>gi|6016293|sp|O43365|HXA3_HUMAN Homeobox protein Hox-A3 (Hox-1E) Length = 443 Score = 402 bits (1033), Expect = e-113 Identities = 214/316 (67%), Positives = 220/316 (69%), Gaps = 9/316 (2%) Query: 27 NANQQPYPASAALGADGEYHRPACSLQ-------SPSSAGGHPKAHELSESCAGDKSPPG 79 NA+ P PA+AA + P + Q S + + ESCAGDKSPPG Sbjct: 130 NASNNPTPANAAKSP--LLNSPTVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPG 187 Query: 80 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 139 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK Sbjct: 188 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 247 Query: 140 KDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNXXXXXXXXXXXXXXXXQGTYGL 199 KDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVN QGTYGL Sbjct: 248 KDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGL 307 Query: 200 XXXXXXXXXXXXXXXXXXQKRYTXXXXXXXXTPDYDPHAHGLQGNGSYGTPHIQGSPVFV 259 QKRYT TPDYDPHAHGLQGNGSYGTPHIQGSPVFV Sbjct: 308 PPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHGLQGNGSYGTPHIQGSPVFV 367 Query: 260 GGSYVEPMSNSGPALFGLTHLPHAASGAMDYXXXXXXXXXXXXXXXXXXXXXTYTDLTGH 319 GGSYVEPMSNSGPALFGLTHLPHAASGAMDY TYTDLTGH Sbjct: 368 GGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGHHHGPGPGEPHPTYTDLTGH 427 Query: 320 HPSQGRIQEAPKLTHL 335 HPSQGRIQEAPKLTHL Sbjct: 428 HPSQGRIQEAPKLTHL 443
Score = 155 bits (391), Expect = 2e-38 Identities = 75/84 (89%), Positives = 76/84 (90%), Gaps = 1/84 (1%) Query: 1 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 60 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG Sbjct: 1 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGG 60 Query: 61 HPKAHELSESCAGDKS-PPGQASS 83 HPKAHELSE+C S PP Q S Sbjct: 61 HPKAHELSEACLRTLSAPPSQPPS 84
>gi|123268|sp|P14651|HXB3_HUMAN Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7) Length = 431 Score = 240 bits (613), Expect = 4e-64 Identities = 142/270 (52%), Positives = 166/270 (61%), Gaps = 23/270 (8%) Query: 73 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 132 GDKSPPG A+SKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL+ERQIKIWFQ Sbjct: 178 GDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQ 237 Query: 133 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP--GAGGYLNSMHSLVNXXXXXXXXXXXXX 190 NRRMKYKKDQK KG+ +SSGG SP+ SP P G++N++HS+ Sbjct: 238 NRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSM--TPSYESPSPPAFG 295 Query: 191 XXXQGTYGLXXXXXXXXXXXXXXXXXXQKRYTXXXXXXXXTPDYDPHAHGLQGN-GSYGT 249 Q Y L ++Y P+Y+PH LQ N G+YGT Sbjct: 296 KAHQNAYAL-----PSNYQPPLKGCGAPQKYP-----PTPAPEYEPHV--LQANGGAYGT 343 Query: 250 PHIQGSPVFV-GGSYVEPM-SNSGPALFGLTHLPHAASGAMDYXXXXXXXXXXXXXXXXX 307 P +QGSPV+V GG Y +P+ +GP+L+GL HL H SG +DY Sbjct: 344 PTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDY--NGAPPMAPSQHHGPC 401 Query: 308 XXXXTYTDLTGHH--PSQGRIQEAPKLTHL 335 TYTDL+ HH P QGRIQEAPKLTHL Sbjct: 402 EPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 431
Score = 72.8 bits (177), Expect = 2e-13 Identities = 44/102 (43%), Positives = 58/102 (56%), Gaps = 11/102 (10%) Query: 1 MQKATYYDSSA--IYGGYP-YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSS 57 MQKATYYD++A ++GGY Y +NGF ++ QP P AA +G+Y R ACSLQS + Sbjct: 1 MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQP-PFQAATHLEGDYQRSACSLQSLGN 59 Query: 58 AGGHPKAHELSESCAGD-------KSPPGQASSKRARTAYTS 92 A H K+ EL+ SC +PPG A T+ TS Sbjct: 60 AAPHAKSKELNGSCMRPGLAPETLSAPPGSPPPSAAPTSATS 101
>gi|6166222|sp|P31249|HXD3_HUMAN Homeobox protein Hox-D3 (Hox-4A) Length = 416 Score = 227 bits (578), Expect = 5e-60 Identities = 135/269 (50%), Positives = 156/269 (57%), Gaps = 20/269 (7%) Query: 69 ESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIK 128 ESC DKSPPG AS KR RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIK Sbjct: 166 ESCE-DKSPPGPAS-KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIK 223 Query: 129 IWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSL--VNXXXXXXXXX 186 IWFQNRRMKYKKDQK KG+L S QSP RSP GA G++ L V Sbjct: 224 IWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSP 283 Query: 187 XXXXXXXQGTYGLXXXXXXXXXXXXXXXXXXQKRYTXXXXXXXXTPDYDPHAHGLQGNGS 246 YGL QKRY P+++PH G G Sbjct: 284 PAFAKSQPNMYGL-----AAYTAPLSSCLPQQKRY--------AAPEFEPHPMASNG-GG 329 Query: 247 YGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYXXXXXXXXXXXXXXXX 306 + + ++QGSPV+VGG++VE M+ + +F L HL H +S ++DY Sbjct: 330 FASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDY--SCAAQIPGNHHHGP 387 Query: 307 XXXXXTYTDLTGHHPSQGRIQEAPKLTHL 335 TYTDL+ HH SQGR+ EAPKLTHL Sbjct: 388 CDPHPTYTDLSAHHSSQGRLPEAPKLTHL 416
Score = 56.6 bits (135), Expect = 1e-08 Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 16/100 (16%) Query: 1 MQKATYYDSSAIYGGYPY-QAANGFAYNANQQPYPASAALGA-DGEYHRPACSLQS--PS 56 MQKA YY++ ++GGY Y + + + Y+ QPYP AA + D +Y ACS+QS P Sbjct: 1 MQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPL 60 Query: 57 SAGGHPKAHELSESC-----------AGDKSPPGQASSKR 85 A H K EL+ SC G PPG S ++ Sbjct: 61 RAPAH-KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 99
>gi|123270|sp|P14652|HXB2_HUMAN Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8) Length = 356 Score = 110 bits (276), Expect = 5e-25 Identities = 59/120 (49%), Positives = 76/120 (63%), Gaps = 9/120 (7%) Query: 47 RPACSLQSPSSAGGHPKAHELSESCAGDKSPP-GQASSKRARTAYTSAQLVELEKEFHFN 105 +P+ S SPS A A + G P G ++R RTAYT+ QL+ELEKEFHFN Sbjct: 106 KPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFN 165 Query: 106 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGA 165 +YLCRPRRVE+A LL+LTERQ+K+WFQNRRMK+K+ + + + P P PGA Sbjct: 166 KYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHR--------EPPDGEPACPGA 217
>gi|6016292|sp|O43364|HXA2_HUMAN Homeobox protein Hox-A2 Length = 376 Score = 107 bits (267), Expect = 6e-24 Identities = 62/137 (45%), Positives = 80/137 (58%), Gaps = 19/137 (13%) Query: 16 YPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDK 75 YP+ A P A+AA A PAC H ++ E+++ G Sbjct: 95 YPWMKEKKAAKKTALLPAAAAAATAAATG---PACL--------SHKESLEIADGSGG-- 141 Query: 76 SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 135 S+R RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A LL+LTERQ+K+WFQNRR Sbjct: 142 ------GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRR 195 Query: 136 MKYKKDQKGKGMLTSSG 152 MK+K+ + K S G Sbjct: 196 MKHKRQTQCKENQNSEG 212
>gi|1708540|sp|P52945|IPF1_HUMAN Insulin promoter factor-1 (IPF-1) (Pancreas/duodenum homeobox-1) (PDX-1) (Islet/duodenum homeobox-1) (IDX-1) (Somatostatin transactivating factor-1) (STF-1) (Insulin upstream factor-1) (IUF-1) (Glucose-sensitive factor) (GSF) Length = 283 Score = 107 bits (267), Expect = 6e-24 Identities = 67/152 (44%), Positives = 81/152 (53%), Gaps = 20/152 (13%) Query: 32 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYT 91 P+P A G E +R +Q P KAH AG +KR RTAYT Sbjct: 99 PFPEGAEPGVLEEPNR----VQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYT 154 Query: 92 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ---KGKGML 148 AQL+ELEKEF FN+Y+ RPRRVE+A +LNLTER IKIWFQNRRMK+KK++ +G G Sbjct: 155 RAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTA 214 Query: 149 TSSGGQSPSRS-------------PVPPGAGG 167 GG + P PP GG Sbjct: 215 VGGGGVAEPEQDCAVTSGEELLALPPPPPPGG 246
>gi|400000|sp|P09067|HXB5_HUMAN Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1) Length = 269 Score = 103 bits (258), Expect = 6e-23 Identities = 60/129 (46%), Positives = 73/129 (56%), Gaps = 14/129 (10%) Query: 41 ADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPP--------------GQASSKRA 86 A E A L SPS A P+ S + ++P KRA Sbjct: 138 ASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGKRA 197 Query: 87 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKG 146 RTAYT Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD K K Sbjct: 198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKS 257 Query: 147 MLTSSGGQS 155 M ++ G + Sbjct: 258 MSLATAGSA 266
>gi|20141491|sp|P09016|HXD4_HUMAN Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13) Length = 255 Score = 102 bits (253), Expect = 2e-22 Identities = 53/83 (63%), Positives = 62/83 (74%), Gaps = 3/83 (3%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 KR+RTAYT Q++ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD K Sbjct: 155 KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK 214 Query: 144 ---GKGMLTSSGGQSPSRSPVPP 163 KG +SS S S V P Sbjct: 215 LPNTKGRSSSSSSSSSCSSSVAP 237
>gi|52788238|sp|P20719|HXA5_HUMAN Homeobox protein Hox-A5 (Hox-1C) Length = 270 Score = 101 bits (252), Expect = 3e-22 Identities = 50/75 (66%), Positives = 58/75 (77%) Query: 79 GQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 138 G KRARTAYT Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+ Sbjct: 191 GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 250 Query: 139 KKDQKGKGMLTSSGG 153 KKD K K M ++ G Sbjct: 251 KKDNKLKSMSMAAAG 265
>gi|6166217|sp|Q00056|HXA4_HUMAN Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4) Length = 320 Score = 100 bits (250), Expect = 5e-22 Identities = 65/140 (46%), Positives = 81/140 (57%), Gaps = 14/140 (10%) Query: 34 PASAALGADGEYHRPACSL----QSPSSAGG-----HPKAHELSESCAGDKSPPGQASSK 84 PA+ + A G PAC L +SP G +P ++ S G+ K Sbjct: 161 PATPGVPAGGS--APACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNGGEP--K 216 Query: 85 RARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKG 144 R+RTAYT Q++ELEKEFHFNRYL R RR+E+A+ L L+ERQ+KIWFQNRRMK+KKD K Sbjct: 217 RSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKL 276 Query: 145 KGMLTSSGGQSPSRSPVPPG 164 S S S S PPG Sbjct: 277 PNTKMRS-SNSASASAGPPG 295
>gi|547692|sp|P17483|HXB4_HUMAN Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6) Length = 251 Score = 100 bits (249), Expect = 7e-22 Identities = 52/81 (64%), Positives = 61/81 (75%), Gaps = 1/81 (1%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 KR+RTAYT Q++ELEKEFH+NRYL R RRVE+A+ L L+ERQIKIWFQNRRMK+KKD K Sbjct: 163 KRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHK 222 Query: 144 GKGMLTSSGGQSPSRSPVPPG 164 SGG + S PPG Sbjct: 223 LPNTKIRSGGAAGSAGG-PPG 242
>gi|17378648|sp|Q9GZZ0|HXD1_HUMAN Homeobox protein Hox-D1 Length = 328 Score = 99.4 bits (246), Expect = 2e-21 Identities = 68/175 (38%), Positives = 95/175 (54%), Gaps = 20/175 (11%) Query: 6 YYDSSAIY-GGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSP--------- 55 +Y +SA++ GG + + Y A +P P A L A + H A SP Sbjct: 133 HYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSV 192 Query: 56 SSAGGHPKAHELSE--------SCAGDKSPPGQASSKRA-RTAYTSAQLVELEKEFHFNR 106 S A G P A E S G + G AS A RT +++ QL ELEKEFHFN+ Sbjct: 193 SPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNK 252 Query: 107 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPV 161 YL R RR+E+AN L+L + Q+KIWFQNRRMK KK ++ +G+L ++ +P + P+ Sbjct: 253 YLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKRER-EGLLATAIPVAPLQLPL 306
>gi|3915721|sp|P31268|HXA7_HUMAN Homeobox protein Hox-A7 (Hox-1A) (Hox 1.1) Length = 230 Score = 99.4 bits (246), Expect = 2e-21 Identities = 68/158 (43%), Positives = 84/158 (53%), Gaps = 27/158 (17%) Query: 26 YNAN----QQPYPASAALGADGEYHRPACS-------LQSPSSAGGHPKAHELSESCAGD 74 YN N Q P+ + LGAD + P S L S + G K E + A + Sbjct: 55 YNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAE 114 Query: 75 KS---PPGQASS----KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQI 127 + P SS KR R YT Q +ELEKEFHFNRYL R RR+E+A+ L LTERQI Sbjct: 115 ANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQI 174 Query: 128 KIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGA 165 KIWFQNRRMK+KK+ K +G P+ + P GA Sbjct: 175 KIWFQNRRMKWKKEHKDEG---------PTAAAAPEGA 203
>gi|232262|sp|Q00444|HXC5_HUMAN Homeobox protein Hox-C5 (Hox-3D) (CP11) Length = 222 Score = 96.3 bits (238), Expect = 1e-20 Identities = 46/66 (69%), Positives = 53/66 (80%) Query: 80 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 139 + KR+RT+YT Q +ELEKEFHFNRYL R RR+E+AN L L ERQIKIWFQNRRMK+K Sbjct: 152 ETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWK 211 Query: 140 KDQKGK 145 KD K K Sbjct: 212 KDSKMK 217
>gi|27923786|sp|Q9H4S2|GSHI_HUMAN Homeobox protein GSH-1 Length = 264 Score = 95.1 bits (235), Expect = 3e-20 Identities = 48/91 (52%), Positives = 60/91 (65%) Query: 74 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 D S SSKR RTA+TS QL+ELE+EF N YL R RR+E+A LNL+E+Q+KIWFQN Sbjct: 138 DSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197 Query: 134 RRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 164 RR+K+KK+ KG GG + P G Sbjct: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQG 228
>gi|123279|sp|P09017|HXC4_HUMAN Homeobox protein Hox-C4 (Hox-3E) (CP19) Length = 264 Score = 95.1 bits (235), Expect = 3e-20 Identities = 56/119 (47%), Positives = 71/119 (59%), Gaps = 7/119 (5%) Query: 31 QPYPASAALGADGEYHRPACSLQSP----SSAGGHPKAHELSESCAGDKSPPGQ--ASSK 84 +P P S A A PACS +P S+A P + + P K Sbjct: 99 EPAPLSGA-SASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPK 157 Query: 85 RARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 R+R AYT Q++ELEKEFH+NRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD + Sbjct: 158 RSRAAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHR 216
>gi|20138327|sp|Q9BZM3|GSH2_HUMAN Homeobox protein GSH-2 Length = 304 Score = 94.4 bits (233), Expect = 5e-20 Identities = 56/128 (43%), Positives = 78/128 (60%), Gaps = 5/128 (3%) Query: 17 PYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKS 76 P Q + A A A+AALG ++H P C+ + + A + H L+ + Sbjct: 141 PQQPGSAAAAAAAAAAAAAAAALGHP-QHHAPVCTATTYNVADPR-RFHCLTMGGSDASQ 198 Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 P + KR RTA+TS QL+ELE+EF N YL R RR+E+A LNL+E+Q+KIWFQNRR+ Sbjct: 199 VP---NGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRV 255 Query: 137 KYKKDQKG 144 K+KK+ KG Sbjct: 256 KHKKEGKG 263
>gi|123255|sp|P09629|HXB7_HUMAN Homeobox protein Hox-B7 (Hox-2C) (HHO.C1) Length = 217 Score = 94.4 bits (233), Expect = 5e-20 Identities = 68/187 (36%), Positives = 86/187 (45%), Gaps = 46/187 (24%) Query: 6 YYDSSAIY--GGYPYQAANGFAYNANQQPYPASAAL-----------GADGEYHRPACSL 52 Y SS+++ G +P Q + FA N + Y A + G G + A + Sbjct: 14 YPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAGSMQGLYPGGGGMAGQSAAGV 73 Query: 53 QS------PSSAGGH--PKAHELSESCAGDKSPPGQASS--------------------- 83 + PSS H P LS C GD + A Sbjct: 74 YAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSS 133 Query: 84 ----KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 139 KR R YT Q +ELEKEFH+NRYL R RR+E+A+ L LTERQIKIWFQNRRMK+K Sbjct: 134 GTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWK 193 Query: 140 KDQKGKG 146 K+ K G Sbjct: 194 KENKTAG 200
>gi|17378385|sp|P31267|HXA6_HUMAN Homeobox protein Hox-A6 (Hox-1B) Length = 233 Score = 93.6 bits (231), Expect = 8e-20 Identities = 50/90 (55%), Positives = 60/90 (66%), Gaps = 3/90 (3%) Query: 70 SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 129 SCAG + +R R YT Q +ELEKEFHFNRYL R RR+E+AN L LTERQIKI Sbjct: 145 SCAGAVYG---SHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKI 201 Query: 130 WFQNRRMKYKKDQKGKGMLTSSGGQSPSRS 159 WFQNRRMK+KK+ K SG S +++ Sbjct: 202 WFQNRRMKWKKENKLINSTQPSGEDSEAKA 231
>gi|20141493|sp|P09630|HXC6_HUMAN Homeobox protein Hox-C6 (Hox-3C) (HHO.C8) (CP25) Length = 235 Score = 93.6 bits (231), Expect = 8e-20 Identities = 46/79 (58%), Positives = 56/79 (70%) Query: 81 ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 A +R R Y+ Q +ELEKEFHFNRYL R RR+E+AN L LTERQIKIWFQNRRMK+KK Sbjct: 139 ADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 198 Query: 141 DQKGKGMLTSSGGQSPSRS 159 + L+ GG + + S Sbjct: 199 ESNLTSTLSGGGGGATADS 217
>gi|123271|sp|P14653|HXB1_HUMAN Homeobox protein Hox-B1 (Hox-2I) Length = 301 Score = 92.0 bits (227), Expect = 2e-19 Identities = 49/89 (55%), Positives = 57/89 (64%), Gaps = 10/89 (11%) Query: 76 SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 135 S PG S RT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Q+KIWFQNRR Sbjct: 196 SEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRR 255 Query: 136 MKYKKDQKGKGMLTSSGGQSPSRSPVPPG 164 MK KK ++ GG+ P P PPG Sbjct: 256 MKQKKRER-------EGGRVP---PAPPG 274
>gi|45644931|sp|P50219|HLXB9_HUMAN Homeobox protein HB9 Length = 403 Score = 90.5 bits (223), Expect = 7e-19 Identities = 67/158 (42%), Positives = 79/158 (50%), Gaps = 32/158 (20%) Query: 15 GYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHE-------- 66 G P QAA Y Y A+AA A H PA S P G HP AH Sbjct: 153 GLPAQAA---LYGHPVYGYSAAAAAAALAGQH-PALSYSYPQVQGAHP-AHPADPIKLGA 207 Query: 67 --------LSESCAGDKSPP-----GQASS------KRARTAYTSAQLVELEKEFHFNRY 107 L S AG P QA S +R RTA+TS QL+ELE +F N+Y Sbjct: 208 GTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKY 267 Query: 108 LCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 L RP+R E+A L LTE Q+KIWFQNRRMK+K+ +K K Sbjct: 268 LSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAK 305
>gi|13124738|sp|P17509|HXB6_HUMAN Homeobox protein Hox-B6 (Hox-2B) (Hox-2.2) (HU-2) Length = 224 Score = 90.1 bits (222), Expect = 9e-19 Identities = 42/62 (67%), Positives = 50/62 (80%) Query: 82 SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 S +R R YT Q +ELEKEFH+NRYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ Sbjct: 145 SGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 204 Query: 142 QK 143 K Sbjct: 205 SK 206
>gi|123286|sp|P28356|HXD9_HUMAN Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2) Length = 342 Score = 88.2 bits (217), Expect = 4e-18 Identities = 49/110 (44%), Positives = 65/110 (59%), Gaps = 1/110 (0%) Query: 36 SAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQL 95 S+ A ++ P CSL+ P+ +L + + + S+++ R YT Q Sbjct: 229 SSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNP-EANWIHARSTRKKRCPYTKYQT 287 Query: 96 VELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 +ELEKEF FN YL R RR E+A +LNLTERQ+KIWFQNRRMK KK K K Sbjct: 288 LELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEK 337
>gi|6166216|sp|P49639|HXA1_HUMAN Homeobox protein Hox-A1 (Hox-1F) Length = 335 Score = 87.8 bits (216), Expect = 5e-18 Identities = 61/151 (40%), Positives = 79/151 (52%), Gaps = 23/151 (15%) Query: 15 GYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHP---------KAH 65 G +Q+ YN + P AS H+ AC +SP+S P K + Sbjct: 165 GQEHQSLALATYNNSLSPLHAS---------HQEAC--RSPASETSSPAQTFDWMKVKRN 213 Query: 66 ELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTER 125 G+ GQ ++ RT +T+ QL ELEKEFHFN+YL R RRVE+A L L E Sbjct: 214 PPKTGKVGEYGYLGQPNA--VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNET 271 Query: 126 QIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 156 Q+KIWFQNRRMK KK +K +G+L S P Sbjct: 272 QVKIWFQNRRMKQKKREK-EGLLPISPATPP 301
>gi|20141507|sp|P17482|HXB9_HUMAN Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5) Length = 250 Score = 85.9 bits (211), Expect = 2e-17 Identities = 57/136 (41%), Positives = 70/136 (51%), Gaps = 19/136 (13%) Query: 30 QQPYPASAALGADGEYHRPACSLQSPSSAGGHPKA-------HELSESCAG--DKSPPGQ 80 Q A LGA GE + S ++ G + ++ C G DK P Q Sbjct: 113 QAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQ 172 Query: 81 A----------SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIW 130 SS++ R YT Q +ELEKEF FN YL R RR E+A LLNL+ERQ+KIW Sbjct: 173 TNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIW 232 Query: 131 FQNRRMKYKKDQKGKG 146 FQNRRMK KK K +G Sbjct: 233 FQNRRMKMKKMNKEQG 248
>gi|20141537|sp|P31274|HXC9_HUMAN Homeobox protein Hox-C9 (Hox-3B) Length = 260 Score = 84.7 bits (208), Expect = 4e-17 Identities = 57/149 (38%), Positives = 72/149 (48%), Gaps = 19/149 (12%) Query: 16 YPYQAANGFAYNANQQPYPASAA--------------LGADGEYH-RPACSLQSPSSAGG 60 +P A G Y YP A G+ GE R +L SP + Sbjct: 106 FPSFPAGGRHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRAPQTLPSPEADAL 165 Query: 61 HPKAHELSESCAGDKSPPGQ----ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEM 116 H+ ++ +P S+++ R YT Q +ELEKEF FN YL R RR E+ Sbjct: 166 AGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEV 225 Query: 117 ANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 A +LNLTERQ+KIWFQNRRMK KK K K Sbjct: 226 ARVLNLTERQVKIWFQNRRMKMKKMNKEK 254
>gi|6166219|sp|P31269|HXA9_HUMAN Homeobox protein Hox-A9 (Hox-1G) Length = 272 Score = 84.7 bits (208), Expect = 4e-17 Identities = 51/108 (47%), Positives = 62/108 (57%), Gaps = 11/108 (10%) Query: 48 PACSLQSPSSAGGHPKAHELSESCAGDKSP--PGQA--------SSKRARTAYTSAQLVE 97 P + S G + + +ES GDK P P S+++ R YT Q +E Sbjct: 162 PPVDREKQPSEGAFSENNAENES-GGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLE 220 Query: 98 LEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 LEKEF FN YL R RR E+A LLNLTERQ+KIWFQNRRMK KK K + Sbjct: 221 LEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDR 268
>gi|1709079|sp|P50222|MEOX2_HUMAN Homeobox protein MOX-2 (Mesenchyme homeobox 2) (Growth arrest-specific homeobox) Length = 303 Score = 84.3 bits (207), Expect = 5e-17 Identities = 47/112 (41%), Positives = 66/112 (58%), Gaps = 1/112 (0%) Query: 34 PASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSA 93 P AA A G+Y R A S G + + S+S G+ + ++ RTA+T Sbjct: 138 PTGAAC-APGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKE 196 Query: 94 QLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 Q+ ELE EF + YL R RR E+A L+LTERQ+K+WFQNRRMK+K+ + G+ Sbjct: 197 QIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKRVKGGQ 248
>gi|20141506|sp|P17481|HXB8_HUMAN Homeobox protein Hox-B8 (Hox-2D) (Hox-2.4) Length = 243 Score = 84.0 bits (206), Expect = 7e-17 Identities = 55/139 (39%), Positives = 69/139 (49%), Gaps = 12/139 (8%) Query: 4 ATYYDSSAIYGGYPYQAANGF-AYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHP 62 A + D YG P Q + F A + + Y A G S QSPS P Sbjct: 77 ACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFP 136 Query: 63 KAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 122 P A +R R Y+ Q +ELEKEF FN YL R RR+E+++ L L Sbjct: 137 WMR-----------PQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGL 185 Query: 123 TERQIKIWFQNRRMKYKKD 141 TERQ+KIWFQNRRMK+KK+ Sbjct: 186 TERQVKIWFQNRRMKWKKE 204
>gi|2506529|sp|Q07687|DLX2_HUMAN Homeobox protein DLX-2 Length = 328 Score = 82.0 bits (201), Expect = 3e-16 Identities = 58/157 (36%), Positives = 75/157 (47%), Gaps = 10/157 (6%) Query: 14 GGYPYQAANGFAYNA---NQQPYPASAA--LGADGEYHRPACSLQSPSSAGGHPKAHELS 68 GG PY + Y A N PY A ++ LG Y A S S A P+ +L Sbjct: 80 GGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGYTAAYTSYAPYGTSSSPANNEPEKEDLE 139 Query: 69 ESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIK 128 P + ++ RT Y+S QL L++ F +YL P R E+A L LT+ Q+K Sbjct: 140 PEIRIVNGKPKKV--RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVK 197 Query: 129 IWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGA 165 IWFQNRR K+KK K G + S Q P S PP A Sbjct: 198 IWFQNRRSKFKKMWK-SGEIPSE--QHPGASASPPCA 231
>gi|20141612|sp|Q9NYD6|HXC10_HUMAN Homeobox protein Hox-C10 Length = 342 Score = 81.6 bits (200), Expect = 3e-16 Identities = 43/100 (43%), Positives = 60/100 (60%), Gaps = 2/100 (2%) Query: 41 ADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEK 100 ++ E R + SP ++ K +E+ G+ S ++ R YT Q +ELEK Sbjct: 228 SESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTA--KSGRKKRCPYTKHQTLELEK 285 Query: 101 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 EF FN YL R RR+E++ +NLT+RQ+KIWFQNRRMK KK Sbjct: 286 EFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325
>gi|13124744|sp|P31270|HXA11_HUMAN Homeobox protein Hox-A11 (Hox-1I) Length = 313 Score = 81.3 bits (199), Expect = 4e-16 Identities = 47/105 (44%), Positives = 66/105 (62%), Gaps = 9/105 (8%) Query: 36 SAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQL 95 +AA + E R S SP S+ GH +E AG S GQ + K+ R YT Q+ Sbjct: 203 TAAAAEEKERRRRPESSSSPESSSGH------TEDKAGGSS--GQRTRKK-RCPYTKYQI 253 Query: 96 VELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ELE+EF F+ Y+ + +R++++ +LNLT+RQ+KIWFQNRRMK KK Sbjct: 254 RELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 298
>gi|12230077|sp|Q14549|GBX1_HUMAN Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1) Length = 139 Score = 80.9 bits (198), Expect = 6e-16 Identities = 46/97 (47%), Positives = 62/97 (63%), Gaps = 5/97 (5%) Query: 64 AHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT 123 A E + AG +P G+ S+R RTA+TS QL+ELEKEFH +YL R ++A+ L L+ Sbjct: 20 AEEGAPVTAGVTAPGGK--SRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLS 77 Query: 124 ERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 160 E Q+KIWFQNRR K+K+ + G SS P R+P Sbjct: 78 EVQVKIWFQNRRAKWKRIKAGN---VSSRSGEPVRNP 111
>gi|1709078|sp|P50221|MEOX1_HUMAN Homeobox protein MOX-1 (Mesenchyme homeobox 1) Length = 254 Score = 80.5 bits (197), Expect = 7e-16 Identities = 45/117 (38%), Positives = 68/117 (58%), Gaps = 2/117 (1%) Query: 40 GADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELE 99 G G+ + S + + + E S++ P G + +++ RTA+T QL ELE Sbjct: 128 GGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELE 187 Query: 100 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 156 EF + YL R RR E+A L+L+ERQ+K+WFQNRRMK+K+ + G+ + S GQ P Sbjct: 188 AEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPI--SPNGQDP 242
>gi|12644203|sp|P31277|HXD11_HUMAN Homeobox protein Hox-D11 (Hox-4F) Length = 338 Score = 80.1 bits (196), Expect = 1e-15 Identities = 48/114 (42%), Positives = 67/114 (58%), Gaps = 19/114 (16%) Query: 40 GADGEYHRPACSLQSPSSAGGHPKAHELSESCAGD-KSPPGQAS------------SKRA 86 GA G P C+ +P G PK +E GD + PPG+A S++ Sbjct: 216 GAGGGGGSP-CTKATP---GSEPKG--AAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKK 269 Query: 87 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 R YT Q+ ELE+EF FN Y+ + +R++++ +LNLT+RQ+KIWFQNRRMK KK Sbjct: 270 RCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323
>gi|13124745|sp|P31273|HXC8_HUMAN Homeobox protein Hox-C8 (Hox-3A) Length = 242 Score = 79.7 bits (195), Expect = 1e-15 Identities = 52/136 (38%), Positives = 67/136 (49%), Gaps = 14/136 (10%) Query: 8 DSSAIYG--GYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAH 65 D+S YG P Q+ G A+ YP + S + SS G Sbjct: 84 DASKFYGYEALPRQSLYGAQQEASVVQYPDCKS------------SANTNSSEGQGHLNQ 131 Query: 66 ELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTER 125 S S P + R Y+ Q +ELEKEF FN YL R RR+E+++ L LTER Sbjct: 132 NSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTER 191 Query: 126 QIKIWFQNRRMKYKKD 141 Q+KIWFQNRRMK+KK+ Sbjct: 192 QVKIWFQNRRMKWKKE 207
>gi|13124737|sp|P13378|HXD8_HUMAN Homeobox protein Hox-D8 (Hox-4E) (Hox-5.4) Length = 290 Score = 79.7 bits (195), Expect = 1e-15 Identities = 37/65 (56%), Positives = 47/65 (72%) Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 P +R R Y+ Q +ELEKEF FN YL R RR+E+++ L LTERQ+KIWFQNRRM Sbjct: 191 PQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRM 250 Query: 137 KYKKD 141 K+KK+ Sbjct: 251 KWKKE 255
>gi|12644308|sp|P52951|GBX2_HUMAN Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2) Length = 348 Score = 79.3 bits (194), Expect = 2e-15 Identities = 43/93 (46%), Positives = 60/93 (64%), Gaps = 5/93 (5%) Query: 68 SESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQI 127 S AG + G+ ++R RTA+TS QL+ELEKEFH +YL R ++A+ L L+E Q+ Sbjct: 234 SSGAAGSTTSTGK--NRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQV 291 Query: 128 KIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 160 KIWFQNRR K+K+ + G +S PSR+P Sbjct: 292 KIWFQNRRAKWKRVKAGN---ANSKTGEPSRNP 321
>gi|1345720|sp|P47902|CDX1_HUMAN Homeobox protein CDX-1 (Caudal-type homeobox protein 1) Length = 265 Score = 78.6 bits (192), Expect = 3e-15 Identities = 62/167 (37%), Positives = 80/167 (47%), Gaps = 18/167 (10%) Query: 8 DSSAIYGGYPYQ-----AANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGH- 61 D +A YG P A+ F + P PA G G +P +PSS G Sbjct: 71 DWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPGP-GLLAQPLGGPGTPSSPGAQR 129 Query: 62 PKAHELSES--CAGDKSPPGQASSK-RARTAYTSAQLVELEKEFHFNRYLCRPRRVEMAN 118 P +E AG G+ +K + R YT Q +ELEKEFH++RY+ R+ E+A Sbjct: 130 PTPYEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAA 189 Query: 119 LLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGA 165 L LTERQ+KIWFQNRR K +K K K Q + P PP A Sbjct: 190 NLGLTERQVKIWFQNRRAKERKVNKKK--------QQQQQPPQPPMA 228
>gi|3287858|sp|O43248|HXC11_HUMAN Homeobox protein Hox-C11 Length = 304 Score = 78.2 bits (191), Expect = 4e-15 Identities = 53/144 (36%), Positives = 81/144 (56%), Gaps = 17/144 (11%) Query: 6 YYDSSAIYGGYPYQ----AANGFAYNANQQPYPAS-----AALGADGEYHRPACSLQSPS 56 ++D++ GG P + G A + P PAS A GA+ E + PS Sbjct: 154 FFDNAYCGGGDPPAEPPCSGKGEAKGEPEAP-PASGLASRAEAGAEAEAEEENTN---PS 209 Query: 57 SAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEM 116 S+G AH +++ A +P + K+ R Y+ Q+ ELE+EF FN Y+ + +R+++ Sbjct: 210 SSGS---AHSVAKEPAKGAAPNAPRTRKK-RCPYSKFQIRELEREFFFNVYINKEKRLQL 265 Query: 117 ANLLNLTERQIKIWFQNRRMKYKK 140 + +LNLT+RQ+KIWFQNRRMK KK Sbjct: 266 SRMLNLTDRQVKIWFQNRRMKEKK 289
>gi|123289|sp|P28358|HXD10_HUMAN Homeobox protein Hox-D10 (Hox-4D) (Hox-4E) Length = 340 Score = 77.8 bits (190), Expect = 5e-15 Identities = 36/59 (61%), Positives = 45/59 (76%) Query: 82 SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 S ++ R YT Q +ELEKEF FN YL R RR+E++ +NLT+RQ+KIWFQNRRMK KK Sbjct: 265 SGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKK 323
>gi|20141282|sp|Q99626|CDX2_HUMAN Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3) Length = 313 Score = 77.8 bits (190), Expect = 5e-15 Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 37/179 (20%) Query: 20 AANGFAYNANQQPYPASAALGADGEYH--------------RPACS---LQSPSSAGGHP 62 AAN A+ N A+ + +YH P+C+ LQ+ + P Sbjct: 88 AANAVAHGLNGGSPAAAMGYSSPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGP 147 Query: 63 KAHELSES----------CAGDKSPPGQASSKRART--------AYTSAQLVELEKEFHF 104 A +E C + P Q+ + +T YT Q +ELEKEFH+ Sbjct: 148 AATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHY 207 Query: 105 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP 163 +RY+ R+ E+A L L+ERQ+KIWFQNRR K +K K K L Q P + P PP Sbjct: 208 SRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKK--LQQQQQQQPPQPPPPP 264
>gi|13124743|sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL) Length = 393 Score = 77.4 bits (189), Expect = 6e-15 Identities = 47/125 (37%), Positives = 64/125 (51%), Gaps = 12/125 (9%) Query: 28 ANQQPYPASAALGADG------EYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQA 81 A P P + A G+ G E H + + + S A + G+ A Sbjct: 252 ALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAA 311 Query: 82 ------SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 135 S ++ R YT Q +ELEKEF FN YL R RR+E++ ++LT+RQ+KIWFQNRR Sbjct: 312 NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRR 371 Query: 136 MKYKK 140 MK KK Sbjct: 372 MKLKK 376
>gi|6016210|sp|P78367|NK32_HUMAN Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) Length = 333 Score = 75.1 bits (183), Expect = 3e-14 Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 5/125 (4%) Query: 27 NANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRA 86 + ++ P +G G + CS G E E A K KR+ Sbjct: 155 SGDRSPRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKP-----RKKRS 209 Query: 87 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKG 146 R A++ AQ+ ELE+ F+ RYL P R ++A L LTE Q+KIWFQNRR K K+ Q Sbjct: 210 RAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAAD 269 Query: 147 MLTSS 151 +L S+ Sbjct: 270 LLASA 274
>gi|13431329|sp|Q9UMQ3|BARX2_HUMAN Homeobox protein BarH-like 2 Length = 254 Score = 74.7 bits (182), Expect = 4e-14 Identities = 40/105 (38%), Positives = 62/105 (59%), Gaps = 9/105 (8%) Query: 54 SPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRR 113 S + GG A SE+ ++ P Q +R+RT +T QL+ LEK+F +YL P R Sbjct: 82 SAEAPGGEALASSESET---EQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDR 138 Query: 114 VEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSR 158 +++A L LT+ Q+K W+QNRRMK+KK M+ G ++P++ Sbjct: 139 LDLAQSLGLTQLQVKTWYQNRRMKWKK------MVLKGGQEAPTK 177
>gi|38605720|sp|P56177|DLX1_HUMAN Homeobox protein DLX-1 Length = 255 Score = 73.9 bits (180), Expect = 7e-14 Identities = 56/160 (35%), Positives = 73/160 (45%), Gaps = 22/160 (13%) Query: 15 GYPY----QAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSES 70 GYPY + Y ++ Q YP SA+L A S +S GG E+ + Sbjct: 68 GYPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGADSEKSTVVEGG-----EVRFN 122 Query: 71 CAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIW 130 G K ++ RT Y S QL L + F +YL P R E+A L LT+ Q+KIW Sbjct: 123 GKGKKI-------RKPRTIYCSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIW 175 Query: 131 FQNRRMKYKKDQKGKG------MLTSSGGQSPSRSPVPPG 164 FQN+R K+KK K G L + S PVPPG Sbjct: 176 FQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPG 215
>gi|12231013|sp|Q03828|EVX2_HUMAN Homeobox even-skipped homolog protein 2 (EVX-2) Length = 476 Score = 73.6 bits (179), Expect = 9e-14 Identities = 41/98 (41%), Positives = 53/98 (54%), Gaps = 4/98 (4%) Query: 49 ACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASS----KRARTAYTSAQLVELEKEFHF 104 A + +S G H S G + G S +R RTA+T Q+ LEKEF+ Sbjct: 150 AAGTTTSASGSGLGSLHGGSGGSGGSAALGGSGSGADQVRRYRTAFTREQIARLEKEFYR 209 Query: 105 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 Y+ RPRR E+A LNL E IK+WFQNRRMK K+ + Sbjct: 210 ENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQR 247
>gi|1352398|sp|P49640|EVX1_HUMAN Homeobox even-skipped homolog protein 1 (EVX-1) Length = 407 Score = 73.2 bits (178), Expect = 1e-13 Identities = 42/110 (38%), Positives = 56/110 (50%), Gaps = 5/110 (4%) Query: 33 YPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTS 92 Y S G++ P ++P S GG G + +R RTA+T Sbjct: 138 YQHSKGSGSEALVGSPNGGSETPKSNGGSGGG-----GSQGTLACSASDQMRRYRTAFTR 192 Query: 93 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 Q+ LEKEF+ Y+ RPRR E+A LNL E IK+WFQNRRMK K+ + Sbjct: 193 EQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQR 242
>gi|3024482|sp|P78337|PITX1_HUMAN Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot) Length = 314 Score = 73.2 bits (178), Expect = 1e-13 Identities = 41/105 (39%), Positives = 57/105 (54%), Gaps = 4/105 (3%) Query: 59 GGHPKAHELSES----CAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRV 114 GG PK E S + C G P + +R RT +TS QL ELE F NRY R Sbjct: 61 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE 120 Query: 115 EMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRS 159 E+A NLTE ++++WF+NRR K++K ++ + + GG P S Sbjct: 121 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFS 165
>gi|3023467|sp|O14627|CDX4_HUMAN Homeobox protein CDX-4 (Caudal-type homeobox protein 4) Length = 284 Score = 72.4 bits (176), Expect = 2e-13 Identities = 41/85 (48%), Positives = 53/85 (62%), Gaps = 2/85 (2%) Query: 82 SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 + ++ R YT Q +ELEKEFH NRY+ R+ E+A L L+ERQ+KIWFQNRR K +K Sbjct: 172 TKEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKM 231 Query: 142 QKGK-GMLTSSGGQSPSRS-PVPPG 164 K K +SGG S S + PG Sbjct: 232 IKKKISQFENSGGSVQSDSDSISPG 256
>gi|6016205|sp|O95096|NKX22_HUMAN Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) Length = 273 Score = 72.0 bits (175), Expect = 3e-13 Identities = 49/145 (33%), Positives = 69/145 (47%), Gaps = 12/145 (8%) Query: 26 YNANQQPYPASAALGADGEYHRPACSLQSP----SSAGGHPKAHELSESCAGDKSPPG-- 79 Y+++ PY A +Y + +P SS P A E ++ DK PG Sbjct: 66 YDSSDNPYTRWLASTEGLQYSLHGLAAGAPPQDSSSKSPEPSADESPDN---DKETPGGG 122 Query: 80 --QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 ++ R ++ AQ ELE+ F RYL P R +A+L+ LT Q+KIWFQN R K Sbjct: 123 GDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYK 182 Query: 138 YKKDQKGKGMLTSSGGQSPSRSPVP 162 K+ + KGM + SP R VP Sbjct: 183 MKRARAEKGMEVTP-LPSPRRVAVP 206
>gi|27923815|sp|Q8TAU0|NKX23_HUMAN Homeobox protein Nkx-2.3 (Homeobox protein NKX-2.3) (Homeobox protein NK-2 homolog C) Length = 364 Score = 71.6 bits (174), Expect = 3e-13 Identities = 43/115 (37%), Positives = 59/115 (51%), Gaps = 12/115 (10%) Query: 49 ACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYL 108 +C L+ G KA E SE P S ++ R ++ AQ+ ELE+ F RYL Sbjct: 121 SCQLKKSLETAGDCKAAEESER-------PKPRSRRKPRVLFSQAQVFELERRFKQQRYL 173 Query: 109 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP 163 P R +A+ L LT Q+KIWFQNRR K K+ ++ K + G +P P PP Sbjct: 174 SAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSL--ELGAHAP---PPPP 223
>gi|17377578|sp|Q99801|NKX31_HUMAN Homeobox protein Nkx-3.1 Length = 234 Score = 71.2 bits (173), Expect = 5e-13 Identities = 45/131 (34%), Positives = 65/131 (49%), Gaps = 16/131 (12%) Query: 32 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYT 91 P A + E H + L S +++G P+ + K P KR+R A++ Sbjct: 84 PEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTP------KQP-----QKRSRAAFS 132 Query: 92 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSS 151 Q++ELE++F +YL P R +A L LTE Q+KIWFQNRR K K+ Q L+S Sbjct: 133 HTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQ-----LSSE 187 Query: 152 GGQSPSRSPVP 162 G S +P Sbjct: 188 LGDLEKHSSLP 198
>gi|12644329|sp|P56178|DLX5_HUMAN Homeobox protein DLX-5 Length = 289 Score = 71.2 bits (173), Expect = 5e-13 Identities = 51/158 (32%), Positives = 68/158 (43%), Gaps = 18/158 (11%) Query: 9 SSAIYGG------YPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHP 62 +SA YG Y Y NG +A P A A YH+ + SA P Sbjct: 62 TSASYGKALNPYQYQYHGVNG---SAGSYPAKAYADYSYASSYHQYGGAYNRVPSATNQP 118 Query: 63 KAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 122 + P + ++ RT Y+S QL L++ F +YL P R E+A L L Sbjct: 119 EKEVTEPEVRMVNGKPKKV--RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGL 176 Query: 123 TERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP 160 T+ Q+KIWFQN+R K KK K +G P SP Sbjct: 177 TQTQVKIWFQNKRSKIKKIMK-------NGEMPPEHSP 207
>gi|3913487|sp|O60479|DLX3_HUMAN Homeobox protein DLX-3 Length = 287 Score = 70.9 bits (172), Expect = 6e-13 Identities = 57/179 (31%), Positives = 77/179 (43%), Gaps = 24/179 (13%) Query: 13 YGGYPY-QAANGFAYN--------------ANQQPYPASAALGADGEYHRPACSLQSPSS 57 Y G PY Q N + Y+ + + Y A+ G Y Q P S Sbjct: 51 YSGQPYGQTVNPYTYHHQFNLNGLAGTGAYSPKSEYTYGASYRQYGAYREQPLPAQDPVS 110 Query: 58 AGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA 117 P+A + K ++ RT Y+S QL L++ F +YL P R E+A Sbjct: 111 VKEEPEAEVRMVNGKPKKV-------RKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163 Query: 118 NLLNLTERQIKIWFQNRRMKYKKDQK-GKGMLTSSGGQSPSRS-PVPPGAGGYLNSMHS 174 L LT+ Q+KIWFQNRR K+KK K G+ L S S S + PP + S HS Sbjct: 164 AQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHS 222
>gi|20141538|sp|P31275|HXC12_HUMAN Homeobox protein Hox-C12 (Hox-3F) Length = 282 Score = 70.9 bits (172), Expect = 6e-13 Identities = 39/90 (43%), Positives = 55/90 (61%), Gaps = 7/90 (7%) Query: 51 SLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCR 110 SL SP + GG S +G P + S++ R Y+ QL ELE EF N ++ R Sbjct: 189 SLVSPLNPGG-------GLSASGAPWYPINSRSRKKRKPYSKLQLAELEGEFLVNEFITR 241 Query: 111 PRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 RR E+++ LNL+++Q+KIWFQNRRMK K+ Sbjct: 242 QRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271
>gi|1708211|sp|P52952|NK25_HUMAN Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E) (Cardiac-specific homeobox) (Homeobox protein CSX) Length = 324 Score = 69.7 bits (169), Expect = 1e-12 Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 13/126 (10%) Query: 18 YQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSP 77 + AA F A P PA E C+LQ KA EL ++ A + Sbjct: 86 FPAAPAFYPRAYSDPDPAKDPRAEKKEL----CALQ---------KAVELEKTEADNAER 132 Query: 78 PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 P ++ R ++ AQ+ ELE+ F RYL P R ++A++L LT Q+KIWFQNRR K Sbjct: 133 PRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYK 192 Query: 138 YKKDQK 143 K+ ++ Sbjct: 193 CKRQRQ 198
>gi|12644227|sp|P35452|HXD12_HUMAN Homeobox protein Hox-D12 (Hox-4H) Length = 275 Score = 69.7 bits (169), Expect = 1e-12 Identities = 33/63 (52%), Positives = 45/63 (71%), Gaps = 2/63 (3%) Query: 78 PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 PG+A KR YT Q+ ELE EF N ++ R +R E++N LNL+++Q+KIWFQNRRMK Sbjct: 204 PGEARKKRK--PYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMK 261 Query: 138 YKK 140 K+ Sbjct: 262 KKR 264
>gi|14194481|sp|Q9HBU1|BARX1_HUMAN Homeobox protein BarH-like 1 Length = 225 Score = 69.3 bits (168), Expect = 2e-12 Identities = 40/109 (36%), Positives = 61/109 (55%), Gaps = 10/109 (9%) Query: 55 PSSAGGHPKAHELSESCAGDKSPPGQASSK-----RARTAYTSAQLVELEKEFHFNRYLC 109 P +AG EL + + PG+ +K R+RT +T QL+ LEK F +YL Sbjct: 80 PGAAGAPHLPLELHVRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLS 139 Query: 110 RPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSR 158 P R+++A L L++ Q+K W+QNRRMK+KK +L G +SP++ Sbjct: 140 TPDRIDLAESLGLSQLQVKTWYQNRRMKWKKI-----VLQGGGLESPTK 183
>gi|20532295|sp|Q9UIW0|VAX2_HUMAN Ventral anterior homeobox 2 Length = 290 Score = 68.2 bits (165), Expect = 4e-12 Identities = 32/59 (54%), Positives = 41/59 (69%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 KR RT++T+ QL LE EF +Y+ R E+A LNL+E Q+K+WFQNRR K KKDQ Sbjct: 103 KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQ 161
>gi|21903415|sp|P19622|HME2_HUMAN Homeobox protein engrailed-2 (Hu-En-2) Length = 333 Score = 67.8 bits (164), Expect = 5e-12 Identities = 35/65 (53%), Positives = 41/65 (63%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 KR RTA+T+ QL L+ EF NRYL RR +A L+L E QIKIWFQN+R K KK Sbjct: 245 KRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATG 304 Query: 144 GKGML 148 K L Sbjct: 305 NKNTL 309
>gi|29336920|sp|Q9BZE3|BARH1_HUMAN BarH-like 1 homeobox protein (FKSG31 protein) Length = 327 Score = 67.4 bits (163), Expect = 7e-12 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 1/94 (1%) Query: 70 SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 129 S + D P ++ARTA+T QL +LE+ F +YL R+E+A LNLT+ Q+K Sbjct: 165 SSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKT 224 Query: 130 WFQNRRMKYKKDQK-GKGMLTSSGGQSPSRSPVP 162 W+QNRR K+K+ G +L +G S + P Sbjct: 225 WYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP 258
>gi|27923817|sp|Q9H2Z4|NK24_HUMAN Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D) Length = 353 Score = 67.4 bits (163), Expect = 7e-12 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Query: 81 ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 A ++ R ++ AQ+ ELE+ F +YL P R +A++++LT Q+KIWFQN R K K+ Sbjct: 187 APRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR 246 Query: 141 DQKGKG--MLTSSGGQSPSRSPVP 162 K K L GG P P P Sbjct: 247 QAKDKAAQQLQQEGGLGPPPPPPP 270
>gi|14917010|sp|Q05925|HME1_HUMAN Homeobox protein engrailed-1 (Hu-En-1) Length = 392 Score = 67.0 bits (162), Expect = 8e-12 Identities = 33/66 (50%), Positives = 41/66 (62%) Query: 75 KSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNR 134 K + KR RTA+T+ QL L+ EF NRY+ RR +A L+L E QIKIWFQN+ Sbjct: 295 KKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNK 354 Query: 135 RMKYKK 140 R K KK Sbjct: 355 RAKIKK 360
>gi|6016208|sp|O15522|NK28_HUMAN Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) Length = 239 Score = 67.0 bits (162), Expect = 8e-12 Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 10/113 (8%) Query: 31 QPYPASAALGADGEYHRPA--CSLQ-SPSSAGGHPKAHELSESCAGDKSPPGQASSKRAR 87 QP P +A L ++ ++ + SL+ SP + P A S +K K+ R Sbjct: 36 QPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKR-------KKRR 88 Query: 88 TAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ AQ +ELE+ F RYL P R ++A+LL LT Q+KIWFQN R K K+ Sbjct: 89 VLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141
>gi|3915680|sp|Q92988|DLX4_HUMAN Homeobox protein DLX-4 (DLX-7) (DLX-8) Length = 347 Score = 66.2 bits (160), Expect = 1e-11 Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK--D 141 ++ RT Y+S QL L + F +YL P R ++A L LT+ Q+KIWFQN+R KYKK Sbjct: 226 RKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK 285 Query: 142 QKGKGMLTSSGGQSPSRSPVPP 163 Q G G++ S SP P Sbjct: 286 QNSGGQEGDFPGRTFSVSPCSP 307
>gi|1174819|sp|P43699|TITF1_HUMAN Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A) Length = 371 Score = 65.9 bits (159), Expect = 2e-11 Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 12/121 (9%) Query: 26 YNANQQP-YPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSK 84 Y AN P +PA + + PA + S GG ++S++ A P A + Sbjct: 114 YGANPDPRFPAIS------RFMGPASGMNM-SGMGGLGSLGDVSKNMA----PLPSAPRR 162 Query: 85 RARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKG 144 + R ++ AQ+ ELE+ F +YL P R +A++++LT Q+KIWFQN R K K+ K Sbjct: 163 KRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKD 222 Query: 145 K 145 K Sbjct: 223 K 223
>gi|6093723|sp|O75364|PITX3_HUMAN Pituitary homeobox 3 (Homeobox protein PITX3) Length = 302 Score = 65.5 bits (158), Expect = 2e-11 Identities = 50/146 (34%), Positives = 68/146 (46%), Gaps = 24/146 (16%) Query: 41 ADGEYHRPACSLQSPSSAGGHP-------KAHELSESCAGDKSPPG--------QASSKR 85 ++ E PA SL + HP K E S+S S PG + +R Sbjct: 7 SEAEARSPALSLSDAGTP--HPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQRR 64 Query: 86 ARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKG- 144 RT +TS QL ELE F NRY R E+A NLTE ++++WF+NRR K++K ++ Sbjct: 65 QRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ 124 Query: 145 -----KGMLTSS-GGQSPSRSPVPPG 164 KG + GG P V PG Sbjct: 125 QAELCKGSFAAPLGGLVPPYEEVYPG 150
>gi|47117915|sp|Q9NY43|BARH2_HUMAN BarH-like 2 homeobox protein Length = 387 Score = 65.5 bits (158), Expect = 2e-11 Identities = 37/96 (38%), Positives = 56/96 (58%), Gaps = 2/96 (2%) Query: 69 ESCAGDKSPPGQASSKR-ARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQI 127 E + +SPP +A R ARTA++ QL +LE+ F +YL R+++A LNLT+ Q+ Sbjct: 217 EITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQV 276 Query: 128 KIWFQNRRMKYKKDQK-GKGMLTSSGGQSPSRSPVP 162 K W+QNRR K+K+ G +L +G S + P Sbjct: 277 KTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFP 312
>gi|6174907|sp|Q99697|PITX2_HUMAN Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1 responsive protein ARP1) Length = 317 Score = 65.1 bits (157), Expect = 3e-11 Identities = 37/102 (36%), Positives = 54/102 (52%), Gaps = 6/102 (5%) Query: 61 HPKAHELSESCAGD------KSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRV 114 HP A+E +S G + P + +R RT +TS QL ELE F NRY R Sbjct: 57 HPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTRE 116 Query: 115 EMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSP 156 E+A NLTE ++++WF+NRR K++K ++ + G P Sbjct: 117 EIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGP 158
>gi|57015304|sp|Q04741|EMX1_HUMAN Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Length = 257 Score = 65.1 bits (157), Expect = 3e-11 Identities = 29/65 (44%), Positives = 43/65 (66%) Query: 78 PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 P KR RTA++ +QL+ LE+ F N Y+ R ++A L+L+E Q+K+WFQNRR K Sbjct: 154 PFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTK 213 Query: 138 YKKDQ 142 YK+ + Sbjct: 214 YKRQK 218
>gi|50403792|sp|Q92826|HXB13_HUMAN Homeobox protein Hox-B13 Length = 284 Score = 64.7 bits (156), Expect = 4e-11 Identities = 48/154 (31%), Positives = 70/154 (45%), Gaps = 32/154 (20%) Query: 11 AIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHR----PACSLQSPSSAGGHPKAHE 66 A Y GYP + A+ LGA GE P S QS + AGG Sbjct: 128 AFYPGYP----GTYQPMASYLDVSVVQTLGAPGEPRHDSLLPVDSYQSWALAGGWNS--- 180 Query: 67 LSESCAGDKSPPGQ--------------------ASSKRARTAYTSAQLVELEKEFHFNR 106 C G+++PPG ++ R Y+ QL ELE+E+ N+ Sbjct: 181 -QMCCQGEQNPPGPFWKAAFADSSGQHPPDACAFRRGRKKRIPYSKGQLRELEREYAANK 239 Query: 107 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ + +R +++ +L+ERQI IWFQNRR+K KK Sbjct: 240 FITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273
>gi|13959687|sp|P35548|MSX2_HUMAN Homeobox protein MSX-2 (Hox-8) Length = 267 Score = 64.7 bits (156), Expect = 4e-11 Identities = 33/84 (39%), Positives = 51/84 (60%), Gaps = 4/84 (4%) Query: 62 PKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLN 121 P H +C K ++++ RT +T++QL+ LE++F +YL R E ++ LN Sbjct: 125 PPRHTSPTTCTLRK----HKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLN 180 Query: 122 LTERQIKIWFQNRRMKYKKDQKGK 145 LTE Q+KIWFQNRR K K+ Q+ + Sbjct: 181 LTETQVKIWFQNRRAKAKRLQEAE 204
>gi|399982|sp|P31314|TLX1_HUMAN T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (TCL-3 proto-oncogene) Length = 330 Score = 64.3 bits (155), Expect = 6e-11 Identities = 28/67 (41%), Positives = 43/67 (64%), Gaps = 3/67 (4%) Query: 74 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 +++PP K+ RT++T Q+ ELEK FH +YL R +A L +T+ Q+K WFQN Sbjct: 195 NRTPP---KKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQN 251 Query: 134 RRMKYKK 140 RR K+++ Sbjct: 252 RRTKWRR 258
>gi|19862512|sp|Q04743|EMX2_HUMAN Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2) Length = 252 Score = 63.9 bits (154), Expect = 7e-11 Identities = 28/59 (47%), Positives = 42/59 (71%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 KR RTA++ +QL+ LE F N Y+ R ++A+ L+LTE Q+K+WFQNRR K+K+ + Sbjct: 155 KRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQK 213
>gi|23503066|sp|P28360|MSX1_HUMAN Homeobox protein MSX-1 (Hox-7) Length = 297 Score = 63.9 bits (154), Expect = 7e-11 Identities = 32/75 (42%), Positives = 49/75 (65%), Gaps = 5/75 (6%) Query: 76 SPPG-----QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIW 130 SPP ++++ RT +T+AQL+ LE++F +YL R E ++ L+LTE Q+KIW Sbjct: 154 SPPACTLRKHKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIW 213 Query: 131 FQNRRMKYKKDQKGK 145 FQNRR K K+ Q+ + Sbjct: 214 FQNRRAKAKRLQEAE 228
>gi|12644330|sp|P56179|DLX6_HUMAN Homeobox protein DLX-6 Length = 175 Score = 62.8 bits (151), Expect = 2e-10 Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 6/86 (6%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK--- 140 ++ RT Y+S QL L F +YL P R E+A L LT+ Q+KIWFQN+R K+KK Sbjct: 50 RKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLK 109 Query: 141 ---DQKGKGMLTSSGGQSPSRSPVPP 163 + L S SP +PP Sbjct: 110 QGSNPHESDPLQGSAALSPRSPALPP 135
>gi|2828197|sp|P31271|HXA13_HUMAN Homeobox protein Hox-A13 (Hox-1J) Length = 388 Score = 62.8 bits (151), Expect = 2e-10 Identities = 31/69 (44%), Positives = 45/69 (65%), Gaps = 4/69 (5%) Query: 76 SPPGQASS----KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWF 131 S P ASS ++ R YT QL ELE+E+ N+++ + +R ++ NL+ERQ+ IWF Sbjct: 311 SHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWF 370 Query: 132 QNRRMKYKK 140 QNRR+K KK Sbjct: 371 QNRRVKEKK 379
>gi|23831508|sp|O43711|TLX3_HUMAN T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2) Length = 291 Score = 62.8 bits (151), Expect = 2e-10 Identities = 31/85 (36%), Positives = 50/85 (58%), Gaps = 6/85 (7%) Query: 74 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 +++PP + K+ RT+++ Q+ ELEK FH +YL R +A L +T+ Q+K WFQN Sbjct: 160 NRTPPKR---KKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQN 216 Query: 134 RRMKYKKDQKGKGMLTSSGGQSPSR 158 RR K+++ + + GQ SR Sbjct: 217 RRTKWRRQTAEE---READGQQASR 238
>gi|6016211|sp|P78426|NK61_HUMAN Homeobox protein Nkx-6.1 Length = 367 Score = 62.4 bits (150), Expect = 2e-10 Identities = 39/119 (32%), Positives = 53/119 (44%), Gaps = 16/119 (13%) Query: 34 PASAALGADGEYHRPACSL------------QSPSSAGGHPKAHELSESCAGDKSPPGQA 81 P++AA+ A G Y +P L QSP S DK Sbjct: 179 PSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKD----G 234 Query: 82 SSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 K R ++ Q+ LEK F +YL P R +A L +TE Q+K+WFQNRR K++K Sbjct: 235 KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 293
>gi|8134640|sp|O14813|PHX2A_HUMAN Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein) Length = 284 Score = 61.6 bits (148), Expect = 4e-10 Identities = 51/159 (32%), Positives = 76/159 (47%), Gaps = 22/159 (13%) Query: 1 MQKATYYDSSAIY--GGYPYQAANGFAYNANQQPYPA----SAALGADGEYHRPACSLQS 54 M+ + Y D A GG+ Y A+ A P PA + ALGA + H+PA Sbjct: 16 MEASAYGDFGACSQPGGFQYSPLRP-AFPAAGPPCPALGSSNCALGALRD-HQPAPYSAV 73 Query: 55 PSSAGGHPKA-HELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRR 113 P + P HE + +R RT +TSAQL ELE+ F Y R Sbjct: 74 PYNFFPEPSGLHE-------------KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTR 120 Query: 114 VEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSG 152 E+A ++LTE ++++WFQNRR K++K ++ ++G Sbjct: 121 EELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAG 159
>gi|27923733|sp|Q96QS3|ARX_HUMAN Homeobox protein ARX (Aristaless-related homeobox) Length = 562 Score = 60.5 bits (145), Expect = 8e-10 Identities = 50/145 (34%), Positives = 70/145 (48%), Gaps = 17/145 (11%) Query: 35 ASAALGADGEYHRPACSLQ-SPSSAGGHPKAHELSESCAGDKSPPG--QASSKRARTAYT 91 A+AA+ +G P L P A G + S AG S G + +R RT +T Sbjct: 278 AAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLS-AGSDSEEGLLKRKQRRYRTTFT 336 Query: 92 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKG------- 144 S QL ELE+ F Y R E+A L+LTE ++++WFQNRR K++K +K Sbjct: 337 SYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPP 396 Query: 145 ----KGMLTSSGGQSP--SRSPVPP 163 G L+++ SP SP PP Sbjct: 397 GLPFPGPLSATHPLSPYLDASPFPP 421
>gi|547658|sp|Q03014|HHEX_HUMAN Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX) Length = 270 Score = 60.1 bits (144), Expect = 1e-09 Identities = 25/57 (43%), Positives = 39/57 (68%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 K + +++ Q +ELEK+F +YL P R +A +L L+ERQ+K WFQNRR K+++ Sbjct: 138 KGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR 194
>gi|2833256|sp|Q14774|HLX1_HUMAN Homeobox protein HLX1 (Homeobox protein HB24) Length = 488 Score = 60.1 bits (144), Expect = 1e-09 Identities = 27/74 (36%), Positives = 46/74 (62%), Gaps = 2/74 (2%) Query: 86 ARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK--KDQK 143 +R +++ Q LEK F +Y+ +P R ++A +L LT+ Q+K+WFQNRRMK++ K+ + Sbjct: 279 SRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQ 338 Query: 144 GKGMLTSSGGQSPS 157 + G+ PS Sbjct: 339 AQKDKDKEAGEKPS 352
>gi|20141539|sp|P31276|HXC13_HUMAN Homeobox protein Hox-C13 (Hox-3G) Length = 330 Score = 59.7 bits (143), Expect = 1e-09 Identities = 26/57 (45%), Positives = 40/57 (70%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ R YT QL ELEKE+ ++++ + +R ++ NL+ERQ+ IWFQNRR+K KK Sbjct: 261 RKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317
>gi|20532396|sp|O43763|TLX2_HUMAN T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein) Length = 284 Score = 59.7 bits (143), Expect = 1e-09 Identities = 47/174 (27%), Positives = 74/174 (42%), Gaps = 46/174 (26%) Query: 8 DSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACS-LQSPSSAGGHPKAHE 66 ++ A GGY A+G+ + P P S+ +G G PA L P AGG P Sbjct: 46 ENGAFSGGY--HGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPG 103 Query: 67 LSE-----SCAG-----------------------------------DKSPPGQASSKRA 86 S AG +++PP + K+ Sbjct: 104 PSGLGGAGGLAGLTFPWMDSGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKR---KKP 160 Query: 87 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 RT+++ +Q++ELE+ F +YL R +A L +T+ Q+K WFQNRR K+++ Sbjct: 161 RTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRR 214
>gi|48428084|sp|Q8N693|ESX1L_HUMAN Extraembryonic, spermatogenesis, homeobox 1-like protein Length = 406 Score = 59.3 bits (142), Expect = 2e-09 Identities = 33/91 (36%), Positives = 53/91 (58%), Gaps = 3/91 (3%) Query: 53 QSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPR 112 + P + P+ E ++ G + P + +R RTA+T QL ELE F ++Y Sbjct: 112 EPPQTTVEGPQPAEGPQTAEGPQPPERK---RRRRTAFTQFQLQELENFFDESQYPDVVA 168 Query: 113 RVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 R +A LNLTE ++++WFQNRR K+K++Q+ Sbjct: 169 RERLAARLNLTEDRVQVWFQNRRAKWKRNQR 199
>gi|17380297|sp|Q9Y2V3|RX_HUMAN Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein) Length = 346 Score = 59.3 bits (142), Expect = 2e-09 Identities = 46/148 (31%), Positives = 70/148 (47%), Gaps = 15/148 (10%) Query: 34 PASAALGADGEYHRPACSLQ--SPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYT 91 P + A + E RP C + + G P E+ ++ P + +R RT +T Sbjct: 86 PPAPAPAPEYEAPRPYCPKEPWEARPSPGLPVGPATGEAKLSEEEQP-KKKHRRNRTTFT 144 Query: 92 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK---GKGML 148 + QL ELE+ F + Y R E+A +NL E ++++WFQNRR K+++ +K L Sbjct: 145 TYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKL 204 Query: 149 TSSGGQSPSRSP---------VPPGAGG 167 S S SRSP PG+GG Sbjct: 205 QDSPLLSFSRSPPSATLSPLGAGPGSGG 232
>gi|2851475|sp|P35453|HXD13_HUMAN Homeobox protein Hox-D13 (Hox-4I) Length = 335 Score = 58.9 bits (141), Expect = 2e-09 Identities = 26/57 (45%), Positives = 39/57 (68%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ R YT QL ELE E+ N+++ + +R ++ NL+ERQ+ IWFQNRR+K KK Sbjct: 269 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325
>gi|8247951|sp|P23759|PAX7_HUMAN Paired box protein Pax-7 (HUP1) Length = 520 Score = 58.5 bits (140), Expect = 3e-09 Identities = 37/108 (34%), Positives = 54/108 (50%), Gaps = 8/108 (7%) Query: 63 KAHELSESCAGDKSP--PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLL 120 K + L E + P P + +R+RT +T+ QL ELEK F Y R E+A Sbjct: 195 KGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRT 254 Query: 121 NLTERQIKIWFQNRRMKYKKDQKGKGMLTS-----SGGQSPSRSPVPP 163 LTE ++++WF NRR +++K Q G L + GG P+ P P Sbjct: 255 KLTEARVQVWFSNRRARWRK-QAGANQLAAFNHLLPGGFPPTGMPTLP 301
>gi|3023579|sp|Q15699|CRT1_HUMAN Cartilage homeoprotein 1 (CART-1) Length = 326 Score = 58.5 bits (140), Expect = 3e-09 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Query: 50 CSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSK--RARTAYTSAQLVELEKEFHFNRY 107 C+ S G + EL E GDK +SSK R RT +TS QL ELEK F Y Sbjct: 99 CNSLRMSPVKGMQEKGELDE--LGDKCDTNVSSSKKRRHRTTFTSLQLEELEKVFQKTHY 156 Query: 108 LCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 R ++A LTE ++++WFQNRR K++K ++ Sbjct: 157 PDVYVREQLALRTELTEARVQVWFQNRRAKWRKRER 192
>gi|8134644|sp|Q99453|PHX2B_HUMAN Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox) Length = 314 Score = 58.2 bits (139), Expect = 4e-09 Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 21 ANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQ 80 A+GF YN + + A++ + +CSL + P A + + Sbjct: 39 ASGFQYNPIRTTFGATSGCPS---LTPGSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEK 95 Query: 81 ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 +R RT +TSAQL ELE+ F Y R E+A ++LTE ++++WFQNRR K++K Sbjct: 96 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 155 Query: 141 DQK 143 ++ Sbjct: 156 QER 158
>gi|12644475|sp|Q99811|PRRX2_HUMAN Paired mesoderm homeobox protein 2 (PRX-2) (Paired related homeobox protein 2) Length = 253 Score = 57.8 bits (138), Expect = 5e-09 Identities = 37/133 (27%), Positives = 62/133 (46%), Gaps = 16/133 (12%) Query: 47 RPACSLQSPSSAGGHPKAHELSESCA---GDKSPPGQASS-------KRARTAYTSAQLV 96 RP ++ A P A G+ PG+ S+ +R RT + S+QL Sbjct: 58 RPGARAEAREGAAREPSGGSSGSEAAPQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQ 117 Query: 97 ELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ------KGKGMLTS 150 LE+ F Y R E+A +NL+E ++++WFQNRR K+++++ + +L S Sbjct: 118 ALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKS 177 Query: 151 SGGQSPSRSPVPP 163 ++ PV P Sbjct: 178 YSQEAAIEQPVAP 190
>gi|1730095|sp|P52954|LBX1_HUMAN Transcription factor LBX1 Length = 280 Score = 57.4 bits (137), Expect = 7e-09 Identities = 26/58 (44%), Positives = 39/58 (67%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 +++RTA+T+ Q+ ELEK F + +YL R ++A L LT Q+ WFQNRR K K++ Sbjct: 125 RKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRE 182
>gi|13626112|sp|Q9H161|ALX4_HUMAN Homeobox protein aristaless-like 4 Length = 411 Score = 56.6 bits (135), Expect = 1e-08 Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 5/111 (4%) Query: 34 PASAALGADGEYHRPACSLQSPSSAGGHPKAH-ELSESCAGDKSPPGQASSKRARTAYTS 92 P S +G D Y S++ G +A +L S + +R RT +TS Sbjct: 168 PDSDTVGMDSSY----LSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTS 223 Query: 93 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 QL ELEK F Y R ++A +LTE ++++WFQNRR K++K ++ Sbjct: 224 YQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 274
>gi|1172022|sp|P23760|PAX3_HUMAN Paired box protein Pax-3 (HUP2) Length = 479 Score = 55.5 bits (132), Expect = 3e-08 Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 6/91 (6%) Query: 78 PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 P + +R+RT +T+ QL ELE+ F Y R E+A LTE ++++WF NRR + Sbjct: 214 PLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRAR 273 Query: 138 YKKDQKGKGMLTS-----SGGQSPSRSPVPP 163 ++K Q G L + GG P+ P P Sbjct: 274 WRK-QAGANQLMAFNHLIPGGFPPTAMPTLP 303
>gi|6174916|sp|P54821|PRRX1_HUMAN Paired mesoderm homeobox protein 1 (PRX-1) (Paired related homeobox protein 1) (Homeobox protein PHOX1) Length = 245 Score = 55.1 bits (131), Expect = 3e-08 Identities = 34/119 (28%), Positives = 60/119 (50%), Gaps = 9/119 (7%) Query: 52 LQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRP 111 L+SP G + ++ ++ + +R RT + S+QL LE+ F Y Sbjct: 65 LESPGLTSGSDTPQQDNDQLNSEEKK--KRKQRRNRTTFNSSQLQALERVFERTHYPDAF 122 Query: 112 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQ------KGKGMLTS-SGGQSPSRSPVPP 163 R ++A +NLTE ++++WFQNRR K+++++ K +L S SG + P+ P Sbjct: 123 VREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVP 181
>gi|18202099|sp|O60902|SHOX2_HUMAN Short stature homeobox protein 2 (Paired-related homeobox protein SHOT) (Homeobox protein Og12X) Length = 331 Score = 53.1 bits (126), Expect = 1e-07 Identities = 37/105 (35%), Positives = 54/105 (51%), Gaps = 5/105 (4%) Query: 54 SPSSAGGHPKAHELSESCAGDKSPPGQASSK--RARTAYTSAQLVELEKEFHFNRYLCRP 111 SP P+ + E G + GQ K R+RT +T QL ELE+ F Y Sbjct: 110 SPRLTEVSPELKDRKEDAKGMEDE-GQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAF 168 Query: 112 RRVEMANLLNLTERQIKIWFQNRRMKYKK--DQKGKGMLTSSGGQ 154 R E++ L L+E ++++WFQNRR K +K +Q KG+L + Q Sbjct: 169 MREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQ 213
>gi|3287764|sp|O43186|CRX_HUMAN Cone-rod homeobox protein Length = 299 Score = 52.4 bits (124), Expect = 2e-07 Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 P +R RT +T +QL ELE F +Y R E+A +NL E ++++WF+NRR Sbjct: 33 PSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRA 92 Query: 137 KYKKD-QKGKGMLTSSGGQSPSR 158 K ++ Q+ K GGQ+ +R Sbjct: 93 KCRQQRQQQKQQQQPPGGQAKAR 115
>gi|12230168|sp|Q9UBX0|HESX1_HUMAN Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf) Length = 185 Score = 52.0 bits (123), Expect = 3e-07 Identities = 27/60 (45%), Positives = 36/60 (60%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 +R RTA+T Q+ LE F N Y R ++A LNL E +I+IWFQNRR K K+ + Sbjct: 109 RRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHR 168
>gi|25009572|sp|Q9NZR4|VSX1_HUMAN Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX) Length = 365 Score = 52.0 bits (123), Expect = 3e-07 Identities = 36/101 (35%), Positives = 49/101 (48%), Gaps = 2/101 (1%) Query: 48 PACSLQSPSSAGGHPKAHELSESCAGDKSPP--GQASSKRARTAYTSAQLVELEKEFHFN 105 PA Q S + SE K+ P G+ +R RT +T+ QL ELEK F Sbjct: 127 PALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEA 186 Query: 106 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKG 146 Y R +A L E +I++WFQNRR K++K +K G Sbjct: 187 HYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWG 227
>gi|13626107|sp|O95076|ALX3_HUMAN Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3) Length = 343 Score = 52.0 bits (123), Expect = 3e-07 Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 10/93 (10%) Query: 51 SLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCR 110 SL P S G P + EL+++ ++ +R RT +++ QL ELEK F Y Sbjct: 131 SLHLPLSPG-LPDSMELAKN---------KSKKRRNRTTFSTFQLEELEKVFQKTHYPDV 180 Query: 111 PRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 R ++A +LTE ++++WFQNRR K++K ++ Sbjct: 181 YAREQLALRTDLTEARVQVWFQNRRAKWRKRER 213
>gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN Zinc finger homeobox protein 2 Length = 1427 Score = 52.0 bits (123), Expect = 3e-07 Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 1/98 (1%) Query: 56 SSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVE 115 S AGGH E ES G+ P A + +RT +T Q L+ F + Y Sbjct: 424 SRAGGHWPIEE-EESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVER 482 Query: 116 MANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGG 153 +A+LL L R + +WFQN R K +K+ G + + GG Sbjct: 483 LASLLGLASRVVVVWFQNARQKARKNACEGGSMPTGGG 520
Score = 40.4 bits (93), Expect = 9e-04 Identities = 35/124 (28%), Positives = 49/124 (39%), Gaps = 4/124 (3%) Query: 32 PYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYT 91 P + +L A A SL P S G A S G P +R RT + Sbjct: 873 PESEACSLSAGDLSDSSASSLAEPESPG----AGGTSGGPGGGTGVPDGMGQRRYRTQMS 928 Query: 92 SAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSS 151 S QL ++ + R + + L +R I++WFQN R K KK + S+ Sbjct: 929 SLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQGTAAGST 988 Query: 152 GGQS 155 GG S Sbjct: 989 GGSS 992
Score = 34.3 bits (77), Expect = 0.061 Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%) Query: 73 GDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQ 132 G+ PP KR RT QL L + + + R ++ + L +R +++WFQ Sbjct: 705 GEGEPP---RDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ 761 Query: 133 NRRMKYKKDQKGKGMLTSSGGQSPSRSPVPP 163 N R + + KG S+ G PS + PP Sbjct: 762 NTRARER-----KGQFRSTPGGVPSPAVKPP 787
>gi|6685480|sp|O15499|GSCL_HUMAN Homeobox protein goosecoid-like (GSC-2) Length = 205 Score = 51.6 bits (122), Expect = 4e-07 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 10/115 (8%) Query: 32 PYPASAALGADGEYHR---PACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRART 88 P A+A LGA + PA L + AGG S + G P Q ++R RT Sbjct: 79 PPEAAAGLGARLAWPLRLGPAVPLSLGAPAGG-------SGALPGAVGPGSQRRTRRHRT 131 Query: 89 AYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 ++ QL LE F N+Y R +A + L E ++++WF+NRR K++ ++ Sbjct: 132 IFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186
>gi|51702790|sp|P63015|PAX6_MOUSE Paired box protein Pax-6 (Oculorhombin) gi|6174889|sp|P26367|PAX6_HUMAN Paired box protein Pax-6 (Oculorhombin) (Aniridia, type II protein) Length = 422 Score = 51.2 bits (121), Expect = 5e-07 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 +R RT++T Q+ LEKEF Y R +A ++L E +I++WF NRR K+++++K Sbjct: 211 QRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK 270 Query: 144 GKGMLTSSGGQSPSRSPV 161 + +PS P+ Sbjct: 271 LRNQ-RRQASNTPSHIPI 287
>gi|6831676|sp|O15266|SHOX_HUMAN Short stature homeobox protein (Short stature homeobox containing protein) (Pseudoautosomal homeobox containing osteogenic protein) Length = 292 Score = 50.8 bits (120), Expect = 6e-07 Identities = 28/77 (36%), Positives = 45/77 (58%), Gaps = 2/77 (2%) Query: 74 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 D+ + +R+RT +T QL ELE+ F Y R E++ L L+E ++++WFQN Sbjct: 108 DEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQN 167 Query: 134 RRMKYKK--DQKGKGML 148 RR K +K +Q KG++ Sbjct: 168 RRAKCRKQENQMHKGVI 184
>gi|417425|sp|P32242|OTX1_HUMAN Homeobox protein OTX1 Length = 354 Score = 50.8 bits (120), Expect = 6e-07 Identities = 32/90 (35%), Positives = 46/90 (51%), Gaps = 1/90 (1%) Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 P +R RT +T +QL LE F RY R E+A +NL E ++++WF+NRR Sbjct: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91 Query: 137 KYKKDQKGKGMLTSSGGQSPSRSPVPPGAG 166 K ++ Q+ G T S SPV +G Sbjct: 92 KCRQQQQ-SGSGTKSRPAKKKSSPVRESSG 120
>gi|3914276|sp|O43316|PAX4_HUMAN Paired box protein Pax-4 Length = 350 Score = 50.4 bits (119), Expect = 8e-07 Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 3/96 (3%) Query: 72 AGDKSPPGQ--ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 129 +G ++P G + R RT ++ +Q LEKEF +Y R ++A +L E +++ Sbjct: 157 SGSETPRGTHPGTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRV 216 Query: 130 WFQNRRMKYKKDQKGKGMLTSSGGQSPSRSP-VPPG 164 WF NRR K+++ +K K + G P V PG Sbjct: 217 WFSNRRAKWRRQEKLKWEMQLPGASQGLTVPRVAPG 252
>gi|417427|sp|P32243|OTX2_HUMAN Homeobox protein OTX2 Length = 289 Score = 50.1 bits (118), Expect = 1e-06 Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 4/82 (4%) Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 P +R RT +T AQL LE F RY R E+A +NL E ++++WF+NRR Sbjct: 32 PATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91 Query: 137 KYKKDQKGKGMLTSSGGQSPSR 158 K ++ Q+ + +GGQ+ R Sbjct: 92 KCRQQQQQQ----QNGGQNKVR 109
>gi|17374365|sp|P58304|CHX10_HUMAN Homeobox protein CHX10 (Ceh-10 homeodomain containing homolog) Length = 361 Score = 50.1 bits (118), Expect = 1e-06 Identities = 27/60 (45%), Positives = 37/60 (61%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 +R RT +TS QL ELEK F+ Y R +A L E +I++WFQNRR K++K +K Sbjct: 149 RRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208
>gi|37537960|sp|Q8NHV9|PEPP1_HUMAN Paired-like homeobox protein PEPP-1 (Ovary-, testis- and epididymis-expressed gene protein) Length = 184 Score = 49.3 bits (116), Expect = 2e-06 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 7/96 (7%) Query: 55 PSSAGGHPKAHELSE-------SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRY 107 P GG+ + + + A + P + RT +T Q+ ELE F +Y Sbjct: 68 PEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQY 127 Query: 108 LCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 P R E+A L +TE ++++WF+N+R + ++ Q+ Sbjct: 128 PDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQR 163
>gi|18202510|sp|Q15911|ATBF1_HUMAN Alpha-fetoprotein enhancer binding protein (AT motif-binding factor) (AT-binding transcription factor 1) Length = 3703 Score = 49.3 bits (116), Expect = 2e-06 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 3/73 (4%) Query: 77 PPGQ---ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 PP Q S + +RT +T QL L+ F N Y +++NLLNL R I +WFQN Sbjct: 2233 PPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQN 2292 Query: 134 RRMKYKKDQKGKG 146 R K +K+ + +G Sbjct: 2293 ARQKARKNYENQG 2305
Score = 40.4 bits (93), Expect = 9e-04 Identities = 30/89 (33%), Positives = 46/89 (51%), Gaps = 10/89 (11%) Query: 54 SPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRR 113 SP ++G K+ + +GD+ PGQ KR RT T+ QL L+ F+ R Sbjct: 2927 SPGASGSAGKSGD-----SGDR--PGQ---KRFRTQMTNLQLKVLKSCFNDYRTPTMLEC 2976 Query: 114 VEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 + N + L +R +++WFQN R K KK + Sbjct: 2977 EVLGNDIGLPKRVVQVWFQNARAKEKKSK 3005
Score = 37.0 bits (84), Expect = 0.009 Identities = 22/64 (34%), Positives = 31/64 (48%) Query: 80 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 139 Q +KR RT T QL L + F N + EMA+ L ++ IK WF+N K + Sbjct: 2142 QQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKER 2201 Query: 140 KDQK 143 + K Sbjct: 2202 QRNK 2205
Score = 36.6 bits (83), Expect = 0.012 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 9/104 (8%) Query: 48 PACSLQSPSSAGG-----HPKAHELSESCAG--DKSPPGQASS--KRARTAYTSAQLVEL 98 PA S SPS+ K E + + G D G+ KR RT T QL L Sbjct: 2597 PASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEIL 2656 Query: 99 EKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 +++ + R +A+ + L +R +++WFQN R + +K Q Sbjct: 2657 YQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERKGQ 2700
>gi|6093787|sp|O75360|PROP1_HUMAN Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary specific homeodomain factor) Length = 226 Score = 48.9 bits (115), Expect = 2e-06 Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 7/111 (6%) Query: 33 YPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTS 92 +PA+ + P C + P + GG + G + P S +R RT ++ Sbjct: 26 HPATGTPTTTVDSSAPPCR-RLPGAGGGRSRFSPQG----GQRGRPH--SRRRHRTTFSP 78 Query: 93 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 QL +LE F N+Y R +A L+E +I++WFQNRR K +K ++ Sbjct: 79 VQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER 129
>gi|37537987|sp|Q9BQY4|PEP2_HUMAN Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1) Length = 288 Score = 47.8 bits (112), Expect = 5e-06 Identities = 24/66 (36%), Positives = 38/66 (57%), Gaps = 1/66 (1%) Query: 78 PGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 PG A A+T QL ELE+ F ++ R +A +N+TE ++IWF+NRR K Sbjct: 130 PGNAQQPNVH-AFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAK 188 Query: 138 YKKDQK 143 +++ Q+ Sbjct: 189 WRRHQR 194
>gi|12643415|sp|Q9UBR4|LHX3_HUMAN LIM/homeobox protein Lhx3 Length = 397 Score = 47.8 bits (112), Expect = 5e-06 Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 10/100 (10%) Query: 75 KSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNR 134 K +A++KR RT T+ QL L+ ++ + R R ++++ L R +++WFQNR Sbjct: 149 KQREAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNR 208 Query: 135 RMKYKKDQKGKG----------MLTSSGGQSPSRSPVPPG 164 R K K+ +K G M S GG + V G Sbjct: 209 RAKEKRLKKDAGRQRWGQYFRNMKRSRGGSKSDKDSVQEG 248
>gi|7531125|sp|P56915|GSC_HUMAN Homeobox protein goosecoid Length = 252 Score = 46.6 bits (109), Expect = 1e-05 Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 9/84 (10%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 143 +R RT +T QL LE F +Y R ++A ++L E ++++WF+NRR K+++ ++ Sbjct: 156 RRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKR 215 Query: 144 G---------KGMLTSSGGQSPSR 158 K TSS SP + Sbjct: 216 SSSEESENAEKWNKTSSSKASPEK 239
>gi|47117871|sp|P78411|IRX5_HUMAN Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A) Length = 482 Score = 44.7 bits (104), Expect = 5e-05 Identities = 42/140 (30%), Positives = 59/140 (42%), Gaps = 23/140 (16%) Query: 17 PYQAANGFA-----YNANQQ--PYPASAALGADGEY------HRPACSLQSPSSAGGHPK 63 PY + F YN++ Q PA+AA A Y H P + S G HP Sbjct: 47 PYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMA----GSLGYHPY 102 Query: 64 AHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLT 123 A L GD P + ++ R TA A L E K N Y + ++ +A + +T Sbjct: 103 AAPLGSYPYGD--PAYRKNATRDATATLKAWLNEHRK----NPYPTKGEKIMLAIITKMT 156 Query: 124 ERQIKIWFQNRRMKYKKDQK 143 Q+ WF N R + KK+ K Sbjct: 157 LTQVSTWFANARRRLKKENK 176
>gi|8134548|sp|Q9UPM6|LHX61_HUMAN LIM/homeobox protein Lhx6.1 (Lhx6) Length = 363 Score = 44.7 bits (104), Expect = 5e-05 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%) Query: 83 SKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQ 142 +KRART++T+ QL ++ +F + ++A++ L+ R I++WFQN R ++KK Sbjct: 219 AKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHT 278 Query: 143 KGKGMLTSSGGQSPSRSP 160 + S G PSR P Sbjct: 279 PQHPVPPS--GAPPSRLP 294
>gi|12643346|sp|Q9NQ69|LHX9_HUMAN LIM/homeobox protein Lhx9 Length = 388 Score = 44.3 bits (103), Expect = 6e-05 Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 6/91 (6%) Query: 77 PPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRM 136 PP Q +KR RT++ QL ++ F N ++A LT+R +++WFQN R Sbjct: 253 PPSQ-KTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARA 311 Query: 137 KYKKD--QKGKGMLTSSGGQSPSRSPVPPGA 165 K++++ ++ G + + G S P PP A Sbjct: 312 KFRRNLLRQENGGVDKADGTS---LPAPPSA 339
>gi|20138668|sp|Q969G2|LHX4_HUMAN LIM/homeobox protein Lhx4 Length = 367 Score = 43.9 bits (102), Expect = 8e-05 Identities = 23/67 (34%), Positives = 38/67 (56%) Query: 80 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 139 +A +KR RT T+ QL L+ + + R R ++++ L R +++WFQNRR K K Sbjct: 131 EAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEK 190 Query: 140 KDQKGKG 146 + +K G Sbjct: 191 RLKKDAG 197
>gi|8247936|sp|P50458|LHX2_HUMAN LIM/homeobox protein Lhx2 (Homeobox protein LH-2) Length = 406 Score = 43.5 bits (101), Expect = 1e-04 Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 3/95 (3%) Query: 74 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 133 D+ P +KR RT++ QL ++ F N ++A LT+R +++WFQN Sbjct: 257 DQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQN 316 Query: 134 RRMKYKKD---QKGKGMLTSSGGQSPSRSPVPPGA 165 R K++++ Q+ G+ S+ + +P P + Sbjct: 317 ARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPAS 351
>gi|47117874|sp|P78415|IRX3_HUMAN Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1) Length = 501 Score = 43.1 bits (100), Expect = 1e-04 Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 21/146 (14%) Query: 10 SAIYGGYPYQAANGFA----YNANQQPY----PASAALGADGEYHRPACSLQSPSSAGG- 60 S++YG PY AA A Y A PY P LGA E + + +Q P++A Sbjct: 54 SSVYGA-PYAAAAAAAAAQGYGAFL-PYAAELPIFPQLGAQYEL-KDSPGVQHPAAAAAF 110 Query: 61 ---HPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMA 117 HP + + GD S P A+ R T+ A L E K N Y + ++ +A Sbjct: 111 PHPHPAFYPYGQYQFGDPSRPKNAT--RESTSTLKAWLNEHRK----NPYPTKGEKIMLA 164 Query: 118 NLLNLTERQIKIWFQNRRMKYKKDQK 143 + +T Q+ WF N R + KK+ K Sbjct: 165 IITKMTLTQVSTWFANARRRLKKENK 190
>gi|27923801|sp|Q8TE12|LMX1A_HUMAN LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1) Length = 382 Score = 43.1 bits (100), Expect = 1e-04 Identities = 32/106 (30%), Positives = 46/106 (43%), Gaps = 7/106 (6%) Query: 42 DGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASS-------KRARTAYTSAQ 94 D E R SL SP+++ E S + + G A KR RT T+ Q Sbjct: 147 DYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQ 206 Query: 95 LVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 + F + CR R +A L+ R +++WFQN+R K KK Sbjct: 207 RRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252
>gi|1352729|sp|P40425|PBX2_HUMAN Pre-B-cell leukemia transcription factor-2 (Homeobox protein PBX2) (G17 protein) Length = 430 Score = 42.0 bits (97), Expect = 3e-04 Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 20/98 (20%) Query: 92 SAQLVELEKEFHF----NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK-- 145 S Q E+ E+ + N Y + E+A +T Q+ WF N+R++YKK+ GK Sbjct: 252 SKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKN-IGKFQ 310 Query: 146 ----------GMLTSSGGQSPSRSPVPP---GAGGYLN 170 + + GG S + SP PP G+GG N Sbjct: 311 EEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFN 348
>gi|123402|sp|P09086|PO2F2_HUMAN POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer binding protein NF-A2) Length = 479 Score = 40.4 bits (93), Expect = 9e-04 Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 6/112 (5%) Query: 62 PKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLN 121 P ++LS G PG+ KR T+ + LEK F N+ + +A L+ Sbjct: 278 PSPNQLSSPSLGFDGLPGRRRKKR--TSIETNVRFALEKSFLANQKPTSEEILLIAEQLH 335 Query: 122 LTERQIKIWFQNRRMKYKK-DQKGKGMLTSSGGQSPSRSP---VPPGAGGYL 169 + + I++WF NRR K K+ + + S G+ S SP P G G L Sbjct: 336 MEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTL 387
>gi|20978495|sp|Q96A47|ISL2_HUMAN Insulin gene enhancer protein ISL-2 (Islet-2) Length = 359 Score = 40.4 bits (93), Expect = 9e-04 Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Query: 54 SPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTS-AQLVELEKEFHFNR--YLCR 110 SP S G P A L AG P +T T+ + V EK+ H R Y Sbjct: 154 SPRSPGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAAN 213 Query: 111 PR-----RVEMANLLNLTERQIKIWFQNRRMKYKK 140 PR + ++ + L+ R I++WFQN+R K KK Sbjct: 214 PRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 248
>gi|8247930|sp|O60663|LMX1B_HUMAN LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2) Length = 379 Score = 40.4 bits (93), Expect = 9e-04 Identities = 21/57 (36%), Positives = 30/57 (52%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 KR RT T+ Q + F + CR R +A L+ R +++WFQN+R K KK Sbjct: 197 KRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253
>gi|47117908|sp|Q9BZI1|IRX2_HUMAN Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2) Length = 471 Score = 39.7 bits (91), Expect = 0.001 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 23/144 (15%) Query: 19 QAANGFAYNANQQPYPASAALGADG--------EYHRPACSLQS--PSSAGGHPKAHELS 68 ++A+G A++ PYP SAA A +Y A + + PS G AH Sbjct: 38 RSASGSAFS----PYPGSAAFTAQAATGFGSPLQYSADAAAAAAGFPSYMGAPYDAHTTG 93 Query: 69 ESCAGDKSPPGQASS---------KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 119 + A P G A+ ++ T +A L E N Y + ++ +A + Sbjct: 94 MTGAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAII 153 Query: 120 LNLTERQIKIWFQNRRMKYKKDQK 143 +T Q+ WF N R + KK+ K Sbjct: 154 TKMTLTQVSTWFANARRRLKKENK 177
>gi|28202257|sp|P14859|PO2F1_HUMAN POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1) Length = 743 Score = 38.9 bits (89), Expect = 0.002 Identities = 28/90 (31%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Query: 68 SESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQI 127 S S G + ++ RT+ + V LEK F N+ +A+ LN+ + I Sbjct: 364 SPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVI 423 Query: 128 KIWFQNRRMKYKKDQKGKGMLTSSGGQSPS 157 ++WF NRR K K+ SSGG S S Sbjct: 424 RVWFCNRRQKEKRINP-----PSSGGTSSS 448
>gi|47117872|sp|P78412|IRX6_HUMAN Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3) Length = 445 Score = 36.2 bits (82), Expect = 0.016 Identities = 42/153 (27%), Positives = 59/153 (38%), Gaps = 12/153 (7%) Query: 12 IYGGYPYQAANGFAYNANQQPY---PAS--AALGADGEYHRPACSLQSPSSAGG--HPKA 64 IYG PY AA PY P S AL E+ A S S + G +P Sbjct: 70 IYGA-PYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSLAQPGAYYPYE 128 Query: 65 HELSE---SCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLN 121 L + G G K A T T++ L E N Y + ++ +A + Sbjct: 129 RTLGQYQYERYGAVELSGAGRRKNA-TRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITK 187 Query: 122 LTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQ 154 +T Q+ WF N R + KK+ K + GG+ Sbjct: 188 MTLTQVSTWFANARRRLKKENKMTWAPKNKGGE 220
>gi|60416412|sp|P48742|LHX1_HUMAN LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) Length = 406 Score = 35.4 bits (80), Expect = 0.027 Identities = 33/111 (29%), Positives = 47/111 (42%), Gaps = 11/111 (9%) Query: 36 SAALGADGEYHRPACSLQSPSSAGGHPKAHE---LSESCAGDKSPPGQ---ASSKRARTA 89 SA G+D P+ S S + K E +S+ AG Q A + RT Sbjct: 132 SATTGSD-----PSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGPRTT 186 Query: 90 YTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 + QL L+ F R R ++A L R I++WFQNRR K ++ Sbjct: 187 IKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237
>gi|12644347|sp|P78413|IRX4_HUMAN Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3) Length = 519 Score = 35.4 bits (80), Expect = 0.027 Identities = 31/137 (22%), Positives = 57/137 (41%), Gaps = 8/137 (5%) Query: 12 IYGGYPYQAANGFA----YNANQQP-YPASAALGADGEYHRPACSLQSPSSAGGHPKAHE 66 +YGG PY + G+ Y + Y ++ DG A +P++A +P Sbjct: 72 VYGG-PYGGSQGYGNYVTYGSEASAFYSLNSFDSKDGS--GSAHGGLAPAAAAYYPYEPA 128 Query: 67 LSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQ 126 L + + ++ T T++ L +E N Y + ++ +A + +T Q Sbjct: 129 LGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQ 188 Query: 127 IKIWFQNRRMKYKKDQK 143 + WF N R + KK+ K Sbjct: 189 VSTWFANARRRLKKENK 205
>gi|730281|sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription factor-3 (Homeobox protein PBX3) Length = 434 Score = 34.7 bits (78), Expect = 0.047 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 4/54 (7%) Query: 92 SAQLVELEKEFHF----NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 S Q E+ E+ + N Y + E+A ++T Q+ WF N+R++YKK+ Sbjct: 243 SKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKN 296
>gi|2495306|sp|Q14863|PO6F1_HUMAN POU domain, class 6, transcription factor 1 (mPOU homeobox protein) (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5 protein) Length = 301 Score = 34.7 bits (78), Expect = 0.047 Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 79 GQASSKRAR-TAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMK 137 G+ S KR R T++T + L F N E+A LN +++WF NRR Sbjct: 229 GEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQT 288 Query: 138 YKKDQK 143 K K Sbjct: 289 LKNTSK 294
>gi|47606423|sp|P61371|ISL1_HUMAN Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606425|sp|P61373|ISL1_MESAU Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606424|sp|P61372|ISL1_MOUSE Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606422|sp|P61374|ISL1_RAT Insulin gene enhancer protein ISL-1 (Islet-1) Length = 349 Score = 34.7 bits (78), Expect = 0.047 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 7/57 (12%) Query: 91 TSAQLVELEKEFHFNR--YLCRPR-----RVEMANLLNLTERQIKIWFQNRRMKYKK 140 T + V EK+ H R Y PR + ++ + L+ R I++WFQN+R K KK Sbjct: 182 TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238
>gi|47117873|sp|P78414|IRX1_HUMAN Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1) Length = 480 Score = 34.7 bits (78), Expect = 0.047 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 13/133 (9%) Query: 18 YQAANGFAYNANQQ---PYPASAALGAD--GEYHRPACSLQSPSSAGGH--PKAHELSES 70 Y AA +A N PY A +L + +Y P++ H P + + Sbjct: 64 YAAAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPYGQF 123 Query: 71 CAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIW 130 GD P A+ R T+ A L E K N Y + ++ +A + +T Q+ W Sbjct: 124 QYGDPGRPKNAT--RESTSTLKAWLNEHRK----NPYPTKGEKIMLAIITKMTLTQVSTW 177 Query: 131 FQNRRMKYKKDQK 143 F N R + KK+ K Sbjct: 178 FANARRRLKKENK 190
>gi|28201884|sp|P78424|PO6F2_HUMAN POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor-1) (RPF-1) Length = 684 Score = 34.3 bits (77), Expect = 0.061 Identities = 17/63 (26%), Positives = 28/63 (44%) Query: 81 ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 + ++ RT++T L L F N + E+A LN +++WF N+R K Sbjct: 598 SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKN 657 Query: 141 DQK 143 K Sbjct: 658 TIK 660
>gi|18202938|sp|Q9H2C1|LHX5_HUMAN LIM/homeobox protein Lhx5 Length = 402 Score = 33.9 bits (76), Expect = 0.080 Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 2/71 (2%) Query: 72 AGDKSPPGQASSKRA--RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 129 A +++ + +KR RT + QL L+ F R R ++A L R I++ Sbjct: 167 ANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQV 226 Query: 130 WFQNRRMKYKK 140 WFQNRR K ++ Sbjct: 227 WFQNRRSKERR 237
>gi|2495300|sp|Q12837|PO42_HUMAN POU domain, class 4, transcription factor 2 (Brain-specific homeobox/POU domain protein 3B) (Brn-3B) Length = 410 Score = 33.5 bits (75), Expect = 0.10 Identities = 18/67 (26%), Positives = 32/67 (47%) Query: 81 ASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 A KR RT+ + + LE F + +A L+L + +++WF N+R K K+ Sbjct: 344 AEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 403 Query: 141 DQKGKGM 147 + G+ Sbjct: 404 MKYSAGI 410
>gi|1709437|sp|Q03052|PO3F1_HUMAN POU domain, class 3, transcription factor 1 (Octamer-binding transcription factor 6) (Oct-6) (POU-domain transcription factor SCIP) Length = 448 Score = 33.5 bits (75), Expect = 0.10 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 15/75 (20%) Query: 116 MANLLNLTERQIKIWFQNRRMKYKK-------------DQKGKGMLTSSGG--QSPSRSP 160 +A+ L L + +++WF NRR K K+ D G L GG PS P Sbjct: 369 LADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPP 428 Query: 161 VPPGAGGYLNSMHSL 175 PP A + + H+L Sbjct: 429 PPPPAALHHHHHHTL 443
>gi|20141754|sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1) gi|730279|sp|P40424|PBX1_HUMAN Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1) (Homeobox protein PRL) Length = 430 Score = 33.1 bits (74), Expect = 0.14 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 4/52 (7%) Query: 94 QLVELEKEFHF----NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 Q E+ E+ + N Y + E+A +T Q+ WF N+R++YKK+ Sbjct: 243 QATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKN 294
>gi|37999770|sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription factor-4 (Homeobox protein PBX4) Length = 330 Score = 33.1 bits (74), Expect = 0.14 Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 4/54 (7%) Query: 92 SAQLVELEKEFHF----NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 141 S Q E+ E+ + N Y + E+A LT Q+ WF N+R++YKK+ Sbjct: 174 SKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKN 227
>gi|123408|sp|P28069|PIT1_HUMAN Pituitary-specific positive transcription factor 1 (Pit-1) (Growth hormone factor 1) (GHF-1) Length = 291 Score = 32.7 bits (73), Expect = 0.18 Identities = 17/57 (29%), Positives = 28/57 (49%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ RT + A LE+ F + MA LNL + +++WF NRR + K+ Sbjct: 215 RKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKR 271
>gi|2833271|sp|Q15853|USF2_HUMAN Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS-interacting protein) (FIP) (Major late transcription factor 2) Length = 346 Score = 31.6 bits (70), Expect = 0.40 Identities = 23/95 (24%), Positives = 38/95 (40%) Query: 9 SSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELS 68 S+A + G A Q+P PA+A++ P +Q+P S GG P A +S Sbjct: 103 STAAFAGGQQAVTQVGVDGAAQRPGPAAASVPPGPAAPFPLAVIQNPFSNGGSPAAEAVS 162 Query: 69 ESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFH 103 P A + T+ Q ++ +F+ Sbjct: 163 GEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFY 197
>gi|2495302|sp|Q15319|PO43_HUMAN POU domain, class 4, transcription factor 3 (Brain-specific homeobox/POU domain protein 3C) (Brn-3C) Length = 338 Score = 31.2 bits (69), Expect = 0.52 Identities = 16/57 (28%), Positives = 28/57 (49%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 KR RT+ + + LE F + +A L+L + +++WF N+R K K+ Sbjct: 275 KRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331
>gi|46396941|sp|Q8N196|SIX5_HUMAN Homeobox protein SIX5 (DM locus-associated homeodomain protein) Length = 739 Score = 31.2 bits (69), Expect = 0.52 Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 9/55 (16%) Query: 105 NRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRS 159 NRY + +A L L+ Q+ WF+NRR + + T +GG +P +S Sbjct: 223 NRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDR---------TGAGGGAPCKS 268
>gi|28202258|sp|P20265|PO3F2_HUMAN POU domain, class 3, transcription factor 2 (Nervous-system specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2 protein) Length = 443 Score = 30.8 bits (68), Expect = 0.67 Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 14/90 (15%) Query: 81 ASSKRARTAYTSAQL-VELEKEFHFNRYLC-RPRRVEMANL---LNLTERQIKIWFQNRR 135 A+ R R TS ++ V+ E HF + C +P E+ +L L L + +++WF NRR Sbjct: 349 AAQGRKRKKRTSIEVSVKGALESHFLK--CPKPSAQEITSLADSLQLEKEVVRVWFCNRR 406 Query: 136 MKYKKDQKGKGMLTSSGGQSPSRSPVPPGA 165 K K+ +T GG P V G+ Sbjct: 407 QKEKR-------MTPPGGTLPGAEDVYGGS 429
>gi|12230612|sp|Q9UIU6|SIX4_HUMAN Homeobox protein SIX4 (Sine oculis homeobox homolog 4) Length = 760 Score = 30.8 bits (68), Expect = 0.67 Identities = 15/58 (25%), Positives = 28/58 (48%) Query: 98 LEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQS 155 L++ + NRY + +A + L+ Q+ WF+NRR + + + + S G S Sbjct: 217 LKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPS 274
>gi|28201861|sp|Q9UKI9|PO2F3_HUMAN POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Transcription factor Skn-1) (PLA-1 protein) Length = 436 Score = 30.8 bits (68), Expect = 0.67 Identities = 16/57 (28%), Positives = 29/57 (50%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 ++ RT+ + + LEK F N +A L++ + +++WF NRR K K+ Sbjct: 282 RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338
>gi|2506535|sp|Q01851|PO4F1_HUMAN POU domain, class 4, transcription factor 1 (Brain-specific homeobox/POU domain protein 3A) (Brn-3A) (Oct-T1) (Homeobox/POU domain protein RDC-1) Length = 423 Score = 30.8 bits (68), Expect = 0.67 Identities = 16/57 (28%), Positives = 28/57 (49%) Query: 84 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 140 KR RT+ + + LE F + +A L+L + +++WF N+R K K+ Sbjct: 360 KRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 416
>gi|8134810|sp|O60320|Y574_HUMAN Hypothetical protein KIAA0574 Length = 405 Score = 30.8 bits (68), Expect = 0.67 Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 15/81 (18%) Query: 15 GYPYQAANGFAYNANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGD 74 G Q G + P ++++ D HRP+CS + LSE+ Sbjct: 250 GSQVQPGPGHVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAG---------LSEAV--- 297 Query: 75 KSPPGQASSKRARTAYTSAQL 95 PG AS R+ TA AQL Sbjct: 298 ---PGSASMSRSATAACRAQL 315
>gi|2495290|sp|Q15475|SIX1_HUMAN Homeobox protein SIX1 (Sine oculis homeobox homolog 1) Length = 284 Score = 30.0 bits (66), Expect = 1.2 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 4/71 (5%) Query: 98 LEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK----KDQKGKGMLTSSGG 153 L + + N Y + E+A LT Q+ WF+NRR + + K+++ SS Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENTENNNSSSN 198 Query: 154 QSPSRSPVPPG 164 + SP+ G Sbjct: 199 KQNQLSPLEGG 209
>gi|2506534|sp|P20264|PO33_HUMAN POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein) Length = 500 Score = 30.0 bits (66), Expect = 1.2 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 7/65 (10%) Query: 81 ASSKRARTAYTSAQL-VELEKEFHFNRYLC-RPRRVEMANL---LNLTERQIKIWFQNRR 135 A+ R R TS ++ V+ E HF + C +P E+ NL L L + +++WF NRR Sbjct: 401 AAQGRKRKKRTSIEVSVKGALESHFLK--CPKPSAQEITNLADSLQLEKEVVRVWFCNRR 458 Query: 136 MKYKK 140 K K+ Sbjct: 459 QKEKR 463
>gi|6094293|sp|O95343|SIX3_HUMAN Homeobox protein SIX3 (Sine oculis homeobox homolog 3) Length = 332 Score = 29.6 bits (65), Expect = 1.5 Identities = 16/53 (30%), Positives = 25/53 (47%) Query: 112 RRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 164 ++ E+A LT Q+ WF+NRR + + + + G S RS PG Sbjct: 235 KKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLAEPG 287
>gi|1345629|sp|P49335|PO3F4_HUMAN POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) Length = 361 Score = 29.6 bits (65), Expect = 1.5 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 14/81 (17%) Query: 81 ASSKRARTAYTSAQL-VELEKEFHFNRYLC-RPRRVEMANL---LNLTERQIKIWFQNRR 135 A+ R R TS ++ V+ E HF + C +P E+++L L L + +++WF NRR Sbjct: 273 AAQGRKRKKRTSIEVSVKGVLETHFLK--CPKPAAQEISSLADSLQLEKEVVRVWFCNRR 330 Query: 136 MKYKKDQKGKGMLTSSGGQSP 156 K K+ +T G Q P Sbjct: 331 QKEKR-------MTPPGDQQP 344
>gi|32699572|sp|Q8NG57|ELOA3_HUMAN RNA polymerase II transcription factor SIII subunit A3 (Elongin A3) (EloA3) (Transcription elongation factor B polypeptide 3C) Length = 546 Score = 29.6 bits (65), Expect = 1.5 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Query: 30 QQPYPASAALGADGEYHRPACSLQSPSSA-GGHPKAHELSESCAGDKSPPGQAS-SKRAR 87 +QP A G C Q A G H K H+ S + KSPP Q S S+R + Sbjct: 191 EQPGRGHAHAAQGGPLLGQGCQGQPQGEAVGSHSKGHKSSRGASAQKSPPVQESQSERLQ 250 Query: 88 TA 89 A Sbjct: 251 AA 252
>gi|30173473|sp|Q96T25|ZIC5_HUMAN Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5) Length = 639 Score = 29.3 bits (64), Expect = 2.0 Identities = 14/37 (37%), Positives = 17/37 (45%) Query: 250 PHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASG 286 PH G + G+Y P + GPALF H A G Sbjct: 211 PHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPG 247
>gi|12230598|sp|Q9NPC8|SIX2_HUMAN Homeobox protein SIX2 (Sine oculis homeobox homolog 2) Length = 291 Score = 29.3 bits (64), Expect = 2.0 Identities = 19/70 (27%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 98 LEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPS 157 L + + N Y + E+A LT Q+ WF+NRR ++D+ + + S S Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRR---QRDRAAEAKERENNENSNS 195 Query: 158 RSPVPPGAGG 167 S P G Sbjct: 196 NSHNPLNGSG 205
>gi|44888551|sp|Q9UKY1|ZHX1_HUMAN Zinc fingers and homeoboxes protein 1 Length = 873 Score = 28.9 bits (63), Expect = 2.6 Identities = 14/59 (23%), Positives = 27/59 (45%) Query: 87 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGK 145 R T QL EL+ + N++ + + + LT+ +IK WF + R + + + Sbjct: 468 RAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQ 526
Score = 26.9 bits (58), Expect = 9.7 Identities = 10/16 (62%), Positives = 13/16 (81%) Query: 123 TERQIKIWFQNRRMKY 138 TE QIKIWF +R+K+ Sbjct: 324 TEEQIKIWFSAQRLKH 339
>gi|135304|sp|P17275|JUNB_HUMAN Transcription factor jun-B Length = 347 Score = 28.9 bits (63), Expect = 2.6 Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 35 ASAALGADGEYHRPACSL--QSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTS 92 A AA+G Y S +P AGGHP L + K P R+R A Sbjct: 198 AGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPP 257 Query: 93 AQLVELEKE 101 + +E + Sbjct: 258 VSPINMEDQ 266
>gi|50401058|sp|Q8IU89|LSS3_HUMAN LAG1 longevity assurance homolog 3 Length = 383 Score = 28.9 bits (63), Expect = 2.6 Identities = 11/20 (55%), Positives = 16/20 (80%) Query: 116 MANLLNLTERQIKIWFQNRR 135 +A NLTERQ++ WF++RR Sbjct: 102 LAKKCNLTERQVERWFRSRR 121
>gi|3183005|sp|Q99502|EYA1_HUMAN Eyes absent homolog 1 Length = 592 Score = 28.5 bits (62), Expect = 3.3 Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 1 MQKATYYDSSAIYGGYPYQAANGFAYNANQQPYPASAALGADGEY 45 MQ +++ SS IY G N +N++QQ YP+ + G G+Y Sbjct: 184 MQGSSFTTSSGIYTGNN-SLTNSSGFNSSQQDYPSYPSFG-QGQY 226
>gi|27805750|sp|Q9GZN2|TGIF2_HUMAN Homeobox protein TGIF2 (TGFB-induced factor 2) (5'-TG-3' interacting factor 2) (TGF(beta)-induced transcription factor 2) Length = 237 Score = 28.5 bits (62), Expect = 3.3 Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 10/109 (9%) Query: 67 LSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEF----HFNRYLCRPRRVEMANLLNL 122 +S+S G+ + KR R + V++ +++ +N Y ++ ++ NL Sbjct: 1 MSDSDLGEDEGLLSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNL 60 Query: 123 TERQIKIWFQNRRMK-----YKKDQKGKGMLT-SSGGQSPSRSPVPPGA 165 + QI WF N R + +KD K T S G S +P G+ Sbjct: 61 SVLQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGS 109
>gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein (CDP) (Cut-like 1) Length = 1505 Score = 27.7 bits (60), Expect = 5.7 Identities = 18/80 (22%), Positives = 33/80 (41%) Query: 76 SPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 135 SP Q K+ R + L++ + Y ++A LNL + WF N R Sbjct: 1237 SPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYR 1296 Query: 136 MKYKKDQKGKGMLTSSGGQS 155 + +++ + + S GQ+ Sbjct: 1297 SRIRRELFIEEIQAGSQGQA 1316
>gi|5921169|sp|O15265|ATX7_HUMAN Ataxin-7 (Spinocerebellar ataxia type 7 protein) Length = 892 Score = 27.7 bits (60), Expect = 5.7 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 252 IQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMD 289 + SPV + + + P S S PA + AASGAMD Sbjct: 599 VSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMD 636
>gi|28201858|sp|Q06416|PO5L_HUMAN POU domain, class 5, transcription factor 1-like protein 1 (Octamer binding protein 3-like) Length = 359 Score = 27.3 bits (59), Expect = 7.5 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 16/113 (14%) Query: 67 LSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRV----EMANLLNL 122 L E C K+ + KR RT+ + LE N +L P+ +A L L Sbjct: 217 LQEIC---KAETLMQARKRKRTSIENRVRGNLE-----NLFLQCPKPTLQISHIAQQLGL 268 Query: 123 TERQIKIWFQNRRMKYKKDQKGKGMLT--SSGGQSPSRSPV--PPGAGGYLNS 171 + +++WF NRR K K+ + G S PV PP G + + Sbjct: 269 EKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGT 321
>gi|13124794|sp|P52756|RBM5_HUMAN RNA-binding protein 5 (RNA binding motif protein 5) (Putative tumor suppressor LUCA15) (G15 protein) Length = 815 Score = 27.3 bits (59), Expect = 7.5 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 8/86 (9%) Query: 4 ATY-YDSSAIYGGYPYQAANGFAYNANQQPYPASAA---LGADGEYHRPACSLQSPS-SA 58 +TY YD S+ GY Y G Y+ N Q Y S L DGE + +S S Sbjct: 460 STYQYDESS---GYYYDPTTGLYYDPNSQYYYNSLTQQYLYWDGEKETYVPAAESSSHQQ 516 Query: 59 GGHPKAHELSESCAGDKSPPGQASSK 84 G P A E E KS Q +K Sbjct: 517 SGLPPAKEGKEKKEKPKSKTAQQIAK 542
>gi|41688792|sp|Q9BYP7|WNK3_HUMAN Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 27.3 bits (59), Expect = 7.5 Identities = 17/75 (22%), Positives = 32/75 (42%) Query: 53 QSPSSAGGHPKAHELSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPR 112 Q+P ++ + K L E+C +K P Q + + +A + + E F Sbjct: 1341 QNPKTSFSYEKLQALQETCKENKGVPKQGDNFLSFSAACETDVSSVTPEKEFEETSATGS 1400 Query: 113 RVEMANLLNLTERQI 127 ++ + L L ER+I Sbjct: 1401 SMQSGSELLLKEREI 1415
>gi|28201859|sp|Q9BZV7|PO5M_HUMAN POU domain, class 5, transcription factor 1-like protein 2 Length = 359 Score = 27.3 bits (59), Expect = 7.5 Identities = 30/113 (26%), Positives = 45/113 (39%), Gaps = 16/113 (14%) Query: 67 LSESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRV----EMANLLNL 122 L E C K+ + KR RT+ + LE N +L P+ +A L L Sbjct: 217 LQEIC---KAETLMQARKRKRTSIENRVRGNLE-----NLFLQCPKPTLQISHIAQQLGL 268 Query: 123 TERQIKIWFQNRRMKYKKDQKGKGMLT--SSGGQSPSRSPV--PPGAGGYLNS 171 + +++WF NRR K K+ + G S PV PP G + + Sbjct: 269 EKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGT 321
>gi|1705708|sp|P15391|CD19_HUMAN B-lymphocyte antigen CD19 precursor (B-lymphocyte surface antigen B4) (Leu-12) (Differentiation antigen CD19) Length = 556 Score = 27.3 bits (59), Expect = 7.5 Identities = 20/79 (25%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 27 NANQQPYPASAALGADGEYHRPACSLQSPSSAGGHPKAHELSESCAGDKSPPGQASSKRA 86 N P P S G R A L + + G+P + ++ G +SPPG + Sbjct: 350 NVLSLPTPTSGL----GRAQRWAAGLGGTAPSYGNPSSDVQADGALGSRSPPGVGPEEEE 405 Query: 87 RTAYTSAQLVELEKEFHFN 105 Y E + EF+ N Sbjct: 406 GEGYEEPDSEE-DSEFYEN 423
>gi|20139982|sp|O75635|SPB7_HUMAN Megsin (TP55) (Serpin B7) Length = 380 Score = 26.9 bits (58), Expect = 9.7 Identities = 15/45 (33%), Positives = 22/45 (48%) Query: 107 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSS 151 Y + RV+ N L T R I W +N K+ G+G ++SS Sbjct: 122 YDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSS 166
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.313 0.130 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 793,594 Number of Sequences: 164271 Number of extensions: 36357 Number of successful extensions: 134 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 4 Number of HSP's that attempted gapping in prelim test: 102 Number of HSP's gapped (non-prelim): 35 length of query: 335 length of database: 6,424,444 effective HSP length: 96 effective length of query: 239 effective length of database: 5,281,564 effective search space: 1262293796 effective search space used: 1262293796 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 58 (26.9 bits)