BLASTP 2.2.10 [Oct-19-2004]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1111164463-25694-161931642577.BLASTQ4

Query= FGENESH:   4   3 exon (s) 176539  - 177996   282 aa,
chain -
         (282 letters)


Database: Non-redundant SwissProt sequences 
           164,271 sequences; 60,490,055 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs

Taxonomy reports

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6166216|sp|P49639|HXA1_HUMAN  Homeobox protein Hox-A1 (Ho...   494   e-140 
gi|123271|sp|P14653|HXB1_HUMAN  Homeobox protein Hox-B1 (Hox...   181   3e-46 
gi|17378648|sp|Q9GZZ0|HXD1_HUMAN  Homeobox protein Hox-D1         156   6e-39 
gi|20141491|sp|P09016|HXD4_HUMAN  Homeobox protein Hox-D4 (H...    95   3e-20 
gi|123279|sp|P09017|HXC4_HUMAN  Homeobox protein Hox-C4 (Hox...    95   3e-20 
gi|123270|sp|P14652|HXB2_HUMAN  Homeobox protein Hox-B2 (Hox...    92   1e-19 
gi|6016293|sp|O43365|HXA3_HUMAN  Homeobox protein Hox-A3 (Ho...    91   3e-19 
gi|547692|sp|P17483|HXB4_HUMAN  Homeobox protein Hox-B4 (Hox...    91   4e-19 
gi|6166217|sp|Q00056|HXA4_HUMAN  Homeobox protein Hox-A4 (Ho...    90   7e-19 
gi|6166222|sp|P31249|HXD3_HUMAN  Homeobox protein Hox-D3 (Ho...    89   2e-18 
gi|17378385|sp|P31267|HXA6_HUMAN  Homeobox protein Hox-A6 (H...    87   5e-18 
gi|6016292|sp|O43364|HXA2_HUMAN  Homeobox protein Hox-A2           87   5e-18 
gi|232262|sp|Q00444|HXC5_HUMAN  Homeobox protein Hox-C5 (Hox...    87   6e-18 
gi|400000|sp|P09067|HXB5_HUMAN  Homeobox protein Hox-B5 (Hox...    87   8e-18 
gi|13124738|sp|P17509|HXB6_HUMAN  Homeobox protein Hox-B6 (H...    86   1e-17 
gi|3915721|sp|P31268|HXA7_HUMAN  Homeobox protein Hox-A7 (Ho...    85   3e-17 
gi|45644931|sp|P50219|HLXB9_HUMAN  Homeobox protein HB9            84   4e-17 
gi|13124737|sp|P13378|HXD8_HUMAN  Homeobox protein Hox-D8 (H...    84   7e-17 
gi|123268|sp|P14651|HXB3_HUMAN  Homeobox protein Hox-B3 (Hox...    84   7e-17 
gi|52788238|sp|P20719|HXA5_HUMAN  Homeobox protein Hox-A5 (H...    84   7e-17 
gi|1708540|sp|P52945|IPF1_HUMAN  Insulin promoter factor-1 (...    83   9e-17 
gi|20141282|sp|Q99626|CDX2_HUMAN  Homeobox protein CDX-2 (Ca...    82   3e-16 
gi|123255|sp|P09629|HXB7_HUMAN  Homeobox protein Hox-B7 (Hox...    81   3e-16 
gi|13124745|sp|P31273|HXC8_HUMAN  Homeobox protein Hox-C8 (H...    80   6e-16 
gi|20141493|sp|P09630|HXC6_HUMAN  Homeobox protein Hox-C6 (H...    80   6e-16 
gi|12644308|sp|P52951|GBX2_HUMAN  Homeobox protein GBX-2 (Ga...    79   1e-15 
gi|1345720|sp|P47902|CDX1_HUMAN  Homeobox protein CDX-1 (Cau...    78   3e-15 
gi|20141506|sp|P17481|HXB8_HUMAN  Homeobox protein Hox-B8 (H...    78   4e-15 
gi|20141507|sp|P17482|HXB9_HUMAN  Homeobox protein Hox-B9 (H...    77   6e-15 
gi|27923786|sp|Q9H4S2|GSHI_HUMAN  Homeobox protein GSH-1           77   8e-15 
gi|20138327|sp|Q9BZM3|GSH2_HUMAN  Homeobox protein GSH-2           76   1e-14 
gi|1709078|sp|P50221|MEOX1_HUMAN  Homeobox protein MOX-1 (Me...    75   2e-14 
gi|20141537|sp|P31274|HXC9_HUMAN  Homeobox protein Hox-C9 (H...    75   3e-14 
gi|123286|sp|P28356|HXD9_HUMAN  Homeobox protein Hox-D9 (Hox...    75   3e-14 
gi|123289|sp|P28358|HXD10_HUMAN  Homeobox protein Hox-D10 (H...    74   5e-14 
gi|13124743|sp|P31260|HXA10_HUMAN  Homeobox protein Hox-A10 ...    74   7e-14 
gi|20141612|sp|Q9NYD6|HXC10_HUMAN  Homeobox protein Hox-C10        73   9e-14 
gi|6166219|sp|P31269|HXA9_HUMAN  Homeobox protein Hox-A9 (Ho...    73   9e-14 
gi|1709079|sp|P50222|MEOX2_HUMAN  Homeobox protein MOX-2 (Me...    73   1e-13 
gi|57015304|sp|Q04741|EMX1_HUMAN  Homeobox protein EMX1 (Emp...    73   1e-13 
gi|12230077|sp|Q14549|GBX1_HUMAN  Homeobox protein GBX-1 (Ga...    72   3e-13 
gi|23503066|sp|P28360|MSX1_HUMAN  Homeobox protein MSX-1 (Ho...    71   4e-13 
gi|1352398|sp|P49640|EVX1_HUMAN  Homeobox even-skipped homol...    71   4e-13 
gi|12231013|sp|Q03828|EVX2_HUMAN  Homeobox even-skipped homo...    71   5e-13 
gi|20532295|sp|Q9UIW0|VAX2_HUMAN  Ventral anterior homeobox 2      70   8e-13 
gi|3023467|sp|O14627|CDX4_HUMAN  Homeobox protein CDX-4 (Cau...    70   1e-12 
gi|29336920|sp|Q9BZE3|BARH1_HUMAN  BarH-like 1 homeobox prot...    69   1e-12 
gi|13959687|sp|P35548|MSX2_HUMAN  Homeobox protein MSX-2 (Ho...    69   1e-12 
gi|2506529|sp|Q07687|DLX2_HUMAN  Homeobox protein DLX-2            69   2e-12 
gi|14917010|sp|Q05925|HME1_HUMAN  Homeobox protein engrailed...    69   2e-12 
gi|3287858|sp|O43248|HXC11_HUMAN  Homeobox protein Hox-C11         68   4e-12 
gi|399982|sp|P31314|TLX1_HUMAN  T-cell leukemia homeobox pro...    68   4e-12 
gi|12644227|sp|P35452|HXD12_HUMAN  Homeobox protein Hox-D12 ...    67   5e-12 
gi|3913487|sp|O60479|DLX3_HUMAN  Homeobox protein DLX-3            67   9e-12 
gi|21903415|sp|P19622|HME2_HUMAN  Homeobox protein engrailed...    67   9e-12 
gi|12644203|sp|P31277|HXD11_HUMAN  Homeobox protein Hox-D11 ...    67   9e-12 
gi|6016210|sp|P78367|NK32_HUMAN  Homeobox protein Nkx-3.2 (B...    66   1e-11 
gi|14194481|sp|Q9HBU1|BARX1_HUMAN  Homeobox protein BarH-like 1    65   2e-11 
gi|19862512|sp|Q04743|EMX2_HUMAN  Homeobox protein EMX2 (Emp...    65   3e-11 
gi|12644329|sp|P56178|DLX5_HUMAN  Homeobox protein DLX-5           65   3e-11 
gi|13124744|sp|P31270|HXA11_HUMAN  Homeobox protein Hox-A11 ...    64   4e-11 
gi|13431329|sp|Q9UMQ3|BARX2_HUMAN  Homeobox protein BarH-like 2    64   6e-11 
gi|47117915|sp|Q9NY43|BARH2_HUMAN  BarH-like 2 homeobox protein    64   6e-11 
gi|23831508|sp|O43711|TLX3_HUMAN  T-cell leukemia homeobox p...    64   6e-11 
gi|12644330|sp|P56179|DLX6_HUMAN  Homeobox protein DLX-6           64   7e-11 
gi|27923815|sp|Q8TAU0|NKX23_HUMAN  Homeobox protein Nkx-2.3 ...    63   1e-10 
gi|27923733|sp|Q96QS3|ARX_HUMAN  Homeobox protein ARX (Arist...    62   2e-10 
gi|17377578|sp|Q99801|NKX31_HUMAN  Homeobox protein Nkx-3.1        62   3e-10 
gi|20141538|sp|P31275|HXC12_HUMAN  Homeobox protein Hox-C12 ...    62   3e-10 
gi|2828197|sp|P31271|HXA13_HUMAN  Homeobox protein Hox-A13 (...    61   4e-10 
gi|20141539|sp|P31276|HXC13_HUMAN  Homeobox protein Hox-C13 ...    61   5e-10 
gi|38605720|sp|P56177|DLX1_HUMAN  Homeobox protein DLX-1           61   5e-10 
gi|6174907|sp|Q99697|PITX2_HUMAN  Pituitary homeobox 2 (RIEG...    60   1e-09 
gi|6093723|sp|O75364|PITX3_HUMAN  Pituitary homeobox 3 (Home...    60   1e-09 
gi|3024482|sp|P78337|PITX1_HUMAN  Pituitary homeobox 1 (Hind...    60   1e-09 
gi|3915680|sp|Q92988|DLX4_HUMAN  Homeobox protein DLX-4 (DLX...    60   1e-09 
gi|6016205|sp|O95096|NKX22_HUMAN  Homeobox protein Nkx-2.2 (...    59   1e-09 
gi|50403792|sp|Q92826|HXB13_HUMAN  Homeobox protein Hox-B13        59   1e-09 
gi|1708211|sp|P52952|NK25_HUMAN  Homeobox protein Nkx-2.5 (H...    59   1e-09 
gi|2851475|sp|P35453|HXD13_HUMAN  Homeobox protein Hox-D13 (...    59   2e-09 
gi|20532396|sp|O43763|TLX2_HUMAN  T-cell leukemia homeobox p...    58   4e-09 
gi|6093787|sp|O75360|PROP1_HUMAN  Homeobox protein prophet o...    57   5e-09 
gi|2833256|sp|Q14774|HLX1_HUMAN  Homeobox protein HLX1 (Home...    57   5e-09 
gi|1730095|sp|P52954|LBX1_HUMAN  Transcription factor LBX1         57   5e-09 
gi|6016211|sp|P78426|NK61_HUMAN  Homeobox protein Nkx-6.1          57   7e-09 
gi|547658|sp|Q03014|HHEX_HUMAN  Homeobox protein PRH (Hemato...    57   9e-09 
gi|27923817|sp|Q9H2Z4|NK24_HUMAN  Homeobox protein Nkx-2.4 (...    56   1e-08 
gi|13626112|sp|Q9H161|ALX4_HUMAN  Homeobox protein aristales...    56   1e-08 
gi|6831676|sp|O15266|SHOX_HUMAN  Short stature homeobox prot...    56   2e-08 
gi|1174819|sp|P43699|TITF1_HUMAN  Thyroid transcription fact...    56   2e-08 
gi|3023579|sp|Q15699|CRT1_HUMAN  Cartilage homeoprotein 1 (C...    56   2e-08 
gi|18202099|sp|O60902|SHOX2_HUMAN  Short stature homeobox pr...    56   2e-08 
gi|13626107|sp|O95076|ALX3_HUMAN  Homeobox protein aristales...    55   2e-08 
gi|17380297|sp|Q9Y2V3|RX_HUMAN  Retinal homeobox protein Rx ...    55   2e-08 
gi|8134644|sp|Q99453|PHX2B_HUMAN  Paired mesoderm homeobox p...    55   3e-08 
gi|8134640|sp|O14813|PHX2A_HUMAN  Paired mesoderm homeobox p...    55   3e-08 
gi|6016208|sp|O15522|NK28_HUMAN  Homeobox protein Nkx-2.8 (H...    54   8e-08 
gi|51702790|sp|P63015|PAX6_MOUSE  Paired box protein Pax-6 (...    52   2e-07 
gi|17374365|sp|P58304|CHX10_HUMAN  Homeobox protein CHX10 (C...    52   2e-07 
gi|25009572|sp|Q9NZR4|VSX1_HUMAN  Visual system homeobox 1 (...    52   2e-07 
gi|37537960|sp|Q8NHV9|PEPP1_HUMAN  Paired-like homeobox prot...    52   2e-07 
gi|48428084|sp|Q8N693|ESX1L_HUMAN  Extraembryonic, spermatog...    51   4e-07 
gi|3287764|sp|O43186|CRX_HUMAN  Cone-rod homeobox protein          51   5e-07 
gi|8247951|sp|P23759|PAX7_HUMAN  Paired box protein Pax-7 (H...    50   1e-06 
gi|12230168|sp|Q9UBX0|HESX1_HUMAN  Homeobox expressed in ES ...    49   2e-06 
gi|1172022|sp|P23760|PAX3_HUMAN  Paired box protein Pax-3 (H...    49   2e-06 
gi|12644475|sp|Q99811|PRRX2_HUMAN  Paired mesoderm homeobox ...    49   2e-06 
gi|3914276|sp|O43316|PAX4_HUMAN  Paired box protein Pax-4          49   2e-06 
gi|417425|sp|P32242|OTX1_HUMAN  Homeobox protein OTX1              48   4e-06 
gi|6174916|sp|P54821|PRRX1_HUMAN  Paired mesoderm homeobox p...    47   7e-06 
gi|7531125|sp|P56915|GSC_HUMAN  Homeobox protein goosecoid         47   7e-06 
gi|37537987|sp|Q9BQY4|PEP2_HUMAN  Paired-like homeobox prote...    46   2e-05 
gi|6685480|sp|O15499|GSCL_HUMAN  Homeobox protein goosecoid-...    46   2e-05 
gi|417427|sp|P32243|OTX2_HUMAN  Homeobox protein OTX2              46   2e-05 
gi|18202510|sp|Q15911|ATBF1_HUMAN  Alpha-fetoprotein enhance...    45   3e-05 
gi|47117871|sp|P78411|IRX5_HUMAN  Iroquois-class homeodomain...    44   8e-05 
gi|12643415|sp|Q9UBR4|LHX3_HUMAN  LIM/homeobox protein Lhx3        43   1e-04 
gi|123402|sp|P09086|PO2F2_HUMAN  POU domain, class 2, transc...    42   3e-04 
gi|20138668|sp|Q969G2|LHX4_HUMAN  LIM/homeobox protein Lhx4        42   3e-04 
gi|47117872|sp|P78412|IRX6_HUMAN  Iroquois-class homeodomain...    41   4e-04 
gi|47117873|sp|P78414|IRX1_HUMAN  Iroquois-class homeodomain...    41   5e-04 
gi|60416412|sp|P48742|LHX1_HUMAN  LIM/homeobox protein Lhx1 ...    40   7e-04 
gi|18202938|sp|Q9H2C1|LHX5_HUMAN  LIM/homeobox protein Lhx5        40   7e-04 
gi|47117874|sp|P78415|IRX3_HUMAN  Iroquois-class homeodomain...    40   0.001 
gi|27923801|sp|Q8TE12|LMX1A_HUMAN  LIM homeobox transcriptio...    39   0.001 
gi|8247930|sp|O60663|LMX1B_HUMAN  LIM homeobox transcription...    39   0.001 
gi|28201861|sp|Q9UKI9|PO2F3_HUMAN  POU domain, class 2, tran...    39   0.001 
gi|28201884|sp|P78424|PO6F2_HUMAN  POU domain, class 6, tran...    38   0.004 
gi|8134548|sp|Q9UPM6|LHX61_HUMAN  LIM/homeobox protein Lhx6....    38   0.004 
gi|28202257|sp|P14859|PO2F1_HUMAN  POU domain, class 2, tran...    37   0.006 
gi|47117908|sp|Q9BZI1|IRX2_HUMAN  Iroquois-class homeodomain...    37   0.006 
gi|12644347|sp|P78413|IRX4_HUMAN  Iroquois-class homeodomain...    37   0.007 
gi|2495306|sp|Q14863|PO6F1_HUMAN  POU domain, class 6, trans...    37   0.007 
gi|47606423|sp|P61371|ISL1_HUMAN  Insulin gene enhancer prot...    37   0.007 
gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN  Zinc finger homeobox prot...    37   0.010 
gi|730281|sp|P40426|PBX3_HUMAN  Pre-B-cell leukemia transcri...    36   0.013 
gi|2506534|sp|P20264|PO33_HUMAN  POU domain, class 3, transc...    35   0.022 
gi|12230612|sp|Q9UIU6|SIX4_HUMAN  Homeobox protein SIX4 (Sin...    35   0.022 
gi|20141754|sp|P41778|PBX1_MOUSE  Pre-B-cell leukemia transc...    35   0.028 
gi|1352729|sp|P40425|PBX2_HUMAN  Pre-B-cell leukemia transcr...    35   0.028 
gi|2506535|sp|Q01851|PO4F1_HUMAN  POU domain, class 4, trans...    35   0.028 
gi|1345629|sp|P49335|PO3F4_HUMAN  POU domain, class 3, trans...    34   0.048 
gi|2495302|sp|Q15319|PO43_HUMAN  POU domain, class 4, transc...    34   0.048 
gi|12230598|sp|Q9NPC8|SIX2_HUMAN  Homeobox protein SIX2 (Sin...    34   0.048 
gi|37999770|sp|Q9BYU1|PBX4_HUMAN  Pre-B-cell leukemia transc...    34   0.048 
gi|28202258|sp|P20265|PO3F2_HUMAN  POU domain, class 3, tran...    34   0.063 
gi|2495300|sp|Q12837|PO42_HUMAN  POU domain, class 4, transc...    34   0.063 
gi|2495290|sp|Q15475|SIX1_HUMAN  Homeobox protein SIX1 (Sine...    33   0.11  
gi|20978495|sp|Q96A47|ISL2_HUMAN  Insulin gene enhancer prot...    33   0.11  
gi|1709437|sp|Q03052|PO3F1_HUMAN  POU domain, class 3, trans...    33   0.14  
gi|44889075|sp|Q9H4I2|ZHX3_HUMAN  Zinc fingers and homeoboxe...    32   0.31  
gi|12643346|sp|Q9NQ69|LHX9_HUMAN  LIM/homeobox protein Lhx9        31   0.41  
gi|123408|sp|P28069|PIT1_HUMAN  Pituitary-specific positive ...    31   0.53  
gi|12643330|sp|Q9Y5K3|CTPU_HUMAN  Choline-phosphate cytidyly...    31   0.53  
gi|6094293|sp|O95343|SIX3_HUMAN  Homeobox protein SIX3 (Sine...    30   0.70  
gi|46396941|sp|Q8N196|SIX5_HUMAN  Homeobox protein SIX5 (DM ...    30   0.70  
gi|8247936|sp|P50458|LHX2_HUMAN  LIM/homeobox protein Lhx2 (...    30   1.2   
gi|5921744|sp|Q14839|CHD4_HUMAN  Chromodomain helicase-DNA-b...    30   1.2   
gi|23503097|sp|P57071|PRD15_HUMAN  PR-domain zinc finger pro...    30   1.2   
gi|51316484|sp|Q8N5B7|LSS5_HUMAN  LAG1 longevity assurance h...    30   1.2   
gi|20141973|sp|Q9UHP3|UBP25_HUMAN  Ubiquitin carboxyl-termin...    29   1.6   
gi|12230578|sp|O95475|SIX6_HUMAN  Homeobox protein SIX6 (Sin...    29   1.6   
gi|14285403|sp|Q9NR82|CIQ5_HUMAN  Potassium voltage-gated ch...    29   2.0   
gi|44888551|sp|Q9UKY1|ZHX1_HUMAN  Zinc fingers and homeoboxe...    28   2.6   
gi|400659|sp|Q01860|PO5F1_HUMAN  POU domain, class 5, transc...    28   2.6   
gi|52000732|sp|Q99700|ATX2_HUMAN  Ataxin-2 (Spinocerebellar ...    28   2.6   
gi|28201897|sp|Q8N7G0|SPRM1_HUMAN  Sperm 1 POU-domain transc...    28   2.6   
gi|34098663|sp|Q92613|PHFG_HUMAN  PHD finger protein 16            28   3.5   
gi|28201858|sp|Q06416|PO5L_HUMAN  POU domain, class 5, trans...    28   3.5   
gi|28201859|sp|Q9BZV7|PO5M_HUMAN  POU domain, class 5, trans...    28   3.5   
gi|1350911|sp|P28702|RXRB_HUMAN  Retinoic acid receptor RXR-...    27   5.9   
gi|17380567|sp|Q12816|TROP_HUMAN  Trophinin (MAGE-D3 antigen)      27   7.7   
gi|37999907|sp|Q9P275|UBP36_HUMAN  Ubiquitin carboxyl-termin...    27   7.7   
gi|30173334|sp|Q8TCX5|RHN1_HUMAN  Rhophilin 1                      27   7.7   
gi|17366458|sp|Q14573|ITPR3_HUMAN  Inositol 1,4,5-trisphosph...    27   7.7   


Alignments

>gi|6166216|sp|P49639|HXA1_HUMAN   Homeobox protein Hox-A1 (Hox-1F)
          Length = 335

 Score =  494 bits (1272), Expect = e-140
 Identities = 254/330 (76%), Positives = 254/330 (76%), Gaps = 48/330 (14%)

Query: 1   MNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFL----------- 49
           MNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFL           
Sbjct: 6   MNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQIGSPH 65

Query: 50  -------------------------------------NFSAPYSPYALNQEADVSGGYPQ 72
                                                NFSAPYSPYALNQEADVSGGYPQ
Sbjct: 66  HHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQ 125

Query: 73  CAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA 132
           CAPAVYSGNLSSPMV       GYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA
Sbjct: 126 CAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA 185

Query: 133 SHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE 192
           SHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE
Sbjct: 186 SHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE 245

Query: 193 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE 252
           KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE
Sbjct: 246 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE 305

Query: 253 KAXXXXXXXXXXXXXXXXXXXXXDTLTTSH 282
           KA                     DTLTTSH
Sbjct: 306 KAEESSEKSSSSPCVPSPGSSTSDTLTTSH 335



>gi|123271|sp|P14653|HXB1_HUMAN   Homeobox protein Hox-B1 (Hox-2I)
          Length = 301

 Score =  181 bits (458), Expect = 3e-46
 Identities = 124/288 (43%), Positives = 151/288 (52%), Gaps = 48/288 (16%)

Query: 1   MNSFLEYPILSSGDSGTCSARAYPSDHRITTF-QSCAVSANSCGGDDRF-LNFSAP---- 54
           MNSFLEYP+ + G S      AY +    T+F  S A + +S   + R+    S+P    
Sbjct: 6   MNSFLEYPLCNRGPS------AYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQ 59

Query: 55  YSPYALNQEADVSG-GYPQCAPAVYSGNLSSPM-------------------------VX 88
            S Y   Q     G  +P  AP+ Y+    SP                            
Sbjct: 60  NSGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQ 119

Query: 89  XXXXXXGYAGGAVGSPQY--IHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETS 146
                 GY  G  G   Y   H  YG E  +     Y + L     S  +    P+   +
Sbjct: 120 LGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLL-----SEDKETPCPSEPNT 174

Query: 147 SPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARR 206
             A+TFDWMKVKRNPPKT KV E G LG P+ +RTNFTT+QLTELEKEFHFNKYL+RARR
Sbjct: 175 PTARTFDWMKVKRNPPKTAKVSEPG-LGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARR 233

Query: 207 VEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKA 254
           VEIAA+L+LNETQVKIWFQNRRMKQKKRE+EG     P  PPG  ++A
Sbjct: 234 VEIAATLELNETQVKIWFQNRRMKQKKREREG--GRVPPAPPGCPKEA 279



>gi|17378648|sp|Q9GZZ0|HXD1_HUMAN   Homeobox protein Hox-D1
          Length = 328

 Score =  156 bits (395), Expect = 6e-39
 Identities = 104/222 (46%), Positives = 122/222 (54%), Gaps = 21/222 (9%)

Query: 36  AVSANSCGGDDRFLNFSAPYS-PYALNQEADVSGGYPQCAP-AVYSGN---LSSPMVXXX 90
           A +A + G D  FL     Y  P  L + AD  G +   A  AV+SG    L S  V   
Sbjct: 96  APAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYA 155

Query: 91  XXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQ 150
                    A        H    +  S A  TY  S+SP            AS   +   
Sbjct: 156 AFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSP------------ASGLPAAFS 203

Query: 151 TFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIA 210
           TF+WMKVKRN  K GK+ EYG     +A+RTNF+TKQLTELEKEFHFNKYLTRARR+EIA
Sbjct: 204 TFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIA 263

Query: 211 ASLQLNETQVKIWFQNRRMKQKKREKEGLL----PISPATPP 248
             L LN+TQVKIWFQNRRMKQKKRE+EGLL    P++P   P
Sbjct: 264 NCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLP 305



>gi|20141491|sp|P09016|HXD4_HUMAN   Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13)
          Length = 255

 Score = 94.7 bits (234), Expect = 3e-20
 Identities = 55/111 (49%), Positives = 67/111 (60%), Gaps = 14/111 (12%)

Query: 132 ASHQEACRSPASETS--SPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFTT 185
           A  Q   + P S T+   PA  + WMK       NP  TG        G+P   RT +T 
Sbjct: 112 AYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTG--------GEPKRSRTAYTR 163

Query: 186 KQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           +Q+ ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK  K
Sbjct: 164 QQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK 214



>gi|123279|sp|P09017|HXC4_HUMAN   Homeobox protein Hox-C4 (Hox-3E) (CP19)
          Length = 264

 Score = 94.7 bits (234), Expect = 3e-20
 Identities = 60/155 (38%), Positives = 79/155 (50%), Gaps = 17/155 (10%)

Query: 104 PQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQT-----FDWMKVK 158
           P    H + ++ QSL      +  S   +    AC  PA +  S A +     + WMK  
Sbjct: 83  PAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKI 142

Query: 159 R----NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQ 214
                NP   G        G+P   R  +T +Q+ ELEKEFH+N+YLTR RR+EIA SL 
Sbjct: 143 HVSTVNPNYNG--------GEPKRSRAAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLC 194

Query: 215 LNETQVKIWFQNRRMKQKKREKEGLLPISPATPPG 249
           L+E Q+KIWFQNRRMK KK  +     +  A P G
Sbjct: 195 LSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAG 229



>gi|123270|sp|P14652|HXB2_HUMAN   Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8)
          Length = 356

 Score = 92.4 bits (228), Expect = 1e-19
 Identities = 57/133 (42%), Positives = 67/133 (50%), Gaps = 24/133 (18%)

Query: 141 PASETSSPAQTFDWMKVKRNP-----------------PKTGKVGEYGYLGQPNA----- 178
           P    + PA  F WMK K++                  P +G       LG P A     
Sbjct: 84  PPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGA 143

Query: 179 --VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
             +RT +T  QL ELEKEFHFNKYL R RRVEIAA L L E QVK+WFQNRRMK K++ +
Sbjct: 144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ 203

Query: 237 EGLLPISPATPPG 249
               P      PG
Sbjct: 204 HREPPDGEPACPG 216



>gi|6016293|sp|O43365|HXA3_HUMAN   Homeobox protein Hox-A3 (Hox-1E)
          Length = 443

 Score = 91.3 bits (225), Expect = 3e-19
 Identities = 59/137 (43%), Positives = 78/137 (56%), Gaps = 16/137 (11%)

Query: 124 NNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPK-------TGK--VGEYGYLG 174
           +N+ +P +A+      SP    +   Q F WMK  R   K       +G+   G+    G
Sbjct: 132 SNNPTPANAAKSPLLNSP----TVAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPG 187

Query: 175 QPNA--VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 232
           Q ++   RT +T+ QL ELEKEFHFN+YL R RRVE+A  L L E Q+KIWFQNRRMK K
Sbjct: 188 QASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 247

Query: 233 KREK-EGLLPISPATPP 248
           K +K +G+L  S    P
Sbjct: 248 KDQKGKGMLTSSGGQSP 264



>gi|547692|sp|P17483|HXB4_HUMAN   Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6)
          Length = 251

 Score = 90.9 bits (224), Expect = 4e-19
 Identities = 53/114 (46%), Positives = 66/114 (57%), Gaps = 21/114 (18%)

Query: 128 SPLHAS-HQEACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTN 182
           +PLH S    AC+ P          + WM+       NP   G        G+P   RT 
Sbjct: 125 NPLHPSPSHSACKEPV--------VYPWMRKVHVSTVNPNYAG--------GEPKRSRTA 168

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           +T +Q+ ELEKEFH+N+YLTR RRVEIA +L L+E Q+KIWFQNRRMK KK  K
Sbjct: 169 YTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHK 222



>gi|6166217|sp|Q00056|HXA4_HUMAN   Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4)
          Length = 320

 Score = 90.1 bits (222), Expect = 7e-19
 Identities = 51/104 (49%), Positives = 61/104 (58%), Gaps = 12/104 (11%)

Query: 137 ACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE 192
           A +SP          + WMK       NP   G        G+P   RT +T +Q+ ELE
Sbjct: 180 ADKSPLGLKGKEPVVYPWMKKIHVSAVNPSYNG--------GEPKRSRTAYTRQQVLELE 231

Query: 193 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           KEFHFN+YLTR RR+EIA +L L+E QVKIWFQNRRMK KK  K
Sbjct: 232 KEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHK 275



>gi|6166222|sp|P31249|HXD3_HUMAN   Homeobox protein Hox-D3 (Hox-4A)
          Length = 416

 Score = 89.0 bits (219), Expect = 2e-18
 Identities = 54/114 (47%), Positives = 64/114 (56%), Gaps = 9/114 (7%)

Query: 142 ASETSSPAQTFDWMKVKRNPPKT----GKVGEYGYLGQP-----NAVRTNFTTKQLTELE 192
           +S  +   Q F WMK  R   K        GE      P       VRT +T+ QL ELE
Sbjct: 135 SSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELE 194

Query: 193 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPAT 246
           KEFHFN+YL R RRVE+A  L L E Q+KIWFQNRRMK KK +K   +  SPA+
Sbjct: 195 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAS 248



>gi|17378385|sp|P31267|HXA6_HUMAN   Homeobox protein Hox-A6 (Hox-1B)
          Length = 233

 Score = 87.4 bits (215), Expect = 5e-18
 Identities = 59/158 (37%), Positives = 80/158 (50%), Gaps = 21/158 (13%)

Query: 97  AGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMK 156
           +G   G   Y+H S  Q+++       ++S     A H E      ++    +  + WM+
Sbjct: 93  SGKQRGPGDYLHFSPEQQYKP------DSSSGQGKALHDEG-----ADRKYTSPVYPWMQ 141

Query: 157 VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLN 216
            + N       G +G  G     R  +T  Q  ELEKEFHFN+YLTR RR+EIA +L L 
Sbjct: 142 -RMNSCAGAVYGSHGRRG-----RQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLT 195

Query: 217 ETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKA 254
           E Q+KIWFQNRRMK KK  K     I+   P G D +A
Sbjct: 196 ERQIKIWFQNRRMKWKKENK----LINSTQPSGEDSEA 229



>gi|6016292|sp|O43364|HXA2_HUMAN   Homeobox protein Hox-A2
          Length = 376

 Score = 87.4 bits (215), Expect = 5e-18
 Identities = 67/206 (32%), Positives = 83/206 (40%), Gaps = 36/206 (17%)

Query: 60  LNQEADVSGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLA 119
           +N E +   G+    P++     S P V             +     I   + Q   SL 
Sbjct: 1   MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSL- 59

Query: 120 LATYNNSLSPLHASHQEACRSPASETSSPAQT-------FDWMKVKRNPPKTGKVGEY-- 170
               N    P H +      SPA    SP          + WMK K+   KT  +     
Sbjct: 60  ----NPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAA 115

Query: 171 ----------------------GYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVE 208
                                 G  G    +RT +T  QL ELEKEFHFNKYL R RRVE
Sbjct: 116 AATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVE 175

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKR 234
           IAA L L E QVK+WFQNRRMK K++
Sbjct: 176 IAALLDLTERQVKVWFQNRRMKHKRQ 201



>gi|232262|sp|Q00444|HXC5_HUMAN   Homeobox protein Hox-C5 (Hox-3D) (CP11)
          Length = 222

 Score = 87.0 bits (214), Expect = 6e-18
 Identities = 48/95 (50%), Positives = 59/95 (62%), Gaps = 12/95 (12%)

Query: 143 SETSSPAQTFDWM-KVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYL 201
           S+  +P Q + WM K+  +    GK             RT++T  Q  ELEKEFHFN+YL
Sbjct: 132 SQPPAPPQIYPWMTKLHMSHETDGKRS-----------RTSYTRYQTLELEKEFHFNRYL 180

Query: 202 TRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           TR RR+EIA +L LNE Q+KIWFQNRRMK KK  K
Sbjct: 181 TRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSK 215



>gi|400000|sp|P09067|HXB5_HUMAN   Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1)
          Length = 269

 Score = 86.7 bits (213), Expect = 8e-18
 Identities = 53/117 (45%), Positives = 66/117 (56%), Gaps = 9/117 (7%)

Query: 121 ATYNNSLSPLHASHQEACRSPASETSSPAQTFDWM-KVKRNPPKTGKVGEYGYLGQPNAV 179
           A+  +S S   A  +    S A+      Q F WM K+  +   TG  G+          
Sbjct: 146 ASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLHISHDMTGPDGK--------RA 197

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT +T  Q  ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK  K
Sbjct: 198 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254



>gi|13124738|sp|P17509|HXB6_HUMAN   Homeobox protein Hox-B6 (Hox-2B) (Hox-2.2) (HU-2)
          Length = 224

 Score = 85.9 bits (211), Expect = 1e-17
 Identities = 69/221 (31%), Positives = 92/221 (41%), Gaps = 36/221 (16%)

Query: 41  SCGGDDRFLNFSAPYSPYALNQEA--------DVSGGYPQCAPAVYSGNLSSPMVXXXXX 92
           S G  D   ++ APY P     +            GGY + AP  Y     +P       
Sbjct: 29  SSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYG---PAPAFYREKE 85

Query: 93  XXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTF 152
                 GA   P +        H     +      S    + ++ C +P          +
Sbjct: 86  SACALSGADEQPPF--------HPEPRKSDCAQDKSVFGETEEQKCSTPV---------Y 128

Query: 153 DWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAAS 212
            WM+ + N   +   G  G  G     R  +T  Q  ELEKEFH+N+YLTR RR+EIA +
Sbjct: 129 PWMQ-RMNSCNSSSFGPSGRRG-----RQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHA 182

Query: 213 LQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEK 253
           L L E Q+KIWFQNRRMK KK  K  LL  S  +    +EK
Sbjct: 183 LCLTERQIKIWFQNRRMKWKKESK--LLSASQLSAEEEEEK 221



>gi|3915721|sp|P31268|HXA7_HUMAN   Homeobox protein Hox-A7 (Hox-1A) (Hox 1.1)
          Length = 230

 Score = 84.7 bits (208), Expect = 3e-17
 Identities = 65/190 (34%), Positives = 89/190 (46%), Gaps = 38/190 (20%)

Query: 67  SGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNS 126
           +G +    P +Y  N++SP+        GY  GA         +YG    +L  A+Y+ +
Sbjct: 44  AGAFASTVPGLY--NVNSPLYQSPFAS-GYGLGA--------DAYG----NLPCASYDQN 88

Query: 127 LSPLHASHQEACRSPASE------TSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVR 180
           +  L +   +       E        +  + + WM+      K G              R
Sbjct: 89  IPGLCSDLAKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRG--------------R 134

Query: 181 TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK-EGL 239
             +T  Q  ELEKEFHFN+YLTR RR+EIA +L L E Q+KIWFQNRRMK KK  K EG 
Sbjct: 135 QTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEG- 193

Query: 240 LPISPATPPG 249
            P + A P G
Sbjct: 194 -PTAAAAPEG 202



>gi|45644931|sp|P50219|HLXB9_HUMAN   Homeobox protein HB9
          Length = 403

 Score = 84.3 bits (207), Expect = 4e-17
 Identities = 62/158 (39%), Positives = 79/158 (50%), Gaps = 16/158 (10%)

Query: 95  GYAGGAVGSPQ----YIHHSYGQEHQSLA--LATYNNSLSPLHASHQEACRS-PASETSS 147
           G A G  G P     Y H  YG    + A  LA  + +LS  +   Q A  + PA     
Sbjct: 146 GGAQGGAGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKL 205

Query: 148 PAQTFD---WMKVKR------NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFN 198
            A TF    W++           P      +   LG+    RT FT++QL ELE +F  N
Sbjct: 206 GAGTFQLDQWLRASTAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLN 265

Query: 199 KYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           KYL+R +R E+A SL L ETQVKIWFQNRRMK K+ +K
Sbjct: 266 KYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 303



>gi|13124737|sp|P13378|HXD8_HUMAN   Homeobox protein Hox-D8 (Hox-4E) (Hox-5.4)
          Length = 290

 Score = 83.6 bits (205), Expect = 7e-17
 Identities = 44/101 (43%), Positives = 59/101 (58%), Gaps = 13/101 (12%)

Query: 143 SETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLT 202
           +++SSP+Q F WM+ +  P +                R  ++  Q  ELEKEF FN YLT
Sbjct: 177 NQSSSPSQMFPWMRPQAAPGR-------------RRGRQTYSRFQTLELEKEFLFNPYLT 223

Query: 203 RARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPIS 243
           R RR+E++ +L L E QVKIWFQNRRMK KK   +   P+S
Sbjct: 224 RKRRIEVSHALALTERQVKIWFQNRRMKWKKENNKDKFPVS 264



>gi|123268|sp|P14651|HXB3_HUMAN   Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7)
          Length = 431

 Score = 83.6 bits (205), Expect = 7e-17
 Identities = 42/68 (61%), Positives = 49/68 (72%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT +T+ QL ELEKEFHFN+YL R RRVE+A  L L+E Q+KIWFQNRRMK KK +K   
Sbjct: 192 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKG 251

Query: 240 LPISPATP 247
           L  S   P
Sbjct: 252 LASSSGGP 259



>gi|52788238|sp|P20719|HXA5_HUMAN   Homeobox protein Hox-A5 (Hox-1C)
          Length = 270

 Score = 83.6 bits (205), Expect = 7e-17
 Identities = 47/111 (42%), Positives = 61/111 (54%), Gaps = 10/111 (9%)

Query: 128 SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNA--VRTNFTT 185
           +P  +    A   P+    +  Q + WM+             +  +G P     RT +T 
Sbjct: 153 APASSEQASAQSEPSPAPPAQPQIYPWMRKLHI--------SHDNIGGPEGKRARTAYTR 204

Query: 186 KQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
            Q  ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK  K
Sbjct: 205 YQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 255



>gi|1708540|sp|P52945|IPF1_HUMAN   Insulin promoter factor-1 (IPF-1) (Pancreas/duodenum homeobox-1)
           (PDX-1) (Islet/duodenum homeobox-1) (IDX-1)
           (Somatostatin transactivating factor-1) (STF-1) (Insulin
           upstream factor-1) (IUF-1) (Glucose-sensitive factor)
           (GSF)
          Length = 283

 Score = 83.2 bits (204), Expect = 9e-17
 Identities = 44/87 (50%), Positives = 52/87 (59%), Gaps = 3/87 (3%)

Query: 152 FDWMKVKRNPPKTGKVGEYGYLGQPNA---VRTNFTTKQLTELEKEFHFNKYLTRARRVE 208
           F WMK  +     G+     Y  +P      RT +T  QL ELEKEF FNKY++R RRVE
Sbjct: 119 FPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 178

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKRE 235
           +A  L L E  +KIWFQNRRMK KK E
Sbjct: 179 LAVMLNLTERHIKIWFQNRRMKWKKEE 205



>gi|20141282|sp|Q99626|CDX2_HUMAN   Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3)
          Length = 313

 Score = 81.6 bits (200), Expect = 3e-16
 Identities = 69/232 (29%), Positives = 100/232 (43%), Gaps = 16/232 (6%)

Query: 23  YPSDHRITTFQSCAVSANSCGGDDRFLNFSAPY-SPYALNQEADVSGGYPQCAPAVYSG- 80
           YP         + A +AN         ++ A Y +P   +      GG    A AV  G 
Sbjct: 37  YPDYGGYHVAAAAAAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGL 96

Query: 81  NLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRS 140
           N  SP         GY+  A   P + H  +   H + A +  +  L  L+        +
Sbjct: 97  NGGSP-----AAAMGYSSPADYHPHH-HPHHHPHHPAAAPSCASGLLQTLNPGPPGPAAT 150

Query: 141 PASETSSPA----QTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFH 196
            A+E  SP        +WM+     P    +G        +  R  +T  Q  ELEKEFH
Sbjct: 151 AAAEQLSPGGQRRNLCEWMR----KPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFH 206

Query: 197 FNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPP 248
           +++Y+T  R+ E+AA+L L+E QVKIWFQNRR K++K  K+ L       PP
Sbjct: 207 YSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKLQQQQQQQPP 258



>gi|123255|sp|P09629|HXB7_HUMAN   Homeobox protein Hox-B7 (Hox-2C) (HHO.C1)
          Length = 217

 Score = 81.3 bits (199), Expect = 3e-16
 Identities = 58/205 (28%), Positives = 85/205 (41%), Gaps = 35/205 (17%)

Query: 52  SAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMVXXXXXXXG-------YAGGAVGSP 104
           +A +S Y  +     +G +P+     ++ N   P                 Y GG   + 
Sbjct: 8   NALFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAGSMQGLYPGGGGMAG 67

Query: 105 QYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFD----------- 153
           Q     Y   +  L  +++N   +P   +    C   +++ +   +  D           
Sbjct: 68  QSAAGVYAAGY-GLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRI 126

Query: 154 --WMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAA 211
             WM+      K G              R  +T  Q  ELEKEFH+N+YLTR RR+EIA 
Sbjct: 127 YPWMRSSGTDRKRG--------------RQTYTRYQTLELEKEFHYNRYLTRRRRIEIAH 172

Query: 212 SLQLNETQVKIWFQNRRMKQKKREK 236
           +L L E Q+KIWFQNRRMK KK  K
Sbjct: 173 TLCLTERQIKIWFQNRRMKWKKENK 197



>gi|13124745|sp|P31273|HXC8_HUMAN   Homeobox protein Hox-C8 (Hox-3A)
          Length = 242

 Score = 80.5 bits (197), Expect = 6e-16
 Identities = 49/131 (37%), Positives = 69/131 (52%), Gaps = 16/131 (12%)

Query: 111 YGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEY 170
           YG + Q  ++  Y +  S  + +  E  +   ++ SSP+  F WM+      ++G     
Sbjct: 100 YGAQ-QEASVVQYPDCKSSANTNSSEG-QGHLNQNSSPSLMFPWMRPHAPGRRSG----- 152

Query: 171 GYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK 230
                    R  ++  Q  ELEKEF FN YLTR RR+E++ +L L E QVKIWFQNRRMK
Sbjct: 153 ---------RQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMK 203

Query: 231 QKKREKEGLLP 241
            KK   +  LP
Sbjct: 204 WKKENNKDKLP 214



>gi|20141493|sp|P09630|HXC6_HUMAN   Homeobox protein Hox-C6 (Hox-3C) (HHO.C8) (CP25)
          Length = 235

 Score = 80.5 bits (197), Expect = 6e-16
 Identities = 51/137 (37%), Positives = 67/137 (48%), Gaps = 11/137 (8%)

Query: 102 GSPQYIHHSYGQEHQSLALAT-----YNNSLSPLHASHQEACRSPASETSSPAQTFDWMK 156
           G   Y  +S+ QE   L+        +N   S       E  R+   +  +  Q + WM+
Sbjct: 68  GPYDYGSNSFYQEKDMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQ 127

Query: 157 VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLN 216
                 +       GY       R  ++  Q  ELEKEFHFN+YLTR RR+EIA +L L 
Sbjct: 128 ------RMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLT 181

Query: 217 ETQVKIWFQNRRMKQKK 233
           E Q+KIWFQNRRMK KK
Sbjct: 182 ERQIKIWFQNRRMKWKK 198



>gi|12644308|sp|P52951|GBX2_HUMAN   Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox
           protein 2)
          Length = 348

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 39/77 (50%), Positives = 51/77 (66%)

Query: 157 VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLN 216
           ++  PP +G  G     G+    RT FT++QL ELEKEFH  KYL+   R +IA +L+L+
Sbjct: 228 LEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLS 287

Query: 217 ETQVKIWFQNRRMKQKK 233
           E QVKIWFQNRR K K+
Sbjct: 288 EVQVKIWFQNRRAKWKR 304



>gi|1345720|sp|P47902|CDX1_HUMAN   Homeobox protein CDX-1 (Caudal-type homeobox protein 1)
          Length = 265

 Score = 78.2 bits (191), Expect = 3e-15
 Identities = 44/109 (40%), Positives = 61/109 (55%), Gaps = 6/109 (5%)

Query: 140 SPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNK 199
           SP ++  +P   ++WM   R     G  G  G     +  R  +T  Q  ELEKEFH+++
Sbjct: 124 SPGAQRPTP---YEWM---RRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSR 177

Query: 200 YLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPP 248
           Y+T  R+ E+AA+L L E QVKIWFQNRR K++K  K+      P  PP
Sbjct: 178 YITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPPQPP 226



>gi|20141506|sp|P17481|HXB8_HUMAN   Homeobox protein Hox-B8 (Hox-2D) (Hox-2.4)
          Length = 243

 Score = 77.8 bits (190), Expect = 4e-15
 Identities = 44/102 (43%), Positives = 56/102 (54%), Gaps = 13/102 (12%)

Query: 142 ASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYL 201
           + ++ SP Q F WM+     P+       G        R  ++  Q  ELEKEF FN YL
Sbjct: 125 SEQSPSPTQLFPWMR-----PQAAAGRRRG--------RQTYSRYQTLELEKEFLFNPYL 171

Query: 202 TRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPIS 243
           TR RR+E++ +L L E QVKIWFQNRRMK KK   +   P S
Sbjct: 172 TRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSS 213



>gi|20141507|sp|P17482|HXB9_HUMAN   Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5)
          Length = 250

 Score = 77.0 bits (188), Expect = 6e-15
 Identities = 41/80 (51%), Positives = 47/80 (58%)

Query: 158 KRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNE 217
           K  P +T     + +       R  +T  Q  ELEKEF FN YLTR RR E+A  L L+E
Sbjct: 167 KERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSE 226

Query: 218 TQVKIWFQNRRMKQKKREKE 237
            QVKIWFQNRRMK KK  KE
Sbjct: 227 RQVKIWFQNRRMKMKKMNKE 246



>gi|27923786|sp|Q9H4S2|GSHI_HUMAN   Homeobox protein GSH-1
          Length = 264

 Score = 76.6 bits (187), Expect = 8e-15
 Identities = 51/135 (37%), Positives = 68/135 (50%), Gaps = 19/135 (14%)

Query: 105 QYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPA---QTFDWMKVKRNP 161
           QY H   G++H ++       S    H     A  +   +TS P    + F  + V  + 
Sbjct: 89  QYCHAPLGRQHSAV-------SPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSS 141

Query: 162 PKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVK 221
            +         L     +RT FT+ QL ELE+EF  N YL+R RR+EIA  L L+E QVK
Sbjct: 142 NQ---------LPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVK 192

Query: 222 IWFQNRRMKQKKREK 236
           IWFQNRR+K KK  K
Sbjct: 193 IWFQNRRVKHKKEGK 207



>gi|20138327|sp|Q9BZM3|GSH2_HUMAN   Homeobox protein GSH-2
          Length = 304

 Score = 75.9 bits (185), Expect = 1e-14
 Identities = 37/58 (63%), Positives = 44/58 (75%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           +RT FT+ QL ELE+EF  N YL+R RR+EIA  L L+E QVKIWFQNRR+K KK  K
Sbjct: 205 MRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 262



>gi|1709078|sp|P50221|MEOX1_HUMAN   Homeobox protein MOX-1 (Mesenchyme homeobox 1)
          Length = 254

 Score = 75.1 bits (183), Expect = 2e-14
 Identities = 40/65 (61%), Positives = 47/65 (72%), Gaps = 2/65 (3%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT FT +QL ELE EF  + YLTR RR EIA +L L+E QVK+WFQNRRMK K+   +G 
Sbjct: 175 RTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR--VKGG 232

Query: 240 LPISP 244
            PISP
Sbjct: 233 QPISP 237



>gi|20141537|sp|P31274|HXC9_HUMAN   Homeobox protein Hox-C9 (Hox-3B)
          Length = 260

 Score = 74.7 bits (182), Expect = 3e-14
 Identities = 38/58 (65%), Positives = 40/58 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           R  +T  Q  ELEKEF FN YLTR RR E+A  L L E QVKIWFQNRRMK KK  KE
Sbjct: 196 RCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKE 253



>gi|123286|sp|P28356|HXD9_HUMAN   Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2)
          Length = 342

 Score = 74.7 bits (182), Expect = 3e-14
 Identities = 38/58 (65%), Positives = 40/58 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           R  +T  Q  ELEKEF FN YLTR RR E+A  L L E QVKIWFQNRRMK KK  KE
Sbjct: 279 RCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKE 336



>gi|123289|sp|P28358|HXD10_HUMAN   Homeobox protein Hox-D10 (Hox-4D) (Hox-4E)
          Length = 340

 Score = 73.9 bits (180), Expect = 5e-14
 Identities = 42/94 (44%), Positives = 50/94 (53%), Gaps = 16/94 (17%)

Query: 144 ETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTR 203
           E  S   T +W+  K    K                R  +T  Q  ELEKEF FN YLTR
Sbjct: 250 EIKSDTPTSNWLTAKSGRKK----------------RCPYTKHQTLELEKEFLFNMYLTR 293

Query: 204 ARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
            RR+EI+ S+ L + QVKIWFQNRRMK KK  +E
Sbjct: 294 ERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRE 327



>gi|13124743|sp|P31260|HXA10_HUMAN   Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL)
          Length = 393

 Score = 73.6 bits (179), Expect = 7e-14
 Identities = 36/58 (62%), Positives = 42/58 (72%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           R  +T  Q  ELEKEF FN YLTR RR+EI+ S+ L + QVKIWFQNRRMK KK  +E
Sbjct: 323 RCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRE 380



>gi|20141612|sp|Q9NYD6|HXC10_HUMAN   Homeobox protein Hox-C10
          Length = 342

 Score = 73.2 bits (178), Expect = 9e-14
 Identities = 68/215 (31%), Positives = 90/215 (41%), Gaps = 32/215 (14%)

Query: 24  PSDHRITTFQSCAVSANSCGGDDRFLNFSAPYSPYA-LNQEADVSGGYPQCAPAVYSGNL 82
           PS +R +   S       C G +   +F AP+   A LN  A+               +L
Sbjct: 146 PSYYRASPSYSALDKTPHCSGAN---DFEAPFEQRASLNPRAE---------------HL 187

Query: 83  SSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPA 142
            SP +          GG V  P+    S  Q      + T   SL+    S  E+ +  A
Sbjct: 188 ESPQL----------GGKVSFPE-TPKSDSQTPSPNEIKT-EQSLAGPKGSPSESEKERA 235

Query: 143 SETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLT 202
               S   T D  + K         G +         R  +T  Q  ELEKEF FN YLT
Sbjct: 236 KAADSSPDTSD-NEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLT 294

Query: 203 RARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           R RR+EI+ ++ L + QVKIWFQNRRMK KK  +E
Sbjct: 295 RERRLEISKTINLTDRQVKIWFQNRRMKLKKMNRE 329



>gi|6166219|sp|P31269|HXA9_HUMAN   Homeobox protein Hox-A9 (Hox-1G)
          Length = 272

 Score = 73.2 bits (178), Expect = 9e-14
 Identities = 37/58 (63%), Positives = 40/58 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           R  +T  Q  ELEKEF FN YLTR RR E+A  L L E QVKIWFQNRRMK KK  K+
Sbjct: 210 RCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKD 267



>gi|1709079|sp|P50222|MEOX2_HUMAN   Homeobox protein MOX-2 (Mesenchyme homeobox 2) (Growth
           arrest-specific homeobox)
          Length = 303

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 35/59 (59%), Positives = 42/59 (71%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           +P   RT FT +Q+ ELE EF  + YLTR RR EIA +L L E QVK+WFQNRRMK K+
Sbjct: 185 KPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKR 243



>gi|57015304|sp|Q04741|EMX1_HUMAN   Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty
           spiracles-like protein 1)
          Length = 257

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 61/212 (28%), Positives = 89/212 (41%), Gaps = 37/212 (17%)

Query: 54  PYSPYALNQ------EADVSGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYI 107
           P  P ALN       EA    G+P  A A    +L             Y G  +  P+ +
Sbjct: 44  PLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRSL-------------YGGPELVFPEAM 90

Query: 108 HHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKR-------- 159
           +H     H +  L       SPL   H        ++   P   + W+   R        
Sbjct: 91  NHPALTVHPAHQLGA-----SPLQPPHSFF----GAQHRDPLHFYPWVLRNRFFGHRFQA 141

Query: 160 -NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNET 218
            + P+ G +    +  +P  +RT F+  QL  LE+ F  N Y+  A R ++A SL L+ET
Sbjct: 142 SDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSET 201

Query: 219 QVKIWFQNRRMKQKKREKEGLLPISPATPPGN 250
           QVK+WFQNRR K K+++ E   P S     G+
Sbjct: 202 QVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS 233



>gi|12230077|sp|Q14549|GBX1_HUMAN   Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox
           protein 1)
          Length = 139

 Score = 71.6 bits (174), Expect = 3e-13
 Identities = 35/60 (58%), Positives = 44/60 (73%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT FT++QL ELEKEFH  KYL+   R +IA +L+L+E QVKIWFQNRR K K+
Sbjct: 35  GKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 94



>gi|23503066|sp|P28360|MSX1_HUMAN   Homeobox protein MSX-1 (Hox-7)
          Length = 297

 Score = 71.2 bits (173), Expect = 4e-13
 Identities = 44/108 (40%), Positives = 54/108 (50%), Gaps = 18/108 (16%)

Query: 141 PASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKY 200
           PA   S PA T    K  R P                  RT FTT QL  LE++F   +Y
Sbjct: 149 PARRLSPPACTLRKHKTNRKP------------------RTPFTTAQLLALERKFRQKQY 190

Query: 201 LTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPP 248
           L+ A R E ++SL L ETQVKIWFQNRR K K+ ++  L  +  A  P
Sbjct: 191 LSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKP 238



>gi|1352398|sp|P49640|EVX1_HUMAN   Homeobox even-skipped homolog protein 1 (EVX-1)
          Length = 407

 Score = 71.2 bits (173), Expect = 4e-13
 Identities = 36/73 (49%), Positives = 47/73 (64%), Gaps = 1/73 (1%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           Q    RT FT +Q+  LEKEF+   Y++R RR E+AA+L L ET +K+WFQNRRMK K++
Sbjct: 182 QMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQ 241

Query: 235 EKEGLLPISPATP 247
                 P  PA P
Sbjct: 242 RLAMTWP-HPADP 253



>gi|12231013|sp|Q03828|EVX2_HUMAN   Homeobox even-skipped homolog protein 2 (EVX-2)
          Length = 476

 Score = 70.9 bits (172), Expect = 5e-13
 Identities = 36/73 (49%), Positives = 47/73 (64%), Gaps = 1/73 (1%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           Q    RT FT +Q+  LEKEF+   Y++R RR E+AA+L L ET +K+WFQNRRMK K++
Sbjct: 187 QVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQ 246

Query: 235 EKEGLLPISPATP 247
                 P  PA P
Sbjct: 247 RLAMSWP-HPADP 258



>gi|20532295|sp|Q9UIW0|VAX2_HUMAN   Ventral anterior homeobox 2
          Length = 290

 Score = 70.1 bits (170), Expect = 8e-13
 Identities = 34/67 (50%), Positives = 43/67 (64%)

Query: 173 LGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 232
           L +P   RT+FT +QL  LE EF   +Y+    R E+A  L L+ETQVK+WFQNRR KQK
Sbjct: 99  LDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQK 158

Query: 233 KREKEGL 239
           K +   L
Sbjct: 159 KDQSRDL 165



>gi|3023467|sp|O14627|CDX4_HUMAN   Homeobox protein CDX-4 (Caudal-type homeobox protein 4)
          Length = 284

 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 47/112 (41%), Positives = 62/112 (55%), Gaps = 12/112 (10%)

Query: 126 SLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTT 185
           SL P  A   +A  SP+    SP   + WM+      KT +V   G        R  +T 
Sbjct: 135 SLVPTDAGAAKAS-SPSRSRHSP---YAWMR------KTVQVT--GKTRTKEKYRVVYTD 182

Query: 186 KQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
            Q  ELEKEFH N+Y+T  R+ E+A +L L+E QVKIWFQNRR K++K  K+
Sbjct: 183 HQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKK 234



>gi|29336920|sp|Q9BZE3|BARH1_HUMAN   BarH-like 1 homeobox protein (FKSG31 protein)
          Length = 327

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 48/132 (36%), Positives = 66/132 (50%), Gaps = 11/132 (8%)

Query: 119 ALATYNNSLSP--------LHASHQEACRSPASETSSPAQTFDWMKVKRNPPK---TGKV 167
           A A Y++S  P        L A   E  R    ++ S A +    KVK    +   + + 
Sbjct: 110 ACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDREISSSRD 169

Query: 168 GEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNR 227
                L +P   RT FT  QL +LE+ F   KYL+   R+E+AASL L +TQVK W+QNR
Sbjct: 170 SPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNR 229

Query: 228 RMKQKKREKEGL 239
           R K K++   GL
Sbjct: 230 RTKWKRQTAVGL 241



>gi|13959687|sp|P35548|MSX2_HUMAN   Homeobox protein MSX-2 (Hox-8)
          Length = 267

 Score = 69.3 bits (168), Expect = 1e-12
 Identities = 35/69 (50%), Positives = 45/69 (65%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT FTT QL  LE++F   +YL+ A R E ++SL L ETQVKIWFQNRR K K+ ++  L
Sbjct: 146 RTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAEL 205

Query: 240 LPISPATPP 248
             +  A  P
Sbjct: 206 EKLKMAAKP 214



>gi|2506529|sp|Q07687|DLX2_HUMAN   Homeobox protein DLX-2
          Length = 328

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 57/161 (35%), Positives = 75/161 (46%), Gaps = 18/161 (11%)

Query: 98  GGAVGSPQYIHHSYGQEHQSLALATYNNSLS-PLHASHQEACRSPASETSSPAQTFDWMK 156
           GG  GSP     SY  +   L    Y+   S  L  +      +P   +SSPA       
Sbjct: 77  GGGGGSPYAHMGSYQYQASGLNNVPYSAKSSYDLGYTAAYTSYAPYGTSSSPANN----- 131

Query: 157 VKRNPPKTGKVGEYGYL-GQPNAVR---TNFTTKQLTELEKEFHFNKYLTRARRVEIAAS 212
               P K     E   + G+P  VR   T +++ QL  L++ F   +YL    R E+AAS
Sbjct: 132 ---EPEKEDLEPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAAS 188

Query: 213 LQLNETQVKIWFQNRRMKQKKREKEGLLPI-----SPATPP 248
           L L +TQVKIWFQNRR K KK  K G +P      + A+PP
Sbjct: 189 LGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASASPP 229



>gi|14917010|sp|Q05925|HME1_HUMAN   Homeobox protein engrailed-1 (Hu-En-1)
          Length = 392

 Score = 68.9 bits (167), Expect = 2e-12
 Identities = 63/207 (30%), Positives = 87/207 (42%), Gaps = 25/207 (12%)

Query: 35  CAVSANSCGGDDRFLNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPMVXXXXXXX 94
           CA  AN CG  D     S P +  A   +A         A A  +   ++          
Sbjct: 171 CAPDAN-CGPPDG----SQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGG 225

Query: 95  GYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSS--PAQTF 152
           G +GG  GSP      Y  EH + A+    +           A   P  +T S  P    
Sbjct: 226 GGSGGGAGSPGAQGTKY-PEHGNPAILLMGS-----------ANGGPVVKTDSQQPLVWP 273

Query: 153 DWMKVKR------NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARR 206
            W+   R      + P+T K+ +     +    RT FT +QL  L+ EF  N+Y+T  RR
Sbjct: 274 AWVYCTRYSDRPSSGPRTRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRR 333

Query: 207 VEIAASLQLNETQVKIWFQNRRMKQKK 233
             +A  L LNE+Q+KIWFQN+R K KK
Sbjct: 334 QTLAQELSLNESQIKIWFQNKRAKIKK 360



>gi|3287858|sp|O43248|HXC11_HUMAN   Homeobox protein Hox-C11
          Length = 304

 Score = 67.8 bits (164), Expect = 4e-12
 Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 14/101 (13%)

Query: 144 ETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTN-----FTTKQLTELEKEFHFN 198
           E ++P+ +     V + P K            PNA RT      ++  Q+ ELE+EF FN
Sbjct: 204 ENTNPSSSGSAHSVAKEPAKGAA---------PNAPRTRKKRCPYSKFQIRELEREFFFN 254

Query: 199 KYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
            Y+ + +R++++  L L + QVKIWFQNRRMK+KK  ++ L
Sbjct: 255 VYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRL 295



>gi|399982|sp|P31314|TLX1_HUMAN   T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (TCL-3
           proto-oncogene)
          Length = 330

 Score = 67.8 bits (164), Expect = 4e-12
 Identities = 37/90 (41%), Positives = 50/90 (55%), Gaps = 3/90 (3%)

Query: 151 TFDWMKVKRNPPK---TGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRV 207
           TF WM+  R   K   TG   +     +    RT+FT  Q+ ELEK FH  KYL  A R 
Sbjct: 173 TFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERA 232

Query: 208 EIAASLQLNETQVKIWFQNRRMKQKKREKE 237
            +A +L++ + QVK WFQNRR K +++  E
Sbjct: 233 ALAKALKMTDAQVKTWFQNRRTKWRRQTAE 262



>gi|12644227|sp|P35452|HXD12_HUMAN   Homeobox protein Hox-D12 (Hox-4H)
          Length = 275

 Score = 67.4 bits (163), Expect = 5e-12
 Identities = 33/76 (43%), Positives = 48/76 (63%)

Query: 158 KRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNE 217
           KR P   G+    G  G+    R  +T +Q+ ELE EF  N+++ R +R E++  L L++
Sbjct: 189 KRCPCSPGRPAVGGGPGEARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSD 248

Query: 218 TQVKIWFQNRRMKQKK 233
            QVKIWFQNRRMK+K+
Sbjct: 249 QQVKIWFQNRRMKKKR 264



>gi|3913487|sp|O60479|DLX3_HUMAN   Homeobox protein DLX-3
          Length = 287

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 54/172 (31%), Positives = 81/172 (47%), Gaps = 22/172 (12%)

Query: 99  GAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETS------------ 146
           G   +PQ+ ++S     Q++   TY++  + L+        SP SE +            
Sbjct: 41  GYYSAPQHDYYSGQPYGQTVNPYTYHHQFN-LNGLAGTGAYSPKSEYTYGASYRQYGAYR 99

Query: 147 -SPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVR---TNFTTKQLTELEKEFHFNKYLT 202
             P    D + VK  P    ++      G+P  VR   T +++ QL  L++ F   +YL 
Sbjct: 100 EQPLPAQDPVSVKEEPEAEVRMVN----GKPKKVRKPRTIYSSYQLAALQRRFQKAQYLA 155

Query: 203 RARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKA 254
              R E+AA L L +TQVKIWFQNRR K KK  K G +P+   +P  +D  A
Sbjct: 156 LPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLE-HSPNNSDSMA 206



>gi|21903415|sp|P19622|HME2_HUMAN   Homeobox protein engrailed-2 (Hu-En-2)
          Length = 333

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 36/76 (47%), Positives = 44/76 (57%), Gaps = 11/76 (14%)

Query: 158 KRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNE 217
           K+NP K  K             RT FT +QL  L+ EF  N+YLT  RR  +A  L LNE
Sbjct: 237 KKNPNKEDK-----------RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNE 285

Query: 218 TQVKIWFQNRRMKQKK 233
           +Q+KIWFQN+R K KK
Sbjct: 286 SQIKIWFQNKRAKIKK 301



>gi|12644203|sp|P31277|HXD11_HUMAN   Homeobox protein Hox-D11 (Hox-4F)
          Length = 338

 Score = 66.6 bits (161), Expect = 9e-12
 Identities = 29/60 (48%), Positives = 43/60 (71%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           R  +T  Q+ ELE+EF FN Y+ + +R++++  L L + QVKIWFQNRRMK+KK  ++ L
Sbjct: 270 RCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRL 329



>gi|6016210|sp|P78367|NK32_HUMAN   Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1)
          Length = 333

 Score = 66.2 bits (160), Expect = 1e-11
 Identities = 34/67 (50%), Positives = 46/67 (68%), Gaps = 1/67 (1%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG- 238
           R  F+  Q+ ELE+ F+  +YL+   R ++AASL+L ETQVKIWFQNRR K K+R+    
Sbjct: 210 RAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAAD 269

Query: 239 LLPISPA 245
           LL  +PA
Sbjct: 270 LLASAPA 276



>gi|14194481|sp|Q9HBU1|BARX1_HUMAN   Homeobox protein BarH-like 1
          Length = 225

 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 36/74 (48%), Positives = 45/74 (60%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT FT  QL  LEK F   KYL+   R+++A SL L++ QVK W+QNRRMK KK   +G 
Sbjct: 117 RTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGG 176

Query: 240 LPISPATPPGNDEK 253
              SP  P G  +K
Sbjct: 177 GLESPTKPKGRPKK 190



>gi|19862512|sp|Q04743|EMX2_HUMAN   Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty
           spiracles-like protein 2)
          Length = 252

 Score = 65.1 bits (157), Expect = 3e-11
 Identities = 33/66 (50%), Positives = 43/66 (65%), Gaps = 2/66 (3%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRR--MKQK 232
           +P  +RT F+  QL  LE  F  N Y+  A R ++A SL L ETQVK+WFQNRR   K++
Sbjct: 153 KPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ 212

Query: 233 KREKEG 238
           K E+EG
Sbjct: 213 KLEEEG 218



>gi|12644329|sp|P56178|DLX5_HUMAN   Homeobox protein DLX-5
          Length = 289

 Score = 64.7 bits (156), Expect = 3e-11
 Identities = 71/241 (29%), Positives = 96/241 (39%), Gaps = 55/241 (22%)

Query: 8   PILSSGDSG----TCSARAYPSDHRITTFQSCAVSANSCGGDDRFLNFSAPYSPYALNQE 63
           P + SGD      T +A  +PS    T  +S A  ++              YSP      
Sbjct: 10  PSIRSGDFQAPFQTSAAMHHPSQESPTLPESSATDSDY-------------YSP------ 50

Query: 64  ADVSGGYPQ--CAPAVYS-GNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLAL 120
              +GG P   C+P   S G   +P         G AG +  +  Y  +SY   +     
Sbjct: 51  ---TGGAPHGYCSPTSASYGKALNPYQYQYHGVNGSAG-SYPAKAYADYSYASSYHQYGG 106

Query: 121 ATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVR 180
           A YN   S        A   P  E + P    +   V   P K  K             R
Sbjct: 107 A-YNRVPS--------ATNQPEKEVTEP----EVRMVNGKPKKVRKP------------R 141

Query: 181 TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLL 240
           T +++ QL  L++ F   +YL    R E+AASL L +TQVKIWFQN+R K KK  K G +
Sbjct: 142 TIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMKNGEM 201

Query: 241 P 241
           P
Sbjct: 202 P 202



>gi|13124744|sp|P31270|HXA11_HUMAN   Homeobox protein Hox-A11 (Hox-1I)
          Length = 313

 Score = 64.3 bits (155), Expect = 4e-11
 Identities = 28/60 (46%), Positives = 43/60 (71%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           R  +T  Q+ ELE+EF F+ Y+ + +R++++  L L + QVKIWFQNRRMK+KK  ++ L
Sbjct: 245 RCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRL 304



>gi|13431329|sp|Q9UMQ3|BARX2_HUMAN   Homeobox protein BarH-like 2
          Length = 254

 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 36/79 (45%), Positives = 47/79 (59%), Gaps = 1/79 (1%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           +P   RT FT  QL  LEK+F   KYL+   R+++A SL L + QVK W+QNRRMK KK 
Sbjct: 107 KPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKM 166

Query: 235 EKEGLLPISPATPPGNDEK 253
             +G    +P  P G  +K
Sbjct: 167 VLKGGQE-APTKPKGRPKK 184



>gi|47117915|sp|Q9NY43|BARH2_HUMAN   BarH-like 2 homeobox protein
          Length = 387

 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 30/65 (46%), Positives = 43/65 (66%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           +P   RT F+  QL +LE+ F   KYL+   R+++AA+L L +TQVK W+QNRR K K++
Sbjct: 231 KPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290

Query: 235 EKEGL 239
              GL
Sbjct: 291 TAVGL 295



>gi|23831508|sp|O43711|TLX3_HUMAN   T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
          Length = 291

 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 34/79 (43%), Positives = 44/79 (55%), Gaps = 12/79 (15%)

Query: 159 RNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNET 218
           R PPK  K             RT+F+  Q+ ELEK FH  KYL  A R  +A SL++ + 
Sbjct: 161 RTPPKRKKP------------RTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDA 208

Query: 219 QVKIWFQNRRMKQKKREKE 237
           QVK WFQNRR K +++  E
Sbjct: 209 QVKTWFQNRRTKWRRQTAE 227



>gi|12644330|sp|P56179|DLX6_HUMAN   Homeobox protein DLX-6
          Length = 175

 Score = 63.5 bits (153), Expect = 7e-11
 Identities = 50/140 (35%), Positives = 67/140 (47%), Gaps = 17/140 (12%)

Query: 131 HASHQEACRSPASETSSPAQTF--DWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQL 188
           H+ H    +S    +S+ AQT   D  + K    + G++   G   +    RT +++ QL
Sbjct: 3   HSQHSPYLQS-YHNSSAAAQTRGDDTDQQKTTVIENGEIRFNGKGKKIRKPRTIYSSLQL 61

Query: 189 TELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG---------- 238
             L   F   +YL    R E+AASL L +TQVKIWFQN+R K KK  K+G          
Sbjct: 62  QALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLLKQGSNPHESDPLQ 121

Query: 239 ----LLPISPATPPGNDEKA 254
               L P SPA PP  D  A
Sbjct: 122 GSAALSPRSPALPPVWDVSA 141



>gi|27923815|sp|Q8TAU0|NKX23_HUMAN   Homeobox protein Nkx-2.3 (Homeobox protein NKX-2.3) (Homeobox
           protein NK-2 homolog C)
          Length = 364

 Score = 62.8 bits (151), Expect = 1e-10
 Identities = 40/128 (31%), Positives = 63/128 (49%), Gaps = 9/128 (7%)

Query: 130 LHASHQEACRSPASETSSPAQTFDWMK----VKRNPPKTG--KVGEYGYLGQPNA---VR 180
           +H   +++C  P      P    D  +    +K++    G  K  E     +P +    R
Sbjct: 93  VHTVLRDSCSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPR 152

Query: 181 TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLL 240
             F+  Q+ ELE+ F   +YL+   R  +A+SL+L  TQVKIWFQNRR K K++ ++  L
Sbjct: 153 VLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSL 212

Query: 241 PISPATPP 248
            +    PP
Sbjct: 213 ELGAHAPP 220



>gi|27923733|sp|Q96QS3|ARX_HUMAN   Homeobox protein ARX (Aristaless-related homeobox)
          Length = 562

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 34/71 (47%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT FT+ QL ELE+ F    Y     R E+A  L L E +V++WFQNRR K +KREK G 
Sbjct: 332 RTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGA 391

Query: 240 LPISPATP-PG 249
               P  P PG
Sbjct: 392 QTHPPGLPFPG 402



>gi|17377578|sp|Q99801|NKX31_HUMAN   Homeobox protein Nkx-3.1
          Length = 234

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 28/56 (50%), Positives = 39/56 (69%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKRE 235
           R  F+  Q+ ELE++F   KYL+   R  +A +L+L ETQVKIWFQNRR K K+++
Sbjct: 128 RAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQ 183



>gi|20141538|sp|P31275|HXC12_HUMAN   Homeobox protein Hox-C12 (Hox-3F)
          Length = 282

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 29/54 (53%), Positives = 40/54 (74%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R  ++  QL ELE EF  N+++TR RR E++  L L++ QVKIWFQNRRMK+K+
Sbjct: 218 RKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271



>gi|2828197|sp|P31271|HXA13_HUMAN   Homeobox protein Hox-A13 (Hox-1J)
          Length = 388

 Score = 61.2 bits (147), Expect = 4e-10
 Identities = 28/54 (51%), Positives = 40/54 (74%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R  +T  QL ELE+E+  NK++T+ +R  I+A+  L+E QV IWFQNRR+K+KK
Sbjct: 326 RVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKK 379



>gi|20141539|sp|P31276|HXC13_HUMAN   Homeobox protein Hox-C13 (Hox-3G)
          Length = 330

 Score = 60.8 bits (146), Expect = 5e-10
 Identities = 28/54 (51%), Positives = 40/54 (74%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R  +T  QL ELEKE+  +K++T+ +R  I+A+  L+E QV IWFQNRR+K+KK
Sbjct: 264 RVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317



>gi|38605720|sp|P56177|DLX1_HUMAN   Homeobox protein DLX-1
          Length = 255

 Score = 60.8 bits (146), Expect = 5e-10
 Identities = 39/99 (39%), Positives = 50/99 (50%), Gaps = 17/99 (17%)

Query: 168 GEYGYLGQPNAVR---TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWF 224
           GE  + G+   +R   T + + QL  L + F   +YL    R E+AASL L +TQVKIWF
Sbjct: 117 GEVRFNGKGKKIRKPRTIYCSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWF 176

Query: 225 QNRRMKQKKREKEG--------------LLPISPATPPG 249
           QN+R K KK  K+G              L   SP  PPG
Sbjct: 177 QNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPG 215



>gi|6174907|sp|Q99697|PITX2_HUMAN   Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription
           factor) (Solurshin) (ALL1 responsive protein ARP1)
          Length = 317

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 28/57 (49%), Positives = 39/57 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT+FT++QL ELE  F  N+Y   + R EIA    L E +V++WF+NRR K +KRE+
Sbjct: 89  RTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145



>gi|6093723|sp|O75364|PITX3_HUMAN   Pituitary homeobox 3 (Homeobox protein PITX3)
          Length = 302

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 28/57 (49%), Positives = 39/57 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT+FT++QL ELE  F  N+Y   + R EIA    L E +V++WF+NRR K +KRE+
Sbjct: 66  RTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 122



>gi|3024482|sp|P78337|PITX1_HUMAN   Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot)
          Length = 314

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 29/63 (46%), Positives = 41/63 (65%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT+FT++QL ELE  F  N+Y   + R EIA    L E +V++WF+NRR K +KRE+   
Sbjct: 93  RTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQ 152

Query: 240 LPI 242
           L +
Sbjct: 153 LDL 155



>gi|3915680|sp|Q92988|DLX4_HUMAN   Homeobox protein DLX-4 (DLX-7) (DLX-8)
          Length = 347

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 34/80 (42%), Positives = 45/80 (56%), Gaps = 11/80 (13%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK--- 236
           RT +++ QL  L + F   +YL    R ++AA L L +TQVKIWFQN+R K KK  K   
Sbjct: 229 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS 288

Query: 237 ---EGLLP-----ISPATPP 248
              EG  P     +SP +PP
Sbjct: 289 GGQEGDFPGRTFSVSPCSPP 308



>gi|6016205|sp|O95096|NKX22_HUMAN   Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
          Length = 273

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 37/118 (31%), Positives = 58/118 (49%), Gaps = 2/118 (1%)

Query: 131 HASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTE 190
           ++ H  A  +P  ++SS +      +   N  +T   G  G  G+    R  F+  Q  E
Sbjct: 85  YSLHGLAAGAPPQDSSSKSPEPSADESPDNDKETPGGG--GDAGKKRKRRVLFSKAQTYE 142

Query: 191 LEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPP 248
           LE+ F   +YL+   R  +A+ ++L  TQVKIWFQN R K K+   E  + ++P   P
Sbjct: 143 LERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEKGMEVTPLPSP 200



>gi|50403792|sp|Q92826|HXB13_HUMAN   Homeobox protein Hox-B13
          Length = 284

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 26/54 (48%), Positives = 41/54 (75%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R  ++  QL ELE+E+  NK++T+ +R +I+A+  L+E Q+ IWFQNRR+K+KK
Sbjct: 220 RIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273



>gi|1708211|sp|P52952|NK25_HUMAN   Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E)
           (Cardiac-specific homeobox) (Homeobox protein CSX)
          Length = 324

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 29/69 (42%), Positives = 43/69 (62%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           R  F+  Q+ ELE+ F   +YL+   R ++A+ L+L  TQVKIWFQNRR K K++ ++  
Sbjct: 142 RVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQT 201

Query: 240 LPISPATPP 248
           L +    PP
Sbjct: 202 LELVGLPPP 210



>gi|2851475|sp|P35453|HXD13_HUMAN   Homeobox protein Hox-D13 (Hox-4I)
          Length = 335

 Score = 58.5 bits (140), Expect = 2e-09
 Identities = 27/54 (50%), Positives = 37/54 (68%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R  +T  QL ELE E+  NK++ + +R  I+A+  L+E QV IWFQNRR+K KK
Sbjct: 272 RVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325



>gi|20532396|sp|O43763|TLX2_HUMAN   T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1)
           (Neural crest homeobox protein)
          Length = 284

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 12/79 (15%)

Query: 159 RNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNET 218
           R PPK  K             RT+F+  Q+ ELE+ F   KYL  A R  +A +L++ + 
Sbjct: 152 RTPPKRKKP------------RTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDA 199

Query: 219 QVKIWFQNRRMKQKKREKE 237
           QVK WFQNRR K +++  E
Sbjct: 200 QVKTWFQNRRTKWRRQTAE 218



>gi|6093787|sp|O75360|PROP1_HUMAN   Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary specific
           homeodomain factor)
          Length = 226

 Score = 57.4 bits (137), Expect = 5e-09
 Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 7/116 (6%)

Query: 139 RSPASETSSPAQTFDWMKVKRNPPKTGKVGEY----GYLGQPNAVR---TNFTTKQLTEL 191
           R PA+ T +          +R P   G    +    G  G+P++ R   T F+  QL +L
Sbjct: 25  RHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQL 84

Query: 192 EKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 247
           E  F  N+Y     R  +A    L+E ++++WFQNRR KQ+K+E+  L P++  +P
Sbjct: 85  ESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLAHLSP 140



>gi|2833256|sp|Q14774|HLX1_HUMAN   Homeobox protein HLX1 (Homeobox protein HB24)
          Length = 488

 Score = 57.4 bits (137), Expect = 5e-09
 Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 9/83 (10%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK--------- 230
           R  F+  Q   LEK F   KY+T+  R ++AA L L + QVK+WFQNRRMK         
Sbjct: 280 RAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQA 339

Query: 231 QKKREKEGLLPISPATPPGNDEK 253
           QK ++KE     S   P  + E+
Sbjct: 340 QKDKDKEAGEKPSGGAPAADGEQ 362



>gi|1730095|sp|P52954|LBX1_HUMAN   Transcription factor LBX1
          Length = 280

 Score = 57.4 bits (137), Expect = 5e-09
 Identities = 30/58 (51%), Positives = 36/58 (62%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT FT  Q+ ELEK F + KYL+ A R +IA  L L   QV  WFQNRR K K+  +E
Sbjct: 128 RTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRELEE 185



>gi|6016211|sp|P78426|NK61_HUMAN   Homeobox protein Nkx-6.1
          Length = 367

 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 39/117 (33%), Positives = 55/117 (47%), Gaps = 10/117 (8%)

Query: 128 SPLHASHQEACRSPASETSSPAQT-FDWMKVKRNPP----KTGKVGEYGYL-----GQPN 177
           SP  A+     R P      P +T   W  V ++PP    +       G +     G+  
Sbjct: 178 SPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRK 237

Query: 178 AVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
             R  F+ +Q+  LEK F   KYL    R  +A SL + E+QVK+WFQNRR K +K+
Sbjct: 238 HTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK 294



>gi|547658|sp|Q03014|HHEX_HUMAN   Homeobox protein PRH (Hematopoietically expressed homeobox)
           (Homeobox protein HEX)
          Length = 270

 Score = 56.6 bits (135), Expect = 9e-09
 Identities = 27/58 (46%), Positives = 37/58 (63%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           +  F+  Q  ELEK+F   KYL+   R  +A  LQL+E QVK WFQNRR K ++ ++E
Sbjct: 141 QVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQE 198



>gi|27923817|sp|Q9H2Z4|NK24_HUMAN   Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox
           protein NK-2 homolog D)
          Length = 353

 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 32/78 (41%), Positives = 41/78 (52%), Gaps = 9/78 (11%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK--- 236
           R  F+  Q+ ELE+ F   KYL+   R  +A+ + L  TQVKIWFQN R K K++ K   
Sbjct: 193 RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKA 252

Query: 237 ------EGLLPISPATPP 248
                 EG L   P  PP
Sbjct: 253 AQQLQQEGGLGPPPPPPP 270



>gi|13626112|sp|Q9H161|ALX4_HUMAN   Homeobox protein aristaless-like 4
          Length = 411

 Score = 56.2 bits (134), Expect = 1e-08
 Identities = 29/65 (44%), Positives = 38/65 (58%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT FT+ QL ELEK F    Y     R ++A    L E +V++WFQNRR K +K
Sbjct: 212 GKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRK 271

Query: 234 REKEG 238
           RE+ G
Sbjct: 272 RERFG 276



>gi|6831676|sp|O15266|SHOX_HUMAN   Short stature homeobox protein (Short stature homeobox containing
           protein) (Pseudoautosomal homeobox containing osteogenic
           protein)
          Length = 292

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 27/58 (46%), Positives = 38/58 (65%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RTNFT +QL ELE+ F    Y     R E++  L L+E +V++WFQNRR K +K+E +
Sbjct: 121 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQ 178



>gi|1174819|sp|P43699|TITF1_HUMAN   Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1)
           (Homeobox protein Nkx-2.1) (Homeobox protein NK-2
           homolog A)
          Length = 371

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 50/195 (25%), Positives = 70/195 (35%), Gaps = 29/195 (14%)

Query: 68  GGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGG--------AVGSPQYIHHSYGQEHQSLA 119
           GG      A   G  + P         G+ G         A G PQ  H + G       
Sbjct: 32  GGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVG----GYC 87

Query: 120 LATYNN--SLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPN 177
                N   L P   + + +   P    ++P   F  +     P     +   G LG   
Sbjct: 88  NGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLG 147

Query: 178 AVRTN---------------FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKI 222
            V  N               F+  Q+ ELE+ F   KYL+   R  +A+ + L  TQVKI
Sbjct: 148 DVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKI 207

Query: 223 WFQNRRMKQKKREKE 237
           WFQN R K K++ K+
Sbjct: 208 WFQNHRYKMKRQAKD 222



>gi|3023579|sp|Q15699|CRT1_HUMAN   Cartilage homeoprotein 1 (CART-1)
          Length = 326

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 28/59 (47%), Positives = 37/59 (62%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           RT FT+ QL ELEK F    Y     R ++A   +L E +V++WFQNRR K +KRE+ G
Sbjct: 136 RTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRERYG 194



>gi|18202099|sp|O60902|SHOX2_HUMAN   Short stature homeobox protein 2 (Paired-related homeobox protein
           SHOT) (Homeobox protein Og12X)
          Length = 331

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 27/58 (46%), Positives = 38/58 (65%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RTNFT +QL ELE+ F    Y     R E++  L L+E +V++WFQNRR K +K+E +
Sbjct: 144 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQ 201



>gi|13626107|sp|O95076|ALX3_HUMAN   Homeobox protein aristaless-like 3 (Proline-rich transcription
           factor ALX3)
          Length = 343

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 28/59 (47%), Positives = 36/59 (61%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           RT F+T QL ELEK F    Y     R ++A    L E +V++WFQNRR K +KRE+ G
Sbjct: 157 RTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYG 215



>gi|17380297|sp|Q9Y2V3|RX_HUMAN   Retinal homeobox protein Rx (Retina and anterior neural fold
           homeobox protein)
          Length = 346

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 27/57 (47%), Positives = 37/57 (64%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT FTT QL ELE+ F  + Y     R E+A  + L E +V++WFQNRR K +++EK
Sbjct: 140 RTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK 196



>gi|8134644|sp|Q99453|PHX2B_HUMAN   Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B)
           (PHOX2B homeodomain protein) (Neuroblastoma Phox)
           (NBPhox)
          Length = 314

 Score = 55.1 bits (131), Expect = 3e-08
 Identities = 28/76 (36%), Positives = 43/76 (56%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           +RT FT+ QL ELE+ F    Y     R E+A  + L E +V++WFQNRR K +K+E+  
Sbjct: 101 IRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAA 160

Query: 239 LLPISPATPPGNDEKA 254
               + A    + +K+
Sbjct: 161 AAAAAAAKNGSSGKKS 176



>gi|8134640|sp|O14813|PHX2A_HUMAN   Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A)
           (Aristaless homeobox protein homolog) (ARIX1 homeodomain
           protein)
          Length = 284

 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 26/58 (44%), Positives = 37/58 (63%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           +RT FT+ QL ELE+ F    Y     R E+A  + L E +V++WFQNRR K +K+E+
Sbjct: 93  IRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQER 150



>gi|6016208|sp|O15522|NK28_HUMAN   Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H)
          Length = 239

 Score = 53.5 bits (127), Expect = 8e-08
 Identities = 26/59 (44%), Positives = 35/59 (59%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           R  F+  Q  ELE+ F   +YL+   R ++A+ L+L  TQVKIWFQN R K K+    G
Sbjct: 88  RVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPG 146



>gi|51702790|sp|P63015|PAX6_MOUSE   Paired box protein Pax-6 (Oculorhombin)
 gi|6174889|sp|P26367|PAX6_HUMAN   Paired box protein Pax-6 (Oculorhombin) (Aniridia, type II protein)
          Length = 422

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 24/57 (42%), Positives = 35/57 (61%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT+FT +Q+  LEKEF    Y     R  +AA + L E ++++WF NRR K ++ EK
Sbjct: 214 RTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK 270



>gi|17374365|sp|P58304|CHX10_HUMAN   Homeobox protein CHX10 (Ceh-10 homeodomain containing homolog)
          Length = 361

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 27/57 (47%), Positives = 36/57 (63%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT FT+ QL ELEK F+   Y     R  +A   +L E ++++WFQNRR K +KREK
Sbjct: 152 RTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208



>gi|25009572|sp|Q9NZR4|VSX1_HUMAN   Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner
           nuclear layer homeobox protein) (Homeodomain protein
           RINX)
          Length = 365

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 27/57 (47%), Positives = 34/57 (59%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT FT  QL ELEK F    Y     R  +A   +L E ++++WFQNRR K +KREK
Sbjct: 168 RTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224



>gi|37537960|sp|Q8NHV9|PEPP1_HUMAN   Paired-like homeobox protein PEPP-1 (Ovary-, testis- and
           epididymis-expressed gene protein)
          Length = 184

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 16/167 (9%)

Query: 76  AVYSGNLS-SPMVXXXXXXXGYAG-GAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHAS 133
           +VY   +S +P +       G+ G GA G    ++   G  H++  +      +      
Sbjct: 15  SVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHEN-GMNRDGGMIPEGGGG 73

Query: 134 HQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEK 193
           +QE  + P      PAQ                 G      QP   RT FT  Q+ ELE 
Sbjct: 74  NQEPRQQPQPPPEEPAQA-------------AMEGPQPENMQPRTRRTKFTLLQVEELES 120

Query: 194 EFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLL 240
            F   +Y     R E+A +L + E +V++WF+N+R + ++ ++E +L
Sbjct: 121 VFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELML 167



>gi|48428084|sp|Q8N693|ESX1L_HUMAN   Extraembryonic, spermatogenesis, homeobox 1-like protein
          Length = 406

 Score = 51.2 bits (121), Expect = 4e-07
 Identities = 26/57 (45%), Positives = 35/57 (61%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT FT  QL ELE  F  ++Y     R  +AA L L E +V++WFQNRR K K+ ++
Sbjct: 143 RTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQR 199



>gi|3287764|sp|O43186|CRX_HUMAN   Cone-rod homeobox protein
          Length = 299

 Score = 50.8 bits (120), Expect = 5e-07
 Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 9/78 (11%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK---QKKREK 236
           RT FT  QL ELE  F   +Y     R E+A  + L E++V++WF+NRR K   Q++++K
Sbjct: 43  RTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQK 102

Query: 237 EGLLPISPATPPGNDEKA 254
           +         PPG   KA
Sbjct: 103 Q------QQQPPGGQAKA 114



>gi|8247951|sp|P23759|PAX7_HUMAN   Paired box protein Pax-7 (HUP1)
          Length = 520

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 24/55 (43%), Positives = 33/55 (60%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           RT FT +QL ELEK F    Y     R E+A   +L E +V++WF NRR + +K+
Sbjct: 221 RTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275



>gi|12230168|sp|Q9UBX0|HESX1_HUMAN   Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf)
          Length = 185

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 25/58 (43%), Positives = 33/58 (56%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT FT  Q+  LE  F  N Y     R ++A  L L E +++IWFQNRR K K+  +E
Sbjct: 112 RTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRE 169



>gi|1172022|sp|P23760|PAX3_HUMAN   Paired box protein Pax-3 (HUP2)
          Length = 479

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 23/55 (41%), Positives = 33/55 (60%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           RT FT +QL ELE+ F    Y     R E+A   +L E +V++WF NRR + +K+
Sbjct: 223 RTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ 277



>gi|12644475|sp|Q99811|PRRX2_HUMAN   Paired mesoderm homeobox protein 2 (PRX-2) (Paired related homeobox
           protein 2)
          Length = 253

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 23/57 (40%), Positives = 34/57 (59%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT F + QL  LE+ F    Y     R E+A  + L+E +V++WFQNRR K ++ E+
Sbjct: 108 RTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER 164



>gi|3914276|sp|O43316|PAX4_HUMAN   Paired box protein Pax-4
          Length = 350

 Score = 48.5 bits (114), Expect = 2e-06
 Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 3/112 (2%)

Query: 125 NSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFT 184
           +S++ +  + QE    P +   SPA     +    +  +T + G +   G  N  RT F+
Sbjct: 122 SSINRVLRALQEDQGLPCTRLRSPAVLAPAVLTPHSGSETPR-GTHPGTGHRN--RTIFS 178

Query: 185 TKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
             Q   LEKEF   +Y     R ++A +  L E  V++WF NRR K +++EK
Sbjct: 179 PSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEK 230



>gi|417425|sp|P32242|OTX1_HUMAN   Homeobox protein OTX1
          Length = 354

 Score = 47.8 bits (112), Expect = 4e-06
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           RT FT  QL  LE  F   +Y     R E+A  + L E++V++WF+NRR K +++++ G
Sbjct: 42  RTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSG 100



>gi|6174916|sp|P54821|PRRX1_HUMAN   Paired mesoderm homeobox protein 1 (PRX-1) (Paired related homeobox
           protein 1) (Homeobox protein PHOX1)
          Length = 245

 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 22/57 (38%), Positives = 33/57 (57%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT F + QL  LE+ F    Y     R ++A  + L E +V++WFQNRR K ++ E+
Sbjct: 98  RTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNER 154



>gi|7531125|sp|P56915|GSC_HUMAN   Homeobox protein goosecoid
          Length = 252

 Score = 47.0 bits (110), Expect = 7e-06
 Identities = 22/57 (38%), Positives = 35/57 (61%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT FT +QL  LE  F   KY     R ++A  + L E +V++WF+NRR K +++++
Sbjct: 159 RTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKR 215



>gi|37537987|sp|Q9BQY4|PEP2_HUMAN   Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1)
          Length = 288

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 168 GEYGYLGQPNAVRTN---FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWF 224
           G  G L   NA + N   FT  QL ELE+ F   ++ +   R  +A S+ + E  V+IWF
Sbjct: 123 GAVGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWF 182

Query: 225 QNRRMKQKKREK 236
           +NRR K ++ ++
Sbjct: 183 ENRRAKWRRHQR 194



>gi|6685480|sp|O15499|GSCL_HUMAN   Homeobox protein goosecoid-like (GSC-2)
          Length = 205

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 4/75 (5%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG- 238
           RT F+ +QL  LE  F  N+Y   + R  +A  ++L E +V++WF+NRR K + +++   
Sbjct: 130 RTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKRASA 189

Query: 239 ---LLPISPATPPGN 250
              LLP    +P G+
Sbjct: 190 SARLLPGVKKSPKGS 204



>gi|417427|sp|P32243|OTX2_HUMAN   Homeobox protein OTX2
          Length = 289

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 22/58 (37%), Positives = 36/58 (62%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT FT  QL  LE  F   +Y     R E+A  + L E++V++WF+NRR K ++++++
Sbjct: 42  RTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQ 99



>gi|18202510|sp|Q15911|ATBF1_HUMAN   Alpha-fetoprotein enhancer binding protein (AT motif-binding factor)
            (AT-binding transcription factor 1)
          Length = 3703

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 2/100 (2%)

Query: 140  SPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNK 199
            SP + ++ P  + + +K+   PP   +  +  Y G   + RT FT  QL  L+  F  N 
Sbjct: 2207 SPYNFSNPPITSLEELKIDSRPPSP-EPPKQEYWGSKRSSRTRFTDYQLRVLQDFFDANA 2265

Query: 200  YLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR-EKEG 238
            Y       +++  L L    + +WFQN R K +K  E +G
Sbjct: 2266 YPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYENQG 2305



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 38/149 (25%), Positives = 66/149 (44%), Gaps = 13/149 (8%)

Query: 105  QYIHHSYGQEHQSLALATYNNSLSPLHASH------QEACRSPASETSSPAQTFDWMKVK 158
            Q+IH  +      +    ++ S +PL AS        +   S A+  S+P  T + +K K
Sbjct: 2559 QFIHPQFLDRSLDMPFMLFDPS-NPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRK 2617

Query: 159  RNPPKTGKVGEY--GYLGQP----NAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAAS 212
                 +   GE   G  G+       +RT  T +QL  L +++  +   TR     IA  
Sbjct: 2618 LEEKASASPGENDSGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHE 2677

Query: 213  LQLNETQVKIWFQNRRMKQKKREKEGLLP 241
            + L +  V++WFQN R +++K +   + P
Sbjct: 2678 VGLKKRVVQVWFQNTRARERKGQFRAVGP 2706



 Score = 36.2 bits (82), Expect = 0.013
 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 2/69 (2%)

Query: 180  RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
            RT  T  QL  L + F  N   +  +  E+A    L +  +K WF+N   K+++R K+  
Sbjct: 2149 RTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDS- 2207

Query: 240  LPISPATPP 248
             P + + PP
Sbjct: 2208 -PYNFSNPP 2215



 Score = 35.8 bits (81), Expect = 0.017
 Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 143  SETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQ---PNAVRTNFTTKQLTELEKEFHFNK 199
            SETSS A          +P  +G  G+ G  G        RT  T  QL  L+  F+  +
Sbjct: 2915 SETSSLADP-----CSPSPGASGSAGKSGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYR 2969

Query: 200  YLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
              T      +   + L +  V++WFQN R K+KK
Sbjct: 2970 TPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3003



>gi|47117871|sp|P78411|IRX5_HUMAN   Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein
           5) (Homeodomain protein IRXB2) (IRX-2A)
          Length = 482

 Score = 43.5 bits (101), Expect = 8e-05
 Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 12/138 (8%)

Query: 110 SYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGE 169
           S G      A +T   + SP + SH +    PA+  ++   ++        P   G +G 
Sbjct: 40  SSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGY 99

Query: 170 YGYL--------GQPNAVRTNFTTKQLTELE---KEFHFNKYLTRARRVEIAASLQLNET 218
           + Y         G P A R N T      L+    E   N Y T+  ++ +A   ++  T
Sbjct: 100 HPYAAPLGSYPYGDP-AYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLT 158

Query: 219 QVKIWFQNRRMKQKKREK 236
           QV  WF N R + KK  K
Sbjct: 159 QVSTWFANARRRLKKENK 176



>gi|12643415|sp|Q9UBR4|LHX3_HUMAN   LIM/homeobox protein Lhx3
          Length = 397

 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 20/58 (34%), Positives = 35/58 (60%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT  T KQL  L+  ++ +    R  R ++++   L+   V++WFQNRR K+K+ +K+
Sbjct: 161 RTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKD 218



>gi|123402|sp|P09086|PO2F2_HUMAN   POU domain, class 2, transcription factor 2 (Octamer-binding
           transcription factor 2) (Oct-2) (OTF-2)
           (Lymphoid-restricted immunoglobulin octamer binding
           protein NF-A2)
          Length = 479

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 25/86 (29%), Positives = 40/86 (46%)

Query: 160 NPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQ 219
           N   +  +G  G  G+    RT+  T     LEK F  N+  T    + IA  L + +  
Sbjct: 281 NQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEV 340

Query: 220 VKIWFQNRRMKQKKREKEGLLPISPA 245
           +++WF NRR K+K+       P+ P+
Sbjct: 341 IRVWFCNRRQKEKRINPCSAAPMLPS 366



>gi|20138668|sp|Q969G2|LHX4_HUMAN   LIM/homeobox protein Lhx4
          Length = 367

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 34/58 (58%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT  T KQL  L+  +  +    R  R ++++   L+   V++WFQNRR K+K+ +K+
Sbjct: 138 RTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKD 195



>gi|47117872|sp|P78412|IRX6_HUMAN   Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein
           6) (Homeodomain protein IRXB3)
          Length = 445

 Score = 41.2 bits (95), Expect = 4e-04
 Identities = 51/193 (26%), Positives = 76/193 (39%), Gaps = 12/193 (6%)

Query: 67  SGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQS-LALATYNN 125
           SG  P  APA+      S ++       G A G  G+P Y   +  Q +   L  +    
Sbjct: 39  SGSTP--APALCCAPYDSRLLGSARPELGAALGIYGAP-YAAAAAAQSYPGYLPYSPEPP 95

Query: 126 SLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTT 185
           SL        E   +  S TSS AQ   +   +R   +  +   YG +    A R    T
Sbjct: 96  SLYGALNPQYEFKEAAGSFTSSLAQPGAYYPYERTLGQY-QYERYGAVELSGAGRRKNAT 154

Query: 186 KQLTELEK----EFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLP 241
           ++ T   K    E   N Y T+  ++ +A   ++  TQV  WF N R + KK  K   + 
Sbjct: 155 RETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK---MT 211

Query: 242 ISPATPPGNDEKA 254
            +P    G + KA
Sbjct: 212 WAPKNKGGEERKA 224



>gi|47117873|sp|P78414|IRX1_HUMAN   Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein
           1) (Homeodomain protein IRXA1)
          Length = 480

 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 43/186 (23%), Positives = 67/186 (36%), Gaps = 20/186 (10%)

Query: 69  GYPQ----CAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQYIHHSYGQEHQSLALATYN 124
           GYPQ      P  Y G     +          + G  G+ + +    G    +  L  Y 
Sbjct: 7   GYPQYLSAAGPGAYGGERPGVLAAAAAAAAAASSGRPGAAE-LGGGAGAAAVTSVLGMYA 65

Query: 125 NSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNP------------PKTGKVGEYGY 172
            +     A +  A    A++ S  +Q     ++K NP            P     G++ Y
Sbjct: 66  AAGPYAGAPNYSAFLPYAADLSLFSQMGSQYELKDNPGVHPATFAAHTAPAYYPYGQFQY 125

Query: 173 LGQPNAVR--TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK 230
            G P   +  T  +T  L     E   N Y T+  ++ +A   ++  TQV  WF N R +
Sbjct: 126 -GDPGRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 184

Query: 231 QKKREK 236
            KK  K
Sbjct: 185 LKKENK 190



>gi|60416412|sp|P48742|LHX1_HUMAN   LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox
           protein Lim-1)
          Length = 406

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT    KQL  L+  F      TR  R ++A    LN   +++WFQNRR K+++ ++
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ 240



>gi|18202938|sp|Q9H2C1|LHX5_HUMAN   LIM/homeobox protein Lhx5
          Length = 402

 Score = 40.4 bits (93), Expect = 7e-04
 Identities = 20/57 (35%), Positives = 31/57 (54%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           RT    KQL  L+  F      TR  R ++A    LN   +++WFQNRR K+++ ++
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQ 240



>gi|47117874|sp|P78415|IRX3_HUMAN   Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein
           3) (Homeodomain protein IRXB1)
          Length = 501

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 3/85 (3%)

Query: 168 GEYGYLGQPNAVR--TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQ 225
           G+Y + G P+  +  T  +T  L     E   N Y T+  ++ +A   ++  TQV  WF 
Sbjct: 121 GQYQF-GDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFA 179

Query: 226 NRRMKQKKREKEGLLPISPATPPGN 250
           N R + KK  K    P S     GN
Sbjct: 180 NARRRLKKENKMTWAPRSRTDEEGN 204



>gi|27923801|sp|Q8TE12|LMX1A_HUMAN   LIM homeobox transcription factor 1 alpha (LIM/homeobox protein
           LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1)
          Length = 382

 Score = 39.3 bits (90), Expect = 0.001
 Identities = 21/59 (35%), Positives = 30/59 (50%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           +P   RT  TT+Q    +  F  +    R  R  +AA   L+   V++WFQN+R K KK
Sbjct: 194 RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252



>gi|8247930|sp|O60663|LMX1B_HUMAN   LIM homeobox transcription factor 1 beta (LIM/homeobox protein
           LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2)
          Length = 379

 Score = 39.3 bits (90), Expect = 0.001
 Identities = 21/59 (35%), Positives = 30/59 (50%)

Query: 175 QPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           +P   RT  TT+Q    +  F  +    R  R  +AA   L+   V++WFQN+R K KK
Sbjct: 195 RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253



>gi|28201861|sp|Q9UKI9|PO2F3_HUMAN   POU domain, class 2, transcription factor 3 (Octamer-binding
           transcription factor 11) (Oct-11) (Transcription factor
           Skn-1) (PLA-1 protein)
          Length = 436

 Score = 39.3 bits (90), Expect = 0.001
 Identities = 23/71 (32%), Positives = 32/71 (45%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT+  T     LEK F  N   +      IA  L + +  V++WF NRR K+K+
Sbjct: 279 GRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKR 338

Query: 234 REKEGLLPISP 244
                  PI P
Sbjct: 339 INCPVATPIKP 349



>gi|28201884|sp|P78424|PO6F2_HUMAN   POU domain, class 6, transcription factor 2 (Retina-derived
           POU-domain factor-1) (RPF-1)
          Length = 684

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 7/74 (9%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRM-------KQK 232
           RT+FT + L  L   F  N + +     EIA  L  +   V++WF N+R        + K
Sbjct: 604 RTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLK 663

Query: 233 KREKEGLLPISPAT 246
           + E    +P+ P T
Sbjct: 664 QHEPATAVPLEPLT 677



>gi|8134548|sp|Q9UPM6|LHX61_HUMAN   LIM/homeobox protein Lhx6.1 (Lhx6)
          Length = 363

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 20/68 (29%), Positives = 35/68 (51%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT+FT +QL  ++ +F  +         ++A    L+   +++WFQN R + KK   +  
Sbjct: 223 RTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHP 282

Query: 240 LPISPATP 247
           +P S A P
Sbjct: 283 VPPSGAPP 290



>gi|28202257|sp|P14859|PO2F1_HUMAN   POU domain, class 2, transcription factor 1 (Octamer-binding
           transcription factor 1) (Oct-1) (OTF-1) (NF-A1)
          Length = 743

 Score = 37.4 bits (85), Expect = 0.006
 Identities = 19/54 (35%), Positives = 28/54 (51%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           RT+  T     LEK F  N+  T      IA  L + +  +++WF NRR K+K+
Sbjct: 383 RTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR 436



>gi|47117908|sp|Q9BZI1|IRX2_HUMAN   Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein
           2) (Homeodomain protein IRXA2)
          Length = 471

 Score = 37.4 bits (85), Expect = 0.006
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 3/86 (3%)

Query: 170 YGYLGQPNAVRTNFTTKQLTELE---KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQN 226
           Y Y     A R N T      L+    E   N Y T+  ++ +A   ++  TQV  WF N
Sbjct: 108 YPYQLNDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFAN 167

Query: 227 RRMKQKKREKEGLLPISPATPPGNDE 252
            R + KK  K    P + +     DE
Sbjct: 168 ARRRLKKENKMTWAPRNKSEDEDEDE 193



>gi|12644347|sp|P78413|IRX4_HUMAN   Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein
           4) (Homeodomain protein IRXA3)
          Length = 519

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 19/56 (33%), Positives = 27/56 (48%)

Query: 181 TNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 236
           T  TT  L    +E   N Y T+  ++ +A   ++  TQV  WF N R + KK  K
Sbjct: 150 TRETTSTLKAWLQEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 205



>gi|2495306|sp|Q14863|PO6F1_HUMAN   POU domain, class 6, transcription factor 1 (mPOU homeobox protein)
           (Brain-specific homeobox/POU domain protein 5) (Brain-5)
           (Brn-5 protein)
          Length = 301

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 21/63 (33%), Positives = 28/63 (44%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 239
           RT+FT + +  L   F  N   T     EIA  L  +   V++WF NRR   K   K  +
Sbjct: 238 RTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNV 297

Query: 240 LPI 242
             I
Sbjct: 298 FQI 300



>gi|47606423|sp|P61371|ISL1_HUMAN   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606425|sp|P61373|ISL1_MESAU   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606424|sp|P61372|ISL1_MOUSE   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606422|sp|P61374|ISL1_RAT   Insulin gene enhancer protein ISL-1 (Islet-1)
          Length = 349

 Score = 37.0 bits (84), Expect = 0.007
 Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 15/108 (13%)

Query: 127 LSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTK 186
           LSPLH +        A+E  S  Q      V + P KT +V            RT    K
Sbjct: 147 LSPLHPARP---LQMAAEPISARQPALRPHVHKQPEKTTRV------------RTVLNEK 191

Query: 187 QLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           QL  L   +  N       + ++     L+   +++WFQN+R K KKR
Sbjct: 192 QLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKR 239



>gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN   Zinc finger homeobox protein 2
          Length = 1427

 Score = 36.6 bits (83), Expect = 0.010
 Identities = 21/59 (35%), Positives = 27/59 (45%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           RT FT  Q   L+  F  + Y        +A+ L L    V +WFQN R K +K   EG
Sbjct: 454 RTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARKNACEG 512



 Score = 33.9 bits (76), Expect = 0.063
 Identities = 28/91 (30%), Positives = 43/91 (47%), Gaps = 7/91 (7%)

Query: 164 TGKVGEYGYLGQP---NAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQV 220
           TG     G  G+P     +RT    +QL  L + +  +   TR     I+  + L +  V
Sbjct: 697 TGSEAGGGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVV 756

Query: 221 KIWFQNRRMKQKK---REKEGLLPISPATPP 248
           ++WFQN R +++K   R   G +P SPA  P
Sbjct: 757 QVWFQNTRARERKGQFRSTPGGVP-SPAVKP 786



 Score = 32.0 bits (71), Expect = 0.24
 Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 8/116 (6%)

Query: 129 PLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVG-EYGYLGQPNAV-----RTN 182
           P  +   EAC   A + S  + +   +    +P   G  G   G  G P+ +     RT 
Sbjct: 869 PKASPESEACSLSAGDLSDSSASS--LAEPESPGAGGTSGGPGGGTGVPDGMGQRRYRTQ 926

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
            ++ QL  ++  +   +  T      +   + L +  +++WFQN R K+KK + +G
Sbjct: 927 MSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNARAKEKKAKLQG 982



>gi|730281|sp|P40426|PBX3_HUMAN   Pre-B-cell leukemia transcription factor-3 (Homeobox protein PBX3)
          Length = 434

 Score = 36.2 bits (82), Expect = 0.013
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 5/58 (8%)

Query: 180 RTNFTTKQLTELEKEFHF----NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R NF+ KQ TE+  E+ +    N Y +   + E+A    +  +QV  WF N+R++ KK
Sbjct: 239 RRNFS-KQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK 295



>gi|2506534|sp|P20264|PO33_HUMAN   POU domain, class 3, transcription factor 3 (Brain-specific
           homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein)
          Length = 500

 Score = 35.4 bits (80), Expect = 0.022
 Identities = 21/71 (29%), Positives = 32/71 (45%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT+        LE  F      +      +A SLQL +  V++WF NRR K+K+
Sbjct: 404 GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKEVVRVWFCNRRQKEKR 463

Query: 234 REKEGLLPISP 244
               G+   +P
Sbjct: 464 MTPPGIQQQTP 474



>gi|12230612|sp|Q9UIU6|SIX4_HUMAN   Homeobox protein SIX4 (Sine oculis homeobox homolog 4)
          Length = 760

 Score = 35.4 bits (80), Expect = 0.022
 Identities = 20/72 (27%), Positives = 33/72 (45%)

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPI 242
           F  K    L++ +  N+Y + A +  +A    L+ TQV  WF+NRR + +   +      
Sbjct: 209 FKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSE 268

Query: 243 SPATPPGNDEKA 254
           S   P   DE +
Sbjct: 269 SDGNPSTEDESS 280



>gi|20141754|sp|P41778|PBX1_MOUSE   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
 gi|730279|sp|P40424|PBX1_HUMAN   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
           (Homeobox protein PRL)
          Length = 430

 Score = 35.0 bits (79), Expect = 0.028
 Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 5/58 (8%)

Query: 180 RTNFTTKQLTELEKEFHF----NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R NF  KQ TE+  E+ +    N Y +   + E+A    +  +QV  WF N+R++ KK
Sbjct: 237 RRNFN-KQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293



>gi|1352729|sp|P40425|PBX2_HUMAN   Pre-B-cell leukemia transcription factor-2 (Homeobox protein PBX2)
           (G17 protein)
          Length = 430

 Score = 35.0 bits (79), Expect = 0.028
 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 5/58 (8%)

Query: 180 RTNFTTKQLTELEKEFHF----NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R NF+ KQ TE+  E+ +    N Y +   + E+A    +  +QV  WF N+R++ KK
Sbjct: 248 RRNFS-KQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304



>gi|2506535|sp|Q01851|PO4F1_HUMAN   POU domain, class 4, transcription factor 1 (Brain-specific
           homeobox/POU domain protein 3A) (Brn-3A) (Oct-T1)
           (Homeobox/POU domain protein RDC-1)
          Length = 423

 Score = 35.0 bits (79), Expect = 0.028
 Identities = 18/60 (30%), Positives = 28/60 (46%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT+    +   LE  F      +  +   IA  L L +  V++WF N+R KQK+
Sbjct: 357 GEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 416



>gi|1345629|sp|P49335|PO3F4_HUMAN   POU domain, class 3, transcription factor 4 (Brain-specific
           homeobox/POU domain protein 4) (Brain-4) (Brn-4)
          Length = 361

 Score = 34.3 bits (77), Expect = 0.048
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 11/44 (25%)

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE 252
           +A SLQL +  V++WF NRR K+K+            TPPG+ +
Sbjct: 311 LADSLQLEKEVVRVWFCNRRQKEKR-----------MTPPGDQQ 343



>gi|2495302|sp|Q15319|PO43_HUMAN   POU domain, class 4, transcription factor 3 (Brain-specific
           homeobox/POU domain protein 3C) (Brn-3C)
          Length = 338

 Score = 34.3 bits (77), Expect = 0.048
 Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 22/120 (18%)

Query: 116 QSLALATYNN--SLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYL 173
           +SL L+ +NN  +L P+  +  E   +   E +S  + F+  + KR              
Sbjct: 232 ESLTLS-HNNMIALKPVLQAWLEEAEAAYREKNSKPELFNGSERKRK------------- 277

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
                 RT+    +   LE  F      +  +   IA  L L +  V++WF N+R KQK+
Sbjct: 278 ------RTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 331



>gi|12230598|sp|Q9NPC8|SIX2_HUMAN   Homeobox protein SIX2 (Sine oculis homeobox homolog 2)
          Length = 291

 Score = 34.3 bits (77), Expect = 0.048
 Identities = 17/53 (32%), Positives = 27/53 (50%)

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKRE 235
           F  K  + L + +  N Y +   + E+A +  L  TQV  WF+NRR + +  E
Sbjct: 131 FKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAE 183



>gi|37999770|sp|Q9BYU1|PBX4_HUMAN   Pre-B-cell leukemia transcription factor-4 (Homeobox protein PBX4)
          Length = 330

 Score = 34.3 bits (77), Expect = 0.048
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 5/58 (8%)

Query: 180 RTNFTTKQLTELEKEFHF----NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           R NF+ KQ TE+  E+ +    N Y +   + E+A    L  +QV  WF N+R++ KK
Sbjct: 170 RRNFS-KQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 226



>gi|28202258|sp|P20265|PO3F2_HUMAN   POU domain, class 3, transcription factor 2 (Nervous-system
           specific octamer-binding transcription factor N-Oct-3)
           (Brain-specific homeobox/POU domain protein 2) (Brain-2)
           (Brn-2 protein)
          Length = 443

 Score = 33.9 bits (76), Expect = 0.063
 Identities = 20/65 (30%), Positives = 29/65 (44%)

Query: 174 GQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           G+    RT+        LE  F      +      +A SLQL +  V++WF NRR K+K+
Sbjct: 352 GRKRKKRTSIEVSVKGALESHFLKCPKPSAQEITSLADSLQLEKEVVRVWFCNRRQKEKR 411

Query: 234 REKEG 238
               G
Sbjct: 412 MTPPG 416



>gi|2495300|sp|Q12837|PO42_HUMAN   POU domain, class 4, transcription factor 2 (Brain-specific
           homeobox/POU domain protein 3B) (Brn-3B)
          Length = 410

 Score = 33.9 bits (76), Expect = 0.063
 Identities = 17/54 (31%), Positives = 26/54 (48%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           RT+    +   LE  F      +  +   IA  L L +  V++WF N+R KQK+
Sbjct: 350 RTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKR 403



>gi|2495290|sp|Q15475|SIX1_HUMAN   Homeobox protein SIX1 (Sine oculis homeobox homolog 1)
          Length = 284

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 17/53 (32%), Positives = 26/53 (49%)

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKRE 235
           F  K    L + +  N Y +   + E+A +  L  TQV  WF+NRR + +  E
Sbjct: 131 FKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAE 183



>gi|20978495|sp|Q96A47|ISL2_HUMAN   Insulin gene enhancer protein ISL-2 (Islet-2)
          Length = 359

 Score = 33.1 bits (74), Expect = 0.11
 Identities = 17/56 (30%), Positives = 27/56 (48%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKR 234
           VRT    KQL  L   +  N       + ++     L+   +++WFQN+R K KK+
Sbjct: 194 VRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKK 249



>gi|1709437|sp|Q03052|PO3F1_HUMAN   POU domain, class 3, transcription factor 1 (Octamer-binding
           transcription factor 6) (Oct-6) (POU-domain
           transcription factor SCIP)
          Length = 448

 Score = 32.7 bits (73), Expect = 0.14
 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 5/44 (11%)

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE 252
           +A SLQL +  V++WF NRR K+K+     + P + A  P  D+
Sbjct: 369 LADSLQLEKEVVRVWFCNRRQKEKR-----MTPAAGAGHPPMDD 407



>gi|44889075|sp|Q9H4I2|ZHX3_HUMAN   Zinc fingers and homeoboxes protein 3 (Triple homeobox 1 protein)
          Length = 956

 Score = 31.6 bits (70), Expect = 0.31
 Identities = 15/41 (36%), Positives = 22/41 (53%)

Query: 191 LEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQ 231
           L+  FH   Y T+A    +    +  E Q+KIWF  +R+KQ
Sbjct: 319 LKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQ 359



>gi|12643346|sp|Q9NQ69|LHX9_HUMAN   LIM/homeobox protein Lhx9
          Length = 388

 Score = 31.2 bits (69), Expect = 0.41
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 17/88 (19%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK---RE 235
           +RT+F   QL  ++  F  N         ++A    L +  +++WFQN R K ++   R+
Sbjct: 261 MRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQ 320

Query: 236 KEG--------LLPISPA------TPPG 249
           + G         LP  P+      TPPG
Sbjct: 321 ENGGVDKADGTSLPAPPSADSGALTPPG 348



>gi|123408|sp|P28069|PIT1_HUMAN   Pituitary-specific positive transcription factor 1 (Pit-1) (Growth
           hormone factor 1) (GHF-1)
          Length = 291

 Score = 30.8 bits (68), Expect = 0.53
 Identities = 15/54 (27%), Positives = 26/54 (48%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           RT  +      LE+ F      +    + +A  L L +  V++WF NRR ++K+
Sbjct: 218 RTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKR 271



>gi|12643330|sp|Q9Y5K3|CTPU_HUMAN   Choline-phosphate cytidylyltransferase B (Phosphorylcholine
           transferase B) (CTP:phosphocholine cytidylyltransferase
           B) (CT B) (CCT B) (CCT-beta)
          Length = 369

 Score = 30.8 bits (68), Expect = 0.53
 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 5/54 (9%)

Query: 113 QEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGK 166
           QE  S  L   +   SP+  S     RSP+    SP+ TF W+ +K +PP + K
Sbjct: 304 QERSSRMLQALSPKQSPV--SSPTRSRSPSR---SPSPTFSWLPLKTSPPSSPK 352



>gi|6094293|sp|O95343|SIX3_HUMAN   Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
          Length = 332

 Score = 30.4 bits (67), Expect = 0.70
 Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 180 RTNFTTKQLTELEKEFHF-NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEG 238
           +T+   ++   L +E++  + Y   +++ E+A +  L  TQV  WF+NRR + +    + 
Sbjct: 209 KTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKN 268

Query: 239 LLPISPATPPG 249
            L      P G
Sbjct: 269 RLQHQAIGPSG 279



>gi|46396941|sp|Q8N196|SIX5_HUMAN   Homeobox protein SIX5 (DM locus-associated homeodomain protein)
          Length = 739

 Score = 30.4 bits (67), Expect = 0.70
 Identities = 15/50 (30%), Positives = 25/50 (50%)

Query: 183 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 232
           F  +    L+  +  N+Y T   +  +A    L+ TQV  WF+NRR + +
Sbjct: 208 FKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDR 257



>gi|8247936|sp|P50458|LHX2_HUMAN   LIM/homeobox protein Lhx2 (Homeobox protein LH-2)
          Length = 406

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 15/55 (27%), Positives = 27/55 (49%)

Query: 179 VRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKK 233
           +RT+F   QL  ++  F  N         ++A    L +  +++WFQN R K ++
Sbjct: 269 MRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR 323



>gi|5921744|sp|Q14839|CHD4_HUMAN   Chromodomain helicase-DNA-binding protein 4 (CHD-4) (Mi-2
           autoantigen 218 kDa protein) (Mi2-beta)
          Length = 1912

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 8/63 (12%)

Query: 101 VGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRN 160
           +GSP     S G E + +  A  NNSL P H  ++E      SET +P      +K K+ 
Sbjct: 5   LGSPSPC--SAGSEEEDMD-ALLNNSLPPPHPENEEDPEEDLSETETPK-----LKKKKK 56

Query: 161 PPK 163
           P K
Sbjct: 57  PKK 59



>gi|23503097|sp|P57071|PRD15_HUMAN   PR-domain zinc finger protein 15 (Zinc finger protein 298)
          Length = 1507

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 15/84 (17%)

Query: 129 PLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYG---------------YL 173
           PL  +     R+PA      AQ F W   +  PP  GK+   G               +L
Sbjct: 164 PLSPASAGLRRNPALPPGPFAQNFSWGNQENLPPALGKIANGGGTGAGKAECGYETESHL 223

Query: 174 GQPNAVRTNFTTKQLTELEKEFHF 197
            +P+ +  N  T + ++ E  + F
Sbjct: 224 LEPHEIPLNVNTHKFSDCEFPYEF 247



>gi|51316484|sp|Q8N5B7|LSS5_HUMAN   LAG1 longevity assurance homolog 5
          Length = 392

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 12/62 (19%)

Query: 172 YLGQPNAVRTNFTTKQLTELEKEF-HFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK 230
           Y  QPNA+           LEK F    KY  + R   ++  L  N  +++ WF++RR +
Sbjct: 84  YQAQPNAI-----------LEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQ 132

Query: 231 QK 232
            K
Sbjct: 133 DK 134



>gi|20141973|sp|Q9UHP3|UBP25_HUMAN   Ubiquitin carboxyl-terminal hydrolase 25 (Ubiquitin thiolesterase
           25) (Ubiquitin-specific processing protease 25)
           (Deubiquitinating enzyme 25) (USP on chromosome 21)
          Length = 1087

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 15/98 (15%)

Query: 115 HQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGY-- 172
           H+ L  A     +  LH           SE S  +    W   +  P  T ++  + +  
Sbjct: 334 HECLEAAMIEGEIESLH-----------SENSGKSGQEHWF-TELPPVLTFELSRFEFNQ 381

Query: 173 -LGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEI 209
            LG+P  +       Q+  L++  H N+ +TR +R EI
Sbjct: 382 ALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEI 419



>gi|12230578|sp|O95475|SIX6_HUMAN   Homeobox protein SIX6 (Sine oculis homeobox homolog 6) (Optic
           homeobox 2) (Homeodomain protein OPTX2)
          Length = 246

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 15/54 (27%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query: 180 RTNFTTKQLTELEKEFHF-NKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQK 232
           +T+   ++   L +E++  + Y   +++ E+A +  L  TQV  WF+NRR + +
Sbjct: 131 KTHCFKERTRNLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDR 184



>gi|14285403|sp|Q9NR82|CIQ5_HUMAN   Potassium voltage-gated channel subfamily KQT member 5
           (Voltage-gated potassium channel subunit Kv7.5)
           (Potassium channel alpha subunit KvLQT5) (KQT-like 5)
          Length = 897

 Score = 28.9 bits (63), Expect = 2.0
 Identities = 27/119 (22%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 105 QYIHHSYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKT 164
           Q +  SY  + +S+++AT+   L  LH       +    E SS  +     +V+   P+ 
Sbjct: 340 QCVWRSYAADEKSVSIATWKPHLKALHTC--SPTKKEQGEASSSQKLSFKERVRMASPRG 397

Query: 165 GKV-GEYGYLGQPNAVRTNFTTK-QLTELEKEFHFNKYLTRARRVEIAASLQLNETQVK 221
             +      +G   +  T+ T +   T+++K + FN       R     SL+L  +Q K
Sbjct: 398 QSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFND------RTRFRPSLRLKSSQPK 450



>gi|44888551|sp|Q9UKY1|ZHX1_HUMAN   Zinc fingers and homeoboxes protein 1
          Length = 873

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 26/110 (23%), Positives = 46/110 (41%), Gaps = 6/110 (5%)

Query: 122 TYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRT 181
           T  + ++ +H S      +PA+     AQ    +  ++N     KV     L   N++ T
Sbjct: 234 TSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKV-----LIPVNSIPT 288

Query: 182 -NFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMK 230
            N        L   ++   Y T +    ++A  +  E Q+KIWF  +R+K
Sbjct: 289 YNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLK 338



>gi|400659|sp|Q01860|PO5F1_HUMAN   POU domain, class 5, transcription factor 1 (Octamer-binding
           transcription factor 3) (Oct-3) (Oct-4)
          Length = 360

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 18/58 (31%), Positives = 26/58 (44%)

Query: 180 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 237
           RT+   +    LE  F      T  +   IA  L L +  V++WF NRR K K+   +
Sbjct: 234 RTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSD 291



>gi|52000732|sp|Q99700|ATX2_HUMAN   Ataxin-2 (Spinocerebellar ataxia type 2 protein)
          Length = 1312

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 98   GGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA--SHQEACRSPASETSSPAQTF 152
            GG+  +P  + H   Q  Q+L LA+     +  HA  +      +PAS T SP  +F
Sbjct: 1161 GGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSF 1217



>gi|28201897|sp|Q8N7G0|SPRM1_HUMAN   Sperm 1 POU-domain transcription factor (SPRM-1)
          Length = 328

 Score = 28.5 bits (62), Expect = 2.6
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 191 LEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 247
           LEK F      T  +   IA  LQL +  V++WF N       R K G  P + A+P
Sbjct: 225 LEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYN-------RSKMGSRPTNDASP 274



>gi|34098663|sp|Q92613|PHFG_HUMAN   PHD finger protein 16
          Length = 823

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 155 MKVKRNPPKTGKVGEYGY-----LGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEI 209
           +K  +N  K G+  EY +       Q  + +T+   ++L ELE+EF+     +  R  ++
Sbjct: 363 LKHSQNRQKLGEA-EYPHHRAKEQSQAKSEKTSLRAQKLRELEEEFY-----SLVRVEDV 416

Query: 210 AASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEK 253
           AA L +    V   +   ++K+K    +      P  PP  DE+
Sbjct: 417 AAELGMPTLAVDFIYNYWKLKRKSNFNK------PLFPPKEDEE 454



>gi|28201858|sp|Q06416|PO5L_HUMAN   POU domain, class 5, transcription factor 1-like protein 1 (Octamer
           binding protein 3-like)
          Length = 359

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKREKE 237
           IA  L L +  V++WF NRR K K+   +
Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSD 290



>gi|28201859|sp|Q9BZV7|PO5M_HUMAN   POU domain, class 5, transcription factor 1-like protein 2
          Length = 359

 Score = 28.1 bits (61), Expect = 3.5
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 209 IAASLQLNETQVKIWFQNRRMKQKKREKE 237
           IA  L L +  V++WF NRR K K+   +
Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSD 290



>gi|1350911|sp|P28702|RXRB_HUMAN   Retinoic acid receptor RXR-beta (Retinoid X receptor beta)
          Length = 533

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 3/50 (6%)

Query: 56  SPYALNQEADVSGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGAVGSPQ 105
           SP+ +   +  S G P  AP  +SG +SSP +          GG  G P+
Sbjct: 131 SPFPVISSSMGSPGLPPPAPPGFSGPVSSPQI---NSTVSLPGGGSGPPE 177



>gi|17380567|sp|Q12816|TROP_HUMAN   Trophinin (MAGE-D3 antigen)
          Length = 1387

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 13/42 (30%), Positives = 20/42 (47%)

Query: 59  ALNQEADVSGGYPQCAPAVYSGNLSSPMVXXXXXXXGYAGGA 100
           + + EA +S G   C  A +SG +SS           ++GGA
Sbjct: 760 SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGA 801



>gi|37999907|sp|Q9P275|UBP36_HUMAN   Ubiquitin carboxyl-terminal hydrolase 36 (Ubiquitin thiolesterase 36)
            (Ubiquitin-specific processing protease 36)
            (Deubiquitinating enzyme 36)
          Length = 1121

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 18   CSARAYPSDHRITTFQSCAVSANS-CGGDDRFLNFSAPYSPYALNQEADV 66
            C   A P D  +    SCA SAN  C GD   L+ + P S +   +E+DV
Sbjct: 975  CPRSAKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVS-WNGERESDV 1023



>gi|30173334|sp|Q8TCX5|RHN1_HUMAN   Rhophilin 1
          Length = 695

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 12/36 (33%), Positives = 19/36 (52%), Gaps = 1/36 (2%)

Query: 130 LHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTG 165
           L +  +  C++PAS  +SP    +W + K    KTG
Sbjct: 638 LRSQREHGCKTPASTWASPRPLLNWSR-KAQQGKTG 672



>gi|17366458|sp|Q14573|ITPR3_HUMAN   Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol
           1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)
           (IP3 receptor isoform 3) (InsP3R3)
          Length = 2671

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 13/76 (17%)

Query: 116 QSLALATYNNSLSPLHASHQEACRSPASETS-----SPAQTFDWMKVKRNP--------P 162
           QS   AT +N+L  +   H + CR  A   +         T +++  + NP        P
Sbjct: 271 QSATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDP 330

Query: 163 KTGKVGEYGYLGQPNA 178
           K   +G  G  G+ NA
Sbjct: 331 KAAGMGAQGRTGRRNA 346






  Database: Non-redundant SwissProt sequences
    Posted date:  Mar 15, 2005 10:11 AM
  Number of letters in database: 60,490,055
  Number of sequences in database:  164,271
  
Lambda     K      H
   0.313    0.128    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 678,990
Number of Sequences: 164271
Number of extensions: 31294
Number of successful extensions: 98
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 69
Number of HSP's gapped (non-prelim): 29
length of query: 282
length of database: 6,424,444
effective HSP length: 94
effective length of query: 188
effective length of database: 5,305,374
effective search space: 997410312
effective search space used: 997410312
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 58 (26.9 bits)