>gi|23822263|sp|Q9HCN3|TME8_HUMAN Transmembrane protein 8 precursor (M83 protein) Length = 771 Score = 1392 bits (3602), Expect = 0.0 Identities = 680/747 (91%), Positives = 682/747 (91%), Gaps = 16/747 (2%) Query: 21 KVGLVSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITV 80 +VGLVSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITV Sbjct: 41 EVGLVSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITV 100 Query: 81 HFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTTPRSNASVNVSHPAPGDWFVAAHLP 140 HFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLST PRSNASVNVSHPAPGDWFVAAHLP Sbjct: 101 HFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTAPRSNASVNVSHPAPGDWFVAAHLP 160 Query: 141 PSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTR 200 PSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTR Sbjct: 161 PSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTR 220 Query: 201 ELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDRWLQV 260 ELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDRWLQV Sbjct: 221 ELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDRWLQV 280 Query: 261 TAESLVGPLGTVAFSAVAALTACRPRSVTIQPLLXXXXXXXXXXXXGLLSPSPDHQDLGR 320 TAESLVGPLGTVAFSAVAALTACRPRSVT+QPLL GLLSPSPDHQDLGR Sbjct: 281 TAESLVGPLGTVAFSAVAALTACRPRSVTVQPLLQSSQNQSFNASSGLLSPSPDHQDLGR 340 Query: 321 SGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNTGMDSGGSL 380 SGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNTGMDSGGSL Sbjct: 341 SGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNTGMDSGGSL 400 Query: 381 TISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIP 440 TISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIP Sbjct: 401 TISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIP 460 Query: 441 YPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYAS 500 YPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYAS Sbjct: 461 YPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYAS 520 Query: 501 CSCKAGWRGWSCTDNSXXXXXXXXXXXXXXXXXSNLMFLAPIAVSVRRFFLVEASVYAYT 560 CSCKAGWRGWSCTDNS SNLMFLAPIAVSVRRFFLVEASVYAYT Sbjct: 521 CSCKAGWRGWSCTDNSTAQTVAQQRAATLLLTLSNLMFLAPIAVSVRRFFLVEASVYAYT 580 Query: 561 MFFSTGCGVGGQDRAHGASPQFYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILC 620 MFFST FYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILC Sbjct: 581 MFFST----------------FYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILC 624 Query: 621 MARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQCY 680 MARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQCY Sbjct: 625 MARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQCY 684 Query: 681 PTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHIXXXXXXXXXXXXXXXXX 740 PTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHI Sbjct: 685 PTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHILLAGSAALLLPPPDQPA 744 Query: 741 XXWACSQKFPCHYQICKNDREELYAVT 767 WACSQKFPCHYQICKNDREELYAVT Sbjct: 745 EPWACSQKFPCHYQICKNDREELYAVT 771
>gi|23822261|sp|Q9ESN3|TME8_MOUSE Transmembrane protein 8 precursor (M83 protein) Length = 769 Score = 1087 bits (2811), Expect = 0.0 Identities = 529/747 (70%), Positives = 581/747 (77%), Gaps = 17/747 (2%) Query: 21 KVGLVSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITV 80 + GLVSEHFSQAPQ+LSFYSWYGS RLF FRVPPD VLLRWLL VS+ S +CTD EITV Sbjct: 40 EAGLVSEHFSQAPQKLSFYSWYGSTRLFHFRVPPDTVLLRWLLHVSQGS-PSCTDEEITV 98 Query: 81 HFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTTPRSNASVNVSHPAPGDWFVAAHLP 140 HFR GAPPVINPLGTSFPD+T SF + LST N SVN+SHPAPGDWF+ AHLP Sbjct: 99 HFRYGAPPVINPLGTSFPDNTLSHASFHIRALLSTLMLDNTSVNISHPAPGDWFLVAHLP 158 Query: 141 PSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTR 200 PSSQKI++KG PTCAY+FQP++LV RVVE+S +EPDVPLPQTLLS+PSYLK+FVP+YT+ Sbjct: 159 PSSQKIQVKGFVPTCAYIFQPDMLVMRVVEVSTLEPDVPLPQTLLSYPSYLKIFVPEYTQ 218 Query: 201 ELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDRWLQV 260 EL LEL+ CVS+ S GCPVR+TVG TLP NFQ+VLTCTG C LLL SPPW RWLQV Sbjct: 219 ELRLELQGCVSSVSPGCPVRVTVGATTLPRNFQRVLTCTGLAPSCHLLLSSPPWGRWLQV 278 Query: 261 TAESLVGPLGTVAFSAVAALTACRPRSVTIQPLLXXXXXXXXXXXXGLLSPSPDHQDLGR 320 T ESL P TV F+A A T CRP SVTI L+ LS S H+DLGR Sbjct: 279 TFESLAEPHVTVGFTAKAVFTVCRPWSVTIHHLIQNNPNQTYDTSAIQLSQSAVHRDLGR 338 Query: 321 SGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNTGMDSGGSL 380 S RVD PFCL NYPV RED DVVSVHFQPL+ V V S PSVM+LRL+TGMDSGGS Sbjct: 339 SSRVDSGPFCLLNYPVLREDTDVVSVHFQPLNGAFVLVHSSMPSVMQLRLDTGMDSGGSF 398 Query: 381 TISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIP 440 I LR NKTE+ N T+V ACVNAASPFL FNTSLNCTTAFFQGYP+ L A S ANLI+P Sbjct: 399 IIVLRTNKTEVTNGTLVAACVNAASPFLSFNTSLNCTTAFFQGYPMFLRASSHMANLIMP 458 Query: 441 YPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYAS 500 +PETDNWYLSLQL+CPE+ EDCEQAVV VET LYLVPCLNDCGPYGQCLLLRR+ Y+YA Sbjct: 459 FPETDNWYLSLQLVCPESPEDCEQAVVRVETILYLVPCLNDCGPYGQCLLLRRYGYVYAG 518 Query: 501 CSCKAGWRGWSCTDNSXXXXXXXXXXXXXXXXXSNLMFLAPIAVSVRRFFLVEASVYAYT 560 CSCKAGWRGWSCTDNS SNLMFLAPIA+S+ R FLVEASVY YT Sbjct: 519 CSCKAGWRGWSCTDNSTAQTVAQQRAAALLLTLSNLMFLAPIAISLHRSFLVEASVYFYT 578 Query: 561 MFFSTGCGVGGQDRAHGASPQFYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILC 620 MFFST FYHACDQPGEAVLCILSYDTLQYCDFLGSGA+ WVTILC Sbjct: 579 MFFST----------------FYHACDQPGEAVLCILSYDTLQYCDFLGSGASTWVTILC 622 Query: 621 MARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQCY 680 MARLKT+LK VL +LGTLVIAMSLQ+DRRG+WN++GPC+FAFVIMASMW YRCGHR QCY Sbjct: 623 MARLKTILKQVLLVLGTLVIAMSLQMDRRGIWNLMGPCVFAFVIMASMWIYRCGHRGQCY 682 Query: 681 PTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHIXXXXXXXXXXXXXXXXX 740 PTSWQRW FYLLPG+SMASVGIA+YTSMMTSDNYYYTHSIWHI Sbjct: 683 PTSWQRWVFYLLPGISMASVGIAMYTSMMTSDNYYYTHSIWHILLAGSAAFLLPPREEKA 742 Query: 741 XXWACSQKFPCHYQICKNDREELYAVT 767 WAC QKFPCHYQIC+NDR+ELY VT Sbjct: 743 GSWACLQKFPCHYQICRNDRDELYTVT 769
>gi|22096361|sp|P34576|MUA3_CAEEL Transmembrane cell adhesion receptor mua-3 precursor Length = 3767 Score = 38.1 bits (87), Expect = 0.089 Identities = 27/123 (21%), Positives = 56/123 (45%), Gaps = 16/123 (13%) Query: 389 TEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIPYPETDNWY 448 TE++N V + +P L ++ G + + R+ + +P +D +Y Sbjct: 3099 TELKNAFVTAEVNDIVNPVL-------MNASYDTGLLFNTTVHFRKGMVHVP---SDAYY 3148 Query: 449 LSLQLMCPENAEDCEQAVVHVETTLY--LVPCL-NDCGPYGQCLLLRRHSYLYASCSCKA 505 ++ + EN + + +++ T PC NDC P+G+C+ + +++Y C C Sbjct: 3149 QLIKYVTKENNNEVGDSELYLNPTQPDPFNPCFKNDCDPHGKCIEISKYAY---KCECGV 3205 Query: 506 GWR 508 G+R Sbjct: 3206 GYR 3208
>gi|2506798|sp|P08922|ROS_HUMAN Proto-oncogene tyrosine-protein kinase ROS precursor (c-ros-1) Length = 2347 Score = 33.9 bits (76), Expect = 1.7 Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 18/92 (19%) Query: 69 SGAACTDAEITVHFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTTPRSNASVNVSHP 128 SG C E+ V FR P + V F++ +S +N + Sbjct: 1054 SGKCCNKNEVVVEFRWNKPK----------HENGVLTKFEIFYNISNQSITNKTCE---- 1099 Query: 129 APGDWFVAAHLPPSSQKIELKGLAPTCAYVFQ 160 DW +A ++ PS +L+G++P C FQ Sbjct: 1100 ---DW-IAVNVTPSVMSFQLEGMSPRCFIAFQ 1127
>gi|3915888|sp|P24821|TENA_HUMAN Tenascin precursor (TN) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Miotendinous antigen) (Glioma-associated-extracellular matrix antigen) (GP 150-225) (Tenascin-C) (TN-C) Length = 2201 Score = 33.9 bits (76), Expect = 1.7 Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 21/67 (31%) Query: 452 QLMCPEN--AEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRG 509 Q +C E EDC Q + C NDC G+C+ C C+ G++G Sbjct: 422 QCVCDEGYTGEDCSQ-----------LRCPNDCHSRGRCV--------EGKCVCEQGFKG 462 Query: 510 WSCTDNS 516 + C+D S Sbjct: 463 YDCSDMS 469
>gi|41019514|sp|Q8P3H6|HEMZ_XANCP Ferrochelatase (Protoheme ferro-lyase) (Heme synthetase) Length = 318 Score = 33.9 bits (76), Expect = 1.7 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 17/67 (25%) Query: 440 PYPETDNWYL------SLQLMCPENAEDC-----EQAVVHVET------TLYLVPCLNDC 482 PY E W L S L+CP A DC E A+ ET TL +PCLND Sbjct: 245 PYAEPTLWALAEGGVRSFDLVCPGFATDCLETLEEVALGFAETLAERGATLSYIPCLNDS 304 Query: 483 GPYGQCL 489 + Q L Sbjct: 305 TTHAQAL 311
>gi|46577418|sp|Q80X80|TMM24_MOUSE Transmembrane protein 24 Length = 706 Score = 33.5 bits (75), Expect = 2.2 Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 11/113 (9%) Query: 108 QVGVPLSTTPRSNASVNVSHPAPGDWFVAAHLPPSSQKIELK-----GLAPTCAYVFQPE 162 +V P+S T +S A+V++ + V LPP+ ++ L+ GL + A+ +PE Sbjct: 160 EVRFPISVTQQSPAAVSME-----TYHVTLTLPPTQLEVSLEEIPDEGLLVSWAFTDRPE 214 Query: 163 LLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTRELLLELRDCVSNGSL 215 L + + ++ E D P+ L + +K + +++ LR C + G L Sbjct: 215 LSLKVLPKLQTRERDEEQPE-LSTVEELIKDAIVSTQPAMMVNLRACSAPGGL 266
>gi|27735174|sp|O06318|CUT3_MYCTU Probable cutinase cut3 precursor Length = 262 Score = 33.1 bits (74), Expect = 2.9 Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 73 CTDAEITVHFRSGAPPVINPLGTSFPDDTAVQPSFQVGV 111 C DAE+T +G PP I +G +F D Q ++GV Sbjct: 44 CPDAEVTFARGTGEPPGIGRVGQAFVDSLRQQTGMEIGV 82
>gi|33302576|sp|P24014|SLIT_DROME Slit protein precursor Length = 1504 Score = 33.1 bits (74), Expect = 2.9 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 477 PCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSCTDN 515 P N C +C+ + + SC C+AG+ G +CTDN Sbjct: 1054 PEFNPCANGAKCM----DHFTHYSCDCQAGFHGTNCTDN 1088
>gi|20455036|sp|Q90Y57|JG1A_BRARE Jagged 1a precursor (Jagged1a) (Jagged1) Length = 1242 Score = 33.1 bits (74), Expect = 2.9 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 5/36 (13%) Query: 482 CGPYGQCLLLRRHSYL--YASCSCKAGWRGWSCTDN 515 CGP+G+C R HS+ + SC C+ G+ G C +N Sbjct: 600 CGPHGRC---RSHSHAGGHFSCDCQDGFTGTYCHEN 632
Score = 33.1 bits (74), Expect = 2.9 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 14/63 (22%) Query: 455 CPE--NAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSC 512 CP+ + ++CE+A + PCLN G C+ S L C C AGW G SC Sbjct: 325 CPDGYSGQNCERA----DNACLSEPCLNG----GLCV----ESSLGFECQCAAGWTGPSC 372 Query: 513 TDN 515 N Sbjct: 373 NIN 375
>gi|12643637|sp|O75173|ATS4_HUMAN ADAMTS-4 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 4) (ADAM-TS 4) (ADAM-TS4) (Aggrecanase 1) (ADMP-1) Length = 837 Score = 33.1 bits (74), Expect = 2.9 Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 16/82 (19%) Query: 52 VPPDAVLLRWLLQVSRESGAACTDAEITVHFRSGAPPVINPLGTSFPDDTAVQPSFQVGV 111 V P AV LR+ SGA ++ H P + L P DT ++ SF V Sbjct: 752 VLPGAVSLRY-------SGATAASETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPR 804 Query: 112 PLSTTPRSNASVNVSHPAPGDW 133 P +TPR P P DW Sbjct: 805 PTPSTPR---------PTPQDW 817
>gi|20455035|sp|Q90Y54|JG1B_BRARE Jagged 1b precursor (Jagged1b) (Jagged3) Length = 1213 Score = 32.3 bits (72), Expect = 4.9 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 3/36 (8%) Query: 480 NDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSCTDN 515 N CGP+G+C R + +C C+ G+RG C +N Sbjct: 594 NVCGPHGRC---RSQAGGQFTCECQEGFRGTYCHEN 626
>gi|6175057|sp|Q29116|TENA_PIG Tenascin precursor (TN) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Miotendinous antigen) (Glioma-associated-extracellular matrix antigen) (GP 150-225) (Tenascin-C) (TN-C) (P230) Length = 1746 Score = 32.3 bits (72), Expect = 4.9 Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 21/67 (31%) Query: 452 QLMCPEN--AEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRG 509 Q +C E EDC Q + C NDC G+C+ R C C+ G++G Sbjct: 422 QCVCDEGRTGEDCSQ-----------LRCPNDCHGRGRCVQGR--------CECEHGFQG 462 Query: 510 WSCTDNS 516 + C++ S Sbjct: 463 YDCSEMS 469
>gi|34925036|sp|O73791|TIE2_BRARE Tyrosine-protein kinase receptor Tie-2 precursor Length = 1116 Score = 32.3 bits (72), Expect = 4.9 Identities = 18/40 (45%), Positives = 19/40 (47%), Gaps = 16/40 (40%) Query: 475 LVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSCTD 514 LV CL D PYG CSC +GWRG SC D Sbjct: 280 LVFCLRD--PYG--------------CSCASGWRGLSCND 303
>gi|117422|sp|P10040|CRB_DROME Crumbs protein precursor (95F) Length = 2139 Score = 32.3 bits (72), Expect = 4.9 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 19/58 (32%) Query: 455 CPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSC 512 C N ++C++ PCLN G+CL H+Y + +C C GW G C Sbjct: 424 CQTNVDECDKN-----------PCLNG----GRCL----HTYGWYTCQCLDGWGGEIC 462
Score = 31.6 bits (70), Expect = 8.4 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 16/61 (26%) Query: 452 QLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWS 511 Q +CPEN + C Q PC N G+C+ L Y C C GW G + Sbjct: 601 QCLCPEN-KVCNQCATQ--------PCQNG----GECVDLPNGDY---ECKCTRGWTGRT 644 Query: 512 C 512 C Sbjct: 645 C 645
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.324 0.137 0.449 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,235,987 Number of Sequences: 164271 Number of extensions: 670269 Number of successful extensions: 1882 Number of sequences better than 10.0: 2 Number of HSP's better than 10.0 without gapping: 0 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 1881 Number of HSP's gapped (non-prelim): 2 length of query: 767 length of database: 60,490,055 effective HSP length: 118 effective length of query: 649 effective length of database: 41,106,077 effective search space: 26677843973 effective search space used: 26677843973 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 70 (31.6 bits)