BLASTP 2.2.10 [Oct-19-2004]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1111165125-21085-43698330115.BLASTQ2

Query= GENEid (7): chain (-)
         (385 letters)


Database: Non-redundant SwissProt sequences 
           164,271 sequences; 60,490,055 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs

Taxonomy reports

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6016292|sp|O43364|HXA2_HUMAN  Homeobox protein Hox-A2          434   e-122 
gi|123270|sp|P14652|HXB2_HUMAN  Homeobox protein Hox-B2 (Hox...   166   1e-41 
gi|6166222|sp|P31249|HXD3_HUMAN  Homeobox protein Hox-D3 (Ho...   108   2e-24 
gi|123268|sp|P14651|HXB3_HUMAN  Homeobox protein Hox-B3 (Hox...   106   2e-23 
gi|6016293|sp|O43365|HXA3_HUMAN  Homeobox protein Hox-A3 (Ho...   105   3e-23 
gi|1708540|sp|P52945|IPF1_HUMAN  Insulin promoter factor-1 (...    92   2e-19 
gi|6166217|sp|Q00056|HXA4_HUMAN  Homeobox protein Hox-A4 (Ho...    91   7e-19 
gi|20141491|sp|P09016|HXD4_HUMAN  Homeobox protein Hox-D4 (H...    91   9e-19 
gi|400000|sp|P09067|HXB5_HUMAN  Homeobox protein Hox-B5 (Hox...    91   9e-19 
gi|547692|sp|P17483|HXB4_HUMAN  Homeobox protein Hox-B4 (Hox...    90   1e-18 
gi|52788238|sp|P20719|HXA5_HUMAN  Homeobox protein Hox-A5 (H...    89   2e-18 
gi|20138327|sp|Q9BZM3|GSH2_HUMAN  Homeobox protein GSH-2           89   3e-18 
gi|123271|sp|P14653|HXB1_HUMAN  Homeobox protein Hox-B1 (Hox...    89   3e-18 
gi|27923786|sp|Q9H4S2|GSHI_HUMAN  Homeobox protein GSH-1           88   6e-18 
gi|17378385|sp|P31267|HXA6_HUMAN  Homeobox protein Hox-A6 (H...    87   1e-17 
gi|123279|sp|P09017|HXC4_HUMAN  Homeobox protein Hox-C4 (Hox...    87   1e-17 
gi|45644931|sp|P50219|HLXB9_HUMAN  Homeobox protein HB9            87   1e-17 
gi|232262|sp|Q00444|HXC5_HUMAN  Homeobox protein Hox-C5 (Hox...    86   2e-17 
gi|20141493|sp|P09630|HXC6_HUMAN  Homeobox protein Hox-C6 (H...    86   2e-17 
gi|13124738|sp|P17509|HXB6_HUMAN  Homeobox protein Hox-B6 (H...    86   3e-17 
gi|3915721|sp|P31268|HXA7_HUMAN  Homeobox protein Hox-A7 (Ho...    86   3e-17 
gi|6166216|sp|P49639|HXA1_HUMAN  Homeobox protein Hox-A1 (Ho...    85   4e-17 
gi|123255|sp|P09629|HXB7_HUMAN  Homeobox protein Hox-B7 (Hox...    85   4e-17 
gi|17378648|sp|Q9GZZ0|HXD1_HUMAN  Homeobox protein Hox-D1          82   2e-16 
gi|13124743|sp|P31260|HXA10_HUMAN  Homeobox protein Hox-A10 ...    82   4e-16 
gi|1345720|sp|P47902|CDX1_HUMAN  Homeobox protein CDX-1 (Cau...    82   4e-16 
gi|123286|sp|P28356|HXD9_HUMAN  Homeobox protein Hox-D9 (Hox...    81   7e-16 
gi|20141537|sp|P31274|HXC9_HUMAN  Homeobox protein Hox-C9 (H...    80   9e-16 
gi|6166219|sp|P31269|HXA9_HUMAN  Homeobox protein Hox-A9 (Ho...    80   9e-16 
gi|20141507|sp|P17482|HXB9_HUMAN  Homeobox protein Hox-B9 (H...    80   9e-16 
gi|20141612|sp|Q9NYD6|HXC10_HUMAN  Homeobox protein Hox-C10        80   1e-15 
gi|20141506|sp|P17481|HXB8_HUMAN  Homeobox protein Hox-B8 (H...    80   1e-15 
gi|1709078|sp|P50221|MEOX1_HUMAN  Homeobox protein MOX-1 (Me...    80   1e-15 
gi|12231013|sp|Q03828|EVX2_HUMAN  Homeobox even-skipped homo...    80   1e-15 
gi|13124737|sp|P13378|HXD8_HUMAN  Homeobox protein Hox-D8 (H...    79   3e-15 
gi|12230077|sp|Q14549|GBX1_HUMAN  Homeobox protein GBX-1 (Ga...    79   3e-15 
gi|1352398|sp|P49640|EVX1_HUMAN  Homeobox even-skipped homol...    78   4e-15 
gi|1709079|sp|P50222|MEOX2_HUMAN  Homeobox protein MOX-2 (Me...    78   6e-15 
gi|123289|sp|P28358|HXD10_HUMAN  Homeobox protein Hox-D10 (H...    77   8e-15 
gi|13124745|sp|P31273|HXC8_HUMAN  Homeobox protein Hox-C8 (H...    77   1e-14 
gi|13124744|sp|P31270|HXA11_HUMAN  Homeobox protein Hox-A11 ...    76   2e-14 
gi|12644308|sp|P52951|GBX2_HUMAN  Homeobox protein GBX-2 (Ga...    76   2e-14 
gi|2506529|sp|Q07687|DLX2_HUMAN  Homeobox protein DLX-2            74   8e-14 
gi|3913487|sp|O60479|DLX3_HUMAN  Homeobox protein DLX-3            73   1e-13 
gi|20141282|sp|Q99626|CDX2_HUMAN  Homeobox protein CDX-2 (Ca...    73   2e-13 
gi|12644203|sp|P31277|HXD11_HUMAN  Homeobox protein Hox-D11 ...    73   2e-13 
gi|3287858|sp|O43248|HXC11_HUMAN  Homeobox protein Hox-C11         72   2e-13 
gi|3023467|sp|O14627|CDX4_HUMAN  Homeobox protein CDX-4 (Cau...    71   7e-13 
gi|57015304|sp|Q04741|EMX1_HUMAN  Homeobox protein EMX1 (Emp...    71   7e-13 
gi|19862512|sp|Q04743|EMX2_HUMAN  Homeobox protein EMX2 (Emp...    70   9e-13 
gi|17377578|sp|Q99801|NKX31_HUMAN  Homeobox protein Nkx-3.1        69   4e-12 
gi|12644329|sp|P56178|DLX5_HUMAN  Homeobox protein DLX-5           69   4e-12 
gi|29336920|sp|Q9BZE3|BARH1_HUMAN  BarH-like 1 homeobox prot...    68   5e-12 
gi|12644227|sp|P35452|HXD12_HUMAN  Homeobox protein Hox-D12 ...    68   6e-12 
gi|38605720|sp|P56177|DLX1_HUMAN  Homeobox protein DLX-1           68   6e-12 
gi|6016210|sp|P78367|NK32_HUMAN  Homeobox protein Nkx-3.2 (B...    67   8e-12 
gi|2833256|sp|Q14774|HLX1_HUMAN  Homeobox protein HLX1 (Home...    67   1e-11 
gi|399982|sp|P31314|TLX1_HUMAN  T-cell leukemia homeobox pro...    66   2e-11 
gi|20141538|sp|P31275|HXC12_HUMAN  Homeobox protein Hox-C12 ...    66   2e-11 
gi|13431329|sp|Q9UMQ3|BARX2_HUMAN  Homeobox protein BarH-like 2    65   4e-11 
gi|47117915|sp|Q9NY43|BARH2_HUMAN  BarH-like 2 homeobox protein    65   4e-11 
gi|23831508|sp|O43711|TLX3_HUMAN  T-cell leukemia homeobox p...    65   4e-11 
gi|12644330|sp|P56179|DLX6_HUMAN  Homeobox protein DLX-6           65   5e-11 
gi|27923817|sp|Q9H2Z4|NK24_HUMAN  Homeobox protein Nkx-2.4 (...    65   5e-11 
gi|547658|sp|Q03014|HHEX_HUMAN  Homeobox protein PRH (Hemato...    64   7e-11 
gi|14194481|sp|Q9HBU1|BARX1_HUMAN  Homeobox protein BarH-like 1    64   7e-11 
gi|6016205|sp|O95096|NKX22_HUMAN  Homeobox protein Nkx-2.2 (...    64   1e-10 
gi|2828197|sp|P31271|HXA13_HUMAN  Homeobox protein Hox-A13 (...    64   1e-10 
gi|13959687|sp|P35548|MSX2_HUMAN  Homeobox protein MSX-2 (Ho...    63   1e-10 
gi|14917010|sp|Q05925|HME1_HUMAN  Homeobox protein engrailed...    63   1e-10 
gi|20141539|sp|P31276|HXC13_HUMAN  Homeobox protein Hox-C13 ...    63   2e-10 
gi|21903415|sp|P19622|HME2_HUMAN  Homeobox protein engrailed...    63   2e-10 
gi|1708211|sp|P52952|NK25_HUMAN  Homeobox protein Nkx-2.5 (H...    63   2e-10 
gi|3915680|sp|Q92988|DLX4_HUMAN  Homeobox protein DLX-4 (DLX...    63   2e-10 
gi|23503066|sp|P28360|MSX1_HUMAN  Homeobox protein MSX-1 (Ho...    62   3e-10 
gi|27923815|sp|Q8TAU0|NKX23_HUMAN  Homeobox protein Nkx-2.3 ...    62   3e-10 
gi|1730095|sp|P52954|LBX1_HUMAN  Transcription factor LBX1         62   3e-10 
gi|2851475|sp|P35453|HXD13_HUMAN  Homeobox protein Hox-D13 (...    62   3e-10 
gi|1174819|sp|P43699|TITF1_HUMAN  Thyroid transcription fact...    62   3e-10 
gi|20532295|sp|Q9UIW0|VAX2_HUMAN  Ventral anterior homeobox 2      61   6e-10 
gi|6174907|sp|Q99697|PITX2_HUMAN  Pituitary homeobox 2 (RIEG...    61   7e-10 
gi|20532396|sp|O43763|TLX2_HUMAN  T-cell leukemia homeobox p...    61   7e-10 
gi|6016208|sp|O15522|NK28_HUMAN  Homeobox protein Nkx-2.8 (H...    61   7e-10 
gi|8134640|sp|O14813|PHX2A_HUMAN  Paired mesoderm homeobox p...    61   7e-10 
gi|50403792|sp|Q92826|HXB13_HUMAN  Homeobox protein Hox-B13        60   1e-09 
gi|6093723|sp|O75364|PITX3_HUMAN  Pituitary homeobox 3 (Home...    60   1e-09 
gi|6016211|sp|P78426|NK61_HUMAN  Homeobox protein Nkx-6.1          59   2e-09 
gi|8134644|sp|Q99453|PHX2B_HUMAN  Paired mesoderm homeobox p...    58   6e-09 
gi|48428084|sp|Q8N693|ESX1L_HUMAN  Extraembryonic, spermatog...    56   2e-08 
gi|27923733|sp|Q96QS3|ARX_HUMAN  Homeobox protein ARX (Arist...    55   3e-08 
gi|13626112|sp|Q9H161|ALX4_HUMAN  Homeobox protein aristales...    55   3e-08 
gi|3024482|sp|P78337|PITX1_HUMAN  Pituitary homeobox 1 (Hind...    55   5e-08 
gi|18202099|sp|O60902|SHOX2_HUMAN  Short stature homeobox pr...    54   9e-08 
gi|17380297|sp|Q9Y2V3|RX_HUMAN  Retinal homeobox protein Rx ...    52   3e-07 
gi|3023579|sp|Q15699|CRT1_HUMAN  Cartilage homeoprotein 1 (C...    52   3e-07 
gi|13626107|sp|O95076|ALX3_HUMAN  Homeobox protein aristales...    52   3e-07 
gi|6831676|sp|O15266|SHOX_HUMAN  Short stature homeobox prot...    52   4e-07 
gi|3287764|sp|O43186|CRX_HUMAN  Cone-rod homeobox protein          52   4e-07 
gi|51702790|sp|P63015|PAX6_MOUSE  Paired box protein Pax-6 (...    52   4e-07 
gi|17374365|sp|P58304|CHX10_HUMAN  Homeobox protein CHX10 (C...    52   4e-07 
gi|27923801|sp|Q8TE12|LMX1A_HUMAN  LIM homeobox transcriptio...    51   6e-07 
gi|7531125|sp|P56915|GSC_HUMAN  Homeobox protein goosecoid         51   8e-07 
gi|12644475|sp|Q99811|PRRX2_HUMAN  Paired mesoderm homeobox ...    50   2e-06 
gi|6174916|sp|P54821|PRRX1_HUMAN  Paired mesoderm homeobox p...    49   2e-06 
gi|12230168|sp|Q9UBX0|HESX1_HUMAN  Homeobox expressed in ES ...    49   2e-06 
gi|8247951|sp|P23759|PAX7_HUMAN  Paired box protein Pax-7 (H...    49   2e-06 
gi|417427|sp|P32243|OTX2_HUMAN  Homeobox protein OTX2              49   4e-06 
gi|1172022|sp|P23760|PAX3_HUMAN  Paired box protein Pax-3 (H...    48   5e-06 
gi|8247930|sp|O60663|LMX1B_HUMAN  LIM homeobox transcription...    48   6e-06 
gi|3914276|sp|O43316|PAX4_HUMAN  Paired box protein Pax-4          47   8e-06 
gi|417425|sp|P32242|OTX1_HUMAN  Homeobox protein OTX1              47   1e-05 
gi|6685480|sp|O15499|GSCL_HUMAN  Homeobox protein goosecoid-...    46   2e-05 
gi|37537960|sp|Q8NHV9|PEPP1_HUMAN  Paired-like homeobox prot...    46   2e-05 
gi|6093787|sp|O75360|PROP1_HUMAN  Homeobox protein prophet o...    46   2e-05 
gi|25009572|sp|Q9NZR4|VSX1_HUMAN  Visual system homeobox 1 (...    45   5e-05 
gi|20138668|sp|Q969G2|LHX4_HUMAN  LIM/homeobox protein Lhx4        45   5e-05 
gi|123402|sp|P09086|PO2F2_HUMAN  POU domain, class 2, transc...    42   3e-04 
gi|18202510|sp|Q15911|ATBF1_HUMAN  Alpha-fetoprotein enhance...    42   4e-04 
gi|37537987|sp|Q9BQY4|PEP2_HUMAN  Paired-like homeobox prote...    41   6e-04 
gi|18202938|sp|Q9H2C1|LHX5_HUMAN  LIM/homeobox protein Lhx5        41   6e-04 
gi|8247936|sp|P50458|LHX2_HUMAN  LIM/homeobox protein Lhx2 (...    41   8e-04 
gi|8134548|sp|Q9UPM6|LHX61_HUMAN  LIM/homeobox protein Lhx6....    40   0.001 
gi|12643346|sp|Q9NQ69|LHX9_HUMAN  LIM/homeobox protein Lhx9        40   0.001 
gi|60416412|sp|P48742|LHX1_HUMAN  LIM/homeobox protein Lhx1 ...    40   0.002 
gi|12643415|sp|Q9UBR4|LHX3_HUMAN  LIM/homeobox protein Lhx3        40   0.002 
gi|2506535|sp|Q01851|PO4F1_HUMAN  POU domain, class 4, trans...    39   0.004 
gi|28202257|sp|P14859|PO2F1_HUMAN  POU domain, class 2, tran...    38   0.005 
gi|28201861|sp|Q9UKI9|PO2F3_HUMAN  POU domain, class 2, tran...    38   0.005 
gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN  Zinc finger homeobox prot...    38   0.007 
gi|47117872|sp|P78412|IRX6_HUMAN  Iroquois-class homeodomain...    37   0.011 
gi|2495300|sp|Q12837|PO42_HUMAN  POU domain, class 4, transc...    36   0.019 
gi|2495302|sp|Q15319|PO43_HUMAN  POU domain, class 4, transc...    36   0.025 
gi|1345629|sp|P49335|PO3F4_HUMAN  POU domain, class 3, trans...    35   0.043 
gi|20978495|sp|Q96A47|ISL2_HUMAN  Insulin gene enhancer prot...    35   0.043 
gi|2495306|sp|Q14863|PO6F1_HUMAN  POU domain, class 6, trans...    35   0.056 
gi|2495290|sp|Q15475|SIX1_HUMAN  Homeobox protein SIX1 (Sine...    35   0.056 
gi|12230598|sp|Q9NPC8|SIX2_HUMAN  Homeobox protein SIX2 (Sin...    35   0.056 
gi|28202258|sp|P20265|PO3F2_HUMAN  POU domain, class 3, tran...    33   0.13  
gi|47606423|sp|P61371|ISL1_HUMAN  Insulin gene enhancer prot...    33   0.13  
gi|12644347|sp|P78413|IRX4_HUMAN  Iroquois-class homeodomain...    33   0.21  
gi|1709437|sp|Q03052|PO3F1_HUMAN  POU domain, class 3, trans...    33   0.21  
gi|2506534|sp|P20264|PO33_HUMAN  POU domain, class 3, transc...    32   0.28  
gi|12230612|sp|Q9UIU6|SIX4_HUMAN  Homeobox protein SIX4 (Sin...    32   0.28  
gi|28201884|sp|P78424|PO6F2_HUMAN  POU domain, class 6, tran...    32   0.28  
gi|20141754|sp|P41778|PBX1_MOUSE  Pre-B-cell leukemia transc...    32   0.36  
gi|28201859|sp|Q9BZV7|PO5M_HUMAN  POU domain, class 5, trans...    32   0.48  
gi|123408|sp|P28069|PIT1_HUMAN  Pituitary-specific positive ...    31   0.62  
gi|730281|sp|P40426|PBX3_HUMAN  Pre-B-cell leukemia transcri...    31   0.81  
gi|1350590|sp|P47736|RGP2_HUMAN  Rap1 GTPase-activating prot...    30   1.1   
gi|1352729|sp|P40425|PBX2_HUMAN  Pre-B-cell leukemia transcr...    30   1.4   
gi|6919875|sp|Q92997|DVL3_HUMAN  Segment polarity protein di...    30   1.8   
gi|28201858|sp|Q06416|PO5L_HUMAN  POU domain, class 5, trans...    30   1.8   
gi|38258267|sp|Q9UK17|KCD3_HUMAN  Potassium voltage-gated ch...    30   1.8   
gi|44888551|sp|Q9UKY1|ZHX1_HUMAN  Zinc fingers and homeoboxe...    29   2.4   
gi|400659|sp|Q01860|PO5F1_HUMAN  POU domain, class 5, transc...    29   2.4   
gi|37999770|sp|Q9BYU1|PBX4_HUMAN  Pre-B-cell leukemia transc...    29   2.4   
gi|22096235|sp|Q9UBB9|TP11_HUMAN  Tuftelin-interacting prote...    29   3.1   
gi|47117873|sp|P78414|IRX1_HUMAN  Iroquois-class homeodomain...    29   3.1   
gi|47117871|sp|P78411|IRX5_HUMAN  Iroquois-class homeodomain...    29   3.1   
gi|47117874|sp|P78415|IRX3_HUMAN  Iroquois-class homeodomain...    29   3.1   
gi|47117908|sp|Q9BZI1|IRX2_HUMAN  Iroquois-class homeodomain...    29   3.1   
gi|28380041|sp|Q9BYJ9|YTH1_HUMAN  YTH domain protein 1 (Derm...    29   3.1   
gi|2495295|sp|Q15583|TGIF_HUMAN  5'-TG-3' interacting factor...    28   4.0   
gi|51316484|sp|Q8N5B7|LSS5_HUMAN  LAG1 longevity assurance h...    28   4.0   
gi|12643733|sp|Q16799|RTN1_HUMAN  Reticulon 1 (Neuroendocrin...    28   5.3   
gi|50401058|sp|Q8IU89|LSS3_HUMAN  LAG1 longevity assurance h...    28   5.3   
gi|3913115|sp|Q92858|ATOH1_HUMAN  Atonal protein homolog 1 (...    28   6.9   
gi|13124379|sp|O95897|NOE2_HUMAN  Noelin 2 precursor (Olfact...    27   9.0   
gi|46396941|sp|Q8N196|SIX5_HUMAN  Homeobox protein SIX5 (DM ...    27   9.0   


Alignments

>gi|6016292|sp|O43364|HXA2_HUMAN   Homeobox protein Hox-A2
          Length = 376

 Score =  434 bits (1117), Expect = e-122
 Identities = 218/247 (88%), Positives = 218/247 (88%)

Query: 139 KESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV 198
           KESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV
Sbjct: 130 KESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKV 189

Query: 199 WFQNRRMKHKRQTQCKENQNSEGKCKXXXXXXXXXXXXXXXXXXXQALSVSGALLEREGY 258
           WFQNRRMKHKRQTQCKENQNSEGKCK                   QALSVSGALLEREGY
Sbjct: 190 WFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGY 249

Query: 259 TFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGL 318
           TFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGL
Sbjct: 250 TFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGL 309

Query: 319 NNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSXXXXXXXXXXI 378
           NNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADS          I
Sbjct: 310 NNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLDFFTDTLTTI 369

Query: 379 DLQHLNY 385
           DLQHLNY
Sbjct: 370 DLQHLNY 376



>gi|123270|sp|P14652|HXB2_HUMAN   Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8)
          Length = 356

 Score =  166 bits (420), Expect = 1e-41
 Identities = 108/249 (43%), Positives = 126/249 (50%), Gaps = 32/249 (12%)

Query: 140 ESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 199
           + L + +  GGG+RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW
Sbjct: 131 DGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 190

Query: 200 FQNRRMKHKRQTQCKENQNSEGKCKXXXXXXXXXXXXXXXXXXXQALSVSGALLEREGYT 259
           FQNRRMKHKRQTQ +E  + E  C                     A S  G    R  + 
Sbjct: 191 FQNRRMKHKRQTQHREPPDGEPACP-------GALEDICDPAEEPAASPGGPSASRAAW- 242

Query: 260 FQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLN 319
            +      +  P   + D +   V             +    + P C        GAG  
Sbjct: 243 -EACCHPPEVVPGALSADPRPLAV-----------RLEGAGASSPGCALR-----GAGGL 285

Query: 320 NDSPEALEV-------PSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSXXXXX 372
              P   +V       P L D + F+ DSCLQLS  +SPSL GSLDSPV  S +      
Sbjct: 286 EPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLDSPVPFSEEELDFFT 345

Query: 373 XXXXXIDLQ 381
                IDLQ
Sbjct: 346 STLCAIDLQ 354



>gi|6166222|sp|P31249|HXD3_HUMAN   Homeobox protein Hox-D3 (Hox-4A)
          Length = 416

 Score =  108 bits (271), Expect = 2e-24
 Identities = 50/75 (66%), Positives = 62/75 (82%)

Query: 140 ESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 199
           ES E     G  S+R+RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A LL+LTERQ+K+W
Sbjct: 166 ESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIW 225

Query: 200 FQNRRMKHKRQTQCK 214
           FQNRRMK+K+  + K
Sbjct: 226 FQNRRMKYKKDQKAK 240



>gi|123268|sp|P14651|HXB3_HUMAN   Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7)
          Length = 431

 Score =  106 bits (264), Expect = 2e-23
 Identities = 51/84 (60%), Positives = 64/84 (76%), Gaps = 9/84 (10%)

Query: 147 GSGGG---------SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVK 197
           G GGG         S+R RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A LL+L+ERQ+K
Sbjct: 174 GGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIK 233

Query: 198 VWFQNRRMKHKRQTQCKENQNSEG 221
           +WFQNRRMK+K+  + K   +S G
Sbjct: 234 IWFQNRRMKYKKDQKAKGLASSSG 257



>gi|6016293|sp|O43365|HXA3_HUMAN   Homeobox protein Hox-A3 (Hox-1E)
          Length = 443

 Score =  105 bits (261), Expect = 3e-23
 Identities = 53/103 (51%), Positives = 67/103 (65%), Gaps = 5/103 (4%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGG-----GSRRLRTAYTNTQLLELEKEFHFNKYLC 178
           ++ +   N   K     S E   G         S+R RTAYT+ QL+ELEKEFHFN+YLC
Sbjct: 158 WMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLC 217

Query: 179 RPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 221
           RPRRVE+A LL+LTERQ+K+WFQNRRMK+K+  + K    S G
Sbjct: 218 RPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSG 260



>gi|1708540|sp|P52945|IPF1_HUMAN   Insulin promoter factor-1 (IPF-1) (Pancreas/duodenum homeobox-1)
           (PDX-1) (Islet/duodenum homeobox-1) (IDX-1)
           (Somatostatin transactivating factor-1) (STF-1) (Insulin
           upstream factor-1) (IUF-1) (Glucose-sensitive factor)
           (GSF)
          Length = 283

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 42/63 (66%), Positives = 52/63 (82%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           ++R RTAYT  QLLELEKEF FNKY+ RPRRVE+A +L+LTER +K+WFQNRRMK K++ 
Sbjct: 146 NKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEE 205

Query: 212 QCK 214
             K
Sbjct: 206 DKK 208



>gi|6166217|sp|Q00056|HXA4_HUMAN   Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4)
          Length = 320

 Score = 90.9 bits (224), Expect = 7e-19
 Identities = 43/62 (69%), Positives = 51/62 (82%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +GG  +R RTAYT  Q+LELEKEFHFN+YL R RR+EIA  L L+ERQVK+WFQNRRMK 
Sbjct: 211 NGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKW 270

Query: 208 KR 209
           K+
Sbjct: 271 KK 272



>gi|20141491|sp|P09016|HXD4_HUMAN   Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13)
          Length = 255

 Score = 90.5 bits (223), Expect = 9e-19
 Identities = 42/62 (67%), Positives = 51/62 (82%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +GG  +R RTAYT  Q+LELEKEFHFN+YL R RR+EIA  L L+ERQ+K+WFQNRRMK 
Sbjct: 150 TGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKW 209

Query: 208 KR 209
           K+
Sbjct: 210 KK 211



>gi|400000|sp|P09067|HXB5_HUMAN   Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1)
          Length = 269

 Score = 90.5 bits (223), Expect = 9e-19
 Identities = 43/69 (62%), Positives = 52/69 (75%)

Query: 146 DGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRM 205
           D +G   +R RTAYT  Q LELEKEFHFN+YL R RR+EIA  L L+ERQ+K+WFQNRRM
Sbjct: 188 DMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRM 247

Query: 206 KHKRQTQCK 214
           K K+  + K
Sbjct: 248 KWKKDNKLK 256



>gi|547692|sp|P17483|HXB4_HUMAN   Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6)
          Length = 251

 Score = 89.7 bits (221), Expect = 1e-18
 Identities = 42/62 (67%), Positives = 51/62 (82%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +GG  +R RTAYT  Q+LELEKEFH+N+YL R RRVEIA  L L+ERQ+K+WFQNRRMK 
Sbjct: 158 AGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKW 217

Query: 208 KR 209
           K+
Sbjct: 218 KK 219



>gi|52788238|sp|P20719|HXA5_HUMAN   Homeobox protein Hox-A5 (Hox-1C)
          Length = 270

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 50/107 (46%), Positives = 67/107 (62%), Gaps = 5/107 (4%)

Query: 113 EAVQAAREHSLYLNQPAPNQSDKDKK---KESLEIADGSGGG--SRRLRTAYTNTQLLEL 167
           E   A+ E +   ++P+P    + +       L I+  + GG   +R RTAYT  Q LEL
Sbjct: 151 EDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLEL 210

Query: 168 EKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 214
           EKEFHFN+YL R RR+EIA  L L+ERQ+K+WFQNRRMK K+  + K
Sbjct: 211 EKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK 257



>gi|20138327|sp|Q9BZM3|GSH2_HUMAN   Homeobox protein GSH-2
          Length = 304

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 42/72 (58%), Positives = 58/72 (80%), Gaps = 1/72 (1%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           +R+RTA+T+TQLLELE+EF  N YL R RR+EIA  L+L+E+QVK+WFQNRR+KHK++ +
Sbjct: 203 KRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 262

Query: 213 CKENQNSEGKCK 224
             + +NS   CK
Sbjct: 263 GTQ-RNSHAGCK 273



>gi|123271|sp|P14653|HXB1_HUMAN   Homeobox protein Hox-B1 (Hox-2I)
          Length = 301

 Score = 88.6 bits (218), Expect = 3e-18
 Identities = 43/76 (56%), Positives = 54/76 (71%)

Query: 135 KDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTER 194
           K    ++ ++++   G    LRT +T  QL ELEKEFHFNKYL R RRVEIAA L+L E 
Sbjct: 186 KRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNET 245

Query: 195 QVKVWFQNRRMKHKRQ 210
           QVK+WFQNRRMK K++
Sbjct: 246 QVKIWFQNRRMKQKKR 261



>gi|27923786|sp|Q9H4S2|GSHI_HUMAN   Homeobox protein GSH-1
          Length = 264

 Score = 87.8 bits (216), Expect = 6e-18
 Identities = 40/70 (57%), Positives = 56/70 (80%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           S+R+RTA+T+TQLLELE+EF  N YL R RR+EIA  L+L+E+QVK+WFQNRR+KHK++ 
Sbjct: 147 SKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEG 206

Query: 212 QCKENQNSEG 221
           +   ++   G
Sbjct: 207 KGSNHRGGGG 216



>gi|17378385|sp|P31267|HXA6_HUMAN   Homeobox protein Hox-A6 (Hox-1B)
          Length = 233

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 42/74 (56%), Positives = 51/74 (68%)

Query: 149 GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           G   RR R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK K
Sbjct: 152 GSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWK 211

Query: 209 RQTQCKENQNSEGK 222
           ++ +   +    G+
Sbjct: 212 KENKLINSTQPSGE 225



>gi|123279|sp|P09017|HXC4_HUMAN   Homeobox protein Hox-C4 (Hox-3E) (CP19)
          Length = 264

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 40/62 (64%), Positives = 50/62 (80%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +GG  +R R AYT  Q+LELEKEFH+N+YL R RR+EIA  L L+ERQ+K+WFQNRRMK 
Sbjct: 152 NGGEPKRSRAAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKW 211

Query: 208 KR 209
           K+
Sbjct: 212 KK 213



>gi|45644931|sp|P50219|HLXB9_HUMAN   Homeobox protein HB9
          Length = 403

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 43/73 (58%), Positives = 51/73 (69%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G  RR RTA+T+ QLLELE +F  NKYL RP+R E+A  L LTE QVK+WFQNRRMK KR
Sbjct: 241 GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKR 300

Query: 210 QTQCKENQNSEGK 222
             + KE    E +
Sbjct: 301 SKKAKEQAAQEAE 313



>gi|232262|sp|Q00444|HXC5_HUMAN   Homeobox protein Hox-C5 (Hox-3D) (CP11)
          Length = 222

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 40/65 (61%), Positives = 50/65 (76%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           +R RT+YT  Q LELEKEFHFN+YL R RR+EIA  L L ERQ+K+WFQNRRMK K+ ++
Sbjct: 156 KRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSK 215

Query: 213 CKENQ 217
            K  +
Sbjct: 216 MKSKE 220



>gi|20141493|sp|P09630|HXC6_HUMAN   Homeobox protein Hox-C6 (Hox-3C) (HHO.C8) (CP25)
          Length = 235

 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 42/75 (56%), Positives = 51/75 (68%)

Query: 147 GSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 206
           G G   RR R  Y+  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK
Sbjct: 136 GYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 195

Query: 207 HKRQTQCKENQNSEG 221
            K+++      +  G
Sbjct: 196 WKKESNLTSTLSGGG 210



>gi|13124738|sp|P17509|HXB6_HUMAN   Homeobox protein Hox-B6 (Hox-2B) (Hox-2.2) (HU-2)
          Length = 224

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 40/64 (62%), Positives = 49/64 (76%)

Query: 149 GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           G   RR R  YT  Q LELEKEFH+N+YL R RR+EIA  L LTERQ+K+WFQNRRMK K
Sbjct: 143 GPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 202

Query: 209 RQTQ 212
           ++++
Sbjct: 203 KESK 206



>gi|3915721|sp|P31268|HXA7_HUMAN   Homeobox protein Hox-A7 (Hox-1A) (Hox 1.1)
          Length = 230

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 41/63 (65%), Positives = 48/63 (76%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           SG   +R R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK 
Sbjct: 126 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 185

Query: 208 KRQ 210
           K++
Sbjct: 186 KKE 188



>gi|6166216|sp|P49639|HXA1_HUMAN   Homeobox protein Hox-A1 (Hox-1F)
          Length = 335

 Score = 85.1 bits (209), Expect = 4e-17
 Identities = 41/61 (67%), Positives = 46/61 (75%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G    +RT +T  QL ELEKEFHFNKYL R RRVEIAA L L E QVK+WFQNRRMK K+
Sbjct: 227 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 286

Query: 210 Q 210
           +
Sbjct: 287 R 287



>gi|123255|sp|P09629|HXB7_HUMAN   Homeobox protein Hox-B7 (Hox-2C) (HHO.C1)
          Length = 217

 Score = 85.1 bits (209), Expect = 4e-17
 Identities = 46/88 (52%), Positives = 55/88 (62%), Gaps = 4/88 (4%)

Query: 129 APNQSDKDKKKES----LEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVE 184
           A  Q D D   ES          SG   +R R  YT  Q LELEKEFH+N+YL R RR+E
Sbjct: 110 AKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIE 169

Query: 185 IAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           IA  L LTERQ+K+WFQNRRMK K++ +
Sbjct: 170 IAHTLCLTERQIKIWFQNRRMKWKKENK 197



>gi|17378648|sp|Q9GZZ0|HXD1_HUMAN   Homeobox protein Hox-D1
          Length = 328

 Score = 82.4 bits (202), Expect = 2e-16
 Identities = 43/80 (53%), Positives = 52/80 (65%), Gaps = 5/80 (6%)

Query: 131 NQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLD 190
           N S K K  E      G+   S  +RT ++  QL ELEKEFHFNKYL R RR+EIA  L 
Sbjct: 213 NASKKGKLAEY-----GAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLH 267

Query: 191 LTERQVKVWFQNRRMKHKRQ 210
           L + QVK+WFQNRRMK K++
Sbjct: 268 LNDTQVKIWFQNRRMKQKKR 287



>gi|13124743|sp|P31260|HXA10_HUMAN   Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL)
          Length = 393

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 48/101 (47%), Positives = 63/101 (62%), Gaps = 10/101 (9%)

Query: 128 PAPNQSDK-DKKKESLEIADGSGGGS-------RRLRTAYTNTQLLELEKEFHFNKYLCR 179
           PAP++S K   +K+SL  + G    +       R+ R  YT  Q LELEKEF FN YL R
Sbjct: 287 PAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTR 346

Query: 180 PRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
            RR+EI+  + LT+RQVK+WFQNRRMK K+    +EN+  E
Sbjct: 347 ERRLEISRSVHLTDRQVKIWFQNRRMKLKKMN--RENRIRE 385



>gi|1345720|sp|P47902|CDX1_HUMAN   Homeobox protein CDX-1 (Caudal-type homeobox protein 1)
          Length = 265

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 41/80 (51%), Positives = 55/80 (68%), Gaps = 6/80 (7%)

Query: 144 IADGSGGGSRRLRT------AYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVK 197
           +A G GGGS + RT       YT+ Q LELEKEFH+++Y+   R+ E+AA L LTERQVK
Sbjct: 140 VAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVK 199

Query: 198 VWFQNRRMKHKRQTQCKENQ 217
           +WFQNRR K ++  + K+ Q
Sbjct: 200 IWFQNRRAKERKVNKKKQQQ 219



>gi|123286|sp|P28356|HXD9_HUMAN   Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2)
          Length = 342

 Score = 80.9 bits (198), Expect = 7e-16
 Identities = 39/63 (61%), Positives = 48/63 (76%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           +R+ R  YT  Q LELEKEF FN YL R RR E+A +L+LTERQVK+WFQNRRMK K+ +
Sbjct: 275 TRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMS 334

Query: 212 QCK 214
           + K
Sbjct: 335 KEK 337



>gi|20141537|sp|P31274|HXC9_HUMAN   Homeobox protein Hox-C9 (Hox-3B)
          Length = 260

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 39/66 (59%), Positives = 49/66 (74%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           +R+ R  YT  Q LELEKEF FN YL R RR E+A +L+LTERQVK+WFQNRRMK K+  
Sbjct: 192 TRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMN 251

Query: 212 QCKENQ 217
           + K ++
Sbjct: 252 KEKTDK 257



>gi|6166219|sp|P31269|HXA9_HUMAN   Homeobox protein Hox-A9 (Hox-1G)
          Length = 272

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 39/58 (67%), Positives = 45/58 (77%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           +R+ R  YT  Q LELEKEF FN YL R RR E+A LL+LTERQVK+WFQNRRMK K+
Sbjct: 206 TRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK 263



>gi|20141507|sp|P17482|HXB9_HUMAN   Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5)
          Length = 250

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 46/101 (45%), Positives = 61/101 (60%), Gaps = 1/101 (0%)

Query: 113 EAVQAAREHSLYLNQPAPNQSDKDKKKESLEIADG-SGGGSRRLRTAYTNTQLLELEKEF 171
           EAV + +      N+      DK++  ++   A+      SR+ R  YT  Q LELEKEF
Sbjct: 145 EAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEF 204

Query: 172 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
            FN YL R RR E+A LL+L+ERQVK+WFQNRRMK K+  +
Sbjct: 205 LFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245



>gi|20141612|sp|Q9NYD6|HXC10_HUMAN   Homeobox protein Hox-C10
          Length = 342

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 45/97 (46%), Positives = 63/97 (64%), Gaps = 8/97 (8%)

Query: 129 APNQSDKDKKKESLEIADGSGG-----GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 183
           +P+ SD + K+E ++  + +G        R+ R  YT  Q LELEKEF FN YL R RR+
Sbjct: 241 SPDTSDNEAKEE-IKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRL 299

Query: 184 EIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
           EI+  ++LT+RQVK+WFQNRRMK K+    +EN+  E
Sbjct: 300 EISKTINLTDRQVKIWFQNRRMKLKKMN--RENRIRE 334



>gi|20141506|sp|P17481|HXB8_HUMAN   Homeobox protein Hox-B8 (Hox-2D) (Hox-2.4)
          Length = 243

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 40/77 (51%), Positives = 52/77 (67%), Gaps = 2/77 (2%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +  G RR R  Y+  Q LELEKEF FN YL R RR+E++  L LTERQVK+WFQNRRMK 
Sbjct: 142 AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKW 201

Query: 208 KRQTQCKENQNSEGKCK 224
           K++    +++    KC+
Sbjct: 202 KKEN--NKDKFPSSKCE 216



>gi|1709078|sp|P50221|MEOX1_HUMAN   Homeobox protein MOX-1 (Mesenchyme homeobox 1)
          Length = 254

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 52/126 (41%), Positives = 68/126 (53%), Gaps = 13/126 (10%)

Query: 84  LGIRSIGLLFPTTEPGSKHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQSDKDKKKESLE 143
           +G  S+GL+  T  PG  +          E   + R       + + NQ ++ K + S +
Sbjct: 116 MGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRR-----KESSDNQENRGKPEGSSK 170

Query: 144 IADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNR 203
                   +R+ RTA+T  QL ELE EF  + YL R RR EIA  LDL+ERQVKVWFQNR
Sbjct: 171 --------ARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNR 222

Query: 204 RMKHKR 209
           RMK KR
Sbjct: 223 RMKWKR 228



>gi|12231013|sp|Q03828|EVX2_HUMAN   Homeobox even-skipped homolog protein 2 (EVX-2)
          Length = 476

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 40/67 (59%), Positives = 48/67 (71%), Gaps = 3/67 (4%)

Query: 147 GSGGGS---RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNR 203
           GSG G+   RR RTA+T  Q+  LEKEF+   Y+ RPRR E+AA L+L E  +KVWFQNR
Sbjct: 180 GSGSGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNR 239

Query: 204 RMKHKRQ 210
           RMK KRQ
Sbjct: 240 RMKDKRQ 246



>gi|13124737|sp|P13378|HXD8_HUMAN   Homeobox protein Hox-D8 (Hox-4E) (Hox-5.4)
          Length = 290

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 38/60 (63%), Positives = 45/60 (75%)

Query: 151 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           G RR R  Y+  Q LELEKEF FN YL R RR+E++  L LTERQVK+WFQNRRMK K++
Sbjct: 196 GRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKE 255



>gi|12230077|sp|Q14549|GBX1_HUMAN   Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox
           protein 1)
          Length = 139

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 40/61 (65%), Positives = 45/61 (73%)

Query: 149 GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           GG SRR RTA+T+ QLLELEKEFH  KYL    R +IA  L L+E QVK+WFQNRR K K
Sbjct: 34  GGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK 93

Query: 209 R 209
           R
Sbjct: 94  R 94



>gi|1352398|sp|P49640|EVX1_HUMAN   Homeobox even-skipped homolog protein 1 (EVX-1)
          Length = 407

 Score = 78.2 bits (191), Expect = 4e-15
 Identities = 41/77 (53%), Positives = 48/77 (62%), Gaps = 13/77 (16%)

Query: 147 GSGGGS-------------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTE 193
           GSGGG              RR RTA+T  Q+  LEKEF+   Y+ RPRR E+AA L+L E
Sbjct: 165 GSGGGGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPE 224

Query: 194 RQVKVWFQNRRMKHKRQ 210
             +KVWFQNRRMK KRQ
Sbjct: 225 TTIKVWFQNRRMKDKRQ 241



>gi|1709079|sp|P50222|MEOX2_HUMAN   Homeobox protein MOX-2 (Mesenchyme homeobox 2) (Growth
           arrest-specific homeobox)
          Length = 303

 Score = 77.8 bits (190), Expect = 6e-15
 Identities = 44/86 (51%), Positives = 54/86 (62%), Gaps = 5/86 (5%)

Query: 129 APNQSDKDKKKESLEIADGS-----GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 183
           A  +S   +K +S +  +G+         R+ RTA+T  Q+ ELE EF  + YL R RR 
Sbjct: 158 AEKRSGGKRKSDSSDSQEGNYKSEVNSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRY 217

Query: 184 EIAALLDLTERQVKVWFQNRRMKHKR 209
           EIA  LDLTERQVKVWFQNRRMK KR
Sbjct: 218 EIAVNLDLTERQVKVWFQNRRMKWKR 243



>gi|123289|sp|P28358|HXD10_HUMAN   Homeobox protein Hox-D10 (Hox-4D) (Hox-4E)
          Length = 340

 Score = 77.4 bits (189), Expect = 8e-15
 Identities = 44/96 (45%), Positives = 59/96 (61%), Gaps = 6/96 (6%)

Query: 129 APNQSDKDKKKESLEIADGSGG----GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVE 184
           +P   +K+ K+E       S        R+ R  YT  Q LELEKEF FN YL R RR+E
Sbjct: 239 SPEVQEKESKEEIKSDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLE 298

Query: 185 IAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
           I+  ++LT+RQVK+WFQNRRMK K+ +  +EN+  E
Sbjct: 299 ISKSVNLTDRQVKIWFQNRRMKLKKMS--RENRIRE 332



>gi|13124745|sp|P31273|HXC8_HUMAN   Homeobox protein Hox-C8 (Hox-3A)
          Length = 242

 Score = 77.0 bits (188), Expect = 1e-14
 Identities = 37/60 (61%), Positives = 44/60 (73%)

Query: 151 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           G R  R  Y+  Q LELEKEF FN YL R RR+E++  L LTERQVK+WFQNRRMK K++
Sbjct: 148 GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKE 207



>gi|13124744|sp|P31270|HXA11_HUMAN   Homeobox protein Hox-A11 (Hox-1I)
          Length = 313

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 38/94 (40%), Positives = 60/94 (63%), Gaps = 1/94 (1%)

Query: 117 AAREHSLYLNQPAPNQSDKDKKKESLEIADGSGGG-SRRLRTAYTNTQLLELEKEFHFNK 175
           AA E      +P  + S +     + + A GS G  +R+ R  YT  Q+ ELE+EF F+ 
Sbjct: 205 AAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSV 264

Query: 176 YLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           Y+ + +R++++ +L+LT+RQVK+WFQNRRMK K+
Sbjct: 265 YINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 298



>gi|12644308|sp|P52951|GBX2_HUMAN   Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox
           protein 2)
          Length = 348

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 39/62 (62%), Positives = 45/62 (72%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           S G +RR RTA+T+ QLLELEKEFH  KYL    R +IA  L L+E QVK+WFQNRR K 
Sbjct: 243 STGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKW 302

Query: 208 KR 209
           KR
Sbjct: 303 KR 304



>gi|2506529|sp|Q07687|DLX2_HUMAN   Homeobox protein DLX-2
          Length = 328

 Score = 73.9 bits (180), Expect = 8e-14
 Identities = 36/90 (40%), Positives = 54/90 (60%)

Query: 126 NQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEI 185
           + PA N+ +K+  +  + I +G     R+ RT Y++ QL  L++ F   +YL  P R E+
Sbjct: 126 SSPANNEPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAEL 185

Query: 186 AALLDLTERQVKVWFQNRRMKHKRQTQCKE 215
           AA L LT+ QVK+WFQNRR K K+  +  E
Sbjct: 186 AASLGLTQTQVKIWFQNRRSKFKKMWKSGE 215



>gi|3913487|sp|O60479|DLX3_HUMAN   Homeobox protein DLX-3
          Length = 287

 Score = 73.2 bits (178), Expect = 1e-13
 Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 3/94 (3%)

Query: 119 REHSLYLNQPAPNQ---SDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNK 175
           R++  Y  QP P Q   S K++ +  + + +G     R+ RT Y++ QL  L++ F   +
Sbjct: 93  RQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQ 152

Query: 176 YLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           YL  P R E+AA L LT+ QVK+WFQNRR K K+
Sbjct: 153 YLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK 186



>gi|20141282|sp|Q99626|CDX2_HUMAN   Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3)
          Length = 313

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 33/67 (49%), Positives = 47/67 (70%)

Query: 154 RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQC 213
           + R  YT+ Q LELEKEFH+++Y+   R+ E+AA L L+ERQVK+WFQNRR K ++  + 
Sbjct: 188 KYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKK 247

Query: 214 KENQNSE 220
           K  Q  +
Sbjct: 248 KLQQQQQ 254



>gi|12644203|sp|P31277|HXD11_HUMAN   Homeobox protein Hox-D11 (Hox-4F)
          Length = 338

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 31/58 (53%), Positives = 46/58 (79%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           SR+ R  YT  Q+ ELE+EF FN Y+ + +R++++ +L+LT+RQVK+WFQNRRMK K+
Sbjct: 266 SRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323



>gi|3287858|sp|O43248|HXC11_HUMAN   Homeobox protein Hox-C11
          Length = 304

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 34/82 (41%), Positives = 55/82 (67%)

Query: 128 PAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAA 187
           P+ + S     KE  + A  +   +R+ R  Y+  Q+ ELE+EF FN Y+ + +R++++ 
Sbjct: 208 PSSSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSR 267

Query: 188 LLDLTERQVKVWFQNRRMKHKR 209
           +L+LT+RQVK+WFQNRRMK K+
Sbjct: 268 MLNLTDRQVKIWFQNRRMKEKK 289



>gi|3023467|sp|O14627|CDX4_HUMAN   Homeobox protein CDX-4 (Caudal-type homeobox protein 4)
          Length = 284

 Score = 70.9 bits (172), Expect = 7e-13
 Identities = 36/70 (51%), Positives = 48/70 (68%), Gaps = 2/70 (2%)

Query: 154 RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQC 213
           + R  YT+ Q LELEKEFH N+Y+   R+ E+A  L L+ERQVK+WFQNRR K ++  + 
Sbjct: 175 KYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKK 234

Query: 214 KENQ--NSEG 221
           K +Q  NS G
Sbjct: 235 KISQFENSGG 244



>gi|57015304|sp|Q04741|EMX1_HUMAN   Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty
           spiracles-like protein 1)
          Length = 257

 Score = 70.9 bits (172), Expect = 7e-13
 Identities = 36/72 (50%), Positives = 48/72 (66%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           +R+RTA++ +QLL LE+ F  N Y+    R ++A  L L+E QVKVWFQNRR K+KRQ  
Sbjct: 160 KRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKL 219

Query: 213 CKENQNSEGKCK 224
            +E   SE K K
Sbjct: 220 EEEGPESEQKKK 231



>gi|19862512|sp|Q04743|EMX2_HUMAN   Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty
           spiracles-like protein 2)
          Length = 252

 Score = 70.5 bits (171), Expect = 9e-13
 Identities = 39/89 (43%), Positives = 52/89 (58%)

Query: 136 DKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQ 195
           D   ES  + +      +R+RTA++ +QLL LE  F  N Y+    R ++A  L LTE Q
Sbjct: 138 DTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQ 197

Query: 196 VKVWFQNRRMKHKRQTQCKENQNSEGKCK 224
           VKVWFQNRR K KRQ   +E  +S+ K K
Sbjct: 198 VKVWFQNRRTKFKRQKLEEEGSDSQQKKK 226



>gi|17377578|sp|Q99801|NKX31_HUMAN   Homeobox protein Nkx-3.1
          Length = 234

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 32/63 (50%), Positives = 43/63 (68%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           +R R A+++TQ++ELE++F   KYL  P R  +A  L LTE QVK+WFQNRR K KR+  
Sbjct: 125 KRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQL 184

Query: 213 CKE 215
             E
Sbjct: 185 SSE 187



>gi|12644329|sp|P56178|DLX5_HUMAN   Homeobox protein DLX-5
          Length = 289

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 33/81 (40%), Positives = 50/81 (61%)

Query: 129 APNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAAL 188
           A NQ +K+  +  + + +G     R+ RT Y++ QL  L++ F   +YL  P R E+AA 
Sbjct: 114 ATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAAS 173

Query: 189 LDLTERQVKVWFQNRRMKHKR 209
           L LT+ QVK+WFQN+R K K+
Sbjct: 174 LGLTQTQVKIWFQNKRSKIKK 194



>gi|29336920|sp|Q9BZE3|BARH1_HUMAN   BarH-like 1 homeobox protein (FKSG31 protein)
          Length = 327

 Score = 68.2 bits (165), Expect = 5e-12
 Identities = 33/59 (55%), Positives = 43/59 (72%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           R+ RTA+T+ QL +LE+ F   KYL    R+E+AA L+LT+ QVK W+QNRR K KRQT
Sbjct: 179 RKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQT 237



>gi|12644227|sp|P35452|HXD12_HUMAN   Homeobox protein Hox-D12 (Hox-4H)
          Length = 275

 Score = 67.8 bits (164), Expect = 6e-12
 Identities = 31/63 (49%), Positives = 45/63 (71%)

Query: 147 GSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 206
           G  G +R+ R  YT  Q+ ELE EF  N+++ R +R E++  L+L+++QVK+WFQNRRMK
Sbjct: 202 GGPGEARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMK 261

Query: 207 HKR 209
            KR
Sbjct: 262 KKR 264



>gi|38605720|sp|P56177|DLX1_HUMAN   Homeobox protein DLX-1
          Length = 255

 Score = 67.8 bits (164), Expect = 6e-12
 Identities = 43/118 (36%), Positives = 58/118 (49%), Gaps = 2/118 (1%)

Query: 93  FPTTEPGSKHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQSDKDKKKESLEIA-DGSGGG 151
           +P     S H   P I  V     +A      L  P  + S+K    E  E+  +G G  
Sbjct: 69  YPYVNSVSSHASSPYISSVQSYPGSASLAQSRLEDPGAD-SEKSTVVEGGEVRFNGKGKK 127

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
            R+ RT Y + QL  L + F   +YL  P R E+AA L LT+ QVK+WFQN+R K K+
Sbjct: 128 IRKPRTIYCSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 185



>gi|6016210|sp|P78367|NK32_HUMAN   Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1)
          Length = 333

 Score = 67.4 bits (163), Expect = 8e-12
 Identities = 30/58 (51%), Positives = 42/58 (72%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           +R R A+++ Q+ ELE+ F+  +YL  P R ++AA L LTE QVK+WFQNRR K KR+
Sbjct: 207 KRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR 264



>gi|2833256|sp|Q14774|HLX1_HUMAN   Homeobox protein HLX1 (Homeobox protein HB24)
          Length = 488

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 31/67 (46%), Positives = 46/67 (68%), Gaps = 2/67 (2%)

Query: 156 RTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK--HKRQTQC 213
           R  ++N Q   LEK F   KY+ +P R ++AA+L LT+ QVKVWFQNRRMK  H ++ Q 
Sbjct: 280 RAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQA 339

Query: 214 KENQNSE 220
           +++++ E
Sbjct: 340 QKDKDKE 346



>gi|399982|sp|P31314|TLX1_HUMAN   T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (TCL-3
           proto-oncogene)
          Length = 330

 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 30/59 (50%), Positives = 39/59 (66%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           ++ RT++T  Q+ ELEK FH  KYL    R  +A  L +T+ QVK WFQNRR K +RQT
Sbjct: 202 KKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQT 260



>gi|20141538|sp|P31275|HXC12_HUMAN   Homeobox protein Hox-C12 (Hox-3F)
          Length = 282

 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 31/58 (53%), Positives = 43/58 (74%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           SR+ R  Y+  QL ELE EF  N+++ R RR E++  L+L+++QVK+WFQNRRMK KR
Sbjct: 214 SRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271



>gi|13431329|sp|Q9UMQ3|BARX2_HUMAN   Homeobox protein BarH-like 2
          Length = 254

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 31/57 (54%), Positives = 40/57 (70%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           RR RT +T  QL+ LEK+F   KYL  P R+++A  L LT+ QVK W+QNRRMK K+
Sbjct: 109 RRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 165



>gi|47117915|sp|Q9NY43|BARH2_HUMAN   BarH-like 2 homeobox protein
          Length = 387

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 31/59 (52%), Positives = 43/59 (72%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           R+ RTA+++ QL +LE+ F   KYL    R+++AA L+LT+ QVK W+QNRR K KRQT
Sbjct: 233 RKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQT 291



>gi|23831508|sp|O43711|TLX3_HUMAN   T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
          Length = 291

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 31/70 (44%), Positives = 45/70 (64%), Gaps = 2/70 (2%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           ++ RT+++  Q+ ELEK FH  KYL    R  +A  L +T+ QVK WFQNRR K +RQT 
Sbjct: 167 KKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQT- 225

Query: 213 CKENQNSEGK 222
             E + ++G+
Sbjct: 226 -AEEREADGQ 234



>gi|12644330|sp|P56179|DLX6_HUMAN   Homeobox protein DLX-6
          Length = 175

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 43/102 (42%), Positives = 58/102 (56%), Gaps = 12/102 (11%)

Query: 120 EHSLYL----NQPAPNQS---DKDKKK----ESLEIA-DGSGGGSRRLRTAYTNTQLLEL 167
           +HS YL    N  A  Q+   D D++K    E+ EI  +G G   R+ RT Y++ QL  L
Sbjct: 5   QHSPYLQSYHNSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQLQAL 64

Query: 168 EKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
              F   +YL  P R E+AA L LT+ QVK+WFQN+R K K+
Sbjct: 65  NHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 106



>gi|27923817|sp|Q9H2Z4|NK24_HUMAN   Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox
           protein NK-2 homolog D)
          Length = 353

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 33/85 (38%), Positives = 46/85 (54%)

Query: 133 SDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLT 192
           +D  K    L  A  +    R+ R  ++  Q+ ELE+ F   KYL  P R  +A+++ LT
Sbjct: 170 ADAAKSLGPLHAAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLT 229

Query: 193 ERQVKVWFQNRRMKHKRQTQCKENQ 217
             QVK+WFQN R K KRQ + K  Q
Sbjct: 230 PTQVKIWFQNHRYKMKRQAKDKAAQ 254



>gi|547658|sp|Q03014|HHEX_HUMAN   Homeobox protein PRH (Hematopoietically expressed homeobox)
           (Homeobox protein HEX)
          Length = 270

 Score = 64.3 bits (155), Expect = 7e-11
 Identities = 33/64 (51%), Positives = 41/64 (64%), Gaps = 2/64 (3%)

Query: 159 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQN 218
           ++N Q +ELEK+F   KYL  P R  +A +L L+ERQVK WFQNRR K +R  Q  EN  
Sbjct: 144 FSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQ--ENPQ 201

Query: 219 SEGK 222
           S  K
Sbjct: 202 SNKK 205



>gi|14194481|sp|Q9HBU1|BARX1_HUMAN   Homeobox protein BarH-like 1
          Length = 225

 Score = 64.3 bits (155), Expect = 7e-11
 Identities = 30/57 (52%), Positives = 39/57 (68%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           RR RT +T  QL+ LEK F   KYL  P R+++A  L L++ QVK W+QNRRMK K+
Sbjct: 114 RRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 170



>gi|6016205|sp|O95096|NKX22_HUMAN   Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
          Length = 273

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 35/98 (35%), Positives = 47/98 (47%), Gaps = 9/98 (9%)

Query: 121 HSLYLNQPAPNQSDKDKKKESLEIAD---------GSGGGSRRLRTAYTNTQLLELEKEF 171
           H L    P  + S K  +  + E  D         G  G  R+ R  ++  Q  ELE+ F
Sbjct: 88  HGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGGGDAGKKRKRRVLFSKAQTYELERRF 147

Query: 172 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
              +YL  P R  +A+L+ LT  QVK+WFQN R K KR
Sbjct: 148 RQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185



>gi|2828197|sp|P31271|HXA13_HUMAN   Homeobox protein Hox-A13 (Hox-1J)
          Length = 388

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R+ R  YT  QL ELE+E+  NK++ + +R  I+A  +L+ERQV +WFQNRR+K K+
Sbjct: 323 RKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379



>gi|13959687|sp|P35548|MSX2_HUMAN   Homeobox protein MSX-2 (Hox-8)
          Length = 267

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 30/58 (51%), Positives = 41/58 (70%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           +R+ RT +T +QLL LE++F   +YL    R E ++ L+LTE QVK+WFQNRR K KR
Sbjct: 142 NRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199



>gi|14917010|sp|Q05925|HME1_HUMAN   Homeobox protein engrailed-1 (Hu-En-1)
          Length = 392

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 6/91 (6%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 183
           Y ++P+     +  KK+  E  D      +R RTA+T  QL  L+ EF  N+Y+   RR 
Sbjct: 281 YSDRPSSGPRTRKLKKKKNEKED------KRPRTAFTAEQLQRLKAEFQANRYITEQRRQ 334

Query: 184 EIAALLDLTERQVKVWFQNRRMKHKRQTQCK 214
            +A  L L E Q+K+WFQN+R K K+ T  K
Sbjct: 335 TLAQELSLNESQIKIWFQNKRAKIKKATGIK 365



>gi|20141539|sp|P31276|HXC13_HUMAN   Homeobox protein Hox-C13 (Hox-3G)
          Length = 330

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 28/57 (49%), Positives = 41/57 (71%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R+ R  YT  QL ELEKE+  +K++ + +R  I+A  +L+ERQV +WFQNRR+K K+
Sbjct: 261 RKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317



>gi|21903415|sp|P19622|HME2_HUMAN   Homeobox protein engrailed-2 (Hu-En-2)
          Length = 333

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 34/88 (38%), Positives = 49/88 (55%), Gaps = 6/88 (6%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 183
           Y ++P+     +  KK++    D      +R RTA+T  QL  L+ EF  N+YL   RR 
Sbjct: 222 YSDRPSSGPRSRKPKKKNPNKED------KRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQ 275

Query: 184 EIAALLDLTERQVKVWFQNRRMKHKRQT 211
            +A  L L E Q+K+WFQN+R K K+ T
Sbjct: 276 SLAQELSLNESQIKIWFQNKRAKIKKAT 303



>gi|1708211|sp|P52952|NK25_HUMAN   Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E)
           (Cardiac-specific homeobox) (Homeobox protein CSX)
          Length = 324

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 29/60 (48%), Positives = 40/60 (66%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           R+ R  ++  Q+ ELE+ F   +YL  P R ++A++L LT  QVK+WFQNRR K KRQ Q
Sbjct: 139 RKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQ 198



>gi|3915680|sp|Q92988|DLX4_HUMAN   Homeobox protein DLX-4 (DLX-7) (DLX-8)
          Length = 347

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 31/70 (44%), Positives = 45/70 (64%), Gaps = 4/70 (5%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           R+ RT Y++ QL  L + F   +YL  P R ++AA L LT+ QVK+WFQN+R K+K+  +
Sbjct: 226 RKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK 285

Query: 213 CKENQNSEGK 222
               QNS G+
Sbjct: 286 ----QNSGGQ 291



>gi|23503066|sp|P28360|MSX1_HUMAN   Homeobox protein MSX-1 (Hox-7)
          Length = 297

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/58 (51%), Positives = 39/58 (67%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           +R+ RT +T  QLL LE++F   +YL    R E ++ L LTE QVK+WFQNRR K KR
Sbjct: 166 NRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 223



>gi|27923815|sp|Q8TAU0|NKX23_HUMAN   Homeobox protein Nkx-2.3 (Homeobox protein NKX-2.3) (Homeobox
           protein NK-2 homolog C)
          Length = 364

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 30/62 (48%), Positives = 39/62 (62%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           R+ R  ++  Q+ ELE+ F   +YL  P R  +A+ L LT  QVK+WFQNRR K KRQ Q
Sbjct: 149 RKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQ 208

Query: 213 CK 214
            K
Sbjct: 209 DK 210



>gi|1730095|sp|P52954|LBX1_HUMAN   Transcription factor LBX1
          Length = 280

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 32/60 (53%), Positives = 39/60 (65%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           R+ RTA+TN Q+ ELEK F + KYL    R +IA  L LT  QV  WFQNRR K KR+ +
Sbjct: 125 RKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRELE 184



>gi|2851475|sp|P35453|HXD13_HUMAN   Homeobox protein Hox-D13 (Hox-4I)
          Length = 335

 Score = 62.0 bits (149), Expect = 3e-10
 Identities = 28/57 (49%), Positives = 40/57 (70%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R+ R  YT  QL ELE E+  NK++ + +R  I+A  +L+ERQV +WFQNRR+K K+
Sbjct: 269 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325



>gi|1174819|sp|P43699|TITF1_HUMAN   Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1)
           (Homeobox protein Nkx-2.1) (Homeobox protein NK-2
           homolog A)
          Length = 371

 Score = 62.0 bits (149), Expect = 3e-10
 Identities = 29/65 (44%), Positives = 40/65 (61%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           R+ R  ++  Q+ ELE+ F   KYL  P R  +A+++ LT  QVK+WFQN R K KRQ +
Sbjct: 162 RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAK 221

Query: 213 CKENQ 217
            K  Q
Sbjct: 222 DKAAQ 226



>gi|20532295|sp|Q9UIW0|VAX2_HUMAN   Ventral anterior homeobox 2
          Length = 290

 Score = 61.2 bits (147), Expect = 6e-10
 Identities = 38/93 (40%), Positives = 50/93 (53%), Gaps = 10/93 (10%)

Query: 127 QPAPNQSD-------KDKKKESLEIADGSG---GGSRRLRTAYTNTQLLELEKEFHFNKY 176
           QP P ++D       +D K    EI    G      +R RT++T  QL  LE EF   +Y
Sbjct: 67  QPGPGEADHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQY 126

Query: 177 LCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           +    R E+A  L+L+E QVKVWFQNRR K K+
Sbjct: 127 VVGRERTELARQLNLSETQVKVWFQNRRTKQKK 159



>gi|6174907|sp|Q99697|PITX2_HUMAN   Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription
           factor) (Solurshin) (ALL1 responsive protein ARP1)
          Length = 317

 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 41/108 (37%), Positives = 57/108 (52%), Gaps = 6/108 (5%)

Query: 116 QAAREHSLYLNQPAPNQSDKDK--KKESLEIADGSGGG-SRRLRTAYTNTQLLELEKEFH 172
           +AA         P  N+ DK +  K E +   D S     RR RT +T+ QL ELE  F 
Sbjct: 46  EAASSKFFPRQHPGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQ 105

Query: 173 FNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
            N+Y     R EIA   +LTE +V+VWF+NRR K +++   + NQ +E
Sbjct: 106 RNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKR---ERNQQAE 150



>gi|20532396|sp|O43763|TLX2_HUMAN   T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1)
           (Neural crest homeobox protein)
          Length = 284

 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 28/59 (47%), Positives = 40/59 (67%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           ++ RT+++ +Q+LELE+ F   KYL    R  +A  L +T+ QVK WFQNRR K +RQT
Sbjct: 158 KKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQT 216



>gi|6016208|sp|O15522|NK28_HUMAN   Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H)
          Length = 239

 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 6/119 (5%)

Query: 94  PTTEPGSKHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQS--DKDKKKESLEIADGSGGG 151
           P  EP    PR P+       + + R H    ++ +   S  D  ++  +   + GS   
Sbjct: 26  PRREP---EPRAPQPDPCAAWLDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAE 82

Query: 152 SRRLRTA-YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
            R+ R   ++  Q LELE+ F   +YL  P R ++A+LL LT  QVK+WFQN R K KR
Sbjct: 83  KRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141



>gi|8134640|sp|O14813|PHX2A_HUMAN   Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A)
           (Aristaless homeobox protein homolog) (ARIX1 homeodomain
           protein)
          Length = 284

 Score = 60.8 bits (146), Expect = 7e-10
 Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 28/130 (21%)

Query: 103 PRCPRIRKVWEAVQAAREHSLYLNQPAPNQSDK-----------DKKKESLEIADGSGGG 151
           P CP +     A+ A R+H     QPAP  +             +K+K+           
Sbjct: 47  PPCPALGSSNCALGALRDH-----QPAPYSAVPYNFFPEPSGLHEKRKQ----------- 90

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
            RR+RT +T+ QL ELE+ F    Y     R E+A  +DLTE +V+VWFQNRR K ++Q 
Sbjct: 91  -RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQE 149

Query: 212 QCKENQNSEG 221
           +    + + G
Sbjct: 150 RAASAKGAAG 159



>gi|50403792|sp|Q92826|HXB13_HUMAN   Homeobox protein Hox-B13
          Length = 284

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 26/57 (45%), Positives = 41/57 (71%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R+ R  Y+  QL ELE+E+  NK++ + +R +I+A   L+ERQ+ +WFQNRR+K K+
Sbjct: 217 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273



>gi|6093723|sp|O75364|PITX3_HUMAN   Pituitary homeobox 3 (Homeobox protein PITX3)
          Length = 302

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 43/132 (32%), Positives = 64/132 (48%), Gaps = 25/132 (18%)

Query: 96  TEPGSKHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQSDKDKKKESLEIADGSG-GGS-- 152
           ++ G+ HP+ P             EH          Q   D +K S  +  GS   GS  
Sbjct: 19  SDAGTPHPQLP-------------EHG------CKGQEHSDSEKASASLPGGSPEDGSLK 59

Query: 153 ---RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
              RR RT +T+ QL ELE  F  N+Y     R EIA   +LTE +V+VWF+NRR K ++
Sbjct: 60  KKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK 119

Query: 210 QTQCKENQNSEG 221
           + + ++ +  +G
Sbjct: 120 RERSQQAELCKG 131



>gi|6016211|sp|P78426|NK61_HUMAN   Homeobox protein Nkx-6.1
          Length = 367

 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 31/76 (40%), Positives = 42/76 (55%), Gaps = 5/76 (6%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G  +  R  ++  Q+  LEK F   KYL  P R  +A  L +TE QVKVWFQNRR K ++
Sbjct: 234 GKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 293

Query: 210 Q-----TQCKENQNSE 220
           +        K+ Q+SE
Sbjct: 294 KHAAEMATAKKKQDSE 309



>gi|8134644|sp|Q99453|PHX2B_HUMAN   Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B)
           (PHOX2B homeodomain protein) (Neuroblastoma Phox)
           (NBPhox)
          Length = 314

 Score = 57.8 bits (138), Expect = 6e-09
 Identities = 29/58 (50%), Positives = 39/58 (67%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR+RT +T+ QL ELE+ F    Y     R E+A  +DLTE +V+VWFQNRR K ++Q
Sbjct: 99  RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQ 156



>gi|48428084|sp|Q8N693|ESX1L_HUMAN   Extraembryonic, spermatogenesis, homeobox 1-like protein
          Length = 406

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 31/57 (54%), Positives = 38/57 (66%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           RR RTA+T  QL ELE  F  ++Y     R  +AA L+LTE +V+VWFQNRR K KR
Sbjct: 140 RRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKR 196



>gi|27923733|sp|Q96QS3|ARX_HUMAN   Homeobox protein ARX (Aristaless-related homeobox)
          Length = 562

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 30/69 (43%), Positives = 41/69 (59%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           RR RT +T+ QL ELE+ F    Y     R E+A  LDLTE +V+VWFQNRR K +++ +
Sbjct: 329 RRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK 388

Query: 213 CKENQNSEG 221
                +  G
Sbjct: 389 AGAQTHPPG 397



>gi|13626112|sp|Q9H161|ALX4_HUMAN   Homeobox protein aristaless-like 4
          Length = 411

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 34/78 (43%), Positives = 45/78 (57%), Gaps = 2/78 (2%)

Query: 142 LEIADGSG--GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 199
           LE AD     G  RR RT +T+ QL ELEK F    Y     R ++A   DLTE +V+VW
Sbjct: 202 LEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVW 261

Query: 200 FQNRRMKHKRQTQCKENQ 217
           FQNRR K +++ +  + Q
Sbjct: 262 FQNRRAKWRKRERFGQMQ 279



>gi|3024482|sp|P78337|PITX1_HUMAN   Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot)
          Length = 314

 Score = 54.7 bits (130), Expect = 5e-08
 Identities = 28/58 (48%), Positives = 38/58 (65%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT +T+ QL ELE  F  N+Y     R EIA   +LTE +V+VWF+NRR K +++
Sbjct: 90  RRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKR 147



>gi|18202099|sp|O60902|SHOX2_HUMAN   Short stature homeobox protein 2 (Paired-related homeobox protein
           SHOT) (Homeobox protein Og12X)
          Length = 331

 Score = 53.9 bits (128), Expect = 9e-08
 Identities = 39/109 (35%), Positives = 58/109 (53%), Gaps = 5/109 (4%)

Query: 114 AVQAAREH-SLYLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFH 172
           A + +RE  S  L + +P   D+ +  + +E    +    RR RT +T  QL ELE+ F 
Sbjct: 101 AAERSREPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFD 160

Query: 173 FNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 221
              Y     R E++  L L+E +V+VWFQNRR K ++Q    ENQ  +G
Sbjct: 161 ETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ----ENQLHKG 205



>gi|17380297|sp|Q9Y2V3|RX_HUMAN   Retinal homeobox protein Rx (Retina and anterior neural fold
           homeobox protein)
          Length = 346

 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 39/118 (33%), Positives = 57/118 (48%), Gaps = 15/118 (12%)

Query: 94  PTTEPGSKHPRCPRIRKVWEAVQA-AREHSLYLNQPAPNQSDKDKKKESLEIADGSGGGS 152
           P  E  +  P CP+  + WEA  +          +   ++ ++ KKK             
Sbjct: 91  PAPEYEAPRPYCPK--EPWEARPSPGLPVGPATGEAKLSEEEQPKKKH------------ 136

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT +T  QL ELE+ F  + Y     R E+A  ++L E +V+VWFQNRR K +RQ
Sbjct: 137 RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQ 194



>gi|3023579|sp|Q15699|CRT1_HUMAN   Cartilage homeoprotein 1 (CART-1)
          Length = 326

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 29/73 (39%), Positives = 43/73 (58%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           S    RR RT +T+ QL ELEK F    Y     R ++A   +LTE +V+VWFQNRR K 
Sbjct: 128 SSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKW 187

Query: 208 KRQTQCKENQNSE 220
           +++ +  + Q ++
Sbjct: 188 RKRERYGQIQQAK 200



>gi|13626107|sp|O95076|ALX3_HUMAN   Homeobox protein aristaless-like 3 (Proline-rich transcription
           factor ALX3)
          Length = 343

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 30/71 (42%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 140 ESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 199
           +S+E+A       RR RT ++  QL ELEK F    Y     R ++A   DLTE +V+VW
Sbjct: 142 DSMELAKNKSK-KRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVW 200

Query: 200 FQNRRMKHKRQ 210
           FQNRR K +++
Sbjct: 201 FQNRRAKWRKR 211



>gi|6831676|sp|O15266|SHOX_HUMAN   Short stature homeobox protein (Short stature homeobox containing
           protein) (Pseudoautosomal homeobox containing osteogenic
           protein)
          Length = 292

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 7/88 (7%)

Query: 137 KKKESLEIADGSGGGS---RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTE 193
           +K+E ++  D  G      RR RT +T  QL ELE+ F    Y     R E++  L L+E
Sbjct: 99  EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158

Query: 194 RQVKVWFQNRRMKHKRQTQCKENQNSEG 221
            +V+VWFQNRR K ++Q    ENQ  +G
Sbjct: 159 ARVQVWFQNRRAKCRKQ----ENQMHKG 182



>gi|3287764|sp|O43186|CRX_HUMAN   Cone-rod homeobox protein
          Length = 299

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 31/74 (41%), Positives = 44/74 (59%), Gaps = 2/74 (2%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK--HKRQ 210
           RR RT +T +QL ELE  F   +Y     R E+A  ++L E +V+VWF+NRR K   +RQ
Sbjct: 40  RRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQ 99

Query: 211 TQCKENQNSEGKCK 224
            Q ++ Q   G+ K
Sbjct: 100 QQKQQQQPPGGQAK 113



>gi|51702790|sp|P63015|PAX6_MOUSE   Paired box protein Pax-6 (Oculorhombin)
 gi|6174889|sp|P26367|PAX6_HUMAN   Paired box protein Pax-6 (Oculorhombin) (Aniridia, type II protein)
          Length = 422

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 126 NQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEI 185
           N  + N  D D+ +  L++        +R RT++T  Q+  LEKEF    Y     R  +
Sbjct: 188 NSISSNGEDSDEAQMRLQLKRKL----QRNRTSFTQEQIEALEKEFERTHYPDVFARERL 243

Query: 186 AALLDLTERQVKVWFQNRRMKHKRQTQCKENQ 217
           AA +DL E +++VWF NRR K +R+ + +  +
Sbjct: 244 AAKIDLPEARIQVWFSNRRAKWRREEKLRNQR 275



>gi|17374365|sp|P58304|CHX10_HUMAN   Homeobox protein CHX10 (Ceh-10 homeodomain containing homolog)
          Length = 361

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 11/139 (7%)

Query: 85  GIRSIGLLFPTTEPGS----------KHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQSD 134
           G+  +GLL P   PG             P+   ++ +  A     + S   +  + + S 
Sbjct: 72  GVGGMGLLGPGGLPGFYTQPTFLEVLSDPQSVHLQPLGRA-SGPLDTSQTASSDSEDVSS 130

Query: 135 KDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTER 194
            D+K     +        RR RT +T+ QL ELEK F+   Y     R  +A   +L E 
Sbjct: 131 SDRKMSKSALNQTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPED 190

Query: 195 QVKVWFQNRRMKHKRQTQC 213
           +++VWFQNRR K +++ +C
Sbjct: 191 RIQVWFQNRRAKWRKREKC 209



>gi|27923801|sp|Q8TE12|LMX1A_HUMAN   LIM homeobox transcription factor 1 alpha (LIM/homeobox protein
           LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1)
          Length = 382

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 15/170 (8%)

Query: 123 LYLNQPAPNQSDKDKKKESL-EIADGSGGGS----------RRLRTAYTNTQLLELEKEF 171
           L L  PA + S K   +ESL + A G+G G+          +R RT  T  Q    +  F
Sbjct: 155 LSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASF 214

Query: 172 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK----RQTQCKENQNSEGKCKXXX 227
             +   CR  R  +AA   L+ R V+VWFQN+R K K    RQ Q +++Q +  +     
Sbjct: 215 EVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQ 274

Query: 228 XXXXXXXXXXXXXXXXQALSVSGALLEREGYTFQQNALSQQQAPNGHNGD 277
                            AL     LL  E   +  +   Q   P    GD
Sbjct: 275 TNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGD 324



>gi|7531125|sp|P56915|GSC_HUMAN   Homeobox protein goosecoid
          Length = 252

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 29/70 (41%), Positives = 43/70 (61%), Gaps = 2/70 (2%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ-- 210
           RR RT +T+ QL  LE  F   KY     R ++A  + L E +V+VWF+NRR K +RQ  
Sbjct: 156 RRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKR 215

Query: 211 TQCKENQNSE 220
           +  +E++N+E
Sbjct: 216 SSSEESENAE 225



>gi|12644475|sp|Q99811|PRRX2_HUMAN   Paired mesoderm homeobox protein 2 (PRX-2) (Paired related homeobox
           protein 2)
          Length = 253

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 10/82 (12%)

Query: 128 PAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAA 187
           P+P +    K+K+            RR RT + ++QL  LE+ F    Y     R E+A 
Sbjct: 90  PSPGRGSAAKRKKK----------QRRNRTTFNSSQLQALERVFERTHYPDAFVREELAR 139

Query: 188 LLDLTERQVKVWFQNRRMKHKR 209
            ++L+E +V+VWFQNRR K +R
Sbjct: 140 RVNLSEARVQVWFQNRRAKFRR 161



>gi|6174916|sp|P54821|PRRX1_HUMAN   Paired mesoderm homeobox protein 1 (PRX-1) (Paired related homeobox
           protein 1) (Homeobox protein PHOX1)
          Length = 245

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 12/79 (15%)

Query: 131 NQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLD 190
           N  +K K+K+            RR RT + ++QL  LE+ F    Y     R ++A  ++
Sbjct: 85  NSEEKKKRKQ------------RRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVN 132

Query: 191 LTERQVKVWFQNRRMKHKR 209
           LTE +V+VWFQNRR K +R
Sbjct: 133 LTEARVQVWFQNRRAKFRR 151



>gi|12230168|sp|Q9UBX0|HESX1_HUMAN   Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf)
          Length = 185

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 26/57 (45%), Positives = 35/57 (61%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           RR RTA+T  Q+  LE  F  N Y     R ++A  L+L E ++++WFQNRR K KR
Sbjct: 109 RRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKR 165



>gi|8247951|sp|P23759|PAX7_HUMAN   Paired box protein Pax-7 (HUP1)
          Length = 520

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 27/58 (46%), Positives = 34/58 (58%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT +T  QL ELEK F    Y     R E+A    LTE +V+VWF NRR + ++Q
Sbjct: 218 RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275



>gi|417427|sp|P32243|OTX2_HUMAN   Homeobox protein OTX2
          Length = 289

 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 27/64 (42%), Positives = 39/64 (60%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           RR RT +T  QL  LE  F   +Y     R E+A  ++L E +V+VWF+NRR K ++Q Q
Sbjct: 39  RRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ 98

Query: 213 CKEN 216
            ++N
Sbjct: 99  QQQN 102



>gi|1172022|sp|P23760|PAX3_HUMAN   Paired box protein Pax-3 (HUP2)
          Length = 479

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 26/58 (44%), Positives = 34/58 (58%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT +T  QL ELE+ F    Y     R E+A    LTE +V+VWF NRR + ++Q
Sbjct: 220 RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ 277



>gi|8247930|sp|O60663|LMX1B_HUMAN   LIM homeobox transcription factor 1 beta (LIM/homeobox protein
           LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2)
          Length = 379

 Score = 47.8 bits (112), Expect = 6e-06
 Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 20/116 (17%)

Query: 125 LNQPAPNQSDKDKKKES---LEIADGSGGGSR-------------RLRTAYTNTQLLELE 168
           L+  +P++SD  K ++    ++ A G G  S+             R RT  T  Q    +
Sbjct: 153 LSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFK 212

Query: 169 KEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK----RQTQCKENQNSE 220
             F  +   CR  R  +AA   L+ R V+VWFQN+R K K    R  Q +E QNS+
Sbjct: 213 ASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQ 268



>gi|3914276|sp|O43316|PAX4_HUMAN   Paired box protein Pax-4
          Length = 350

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 26/65 (40%), Positives = 35/65 (53%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G   R RT ++ +Q   LEKEF   +Y     R ++A    L E  V+VWF NRR K +R
Sbjct: 168 GTGHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRR 227

Query: 210 QTQCK 214
           Q + K
Sbjct: 228 QEKLK 232



>gi|417425|sp|P32242|OTX1_HUMAN   Homeobox protein OTX1
          Length = 354

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 32/95 (33%), Positives = 48/95 (50%), Gaps = 6/95 (6%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGG------GSRRLRTAYTNTQLLELEKEFHFNKYL 177
           YL QP    +       ++++   S G        RR RT +T +QL  LE  F   +Y 
Sbjct: 4   YLKQPPYGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYP 63

Query: 178 CRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
               R E+A  ++L E +V+VWF+NRR K ++Q Q
Sbjct: 64  DIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ 98



>gi|6685480|sp|O15499|GSCL_HUMAN   Homeobox protein goosecoid-like (GSC-2)
          Length = 205

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 26/67 (38%), Positives = 37/67 (55%)

Query: 144 IADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNR 203
           +  GS   +RR RT ++  QL  LE  F  N+Y     R  +A  + L E +V+VWF+NR
Sbjct: 118 VGPGSQRRTRRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNR 177

Query: 204 RMKHKRQ 210
           R K + Q
Sbjct: 178 RAKWRHQ 184



>gi|37537960|sp|Q8NHV9|PEPP1_HUMAN   Paired-like homeobox protein PEPP-1 (Ovary-, testis- and
           epididymis-expressed gene protein)
          Length = 184

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 24/57 (42%), Positives = 35/57 (61%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R  RT +T  Q+ ELE  F   +Y   P R E+A  L +TE +V+VWF+N+R + +R
Sbjct: 104 RTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRR 160



>gi|6093787|sp|O75360|PROP1_HUMAN   Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary specific
           homeodomain factor)
          Length = 226

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 24/58 (41%), Positives = 35/58 (60%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT ++  QL +LE  F  N+Y     R  +A    L+E +++VWFQNRR K ++Q
Sbjct: 70  RRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQ 127



>gi|25009572|sp|Q9NZR4|VSX1_HUMAN   Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner
           nuclear layer homeobox protein) (Homeodomain protein
           RINX)
          Length = 365

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 25/58 (43%), Positives = 34/58 (58%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQ 210
           RR RT +T  QL ELEK F    Y     R  +A   +L E +++VWFQNRR K +++
Sbjct: 165 RRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222



>gi|20138668|sp|Q969G2|LHX4_HUMAN   LIM/homeobox protein Lhx4
          Length = 367

 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 29/74 (39%), Positives = 39/74 (52%), Gaps = 3/74 (4%)

Query: 139 KESLEIA---DGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQ 195
           KE  E A   D S  G++R RT  T  QL  L+  +  +    R  R ++++   L  R 
Sbjct: 118 KEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRV 177

Query: 196 VKVWFQNRRMKHKR 209
           V+VWFQNRR K KR
Sbjct: 178 VQVWFQNRRAKEKR 191



>gi|123402|sp|P09086|PO2F2_HUMAN   POU domain, class 2, transcription factor 2 (Octamer-binding
           transcription factor 2) (Oct-2) (OTF-2)
           (Lymphoid-restricted immunoglobulin octamer binding
           protein NF-A2)
          Length = 479

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 5/86 (5%)

Query: 128 PAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAA 187
           P+PNQ        SL   DG  G  R+ RT+        LEK F  N+       + IA 
Sbjct: 278 PSPNQLSSP----SLGF-DGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAE 332

Query: 188 LLDLTERQVKVWFQNRRMKHKRQTQC 213
            L + +  ++VWF NRR K KR   C
Sbjct: 333 QLHMEKEVIRVWFCNRRQKEKRINPC 358



>gi|18202510|sp|Q15911|ATBF1_HUMAN   Alpha-fetoprotein enhancer binding protein (AT motif-binding factor)
            (AT-binding transcription factor 1)
          Length = 3703

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 4/73 (5%)

Query: 150  GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
            G  R  RT +T+ QL  L+  F  N Y       +++ LL+L  R + VWFQN R K ++
Sbjct: 2240 GSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARK 2299

Query: 210  QTQCKENQNSEGK 222
                 ENQ  EGK
Sbjct: 2300 N---YENQ-GEGK 2308



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 10/85 (11%)

Query: 128  PAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAA 187
            P+P  S    K        G   G +R RT  TN QL  L+    FN Y   P  +E   
Sbjct: 2926 PSPGASGSAGKSGD----SGDRPGQKRFRTQMTNLQLKVLKS--CFNDYRT-PTMLECEV 2978

Query: 188  L---LDLTERQVKVWFQNRRMKHKR 209
            L   + L +R V+VWFQN R K K+
Sbjct: 2979 LGNDIGLPKRVVQVWFQNARAKEKK 3003



 Score = 35.4 bits (80), Expect = 0.033
 Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 4/67 (5%)

Query: 147  GSGGGS----RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQN 202
            G+GG      +RLRT  T  QL  L +++  +    R     IA  + L +R V+VWFQN
Sbjct: 2632 GTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQN 2691

Query: 203  RRMKHKR 209
             R + ++
Sbjct: 2692 TRARERK 2698



 Score = 31.6 bits (70), Expect = 0.48
 Identities = 17/61 (27%), Positives = 31/61 (50%)

Query: 152  SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
            ++R RT  T+ QL  L + F  N      +  E+A    L ++ +K WF+N   K +++ 
Sbjct: 2145 NKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRN 2204

Query: 212  Q 212
            +
Sbjct: 2205 K 2205



>gi|37537987|sp|Q9BQY4|PEP2_HUMAN   Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1)
          Length = 288

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 21/61 (34%), Positives = 35/61 (57%)

Query: 158 AYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQ 217
           A+T  QL ELE+ F   ++     R  +A  +++TE  V++WF+NRR K +R  +    +
Sbjct: 140 AFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMAR 199

Query: 218 N 218
           N
Sbjct: 200 N 200



>gi|18202938|sp|Q9H2C1|LHX5_HUMAN   LIM/homeobox protein Lhx5
          Length = 402

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 131 NQSDKDKKKESLEIADGSGGGSRR-LRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 189
           N +  DK+  + E  + + G  RR  RT     QL  L+  F       R  R ++A   
Sbjct: 158 NSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQET 217

Query: 190 DLTERQVKVWFQNRRMKHKRQTQ 212
            L  R ++VWFQNRR K +R  Q
Sbjct: 218 GLNMRVIQVWFQNRRSKERRMKQ 240



>gi|8247936|sp|P50458|LHX2_HUMAN   LIM/homeobox protein Lhx2 (Homeobox protein LH-2)
          Length = 406

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 7/100 (7%)

Query: 117 AAREHSLYLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKY 176
           AA   +L  N+      D+D+   S +        ++R+RT++ + QL  ++  F  N  
Sbjct: 238 AAYNAALSCNENDAEHLDRDQPYPSSQ-------KTKRMRTSFKHHQLRTMKSYFAINHN 290

Query: 177 LCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKEN 216
                  ++A    LT+R ++VWFQN R K +R    +EN
Sbjct: 291 PDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQEN 330



>gi|8134548|sp|Q9UPM6|LHX61_HUMAN   LIM/homeobox protein Lhx6.1 (Lhx6)
          Length = 363

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 12/95 (12%)

Query: 117 AAREHSLYLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKY 176
           A   + L L    P++ D   K             ++R RT++T  QL  ++ +F  +  
Sbjct: 196 AENGNGLTLEGAVPSEQDSQPKP------------AKRARTSFTAEQLQVMQAQFAQDNN 243

Query: 177 LCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
                  ++A +  L+ R ++VWFQN R +HK+ T
Sbjct: 244 PDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHT 278



>gi|12643346|sp|Q9NQ69|LHX9_HUMAN   LIM/homeobox protein Lhx9
          Length = 388

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 21/65 (32%), Positives = 36/65 (55%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           ++R+RT++ + QL  ++  F  N         ++A    LT+R ++VWFQN R K +R  
Sbjct: 258 TKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNL 317

Query: 212 QCKEN 216
             +EN
Sbjct: 318 LRQEN 322



>gi|60416412|sp|P48742|LHX1_HUMAN   LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox
           protein Lim-1)
          Length = 406

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 29/78 (37%), Positives = 37/78 (47%), Gaps = 1/78 (1%)

Query: 136 DKKKESLEIADGSGGGSRR-LRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTER 194
           DK+  S E  D + G  RR  RT     QL  L+  F       R  R ++A    L  R
Sbjct: 163 DKEAGSNENDDQNLGAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMR 222

Query: 195 QVKVWFQNRRMKHKRQTQ 212
            ++VWFQNRR K +R  Q
Sbjct: 223 VIQVWFQNRRSKERRMKQ 240



>gi|12643415|sp|Q9UBR4|LHX3_HUMAN   LIM/homeobox protein Lhx3
          Length = 397

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 22/58 (37%), Positives = 33/58 (56%)

Query: 152 SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           ++R RT  T  QL  L+  ++ +    R  R ++++   L  R V+VWFQNRR K KR
Sbjct: 157 AKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKR 214



>gi|2506535|sp|Q01851|PO4F1_HUMAN   POU domain, class 4, transcription factor 1 (Brain-specific
           homeobox/POU domain protein 3A) (Brn-3A) (Oct-T1)
           (Homeobox/POU domain protein RDC-1)
          Length = 423

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 183
           +L +    Q +K  K E       +GG  +R RT+    +   LE  F         +  
Sbjct: 336 WLEEAEGAQREKMNKPELF-----NGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIA 390

Query: 184 EIAALLDLTERQVKVWFQNRRMKHKR 209
            IA  LDL +  V+VWF N+R K KR
Sbjct: 391 AIAEKLDLKKNVVRVWFCNQRQKQKR 416



>gi|28202257|sp|P14859|PO2F1_HUMAN   POU domain, class 2, transcription factor 1 (Octamer-binding
           transcription factor 1) (Oct-1) (OTF-1) (NF-A1)
          Length = 743

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 29/88 (32%), Positives = 39/88 (44%), Gaps = 2/88 (2%)

Query: 124 YLNQPAPNQSDKDKKKESLEIADGSGGGSRRL--RTAYTNTQLLELEKEFHFNKYLCRPR 181
           +LN      SD      S   + G  G SRR   RT+      + LEK F  N+      
Sbjct: 349 WLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEE 408

Query: 182 RVEIAALLDLTERQVKVWFQNRRMKHKR 209
              IA  L++ +  ++VWF NRR K KR
Sbjct: 409 ITMIADQLNMEKEVIRVWFCNRRQKEKR 436



>gi|28201861|sp|Q9UKI9|PO2F3_HUMAN   POU domain, class 2, transcription factor 3 (Octamer-binding
           transcription factor 11) (Oct-11) (Transcription factor
           Skn-1) (PLA-1 protein)
          Length = 436

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 23/60 (38%), Positives = 28/60 (46%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G  R+ RT+      L LEK F  N          IA  L + +  V+VWF NRR K KR
Sbjct: 279 GRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338



>gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN   Zinc finger homeobox protein 2
          Length = 1427

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 22/59 (37%), Positives = 29/59 (49%)

Query: 151 GSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G R  RT +T  Q   L+  F  + Y        +A+LL L  R V VWFQN R K ++
Sbjct: 449 GRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK 507



 Score = 32.3 bits (72), Expect = 0.28
 Identities = 18/61 (29%), Positives = 30/61 (49%)

Query: 149 GGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           G G RR RT  ++ QL  ++  +   +         +   + L +R ++VWFQN R K K
Sbjct: 917 GMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEK 976

Query: 209 R 209
           +
Sbjct: 977 K 977



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 9/91 (9%)

Query: 128 PAPNQSDKDKKKESLEIADGS---GGGS------RRLRTAYTNTQLLELEKEFHFNKYLC 178
           P P    K K ++      GS   GGG       +RLRT     QL  L + +  +    
Sbjct: 679 PMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPT 738

Query: 179 RPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           R     I+  + L +R V+VWFQN R + ++
Sbjct: 739 RKMLDCISEEVGLKKRVVQVWFQNTRARERK 769



>gi|47117872|sp|P78412|IRX6_HUMAN   Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein
           6) (Homeodomain protein IRXB3)
          Length = 445

 Score = 37.0 bits (84), Expect = 0.011
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           SG G R+  T  T + L     E   N Y  +  ++ +A +  +T  QV  WF N R + 
Sbjct: 145 SGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204

Query: 208 KRQTQ 212
           K++ +
Sbjct: 205 KKENK 209



>gi|2495300|sp|Q12837|PO42_HUMAN   POU domain, class 4, transcription factor 2 (Brain-specific
           homeobox/POU domain protein 3B) (Brn-3B)
          Length = 410

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 21/62 (33%), Positives = 29/62 (46%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +G   +R RT+    +   LE  F         +   IA  LDL +  V+VWF N+R K 
Sbjct: 342 NGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQ 401

Query: 208 KR 209
           KR
Sbjct: 402 KR 403



>gi|2495302|sp|Q15319|PO43_HUMAN   POU domain, class 4, transcription factor 3 (Brain-specific
           homeobox/POU domain protein 3C) (Brn-3C)
          Length = 338

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 21/62 (33%), Positives = 29/62 (46%)

Query: 148 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +G   +R RT+    +   LE  F         +   IA  LDL +  V+VWF N+R K 
Sbjct: 270 NGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQ 329

Query: 208 KR 209
           KR
Sbjct: 330 KR 331



>gi|1345629|sp|P49335|PO3F4_HUMAN   POU domain, class 3, transcription factor 4 (Brain-specific
           homeobox/POU domain protein 4) (Brain-4) (Brn-4)
          Length = 361

 Score = 35.0 bits (79), Expect = 0.043
 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 6/55 (10%)

Query: 170 EFHFNKYLC-RPRRVEIAALLD---LTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
           E HF K  C +P   EI++L D   L +  V+VWF NRR K KR T   + Q  E
Sbjct: 294 ETHFLK--CPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDQQPHE 346



>gi|20978495|sp|Q96A47|ISL2_HUMAN   Insulin gene enhancer protein ISL-2 (Islet-2)
          Length = 359

 Score = 35.0 bits (79), Expect = 0.043
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 154 RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT-- 211
           R+RT     QL  L   +  N       + ++  +  L+ R ++VWFQN+R K K+++  
Sbjct: 193 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSIL 252

Query: 212 --QCKENQNSE 220
             Q ++ Q+S+
Sbjct: 253 MKQLQQQQHSD 263



>gi|2495306|sp|Q14863|PO6F1_HUMAN   POU domain, class 6, transcription factor 1 (mPOU homeobox protein)
           (Brain-specific homeobox/POU domain protein 5) (Brain-5)
           (Brn-5 protein)
          Length = 301

 Score = 34.7 bits (78), Expect = 0.056
 Identities = 21/79 (26%), Positives = 35/79 (44%)

Query: 134 DKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTE 193
           +++ ++  +E   G     R+ RT++T   +  L   F  N         EIA  L+   
Sbjct: 216 NQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDR 275

Query: 194 RQVKVWFQNRRMKHKRQTQ 212
             V+VWF NRR   K  ++
Sbjct: 276 EVVRVWFCNRRQTLKNTSK 294



>gi|2495290|sp|Q15475|SIX1_HUMAN   Homeobox protein SIX1 (Sine oculis homeobox homolog 1)
          Length = 284

 Score = 34.7 bits (78), Expect = 0.056
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 167 LEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
           L + +  N Y     + E+A    LT  QV  WF+NRR +  R  + KE +N+E
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR-DRAAEAKERENTE 191



>gi|12230598|sp|Q9NPC8|SIX2_HUMAN   Homeobox protein SIX2 (Sine oculis homeobox homolog 2)
          Length = 291

 Score = 34.7 bits (78), Expect = 0.056
 Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 167 LEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE 220
           L + +  N Y     + E+A    LT  QV  WF+NRR +  R  + KE +N+E
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR-DRAAEAKERENNE 191



>gi|28202258|sp|P20265|PO3F2_HUMAN   POU domain, class 3, transcription factor 2 (Nervous-system
           specific octamer-binding transcription factor N-Oct-3)
           (Brain-specific homeobox/POU domain protein 2) (Brain-2)
           (Brn-2 protein)
          Length = 443

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 6/46 (13%)

Query: 170 EFHFNKYLC-RPRRVEIAALLD---LTERQVKVWFQNRRMKHKRQT 211
           E HF K  C +P   EI +L D   L +  V+VWF NRR K KR T
Sbjct: 370 ESHFLK--CPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKRMT 413



>gi|47606423|sp|P61371|ISL1_HUMAN   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606425|sp|P61373|ISL1_MESAU   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606424|sp|P61372|ISL1_MOUSE   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606422|sp|P61374|ISL1_RAT   Insulin gene enhancer protein ISL-1 (Islet-1)
          Length = 349

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 17/58 (29%), Positives = 30/58 (51%)

Query: 154 RLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT 211
           R+RT     QL  L   +  N       + ++  +  L+ R ++VWFQN+R K K+++
Sbjct: 183 RVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRS 240



>gi|12644347|sp|P78413|IRX4_HUMAN   Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein
           4) (Homeodomain protein IRXA3)
          Length = 519

 Score = 32.7 bits (73), Expect = 0.21
 Identities = 17/63 (26%), Positives = 30/63 (47%)

Query: 150 GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 209
           G  R+  T  T + L    +E   N Y  +  ++ +A +  +T  QV  WF N R + K+
Sbjct: 143 GTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKK 202

Query: 210 QTQ 212
           + +
Sbjct: 203 ENK 205



>gi|1709437|sp|Q03052|PO3F1_HUMAN   POU domain, class 3, transcription factor 1 (Octamer-binding
           transcription factor 6) (Oct-6) (POU-domain
           transcription factor SCIP)
          Length = 448

 Score = 32.7 bits (73), Expect = 0.21
 Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 6/46 (13%)

Query: 170 EFHFNKYLC-RPRRVEIAALLD---LTERQVKVWFQNRRMKHKRQT 211
           E HF K  C +P   EI  L D   L +  V+VWF NRR K KR T
Sbjct: 352 ESHFLK--CPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMT 395



>gi|2506534|sp|P20264|PO33_HUMAN   POU domain, class 3, transcription factor 3 (Brain-specific
           homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein)
          Length = 500

 Score = 32.3 bits (72), Expect = 0.28
 Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 6/46 (13%)

Query: 170 EFHFNKYLC-RPRRVEIAALLD---LTERQVKVWFQNRRMKHKRQT 211
           E HF K  C +P   EI  L D   L +  V+VWF NRR K KR T
Sbjct: 422 ESHFLK--CPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKRMT 465



>gi|12230612|sp|Q9UIU6|SIX4_HUMAN   Homeobox protein SIX4 (Sine oculis homeobox homolog 4)
          Length = 760

 Score = 32.3 bits (72), Expect = 0.28
 Identities = 14/55 (25%), Positives = 29/55 (52%)

Query: 167 LEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG 221
           L++ +  N+Y     +  +A +  L+  QV  WF+NRR + +  ++ +    S+G
Sbjct: 217 LKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDG 271



>gi|28201884|sp|P78424|PO6F2_HUMAN   POU domain, class 6, transcription factor 2 (Retina-derived
           POU-domain factor-1) (RPF-1)
          Length = 684

 Score = 32.3 bits (72), Expect = 0.28
 Identities = 19/56 (33%), Positives = 26/56 (46%)

Query: 153 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           R+ RT++T   L  L   F  N +       EIA  L+     V+VWF N+R   K
Sbjct: 601 RKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALK 656



>gi|20141754|sp|P41778|PBX1_MOUSE   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
 gi|730279|sp|P40424|PBX1_HUMAN   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
           (Homeobox protein PRL)
          Length = 430

 Score = 32.0 bits (71), Expect = 0.36
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 5/62 (8%)

Query: 152 SRRLRTAYTNTQLLELEKEFHF----NKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +RR R  + N Q  E+  E+ +    N Y     + E+A    +T  QV  WF N+R+++
Sbjct: 233 ARRKRRNF-NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY 291

Query: 208 KR 209
           K+
Sbjct: 292 KK 293



>gi|28201859|sp|Q9BZV7|PO5M_HUMAN   POU domain, class 5, transcription factor 1-like protein 2
          Length = 359

 Score = 31.6 bits (70), Expect = 0.48
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 132 QSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV----EIAA 187
           ++D D+  + +  A+      +R RT+  N     LE     N +L  P+       IA 
Sbjct: 210 EADNDENLQEICKAETLMQARKRKRTSIENRVRGNLE-----NLFLQCPKPTLQISHIAQ 264

Query: 188 LLDLTERQVKVWFQNRRMKHKRQT 211
            L L +  V+VWF NRR K KR +
Sbjct: 265 QLGLEKDVVRVWFCNRRQKGKRSS 288



>gi|123408|sp|P28069|PIT1_HUMAN   Pituitary-specific positive transcription factor 1 (Pit-1) (Growth
           hormone factor 1) (GHF-1)
          Length = 291

 Score = 31.2 bits (69), Expect = 0.62
 Identities = 19/63 (30%), Positives = 29/63 (46%)

Query: 147 GSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 206
           G+    R+ RT  +      LE+ F           + +A  L+L +  V+VWF NRR +
Sbjct: 209 GANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQR 268

Query: 207 HKR 209
            KR
Sbjct: 269 EKR 271



>gi|730281|sp|P40426|PBX3_HUMAN   Pre-B-cell leukemia transcription factor-3 (Homeobox protein PBX3)
          Length = 434

 Score = 30.8 bits (68), Expect = 0.81
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 5/62 (8%)

Query: 152 SRRLRTAYTNTQLLELEKEFHF----NKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +RR R  ++  Q  E+  E+ +    N Y     + E+A    +T  QV  WF N+R+++
Sbjct: 235 ARRKRRNFSK-QATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRY 293

Query: 208 KR 209
           K+
Sbjct: 294 KK 295



>gi|1350590|sp|P47736|RGP2_HUMAN   Rap1 GTPase-activating protein 1 (Rap1GAP)
          Length = 663

 Score = 30.4 bits (67), Expect = 1.1
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 15/103 (14%)

Query: 269 QAPNGHNGDSQSFPVSPLTSNE--------KNLKHFQHQSPTVPNCLSTMGQNCGAGLNN 320
           Q P   N  +QS P  P T N         + LK F   S +  +  S + +  G    +
Sbjct: 530 QEPKSENSSTQSSPEMPTTKNRAETAAQRAEALKDFSRSSSSASSFASVVEETEGVDGED 589

Query: 321 DSPEALE---VPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSP 360
              E++     P  +D  ++ST     L D+VS +  GS   P
Sbjct: 590 TGLESVSSSGTPHKRDSFIYST----WLEDSVSTTSGGSSPGP 628



>gi|1352729|sp|P40425|PBX2_HUMAN   Pre-B-cell leukemia transcription factor-2 (Homeobox protein PBX2)
           (G17 protein)
          Length = 430

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 5/62 (8%)

Query: 152 SRRLRTAYTNTQLLELEKEFHF----NKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +RR R  ++  Q  E+  E+ +    N Y     + E+A    +T  QV  WF N+R+++
Sbjct: 244 ARRKRRNFSK-QATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY 302

Query: 208 KR 209
           K+
Sbjct: 303 KK 304



>gi|6919875|sp|Q92997|DVL3_HUMAN   Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3)
           (DSH homolog 3)
          Length = 716

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 1/60 (1%)

Query: 94  PTTEPGSKHPRCPRIRKVWEAVQAAREHSLYLNQPAPNQSDKDKKKE-SLEIADGSGGGS 152
           P   P + HP  P +   +    A+ +HS        N+S  D++KE   +  D   GGS
Sbjct: 542 PPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGGS 601



>gi|28201858|sp|Q06416|PO5L_HUMAN   POU domain, class 5, transcription factor 1-like protein 1 (Octamer
           binding protein 3-like)
          Length = 359

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 9/84 (10%)

Query: 132 QSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV----EIAA 187
           ++D ++  + +  A+      +R RT+  N     LE     N +L  P+       IA 
Sbjct: 210 EADNNENLQEICKAETLMQARKRKRTSIENRVRGNLE-----NLFLQCPKPTLQISHIAQ 264

Query: 188 LLDLTERQVKVWFQNRRMKHKRQT 211
            L L +  V+VWF NRR K KR +
Sbjct: 265 QLGLEKDVVRVWFCNRRQKGKRSS 288



>gi|38258267|sp|Q9UK17|KCD3_HUMAN   Potassium voltage-gated channel subfamily D member 3 (Voltage-gated
           potassium channel subunit Kv4.3)
          Length = 655

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 4/54 (7%)

Query: 126 NQPAP-NQSDKDKKKESLEIADGSGGGSRRLRTA---YTNTQLLELEKEFHFNK 175
           N P P   +DK+K+++ L + + SG   +  RT    Y +T L   EKEF FN+
Sbjct: 24  NCPMPLAPADKNKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNE 77



>gi|44888551|sp|Q9UKY1|ZHX1_HUMAN   Zinc fingers and homeoboxes protein 1
          Length = 873

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 10/23 (43%), Positives = 16/23 (69%)

Query: 185 IAALLDLTERQVKVWFQNRRMKH 207
           ++A    TE Q+K+WF  +R+KH
Sbjct: 317 LSAQAKYTEEQIKIWFSAQRLKH 339



>gi|400659|sp|Q01860|PO5F1_HUMAN   POU domain, class 5, transcription factor 1 (Octamer-binding
           transcription factor 3) (Oct-3) (Oct-4)
          Length = 360

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 132 QSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDL 191
           ++D ++  + +  A+      +R RT+  N     LE  F         +   IA  L L
Sbjct: 210 EADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGL 269

Query: 192 TERQVKVWFQNRRMKHKRQT 211
            +  V+VWF NRR K KR +
Sbjct: 270 EKDVVRVWFCNRRQKGKRSS 289



>gi|37999770|sp|Q9BYU1|PBX4_HUMAN   Pre-B-cell leukemia transcription factor-4 (Homeobox protein PBX4)
          Length = 330

 Score = 29.3 bits (64), Expect = 2.4
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 5/62 (8%)

Query: 152 SRRLRTAYTNTQLLELEKEFHF----NKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 207
           +RR R  ++  Q  E+  E+ +    N Y     + E+A    LT  QV  WF N+R+++
Sbjct: 166 ARRKRRNFSK-QATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRY 224

Query: 208 KR 209
           K+
Sbjct: 225 KK 226



>gi|22096235|sp|Q9UBB9|TP11_HUMAN   Tuftelin-interacting protein 11 (HSPC006)
          Length = 837

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 16/78 (20%), Positives = 42/78 (53%), Gaps = 3/78 (3%)

Query: 132 QSDKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRR-VEIAALLD 190
           +++++ +KE  +      G  ++ + +Y   +  EL+ +   +K L  P++ +    ++D
Sbjct: 213 EAEEEFQKELSQWRKDPSGSKKKPKYSYKTVE--ELKAKGRISKKLTAPQKELSQVKVID 270

Query: 191 LTERQVKVWFQNRRMKHK 208
           +T R+ KV++   ++ HK
Sbjct: 271 MTGREQKVYYSYSQISHK 288



>gi|47117873|sp|P78414|IRX1_HUMAN   Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein
           1) (Homeodomain protein IRXA1)
          Length = 480

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 170 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           E   N Y  +  ++ +A +  +T  QV  WF N R + K++ +
Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 190



>gi|47117871|sp|P78411|IRX5_HUMAN   Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein
           5) (Homeodomain protein IRXB2) (IRX-2A)
          Length = 482

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 170 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           E   N Y  +  ++ +A +  +T  QV  WF N R + K++ +
Sbjct: 134 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 176



>gi|47117874|sp|P78415|IRX3_HUMAN   Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein
           3) (Homeodomain protein IRXB1)
          Length = 501

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 170 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           E   N Y  +  ++ +A +  +T  QV  WF N R + K++ +
Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 190



>gi|47117908|sp|Q9BZI1|IRX2_HUMAN   Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein
           2) (Homeodomain protein IRXA2)
          Length = 471

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 12/43 (27%), Positives = 22/43 (51%)

Query: 170 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 212
           E   N Y  +  ++ +A +  +T  QV  WF N R + K++ +
Sbjct: 135 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 177



>gi|28380041|sp|Q9BYJ9|YTH1_HUMAN   YTH domain protein 1 (Dermatomyositis associated with cancer
           putative autoantigen-1) (DACA-1)
          Length = 559

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 12/81 (14%)

Query: 268 QQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVP---------NCLSTMGQNCGAGL 318
           QQAP+            PL +    L   Q+QSP  P         N  +  GQ+ GAG 
Sbjct: 287 QQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGS 346

Query: 319 NNDSPEALE---VPSLQDFSV 336
           +++SP  ++    PS++   V
Sbjct: 347 DSNSPGNVQPNSAPSVESHPV 367



>gi|2495295|sp|Q15583|TGIF_HUMAN   5'-TG-3' interacting factor (Homeobox protein TGIF)
          Length = 272

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 3/76 (3%)

Query: 134 DKDKKKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAAL---LD 190
           D+D     L+++  +G G RR R       +  L    + ++Y   P   E A L     
Sbjct: 17  DEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTH 76

Query: 191 LTERQVKVWFQNRRMK 206
           L+  QV  WF N R +
Sbjct: 77  LSTLQVCNWFINARRR 92



>gi|51316484|sp|Q8N5B7|LSS5_HUMAN   LAG1 longevity assurance homolog 5
          Length = 392

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 1/49 (2%)

Query: 167 LEKEF-HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 214
           LEK F    KY  + R   ++  LD   R+++ WF++RR + K  T  K
Sbjct: 92  LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTK 140



>gi|12643733|sp|Q16799|RTN1_HUMAN   Reticulon 1 (Neuroendocrine-specific protein)
          Length = 776

 Score = 28.1 bits (61), Expect = 5.3
 Identities = 13/45 (28%), Positives = 24/45 (53%)

Query: 318 LNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVD 362
           L    P   +VP ++   +FS+DS ++++ A S  +   L  P+D
Sbjct: 143 LGTPGPSLPDVPGIESRGLFSSDSGIEMTPAESTEVNKILADPLD 187



>gi|50401058|sp|Q8IU89|LSS3_HUMAN   LAG1 longevity assurance homolog 3
          Length = 383

 Score = 28.1 bits (61), Expect = 5.3
 Identities = 14/35 (40%), Positives = 24/35 (68%), Gaps = 1/35 (2%)

Query: 185 IAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNS 219
           +A   +LTERQV+ WF++RR   +R ++ K+ Q +
Sbjct: 102 LAKKCNLTERQVERWFRSRR-NQERPSRLKKFQEA 135



>gi|3913115|sp|Q92858|ATOH1_HUMAN   Atonal protein homolog 1 (Helix-loop-helix protein hATH-1)
          Length = 354

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 5/64 (7%)

Query: 299 QSPTVP-NCLSTMGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSL 357
           Q PT P +C +       AG  +   +AL   + +D ++    + +     +SPSLPGS+
Sbjct: 264 QRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDSAL----TAMMAQKNLSPSLPGSI 319

Query: 358 DSPV 361
             PV
Sbjct: 320 LQPV 323



>gi|13124379|sp|O95897|NOE2_HUMAN   Noelin 2 precursor (Olfactomedin 2)
          Length = 454

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 6/81 (7%)

Query: 256 EGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCG 315
           +G  F Q+ L Q  A  GH   + S   +   SN     HF+ +S  V   L       G
Sbjct: 253 KGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLP------G 306

Query: 316 AGLNNDSPEALEVPSLQDFSV 336
           AG NN  P +    S  DF V
Sbjct: 307 AGYNNTFPYSWGGFSDMDFMV 327



>gi|46396941|sp|Q8N196|SIX5_HUMAN   Homeobox protein SIX5 (DM locus-associated homeodomain protein)
          Length = 739

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 12/35 (34%), Positives = 19/35 (54%)

Query: 174 NKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHK 208
           N+Y     +  +A L  L+  QV  WF+NRR + +
Sbjct: 223 NRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDR 257






  Database: Non-redundant SwissProt sequences
    Posted date:  Mar 15, 2005 10:11 AM
  Number of letters in database: 60,490,055
  Number of sequences in database:  164,271
  
Lambda     K      H
   0.314    0.130    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 834,173
Number of Sequences: 164271
Number of extensions: 36556
Number of successful extensions: 110
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 80
Number of HSP's gapped (non-prelim): 32
length of query: 385
length of database: 6,424,444
effective HSP length: 97
effective length of query: 288
effective length of database: 5,269,659
effective search space: 1517661792
effective search space used: 1517661792
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 59 (27.3 bits)