQLRRQLTPYA  80
            ++  EH Q SEL +Q++                       + + +L   + L  Q   +A
Sbjct  449  RQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFA  508

Query  81   QRMERVLRENADSLQASLRPHADELKAKIDQNVE-----ELKGRLTPYADEFKVKIDQTV  135
              ME++++++  +++   +  ++E K K  Q+++     EL   L     E+K++ +Q  
Sbjct  509  AEMEKLIKKHQAAMEKEAKVMSNEEK-KFQQHIQAQQKKELNSFLESQKREYKLRKEQLK  567

Query  136  EELRRSLAPYAQDTQEKLNHQLEGLT-FQMKKNAEELK  172
            EEL  + +   ++ QE L+ Q E +  FQ ++ A  L+
Sbjct  568  EELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLR  605


>gi|29337005|sp|Q9UQE7|SMC3_HUMAN  Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 
6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) 
(Basement membrane-associated chondroitin proteoglycan)
Length=1217

 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 52/242 (21%), Positives = 102/242 (42%), Gaps = 43/242 (17%)

Query  53   ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID--  110
            E  ++  +L ++  G+ E++   L    +R+  +  E  +  Q       D+++  ++  
Sbjct  170  ERKEESISLMKETEGKREKINELLKYIEERLHTLEEEKEELAQYQ---KWDKMRRALEYT  226

Query  111  ---QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN  167
               Q + E + +L    DE   K  +T  E  R L    QD ++K+          +++ 
Sbjct  227  IYNQELNETRAKL----DELSAK-RETSGEKSRQLRDAQQDARDKME--------DIERQ  273

Query  168  AEELKARISASAEELRQ-------------RLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
              ELK +ISA  EE  Q             +L   A+D++  L GN+E  ++ L E    
Sbjct  274  VRELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKE-RQK  332

Query  215  LDQQVEEFRRRVEPYGENFN-------KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR  267
            L +++EE ++ +      FN       + + +  +  +++   +A    G   F  K+ R
Sbjct  333  LLEKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGS-QFTSKEER  391

Query  268  DK  269
            DK
Sbjct  392  DK  393


>gi|13431717|sp|Q9UKX3|MYH13_HUMAN  Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) 
(MyHC-eo)
Length=1938

 Score = 38.1 bits (87),  Expect = 0.006
 Identities = 37/144 (25%), Positives = 65/144 (45%), Gaps = 8/144 (5%)

Query  87    LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYAD---EFKVKIDQTVEELRRSLA  143
             L +  D L+ SL     +L+A +++   +L+G L    +   + + +  Q  E+L++   
Sbjct  1031  LEQQTDDLEGSLEQEK-KLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEF  1089

Query  144   PYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL--RQRLAPLAEDVRGNLRGNT  201
               +Q      + Q+  L FQ  K  +EL+ARI    EE+     L    E  R +L    
Sbjct  1090  ELSQLQARIDDEQVHSLQFQ--KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLAREL  1147

Query  202   EGLQKSLAELGGHLDQQVEEFRRR  225
             E + + L E  G    Q+E  ++R
Sbjct  1148  EEISERLEEASGATSAQIEMNKKR  1171


>gi|32470611|sp|Q08379|GOGA2_HUMAN  Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) 
(Gm130 autoantigen) (Golgin-95)
Length=990

 Score = 37.7 bits (86),  Expect = 0.007
 Identities = 55/257 (21%), Positives = 106/257 (41%), Gaps = 25/257 (9%)

Query  52   SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL-----K  106
            SE+ QQL A       EAE LR++L   A +++  +++N + L    R   + L      
Sbjct  447  SEVEQQLQA-------EAEHLRKELEGLAGQLQAQVQDN-EGLSRLNREQEERLLELERA  498

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTV---EELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
            A++     E + ++       +  I + +    EL+  LA       +  N  +E +T  
Sbjct  499  AELWGEQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENME-ITSA  557

Query  164  MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
            + ++ + +K  +     EL+++L+ L E V    +   + LQ+   +  GHL Q V  ++
Sbjct  558  L-QSEQHVKRELGKKLGELQEKLSELKETVELKSQ-EAQSLQQQRDQYLGHLQQYVAAYQ  615

Query  224  RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGE  283
            +         N+ L+Q   QL  +L       +       ++L++    L    +    +
Sbjct  616  QLTSEKEVLHNQLLLQ--TQLVDQLQQQEAQGKAVAEMARQELQETQERLEAATQ----Q  669

Query  284  EGQSRGMQALQGFPGRG  300
              Q R   +L   PG G
Sbjct  670  NQQLRAQLSLMAHPGEG  686


>gi|12643547|sp|O15519|CFLAR_HUMAN  CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like 
inhibitory protein) (c-FLIP) (Caspase-eight-related 
protein) (Casper) (Caspase-like apoptosis regulatory protein) 
(CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase 
homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like 
antiapoptotic molecule 1) (Flame-1) (Usurpin) [Contains: CASP8 
and FADD-like apoptosis regulator subunit p43; CASP8 and 
FADD-like apoptosis regulator subunit p12]
Length=480

 Score = 37.7 bits (86),  Expect = 0.007
 Identities = 42/178 (23%), Positives = 85/178 (47%), Gaps = 10/178 (5%)

Query  44   EAVEHLQKSELTQQLNALFQDKLGEAEQLRRQ----LTPYAQRMERVLRENADSLQASLR  99
            E  E L KS+++  L  L +D +G  +  + +    L    +++  V  +  D L+  L+
Sbjct  99   EIGEDLDKSDVSS-LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLK  157

Query  100  P-HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY-AQDTQEKLNHQL  157
              H  +LK KI +  + ++G  T Y +  +  I +++++   +   +  +  +++L  QL
Sbjct  158  NIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNNFRLHNGRSKEQRLKEQL  217

Query  158  EGLTFQMKKNAEELKARISASAEELRQRL--APLAEDVRGNLRGN-TEGLQKSLAELG  212
                  +KK+ +E +A +  S  E R ++   PL   +  +  GN TE L+ +   LG
Sbjct  218  GAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIIDCIGNETELLRDTFTSLG  275


>gi|78099806|sp|Q9BYV6|TRI55_HUMAN  Tripartite motif-containing 55 (Muscle-specific RING finger protein 
2) (MuRF2) (MURF-2) (RING finger protein 29)
Length=548

 Score = 37.4 bits (85),  Expect = 0.009
 Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 27/222 (12%)

Query  36   SQLSNNAKEAVE--HLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADS  93
            SQL +  K   E    QK EL ++ + L+    G  E+ + ++T   Q + R   E  + 
Sbjct  191  SQLEDTCKTIEECCRKQKQELCEKFDYLY----GILEERKNEMT---QVITRTQEEKLEH  243

Query  94   LQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSLAPYAQDTQ-E  151
            ++A ++ ++D L     +NV +L      + DE ++ +  Q  + L + ++  ++  Q E
Sbjct  244  VRALIKKYSDHL-----ENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQME  298

Query  152  KLNHQLEGLT-FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE  210
            K+ H  E +  F +  N EE          ++ + +    ED         EG ++   E
Sbjct  299  KIEHGYENMNHFTVNLNREE----------KIIREIDFYREDEDEEEEEGGEGEKEGEGE  348

Query  211  LGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA  252
            +GG   +  E    + E  GE+ N     ++ Q+  +  P A
Sbjct  349  VGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGA  390


>gi|82581558|sp|Q8TDY2|RBCC1_HUMAN  RB1-inducible coiled-coil protein 1
Length=1594

 Score = 37.4 bits (85),  Expect = 0.009
 Identities = 32/169 (18%), Positives = 76/169 (44%), Gaps = 13/169 (7%)

Query  87    LRENADSLQASLRPHADELKAKIDQNVEELKG----RLTPYADEFKVKIDQTVEELRRSL  142
             L   A  ++ +L+    EL++K+D  +  L+     ++T   ++++  I    ++ ++ +
Sbjct  1161  LHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLV  1220

Query  143   APYAQDTQE---KLNHQ----LEGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDV  193
             +   QD ++   KLN +    ++    + K   E ++  +    + L  ++A  P  +  
Sbjct  1221  SSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDST  1280

Query  194   RGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME  242
             RG+       LQ+ L E      +Q+EE  +R     +N   +L+ + +
Sbjct  1281  RGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQ  1329


>gi|62511894|sp|P07196|NFL_HUMAN  Neurofilament triplet L protein (68 kDa neurofilament protein) 
(Neurofilament light polypeptide) (NF-L)
Length=543

 Score = 37.0 bits (84),  Expect = 0.012
 Identities = 54/232 (23%), Positives = 100/232 (43%), Gaps = 33/232 (14%)

Query  49   LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL---  105
            L   + T +  AL  ++ G  E LR     Y +  E + RE+A+      R  ADE    
Sbjct  148  LAAEDATNEKQALQGEREGLEETLRNLQARYEE--EVLSREDAEGRLMEARKGADEAALA  205

Query  106  KAKIDQNVEELKGRLTPYADEFKVKI-DQTVEELRRSLAPYAQDTQEK--LNHQLEGLTF  162
            +A++++ ++ L   ++     F  K+ ++ + EL+  +  YAQ + E       L     
Sbjct  206  RAELEKRIDSLMDEIS-----FLKKVHEEEIAELQAQIQ-YAQISVEMDVTKPDLSAALK  259

Query  163  QMKKNAEELKARISASAEE-LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE  221
             ++   E+L A+   +AEE  + R   L E    N    T+ ++ +  E        V E
Sbjct  260  DIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKN----TDAVRAAKDE--------VSE  307

Query  222  FRRRVEPYG------ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR  267
             RR ++            N+AL +Q+++L  K       ++  ++ LE +LR
Sbjct  308  SRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELR  359


>gi|41688595|sp|Q9UJC3|HOOK1_HUMAN  Hook homolog 1 (h-hook1) (hHK1)
Length=728

 Score = 37.0 bits (84),  Expect = 0.012
 Identities = 44/185 (23%), Positives = 79/185 (42%), Gaps = 19/185 (10%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHA  102
            +E  E+ +  EL +QL    + K+ E E  +R      + +++ + +   SLQ       
Sbjct  481  QEGSENERIEELQEQLEQKHR-KMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKSE  539

Query  103  DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF  162
             E  +K+ Q +E    +LT   +E + K     +EL   L P      +K+N     L  
Sbjct  540  GESSSKLKQKLEAHMEKLTEVHEELQKK-----QELIEDLQPDINQNVQKINE----LEA  590

Query  163  QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF  222
             ++K  E++KA        + +R     E  R  ++     L  + AE+   L +Q+ E 
Sbjct  591  ALQKKDEDMKA--------MEERYKMYLEKARNVIKTLDPKLNPASAEI-MLLRKQLAEK  641

Query  223  RRRVE  227
             RR+E
Sbjct  642  ERRIE  646


>gi|29336622|sp|Q14683|SMC1A_HUMAN  Structural maintenance of chromosome 1-like 1 protein (SMC1alpha 
protein) (DXS423E protein) (Sb1.8)
Length=1233

 Score = 37.0 bits (84),  Expect = 0.012
 Identities = 47/208 (22%), Positives = 89/208 (42%), Gaps = 43/208 (20%)

Query  42   AKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYA---QRMERVLRENADSLQASL  98
            AK+++++ QK          ++ + G+ ++L +++       Q  E  + E + S    L
Sbjct  315  AKKSLQNAQKH---------YKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDL  365

Query  99   RPHADELKAKIDQNVEELKGRLTPYADEF-KVKIDQTVEELRRSLAPYAQ-DTQEKLNHQ  156
                +++K K  +  EE   R    A E  K   DQ  ++ R  L    + +T+ K+  +
Sbjct  366  TLEENQVK-KYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQK  424

Query  157  LEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLD  216
            L  +  + +K  E+L+  I+ S + L ++                        +L G L 
Sbjct  425  LREIE-ENQKRIEKLEEYITTSKQSLEEQ-----------------------KKLEGELT  460

Query  217  QQVEEFRRRVEPYGENFNKALVQQMEQL  244
            ++VE  +RR+    +  NK L Q MEQL
Sbjct  461  EEVEMAKRRI----DEINKELNQVMEQL  484


>gi|2501084|sp|Q16623|STX1A_HUMAN  Syntaxin-1A (Neuron-specific antigen HPC-1)
Length=288

 Score = 37.0 bits (84),  Expect = 0.012
 Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 26/149 (17%)

Query  85   RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SL  142
            R  +++ D    ++    D    +  + VEE++G        F  KI + VEE++R  S 
Sbjct  9    RTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRG--------FIDKIAENVEEVKRKHSA  60

Query  143  APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE  202
               + +  EK   +LE L   +KK A ++++++ +  + + Q                 E
Sbjct  61   ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQE----------------E  104

Query  203  GLQKSLAELGGHLDQQVEEFRRRVEPYGE  231
            GL +S A+L     Q     R+ VE   E
Sbjct  105  GLNRSSADLRIRKTQHSTLSRKFVEVMSE  133


>gi|78099183|sp|Q9H2K8|TAOK3_HUMAN  Serine/threonine-protein kinase TAO3 (Thousand and one amino 
acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK-inhibitory 
kinase) (Dendritic-cell derived protein kinase) (Cutaneous 
T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen 
HD-CL-09) (Kinase from chicken homolog A) (hKFC-A)
Length=898

 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 36/168 (21%), Positives = 75/168 (44%), Gaps = 10/168 (5%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF  127
            +  +LR Q++ Y +RM R  ++   +L+  L+   DE + K+ + VE      +   ++ 
Sbjct  453  QENELREQMSGY-KRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKL  511

Query  128  KVKIDQTVE-ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL  186
              K    +E E + + A   +  Q+ L  Q + LT  ++   ++ K       EE+ +  
Sbjct  512  AKKQVAIIEKEAKVAAADEKKFQQQILAQQKKDLTTFLESQKKQYKICKEKIKEEMNEDH  571

Query  187  APLAEDVRGNLRGNTEGLQKSLAELGGHL--------DQQVEEFRRRV  226
            +   ++ +  +  + E LQ + AE   HL        D+    F+R++
Sbjct  572  STPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKI  619


 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 38/216 (17%), Positives = 88/216 (40%), Gaps = 13/216 (6%)

Query  35   FSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQR---MERVLRENA  91
            + QL    K  ++ ++    T+  N L  +K  E E  R+ +    Q+   ++ +  +  
Sbjct  661  YRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQIK  720

Query  92   DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE  151
               Q + +    + KA  +  +E     +TP  +E K  +    +E  R LA  A+  ++
Sbjct  721  KQFQDTCKVQTKQYKALKNHQLE-----VTP-KNEHKTILKTLKDEQTRKLAILAEQYEQ  774

Query  152  KLNHQLEGLTFQMKKNAEE----LKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS  207
             +N  +     ++ +  E     L+ ++    E L    + +            + L++ 
Sbjct  775  SINEMMASQALRLDEAQEAECQALRLQLQQEMELLNAYQSKIKMQTEAQHERELQKLEQR  834

Query  208  LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
            ++    HL+Q++EE    ++       K L+++ E+
Sbjct  835  VSLRRAHLEQKIEEELAALQKERSERIKNLLERQER  870


>gi|74762299|sp|Q6DT37|MRCKG_HUMAN  Serine/threonine-protein kinase MRCK gamma (CDC42-binding protein 
kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding 
kinase gamma) (Myotonic dystrophy protein kinase-like 
alpha) (MRCK gamma) (DMPK-like gamma)
Length=1551

 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 65/270 (24%), Positives = 110/270 (40%), Gaps = 57/270 (21%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRP-----HADELKAKIDQNVEEL-KGRLT  121
            E EQLR+++     R+  +LR+ A   Q    P        +L+ ++D+   EL +GR  
Sbjct  445  ELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAG  504

Query  122  PYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK---NAEELKARISAS  178
              A E ++   Q  +E        AQ+ +     Q   L+ Q+++      EL+A++S+ 
Sbjct  505  LQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSL  564

Query  179  AEEL-------RQRLAPLAEDVRGNLRGNTEG------------LQKSLAELGGHLDQ--  217
            + ++        QRL   ++    +    T G            L+K +A L   L+Q  
Sbjct  565  SRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAH  624

Query  218  ------------QVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKD  265
                        Q++E  RR+    E     L Q+ E  +Q+L       EG     E+ 
Sbjct  625  SHRRSGKEEALCQLQEENRRLSREQERLEAELAQEQES-KQRL-------EG-----ERR  671

Query  266  LRDKNWGLRLGD-RDESGEEGQSRG-MQAL  293
              + NW  +L D      +E  SRG +QAL
Sbjct  672  ETESNWEAQLADILSWVNDEKVSRGYLQAL  701


>gi|34098465|sp|Q86UP2|KTN1_HUMAN  Kinectin (Kinesin receptor) (CG-1 antigen)
Length=1357

 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 53/232 (22%), Positives = 96/232 (41%), Gaps = 33/232 (14%)

Query  34    YFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADS  93
             Y   L    K+A E +  +  ++++  L + KL EA+++   L    ++ + VL E    
Sbjct  1091  YGEWLHGFEKKAKECMAGTSGSEEVKVL-EHKLKEADEMHTLLQLECEKYKSVLAETEGI  1149

Query  94    LQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL  153
             LQ            K+ ++VE+ + +       +KVK+D++ + +++  + +    QE  
Sbjct  1150  LQ------------KLQRSVEQEENK-------WKVKVDESHKTIKQMQSSFTSSEQE--  1188

Query  154   NHQLEGLTFQMK--KNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
                LE L  + K  +N    +  +    E+     +    +VR  L+     LQK L + 
Sbjct  1189  ---LERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVR-ELKDLLTELQKKLDDS  1244

Query  212   GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLE  263
                  +Q EE         E   K   +Q E  RQK+   AGD+      LE
Sbjct  1245  YSEAVRQNEELNLLKAQLNETLTKLRTEQNE--RQKV---AGDLHKAQQSLE  1291


>gi|74746874|sp|Q5VT25|MRCKA_HUMAN  Serine/threonine-protein kinase MRCK alpha (CDC42-binding protein 
kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding 
kinase alpha) (Myotonic dystrophy protein kinase-like 
alpha) (MRCK alpha) (DMPK-like alpha)
Length=1732

 Score = 36.6 bits (83),  Expect = 0.016
 Identities = 46/219 (21%), Positives = 98/219 (44%), Gaps = 20/219 (9%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMER---VLRENADS  93
            +L N +KE  +   + +L  Q      ++L E    +++L  + +  E    ++ +  +S
Sbjct  557  RLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVES  616

Query  94   LQASLRPHADELKAKIDQNVEELKG------RLTPYADEFKVKIDQTVEELRRSLAPYAQ  147
            L+  LR   +  K +++ + E L        +L   ++ +  +++  +E L++    Y+ 
Sbjct  617  LRQELR-RTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSP  675

Query  148  DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRG---NTEGL  204
                 + HQ E     + K   +L+ +     EEL +R    A +++ NL+    ++EG 
Sbjct  676  GVCS-IEHQQE-----ITKLKTDLEKKSIFYEEELSKREGIHANEIK-NLKKELHDSEGQ  728

Query  205  QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
            Q +L +    L  ++E+ RR  +   E F     QQ E+
Sbjct  729  QLALNKEIMILKDKLEKTRRESQSEREEFESEFKQQYER  767


>gi|50401600|sp|Q8N0X7|SPG20_HUMAN  Spartin (Trans-activated by hepatitis C virus core protein 1)
Length=666

 Score = 36.2 bits (82),  Expect = 0.021
 Identities = 41/180 (22%), Positives = 70/180 (38%), Gaps = 24/180 (13%)

Query  52   SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQ  111
            SEL +    LF+D L +   LR Q         R   EN   +    RP +D+LK     
Sbjct  313  SELPEDDRELFEDLLRQMSDLRLQAN-----WNRAEEENEFQIPGRTRPSSDQLKEASGT  367

Query  112  NVEEL------------KGRLTPYADEFKVKIDQTV------EELRRSLAPYAQDTQEKL  153
            +V++L            +G+        +V +   V      EE  + L  +++     +
Sbjct  368  DVKQLDQGNKDVRHKGKRGKRAKDTSSEEVNLSHIVPCEPVPEEKPKELPEWSEKVAHNI  427

Query  154  NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG  213
                  +++ + K AE     I   A +LR+R+ P  + V  +    T+GL  +    GG
Sbjct  428  LSGASWVSWGLVKGAEITGKAIQKGASKLRERIQPEEKPVEVS-PAVTKGLYIAKQATGG  486


>gi|47117086|sp|P61266|STX1C_HUMAN  Syntaxin-1B2
Length=288

 Score = 36.2 bits (82),  Expect = 0.021
 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 26/141 (18%)

Query  89   ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SLAPYA  146
            +++D  +  +    D    +  + VEE++G +         K+ + VE++++  S    A
Sbjct  12   KDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIE--------KLSEDVEQVKKQHSAILAA  63

Query  147  QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK  206
             +  EK   +LE LT  +KK A ++++++ A  + + Q                 EGL +
Sbjct  64   PNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE----------------EGLNR  107

Query  207  SLAELGGHLDQQVEEFRRRVE  227
            S A+L     Q     R+ VE
Sbjct  108  SSADLRIRKTQHSTLSRKFVE  128


>gi|23831094|sp|O00291|HIP1_HUMAN  Huntingtin-interacting protein 1 (HIP-I)
Length=1030

 Score = 36.2 bits (82),  Expect = 0.021
 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%)

Query  132  DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
            D  +E L R ++       E +  + + +  Q+K +  EL+A + A  + LRQ+ A   E
Sbjct  367  DHLIERLYREISGLKAQL-ENMKTESQRVVLQLKGHVSELEADL-AEQQHLRQQAADDCE  424

Query  192  DVRGNL------RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR  245
             +R  L      R +TE  Q+SL+E+        + + +  E Y E     LVQ    L 
Sbjct  425  FLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSE-----LVQNHADLL  479

Query  246  QK  247
            +K
Sbjct  480  RK  481


>gi|74762068|sp|Q9Y5S2|MRCKB_HUMAN  Serine/threonine-protein kinase MRCK beta (CDC42-binding protein 
kinase beta) (Myotonic dystrophy kinase-related CDC42-binding 
kinase beta) (Myotonic dystrophy protein kinase-like beta) 
(MRCK beta) (DMPK-like beta)
Length=1711

 Score = 35.8 bits (81),  Expect = 0.028
 Identities = 54/261 (20%), Positives = 117/261 (44%), Gaps = 39/261 (14%)

Query  50   QKSELTQQLNALFQDKL---GEAEQLRRQLTPYAQRMERVLRENADSLQ---ASLRPHAD  103
            ++ + TQ+L  L +       E E+L +QL   ++R++   +E  D+ Q    +L+  ++
Sbjct  520  EREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSE  579

Query  104  --ELKAKIDQNVEELKGRLTPYADEFKV---KIDQTVEELRRSLAPYAQDTQEKLNHQLE  158
              E  A++    +++  +L    +E +V   K+D   +E+RR     A+  +++L  QL+
Sbjct  580  LNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRR-----AEKLRKELEAQLD  634

Query  159  GLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
                +  K   +L+       +++   L  L     G   G T   Q+ ++++   L+++
Sbjct  635  DAVAEASKE-RKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKK  693

Query  219  V----EEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLR  274
            V    EE  RR   +        V +++ +++++     D E H   L+K++      L 
Sbjct  694  VLFYEEELVRREASH--------VLEVKNVKKEV----HDSESHQLALQKEI------LM  735

Query  275  LGDRDESGEEGQSRGMQALQG  295
            L D+ E  +  +   M+   G
Sbjct  736  LKDKLEKSKRERHNEMEEAVG  756


>gi|2506805|sp|P24043|LAMA2_HUMAN  Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy 
chain)
Length=3110

 Score = 35.8 bits (81),  Expect = 0.028
 Identities = 37/120 (30%), Positives = 58/120 (48%), Gaps = 14/120 (11%)

Query  151   EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE  210
             E+ N + + L   +K+ A + +A ++  A +L + L    E    NL    EGLQK +  
Sbjct  1669  ERTNTRAKSLGEFIKELARDAEA-VNEKAIKLNETLGTRDEAFERNL----EGLQKEI--  1721

Query  211   LGGHLDQQVEEFRRR-VEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
                  DQ ++E RR+ +E   E     LV   E L +K+    G+  G    +EKDLR+K
Sbjct  1722  -----DQMIKELRRKNLETQKEIAEDELV-AAEALLKKVKKLFGESRGENEEMEKDLREK  1775


 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 49/236 (20%), Positives = 89/236 (37%), Gaps = 16/236 (6%)

Query  41    NAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRP  100
             N K      +K E  +      ++ L E   +  +    A  +  ++ +  + +Q  L P
Sbjct  1807  NQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSII-DYVEDIQTKLPP  1865

Query  101   HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG-  159
              ++EL  KID   +E+K R      E   + +    +L  S A       E  N      
Sbjct  1866  MSEELNDKIDDLSQEIKDRKLA---EKVSQAESHAAQLNDSSAVLDGILDEAKNISFNAT  1922

Query  160   LTFQMKKNAEEL---KARISASAEELRQRLAPLAEDVRGNLRGNTEG-LQKSLAELGGHL  215
               F+   N ++      +++  A++L      LA   RG L+ + +G LQKS   L    
Sbjct  1923  AAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRIL----  1978

Query  216   DQQVEEFRRRVEPYGENFN--KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
               + ++    V+   ++ N  K  ++  +     L     D  G LS +  D   K
Sbjct  1979  -NEAKKLANDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAK  2033


 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 35/166 (21%), Positives = 72/166 (43%), Gaps = 27/166 (16%)

Query  130   KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
             +IDQ ++ELRR      ++  E      E L  ++KK   E +       ++LR++LA  
Sbjct  1720  EIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADY  1779

Query  190   ---AEDVRGNLRGNTEGL----------QKSLAELGGHLDQQVEEFRRRVEPYGENFN--  234
                 +D    LR  T+ +          QK++  L     + VE  +R++E   +  N  
Sbjct  1780  KNKVDDAWDLLREATDKIREANRLFAVNQKNMTAL-EKKKEAVESGKRQIENTLKEGNDI  1838

Query  235   -----------KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
                         +++  +E ++ KL P + ++   +  L ++++D+
Sbjct  1839  LDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDR  1884


>gi|33301318|sp|Q92614|MY18A_HUMAN  Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule 
associated with JAK3 N-terminus) (MAJN)
Length=2054

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 54/263 (20%), Positives = 112/263 (42%), Gaps = 43/263 (16%)

Query  50    QKSELTQQ---LNALFQDKLGEAEQLRRQLTPYAQRME---RVLRENADSLQASLRPHAD  103
             Q+ EL +Q   +  L Q KL    ++ R    +++ ME     + E   S Q  L+    
Sbjct  1554  QEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEV  1613

Query  104   EL------KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL---APYAQDTQEKLN  154
             +L      K K+ +   EL+G+L   +D+   +  ++ + LR+ L        D Q  L+
Sbjct  1614  QLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLD  1673

Query  155   H---------QLEGLTFQMKKN----AEELKAR--ISASAEELRQRLAPLAEDVRGNLRG  199
             H         ++  L  Q++++    A  +KAR  +    E+L  ++  +A+  +  L  
Sbjct  1674  HLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK-AKTALEE  1732

Query  200   NTEGLQKSLAELGGHLDQQVEEFRRRVEPYGE------------NFNKALVQQMEQLRQK  247
                 LQ+   E+   L++  E+    ++ +              N  +A +++  + +Q+
Sbjct  1733  QLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQE  1792

Query  248   LGPHAGDVEGHLSFLEKDLRDKN  270
             L      ++  + FLE+ + DK+
Sbjct  1793  LQEKLQALQSQVEFLEQSMVDKS  1815


>gi|48474780|sp|P78386|KRHB5_HUMAN  Keratin, type II cuticular Hb5 (Hair keratin, type II Hb5)
Length=507

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 46/204 (22%), Positives = 88/204 (43%), Gaps = 29/204 (14%)

Query  48   HLQKSELTQQLNALFQD-----KLGEAE----QLRRQLTPYAQRMERVLRENADSLQASL  98
            +L+KS+L   + AL ++     +L E E    Q     T    +M+     N D + A +
Sbjct  236  YLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEI  295

Query  99   RPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE  158
            +   D++ ++   +  E +       +E K  + +  E LRR+     ++   +LN  ++
Sbjct  296  KAQYDDVASR---SRAEAESWYRSKCEEMKATVIRHGETLRRT-----KEEINELNRMIQ  347

Query  159  GLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
             LT +++ NA+  +A++ A+  E  Q+      D R             LAEL G L + 
Sbjct  348  RLTAEIE-NAKCQRAKLEAAVAEAEQQGEAALSDAR-----------CKLAELEGALQKA  395

Query  219  VEEFRRRVEPYGENFNKALVQQME  242
             ++    ++ Y E  N  L   +E
Sbjct  396  KQDMACLLKEYQEVMNSKLGLDIE  419


>gi|13431563|sp|O75146|HIP1R_HUMAN  Huntingtin-interacting protein 1-related protein (Hip1-related) 
(Hip 12)
Length=1068

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 16/190 (8%)

Query  36   SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
            S+L     EA  ++  ++L  Q+NAL     GE E+ R+Q        E++  E A    
Sbjct  368  SELEKIKLEAQRYI--AQLKSQVNALE----GELEEQRKQKQKALVDNEQLRHELAQLRA  421

Query  96   ASLRPHADE-LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL-----APYAQDT  149
            A L     + L+ + ++     + R     ++    +    E LR++          Q +
Sbjct  422  AQLEGERSQGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQS  481

Query  150  QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL---QK  206
            QE++    E L FQ+++   E + ++   +++L ++L    E   G L    E L   ++
Sbjct  482  QEEVARVKEQLAFQVEQVKRESELKLEEKSDQL-EKLKRELEAKAGELARAQEALSHTEQ  540

Query  207  SLAELGGHLD  216
            S +EL   LD
Sbjct  541  SKSELSSRLD  550


 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 20/135 (14%)

Query  132  DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
            D  +E L+R +        E L  +LE +  + ++   +LK++++A   EL ++     +
Sbjct  353  DLQIESLKREV--------EMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQK  404

Query  192  DVRGNLRGNTEGLQKSLAELGGHLDQQV-EEFRRRVEPYGENFNKALVQQMEQLRQKLGP  250
             +  N +   E  Q   A+L G   Q + EE  R+       +NK        L++K   
Sbjct  405  ALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNK--------LKEK---  453

Query  251  HAGDVEGHLSFLEKD  265
            H+  V  H   L K+
Sbjct  454  HSELVHVHAELLRKN  468


>gi|2501085|sp|Q15531|STX1B_HUMAN  Syntaxin-1B1 (Syntaxin 1B)
Length=288

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 22/99 (22%), Positives = 48/99 (48%), Gaps = 10/99 (10%)

Query  88   RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SLAPY  145
            R N+D  +  +    D    +  +  EE++G +         K+ + VE++++  S    
Sbjct  11   RRNSDDKEEVVHVDRDHFMDEFFEQEEEIRGCIE--------KLSEDVEQVKKQHSAILA  62

Query  146  AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
            A +  E+   +LE LT  +KK A ++++++ A  + + Q
Sbjct  63   APNPDERTKQELEDLTADIKKTANKVRSKLKAIEQSIEQ  101


>gi|51701377|sp|O15083|ERC2_HUMAN  ERC protein 2
Length=957

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 50/214 (23%), Positives = 90/214 (42%), Gaps = 25/214 (11%)

Query  49   LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRME---RVLRENADSLQ------ASLR  99
            L++    + L    + K  E  +L  QL   A  +E   R+  E AD ++      +  R
Sbjct  658  LKRDSKLKSLEIAIEQKKEECSKLEAQLKK-AHNIEDDSRMNPEFADQIKQLDKEASYYR  716

Query  100  PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                + +A++D+ +E LK       +  K   D+ + EL      + +D  +K+ +    
Sbjct  717  DECGKAQAEVDRLLEILKE-----VENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHN  771

Query  160  LTFQMKKNA---EELKARISASAEELR----QRLAPLAEDVRGNL---RGNTEGLQKSLA  209
               + KKNA   EE++ R  + A+  +    + L    E  R  L   +      Q+SLA
Sbjct  772  QQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA  831

Query  210  ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
            E   HL     E R+++E   E   +AL+  + +
Sbjct  832  EKEAHLANLRIERRKQLEEILEMKQEALLAAISE  865


 Score = 33.9 bits (76),  Expect = 0.10
 Identities = 46/215 (21%), Positives = 89/215 (41%), Gaps = 12/215 (5%)

Query  65   KLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYA  124
            ++ EAE     L     + E+      + L    +   +  K K  Q V E+K       
Sbjct  331  RMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASL  390

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ---MKKNAEELKARISASAEE  181
            +     ++  ++ L+ +     +D +E++  Q+E        MK   ++LK  +S    E
Sbjct  391  ERNIRDLEDEIQMLKANGVLNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESE  449

Query  182  L---RQRLAPLAEDVRGNLRGNTEGLQKSLA---ELGGHLDQQVEEFRRRVEPYGENFNK  235
            L   + +L  L+     + + + E L++SL    +    L  +V+  R R+E   E+F  
Sbjct  450  LLALQTKLETLSNQ-NSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK-ESFLN  507

Query  236  ALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKN  270
               +Q++ L ++ G  AG++      LE   R  N
Sbjct  508  KKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKIN  542


 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 56/238 (23%), Positives = 106/238 (44%), Gaps = 29/238 (12%)

Query  44   EAVEHLQKS--ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV-LRENAD--SLQASL  98
            E +E  +K   +L +++NAL Q +L E E     L  +A  +    L+ ++   SL+ ++
Sbjct  613  EEIESFRKENKDLKEKVNAL-QAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAI  671

Query  99   RPHADE---LKAKIDQ--NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL  153
                +E   L+A++ +  N+E+   R+ P   EF  +I Q  +E     A Y +D   K 
Sbjct  672  EQKKEECSKLEAQLKKAHNIED-DSRMNP---EFADQIKQLDKE-----ASYYRDECGKA  722

Query  154  NHQLEGLTFQMKK--NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
              +++ L   +K+  N +  K +  A  E L  R          NL+ N +  +K  A+L
Sbjct  723  QAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL  782

Query  212  GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK  269
                   +EE RRR +   +N     ++++    +K        +  L+  ++ L +K
Sbjct  783  -------LEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEK  833


>gi|41688592|sp|Q96ED9|HOOK2_HUMAN  Hook homolog 2 (h-hook2) (hHK2)
Length=719

 Score = 35.4 bits (80),  Expect = 0.036
 Identities = 55/233 (23%), Positives = 97/233 (41%), Gaps = 22/233 (9%)

Query  56   QQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL--QASLRPHADELKAKIDQNV  113
            Q+L    Q++  +AE+   +     ++ E V +E    L  + SLR   +EL+       
Sbjct  370  QELQGQLQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCA-----  424

Query  114  EELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA-----  168
             +L+ R    AD         V+ L   + P A+  +  L  QLE      ++ A     
Sbjct  425  -QLQPRGLTQADPSLDPTSTPVDNLAAEILP-AELRETLLRLQLENKRLCRQEAADRERQ  482

Query  169  EELKARISASAEELRQRLAP---LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE-EFRR  224
            EEL+  +   A   R  L     L +     LR   E LQK+L E GG  +  +    +R
Sbjct  483  EELQRHLE-DANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDAISILLKR  541

Query  225  RVEPYGENFNKA---LVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLR  274
            ++E + +  ++A   L ++ E + +   P        +  L+ +L+ K+  LR
Sbjct  542  KLEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKKDADLR  594


>gi|17368936|sp|Q9H169|STMN4_HUMAN  Stathmin-4 (Stathmin-like protein B3) (RB3)
Length=189

 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 0/89 (0%)

Query  182  LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQM  241
            L +R  P  E+++  L    E  +   AEL  HL ++ E  R  ++   E  N  +    
Sbjct  83   LPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAK  142

Query  242  EQLRQKLGPHAGDVEGHLSFLEKDLRDKN  270
            E+L QK+  +  + E HL+ + + L++K+
Sbjct  143  EKLAQKMESNKENREAHLAAMLERLQEKD  171


 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 1/99 (1%)

Query  169  EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP  228
            EE++ ++ A+ E  + + A L + +        E +QK++ E    +    E+  +++E 
Sbjct  92   EEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMES  151

Query  229  YGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR  267
              EN    L   +E+L++K   HA +V  +    E+  R
Sbjct  152  NKENREAHLAAMLERLQEK-DKHAEEVRKNKELKEEASR  189


>gi|547750|sp|P35900|K1C20_HUMAN  Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) 
(K20) (Protein IT)
Length=424

 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 26/171 (15%)

Query  81   QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
            Q+ E + ++N    +         L+ ++  N EELKG             +  + ELRR
Sbjct  244  QKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKG------------TEVQLTELRR  291

Query  141  SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE---DVRGNL  197
            +    +Q  + +L   L  +   ++   EE KAR S+    L+  L+ L      +R N+
Sbjct  292  T----SQSLEIELQSHL-SMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNM  346

Query  198  -RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
             R N E     L ++   L+Q++  +RR +E  GE+  K    Q+  L ++
Sbjct  347  ERQNNE--YHILLDIKTRLEQEIATYRRLLE--GEDV-KTTEYQLSTLEER  392


>gi|3024609|sp|Q15431|SYCP1_HUMAN  Synaptonemal complex protein 1 (SCP-1 protein)
Length=976

 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 47/220 (21%), Positives = 91/220 (41%), Gaps = 28/220 (12%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTP-------YAQRME--RVLRENADS  93
            ++  E L+ +E  Q+L  L Q +  E   L  QLT        Y++ ++  +   EN   
Sbjct  454  EKIAEELKGTE--QELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKL  511

Query  94   LQASLRPHADELKAKIDQNVEELKGRLTPYADEFK-VKIDQTVEELRRSLAPYAQDTQEK  152
                L  H ++L  +  +  +E         ++ + +  ++  EE         Q+T+ +
Sbjct  512  KNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ  571

Query  153  LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL-  211
            L ++LE +  ++K+  +E+K ++  S E               NLR   E   K + EL 
Sbjct  572  LRNELEYVREELKQKRDEVKCKLDKSEENC------------NNLRKQVENKNKYIEELQ  619

Query  212  --GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG  249
                 L ++     +++  Y    NK L  ++E  +QK G
Sbjct  620  QENKALKKKGTAESKQLNVYEIKVNK-LELELESAKQKFG  658


 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 41/189 (21%), Positives = 75/189 (39%), Gaps = 31/189 (16%)

Query  40   NNAKEAVEHLQK--SELTQQLNALFQDKLGEAEQLR------RQLTPYAQRMERVLRENA  91
            NN ++ VE+  K   EL Q+  AL +    E++QL        +L    +  ++   E  
Sbjct  602  NNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEIT  661

Query  92   DSLQASLRPH-----------------ADE---LKAKIDQNVEELKGRLTPYADEFKVKI  131
            D+ Q  +                    ADE   L+ +ID+  +     +    ++ K + 
Sbjct  662  DTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQY  721

Query  132  DQTVEELRRSLAPYAQDTQEK--LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
            D+ +EE    L  Y    QE+  L   LE     +K     +K ++    EE +++L   
Sbjct  722  DKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREE-KEKLKRE  780

Query  190  AEDVRGNLR  198
            A++    L+
Sbjct  781  AKENTATLK  789


>gi|74736716|sp|Q6NSJ2|PHLB3_HUMAN  Hypothetical pleckstrin homology-like domain family B member 
3
Length=279

 Score = 35.0 bits (79),  Expect = 0.047
 Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 42/193 (21%)

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY---AQDTQEKLNHQLEGLTFQ  163
            A ++Q V+EL+ +      E +++++  V  LR  LA     A+  +E+L   LE     
Sbjct  113  ALMEQRVKELQRQ----RKELRIEMEVEVALLRGELAGERVAARREEEQLRELLE-----  163

Query  164  MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
             ++ A E + R     E+ R     L+++     R   EGL++ L +  G LD Q E+ R
Sbjct  164  -QQAASEQRGRQQREQEQRR-----LSQE-----RDRLEGLRQRLRKAQGQLDSQPEDQR  212

Query  224  RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF--LEKDLRDKNWGLRLGDRDES  281
             R           L+Q ++++R++L       E  L F  LE++ R +       DRD  
Sbjct  213  ER-----------LLQGVQEMREQLDVAQRAYE-DLEFRQLERESRQEE-----EDRDSP  255

Query  282  GEEGQSRGMQALQ  294
            G +     +Q LQ
Sbjct  256  GPQVPDPKVQELQ  268


>gi|51827892|sp|Q8IUD2|RB6I2_HUMAN  RAB6-interacting protein 2 (ERC protein 1)
Length=1116

 Score = 34.7 bits (78),  Expect = 0.061
 Identities = 45/211 (21%), Positives = 86/211 (40%), Gaps = 30/211 (14%)

Query  39   SNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRM------ERVLRENAD  92
            S+ A+  V+ L   E+ +++     DK  +  +L RQ+    +++      E+V ++ + 
Sbjct  751  SSKAQAEVDRLL--EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA  808

Query  93   SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK  152
             +    R   D L     Q  + L+            K D  +EEL  +L    Q T E+
Sbjct  809  QMLEEARRREDNLNDSSQQLQDSLR------------KKDDRIEELEEALRESVQITAER  856

Query  153  LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELG  212
                +       + NAE+    +  + E+++Q L         +++      Q+SLAE  
Sbjct  857  --EMVLAQEESARTNAEKQVEELLMAMEKVKQELE--------SMKAKLSSTQQSLAEKE  906

Query  213  GHLDQQVEEFRRRVEPYGENFNKALVQQMEQ  243
             HL     E R+ +E   E   +AL+  + +
Sbjct  907  THLTNLRAERRKHLEEVLEMKQEALLAAISE  937


>gi|547749|sp|P13645|K1C10_HUMAN  Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) 
(K10)
Length=593

 Score = 34.7 bits (78),  Expect = 0.061
 Identities = 32/164 (19%), Positives = 72/164 (43%), Gaps = 21/164 (12%)

Query  72   LRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKI  131
            L + L     + E++  +N    +A     + EL  +ID N+E+    ++ Y  E     
Sbjct  314  LTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQ----ISSYKSE-----  364

Query  132  DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
               + ELRR++     + Q +L      L   ++ +  E + R      +++ +++ L E
Sbjct  365  ---ITELRRNVQALEIELQSQL-----ALKQSLEASLAETEGRYCVQLSQIQAQISALEE  416

Query  192  DVRGNLRGNTEGLQ---KSLAELGGHLDQQVEEFRRRVEPYGEN  232
             ++  +R  TE      + L ++   L+ +++ +R  +E  G +
Sbjct  417  QLQ-QIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSS  459


>gi|26006960|sp|O75955|FLOT1_HUMAN  Flotillin-1
Length=427

 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 48/212 (22%), Positives = 87/212 (41%), Gaps = 23/212 (10%)

Query  65   KLGEAEQLRRQLTPYAQ-RMERVLRENADSLQASLRPHADELKAK---IDQNVEELKGRL  120
            ++GEAE  R      A+ + E+V  +    ++ +      ELK     I+ N    +  L
Sbjct  177  RIGEAEAKRDAGIREAKAKQEKVSAQYLSEIEMAKAQRDYELKKAAYDIEVNTRRAQADL  236

Query  121  TPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE  180
                   K K  Q +EE R  +    +  Q  +  Q      ++ +  +EL+AR+   AE
Sbjct  237  AYQLQVAKTK--QQIEEQRVQVQVVERAQQVAVQEQ------EIARREKELEARVRKPAE  288

Query  181  ELRQRLAPLAEDVRGNLRGNTEGLQKSLA--------ELGGHLDQQVEEFRRRVEPYGEN  232
              R +L  LAE  +  L    E    S+          +G     + E+  ++ E + + 
Sbjct  289  AERYKLERLAEAEKSQLIMQAEAEAASVRMRGEAEAFAIGARARAEAEQMAKKAEAF-QL  347

Query  233  FNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK  264
            + +A   Q++ L +KL   A ++ G L+   K
Sbjct  348  YQEA--AQLDMLLEKLPQVAEEISGPLTSANK  377


>gi|125081|sp|P19012|K1C15_HUMAN  Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) 
(K15)
Length=456

 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 43/191 (22%), Positives = 80/191 (41%), Gaps = 19/191 (9%)

Query  84   ERVLRENADSLQASLRPHA---DELKAKIDQNVEELKGRLTPYADEFKV-KIDQTVEELR  139
            E++  +N +   AS        +E  A ++  + +   + TP + E    +  +T+EELR
Sbjct  105  EKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPASPECDYSQYFKTIEELR  164

Query  140  RSLAPYAQDTQEKL----NHQLEGLTFQMK-KNAEELKARISASAEELRQRLAPLAEDVR  194
              +     D    +    N +L    F++K +N   L+  + A    LR+ L  L    R
Sbjct  165  DKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTL-AR  223

Query  195  GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY---------GENFNKALVQQMEQLR  245
             +L    EGL + LA L  + +++++EF  ++            G +  + L +  EQ  
Sbjct  224  TDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYE  283

Query  246  QKLGPHAGDVE  256
                 +  DVE
Sbjct  284  AMAEKNRRDVE  294


 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 41/186 (22%), Positives = 75/186 (40%), Gaps = 35/186 (18%)

Query  38   LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            L  N +E ++    S+L  Q+N       G    L R L    ++ E +  +N   ++A 
Sbjct  240  LKKNHEEEMKEFS-SQLAGQVNVEMDAAPGV--DLTRVLAEMREQYEAMAEKNRRDVEAW  296

Query  98   LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
                 +EL  ++  N E ++   T   D            LRR++    Q+ + +L  QL
Sbjct  297  FFSKTEELNKEVASNTEMIQTSKTEITD------------LRRTM----QELEIELQSQL  340

Query  158  EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ  217
                         +KA +  S  E   R A   + ++G +     GL+  L+EL   ++ 
Sbjct  341  ------------SMKAGLENSLAETECRYATQLQQIQGLI----GGLEAQLSELRCEMEA  384

Query  218  QVEEFR  223
            Q +E++
Sbjct  385  QNQEYK  390


>gi|26392576|sp|Q9NUD7|CT096_HUMAN  Protein C20orf96
Length=363

 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 52/223 (23%), Positives = 95/223 (42%), Gaps = 28/223 (12%)

Query  33   DYFSQLSNNAKEAVEHLQKSELTQQLNALFQ---------DKLGEAEQLR-RQLTPYAQR  82
            ++ S+L+    E ++ ++ S  T  + AL Q         D L  + + R +QL    Q 
Sbjct  120  NFLSKLNRELIETIQEMENST-TLHVRALLQQQDTLATIIDILEYSNKKRLQQLKSELQE  178

Query  83   MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
             E    E      + L   A++L AKI++  EE+    T    E+ +K  Q +  L R L
Sbjct  179  WE----EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ-ISTLMRQL  233

Query  143  APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE  202
                Q  ++    +L+ L    +K  E L  +I    +++      L+  V    R   E
Sbjct  234  ----QQVKDSQQDELDDLGEMRRKVLESLSDKIQKKKKKI------LSSVVAETQRPYEE  283

Query  203  GLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR  245
             L + + E    L + ++ FR  ++ + EN    L  ++E+L+
Sbjct  284  ALLQKMWESQDFL-KCMQRFREIIDQFEENM-PVLRAEVEELQ  324


>gi|32699565|sp|Q8IUG5|MY18B_HUMAN  Myosin-18B (Myosin XVIIIb)
Length=2567

 Score = 34.3 bits (77),  Expect = 0.080
 Identities = 53/255 (20%), Positives = 111/255 (43%), Gaps = 29/255 (11%)

Query  43    KEAVEHLQKSELTQQ-LNALFQDKLGEAEQLRRQLTPYAQRMERV-------LRENADSL  94
             KE +  L+ S L QQ + +  ++ + + EQLR++     +RM+++         E  + +
Sbjct  1687  KERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDV  1746

Query  95    QASLRPHADELKAKIDQNVEE----------LKGRLTPYADEFKVKIDQTVEELRRSLA-  143
             + S +    +L+ +++Q  EE          L+G +    D+   +     + LRR L  
Sbjct  1747  RQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRR  1806

Query  144   --PYAQDTQEKLNHQLEGLTFQMKKNAEELKARI---SASAEELRQRLAPLAEDVRGNLR  198
                   D Q  L    +G T   K+  E++ +++    A  EE  +    L  D+  ++ 
Sbjct  1807  THALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLE-SMH  1865

Query  199   GNTEGL--QKSLA-ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDV  255
                E +   KSL  E    L  +  +  +R++   ++ N+ L+Q+ + L  +     G +
Sbjct  1866  SELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNE-LMQKHKDLIAQSAADIGQI  1924

Query  256   EGHLSFLEKDLRDKN  270
             +     LE+  ++K+
Sbjct  1925  QELQLQLEEAKKEKH  1939


>gi|13124319|sp|O60282|KIF5C_HUMAN  Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 
2)
Length=957

 Score = 33.9 bits (76),  Expect = 0.10
 Identities = 49/245 (20%), Positives = 102/245 (41%), Gaps = 18/245 (7%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNAL-FQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
            QL  +     E L K    ++++ + FQDK  E     +      + +E+ +  + ++ Q
Sbjct  656  QLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ  715

Query  96   ASLRPHADEL--KAKIDQNVEELKGRLTPYADEF-----KVKIDQTVEELRRSLAPYAQD  148
              L    DE+  K KI   + +L  +L    ++      K+KI+    E++        D
Sbjct  716  KQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLND  775

Query  149  TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL  208
             +E+    L+GL   + +  + L        ++L  R+    E +  +  G +   ++ +
Sbjct  776  KREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVE-LDNDDGGGSAAQKQKI  834

Query  209  AELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFL----EK  264
            + L  +L+Q  +  ++ V       N  L  ++ +L ++L   A  V+   S L    E 
Sbjct  835  SFLENNLEQLTKVHKQLVRD-----NADLRCELPKLEKRLRATAERVKALESALKEAKEN  889

Query  265  DLRDK  269
             +RD+
Sbjct  890  AMRDR  894


>gi|46397807|sp|O76014|K1H7_HUMAN  Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7)
Length=449

 Score = 33.9 bits (76),  Expect = 0.10
 Identities = 54/226 (23%), Positives = 101/226 (44%), Gaps = 42/226 (18%)

Query  40   NNAKEAVEHLQ-KSELTQQLNALFQ-DKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            +NAK A +  + K E  + L+ L + DK G  ++L    T        + + + ++ Q S
Sbjct  180  DNAKLAADDFRIKLESERSLHQLVEADKCG-TQKLLDDAT--------LAKADLEAQQES  230

Query  98   LRPHADELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSL----APYA------  146
            L+     LK+  +Q V+ L+ +L    ++F++++D +   +L R L    A Y       
Sbjct  231  LKEEQLSLKSNHEQEVKILRSQL---GEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETN  287

Query  147  -QDTQEKLNHQLEGLTFQMKKNAEELKA--------RISASAEELRQRLAPLAEDVRGNL  197
             QD ++    Q EG++ Q    +EEL+         R + +A E+ ++     +D   N 
Sbjct  288  HQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNS  347

Query  198  ------RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL  237
                  R  TE  Q  +  L  +L++Q+ E R  +E   + +   L
Sbjct  348  LCEAEDRYGTELAQ--MQSLISNLEEQLSEIRADLERQNQEYQVLL  391


>gi|23822112|sp|Q9P2E9|RRBP1_HUMAN  Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa 
ribosome receptor homolog) (ES/130-related protein)
Length=1410

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 58/254 (22%), Positives = 98/254 (38%), Gaps = 34/254 (13%)

Query  24    ADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDK-------LGEAEQLRRQ-  75
             ADQ  T + +  SQ+S   KEA+E  +  E  +  N   ++K       L  AEQ  ++ 
Sbjct  982   ADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEK  1041

Query  76    ---LTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEE------------LKGRL  120
                LT   +  E+ L         +L     EL     QN  E            LK   
Sbjct  1042  LLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPP  1101

Query  121   TPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE----LKARIS  176
              P      +       E  +S      D    +  + EG+   ++K+ EE     +A++ 
Sbjct  1102  APAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVG  1161

Query  177   ASAEELRQRLAPL--AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN  234
             A+ EEL++    +   E++   L+G  E     + E   HL+ ++E+         +N+ 
Sbjct  1162  AAEEELQKSRVTVKHLEEIVEKLKGELES-SDQVREHTSHLEAELEKHMAAASAECQNYA  1220

Query  235   KALVQQMEQLRQKL  248
             K    ++  LRQ L
Sbjct  1221  K----EVAGLRQLL  1230


>gi|48474671|sp|Q9NSB2|KRHB4_HUMAN  Keratin, type II cuticular Hb4 (Hair keratin, type II Hb4)
Length=600

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 39/172 (22%), Positives = 69/172 (40%), Gaps = 18/172 (10%)

Query  52   SELTQQLNALFQDKL---GEAEQLRRQLTPYAQRMER--VLRENADSLQASLRPHAD---  103
            + L +QL  L  D+     E   L+  L  + ++ E   V R NA++   +L+   D   
Sbjct  219  TNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAF  278

Query  104  ----ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                +L+A +D   +E+    T Y +E ++        +  +      D    LN  L+G
Sbjct  279  MNKSDLEANVDTLTQEIDFLKTLYMEEIQL----LQSHISETSVIVKMDNSRDLN--LDG  332

Query  160  LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
            +  ++K   EE+  R  A AE   Q      +   G    N   ++  + EL
Sbjct  333  IIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINEL  384


>gi|399227|sp|Q02224|CENPE_HUMAN  Centromeric protein E (CENP-E protein)
Length=2663

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 37/214 (17%), Positives = 92/214 (42%), Gaps = 35/214 (16%)

Query  37    QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
             QL  + +E +  +Q+S+  Q+ +   ++K  E  ++  ++  +  +   +LR   + L  
Sbjct  1367  QLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGL  1426

Query  97    SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ  156
             S R         + ++ +E+K                       S+A    D Q +L   
Sbjct  1427  SKR---------LQESHDEMK-----------------------SVAKEKDDLQ-RLQEV  1453

Query  157   LEGLTFQMKKNAEELKARISASAEELRQRLAPL--AEDVRGNLRGNTEGLQKSLAELGGH  214
             L+  + Q+K+N +E+ A+   + EEL+     L   E+    LR N    +  ++ +   
Sbjct  1454  LQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQ  1513

Query  215   LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
             L+   ++ + +++   E   +  ++Q+ ++++ +
Sbjct  1514  LEAINDKLQNKIQEIYEKEEQLNIKQISEVQENV  1547


 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 35/169 (20%), Positives = 74/169 (43%), Gaps = 21/169 (12%)

Query  54    LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNV  113
             +T +   L  +K+ E E    +    A   E  + +    L+ +     +++ AK+   V
Sbjct  2333  VTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVT-----NDIIAKLQAKV  2387

Query  114   EELKGRLTPYADEFKVKIDQTVEELRRSLA----PYAQDTQEKLNHQLEGLTFQMKKNAE  169
              E        +++   K  +T++ L+  +A    PY ++ ++ L  +L  +  +  KNA+
Sbjct  2388  HE--------SNKCLEKTKETIQVLQDKVALGAKPYKEEIED-LKMKLVKIDLEKMKNAK  2438

Query  170   ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
             E +  ISA+   +  +   +   +R NLR + +    S+  +  H D Q
Sbjct  2439  EFEKEISATKATVEYQ-KEVIRLLRENLRRSQQAQDTSV--ISEHTDPQ  2484


>gi|6685537|sp|Q14152|IF3A_HUMAN  Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 
theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a)
Length=1382

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 22/156 (14%)

Query  37   QLSNNAKEAVEHL----QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
            Q     KE +E L    +K EL Q+   L + +  E E+LR++     +  ER+L+E+  
Sbjct  573  QTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE--REKERILQEHEQ  630

Query  93   SLQASLRPHADEL-------KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY  145
              + ++R   +++       KA  D ++E+L+  L P  D    K  + +E+ ++ L   
Sbjct  631  IKKKTVRERLEQIKKTELGAKAFKDIDIEDLE-ELDP--DFIMAKQVEQLEKEKKELQER  687

Query  146  AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEE  181
             ++ ++K+++      F+  K  EE+    SA  E+
Sbjct  688  LKNQEKKIDY------FERAKRLEEIPLIKSAYEEQ  717


>gi|543742|sp|P35609|ACTN2_HUMAN  Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin 
cross linking protein)
Length=894

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 45/219 (20%), Positives = 94/219 (42%), Gaps = 29/219 (13%)

Query  32   WDYFSQLSNNAKEAVEHLQK-SELTQQLNALFQDKL--------GEAEQLRRQLTPYAQR  82
            WD    L+   +EA+E ++K  E   QL+  F  +         G  E L+     ++  
Sbjct  490  WDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIE  549

Query  83   MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
              + L    +  +A+L P AD  +    Q++  ++  +      + ++I         S 
Sbjct  550  EIQSLITAHEQFKATL-PEADGER----QSIMAIQNEVEKVIQSYNIRIS--------SS  596

Query  143  APYAQDTQEKLN---HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRG  199
             PY+  T ++L     +++ L     ++ +E  AR  A+ E LR++ A  A  +   ++ 
Sbjct  597  NPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHAN-ERLRRQFAAQANAIGPWIQN  655

Query  200  NTEGLQKSLAELGGHLD---QQVEEFRRRVEPYGENFNK  235
              E + +S  ++ G L+    Q++++   +  Y  N +K
Sbjct  656  KMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDK  694


>gi|417216|sp|P33176|KINH_HUMAN  Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC)
Length=963

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 58/265 (21%), Positives = 109/265 (41%), Gaps = 32/265 (12%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYA----QRMERVLRENAD  92
            Q     +E+V+ L  SE   QL A  Q+K+ E E+        A    Q +E+ ++ + +
Sbjct  655  QKKRQLEESVDAL--SEELVQLRA--QEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRE  710

Query  93   SLQASLRPHADEL--KAKIDQNVEELKGRLTPYADEFKV---KIDQTVEELRRSLAPYA-  146
            + Q  +    DE+  KAK+  ++++   ++    +  +V   K+  T +E  R L     
Sbjct  711  THQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTV  770

Query  147  -QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE----DVRGN-----  196
             QD +E+    L+GL   + K  + L        ++L  R+   AE    D  G+     
Sbjct  771  MQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQ  830

Query  197  ----LRGNTEGL---QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG  249
                L  N E L    K L      L  ++ +  +R+    E   KAL   +++ ++   
Sbjct  831  KISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERV-KALESALKEAKENAS  889

Query  250  PHAGDVEGHLSFLEKDLRDKNWGLR  274
                  +  +  +++ +R KN   R
Sbjct  890  RDRKRYQQEVDRIKEAVRSKNMARR  914


>gi|29839561|sp|Q8NF91|SYNE1_HUMAN  Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic 
nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope 
protein 1) (Myne-1) (Enaptin)
Length=8797

 Score = 33.5 bits (75),  Expect = 0.14
 Identities = 43/208 (20%), Positives = 87/208 (41%), Gaps = 18/208 (8%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA---------DSLQASLRP  100
             Q+  L +   + +Q+     +QL RQL    +   +V  E            SL  SL+ 
Sbjct  4768  QRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQD  4827

Query  101   HADELKAKIDQNVEELKGRLTPYA-DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                 LK ++  ++E+L   L P A ++ + +I     EL+   +   +   E  +  ++ 
Sbjct  4828  SGIVLK-RVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQS  4886

Query  160   LTFQMKKN-----AEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
             + FQ + +        +KA +S     L   L  + E++R  ++ + E +Q SL  +   
Sbjct  4887  IDFQTEMSRSLDWLRRVKAELSGPV-YLDLNLQDIQEEIR-KIQIHQEEVQSSLRIMNAL  4944

Query  215   LDQQVEEFRRRVEPYGENFNKALVQQME  242
               ++ E+F +  E    +   +L +  E
Sbjct  4945  SHKEKEKFTKAKELISADLEHSLAELSE  4972


 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 42/205 (20%), Positives = 85/205 (41%), Gaps = 23/205 (11%)

Query  54    LTQQLNALFQDKLGEAEQLRRQLTPYA--QRMERVLRENADSLQASLRPHADELKAKIDQ  111
             L ++++ +     G+ + L  +L      QR E+ L+          R  ADEL + +  
Sbjct  6050  LAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQR--------YRCEADELDSWLLS  6101

Query  112   NVEELKGRLTPYADEFKVKID-----QTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
                 L   L+P  +   ++         + E+ + +   ++ +    N  LEG     K 
Sbjct  6102  TKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKA-HTKD  6160

Query  167   NAEELKA---RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
              AE+L     R+  S  EL++ L     D + N++G  +  ++S  +L       V+E+ 
Sbjct  6161  EAEQLAGKLRRLKGSLLELQRAL----HDKQLNMQGTAQEKEESDVDLTATQSPGVQEWL  6216

Query  224   RRVEPYGENFNKALVQQMEQLRQKL  248
              +         ++ +QQ ++L Q+L
Sbjct  6217  AQARTTWTQQRQSSLQQQKELEQEL  6241


>gi|2498281|sp|Q16204|CCDC6_HUMAN  Coiled-coil domain-containing protein 6 (H4 protein) (Papillary 
thyroid carcinoma-encoded protein)
Length=585

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 39/175 (22%), Positives = 83/175 (47%), Gaps = 20/175 (11%)

Query  37   QLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQA  96
            QL +   E  +HL++ +  Q    + + K  E + + +QLT     +E++ RE  D L+ 
Sbjct  151  QLQHEKGELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLT-----LEQLRREKID-LEN  204

Query  97   SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN--  154
            +L    + L  ++ + +++L+       +    K+DQ V     S  P  +D   +++  
Sbjct  205  TLEQEQEALVNRLWKRMDKLEAETRILQE----KLDQPV-----SAPPSPRDISMEIDSP  255

Query  155  -HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL  208
             + +  + F +K   E LK ++ A+  +  +++A   E+ R ++R     LQ+ L
Sbjct  256  ENMMRHIRF-LKNEVERLKKQLRAAQLQHSEKMAQYLEEER-HMREENLRLQRKL  308


>gi|51704330|sp|Q93045|STMN2_HUMAN  Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein)
Length=179

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 19/147 (12%)

Query  110  DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA-PYAQDTQEKLNHQLEGLTFQMKKNA  168
            D  V+++  R +  A E  +K    + E  R+LA P  +D                  + 
Sbjct  39   DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDL-----------------SL  81

Query  169  EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP  228
            EE++ ++ A+ E  + + A + + +        E LQK+L E         E+   ++E 
Sbjct  82   EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ  141

Query  229  YGENFNKALVQQMEQLRQKLGPHAGDV  255
              EN    L   +E+L++K   HA +V
Sbjct  142  IKENREANLAAIIERLQEK-ERHAAEV  167


>gi|47117845|sp|P32856|STX2_HUMAN  Epimorphin (Syntaxin-2)
Length=288

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 2/57 (3%)

Query  130  KIDQTVEELRR--SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
            KI Q VEE+++  S+   A + + K+  +LE L  ++KK A +++A++ A  +   Q
Sbjct  45   KITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ  101


 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 11/84 (13%)

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQE-KLNHQL-------EGLTFQMKKNAEELKARIS  176
            D F       VEE+R S+    Q  +E K NH +       EG   ++K+  E+L   I 
Sbjct  26   DHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEG---KIKEELEDLNKEIK  82

Query  177  ASAEELRQRLAPLAEDVRGNLRGN  200
             +A ++R +L  + +    +  GN
Sbjct  83   KTANKIRAKLKAIEQSFDQDESGN  106


>gi|126366|sp|P07942|LAMB1_HUMAN  Laminin beta-1 chain precursor (Laminin B1 chain)
Length=1786

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 50/232 (21%), Positives = 102/232 (43%), Gaps = 25/232 (10%)

Query  38    LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
             L+ + +E VE L + E+  Q +A     +  AE L  +    A +    ++  AD ++ +
Sbjct  1543  LTEDIRERVESLSQVEVILQHSAA---DIARAEMLLEE-AKRASKSATDVKVTADMVKEA  1598

Query  98    LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
             L   A++ +   ++ +++        ADE      Q  + L  S+      ++E L +  
Sbjct  1599  LE-EAEKAQVAAEKAIKQ--------ADEDI----QGTQNLLTSIESETAASEETLFNAS  1645

Query  158   EGLTFQMKKNAEELKARISASA------EELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
             + ++ ++++N EELK + + ++      E++   +   AEDV+  L G  +   K +  L
Sbjct  1646  QRIS-ELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENL  1704

Query  212   GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLE  263
                  ++  + RR+ E   +N  K L+ Q     Q L       E +  +LE
Sbjct  1705  IAKKTEESADARRKAEML-QNEAKTLLAQANSKLQLLKDLERKYEDNQRYLE  1755


>gi|1174915|sp|P46939|UTRO_HUMAN  Utrophin (Dystrophin-related protein 1) (DRP1) (DRP)
Length=3433

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 30/124 (24%), Positives = 59/124 (47%), Gaps = 5/124 (4%)

Query  43    KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHA  102
             K++ E  +K E    + + +Q ++ +A +  R L      ++  ++E A+S++   +P  
Sbjct  2663  KQSSEVKEKWESLNAVTSNWQKQVDKALEKLRDLQGAMDDLDADMKE-AESVRNGWKPVG  2721

Query  103   DELKAKIDQNVEELKGRLTPYAD-EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT  161
             D L   +  ++E++       A   FKVK   TV +L   L+P       K++ QL+ L 
Sbjct  2722  DLLIDSLQDHIEKIMAFREEIAPINFKVK---TVNDLSSQLSPLDLHPSLKMSRQLDDLN  2778

Query  162   FQMK  165
              + K
Sbjct  2779  MRWK  2782


 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 30/155 (19%), Positives = 67/155 (43%), Gaps = 10/155 (6%)

Query  103   DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF  162
             DE++ K     EE+  RL    D+  ++++   ++    +      ++E +  +L  L  
Sbjct  1676  DEIEKKPTSKQEEIVKRLVSELDDANLQVENVRDQALILMNARGSSSRELVEPKLAELNR  1735

Query  163   QMKKNAEELK-ARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL----GGHL--  215
               +K ++ +K A++  + E L Q L        G    + E L+  +  +      HL  
Sbjct  1736  NFEKVSQHIKSAKLLIAQEPLYQCLVTTETFETGVPFSDLEKLENDIENMLKFVEKHLES  1795

Query  216   ---DQQVEEFRRRVEPYGENFNKALVQQMEQLRQK  247
                D++++E   ++E   +   + L Q ME  +++
Sbjct  1796  SDEDEKMDEESAQIEEVLQRGEEMLHQPMEDNKKE  1830


>gi|400793|sp|Q00722|PLCB2_HUMAN  1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 
2 (Phosphoinositide phospholipase C) (Phospholipase C-beta-2) 
(PLC-beta-2)
Length=1181

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 31/165 (18%), Positives = 64/165 (38%), Gaps = 5/165 (3%)

Query  109   IDQNVEELKGRLT-----PYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
             +D  V ELK RL         ++++  + +  + +   ++   +  +EK   +L+ L   
Sbjct  972   VDGRVRELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKET  1031

Query  164   MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
              + + +E+K ++     E  Q +  +  D     R   E     + E+   + Q  E   
Sbjct  1032  SENDTKEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLE  1091

Query  224   RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD  268
             R  E   E     L Q  E  +Q       + E  +  LE ++++
Sbjct  1092  RHQEKLEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKE  1136


>gi|34925430|sp|Q9HCN4|XAB1_HUMAN  XPA-binding protein 1
Length=374

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 31/205 (15%)

Query  41   NAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRP  100
            N  + ++H    E  Q   A FQD L        Q T Y   + R +    D   +SLR 
Sbjct  189  NKTDIIDHSFAVEWMQDFEA-FQDALN-------QETTYVSNLTRSMSLVLDEFYSSLRV  240

Query  101  HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL  160
                + A +   ++EL  ++T  A+E++ +     E L++SLA  A+  Q++   QLE L
Sbjct  241  VG--VSAVLGTGLDELFVQVTSAAEEYEREYRPEYERLKKSLA-NAESQQQR--EQLERL  295

Query  161  TFQMKKNAEELKARISASAEELRQRLAPLAED-----VRGNLRGNTEGLQKSLAELGGHL  215
               M          ++  A   +  L+P+         RG L    E       ++   +
Sbjct  296  RKDM--------GSVALDAGTAKDSLSPVLHPSDLILTRGTLDEEDEEADSDTDDIDHRV  347

Query  216  DQQVEEFRRRVEPYGENFNKALVQQ  240
             ++  E     EP  +NF +  + Q
Sbjct  348  TEESHE-----EPAFQNFMQESMAQ  367


 Score = 32.0 bits (71),  Expect = 0.40
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query  182  LRQRLAPLAEDVRGNLR--GNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALV-  238
            L + ++ + ++   +LR  G +  L   L EL   +    EE+ R   P  E   K+L  
Sbjct  223  LTRSMSLVLDEFYSSLRVVGVSAVLGTGLDELFVQVTSAAEEYEREYRPEYERLKKSLAN  282

Query  239  -------QQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGEEGQS  287
                   +Q+E+LR+ +G  A D       L   L   +  L  G  DE  EE  S
Sbjct  283  AESQQQREQLERLRKDMGSVALDAGTAKDSLSPVLHPSDLILTRGTLDEEDEEADS  338


>gi|62287118|sp|Q96CV9|OPTN_HUMAN  Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting 
protein) (FIP-2) (Huntingtin-interacting protein HYPL) 
(NEMO-related protein) (Transcription factor IIIA-interacting 
protein) (TFIIIA-IntP)
Length=577

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 55/248 (22%), Positives = 110/248 (44%), Gaps = 40/248 (16%)

Query  54   LTQQLNALFQD------KLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKA  107
            L  Q+ +LF++      KL EAE ++++L    Q +ER  + +A   + + +        
Sbjct  302  LNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER--KNSAIPSELNEKQELVYTNK  359

Query  108  KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL----NHQLEGLTFQ  163
            K++  VE +           ++K++Q   E  +S     Q T  KL    N+ L+ +   
Sbjct  360  KLELQVESMLS---------EIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEEL  410

Query  164  MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR  223
             +K +E++     A  +EL ++L  LAE    + +   + +++++A+    L + +   R
Sbjct  411  TRKESEKVD---RAVLKELSEKL-ELAEKALASKQLQMDEMKQTIAKQEEDL-ETMTILR  465

Query  224  RRVEPYGENFN------KALVQQMEQLRQKLG-----PHAGDVEGHLSFLEKDLRDKNWG  272
             ++E Y  +F+      + + ++ EQL  +L        A +  G  S +E   R    G
Sbjct  466  AQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRH---G  522

Query  273  LRLGDRDE  280
             R  D D+
Sbjct  523  ARTSDSDQ  530


>gi|37537841|sp|Q9BXX0|EMIL2_HUMAN  EMILIN-2 precursor (Elastin microfibril interface-located protein 
2) (Elastin microfibril interfacer 2) (Protein FOAP-10)
Length=1053

 Score = 33.1 bits (74),  Expect = 0.18
 Identities = 34/177 (19%), Positives = 75/177 (42%), Gaps = 25/177 (14%)

Query  110  DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE  169
            +  ++++K  L    D  K K D+ +EEL   +  Y    ++ L    +G T  M  N E
Sbjct  256  ESGMKDIKSELAEVKDTLKNKSDK-LEELDGKVKGYEGQLRQ-LQEAAQGPTVTMTTN-E  312

Query  170  ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY  229
              +A + +  + LR+ L               EG+ + LA+L    + ++   +++ + Y
Sbjct  313  LYQAYVDSKIDALREELM--------------EGMDRKLADLKNSCEYKLTGLQQQCDDY  358

Query  230  GENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGEEGQ  286
            G ++   +        + +G     +   ++ L   L++ +      D +++G+ GQ
Sbjct  359  GSSYLGVI--------ELIGEKETSLRKEINNLRARLQEPSAQANCCDSEKNGDIGQ  407


>gi|74749713|sp|Q6ZWJ1|STXB4_HUMAN  Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip)
Length=553

 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 28/137 (20%), Positives = 68/137 (49%), Gaps = 23/137 (16%)

Query  24   ADQVATVMWDYFSQLSNNAKEAVEHL--QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQ  81
            A +++ ++        ++  + +E L  ++ +  +++N L ++KL E+++ R+QLT   Q
Sbjct  275  AHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTL-KEKLLESDKQRKQLTEELQ  333

Query  82   RME----------RVLRENADSLQASLRP------HADELKAKIDQNVEELKGRLTPYAD  125
             ++          R LR      +A+ R         +E+   ++  + ELK +L  Y+D
Sbjct  334  NVKQEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKITELKAQLADYSD  393

Query  126  EFKVKIDQTVEELRRSL  142
            + K    ++V++L++ +
Sbjct  394  QNK----ESVQDLKKRI  406


>gi|20138710|sp|Q9BW19|KIFC1_HUMAN  Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related 
protein HSET)
Length=673

 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 48/196 (24%), Positives = 81/196 (41%), Gaps = 33/196 (16%)

Query  32   WDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
            WD   QL +   E     ++++   Q N   QD+L +A+Q  + L               
Sbjct  137  WDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKAL---------------  181

Query  92   DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE  151
             + + +L  H  +++A+ +Q  +ELK  L     E + ++  T E L + L    Q  Q 
Sbjct  182  GTERTTLEGHLAKVQAQAEQGQQELK-NLRACVLELEERL-STQEGLVQEL----QKKQV  235

Query  152  KLNHQLEGLTFQMKKNAEEL---KARISASAEE---LRQRLAPLA------EDVRGNLRG  199
            +L  +  GL  Q+++    L   +A +S+S  E   LRQ     A      E+    L  
Sbjct  236  ELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEM  295

Query  200  NTEGLQKSLAELGGHL  215
                L   L EL G++
Sbjct  296  ERRRLHNQLQELKGNI  311


>gi|128147|sp|P07197|NFM_HUMAN  Neurofilament triplet M protein (160 kDa neurofilament protein) 
(Neurofilament medium polypeptide) (NF-M) (Neurofilament 
3)
Length=916

 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 36/221 (16%), Positives = 92/221 (41%), Gaps = 17/221 (7%)

Query  41   NAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA------DSL  94
            N ++A   L    L + ++ L +++  E  +LR       + + + + E +      D  
Sbjct  165  NHEKAQVQLDSDHLEEDIHRL-KERFEEEARLRDDTEAAIRALRKDIEEASLVKVELDKK  223

Query  95   QASLRPHADELKAKIDQNVEELKGRL------TPYADEFKVKIDQTVEELRRSLAPYAQD  148
              SL+     L++  ++ V +L  ++          D  K  I   ++E+R  L  ++  
Sbjct  224  VQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQ  283

Query  149  TQEKLNHQLEGLTFQMKKNAEELKARISASAEEL---RQRLAPLAEDVRGNLRGNTEGLQ  205
               +     +    ++ + AE+ K  I ++ EE+   R++L   + ++  ++RG  E L+
Sbjct  284  NMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELE-SVRGTKESLE  342

Query  206  KSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ  246
            + L+++    +  +  ++  ++           +    LR+
Sbjct  343  RQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLRE  383


>gi|13431284|sp|Q9UPM8|AP4E1_HUMAN  AP-4 complex subunit epsilon-1 (Adapter-related protein complex 
4 epsilon-1 subunit) (Epsilon subunit of AP-4) (AP-4 adapter 
complex epsilon subunit)
Length=1137

 Score = 32.7 bits (73),  Expect = 0.23
 Identities = 38/124 (30%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query  83   MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV-------  135
            +ER++ E   SL   +R HA ELK  + +NVE +K  L        + +D ++       
Sbjct  571  VERLIHEFTISLDTCMRQHAFELK-HLHENVELMKSLLPVDRSCEDLVVDASLSFLDGFV  629

Query  136  -EELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA--PLAED  192
             E L +  APY    Q     Q E L+ +   N E      S+S    RQ  A   L  D
Sbjct  630  AEGLSQGAAPYKPPHQ----RQEEKLSQEKVLNFEPYGLSFSSSGFTGRQSPAGISLGSD  685

Query  193  VRGN  196
            V GN
Sbjct  686  VSGN  689


>gi|56405385|sp|Q9HCM9|TRI39_HUMAN  Tripartite motif protein 39 (RING finger protein 23) (Testis-abundant 
finger protein)
Length=518

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query  126  EFKVKIDQTVEELRRSLAPYAQ--DTQEK----LNHQLEGLTFQMKKNAEELKARISASA  179
            E+K K+ + +E L + L    +   ++EK    L   +E    Q+ +  EEL  R+    
Sbjct  149  EYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQ  208

Query  180  EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE  220
            + L  RL    +D+   LR N   L     +L  HL  +VE
Sbjct  209  QVLLSRLEEEEQDILQRLRENAAHLGDKRRDL-AHLAAEVE  248


 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 10/115 (8%)

Query  83   MERVLRENADSLQASLRPHADELK--AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
            ++   +E  + LQ  L P   +L+   +   + E+  G L    +  + +I +  EEL R
Sbjct  143  LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR  202

Query  141  SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRG  195
             L    Q    +L  + + +  ++++NA  L         + R+ LA LA +V G
Sbjct  203  RLDEEQQVLLSRLEEEEQDILQRLRENAAHL--------GDKRRDLAHLAAEVEG  249


>gi|46396501|sp|Q9BRK4|LZTS2_HUMAN  Leucine zipper putative tumor suppressor 2 (Protein LAPSER1)
Length=669

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 51/211 (24%), Positives = 88/211 (41%), Gaps = 34/211 (16%)

Query  36   SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
            +Q +  A++ ++ LQ  +L Q+   L QD   +  Q R QL      +ER  RE      
Sbjct  380  AQRAQRAQQLLQ-LQVFQLQQEKRQL-QDDFAQLLQEREQLERRCATLEREQRE------  431

Query  96   ASLRPHADELKAKI----------DQNVEELKGRLTPYADEFKVKIDQTVEELRRSL---  142
              L P  +E K ++           Q ++E +  L     E  V +   + E R +L   
Sbjct  432  --LGPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSEL-VALRVALREARATLRVS  488

Query  143  ---APYAQDTQEKLNHQLEGLTFQMKKNAEELK------ARISASAEELRQRLAPLAEDV  193
               A   Q+       +LE  + +++++ +E +       ++ A A  LR+   P A   
Sbjct  489  EGRARGLQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATAD  548

Query  194  RGNLRGNTEG-LQKSLAELGGHLDQQVEEFR  223
               L  + E  +Q++ A +GG L  QVE  R
Sbjct  549  PFLLAESDEAKVQRAAAGVGGSLRAQVERLR  579


>gi|20137431|sp|Q99941|ATF6B_HUMAN  Cyclic AMP-dependent transcription factor ATF-6 beta (Activating 
transcription factor 6 beta) (ATF6-beta) (cAMP-responsive 
element binding protein-like 1) (cAMP response element-binding 
protein-related protein) (Creb-rp) (G13 protein)
Length=703

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 0/55 (0%)

Query  38   LSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD  92
            + N         +K E  Q L A  Q  L + +QLRR+     +R+E +L EN++
Sbjct  333  IKNRESACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLAENSE  387


>gi|74732524|sp|Q96NA2|RILP_HUMAN  Rab-interacting lysosomal protein
Length=401

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 52/225 (23%), Positives = 89/225 (39%), Gaps = 36/225 (16%)

Query  76   LTPYAQRMERVLRENA-----DSLQASLRPHADELKAKIDQNVEELKGRLTPYADE----  126
            L P   R   +L + A     DSLQ S +P   EL+   ++N E L+  L     E    
Sbjct  54   LVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREEN-ERLRRELRAGPQEERAL  112

Query  127  ---FKVKIDQTVEELR---RSLAPYAQDTQEKLNHQLEGLTF---QMKKNAEELKARISA  177
                K   D+  +ELR   R L    Q+T E L  QL+ L     +++     ++ ++ A
Sbjct  113  LRQLKEVTDRQRDELRAHNRDLRQRGQET-EALQEQLQRLLLVNAELRHKLAAMQTQLRA  171

Query  178  SAEELRQRLAP-------LAEDVRGNL--RGNTEGLQKSLAELGGHLDQQVEEFRRRVEP  228
            + +  R+R  P         E  RG     G+  G +   A  G       E+     + 
Sbjct  172  AQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQ  231

Query  229  YGE-------NFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL  266
             G         F++   +Q+ Q R +L      ++  L++ +++L
Sbjct  232  LGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQREL  276


>gi|2497600|sp|Q13751|LAMB3_HUMAN  Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k 
chain) (Kalinin B1 chain)
Length=1172

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 54/251 (21%), Positives = 100/251 (39%), Gaps = 31/251 (12%)

Query  69    AEQLR--RQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGR--LTPYA  124
             AEQLR         ++M R   E+A  +Q+S +    ++ A   Q  E+++    L    
Sbjct  836   AEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQV  895

Query  125   DEFKVKIDQ---TVEELRRSLAPYAQDTQ-----EKLNH------QLEGLTFQMKKNAEE  170
              +F    D    T++E+  ++      T      +K+N       +L  +   + +  ++
Sbjct  896   RDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQD  955

Query  171   LKA--RISASAEELRQRLAPL---AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR  225
             +    R+ A AEE R R   +    EDV GNLR  T  LQ++   + G   + +   + R
Sbjct  956   IARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQG-TSRSLRLIQDR  1014

Query  226   VEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRDESGEEG  285
             V        + +++  E+L   +    GD    +  L    R +  G       +  E  
Sbjct  1015  VAEV-----QQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQ--GAEAVQAQQLAEGA  1067

Query  286   QSRGMQALQGF  296
               + + A +GF
Sbjct  1068  SEQALSAQEGF  1078


 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 2/103 (1%)

Query  24    ADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRM  83
             A + A    + F ++     E  + L +S +  +  A  Q    EAE+L  +      RM
Sbjct  1067  ASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRM  1126

Query  84    ERVLRENADSLQASLRPHAD--ELKAKIDQNVEELKGRLTPYA  124
             + +  E     QA +   AD   L+ +++Q  + + GR+  YA
Sbjct  1127  KDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYA  1169


>gi|134973|sp|P16949|STMN1_HUMAN  Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) 
(Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) 
(Protein Pr22)
Length=149

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 0/79 (0%)

Query  169  EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP  228
            EE++ ++ A+ E  +   A + + +        E LQK++ E         E+   ++E 
Sbjct  48   EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA  107

Query  229  YGENFNKALVQQMEQLRQK  247
              EN    +  ++E+LR+K
Sbjct  108  NKENREAQMAAKLERLREK  126


>gi|12643814|sp|Q9NQ66|PLCB1_HUMAN  1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 
1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) 
(PLC-beta-1) (PLC-I) (PLC-154)
Length=1216

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 43/242 (17%), Positives = 101/242 (41%), Gaps = 20/242 (8%)

Query  25    DQVATVMWDYFSQLSNNAKE--AVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQR  82
             D + +V+ +  +Q     K+  +   LQK    +  + + +      + ++   T Y + 
Sbjct  896   DLIQSVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEI  955

Query  83    MERVLRENA--------DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQT  134
                 LR  A        DS + S     D   + I+Q++  L   +T    + K K  Q 
Sbjct  956   QNDYLRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQ  1015

Query  135   VEELRRSLAPYAQDTQEKLNH------QLEGLTFQMKKNA-EELKARISASAEELRQRLA  187
             +  LR+    Y  +  +K  H      +L  +  + + N  ++LK       +EL++++ 
Sbjct  1016  LLNLRQE--QYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMD  1073

Query  188   PLAEDVRGNLRGNTEG-LQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ  246
                ++     +   +  +++   E+     Q+V ++ +R+E       + LV++ +++RQ
Sbjct  1074  KKRQEKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQ  1133

Query  247   KL  248
             ++
Sbjct  1134  QI  1135


>gi|12230855|sp|Q99543|ZRF1_HUMAN  Zuotin-related factor 1 (M-phase phosphoprotein 11)
Length=568

 Score = 32.3 bits (72),  Expect = 0.30
 Identities = 41/180 (22%), Positives = 70/180 (38%), Gaps = 17/180 (9%)

Query  32   WDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
            W  FS L    KE  E   +    ++ N   + +  + E  R           R L +NA
Sbjct  224  WREFSYLDEEEKEKAECRDERRWIEKQNGATRAQRKKEEMNRI----------RTLVDNA  273

Query  92   DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS-LAPYAQDTQ  150
             S    ++   +E KAK +    E K +      E + K  Q   EL  + LA   ++ +
Sbjct  274  YSCDPRIKKFKEEEKAKKEA---EKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEEEE  330

Query  151  EKLNHQLEGLTFQMKKNA---EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS  207
             +    L      ++K A   E  K R S   EE+ +++    E+    +R  ++  +KS
Sbjct  331  VRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTEKS  390


>gi|62511032|sp|Q6UVJ0|SAS6_HUMAN  Spindle assembly abnormal protein 6 homolog (HsSAS-6)
Length=657

 Score = 32.0 bits (71),  Expect = 0.40
 Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 19/231 (8%)

Query  50   QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL---K  106
            +K  L Q L+    D   + +  R+ L    Q ++++  E A    A    H+ EL   K
Sbjct  163  EKLSLMQSLD----DATKQLDFTRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEK  218

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
             K  Q   + + +      + ++   Q + +L+  L+       E  N  L    ++   
Sbjct  219  EKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL-----EAANKDLTERKYKGDS  273

Query  167  NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK-----SLAELGGHLDQQVEE  221
               ELKA++S   EEL++    +    R N   + E  +K      L      L+Q++++
Sbjct  274  TIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHVNQLQTKVAVLEQEIKD  333

Query  222  FRRRVEPYGENFNKALVQQ--MEQLRQKLGPHAGDVEGHLSFLEKDLRDKN  270
              + V    E F+    Q+  +E+  +K     G +E  +  L  +L   N
Sbjct  334  KDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLSAELLKAN  384


>gi|10720353|sp|O15078|CE290_HUMAN  Centrosomal protein Cep290
Length=1539

 Score = 32.0 bits (71),  Expect = 0.40
 Identities = 50/217 (23%), Positives = 90/217 (41%), Gaps = 38/217 (17%)

Query  48    HLQKSELTQQLNAL----FQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD  103
             HLQ   L ++L+AL     +D   +      +   + QR + + +EN      ++     
Sbjct  1079  HLQNRYLQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQELQKENLKLSSENI-----  1133

Query  104   ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNH--------  155
             ELK +++Q  ++L  RL     + K    +  E L++  A    + Q KL H        
Sbjct  1134  ELKFQLEQANKDLP-RLKNQVRDLK----EMCEFLKKEKA----EVQRKLGHVRGSGRSG  1184

Query  156   ----QLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL  211
                 +LE     MKK  E    ++    E+L++    L  +   N+    E L+  L +L
Sbjct  1185  KTIPELEKTIGLMKKVVE----KVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKL  1240

Query  212   GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL  248
               HL  Q+       E   +   K ++ + E+LR++L
Sbjct  1241  KAHLGHQLS---MHYESKTKGTEK-IIAENERLRKEL  1273


>gi|48428272|sp|Q9UIF7|MUTYH_HUMAN  A/G-specific adenine DNA glycosylase (MutY homolog) (hMYH)
Length=546

 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query  176  SASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYG  230
            SAS EE+ Q  A L    RG  R   EG +K + ELGGH+ +  E  ++ +   G
Sbjct  161  SASLEEVNQLWAGLGYYSRG--RRLQEGARKVVEELGGHMPRTAETLQQLLPGVG  213


>gi|71153185|sp|Q9UPW8|UN13A_HUMAN  Unc-13 homolog A (Munc13-1)
Length=1703

 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 36/186 (19%), Positives = 76/186 (40%), Gaps = 21/186 (11%)

Query  33    DYFSQLSNNAKEAVEHLQK-SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENA  91
             D F Q S +A  +   +   S+L Q    + + +  + + +   +  +A+ +  VL + A
Sbjct  1174  DGFQQTSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYA  1233

Query  92    DSLQASLRPHADELKAKID----QNVEELKGRLTPYAD----------------EFKVKI  131
             D +      +  + K K+      N ++L+ +L    +                E +VK+
Sbjct  1234  DIISKDFASYCSKEKEKVPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKELQVKL  1293

Query  132   DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE  191
             +  ++EL R  A   Q   E+   Q+  +  Q+K       +  S+ A++    L P+ +
Sbjct  1294  NNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMD  1353

Query  192   DVRGNL  197
              +  NL
Sbjct  1354  LLDSNL  1359


>gi|25090171|sp|Q8TEK3|DOT1L_HUMAN  Histone-lysine N-methyltransferase, H3 lysine-79 specific (Histone 
H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein)
Length=1739

 Score = 31.6 bits (70),  Expect = 0.52
 Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 21/168 (12%)

Query  55   TQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVE  114
            T Q  A  Q+ LG+ ++   QL   AQ+           L +  +   +E++    Q ++
Sbjct  504  TPQYKASLQELLGQEKEKNAQLLGAAQQ-----------LLSHCQAQKEEIRRLFQQKLD  552

Query  115  ELKGRLTPYAD--EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ-MKKNAEEL  171
            EL  +   Y D  + + +I    ++LR       QD     N  L G + Q +K   EEL
Sbjct  553  ELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQD-----NRALRGQSLQLLKARCEEL  607

Query  172  KAR-ISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
            +    + S E+L +    L   +    R   E LQ S+ EL     QQ
Sbjct  608  QLDWATLSLEKLLKEKQALKSQISEKQRHCLE-LQISIVELEKSQRQQ  654


>gi|23396625|sp|Q9NQT8|KI13B_HUMAN  Kinesin-like protein KIF13B (Kinesin-like protein GAKIN)
Length=1826

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 35/155 (22%), Positives = 72/155 (46%), Gaps = 17/155 (10%)

Query  33   DYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLR--EN  90
            D    + N+ ++  E  ++S L +Q   +++ +L   EQLRR+L+P  Q    + R   +
Sbjct  605  DPMQSILNSLEQQHEEEKRSALERQ-RLMYEHEL---EQLRRRLSPEKQNCRSMDRFSFH  660

Query  91   ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ  150
            + S Q  LR  A+E +A ++ ++  L+ ++        VK +  V E         + T+
Sbjct  661  SPSAQQRLRQWAEEREATLNNSLMRLREQI--------VKANLLVREANYIAEELDKRTE  712

Query  151  EKLNHQLEGLTFQMKKNAEELKARISASAEELRQR  185
             K+  Q+   +    +    L   +S  A ++R++
Sbjct  713  YKVTLQIPASSLDANRKRGSL---LSEPAIQVRRK  744


>gi|23503075|sp|P08779|K1C16_HUMAN  Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) 
(K16)
Length=473

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 10/126 (7%)

Query  26   QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMER  85
            ++   M D + Q++   +   E    S+ T++LN          +  R ++T     + R
Sbjct  284  RILNEMRDQYEQMAEKNRRDAETWFLSK-TEELNKEVASNSELVQSSRSEVT----ELRR  338

Query  86   VLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY  145
            VL+     LQ+ L      +KA ++ ++EE KGR      + +  I    E+L +     
Sbjct  339  VLQGLEIELQSQL-----SMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEM  393

Query  146  AQDTQE  151
             Q +QE
Sbjct  394  EQQSQE  399


>gi|6016414|sp|Q14532|K1H2_HUMAN  Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2)
Length=448

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI---DQNVEELKGRLT-PY  123
            EAE   RQL        R + ++    +A L    + LK ++    +N EE  G L    
Sbjct  186  EAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQL  245

Query  124  ADEFKVKID--------QTVEELRRSLAPYAQ----DTQEKLNHQLEGLTFQMKKNAEEL  171
             D   +++D        + +EE+R       +    D +E  N Q+E L  Q+  ++E+L
Sbjct  246  GDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQL  305

Query  172  KARISASAEELRQRLAPLAEDVRG--NLRGNTEG-LQKSLAELGGHLDQ----------Q  218
            +    +   +LR+ +  L  +++   +LR + E  L +S A     L Q          Q
Sbjct  306  Q-NYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQ  364

Query  219  VEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKD  265
            + E R  +E   + +     Q +  +R +L    G++  + S LE +
Sbjct  365  LAEIRAELERQNQEY-----QVLLDVRARL---EGEINTYRSLLESE  403


>gi|48475013|sp|Q9UMX0|UBQL1_HUMAN  Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) 
(hPLIC-1)
Length=589

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 8/70 (11%)

Query  50   QKSELTQQL---NALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
            Q  +L  Q+   N LF       EQ+R+QL  + Q+M     +N D+L A   P A +  
Sbjct  409  QNPDLAAQMMLNNPLFAGNPQLQEQMRQQLPTFLQQM-----QNPDTLSAMSNPRAMQAL  463

Query  107  AKIDQNVEEL  116
             +I Q ++ L
Sbjct  464  LQIQQGLQTL  473


>gi|50403793|sp|Q96L93|SNX23_HUMAN  Kinesin-like motor protein C20orf23 (Sorting nexin 23)
Length=1317

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 56/236 (23%), Positives = 106/236 (44%), Gaps = 38/236 (16%)

Query  43   KEAVEHLQKSELTQQLNA-LFQDKLGEAEQ-LRRQLTPYAQRMERVLRENADSLQASLRP  100
            K  +E +Q+   TQ+    + Q ++ + E+ L+R+      +++ +L E     +  LR 
Sbjct  627  KAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLRE  686

Query  101  HAD-ELKAKIDQN-----VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
              + EL+ K  +      V+E   RL    +  K +  Q  +EL           Q++ +
Sbjct  687  QQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQEL--------DQLQKEKD  738

Query  155  HQLEGLTFQMKKNAEELKARISASA---EELRQRLAPLAEDVRGNL------RGNTEGLQ  205
             Q   L  + K+  E+ K ++   A   E+LR++   +    RG +      + + EG++
Sbjct  739  EQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIR  798

Query  206  KSL-----AELGGHLD-QQVE-------EFRRRVEPYGENFNKALVQQMEQLRQKL  248
            +SL     A  GG  D +++E       EF+RR      N  K LVQQ + L++++
Sbjct  799  ESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEV  854


>gi|13431713|sp|Q9NQX4|MYO5C_HUMAN  Myosin-5C (Myosin Vc)
Length=1742

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 55/251 (21%), Positives = 98/251 (39%), Gaps = 47/251 (18%)

Query  46    VEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENAD------SLQASLR  99
             VE +QK E   +L      +    E+ +R      +++ ++ + N++       +Q  L+
Sbjct  923   VEKIQKLEA--ELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQ  980

Query  100   PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
                +ELK K+D   ++L               D   EE +R L          L    E 
Sbjct  981   EKTEELKEKMDNLTKQLFD-------------DVQKEERQRML----------LEKSFEL  1017

Query  160   LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQV  219
              T   +K  + LK  I A  +E  Q    L   V G     ++GL+  +A L   + + +
Sbjct  1018  KTQDYEKQIQSLKEEIKALKDEKMQ----LQHLVEGE-HVTSDGLKAEVARLSKQV-KTI  1071

Query  220   EEFRRRVE---PYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK-DLRDKNWGLRL  275
              EF + +E       +  K +  Q  ++R+K+       E     LE  D+ D    L +
Sbjct  1072  SEFEKEIELLQAQKIDVEKHVQSQKREMREKMS------EITKQLLESYDIEDVRSRLSV  1125

Query  276   GDRDESGEEGQ  286
              D +   E+G+
Sbjct  1126  EDLEHLNEDGE  1136


>gi|29427585|sp|O95819|M4K4_HUMAN  Mitogen-activated protein kinase kinase kinase kinase 4 (MAPK/ERK 
kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) 
(HPK/GCK-like kinase HGK) (Nck-interacting kinase)
Length=1239

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 50/226 (22%), Positives = 94/226 (41%), Gaps = 24/226 (10%)

Query  35   FSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL  94
            F +L    KE  E L++ +L Q+       +L E E+ +RQL    Q+     +E    L
Sbjct  356  FLRLQQENKERSEALRRQQLLQE------QQLREQEEYKRQLLAERQKRIEQQKEQRRRL  409

Query  95   QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN  154
            +   R    E +A+  Q  E+ +          +++  +  EE RR     A++ + ++ 
Sbjct  410  EEQQR---REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR----AEEEKRRVE  462

Query  155  HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN--TEGLQKSLAELG  212
             + E     +++  EE +  +    ++L Q  A L E     +  +   E LQ+ L +  
Sbjct  463  REQE----YIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQ  518

Query  213  GHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGH  258
             +L     + RR   P+ ++  +    Q E  R K   HA + + H
Sbjct  519  AYLLSLQHDHRR---PHPQHSQQPPPPQQE--RSKPSFHAPEPKAH  559


>gi|71153214|sp|Q68D86|CR014_HUMAN  Hypothetical protein C18orf14
Length=513

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 27/111 (24%), Positives = 53/111 (47%), Gaps = 11/111 (9%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTP---YA  124
            E  QLR +L    + +  + ++       SL P  + L+A + Q+++ L G +     + 
Sbjct  119  EGRQLRIKLEMATKELSTLKKKQ------SLPPQKEALEANVTQDLK-LPGFVEESCEHT  171

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARI  175
            D+F++   Q  E +R  L      T+E  N++ +G+     K +EE+K  +
Sbjct  172  DQFQLS-SQMHESIREYLVKRQFSTKEDTNNKEQGVVIDSLKLSEEMKPNL  221


>gi|6175045|sp|Q13277|STX3_HUMAN  Syntaxin-3
Length=289

 Score = 31.2 bits (69),  Expect = 0.68
 Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 18/145 (12%)

Query  98   LRPHADELKAKI-----DQNVEELKGRLTPYADEFKVKIDQT----------VEELRR--  140
            ++   ++LKAK      D +  E+    T + DEF  +I++T          VEE ++  
Sbjct  1    MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY  60

Query  141  SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN  200
            S+   A   + K    LE LT ++KK A  ++ ++ +  + + +     + D+R   +  
Sbjct  61   SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIR-KSQ  119

Query  201  TEGLQKSLAELGGHLDQQVEEFRRR  225
               L +   E+    ++   +FR R
Sbjct  120  HSVLSRKFVEVMTKYNEAQVDFRER  144


>gi|38605459|sp|Q9C035|TRIM5_HUMAN  Tripartite motif protein 5 (RING finger protein 88)
Length=493

 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 26/119 (21%), Positives = 47/119 (39%), Gaps = 5/119 (4%)

Query  124  ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR  183
            A E++VK+   +E LR+      Q   E+L   +       K   +  K  + A  E+LR
Sbjct  135  AREYQVKLQAALEMLRQK-----QQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR  189

Query  184  QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME  242
              L     +   NL    E + KSL      + QQ +  R  +         ++++ ++
Sbjct  190  DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQ  248


 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 25/122 (20%), Positives = 52/122 (42%), Gaps = 6/122 (4%)

Query  54   LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNV  113
            LT+++   +Q KL  A ++ RQ    A+ +E  +RE   S +  ++     + A  +Q  
Sbjct  130  LTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR  189

Query  114  EELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ------EKLNHQLEGLTFQMKKN  167
            + L    +      + + +  ++ L  S     Q TQ        L H+L+G   ++ + 
Sbjct  190  DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQG  249

Query  168  AE  169
             +
Sbjct  250  VD  251


>gi|13959419|sp|Q9UJF2|NGAP_HUMAN  Ras GTPase-activating protein nGAP (RAS protein activator-like 
1)
Length=1139

 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 34/143 (23%), Positives = 68/143 (47%), Gaps = 15/143 (10%)

Query  110   DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE  169
             +QN++E K     +A++++ +I +  E LR S         E+   +L     QM+K   
Sbjct  977   EQNLDEAK-----HAEKYEQEITKLKERLRVS-----SRRLEEYERRLLVQEQQMQKLLL  1026

Query  170   ELKARISASAEELRQRLAPLAEDVR---GNLRGNTEGLQKSLAELGGHLD--QQVEEFRR  224
             E KAR+  S E LR++       ++     L    E L+K  AE+   +D  Q++ + + 
Sbjct  1027  EYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQE  1086

Query  225   RVEPYGENFNKALVQQMEQLRQK  247
             +     ++ N  L+  + Q++++
Sbjct  1087  KRIVSLDSANTRLMSALTQVKER  1109


>gi|47606049|sp|Q9H5N1|RABE2_HUMAN  Rab GTPase-binding effector protein 2 (Rabaptin-5beta)
Length=569

 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 28/166 (16%)

Query  67   GEAEQLRRQLTPYAQRME--RVLRENADS--------LQASLRPHADELKAKIDQNVEEL  116
            GE  +LR +L      ME  + + E ++S        +Q   +     L+A +  ++   
Sbjct  38   GELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSY  97

Query  117  KGRLTPYADEFKVKIDQTVEELRRSLA--------PYAQDTQEKL-------NHQLEGLT  161
            + ++T    E + +  Q  EE  R L          Y  D+ EK        + +L  + 
Sbjct  98   EAQITALKQE-RQQQQQDCEEKERELGRLKQLLSRAYPLDSLEKQMEKAHEDSEKLREIV  156

Query  162  FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS  207
              M+K  EELKA++   AEEL Q +         +L G+TE L  S
Sbjct  157  LPMEKEIEELKAKL-LRAEELIQEIQRRPRHA-PSLHGSTELLPLS  200


>gi|22096362|sp|P54252|ATX3_HUMAN  Ataxin-3 (Machado-Joseph disease protein 1) (Spinocerebellar 
ataxia type 3 protein)
Length=376

 Score = 30.8 bits (68),  Expect = 0.89
 Identities = 19/86 (22%), Positives = 45/86 (52%), Gaps = 3/86 (3%)

Query  164  MKKNAEELKARISASAEEL--RQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE  221
            + ++ E+L+  ++ S +E+      A L   ++ +++G++  + + + +  G  +   EE
Sbjct  222  LDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSG-TNLTSEE  280

Query  222  FRRRVEPYGENFNKALVQQMEQLRQK  247
             R+R E Y E   +   QQ +Q +Q+
Sbjct  281  LRKRREAYFEKQQQKQQQQQQQQQQQ  306


>gi|34098604|sp|Q8TD16|BICD2_HUMAN  Cytoskeleton-like bicaudal D protein homolog 2
Length=824

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 18/121 (14%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF  127
            E +QLR  LT            N  S    L   A ELK +I+QNVE  +GRL     E+
Sbjct  124  ELKQLRNVLT------------NTQSENERLASVAQELK-EINQNVEIQRGRLRDDIKEY  170

Query  128  K---VKIDQTVEELRRSLAPYAQDTQEKLNHQL--EGLTFQMKKNAEELKARISASAEEL  182
            K    ++ Q   EL        +       +Q+  EGL  ++K+  EE +   S   + +
Sbjct  171  KFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAI  230

Query  183  R  183
            R
Sbjct  231  R  231


>gi|20455324|sp|Q9H2D6|TARA_HUMAN  TRIO and F-actin binding protein (Protein Tara) (Trio-associated 
repeat on actin)
Length=593

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 46/210 (21%), Positives = 89/210 (42%), Gaps = 32/210 (15%)

Query  39   SNNAKEAVEHLQKSELTQ------QLNALFQDKLGEAEQLRRQLTPYAQRME--RVLREN  90
            ++  ++A+++++ S LTQ      +  A   D+L + E+L R L   AQR E  R   E 
Sbjct  164  ADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDL---AQRSEERRKWFEA  220

Query  91   ADSLQASL-----------RPHADELKAKIDQNVEELKGRLT--PYADEFKVKIDQTVEE  137
             DS    +            P  ++ + ++ + +E+    L   P  +  +V +   + +
Sbjct  221  TDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQ  280

Query  138  LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL  197
             R        D  E L  +++ L  Q++    + +A  SA   +    + P      G +
Sbjct  281  SRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGHIPP------GYI  334

Query  198  RGNTEGLQKSLAELGGHLDQQVEEFRRRVE  227
              + E  ++SLAE+     Q +EE +R  E
Sbjct  335  --SQEACERSLAEMESSHQQVMEELQRHHE  362


>gi|41688524|sp|Q9UMD9|COHA1_HUMAN  Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 
kDa bullous pemphigoid antigen 2)
Length=1497

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 8/79 (10%)

Query  126  EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL---  182
            + K ++D+ +E +RRS+ PY          +L+G+      + +++    S S EEL   
Sbjct  494  KLKARVDE-LERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGLH-SDSQEELWMF  551

Query  183  -RQRLAPLAEDVRGNLRGN  200
             R++L  + E   GNLRG+
Sbjct  552  VRKKL--MMEQENGNLRGS  568


 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 11/50 (22%), Positives = 24/50 (48%), Gaps = 0/50 (0%)

Query  65   KLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVE  114
            ++ E E++RR + PY   M+R+ ++    +  +     D++    D   E
Sbjct  498  RVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGLHSDSQEE  547


>gi|20455319|sp|Q92994|TF3B_HUMAN  Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) 
(B-related factor 1) (BRF-1) (hBRF) (TATA box-binding protein-associated 
factor, RNA polymerase III, subunit 2) (TAF3B2)
Length=677

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 21/96 (21%), Positives = 48/96 (50%), Gaps = 5/96 (5%)

Query  104  ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ  163
            +L+  + + +EE++G ++ Y D  +++++ +  + +  LA  A+D   +       L  +
Sbjct  305  QLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTE--DTASSLCGE  362

Query  164  MKKNAEELKARISASAEELRQRL---APLAEDVRGN  196
                 EEL+A  S   ++L + L   AP + +  G+
Sbjct  363  EDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGS  398


>gi|134461|sp|P05060|SCG1_HUMAN  Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin 
B) (CgB) [Contains: GAWK peptide; CCB peptide]
Length=677

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query  137  ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGN  196
            E R+ L    +D ++K   + E   F+++   +   A  +  +    +  AP  ED++G 
Sbjct  56   ECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGP  115

Query  197  LRGNTEGLQKSLAELGGHLDQQVEE  221
             + +TE      AE GGH  ++ +E
Sbjct  116  TKADTE----KWAEGGGHSRERADE  136


>gi|50400772|sp|Q8N4C6|NIN_HUMAN  Ninein (hNinein)
Length=2090

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 40/187 (21%), Positives = 73/187 (39%), Gaps = 25/187 (13%)

Query  56   QQLNALFQDKLGEAEQLR--------RQLTPYAQRMERVLRENADSLQASLRPHADELKA  107
            +QL +L +    E E+LR        R+L    ++ME         ++A  +    ++  
Sbjct  768  EQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQSDCQKVTE  827

Query  108  KIDQNVEELKGRLTPYADEFKVKIDQTVEEL------RRSLAPYAQDTQEKLNHQLEG--  159
            + +  ++ L+GR   Y  E K   +Q  EE       +  L     + QE L   L+   
Sbjct  828  RCESALQSLEGR---YRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELLKETLKREK  884

Query  160  -----LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH  214
                 LT + +   +  K  +++   E RQ+L    ED+R         L   + EL   
Sbjct  885  TTSLVLTQEREMLEKTYKEHLNSMVVE-RQQLLQDLEDLRNVSETQQSLLSDQILELKSS  943

Query  215  LDQQVEE  221
              +++ E
Sbjct  944  HKRELRE  950


>gi|30316105|sp|Q96PK2|MACF4_HUMAN  Microtubule-actin crosslinking factor 1, isoform 4
Length=5938

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query  111   QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE  170
             Q  E+LK  +     E K ++D    +++  ++ +AQD   + N Q+  L  +++++ ++
Sbjct  1964  QQYEDLKQPMA----ERKAQLDALAFDIQFFISEHAQDLSPQQNRQMLRLLNELQRSFQD  2019

Query  171   LKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE  221
             +  + +A  + L+  L  + +          E L K+L +      QQ+E+
Sbjct  2020  ILEQTAAQVDALQGHLQQMEQ----------EALVKTLQKQQNTCHQQLED  2060


>gi|68566185|sp|Q6PKC3|TXD11_HUMAN  Thioredoxin domain-containing protein 11 (EF-hand-binding protein 
1)
Length=985

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 14/36 (38%), Positives = 22/36 (61%), Gaps = 0/36 (0%)

Query  55   TQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLREN  90
            ++QL AL++ K  E ++L R+L   A   E +L EN
Sbjct  883  SEQLQALYEQKTRELQELARKLQELADASENLLTEN  918


>gi|73620945|sp|O94833|BPAEA_HUMAN  Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) 
(Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque 
protein) (Dystonia musculorum protein) (Dystonin)
Length=5171

 Score = 30.4 bits (67),  Expect = 1.2
 Identities = 19/84 (22%), Positives = 44/84 (52%), Gaps = 4/84 (4%)

Query  70    EQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKV  129
             E+L++ +   AQ +  V++   + L+ +    + E KA I+Q + E K +     ++  +
Sbjct  1275  EELQKDMQGSAQALAEVVKNTENFLKENGEKLSQEDKALIEQKLNEAKIK----CEQLNL  1330

Query  130   KIDQTVEELRRSLAPYAQDTQEKL  153
             K +Q+ +EL + +    ++  EK+
Sbjct  1331  KAEQSKKELDKVVTTAIKEETEKV  1354


>gi|74753268|sp|Q9UDT6|CYLN2_HUMAN  Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) 
(CLIP-115) (Williams-Beuren syndrome chromosome region 4 protein)
Length=1046

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 39/148 (26%)

Query  81   QRMERVLRE-----------NADSLQASLRPHADE---LKAKIDQNVEELKGRLTPYADE  126
            QR   VLR+             D L+A+   +A E   LK K+ Q   E  G +    D 
Sbjct  557  QRESGVLRDKYEKALKAYQAEVDKLRAANEKYAQEVAGLKDKVQQATSENMGLM----DN  612

Query  127  FKVKIDQTVEELRRSL---------APYAQDTQ----------EKLNHQLEGLTFQMKKN  167
            +K K+D    + ++SL          P AQ  +           K+ HQLE    Q K +
Sbjct  613  WKSKLDSLASDHQKSLEDLKATLNSGPGAQQKEIGELKAVMEGIKMEHQLELGNLQAKHD  672

Query  168  AEELKARISASAEELRQRLAPLAEDVRG  195
             E   A      E LR++L    E++ G
Sbjct  673  LE--TAMHVKEKEALREKLQEAQEELAG  698


>gi|2501092|sp|Q13190|STX5_HUMAN  Syntaxin-5
Length=301

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 37/194 (19%), Positives = 80/194 (41%), Gaps = 15/194 (7%)

Query  49   LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAK  108
            L+K  +  +  +LF DK  E E+L   +      + + + +  D ++A        L+  
Sbjct  58   LEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTH  117

Query  109  IDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL-------NHQLEGLT  161
             +  V  L+ +L   +++FK  ++   E L++  +   Q ++  +       NH   G  
Sbjct  118  SNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAV  177

Query  162  FQMKKNAEELKARISASAEELRQRLAPLAE-DVRGNLRGNT-EGLQKSLAELG------G  213
                ++       I        Q+L  + E D     R +T + ++ ++ ELG       
Sbjct  178  VLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLA  237

Query  214  HLDQQVEEFRRRVE  227
            H+ ++ EE  +R++
Sbjct  238  HMVKEQEETIQRID  251


>gi|61247587|sp|Q969G3|SMCE1_HUMAN  SWI/SNF-related matrix-associated actin-dependent regulator of 
chromatin subfamily E member 1 (BRG1-associated factor 57)
Length=411

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 12/138 (8%)

Query  85   RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP  144
            +VL+    SL    R    EL  +I++  +E K +     D F         EL+R    
Sbjct  225  QVLKRQVQSLMVHQRKLEAEL-LQIEERHQEKKRKFLESTDSFN-------NELKRLCGL  276

Query  145  YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDV--RGNLRGNTE  202
              +   EK+  ++     Q +K  EE +   +  AE  +  + P  E    +G  + + E
Sbjct  277  KVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDE  336

Query  203  GLQKSLAELGGHLDQQVE  220
             +     E   HL++  E
Sbjct  337  NIPMETEET--HLEETTE  352


>gi|123408|sp|P28069|PIT1_HUMAN  Pituitary-specific positive transcription factor 1 (Pit-1) (Growth 
hormone factor 1) (GHF-1)
Length=291

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 9/151 (5%)

Query  91   ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKV---KIDQTVEELRRSLAP-YA  146
            A   +  LR  +  ++  ID +  E++  L  +A+EFKV   K+  T   +  +LA  + 
Sbjct  104  AADFKQELRRKSKLVEEPIDMDSPEIR-ELEKFANEFKVRRIKLGYTQTNVGEALAAVHG  162

Query  147  QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK  206
             +  +    + E L    K NA +LKA +S   EE  Q  A   E V  N R        
Sbjct  163  SEFSQTTICRFENLQLSFK-NACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTI  221

Query  207  SLA---ELGGHLDQQVEEFRRRVEPYGENFN  234
            S+A    L  H  +Q +   + +    E  N
Sbjct  222  SIAAKDALERHFGEQNKPSSQEIMRMAEELN  252


>gi|68846601|sp|O60664|M6PBP_HUMAN  Mannose-6-phosphate receptor-binding protein 1 (Cargo selection 
protein TIP47) (47 kDa mannose 6-phosphate receptor-binding 
protein) (47 kDa MPR-binding protein) (Placental protein 
17) (PP17)
Length=434

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 18/159 (11%)

Query  81   QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV---EE  137
            QR E+       SL   LR HA E       ++ +L+      A E  +++ Q +   E 
Sbjct  229  QRQEQSYFVRLGSLSERLRQHAYE------HSLGKLRAT-KQRAQEALLQLSQALSLMET  281

Query  138  LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAEDVRG  195
            +++ +     + QEKL HQ+      +  N ++L+   +     E++  R   +  D+  
Sbjct  282  VKQGVDQKLVEGQEKL-HQM-----WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQ  335

Query  196  NLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN  234
             L+     L  S+  L  ++  QV++ RR+VE     F+
Sbjct  336  QLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFS  374


>gi|42560524|sp|O60333|KIF1B_HUMAN  Kinesin-like protein KIF1B (Klp)
Length=1816

 Score = 30.0 bits (66),  Expect = 1.5
 Identities = 16/53 (30%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query  43   KEAVEHLQKSE-LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL  94
            +EA+E L++SE +  +LN  +++KL + E +R +       M   +RE+  +L
Sbjct  471  EEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTL  523


>gi|134798|sp|P11277|SPTB1_HUMAN  Spectrin beta chain, erythrocyte (Beta-I spectrin)
Length=2137

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 60/265 (22%), Positives = 104/265 (39%), Gaps = 45/265 (16%)

Query  39    SNNAKEAVE-----HLQKSELTQQLNALFQDKLGEAEQLR--RQLTPYAQRMERVLRENA  91
             S+  KE V+     H + +E  Q+ + L +D L     L+  ++LT +    +++L    
Sbjct  1242  SDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWIN--DKLLTSQD  1299

Query  92    DSLQASLRPHADELKAKID-----------QNVEELKGRLTPYADEFKVKIDQTVEELRR  140
              S   +   H   LK +             +N++    +L     +F   + Q +E L R
Sbjct  1300  VSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHR  1359

Query  141   SLAPYAQDTQEKLNHQLEGLTFQMK-KNAEELKARISASAEELR------------QRLA  187
                     T+EK  H     +  ++ +   +L   ISA  ++LR            + LA
Sbjct  1360  LWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNRMLA  1419

Query  188   PLAE-----DVRGNLRGNTEGLQKSLAELGGHLDQQVEE-FRRRVEPYGENFNKALVQQM  241
              L       +VR    G       S+ E GG  D  +E+ F   +EP G        +Q+
Sbjct  1420  KLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIEKRFLDLLEPLGRR-----KKQL  1474

Query  242   EQLRQKLGPHAGDVEGHLSFLEKDL  266
             E  R KL   + D+E    ++E+ L
Sbjct  1475  ESSRAKL-QISRDLEDETLWVEERL  1498


>gi|32699595|sp|Q96CN9|GCC1_HUMAN  GRIP and coiled-coil domain-containing protein 1 (Golgi coiled 
coil protein 1)
Length=775

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 17/124 (13%)

Query  144  PYAQDTQEKLNHQLEG----LTFQMKKNAEELKARISAS----AEELRQRLAPL---AED  192
            P+A    +K  HQL+     LT  +    +E K+R+ AS     ++++Q L      AE+
Sbjct  148  PFAGGEVDKRLHQLKTQLATLTSSLATVTQE-KSRMEASYLADKKKMKQDLEDASNKAEE  206

Query  193  VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA  252
             R  L G  +GLQ+ +AE    L  Q  +  +      ++ +  +++++++L Q+     
Sbjct  207  ERARLEGELKGLQEQIAETKARLITQQHDRAQE-----QSDHALMLRELQKLLQEERTQR  261

Query  253  GDVE  256
             D+E
Sbjct  262  QDLE  265


>gi|586120|sp|Q07283|TRHY_HUMAN  Trichohyalin
Length=1898

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 29/202 (14%)

Query  53    ELTQQLNALFQDK--LGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID  110
             E  QQL    +++  L E +QLRR      Q +ER  RE             ++L+ + +
Sbjct  1650  EEEQQLRRQERERKFLQEEQQLRR------QELERKFREE------------EQLRQETE  1691

Query  111   QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE  170
             Q     + R     +E +++ ++  ++LRR         +E+L    E    + +++  +
Sbjct  1692  QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQGREEQQLRSQESDRK  1751

Query  171   LKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY-  229
              +       E   Q+L P   D  G  R   E LQ  L E    L Q+ +   R  E + 
Sbjct  1752  FREEEQLRQEREEQQLRPQQRD--GKYRWEEEQLQ--LEEQEQRLRQERDRQYRAEEQFA  1807

Query  230   ----GENFNKALVQQMEQLRQK  247
                      + L Q+ EQ R++
Sbjct  1808  TQEKSRREEQELWQEEEQKRRQ  1829


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 18/202 (8%)

Query  43    KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHA  102
             +E  E LQ+ E  ++     + +  E EQL+       Q  E++LRE  +  +   R   
Sbjct  924   QEEEEELQREEREKRRRQEQERQYREEEQLQ-------QEEEQLLREEREKRRRQERERQ  976

Query  103   DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF  162
                  K+ Q  E+L G      +E + +  Q  E+  R      Q+ ++ L  + E    
Sbjct  977   YRKDKKLQQKEEQLLG------EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR  1030

Query  163   QMKKNAEELKARISASAEE-LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE  221
             Q  +     K  +    E+ LR+         R       E LQ+   +L G    +  E
Sbjct  1031  QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG----EERE  1086

Query  222   FRRRVEPYGENFNKALVQQMEQ  243
              RRR E   +   +  +QQ E+
Sbjct  1087  TRRRQELERQYRKEEELQQEEE  1108


>gi|126369|sp|P11047|LAMC1_HUMAN  Laminin gamma-1 chain precursor (Laminin B2 chain)
Length=1609

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 48/202 (23%), Positives = 84/202 (41%), Gaps = 19/202 (9%)

Query  62    FQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL-KAKIDQNVEELKGRL  120
             F+D+L EAE+    L   AQ ++ V +   D LQ      + ++ + +  +N  E  G L
Sbjct  1071  FEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNL  1130

Query  121   TPYADEFKVKIDQTVEELRRSL------APYAQDTQEKLNHQLEGLTFQMKKNAEELKAR  174
                A       ++ +E   R L      A     TQ +       +T  + + A +L  R
Sbjct  1131  AEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTL-LAEEARKLAER  1189

Query  175   ISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ--QVEEFRRRVEPYGEN  232
                 A+++  R+A  A D       +TE     L  L G      ++EE  R+ E   +N
Sbjct  1190  HKQEADDI-VRVAKTANDT------STEAYNLLLRTLAGENQTAFEIEELNRKYE-QAKN  1241

Query  233   FNKALVQQMEQLRQKLGPHAGD  254
              ++ L +Q  ++ ++    AGD
Sbjct  1242  ISQDLEKQAARVHEE-AKRAGD  1262


>gi|125953|sp|P20700|LMNB1_HUMAN  Lamin-B1
Length=586

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 35/189 (18%), Positives = 77/189 (40%), Gaps = 14/189 (7%)

Query  45   AVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE  104
            A E L K +L  +  +L +D       L  + + Y + +    R++   L         E
Sbjct  185  ADETLLKVDLENRCQSLTED-------LEFRKSMYEEEINETRRKHETRLVEVDSGRQIE  237

Query  105  LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM  164
             + K+ Q + E++ +       +K +++QT      +    ++     +N   E L  + 
Sbjct  238  YEYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREEL-MES  296

Query  165  KKNAEELKARISASAEELR------QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
            +   E L +++S   +E R      Q L  L    + N R      ++ +AE+   + QQ
Sbjct  297  RMRIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQ  356

Query  219  VEEFRRRVE  227
            + ++ + ++
Sbjct  357  LNDYEQLLD  365


>gi|122824|sp|P13196|HEM1_HUMAN  5-aminolevulinate synthase, nonspecific, mitochondrial precursor 
(5-aminolevulinic acid synthase) (Delta-aminolevulinate 
synthase) (Delta-ALA synthetase) (ALAS-H)
Length=640

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 1/80 (1%)

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
            AK  +  +EL  R   Y            EEL R +AP    T + +N+ LE L    K+
Sbjct  538  AKNTEVCDELMSRHNIYVQAINYPTVPRGEELLR-IAPTPHHTPQMMNYFLENLLVTWKQ  596

Query  167  NAEELKARISASAEELRQRL  186
               ELK   SA     R+ L
Sbjct  597  VGLELKPHSSAECNFCRRPL  616


>gi|71152997|sp|Q7Z3E2|CJ118_HUMAN  Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2)
Length=898

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 16/183 (8%)

Query  51   KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID  110
            K +L +    L Q K  EA+Q+R+      +  +      ++ L A LR    EL+ ++ 
Sbjct  410  KDKLKETTTKLTQAK-EEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQ  468

Query  111  QNVEELKGRLTPY--ADEFKVKIDQTVEELR--RSLAPYAQD----TQEKLNHQLEGLTF  162
            +  ++L+         ++ K    + ++ELR  R+     +D    T+++L+   E +  
Sbjct  469  EKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINR  528

Query  163  QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF  222
            Q K   + L  ++  +A++L+++L    +++  NL+   E    SL  L   L + +E  
Sbjct  529  Q-KAEIQNLLDKVK-TADQLQEQLQRGKQEIE-NLKEEVE----SLNSLINDLQKDIEGS  581

Query  223  RRR  225
            R+R
Sbjct  582  RKR  584


>gi|48474260|sp|O43790|KRHB6_HUMAN  Keratin, type II cuticular Hb6 (Hair keratin, type II Hb6) (ghHb6)
Length=486

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 33/176 (18%)

Query  72   LRRQLTPYAQRMERVLRENADSLQASLRPHAD------------ELKAKIDQNVEELKGR  119
            L  ++ P AQ +++  +E   SL +      D            E K +  QN E  +  
Sbjct  91   LNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSN  150

Query  120  LTPYADEFKVKIDQTVEELRRSLAPYAQDT---QEKLNHQLEGLTFQMKKNAEELKARIS  176
            L P  + +       +E LRR       D+     +LNH  E L    KK  EE+  R +
Sbjct  151  LEPLFEGY-------IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRAT  203

Query  177  ASAEELRQRLAPLAEDV------RGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRV  226
            A  E        L +DV      + +L  N E L + +  L    ++++   +  +
Sbjct  204  AENE-----FVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHI  254


>gi|47606192|sp|Q8WV44|TRI41_HUMAN  Tripartite motif protein 41
Length=630

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 26/141 (18%)

Query  120  LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA  179
            L     E+K K+ + VE LR+ L     +  +K+  + E    ++K    ++K+ ++A A
Sbjct  263  LEEVVQEYKAKLQEHVEPLRKHL-----EAVQKMKAKEERRVTELK---SQMKSELAAVA  314

Query  180  EELRQRLAPLAEDVRGNLR----------GNTEGLQKSLAELGGHLDQQVEEFRRRVEPY  229
             E  +    LAE+  G  R          G        LAE    L + + E + R +  
Sbjct  315  SEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQG  374

Query  230  G--------ENFNKALVQQME  242
            G        E FN+    Q++
Sbjct  375  GLRLLQDIKETFNRCEEVQLQ  395


>gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN  Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) 
(Myosin heavy chain 12) (Myoxin)
Length=1855

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 4/108 (3%)

Query  54    LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNV  113
             L  QL +  +    EAE LR ++    +   R  +  A +LQ  L P A  ++A +   +
Sbjct  1349  LESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQ--LPPEA-RIEASLQHEI  1405

Query  114   EELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT  161
               L        ++ + K D+TV +L++ L  +A+   E    Q+E ++
Sbjct  1406  TRLTNENLDLMEQLE-KQDKTVRKLKKQLKVFAKKIGELEVGQMENIS  1452


 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 40/206 (19%), Positives = 88/206 (42%), Gaps = 22/206 (10%)

Query  45    AVEHLQKSELTQQLNAL-FQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASL-RPHA  102
             +VE  +K  +  +   +  Q K+ E  +  + L      +E +     + L++ L R   
Sbjct  914   SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQL  973

Query  103   DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF  162
              E +AK+        GR+    +E   K+ + +E+ R S     ++  ++   + E    
Sbjct  974   SEEEAKV------ATGRVLSLQEEI-AKLRKDLEQTR-SEKKCIEEHADRYKQETE----  1021

Query  163   QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF  222
             Q+  N +E    +    E L  R+   A+++       TE ++K L E    L+  + + 
Sbjct  1022  QLVSNLKEENTLLKQEKEALNHRIVQQAKEM-------TETMEKKLVEETKQLELDLNDE  1074

Query  223   RRRVEPYGENFNKALVQQMEQLRQKL  248
             R R +     F++ L ++ + L++++
Sbjct  1075  RLRYQNLLNEFSR-LEERYDDLKEEM  1099


>gi|33112673|sp|Q9Y496|KIF3A_HUMAN  Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin 
motor 3A)
Length=702

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 4/92 (4%)

Query  50   QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV-LRENADSLQASLRPHADELKAK  108
            ++ +L ++ N   +++   AEQLRR+L    Q  ER+ + E   SLQ   +    +LK K
Sbjct  495  EQEKLLEESNMELEERRKRAEQLRRELEEKEQ--ERLDIEEKYTSLQEEAQGKTKKLK-K  551

Query  109  IDQNVEELKGRLTPYADEFKVKIDQTVEELRR  140
            +   +   K  +     E + +I+  +E +R+
Sbjct  552  VWTMLMAAKSEMADLQQEHQREIEGLLENIRQ  583


>gi|51701437|sp|Q8TF61|FBX41_HUMAN  F-box only protein 41
Length=875

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 14/90 (15%)

Query  110  DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE  169
            D   EE   RL   A E K+++D+ +E L       +++ ++K+  Q+  L  ++++ A 
Sbjct  195  DVAYEEGLARLKIRALE-KLEVDRRLERL-------SEEVEQKIAGQVGRLQAELERKAA  246

Query  170  ELK------ARISASAEELRQRLAPLAEDV  193
            EL+      AR+    EEL +R + L+  V
Sbjct  247  ELETARQESARLGREKEELEERASELSRQV  276


>gi|129886|sp|P16112|PGCA_HUMAN  Aggrecan core protein precursor (Cartilage-specific proteoglycan 
core protein) (CSPCP) (Chondroitin sulfate proteoglycan 
core protein 1) [Contains: Aggrecan core protein 2]
Length=2415

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 0/31 (0%)

Query  252  AGDVEGHLSFLEKDLRDKNWGLRLGDRDESG  282
            +GDV GHL F  +   D+  GL  GD D SG
Sbjct  872  SGDVSGHLDFSGQLSGDRASGLPSGDLDSSG  902


>gi|20532393|sp|O15230|LAMA5_HUMAN  Laminin alpha-5 chain precursor
Length=3695

 Score = 29.6 bits (65),  Expect = 2.0
 Identities = 19/69 (27%), Positives = 36/69 (52%), Gaps = 2/69 (2%)

Query  56    QQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLR--PHADELKAKIDQNV  113
             Q+LN+  Q++L EA Q +++L+     ++  L    D+L +  R     D+ K ++++  
Sbjct  2399  QELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLA  2458

Query  114   EELKGRLTP  122
               L G  TP
Sbjct  2459  ASLDGARTP  2467


>gi|37999758|sp|Q96PP9|GBP4_HUMAN  Guanylate binding protein 4
Length=640

 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 32/149 (21%), Positives = 64/149 (42%), Gaps = 21/149 (14%)

Query  30   VMWDY--FSQLSNNAKEAVEHLQKSELTQQLNALFQDKL---GE-AEQLRRQLTPYAQRM  83
            V WDY    +    A E +++  +S++  + + L  DK    GE A    R +   A++ 
Sbjct  457  VEWDYKLVPRKGVKANEVLQNFLQSQVVVEESILQSDKALTAGEKAIAAERAMKEAAEKE  516

Query  84   ERVLRENA-------DSLQASLRPHADELKAKIDQNVEEL--------KGRLTPYADEFK  128
            + +LRE         ++ + S + +  +LK K+++  E L        K +L    +  K
Sbjct  517  QELLREKQKEQQQMMEAQERSFQENIAQLKKKMERERENLLREHERLLKHKLKVQEEMLK  576

Query  129  VKIDQTVEELRRSLAPYAQDTQEKLNHQL  157
             +  +  E+L + +    +  +   N QL
Sbjct  577  EEFQKKSEQLNKEINQLKEKIESTKNEQL  605


 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 13/106 (12%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQ--LRRQLTPYAQRMER----VLRENADSLQA  96
            KEA E  Q+    +Q     Q ++ EA++   +  +    ++MER    +LRE+   L+ 
Sbjct  510  KEAAEKEQELLREKQKE---QQQMMEAQERSFQENIAQLKKKMERERENLLREHERLLKH  566

Query  97   SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL  142
             L+   + LK +  +  E+L   +    ++ K KI+ T  E  R L
Sbjct  567  KLKVQEEMLKEEFQKKSEQLNKEI----NQLKEKIESTKNEQLRLL  608


>gi|3183210|sp|Q15027|CENB1_HUMAN  Centaurin-beta 1 (Cnt-b1)
Length=740

 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 42/178 (23%), Positives = 70/178 (39%), Gaps = 14/178 (7%)

Query  54   LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNV  113
            L QQ+  L ++ L    + RR     A+ +E  L  NA+ +       A+E  A +    
Sbjct  105  LQQQIQTLVKEGLRGFREARRDFWRGAESLEAALTHNAE-VPRRRAQEAEEAGAALRTAR  163

Query  114  EELKGRLTPYA-------DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
               +GR   YA       D+ K  I + V  L  + A + Q   E+L+ +L     ++  
Sbjct  164  AGYRGRALDYALQINVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELS-RLSQYRKELGA  222

Query  167  NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR  224
               +L    +    ++ QR   L +   G      E  + SL E  G L  +   F+R
Sbjct  223  QLHQLVLNSAREKRDMEQRHVLLKQKELGG-----EEPEPSLREGPGGLVMEGHLFKR  275


>gi|2498733|sp|Q14444|GP137_HUMAN  GPI-anchored protein p137 (p137GPI) (Membrane component chromosome 
11 surface marker 1)
Length=649

 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 51/208 (24%), Positives = 83/208 (39%), Gaps = 45/208 (21%)

Query  56   QQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEE  115
            +Q+  +   KL   E+ + +L  Y +RM +  R N D L A  +        ++  N+E 
Sbjct  2    KQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSK------YQEVTNNLEF  55

Query  116  LKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE--KLNHQLEGLTFQMKKNAEELKA  173
             K                   EL+RS    +QD Q+  K   + E L   M++ AE+ + 
Sbjct  56   AK-------------------ELQRSFMALSQDIQKTIKKTARREQL---MREEAEQKRL  93

Query  174  RISASAEELRQRLAPLAED-VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP----  228
            +   +  EL+  L  L +D VR +L+    G+     E    LD    EF + V+P    
Sbjct  94   K---TVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLD----EFYKLVDPERDM  146

Query  229  ---YGENFNKALVQQMEQLRQKLGPHAG  253
                 E +  A +   + L  K  P  G
Sbjct  147  SLRLNEQYEHASIHLWDLLEGKEKPVCG  174


>gi|46397468|sp|Q14533|KRHB1_HUMAN  Keratin, type II cuticular Hb1 (Hair keratin, type II Hb1) (ghHKb1) 
(ghHb1) (MLN 137)
Length=505

 Score = 29.3 bits (64),  Expect = 2.6
 Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 33/154 (21%)

Query  72   LRRQLTPYAQRMERVLRENADSLQASLRPHAD------------ELKAKIDQNVEELKGR  119
            L  ++ P AQ +++  +E   SL +      D            E K +  QN E  +  
Sbjct  91   LNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSN  150

Query  120  LTPYADEFKVKIDQTVEELRRSLAPYAQDT---QEKLNHQLEGLTFQMKKNAEELKARIS  176
            L P  + +       +E LRR       D+     +LNH  E L    KK  EE+  R +
Sbjct  151  LEPLFEGY-------IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRAT  203

Query  177  ASAEELRQRLAPLAEDV------RGNLRGNTEGL  204
            A  E        L +DV      + +L  N E L
Sbjct  204  AENE-----FVALKKDVDCAYLRKSDLEANVEAL  232


>gi|6136547|sp|O60299|Y0552_HUMAN  Hypothetical protein KIAA0552
Length=673

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM--  164
            A + +++E+ +  +    +E +   ++ + ELR+  +   Q    +     +GL  Q+  
Sbjct  336  AALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLR  395

Query  165  ----KKNAEELKARISASAEELRQRLA  187
                KK  +E  AR+    EEL  ++A
Sbjct  396  LQQDKKQLQEEAARLMRQREELEDKVA  422


>gi|34223086|sp|Q9UKI8|TLK1_HUMAN  Serine/threonine-protein kinase tousled-like 1 (Tousled-like 
kinase 1) (PKU-beta)
Length=766

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 9/75 (12%)

Query  202  EGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF  261
            EG    L      L +Q++E ++ +E Y E  NK +    + L +K        +  LS 
Sbjct  236  EGRIDDLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEK------STQEKLSS  289

Query  262  LEKDLRDKNWGLRLG  276
             EK ++D+   LRLG
Sbjct  290  REKSMQDR---LRLG  301


>gi|41702296|sp|Q8NI27|THOC2_HUMAN  THO complex subunit 2 (Tho2)
Length=1478

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 36/170 (21%), Positives = 72/170 (42%), Gaps = 28/170 (16%)

Query  63    QDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTP  122
             ++K  E E+ +++ TP      RVL ++        RP+ DE          E K R TP
Sbjct  1156  KEKGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDE-------KARETKER-TP  1207

Query  123   YADEFKVKI---DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA  179
              +D+ K K    ++  +E  ++  P A+    +            ++  E+  +R    A
Sbjct  1208  KSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQ------------EREREKEPSRERDIA  1255

Query  180   EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY  229
             +E++ +     E+V+G  +    G  KS        + + E+ RR+++ +
Sbjct  1256  KEMKSK-----ENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTH  1300


>gi|2497523|sp|Q12756|KIF1A_HUMAN  Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles)
Length=1690

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query  42   AKEAVEHLQKSE-LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL  94
            ++EA+E L+++E +  +LN  +++KL   E +R +       M   +RE+  +L
Sbjct  430  SEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTL  483


>gi|3913961|sp|O43896|KIF1C_HUMAN  Kinesin-like protein KIF1C
Length=1103

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 16/53 (30%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query  43   KEAVEHLQKSE-LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSL  94
            +EA+E LQ++E +  +LN  +++KL + E LR +       M   +RE+  ++
Sbjct  438  EEAMERLQETEKIIAELNETWEEKLRKTEALRMEREALLAEMGVAVREDGGTV  490


>gi|25014073|sp|O43615|TIM44_HUMAN  Import inner membrane translocase subunit TIM44, mitochondrial 
precursor
Length=452

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 39/193 (20%), Positives = 78/193 (40%), Gaps = 26/193 (13%)

Query  26   QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMER  85
            + + V+     +L+   KE++  + KS+L +++    ++    A+Q    ++   +++ R
Sbjct  113  RTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGR  172

Query  86   VLRENADSLQASLRPHADELKAKIDQNV----------EELKGRLTPYADEFK-VKIDQT  134
                 A      L    + +K +ID +V          + L+ R     D+FK  K+ + 
Sbjct  173  TAAFRA------LSQGVESVKKEIDDSVLGQTGPYRRPQRLRKRTEFAGDKFKEEKVFEP  226

Query  135  VEE-----LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
             EE     L +    Y Q    K N+ +    F+MK   +E       ++  L  ++   
Sbjct  227  NEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKVT--  284

Query  190  AEDVRGNLRGNTE  202
              D+ G L   TE
Sbjct  285  --DLLGGLFSKTE  295


>gi|84027768|sp|O75150|BRE1B_HUMAN  Ubiquitin ligase protein BRE1B (BRE1-B) (RING finger protein 
40) (95 kDa retinoblastoma-associated protein) (RBP95)
Length=1001

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 33/162 (20%), Positives = 78/162 (48%), Gaps = 19/162 (11%)

Query  147  QDTQEKLNHQLEGLTFQMKKNAEELKA------RISASAEELRQRLAPLAEDVRGNLRGN  200
            ++T+ K +  L+GL  ++KK  E  K          ++ +E R ++  +A + +   +  
Sbjct  642  EETKRKESELLKGLRAELKKAQESQKEMKLLLDMYKSAPKEQRDKVQLMAAERKA--KAE  699

Query  201  TEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLS  260
             + L+  + EL    ++   E ++  +       +   +Q+E L++KLG    + E  LS
Sbjct  700  VDELRSRIRELE---ERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEEEALLS  756

Query  261  FLE------KDLRDKNWGL--RLGDRDESGEEGQSRGMQALQ  294
             ++      +D++++N  L  +L ++D++  +  S  ++A Q
Sbjct  757  EMDVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERIKANQ  798


>gi|1171955|sp|P42338|PK3CB_HUMAN  Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 
beta isoform (PI3-kinase p110 subunit beta) (PtdIns-3-kinase 
p110) (PI3K) (PI3Kbeta)
Length=1070

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 8/72 (11%)

Query  206  KSLAELGGHLDQQVEEFRRRVEPYGENFNKALV--QQMEQLRQKLGPHAGDVEGHLSFLE  263
            K L E     D +V EFRR++  + E    +LV    M+ L+Q   P       H   + 
Sbjct  132  KGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPE------HEPSIP  185

Query  264  KDLRDKNWGLRL  275
            ++L DK +G +L
Sbjct  186  ENLEDKLYGGKL  197


>gi|47605777|sp|O95140|MFN2_HUMAN  Transmembrane GTPase MFN2 (Mitofusin-2)
Length=757

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 18/158 (11%)

Query  66   LGEAEQLRR-QLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYA  124
            L E  Q+R  +   + +R E  + ++A  ++     H    K +I + V  +   L   A
Sbjct  327  LAEGFQVRMFEFQNFERRFEECISQSA--VKTKFEQHTVRAK-QIAEAVRLIMDSLHMAA  383

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT----FQMKKNAEELKARIS-ASA  179
             E +V  ++  EE         QD  + ++ QLE L      ++K+  EE++ ++S A A
Sbjct  384  REQQVYCEEMREE--------RQDRLKFIDKQLELLAQDYKLRIKQITEEVERQVSTAMA  435

Query  180  EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ  217
            EE+R RL+ L +D + +   +   L+    EL  H+++
Sbjct  436  EEIR-RLSVLVDDYQMDFHPSPVVLKVYKNELHRHIEE  472


>gi|25452905|sp|Q9H501|CT006_HUMAN  Hypothetical protein C20orf6
Length=851

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query  34   YFSQLSNNAKEAVEHLQKSE--LTQQLNALFQDKLGEAEQLR--RQLTPYAQRMERVLRE  89
            Y +  S + +E  E LQ  +    ++     + +  + EQ+   RQL    Q  E+  +E
Sbjct  539  YLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKE  598

Query  90   NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDT  149
            N   ++    P   E   ++ +N  E K +LTP+    + K ++  + L+R     A++ 
Sbjct  599  NDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEK--KRLKRKQKALAEEA  656

Query  150  QEK  152
             E+
Sbjct  657  SEE  659


>gi|134517|sp|P12755|SKI_HUMAN  Ski oncogene (C-ski)
Length=728

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 11/114 (9%)

Query  42   AKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPH  101
            A EA  +L+K    ++L A  + K+ EA + R        R++R L +   +        
Sbjct  605  ATEAKRNLRKE--IERLRAENEKKMKEANESRL-------RLKRELEQARQARVCDKGCE  655

Query  102  ADELKAKIDQNVEELKGRLT-PYADEFKVKIDQTVE-ELRRSLAPYAQDTQEKL  153
            A  L+AK    +E+L+ +L    AD  +++ D   E E R  L    ++ QE+L
Sbjct  656  AGRLRAKYSAQIEDLQVKLQHAEADREQLRADLLREREAREHLEKVVKELQEQL  709


>gi|56417894|sp|Q8NE71|ABCF1_HUMAN  ATP-binding cassette sub-family F member 1 (ATP-binding cassette 
50) (TNF-alpha-stimulated ABC protein)
Length=845

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query  84   ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA  143
            + V+ +   ++QA LR  AD  + K+ +    L+G+L    D    ++++  EELR   A
Sbjct  367  QEVVADETPAVQAVLR--ADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR---A  421

Query  144  PYAQDTQEKLNHQLEGLTF  162
              A   + K    L GL F
Sbjct  422  TGAAAAEAKARRILAGLGF  440


>gi|52783461|sp|Q8NEE8|TTC16_HUMAN  Tetratricopeptide repeat protein 16 (TPR repeat protein 16)
Length=873

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 20/69 (28%), Positives = 27/69 (39%), Gaps = 6/69 (8%)

Query  33   DYFSQLSNNAKEAVEHLQKSELTQQ------LNALFQDKLGEAEQLRRQLTPYAQRMERV  86
            D F QL N A    ++ Q   L+ Q         L Q+K+G  EQ R+Q           
Sbjct  373  DCFFQLGNLAFAEADYQQALALSPQDEGANTRTGLLQEKMGFCEQRRKQFQKAENHFSTA  432

Query  87   LRENADSLQ  95
            +R N    Q
Sbjct  433  IRHNPQKAQ  441


>gi|88909227|sp|Q6WCQ1|MRIP_HUMAN  Myosin phosphatase Rho-interacting protein (Rho-interacting protein 
3) (M-RIP) (RIP3) (p116Rip)
Length=1024

 Score = 28.9 bits (63),  Expect = 3.4
 Identities = 36/150 (24%), Positives = 62/150 (41%), Gaps = 13/150 (8%)

Query  44   EAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD  103
            E  +  Q S +   + AL +  L E + ++R+L   +++  +   ENA   QA L     
Sbjct  787  EKSQRSQISSVNSDVEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQA-LEAERQ  845

Query  104  ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL-------APYAQDTQEKLNHQ  156
             L+    +N E     L  +  E   ++   +  LR  L       A  +   Q K  ++
Sbjct  846  ALRQCQRENQE-----LNAHNQELNNRLAAEITRLRTLLTGDGGGEATGSPLAQGKDAYE  900

Query  157  LEGLTFQMKKNAEELKARISASAEELRQRL  186
            LE L    +   + LK  IS+  +EL+  L
Sbjct  901  LEVLLRVKESEIQYLKQEISSLKDELQTAL  930


>gi|125962|sp|P02545|LMNA_HUMAN  Lamin-A/C (70 kDa lamin)
Length=664

 Score = 28.5 bits (62),  Expect = 4.4
 Identities = 38/179 (21%), Positives = 71/179 (39%), Gaps = 16/179 (8%)

Query  41   NAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRM--ERVLRENADSLQASL  98
            N+KEA      SE  + L     D  G+  +L   L    +++  E + R +A++   ++
Sbjct  142  NSKEAALSTALSE-KRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTM  200

Query  99   RPHADELKAKIDQNVEELKGRLTPYA--------DEFKVKIDQTVEELRRSLAPYAQDTQ  150
            +   D  K    + + E K R              EF+ ++   ++ELR       +  +
Sbjct  201  KEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYK  260

Query  151  EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLA  209
            ++L           +++AE     + A+ EEL+Q    +      +L      LQK LA
Sbjct  261  KELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRI-----DSLSAQLSQLQKQLA  314


>gi|20138952|sp|Q15025|NAF1_HUMAN  Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) 
(HIV-1 Nef-interacting protein) (Virion-associated nuclear 
shuttling protein) (VAN) (hVAN) (Nip40-1)
Length=636

 Score = 28.5 bits (62),  Expect = 4.4
 Identities = 41/220 (18%), Positives = 86/220 (39%), Gaps = 30/220 (13%)

Query  47   EHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELK  106
            E L+K    + L A     L + +Q   +L      ++++L  N +   AS RP + +++
Sbjct  213  EQLRKEN--EALKAKLDKGLEQRDQAAERLREENLELKKLLMSNGNKEGASGRPGSPKME  270

Query  107  AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK  166
                + V   +        +  V   +  E +    A       E+   +L  +  Q  +
Sbjct  271  GTGKKAVAGQQ--------QASVTAGKVPEVVALGAAEKKVKMLEQQRSELLEVNKQWDQ  322

Query  167  NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRV  226
            +   +K +      ELRQ+LA                LQK + +L    +Q+  +F R++
Sbjct  323  HFRSMKQQYEQKITELRQKLA---------------DLQKQVTDLEAEREQKQRDFDRKL  367

Query  227  EPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL  266
                    K+ ++  E  +++L   A ++   + +L+  L
Sbjct  368  -----LLAKSKIEMEETDKEQLTAEAKELRQKVKYLQDQL  402


>gi|13124704|sp|Q14457|BCN1_HUMAN  Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein 
GT197)
Length=450

 Score = 28.5 bits (62),  Expect = 4.4
 Identities = 28/124 (22%), Positives = 59/124 (47%), Gaps = 15/124 (12%)

Query  36   SQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQ  95
            +QL+    E   + +  E+ +Q+N        ++EQL+ +L   A   ER+++E  D ++
Sbjct  150  TQLNVTENECQNYKRCLEILEQMNE------DDSEQLQMELKELALEEERLIQELED-VE  202

Query  96   ASLRPHADELKAKIDQNVEELKGRLTPYADEF------KVKIDQTVEELRRSLAPYAQDT  149
             + +  A+ L+ K+    E L      Y  E+      ++++D  ++ +   +  YAQ  
Sbjct  203  KNRKIVAENLE-KVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR-YAQTQ  260

Query  150  QEKL  153
             +KL
Sbjct  261  LDKL  264


>gi|33302627|sp|Q15643|TRIPB_HUMAN  Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated 
microtubule-binding protein 210) (GMAP-210) (Trip230) 
(Clonal evolution related gene on chromosome 14)
Length=1979

 Score = 28.5 bits (62),  Expect = 4.4
 Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 38/257 (14%)

Query  49    LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV------LRENADSLQASL---R  99
             L  S+   +L   +   +   EQ   +L  + Q + +V      L    D L   L    
Sbjct  1254  LVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIIS  1313

Query  100   PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG  159
             P          Q+ E L+   +    E    + Q +EELR+SL       QEK     + 
Sbjct  1314  PQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSL-------QEK-----DA  1361

Query  160   LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQV  219
                 +++N   L   I+A++E  R+       +++  L+   + LQK L E     D  +
Sbjct  1362  TIRTLQENNHRLSDSIAATSELERKEHEQTDSEIK-QLKEKQDVLQKLLKE----KDLLI  1416

Query  220   EEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKNWGLRLGDRD  279
             +    ++    ENF    V + E LRQ +     +++  +  LE D+     G   G+ +
Sbjct  1417  KAKSDQLLSSNENFTNK-VNENELLRQAV----TNLKERILILEMDI-----GKLKGENE  1466

Query  280   ESGE--EGQSRGMQALQ  294
             +  E   G+    QALQ
Sbjct  1467  KIVETYRGKETEYQALQ  1483


 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 8/97 (8%)

Query  23    SADQVATVMWDYFSQLSNNAKEAVEHLQKS--------ELTQQLNALFQDKLGEAEQLRR  74
             SA+ +     +  S+ S   ++ +E L+KS           Q+ N    D +    +L R
Sbjct  1326  SAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELER  1385

Query  75    QLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQ  111
             +         + L+E  D LQ  L+     +KAK DQ
Sbjct  1386  KEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQ  1422


>gi|30173225|sp|O95347|SMC2_HUMAN  Structural maintenance of chromosome 2-like 1 protein (Chromosome-associated 
protein E) (hCAP-E) (XCAP-E homolog)
Length=1197

 Score = 28.5 bits (62),  Expect = 4.4
 Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 9/113 (7%)

Query  68   EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL---KAKIDQNVEEL-KGRLTPY  123
            E E+L+R+ T Y Q++E V  E   S ++ +   A E+   K  +++  EE+ K +    
Sbjct  825  ELEELKREHTSYKQQLEAV-NEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVIT  883

Query  124  ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS  176
            A +  +K++    +  RS         ++L+H +     + K+ AE+  A++S
Sbjct  884  AQDTVIKLNMQKWQNTRSKTMILSLKIKELDHHIS----KHKREAEDGAAKVS  932


>gi|62511890|sp|Q6UWE0|LRSM1_HUMAN  Ubiquitin ligase protein LRSAM1 (Leucine-rich repeat and sterile 
alpha motif containing 1) (Tsg101-associated ligase) (hTAL)
Length=723

 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 25/161 (15%)

Query  68   EAEQLRRQLTPYAQRMERVLRENAD---SLQASLRPHADELKAKIDQNVEELKGRLTPYA  124
            E  + + + + Y +R E+ + E  +    L+   R H   L+    Q  E L        
Sbjct  245  EELEWQNRFSDYEKRKEQKMLEKLEFERRLELGQREHTQLLQQSSSQKDEIL--------  296

Query  125  DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ  184
                    QTV+E +  L     + Q  LN + + L  Q+K+  + + +RI    ++  Q
Sbjct  297  --------QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSRIQKLLQD-NQ  347

Query  185  RLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR  225
            R    +E ++     + E  +  + +L     ++ E  RRR
Sbjct  348  RQKKSSEILK-----SLENERIRMEQLMSITQEETESLRRR  383


>gi|48474320|sp|P78385|KRHB3_HUMAN  Keratin, type II cuticular Hb3 (Hair keratin, type II Hb3)
Length=493

 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 39/154 (25%), Positives = 57/154 (37%), Gaps = 33/154 (21%)

Query  72   LRRQLTPYAQRMERVLRENADSLQASLRPHAD------------ELKAKIDQNVEELKGR  119
            L  ++ P AQ +++  +E   SL +      D            E K +  QN E  +  
Sbjct  96   LNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNCECCQSN  155

Query  120  LTPYADEFKVKIDQTVEELRRSLAPYAQDT---QEKLNHQLEGLTFQMKKNAEELKARIS  176
            L P    +       +E LRR       D+     +LNH  E L    KK  EE+  R +
Sbjct  156  LEPLFAGY-------IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRAT  208

Query  177  ASAEELRQRLAPLAEDV------RGNLRGNTEGL  204
            A  E        L +DV      + +L  N E L
Sbjct  209  AENE-----FVALKKDVDCAYLRKSDLEANVEAL  237


>gi|71658803|sp|Q6TFL3|CI093_HUMAN  Protein C9orf93
Length=1326

 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 32/115 (27%), Positives = 47/115 (40%), Gaps = 19/115 (16%)

Query  70   EQLRRQLTPYAQRMERVLRE-----NADSLQASLRPHA---DELKAKIDQNVEELKGRLT  121
            E+LRR LT Y  ++E    E       DS +  +  H     EL+ K+    +EL    T
Sbjct  456  ERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHT  515

Query  122  PYADE------FKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE  170
              AD        KV++   +    +  A  AQ   E     L+ L+    K+AEE
Sbjct  516  KCADREALISTLKVELQNVLHCWEKEKAQAAQSESE-----LQKLSQAFHKDAEE  565


>gi|56405102|sp|Q9UJ41|RABX5_HUMAN  Rab5 GDP/GTP exchange factor (Rabex-5)
Length=708

 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 1/80 (1%)

Query  39   SNNAKEAVEHLQKS-ELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQAS  97
            S +A   V+ + K+ +L  QLN   +  + EA++L + L  +   + R +++  +     
Sbjct  617  SPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLE  676

Query  98   LRPHADELKAKIDQNVEELK  117
            ++P    L A   +NVE  K
Sbjct  677  IKPPNQPLAAIDSENVENDK  696


>gi|34978376|sp|Q9P2E2|KIF17_HUMAN  Kinesin-like protein KIF17 (KIF3-related motor protein)
Length=1029

 Score = 28.1 bits (61),  Expect = 5.7
 Identities = 32/124 (25%), Positives = 50/124 (40%), Gaps = 22/124 (17%)

Query  79   YAQRMERVL---RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV  135
            YA R + +    R N D   A LR + +E+K        +LK  LT       +      
Sbjct  328  YANRAKNIRNKPRINEDPKDALLREYQEEIK--------KLKAILTQQMSPSSLSA----  375

Query  136  EELRRSLAPYAQDTQEKL------NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL  189
              L R + P     +EKL       H +E     +++  EE  AR+ A  +  ++  A L
Sbjct  376  -LLSRQVPPDPVQVEEKLLPQPVIQHDMEAEKQLIREEYEERLARLKADYKAEQESRARL  434

Query  190  AEDV  193
             ED+
Sbjct  435  EEDI  438


>gi|13124096|sp|Q9ULW0|TPX2_HUMAN  Targeting protein for Xklp2 (Restricted expression proliferation 
associated protein 100) (p100) (Differentially expressed 
in cancerous and noncancerous lung cells 2) (DIL-2) (Protein 
FLS353) (Hepatocellular carcinoma-associated antigen 519)
Length=747

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 41/197 (20%), Positives = 79/197 (40%), Gaps = 30/197 (15%)

Query  64   DKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPY  123
            D   +  QL+++     ++++ + +      +A   PH D +      N+ E K +    
Sbjct  541  DSRDKERQLQKE-----KKIKELQKGEVPKFKALPLPHFDTI------NLPEKKVKNVTQ  589

Query  124  ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA----------EELKA  173
             + F ++ D+      ++   +    +E+L  Q E   F+ + N           +E K+
Sbjct  590  IEPFCLETDRRGALKAQT---WKHQLEEELRQQKEAACFKARPNTVISQEPFVPKKEKKS  646

Query  174  RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF  233
                 +  L Q    LA + R   R   + L+K +AE+     QQ+EE R + E   E  
Sbjct  647  VAEGLSGSLVQEPFQLATEKRAKER---QELEKRMAEVEAQKAQQLEEARLQEE---EQK  700

Query  234  NKALVQQMEQLRQKLGP  250
             + L +   +L  K  P
Sbjct  701  KEELARLRRELVHKANP  717


>gi|25009488|sp|Q9C030|TRIM6_HUMAN  Tripartite motif protein 6 (RING finger protein 89)
Length=488

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 26/138 (18%), Positives = 60/138 (43%), Gaps = 12/138 (8%)

Query  54   LTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNV  113
            L +++   +Q+K  E+ +  +     A+++   +RE   S +  + P     + +I    
Sbjct  132  LVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPE----RCRIQTEF  187

Query  114  EELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA  173
             +L+  L         K++Q  ++  R +    ++ +  L HQ + L    ++   +L+ 
Sbjct  188  NQLRNILDRVEQRELKKLEQEEKKGLRII----EEAENDLVHQTQSL----RELISDLER  239

Query  174  RISASAEELRQRLAPLAE  191
            R   S  EL Q ++ + E
Sbjct  240  RCQGSTMELLQDVSDVTE  257


>gi|14424221|sp|O75154|RFIP3_HUMAN  Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing 
Rab-interacting protein) (Eferin)
Length=756

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 7/102 (6%)

Query  39   SNNAKEAVEHLQKSELTQQLNALFQDKLG---EAEQLRRQLTPYAQRMERVLRENA--DS  93
            S   +E     ++SEL Q++  L QD      + E+L  Q+   + +  + L   A  +S
Sbjct  648  SMGLQEYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSES  707

Query  94   LQASLRPHA-DELKAKIDQNVEELKGRLTPYADEFKVKIDQT  134
            L A +   + DEL   I Q  EE+  RL  Y D   V I +T
Sbjct  708  LAAEISSVSRDELMEAI-QKQEEINFRLQDYIDRIIVAIMET  748


>gi|56749614|sp|Q6NZI2|PTRF_HUMAN  Polymerase I and transcript release factor (PTRF protein)
Length=390

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 22/96 (22%), Positives = 49/96 (51%), Gaps = 11/96 (11%)

Query  81   QRMERV---LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEE  137
            ++ME+     REN +  +   + + ++ +  +++ + +L  RL P   E + K+  + ++
Sbjct  239  EKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVP--AERREKLKTSRDK  296

Query  138  LRRSLAP----YAQDTQEKLNHQLEGLTFQMKKNAE  169
            LR+S  P    YA+   +   +++   TF +KK  E
Sbjct  297  LRKSFTPDHVVYAR--SKTAVYKVPPFTFHVKKIRE  330


>gi|21264472|sp|P37198|NUP62_HUMAN  Nuclear pore glycoprotein p62 (62 kDa nucleoporin)
Length=522

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 7/122 (5%)

Query  57   QLNALFQDKLGEAEQLRRQLTPYAQRM---ERVLRENADSLQASLRPHADELKA---KID  110
            QL +L      E E   R     A ++   +R L EN + +  SL    +++K    ++D
Sbjct  332  QLESLINKWSLELEDQERHFLQQATQVNAWDRTLIENGEKI-TSLHREVEKVKLDQKRLD  390

Query  111  QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE  170
            Q ++ +  +     D      +   E+       +A + +EK     E +  Q+K+ A++
Sbjct  391  QELDFILSQQKELEDLLSPLEELVKEQSGTIYLQHADEEREKTYKLAENIDAQLKRMAQD  450

Query  171  LK  172
            LK
Sbjct  451  LK  452


>gi|12644130|sp|P15924|DESP_HUMAN  Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Length=2871

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 17/87 (19%), Positives = 42/87 (48%), Gaps = 4/87 (4%)

Query  50    QKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERV---LRENADSLQASLRPHADELK  106
             +K ++   LN  ++ +    E+  R++    ++ ER    LR   + LQA ++   +  +
Sbjct  1856  EKQQIQNDLNQ-WKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCR  1914

Query  107   AKIDQNVEELKGRLTPYADEFKVKIDQ  133
              K++ +  E + +L      ++ +ID+
Sbjct  1915  RKLEDSTRETQSQLETERSRYQREIDK  1941


>gi|41688815|sp|Q9NQZ6|HC127_HUMAN  Hepatocellular carcinoma-associated antigen 127
Length=224

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 37/158 (23%), Positives = 68/158 (43%), Gaps = 17/158 (10%)

Query  49   LQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD--ELK  106
            LQ  ++  +L A F+      E   R L  Y Q M+ +L+E    ++     HAD   ++
Sbjct  22   LQMEKIKARLKAEFE----ALESEERHLKEYKQEMDLLLQEKMAHVEELRLIHADINVME  77

Query  107  AKIDQNVEELKGRLTP---YADEFKVKIDQTVEELRRSLA----PYAQDTQEKLN---HQ  156
              I Q+  +L   L       DE+K  + + V+ LR +L     P   + +EKL+    +
Sbjct  78   NTIKQSENDLNKLLESTRRLHDEYK-PLKEHVDALRMTLGLQRLPDLCEEEEKLSLDYFE  136

Query  157  LEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVR  194
             +   +Q +     +   ++A+A   +Q      +D R
Sbjct  137  KQKAEWQTEPQEPPIPESLAAAAAAAQQLQVARKQDTR  174


>gi|62899891|sp|Q9HC77|CENPJ_HUMAN  Centromere protein J (Centrosomal P4.1-associated protein) (LAG-3-associated 
protein) (LYST-interacting protein 1)
Length=1338

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 15/101 (14%)

Query  108   KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN  167
             +++  +E+ K      A + +++ +  +E+LR+ +A + Q   ++L    E    +M+K 
Sbjct  912   ELETEIEKFKAENASLA-KLRIERESALEKLRKEIADFEQQKAKELARIEEFKKEEMRKL  970

Query  168   AEELK--------ARISASAEE------LRQRLAPLAEDVR  194
              +E K        AR     +E      L+Q++A L ED++
Sbjct  971   QKERKVFEKYTTAARTFPDKKEREEIQTLKQQIADLREDLK  1011


>gi|47116932|sp|Q9NQ29|LUC7L_HUMAN  Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR 
protein LUC7B1)
Length=371

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 27/145 (18%)

Query  163  QMKKNAEELKARISASAE---ELRQRLAP-LAEDVRGNLRGNTEGLQKSLAELGGHLDQQ  218
            ++ +  EE+ A +SA AE   EL + +   LA+  +    GN +  QK L E+     ++
Sbjct  107  RLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV-----EK  161

Query  219  VEEFRRRVEPYGENFNKALVQQMEQLR---------------QKLGPHAGDVEGHLSFLE  263
            V   ++  E    N   A   Q ++LR               ++L  H G  + HL F++
Sbjct  162  VRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGG-KLHLGFIQ  220

Query  264  KDLRDKNWGLRLGDRDESGEEGQSR  288
              +R+K   LR    ++  +  Q R
Sbjct  221  --IREKLDQLRKTVAEKQEKRNQDR  243


>gi|29427676|sp|Q16891|IMMT_HUMAN  Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing 
gene 4 protein)
Length=758

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 23/154 (14%)

Query  44   EAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD  103
            +A+EH +     +Q   + + +     ++R QL        R    + D L+  LR    
Sbjct  451  KALEHHRSEIQAEQDRKIEEVRDAMENEMRTQL-------RRQAAAHTDHLRDVLRVQEQ  503

Query  104  ELKAKIDQNVEE--------LKGRLTPYADEFKVKIDQTVEELR---RSLAPYAQDTQE-  151
            ELK++ +QN+ E         +       D F + I+     LR   +++  +A   +E 
Sbjct  504  ELKSEFEQNLSEKLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEA  563

Query  152  KLNHQL----EGLTFQMKKNAEELKARISASAEE  181
            +  HQL    E L + MK ++ E       SA E
Sbjct  564  RKAHQLWLSVEALKYSMKTSSAETPTIPLGSAVE  597


>gi|13432173|sp|P02533|K1C14_HUMAN  Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) 
(K14)
Length=472

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 20/90 (22%), Positives = 40/90 (44%), Gaps = 7/90 (7%)

Query  68   EAEQLRRQLTPYAQRMER------VLRENADSLQASLRPHADELKAKIDQNVEELKGRLT  121
            + E+L R++   ++ ++        LR    +L+  L+     +KA ++ ++EE KGR  
Sbjct  309  KTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLS-MKASLENSLEETKGRYC  367

Query  122  PYADEFKVKIDQTVEELRRSLAPYAQDTQE  151
                + +  I    E+L +      Q  QE
Sbjct  368  MQLAQIQEMIGSVEEQLAQLRCEMEQQNQE  397


>gi|57013034|sp|O95425|SVIL_HUMAN  Supervillin (Archvillin) (p205/p250)
Length=2214

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 30/109 (27%), Positives = 45/109 (41%), Gaps = 2/109 (1%)

Query  65    KLGEAEQLRRQLTPYAQRM-ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPY  123
             KL   E   R+L      M E VL     S++  ++P  DE  AK  ++V+    R    
Sbjct  1266  KLDRLETFLRRLNNKVGGMHETVLTVTGKSVKEVMKPDDDETFAKFYRSVDYNMPRSPVE  1325

Query  124   ADE-FKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEEL  171
              DE F V  D    +L  S+A + +  + K   Q      +M    E+L
Sbjct  1326  MDEDFDVIFDPYAPKLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDL  1374


>gi|57015308|sp|Q14204|DYHC_HUMAN  Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy 
chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1)
Length=4646

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 7/65 (10%)

Query  69   AEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK  128
            A+Q+ RQLT Y +R+E VL +  ++       H +  K K D +   +K       D++ 
Sbjct  651  AKQIDRQLTAYMKRVEDVLGKGWEN-------HVEGQKLKQDGDSFRMKLNTQEIFDDWA  703

Query  129  VKIDQ  133
             K+ Q
Sbjct  704  RKVQQ  708


>gi|62510844|sp|O95202|LETM1_HUMAN  Leucine zipper-EF-hand containing transmembrane protein 1, mitochondrial 
precursor
Length=739

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 37/211 (17%), Positives = 81/211 (38%), Gaps = 15/211 (7%)

Query  64   DKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPY  123
            D L  A+QL+  L    Q +  ++ + A    A +     + KAK++  ++E       +
Sbjct  425  DTLSPADQLKSTL----QTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEH  480

Query  124  ADEFKVKIDQTVEEL---RRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE  180
             ++   K  +  ++    R   AP    T+ +   ++     Q +   +          E
Sbjct  481  REKELQKRSEVAKDFEPERVVAAPQRPGTEPQ--PEMPDTVLQSETLKDTAPVLEGLKEE  538

Query  181  ELRQRLAPLAEDVRGNLRGNTEGLQKSLAELG------GHLDQQVEEFRRRVEPYGENFN  234
            E+ +    +  D    L+   + L K   EL           + ++E ++ +   GE   
Sbjct  539  EITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKY  598

Query  235  KALVQQMEQLRQKLGPHAGDVEGHLSFLEKD  265
                +  ++L +++    G ++G +S LE D
Sbjct  599  VEESKASKRLTKRVQQMIGQIDGLISQLEMD  629


>gi|2492629|sp|Q14957|NMDE3_HUMAN  Glutamate [NMDA] receptor subunit epsilon 3 precursor (N-methyl 
D-aspartate receptor subtype 2C) (NR2C) (NMDAR2C)
Length=1233

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 0/32 (0%)

Query  267   RDKNWGLRLGDRDESGEEGQSRGMQALQGFPG  298
             R +  GL  G RD  G +  SR  +  QGFPG
Sbjct  1188  RGRTLGLGTGYRDSGGLDEISRVARGTQGFPG  1219


>gi|81175034|sp|Q9BYV2|TRI54_HUMAN  Tripartite motif protein 54 (Muscle-specific RING finger protein 
3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) 
(MuRF) (RING finger protein 30)
Length=358

 Score = 27.7 bits (60),  Expect = 7.5
 Identities = 25/115 (21%), Positives = 50/115 (43%), Gaps = 18/115 (15%)

Query  135  VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVR  194
            +EE+ +++   ++  ++ LN + E L   +++   EL   ++   EE  QR       VR
Sbjct  195  MEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQR-------VR  247

Query  195  GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG  249
            G +R           + G HL+   +     ++   E      +QQ ++L  K+G
Sbjct  248  GLIR-----------QYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVG  291


>gi|37999757|sp|Q96PP8|GBP5_HUMAN  Interferon-induced guanylate-binding protein 5 (GTP-binding protein 
5) (Guanine nucleotide-binding protein 5) (GBP-TA antigen)
Length=586

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 29/118 (24%), Positives = 49/118 (41%), Gaps = 7/118 (5%)

Query  42   AKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPH  101
            +KE+V H      T Q     + K  EA+         AQR+  + R+N   +Q   R H
Sbjct  465  SKESVSHAILQ--TDQALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLH  522

Query  102  ADELK----AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNH  155
             ++++    AK +   E+ K +      E   ++  T +   RSL    Q  Q  +N+
Sbjct  523  QEQVRQMEIAKQNWLAEQQKMQ-EQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNN  579


>gi|74760765|sp|Q96CN5|LRC45_HUMAN  Leucine-rich repeat-containing protein 45
Length=670

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 45/222 (20%), Positives = 80/222 (36%), Gaps = 7/222 (3%)

Query  43   KEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVL---RENADSLQASLR  99
            K+  E  + S  +       Q+ L E   +   L    Q  E  L    + A  L   L 
Sbjct  268  KQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLA  327

Query  100  PHADELKAKIDQNVEELKGRLTPYAD-EFKVKID-QTVEELRRSLAPYAQDTQEKLNHQL  157
                E  +   +  +ELK      A+ E K+  D     E    L     + + K   Q 
Sbjct  328  TAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQ  387

Query  158  EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ  217
            E L FQ ++    + A +   A +  +RL       R +L  +     K +  +  HL++
Sbjct  388  EQL-FQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEE  446

Query  218  QVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL  259
              +  + RV+   E    +L +++ +++       G  E  L
Sbjct  447  SEKAMQERVQRL-EAARLSLEEELSRVKAAALSERGQAEEEL  487


>gi|7387887|sp|O00566|MPP10_HUMAN  U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 
10)
Length=681

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query  101  HADELKAK------IDQNVEELKGRLTPYADEFKVKID--QTVEELRRSLAPYAQDTQEK  152
            H DEL +        ++  EEL    T   D+ +   D  Q  E L+R       D + +
Sbjct  283  HDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETE  342

Query  153  LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDV  193
                L      +KKN++E+K+      E++ +++A L +++
Sbjct  343  DTGVLN-----VKKNSDEVKSSFEKRQEKMNEKIASLEKEL  378


>gi|21759268|sp|Q9Y5Q3|MAFB_HUMAN  Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma 
oncogene homolog B)
Length=323

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 1/74 (1%)

Query  109  IDQNVEELKGRLTPYADEFKVKIDQTVEELR-RSLAPYAQDTQEKLNHQLEGLTFQMKKN  167
            +  +V EL   L  +  +  +++ Q    L+ R  A   +  + +  H LE    Q+ + 
Sbjct  217  VSMSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQ  276

Query  168  AEELKARISASAEE  181
             E+LK  +S  A E
Sbjct  277  VEQLKQEVSRLARE  290


>gi|34098767|sp|Q9Y4D1|DAAM1_HUMAN  Disheveled-associated activator of morphogenesis 1
Length=1078

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 21/98 (21%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query  31    MWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLREN  90
             ++D F Q  + AK+  E+++K +  ++  A  + +L E  +  R++    +  E      
Sbjct  975   IFDQFLQAVSEAKQENENMRKKKEEEERRARMEAQLKEQRERERKMRKAKENSEE--SGE  1032

Query  91    ADSLQASLRPHA--DELKAKIDQNVEELKGRLTPYADE  126
              D L ++LR     D+  +K+ +N + +  ++T  + E
Sbjct  1033  FDDLVSALRSGEVFDKDLSKLKRNRKRITNQMTDSSRE  1070


>gi|14424230|sp|Q9Y2G4|ANKR6_HUMAN  Ankyrin repeat domain protein 6
Length=692

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 0/68 (0%)

Query  119  RLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISAS  178
            R  P  ++ + +++ TVEE++  L         KL         QM+   + +  R+SA 
Sbjct  378  RCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAE  437

Query  179  AEELRQRL  186
              E   RL
Sbjct  438  RTECLNRL  445


>gi|82654947|sp|P19013|K2C4_HUMAN  Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) 
(K4)
Length=534

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%)

Query  51   KSELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID  110
            KSE+ + LN + Q    E E +++Q       +    +   ++L+ +      EL+A + 
Sbjct  366  KSEIAE-LNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRV-ELEAALQ  423

Query  111  QNVEELKGRLTPYADEFKVKIDQTVE  136
            Q  EEL   L  Y +   VK+   +E
Sbjct  424  QAKEELARMLREYQELMSVKLALDIE  449


>gi|120487|sp|P15408|FOSL2_HUMAN  Fos-related antigen 2
Length=326

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 33/144 (22%), Positives = 53/144 (36%), Gaps = 26/144 (18%)

Query  75   QLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQT  134
            QL+P  +   R+ RE      A  R    EL  K+    EEL        +E K  + + 
Sbjct  118  QLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEEL--------EEEKSGLQKE  169

Query  135  VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ----------  184
            + EL        Q  +EKL   L       K + EE ++  +   + +R           
Sbjct  170  IAEL--------QKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVV  221

Query  185  RLAPLAEDVRGNLRGNTEGLQKSL  208
            +  PL ED   +     +  Q+S+
Sbjct  222  KQEPLEEDSPSSSSAGLDKAQRSV  245


>gi|20139068|sp|Q96PB7|NOE3_HUMAN  Noelin-3 precursor (Olfactomedin-3) (Optimedin)
Length=478

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 6/101 (5%)

Query  105  LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ--EKLNHQLEGLTF  162
            LKAK  Q  ++ K  +T +  E K K+D+ +  L   L  Y  D +   +   ++  L+ 
Sbjct  124  LKAKFRQIEDDRKTLMTKHFQELKEKMDELL-PLIPVLEQYKTDAKLITQFKEEIRNLSA  182

Query  163  QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEG  203
             +    EE+ A      EEL QR+  L   +R  ++  T G
Sbjct  183  VLTGIQEEIGA---YDYEELHQRVLSLETRLRDCMKKLTCG  220


>gi|45644957|sp|P25067|CO8A2_HUMAN  Collagen alpha-2(VIII) chain precursor (Endothelial collagen)
Length=703

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 14/26 (53%), Positives = 17/26 (65%), Gaps = 2/26 (7%)

Query  275  LGDRDESGEEGQ--SRGMQALQGFPG  298
            LGDR E GE+G+   +G Q L G PG
Sbjct  336  LGDRGEPGEDGEPGEQGPQGLGGPPG  361


>gi|6647481|sp|O14576|DYI1_HUMAN  Dynein intermediate chain 1, cytosolic (DH IC-1) (Cytoplasmic 
dynein intermediate chain 1)
Length=645

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 27/132 (20%), Positives = 61/132 (46%), Gaps = 25/132 (18%)

Query  29   TVMWDYFSQLSNNAKEAVEHLQK-SELTQQLNALFQDKLGEAEQLRRQLTPYAQRMERVL  87
            T+ WD           +V  LQ  SEL ++L+ L   K+ + + L R++  Y++  +  L
Sbjct  123  TLQWD--------TDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPL  174

Query  88   --------RENADSLQASLRPHAD--------ELKAKIDQNVEELKGRLTPYADEFKVKI  131
                     E+ + +++ +   ++        E+K    + + E + +   +++EF +  
Sbjct  175  ATHQSEEDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFF  234

Query  132  DQTVEELRRSLA  143
            D+T+  + R+LA
Sbjct  235  DRTIRVIERALA  246


>gi|23396623|sp|Q9H1H9|KI13A_HUMAN  Kinesin-like protein KIF13A (Kinesin-like protein RBKIN)
Length=1805

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 6/84 (7%)

Query  43   KEAVEHLQKSELTQQLNALFQDKL---GEAEQLRRQLTPYAQRMER---VLRENADSLQA  96
            +  V+ L+K  L ++ +AL + +L    E EQLR+QL+P  Q        L  ++ + Q 
Sbjct  599  QNVVQVLEKQYLEEKRSALEEQRLMYERELEQLRQQLSPDRQPQSSGPDRLAYSSQTAQQ  658

Query  97   SLRPHADELKAKIDQNVEELKGRL  120
             +   A+E      Q + +L+ +L
Sbjct  659  KVTQWAEERDELFRQGLAKLREQL  682


>gi|2497603|sp|Q13753|LAMC2_HUMAN  Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 
100 kDa subunit) (Laminin B2t chain) 
(Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) 
(Large adhesive scatter factor 140 kDa subunit) (Ladsin 
140 kDa subunit)
Length=1193

 Score = 27.3 bits (59),  Expect = 9.8
 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 11/114 (9%)

Query  87   LRENADSLQASLRPHADELK--AKIDQNVEELKGRLTPYADEFKVKIDQTVE--ELRRSL  142
            +++ ADSL   +  H DE K   K   N +E   +L       + K DQ +    L +S 
Sbjct  874  IKQKADSLSTLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSR  933

Query  143  APYAQDTQEKLNHQLEGLTFQMKKNAEELKARI---SASAEELRQRLAPLAEDV  193
            A  A        +++E +     KN  E   ++    A AEE  +RL+ +++ V
Sbjct  934  AQEALSMGNATFYEVESIL----KNLREFDLQVDNRKAEAEEAMKRLSYISQKV  983






  Database: Non-redundant SwissProt sequences
    Posted date:  Mar 15, 2006  2:23 AM
  Number of letters in database: 7,391,856
  Number of sequences in database:  13,628
Lambda     K      H
   0.313    0.130    0.365 
Gapped
Lambda     K      H
   0.267   0.0410    0.140 
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 13628
Number of Hits to DB: 1530
Number of extensions: 49
Number of successful extensions: 0
Number of sequences better than 10: 0
Number of HSP's better than 10 without gapping: 0
Number of HSP's gapped: 0
Number of HSP's successfully gapped: 0
Length of query: 372
Length of database: 7391856
Length adjustment: 98
Effective length of query: 274
Effective length of database: 7391856
Effective search space: 2025368544
Effective search space used: 1659429488
T: 11
A: 40
X1: 16 (7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (20.8 bits)
S2: 59 (27.3 bits)







 


 
Format
  


 


 
Show
  Graphical OverviewLinkoutSequence RetrievalNCBI-giAlignmentPSSMBioseq in HTMLPlain textASN.1XMLformat


 


 

  CDS feature


 


 

  Masking CharacterX for protein, n for nucleotideLower Case
Masking ColorBlackGreyRed



 


 
Number of:
  Descriptions010501002505001000
Alignments010501002505001000



 


 
Alignment view
  PairwisePairwise with identitiesquery-anchored with identitiesquery-anchored without identitiesflat query-anchored with identitiesflat query-anchored without identitiesHit Table


 


 
Format for PSI-BLAST
  with inclusion threshold:


 


 
Limit results by entrez query
   or select from:All organismsViruses [ORGN]Archaea [ORGN]Bacteria [ORGN]Eukaryota [ORGN]Viridiplantae [ORGN]Fungi [ORGN]Metazoa [ORGN]Arthropoda [ORGN]Vertebrata [ORGN]Mammalia [ORGN]Rodentia [ORGN]Primates [ORGN]-------------------Aeropyrum pernix [ORGN]Aquifex aeolicus [ORGN]Arabidopsis thaliana [ORGN]Bacillus subtilis [ORGN]Bos taurus [ORGN]Caenorhabditis elegans [ORGN]Canis familiaris[ORGN]Danio rerio [ORGN]Dictyostelium discoideum [ORGN]Drosophila melanogaster [ORGN]Escherichia coli [ORGN]Gallus gallus [ORGN]Homo sapiens [ORGN]Human immunodeficiency virus type 1 [ORGN]Methanococcus jannaschii [ORGN]Mus musculus [ORGN]Oryctolagus cuniculus [ORGN]Oryza sativa [ORGN]Ovis aries [ORGN]Plasmodium falciparum [ORGN]Rattus norvegicus [ORGN]Saccharomyces cerevisiae [ORGN]Schizosaccharomyces pombe [ORGN]Xenopus tropicalis[ORGN]Simian immunodeficiency virus [ORGN]Sus scrofa[ORGN]Synechocystis PCC6803 [ORGN]Takifugu rubripes [ORGN]Xenopus laevis [ORGN]Zea mays [ORGN]


 


 
Expect value range:
    







 or