CLUSTAL W (1.82) multiple sequence alignment


D.melanogaster      -------------MSYAADVLNSAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 47
D.erecta            -FFASLTPQLUNKMSYAADVLNSAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 59
D.pseudoscura       --KETLLLULUHTMSYAADVLNAAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 58
D.mojavensis        -ITFIULDYFDHKMSYAADVLNAAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 59
D.virilis           TIWFIULDFWN-KMSYAADVLNAAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 59
D.ananasae          --LFVVDQIYQURMSYAADVLNSAHLELHGGGDAELRRPFDPTAHDLDASFRLTRFADLK 58
A.gambiae           --------------DYQQDPM--VHLELTGNTGMVLRRPFDPTAHDLDASFRLTRFADLK 44
SPS2                --MAEASATGACGEAMAAAEGSSGPAGLTLGRSFSNYRPFEPQALGLSPSWRLTGFSGMK 58
D.simulans          -IWNTRNIDRYUSAATSLENDILYSQLFIKPVRRNSRTMFQPEKHGLSPDFQLTKFTTHT 59
D.yakuba            -PSEVLRISISVQVSSLAQNTIFSIQLFLKPVLRISRTMFQPEKHGLEPDFQLTKFTTHT 59
                                               :           *:*   .*...::** *:  .

D.melanogaster      GRGCKVPQDVLSKLVSALQQDYS----------AQDQEPQFLNVAI--------PRIGIG 89
D.erecta            GRGCKVPQDVLSKLVSALQQDYS----------AQDQEPQFLNVAI--------PRIGIG 101
D.pseudoscura       GRGCKVPQDVLSKLVSALQQDYS----------AQDQEPQFLNVAI--------PRIGIG 100
D.mojavensis        GRGCKVPQEVLSKLVSALQQDYS----------AQDQEPQFLNVAI--------PRIGIG 101
D.virilis           GRGCKVPQEVLSKLVSALQQDYS----------AQDQEPQFLNVAI--------PRIGIG 101
D.ananasae          GRGCKVPQDVLSKLVSALQQDYS----------TQDQEPQFLNVAI--------PRIGIG 100
A.gambiae           GRCCKVPKEVLEKLVSSLQQDY-----------MQDPDQPFMPMSS--------PRIGIG 85
SPS2                GUGCKVPQEALLKLLAGLTRPDVRPPLGRGLVGGQEEASQEAGLPAGAGPSPTFPALGIG 118
D.simulans          GUSCKIPQKVLEKYLRGTEIENKNN--DGYLIGERUYYQQIWGLSU-----WEIIFSGSG 112
D.yakuba            GUSCKIPQKVLEKYLRGTEIENKKN--DGYLIGERUYYLQILGLSU-----CEILISGSG 112
                    *  **:*:..* * : .                 :        :.            * *

D.melanogaster      LDCSVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 148
D.erecta            LDCSVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 160
D.pseudoscura       LDCSVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 159
D.mojavensis        LDCAVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 160
D.virilis           LDCAVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 160
D.ananasae          LDCSVIPLR-HGGLCLVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTDCDNMLMLL 159
A.gambiae           LDCSVIPLR-HGGLCMVQTTDFFYPIVDDPYMMGKIACANVLSDLYAMGVTEVDNMLMLL 144
SPS2                MDSCVIPLR-HGGLSLVQTTDFFYPLVEDPYMMGRIACANVLSDLYAMGITECDNMLMLL 177
D.simulans          MDCAVIPLKRHKDYLLIQTVDFFYPMVNDPELLGRIALANVLSDVYAVGVTQFDTVEMIV 172
D.yakuba            MDCAVIPLRRHTDYLLIQTVDFFYPMVNDPELLGRIALANVLSDVYAVGVTQFDTVEMIV 172
                    :*..****: * .  ::**.*****:*:** ::*:** ******:**:*:*: *.: *::

D.melanogaster      AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 205
D.erecta            AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 217
D.pseudoscura       AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 216
D.mojavensis        AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 217
D.virilis           AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 217
D.ananasae          AVSTKMTEKERDVVIPLIMRGFKDSALEAG---TTVTGGQSVVNPWCTIGGVASTICQPN 216
A.gambiae           AVSTKMIEKERDVVIPLIMRGFKDSALEAG---TSVTGGHSVVNPWCTIGGVATTICQQN 201
SPS2                SVSQSMSEEEREKVTPLMVKGFRDAAEEGG---TAVTGGQTVVNPWIIIGGVATVVCQPN 234
D.simulans          STSTSFSEKERDVVIGLVMKGFQNSLKANGYRNTPLIIRQLKINPWCIIGGIATSVCRSE 232
D.yakuba            STSTSFSEKERDTVIALVMQGFQNSLKANGYRNTPLIIRQLKINPWCIIGGIATSVCRSE 232
                    :.* .: *:**: *  *:::**:::    *   *.:   :  :***  ***:*: :*: :

D.melanogaster      EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMN 264
D.erecta            EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMN 276
D.pseudoscura       EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQAERWNRIKLVVSEEDVRKAYHRAMN 275
D.mojavensis        EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMN 276
D.virilis           EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMN 276
D.ananasae          EYIVPDNAVVGDVLVLTKPLGT-QVAVNAHQWIDQPERWNRIKLVVSEEDVRKAYHRAMN 275
A.gambiae           EFIVPDNAVVGDVLVLTKALGT-QVAVNAHQWLDQSERWNRIKLVVSEEDVRKAYHRAMD 260
SPS2                EFIMPDSAVVGDVLVLTKPLGT-QVAVNAHQWLDNPERWNKVKMVVSREEVELAYQEAMF 293
D.simulans          EIILUVLAWDDIFUFIUNTMPIUTVERAARRCVGPHETFGWPNGDGCPPLAAUPDRKVUE 292
D.yakuba            EIILUIKAYDDIFKFIKYILPFUTVERAAWRCFGPHETLRWTNGDGCPPLAAUQDGKVRQ 292
                    * *:   *  . . .:   :    *   * : ..  *     :   .   .     ..

D.melanogaster      SMARLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 316
D.erecta            SMSRLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 328
D.pseudoscura       SMSRLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 327
D.mojavensis        SMSRLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 328
D.virilis           SMSRLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 328
D.ananasae          SMSRLN--------RVAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLP 327
A.gambiae           SMSRLN--------RVAARLMHKYNAHGATDVTGFGLLGHAQTLASHQKNEVSFVIHNLP 312
SPS2                NMATLN--------RTAAGLMHTFNAHAATDITGFGILGHSQNLAKQQRNEVSFVIHNLP 345
D.simulans          TAVRMQUUUYKGNFUNSCEVYDLFEQKWLVLPWYSLFLU-LNNYLFQPPSUCTNIKRTVP 351
D.yakuba            TAVUMUUUUYKRDFUNCCEVYDLFKQKWUVFLWNSLYYFULISFFSRP----FNAQISSA 348
                    .   :           .. : . :: :  .            .   :          . .

D.melanogaster      VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 373
D.erecta            VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 385
D.pseudoscura       VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 384
D.mojavensis        VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 385
D.virilis           VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 385
D.ananasae          VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGYQAWII 384
A.gambiae           VIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLPREQAAAYCKDIEKQ---EGCQAWII 369
SPS2                IIAKMAAVSKASG-RFGLLQGTSAETSGGLLICLPREQAARFCSEIKSSKYGEGHQAWIV 404
D.simulans          LISPDLVYWVT-PIIUHNSKRKRSYSRSTSCPSS--KMYLNSAPWWAKAQSFVLADRWKP 408
D.yakuba            LCHUHYRLWATGPRU----KSSRISTRKGLIPNQUVAHHQKCTKIQHLGGPKHKVSFWQI 404
                    :         :        :     :                             . *

D.melanogaster      GIVE-KGNKTARIIDKPRVIEVPAKD------------------- 398
D.erecta            GIVE-KGNKTARIIDKPRVIEVPAKDUVSIAUPVAIVYLKYRNI- 428
D.pseudoscura       GIVE-KGNKTARIIDKPRVIEVPAKDUMFTFYLYMYGILTULPLS 428
D.mojavensis        GIVE-KGNKTARIIDKPRVIEVPAKDUMFSFILITVIFLHANTU- 428
D.virilis           GIVE-KGNKTARIIDKPRVIEVPAKDUMFSLYISTVIFKKLHTR- 428
D.ananasae          GIVE-KGNKTARIIDKPRVIEVPAKDUIIKPRWLIGFPIRFLSLI 428
A.gambiae           GIVE-KGSRTARIIDKPRVIEVPAKD------------------- 394
SPS2                GIVE-KGNRTARIIDKPRVIEVLPRGATAAVLAPDSSNASSEPSS 448
D.simulans          LVVFUYAFLLMPLINFAATLKKLPTESRNPFKLDM---------- 443
D.yakuba            GRNLWRSLNLPSRUCRRSILPGLURSNQRRAKIFSNWTR------ 443
                          .            :