RPS-BLAST 2.2.9 [May-01-2004]
Query= local sequence:
hg16_dna_2|geneid_v1.2_predicted_protein_2|282_AA
(281 letters)
Database: cdd.v2.03
| PSSMs producing significant alignments: |
Score
(bits) |
E
value |
| |
| gnl|CDD|24046 |
pfam05822, UMPH-1, Pyrimidine 5'-nucleotidase (UMPH-1). This f... |
252 |
4e-68 |
gnl|CDD|24046,
pfam05822, UMPH-1, Pyrimidine 5'-nucleotidase (UMPH-1). This family
consists of several eukaryotic pyrimidine 5'-nucleotidase proteins.
P5'N-1, also known as uridine monophosphate hydrolase-1 (UMPH-1), is a
member of a large functional group of enzymes, characterised by the
ability to dephosphorylate nucleic acids. P5'N-1 catalyses the
dephosphorylation of pyrimidine nucleoside monophosphates to the
corresponding nucleosides. Deficiencies in this proteins function can
lead to several different disorders in humans.
CD-Length = 247 residues, 100.0% aligned
Score = 252 bits (644), Expect = 4e-68
Query: 91 MTLSRFSYKGKRCPTCHNSIDNCQLITDECRKKLLQLKKKYYAIEVDPVLTVEEKYPYMV 150
Sbjct: 1 YTLSRFAYNGERCPTSHGIFDNCKRLKEECRQKLVDLKHKYYPIEIDPHLTIEEKIPYMV 60
Query: 151 EC---------------DVLEEVIRQ---------------------------------- 161
Sbjct: 61 EWWTKSHSLLVNQKFSKNTIEQIVRQSTIMLKDGYEDFFEALQQHGIPLFIFSAGIGNIL 120
Query: 162 ------AGVYHPNVKVVSNFMDFDETGVLKGFKGVLIHIFNKHDGALRN-TEYFNQLKDN 214
Sbjct: 121 EEVLRQAGVIHPNVKVVSNFMDFDEDGNLKGFKGPLIHTFNKNSSVLQNETSYFHDLAGR 180
Query: 215 SNIILLGDSQGDLRMADGVANVEHILKVGYLNDRVDELLEKYMDSYDIVLVQDESLEVAN 274
Sbjct: 181 VNIILLGDSIGDLHMADGVPRVGHILKIGYLNDSVDETLEKYMDSYDIVLVKDETLDVVN 240
Query: 275 SILQKIL 281
Sbjct: 241 KILDIIL 247
Citing CD-Search:
Marchler-Bauer A, Bryant SH (2004),
"CD-Search: protein domain annotations on the fly.",
Nucleic Acids Res. 32:W327-331.
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