BLASTP 2.2.10 [Oct-19-2004]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1111085059-15551-8441328611.BLASTQ2

Query= FGENESH:   1   2 exon (s)  62256  -  96756    72 aa,
chain +
         (72 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples 
           2,367,365 sequences; 802,797,248 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs

Taxonomy reports

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|915311|gb|AAA92289.1|  Abl interactor 2                         29   2.3   
gi|32880183|gb|AAP88922.1|  abl-interactor 2 [Homo sapiens] ...    29   2.3   
gi|7839524|gb|AAF70308.1|  Abl-interactor protein 2b [Homo s...    29   2.3   
gi|31541785|ref|NP_005750.3|  abl interactor 2 [Homo sapiens...    29   2.3   
gi|7512270|pir||G01936  Abl binding protein 3 - human >gi|98...    29   2.3   
gi|1491702|emb|CAA64980.1|  argBPIB [Homo sapiens]                 29   2.3   
gi|55959522|emb|CAI17279.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959518|emb|CAI17275.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959521|emb|CAI17278.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959520|emb|CAI17277.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959519|emb|CAI17276.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959517|emb|CAI17274.1|  OTTHUMP00000046074 [Homo sapien...    28   5.1   
gi|55959516|emb|CAI17273.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|55959515|emb|CAI17272.1|  spectrin SH3 domain binding pro...    28   5.1   
gi|23344115|gb|AAN28379.1|  Abl-interactor 1 [Homo sapiens]        28   5.1   
gi|4885611|ref|NP_005461.1|  abl-interactor 1 [Homo sapiens]...    28   5.1   
gi|55962146|emb|CAI16572.1|  phosphoinositide-3-kinase, clas...    27   8.7   
gi|15451926|ref|NP_002637.2|  phosphoinositide-3-kinase, cla...    27   8.7   
gi|7428002|pir||JC5500  phosphoinositide 3-kinase (EC 2.7.1....    27   8.7   
gi|3954946|emb|CAA74194.1|  PI-3 kinase [Homo sapiens]             27   8.7   


Alignments

>gi|915311|gb|AAA92289.1|   Abl interactor 2
          Length = 401

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 337 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 374



>gi|32880183|gb|AAP88922.1|   abl-interactor 2 [Homo sapiens]
 gi|12655167|gb|AAH01439.1|   Abl interactor 2 [Homo sapiens]
          Length = 475

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 411 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 448



>gi|7839524|gb|AAF70308.1|   Abl-interactor protein 2b [Homo sapiens]
 gi|50400673|sp|Q9NYB9|ABI2_HUMAN   Abl-interactor 2 (Abelson interactor 2) (Abi-2) (Abl binding
           protein 3) (AblBP3) (Arg binding protein 1) (ArgBP1)
          Length = 513

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 449 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 486



>gi|31541785|ref|NP_005750.3|   abl interactor 2 [Homo sapiens]
 gi|1491700|emb|CAA64885.1|   Arg protein tyrosine kinase-binding protein [Homo sapiens]
          Length = 475

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 411 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 448



>gi|7512270|pir||G01936   Abl binding protein 3 - human
 gi|987265|gb|AAA75446.1|   Abl binding protein 3
          Length = 390

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 326 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 363



>gi|1491702|emb|CAA64980.1|   argBPIB [Homo sapiens]
          Length = 299

 Score = 28.9 bits (63), Expect = 2.3
 Identities = 11/38 (28%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           PR YL+K++ +Y   ++ +  L+   G  +Y ++K+ D
Sbjct: 235 PRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDD 272



>gi|55959522|emb|CAI17279.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661502|emb|CAH73117.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|4100619|gb|AAD00897.1|   interactor protein AblBP4 [Homo sapiens]
          Length = 451

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 387 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 424



>gi|55959518|emb|CAI17275.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661497|emb|CAH73112.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|7579917|emb|CAB88006.1|   spectrin SH3 binding protein [Homo sapiens]
 gi|50400546|sp|Q8IZP0|ABI1_HUMAN   Abl-interactor 1 (Abelson interactor 1) (Abi-1) (Spectrin SH3
           domain binding protein 1) (Eps8 SH3 domain binding
           protein) (Eps8 binding protein) (e3B1) (Nap1 binding
           protein) (Nap1BP) (Abl binding protein 4) (AblBP4)
          Length = 508

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 444 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 481



>gi|55959521|emb|CAI17278.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661501|emb|CAH73116.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|14164310|dbj|BAB55675.1|   hNap1 Binding Protein [Homo sapiens]
          Length = 452

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 388 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 425



>gi|55959520|emb|CAI17277.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661499|emb|CAH73114.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|2245671|gb|AAB62569.1|   e3B1 [Homo sapiens]
          Length = 480

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 416 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 453



>gi|55959519|emb|CAI17276.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661498|emb|CAH73113.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
          Length = 481

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 417 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 454



>gi|55959517|emb|CAI17274.1|   OTTHUMP00000046074 [Homo sapiens]
 gi|55661500|emb|CAH73115.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|18999471|gb|AAH24254.1|   ABI1 protein [Homo sapiens]
          Length = 476

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 412 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 449



>gi|55959516|emb|CAI17273.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661504|emb|CAH73119.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
          Length = 475

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 411 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 448



>gi|55959515|emb|CAI17272.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|55661503|emb|CAH73118.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
 gi|7839526|gb|AAF70309.1|   Abl-interactor protein 1 long [Homo sapiens]
          Length = 446

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 382 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 419



>gi|23344115|gb|AAN28379.1|   Abl-interactor 1 [Homo sapiens]
          Length = 476

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 412 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 449



>gi|4885611|ref|NP_005461.1|   abl-interactor 1 [Homo sapiens]
 gi|3165429|gb|AAC39757.1|   spectrin SH3 domain binding protein 1 [Homo sapiens]
          Length = 508

 Score = 27.7 bits (60), Expect = 5.1
 Identities = 10/38 (26%), Positives = 23/38 (60%)

Query: 7   PRIYLQKIIDLYTIQENVDHGLAASLGQQLYAVEKDHD 44
           P+ Y++K++ +Y   ++ D  L+   G  +Y ++K+ D
Sbjct: 444 PKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD 481



>gi|55962146|emb|CAI16572.1|   phosphoinositide-3-kinase, class 2, beta polypeptide [Homo sapiens]
          Length = 1634

 Score = 26.9 bits (58), Expect = 8.7
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 14  IIDLYTIQENVDHGLAASLGQQLYAVEKDHDFFIAQIA--VPAADRILVFWKTSYENF 69
           +++LY    N D   A   G + + + ++   F   +A  V A  RI + W TSYE+F
Sbjct: 596 LVELYCNTFNADFQTAVP-GSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDF 652



>gi|15451926|ref|NP_002637.2|   phosphoinositide-3-kinase, class 2, beta polypeptide [Homo sapiens]
          Length = 1634

 Score = 26.9 bits (58), Expect = 8.7
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 14  IIDLYTIQENVDHGLAASLGQQLYAVEKDHDFFIAQIA--VPAADRILVFWKTSYENF 69
           +++LY    N D   A   G + + + ++   F   +A  V A  RI + W TSYE+F
Sbjct: 596 LVELYCNTFNADFQTAVP-GSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDF 652



>gi|7428002|pir||JC5500   phosphoinositide 3-kinase (EC 2.7.1.-) - human
 gi|13632400|sp|O00750|PK3B_HUMAN   Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta
           polypeptide (Phosphoinositide 3-Kinase-C2-beta)
           (PtdIns-3-kinase C2 beta) (PI3K-C2beta) (C2-PI3K)
 gi|2076604|emb|CAA72168.1|   phosphoinositide 3-kinase [Homo sapiens]
          Length = 1634

 Score = 26.9 bits (58), Expect = 8.7
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 14  IIDLYTIQENVDHGLAASLGQQLYAVEKDHDFFIAQIA--VPAADRILVFWKTSYENF 69
           +++LY    N D   A   G + + + ++   F   +A  V A  RI + W TSYE+F
Sbjct: 596 LVELYCNTFNADFQTAVP-GSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDF 652



>gi|3954946|emb|CAA74194.1|   PI-3 kinase [Homo sapiens]
          Length = 1609

 Score = 26.9 bits (58), Expect = 8.7
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 14  IIDLYTIQENVDHGLAASLGQQLYAVEKDHDFFIAQIA--VPAADRILVFWKTSYENF 69
           +++LY    N D   A   G + + + ++   F   +A  V A  RI + W TSYE+F
Sbjct: 571 LVELYCNTFNADFQTAVP-GSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDF 627






  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
    Posted date:  Mar 15, 2005 10:11 AM
  Number of letters in database: 802,797,248
  Number of sequences in database:  2,367,365
  
Lambda     K      H
   0.325    0.140    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,383,611
Number of Sequences: 2367365
Number of extensions: 38355
Number of successful extensions: 152
Number of sequences better than 10.0: 2
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 151
Number of HSP's gapped (non-prelim): 2
length of query: 72
length of database: 46,038,991
effective HSP length: 44
effective length of query: 28
effective length of database: 40,312,787
effective search space: 1128758036
effective search space used: 1128758036
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 58 (26.9 bits)







 


 
Format
  


 


 
Show
  Graphical OverviewLinkoutSequence RetrievalNCBI-giAlignmentPSSMBioseq in HTMLPlain textASN.1XMLformat


 


 
Use new formatter
  Masking CharacterDefault(X for protein, n for nucleotide)Lower Case
Masking ColorBlackGreyRed



 


 
Number of:
  Descriptions01050100250500
Alignments01050100250500



 


 
Alignment view
  PairwisePairwise with identitiesquery-anchored with identitiesquery-anchored without identitiesflat query-anchored with identitiesflat query-anchored without identitiesHit Table


 


 
Format for PSI-BLAST
  with inclusion threshold:


 


 
Limit results by entrez query
   or select from:All organismsViruses [ORGN]Archaea [ORGN]Bacteria [ORGN]Eukaryota [ORGN]Viridiplantae [ORGN]Fungi [ORGN]Metazoa [ORGN]Arthropoda [ORGN]Vertebrata [ORGN]Mammalia [ORGN]Rodentia [ORGN]Primates [ORGN]-------------------Aeropyrum pernix [ORGN]Aquifex aeolicus [ORGN]Arabidopsis thaliana [ORGN]Bacillus subtilis [ORGN]Bos taurus [ORGN]Caenorhabditis elegans [ORGN]Canis familiaris[ORGN]Danio rerio [ORGN]Dictyostelium discoideum [ORGN]Drosophila melanogaster [ORGN]Escherichia coli [ORGN]Gallus gallus [ORGN]Homo sapiens [ORGN]Human immunodeficiency virus type 1 [ORGN]Methanococcus jannaschii [ORGN]Mus musculus [ORGN]Oryctolagus cuniculus [ORGN]Oryza sativa [ORGN]Ovis aries [ORGN]Plasmodium falciparum [ORGN]Rattus norvegicus [ORGN]Saccharomyces cerevisiae [ORGN]Schizosaccharomyces pombe [ORGN]Xenopus tropicalis[ORGN]Simian immunodeficiency virus [ORGN]Sus scrofa[ORGN]Synechocystis PCC6803 [ORGN]Takifugu rubripes [ORGN]Xenopus laevis [ORGN]Zea mays [ORGN]


 


 
Expect value range:
    







 or