CLUSTAL W (1.82) multiple sequence alignment D.erecta -----FNRUTQFSTIFU-------APVAERDAAEE-------LDPNKPALYIEHCRSURV 41 D.yakuba -----FNRUNYFPTIFU-------APVVERDAAEV-------LDPNAPVLYVEHCRSURV 41 D.melanogaster KVRHLLKNSDYFRIMPPKRNKKAEAPIAERDAGEE-------LDPNAPVLYVEHCRSURV 53 D.ananasae ------RAUTLLRTSUQ-------ETAKQDEPPDE-------LDPSQPVLSIEHCRSURV 40 D.virilis ----UMNEISIYIFMQS---------PPESEESKA-------LDPTNPVLYIEHCRSURV 40 SelH -----MAPHGRKRKAGAAP----METVDKREK-----------LAEGATVVIEHCTSURV 40 Anopheles -----MAPR-RKRAAAAKS----TETAAKKAKPEESASTPVEESQDGAYVFIEHCKSUSV 50 : . : :*** ** * D.erecta FRRRAEELHSALQ----ERGLQ-HLQLQLNALGAPRRGAFELSLCAG--MGKQEQVALWS 94 D.yakuba FRRRAEELHSAIR----ERGLQ-HLQLQLNALGAPRRGAFELSLSAG--LGKPEQVALWS 94 D.melanogaster FRRRAEELHSALR----ERGLQ-QLQLQLNALGAPRRGAFELSLSAGG-MGKQEQVALWS 107 D.ananasae FRRRAEELHAALQ----GLGLP-QLQLRLNPSGAPRRGAFELNLSAG---GSEDQVQLWS 92 D.virilis FRRRAEELHSALLSKIQAAGQPFQLQLQLNAQGAPRRGAFELSFAPHPTTNANEQRPIWS 100 SelH YGRHAAALSQALQ----LEAPELPVQVNPS---KPRRGSFEVTLLRS----DNSRVELWT 89 Anopheles FKRKAAEVHSGLC----ELAPEHKFQLVLNEDGKPRRGAFEVSIAKGK---DGEKVLVWS 103 : *:* : .: . .*: . ****:**:.: .: :*: D.erecta GLKRGPPRALKFPTVEEVYDRIVGILGDQ------------------------------- 123 D.yakuba GLKRGPPRALKFPTVEEVYDRIVEILGDQ------------------------------- 123 D.melanogaster GLKRGPPRARKFPTVEEVYDQIVGILGDQQESKEQTNTQKSSKIDLPGSEAIASPKKSES 167 D.ananasae GLKRGPPRALKFPNAEEMHSRIEEILE--------------------------------- 119 D.virilis GLKR-TPRAQKFPNVDEMYQQIVQAFNDLSQKQNKRKRTAQSSTPSPTSTHTLPKRSKAA 159 SelH GIKKGPPRKLKFPEPQEVVEELKKYLS--------------------------------- 116 Anopheles GLPKGPPRKDKFPEPKTILDDVLKVLKKU------------------------------- 132 *: : .** *** . : . : : D.erecta ------------------------------------------------------------ D.yakuba ------------------------------------------------------------ D.melanogaster TEEAQENKAPTSTSTSRKSKKEQKSEEEPTQVDSKEAKQSKELVKTKRQPKAQKKQAKAS 227 D.ananasae ------------------------------------------------------------ D.virilis NADAASNSKASKSA---------------------------------------------- 173 SelH ------------------------------------------------------------ Anopheles ------------------------------------------------------------ D.erecta ------------------------------------ D.yakuba ------------------------------------ D.melanogaster ESQEEVAEDKPPSSQKRKRTTRSSTDEATAGAKRRR 263 D.ananasae ------------------------------------ D.virilis ------------------------------------ SelH ------------------------------------ Anopheles ------------------------------------