>gi|11182425|sp|P56524|HDAC4_HUMAN Histone deacetylase 4 (HD4) Length = 1084 Score = 32.7 bits (73), Expect = 0.20 Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 29/171 (16%) Query: 139 VKLAFREEQKGSDENEEPMMSPDERRKKTRCLRRPKVFATLSC---PLTSKWSPSRQSAF 195 +KL R +QK ++ P++ + T +RP +C P + SP+ S Sbjct: 250 LKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGPSSPNNSSG- 308 Query: 196 WEWEMMGKEERIVRSPDPGLEKFCAPLGLCGPFASTDLSLPRLPLHSDPAFPSVNQNITN 255 + E I P + A L + + S LPL++ P+ P++ + Sbjct: 309 ----SVSAENGIA----PAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGL-- 358 Query: 256 CLRIRPTSSPKPGCDRRKPKPELT----------FPRTRRAPWTRRNPAEK 296 P + P G ++ LT FP T P+ +P E+ Sbjct: 359 -----PATGPSAGTAGQQDTERLTLPALQQRLSLFPGTHLTPYLSTSPLER 404
>gi|47117817|sp|O75376|NCOR1_HUMAN Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) Length = 2440 Score = 30.4 bits (67), Expect = 0.99 Identities = 50/208 (24%), Positives = 77/208 (37%), Gaps = 35/208 (16%) Query: 2 PIVDFHLQKLPAAAAAPFLDKSHSSSPGSPKTAELFFTERTPW-------FHQFPQIPVA 54 P + FH PAAAA F + S +PG P +L+ E T Q Q+ + Sbjct: 1570 PAMPFHRALDPAAAAYLF-QRQLSPTPGYPSQYQLYAMENTRQTILNDYITSQQMQVNLR 1628 Query: 55 PDLSSRGTRRKD------FLSTRRILGAAKV-PVVSFYHSRGVLLKASERAS--GGSKAV 105 PD+ +RG ++ + +TR I+ + P + H G +R + G++ Sbjct: 1629 PDV-ARGLSPREQPLGLPYPATRGIIDLTNMPPTILVPHPGGTSTPPMDRITYIPGTQIT 1687 Query: 106 QPGRKVRNIVGKKRHQNHRIERKIIEEMYLPVRVKLAFREE----------QKGSDENEE 155 P R + H H E R K RE + GS++ Sbjct: 1688 FPPRPYNSASMSPGHPTHLAAAASAEREREREREKERERERIAAASSDLYLRPGSEQPGR 1747 Query: 156 P-------MMSPDERRKKTRCLRRPKVF 176 P SP R ++T +RP VF Sbjct: 1748 PGSHGYVRSPSPSVRTQETMLQQRPSVF 1775
>gi|1346190|sp|P48506|GSH1_HUMAN Glutamate--cysteine ligase catalytic subunit (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS heavy chain) Length = 637 Score = 29.6 bits (65), Expect = 1.7 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 118 KRHQNHRIERKIIEEMYLPVRVKLAFREEQKGSDENEEPMMSPDERRKKTR-CLRRPKVF 176 KRH +H I++ +++ VK ++ K DE E ++S D KK R L KV Sbjct: 16 KRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLSGEKVL 75 Query: 177 ATL 179 TL Sbjct: 76 ETL 78
>gi|60416377|sp|Q96JP5|ZFP91_HUMAN Zinc finger protein 91 homolog (Zfp-91) (FKSG11 protein) Length = 570 Score = 29.3 bits (64), Expect = 2.2 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 117 KKRHQNHRIERKIIEEMYLPVRVKLAFREEQKGSDENEEPMMSPDERRKKTRCLRRPK 174 K R ++ +++ + E+ + V V++ +EE+ E+EEP RRK + R PK Sbjct: 245 KPRRKSGKVKEEK-EKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPK 301
>gi|29839632|sp|Q9GZW5|SDP2_HUMAN SCAN domain-containing protein 2 Length = 306 Score = 29.3 bits (64), Expect = 2.2 Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 260 RPTSSPKPGCDRRKPKPELTFPRTRRAPW 288 +P P P R+P+P L PR + PW Sbjct: 254 QPRQRPSPRPTPRRPRPRLARPRAGQKPW 282
>gi|25089623|sp|Q9P0M2|AK7G_HUMAN A-kinase anchor protein 7 isoform gamma (Protein kinase A anchoring protein 7 isoform gamma) (A-kinase anchoring protein 18) Length = 326 Score = 29.3 bits (64), Expect = 2.2 Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 270 DRRKPKPELTFPRTRRAPWTRRNPAEK 296 + R KP LTF + ++PW R+N +K Sbjct: 190 ESRSFKPHLTFMKLSKSPWLRKNGVKK 216
>gi|60390855|sp|Q8TF74|WIRE_HUMAN WIP-related protein (WIP- and CR16-homologous protein) (PP10631) Length = 440 Score = 29.3 bits (64), Expect = 2.2 Identities = 20/74 (27%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Query: 230 STDLSLPRLPLHSDPAFPSVNQ-NITNCLRIRPTSS----PKPGCDRRKPKPELTFPRTR 284 S+ SLP LP P+ P +++ N T+ ++ +SS P PG P L ++ Sbjct: 140 SSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSK 199 Query: 285 RAPWTRRNPAEKAP 298 + R P P Sbjct: 200 APAYNREKPLPPTP 213
>gi|47606791|sp|Q96GP6|SRC2_HUMAN Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1) Length = 866 Score = 29.3 bits (64), Expect = 2.2 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 10/62 (16%) Query: 220 APLGLCGPFASTDLSLPRLPLHSDPAFPSV------NQNITNCLRIRPTS---SPKPGCD 270 AP LCG F+ + LPR+PL P V N NC + P S P P Sbjct: 484 APHRLCGRFSRISMKLPRIPLRRQ-KLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWS 542 Query: 271 RR 272 R Sbjct: 543 SR 544
>gi|730328|sp|Q06889|EGR3_HUMAN Early growth response protein 3 (EGR-3) (Zinc finger protein pilot) Length = 387 Score = 28.9 bits (63), Expect = 2.9 Identities = 32/91 (35%), Positives = 38/91 (41%), Gaps = 7/91 (7%) Query: 234 SLPRLPLHSDPAFPSV--NQNITNCLRIRPTSSPKPGCDRR-KPKPELTFP---RTRRAP 287 SLP+ PL P P N+ L RP + P GCDRR ELT T P Sbjct: 245 SLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKP 304 Query: 288 WTRRNPAEKAPRSDLRTLCIQRTVVSEKAYS 318 + R RSD T I RT EK ++ Sbjct: 305 FQCRICMRSFSRSDHLTTHI-RTHTGEKPFA 334
>gi|8928360|sp|Q9Z0H3|SNF5_MOUSE SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily B member 1 (Integrase interactor 1 protein) (mSNF5) gi|51338799|sp|Q12824|SNF5_HUMAN SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily B member 1 (Integrase interactor 1 protein) (hSNF5) (BAF47) Length = 385 Score = 28.9 bits (63), Expect = 2.9 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%) Query: 196 WEWEMMGKEERIVRSPDPGLEKFCAPLGLCGPFAST 231 +EW+M KE SP+ K C+ LGL G F +T Sbjct: 279 FEWDMSEKEN----SPEKFALKLCSELGLGGEFVTT 310
>gi|13124503|sp|O60315|SIP1_HUMAN Zinc finger homeobox protein 1b (Smad interacting protein 1) (SMADIP1) (HRIHFB2411) Length = 1214 Score = 28.9 bits (63), Expect = 2.9 Identities = 18/65 (27%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 197 EWEMMGKEERIVRSPDPGLEKFCAPLGLCGPFASTDLSLPRLPLH-----SDPAFPSVNQ 251 EW K + S P LE+ PL + D LPR P+ + P+ ++ Sbjct: 690 EWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHN 749 Query: 252 NITNC 256 ++TNC Sbjct: 750 SVTNC 754
>gi|20140764|sp|Q9C0J8|WD33_HUMAN WD-repeat protein 33 (WD-repeat protein WDC146) Length = 1336 Score = 28.9 bits (63), Expect = 2.9 Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 129 IIEEMYLPVRVKLAFREEQKGSDENEEPMMS 159 +I M +P ++KLA +EQ G DE+ E M+ Sbjct: 440 VIPGMGIPEQLKLAMEQEQMGKDESNEIEMT 470
>gi|30316390|sp|Q9NTI2|AT8A2_HUMAN Potential phospholipid-transporting ATPase IB (ATPase class I type 8A member 2) (ML-1) Length = 1148 Score = 28.5 bits (62), Expect = 3.7 Identities = 42/168 (25%), Positives = 70/168 (41%), Gaps = 30/168 (17%) Query: 23 SHSSSPGSPKTAELFF-TERTPWFHQFPQIPVAPDLSSRGTRRKDFLSTRRILGAAKVPV 81 SH + GS T +FF T W P IP+APD+ RG S LG VP Sbjct: 987 SHLAVWGSMLTWLVFFGIYSTIW----PTIPIAPDM--RGQATMVLSSAHFWLGLFLVPT 1040 Query: 82 VSF----------YHSRGVLLKASERASGGSKAVQPGRKV-RNIVGKKRHQNHRIERKII 130 + + LL+ + S+ + G+ V R+ GK+ ++ R+ +++ Sbjct: 1041 ACLIEDVAWRAAKHTCKKTLLEEVQELETKSRVL--GKAVLRDSNGKRLNERDRLIKRLG 1098 Query: 131 EE----------MYLPVRVKLAFREEQKGSDENEEPMMSPDERRKKTR 168 + + V AF +E+ G+ EE + + D +KK+R Sbjct: 1099 RKTPPTLFRGSSLQQGVPHGYAFSQEEHGAVSQEEVIRAYDTTKKKSR 1146
>gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2] Length = 2805 Score = 28.5 bits (62), Expect = 3.7 Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 14/123 (11%) Query: 144 REEQKGSDENEEPMMSPDERRKKTRCLRRPKVFATLSCPLTSKWSPSRQSAFWEWEMMGK 203 RE G+ + P +S K+ R LS P++ K S F + G Sbjct: 1986 REPPLGAAGDWPPCLST----KEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGP 2041 Query: 204 EERIVRSPDPGLEKFCAPLGLCGPFASTDLSLPRLPLHSDPAFPSVNQNITNCLRIRPTS 263 P P +E P + PR P+ S P +N NI +C R + Sbjct: 2042 TVPPRXEPGPSMEPSLTPPAVP----------PRAPILSKGPSPPLNGNILSCSPDRRSP 2091 Query: 264 SPK 266 SPK Sbjct: 2092 SPK 2094
>gi|13124645|sp|O75038|Y450_HUMAN Hypothetical protein KIAA0450 Length = 425 Score = 28.1 bits (61), Expect = 4.9 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 244 PAFPSVNQNITNCLRIRPTSSPKPGCDRRKPKPEL 278 PA PSV+Q I PT S KPG R+ PEL Sbjct: 130 PARPSVSQRILRRTASAPTKSQKPG---RRGFPEL 161
>gi|3929376|sp|Q12872|SFRS8_HUMAN Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog) Length = 951 Score = 27.7 bits (60), Expect = 6.4 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 17/115 (14%) Query: 85 YHSRGVLLKASERASGGSKAVQPG-----RKVRNIVGKKRHQNHRIERKIIEEMYLPVRV 139 YHS K+ R+ +K P R+ R+ R + H ER+ EE +P Sbjct: 774 YHSSS---KSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRRRAHSPERRR-EERSVPTAY 829 Query: 140 KLAFREEQKGSDENEEPMMSPDERRKKTRCLRRPKVFATLSCPLTSKWSPSRQSA 194 +++ G+ SP E++KK R R K S + SPS+Q+A Sbjct: 830 RVS---RSPGASRKRTRSRSPHEKKKKRRSRSRTK-----SKARSQSVSPSKQAA 876
>gi|2498017|sp|Q16665|HIF1A_HUMAN Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT interacting protein) (Member of PAS protein 1) (MOP1) Length = 826 Score = 27.7 bits (60), Expect = 6.4 Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 3/43 (6%) Query: 232 DLSLPRLPLHSDPAFPSVNQNITNCLRIRPTSSPKPGCDRRKP 274 D L +PL++D PS N+ + N I SP P + KP Sbjct: 422 DQQLEEVPLYNDVMLPSPNEKLQN---INLAMSPLPTAETPKP 461
>gi|52000873|sp|Q70EK9|UBP51_HUMAN Ubiquitin carboxyl-terminal hydrolase 51 (Ubiquitin thiolesterase 51) (Ubiquitin-specific processing protease 51) (Deubiquitinating enzyme 51) Length = 711 Score = 27.7 bits (60), Expect = 6.4 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 5/49 (10%) Query: 250 NQNITNCLRIRPTSSPKPGCDRRKPKPELTFPRTRRAPWTRRNPAEKAP 298 ++ + + +R SS P C RRKP+P PR R +R P AP Sbjct: 80 DEKVLPSIPLRCHSSSSPVCPRRKPRPR-PQPRAR----SRSQPGLSAP 123
>gi|57012964|sp|Q92922|SMRC1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) Length = 1105 Score = 27.7 bits (60), Expect = 6.4 Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 138 RVKLAFREEQKGSDENEEPMMSPDERRKKTRCLRRPKVFATLSCPLTSKWSPSRQSAFWE 197 R ++FR Q+ S +NEEP+ SP+ R +K R + + P T S + + Sbjct: 291 RKPVSFR--QRISTKNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQ 348 Query: 198 WEMMGK 203 + GK Sbjct: 349 ASLYGK 354
>gi|38258418|sp|Q15637|SF01_HUMAN Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point binding protein mBBP) (BBP) Length = 639 Score = 27.3 bits (59), Expect = 8.4 Identities = 12/37 (32%), Positives = 16/37 (43%), Gaps = 1/37 (2%) Query: 263 SSPKPGCDRRKPKPELTFPRTR-RAPWTRRNPAEKAP 298 S+P+P P P T+ R PW P+E P Sbjct: 342 SAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRP 378
>gi|21542178|sp|Q96BK5|PII1_HUMAN Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver-related putative tumor suppressor) (67-11-3 protein) Length = 328 Score = 27.3 bits (59), Expect = 8.4 Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 9 QKLPAAAAAPFLDKSHSSSPGSPKTAELFFTERTPWFHQFPQIPV-APDLSSRGTRRK 65 +K P A+P + + ++ S T + +F +R PQ+PV D+S RK Sbjct: 153 KKTPEGDASPSTPEENETTTTSAFTIQEYFAKRMAALKNKPQVPVPGSDISETQVERK 210
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.320 0.135 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 1,109,951 Number of Sequences: 164271 Number of extensions: 56668 Number of successful extensions: 234 Number of sequences better than 10.0: 4 Number of HSP's better than 10.0 without gapping: 2 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 230 Number of HSP's gapped (non-prelim): 6 length of query: 347 length of database: 6,971,665 effective HSP length: 97 effective length of query: 250 effective length of database: 5,655,860 effective search space: 1413965000 effective search space used: 1413965000 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 59 (27.3 bits)