BLASTP 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. RID: 1111159442-15660-192106550163.BLASTQ4 Query= FGENESH: 3 5 exon (s) 106574 - 170728 437 aa, chain + (437 letters) Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters If you have any problems or questions with the results of this search please refer to the BLAST FAQs Taxonomy reports
RID: 1111159442-15660-192106550163.BLASTQ4
Query= FGENESH: 3 5 exon (s) 106574 - 170728 437 aa, chain + (437 letters)
Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters
If you have any problems or questions with the results of this search please refer to the BLAST FAQs
Taxonomy reports
Score E Sequences producing significant alignments: (bits) Value gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (T... 184 4e-47 gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain ... 184 7e-47 gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (A... 171 5e-43 gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Trop... 167 7e-42 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 50 2e-06 gi|2500345|sp|P55769|NHPX_HUMAN NHP2-like protein 1 (High m... 49 4e-06 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 47 1e-05 gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Di... 44 8e-05 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 44 1e-04 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 43 2e-04 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 42 3e-04 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 42 3e-04 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 42 4e-04 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 42 4e-04 gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X 42 4e-04 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 42 5e-04 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 42 5e-04 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 42 5e-04 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 41 7e-04 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 41 0.001 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 40 0.001 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 40 0.002 gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 40 0.002 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 40 0.002 gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium ... 40 0.002 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 40 0.002 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 40 0.002 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 40 0.002 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 39 0.003 gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-acti... 39 0.005 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 39 0.005 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 39 0.005 gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of... 39 0.005 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 38 0.006 gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen... 38 0.006 gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein ... 38 0.008 gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat pr... 38 0.008 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 37 0.010 gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornif... 37 0.010 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 37 0.013 gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylat... 37 0.013 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 37 0.013 gi|1706487|sp|P98082|DAB2_HUMAN Disabled homolog 2 (Differe... 37 0.017 gi|34395524|sp|Q92888|ARH1_HUMAN Rho guanine nucleotide exc... 37 0.017 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 37 0.017 gi|12643957|sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepres... 37 0.017 gi|464486|sp|P35247|PSPD_HUMAN Pulmonary surfactant-associa... 36 0.023 gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin... 36 0.023 gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (... 36 0.023 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 36 0.030 gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein ki... 36 0.030 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 36 0.030 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 35 0.039 gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation ini... 35 0.039 gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Pl... 35 0.039 gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly ... 35 0.050 gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond s... 35 0.050 gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 35 0.050 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 35 0.050 gi|1350911|sp|P28702|RXRB_HUMAN Retinoic acid receptor RXR-... 35 0.066 gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 35 0.066 gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein... 35 0.066 gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated pr... 35 0.066 gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor rec... 34 0.086 gi|464541|sp|P35241|RADI_HUMAN Radixin 34 0.086 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 34 0.086 gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kin... 34 0.086 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 34 0.086 gi|52001469|sp|P04280|PRP1_HUMAN Basic salivary proline-ric... 34 0.086 gi|37999491|sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 (... 34 0.086 gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B 34 0.11 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 34 0.11 gi|52001468|sp|P02812|PRB2_HUMAN Basic salivary proline-ric... 34 0.11 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 33 0.15 gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin conden... 33 0.15 gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (C... 33 0.15 gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleo... 33 0.19 gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein... 33 0.19 gi|23396825|sp|Q9BRQ0|PYG2_HUMAN Pygopus homolog 2 33 0.19 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 33 0.19 gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DN... 33 0.19 gi|13626143|sp|O75973|C1RF_HUMAN C1q-related factor precurs... 33 0.19 gi|115313|sp|P20908|CA15_HUMAN Collagen alpha 1(V) chain pr... 33 0.19 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 33 0.25 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 33 0.25 gi|1168617|sp|P46379|BAT3_HUMAN Large proline-rich protein ... 33 0.25 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 33 0.25 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 33 0.25 gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor... 32 0.33 gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate... 32 0.33 gi|1703310|sp|Q01484|ANK2_HUMAN Ankyrin 2 (Brain ankyrin) (... 32 0.33 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 32 0.33 gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like pr... 32 0.43 gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (His... 32 0.43 gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modula... 32 0.43 gi|59800456|sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome ... 32 0.43 gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine rec... 32 0.43 gi|34223720|sp|P25940|CA35_HUMAN Collagen alpha 3(V) chain ... 32 0.43 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 32 0.43 gi|42559826|sp|Q8IWN7|RP1L1_HUMAN Retinitis pigmentosa 1-li... 32 0.43 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 32 0.56 gi|27734440|sp|Q96RN5|PCQAP_HUMAN Positive cofactor 2 gluta... 32 0.56 gi|51338841|sp|Q9Y3L3|3BP1_HUMAN SH3-domain binding protein... 32 0.56 gi|13431960|sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syn... 32 0.56 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 32 0.56 gi|21542396|sp|P12107|CA1B_HUMAN Collagen alpha 1(XI) chain... 32 0.56 gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleo... 31 0.73 gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myos... 31 0.73 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 31 0.73 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 31 0.73 gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein 31 0.73 gi|50400978|sp|Q7Z5J4|RAI1_HUMAN Retinoic acid induced prot... 31 0.73 gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat p... 31 0.73 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 31 0.73 gi|12643900|sp|Q9UMN6|MLL4_HUMAN Myeloid/lymphoid or mixed-... 31 0.95 gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precur... 31 0.95 gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi... 31 0.95 gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding prot... 31 0.95 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 31 0.95 gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled... 31 0.95 gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1... 30 1.2 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 30 1.2 gi|115306|sp|P02461|CA13_HUMAN Collagen alpha 1(III) chain ... 30 1.2 gi|114870|sp|P20749|BCL3_HUMAN B-cell lymphoma 3-encoded pr... 30 1.2 gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor 30 1.2 gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 30 1.2 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 30 1.2 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 30 1.2 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 30 1.2 gi|41688789|sp|Q96J92|WNK4_HUMAN Serine/threonine-protein k... 30 1.2 gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain prot... 30 1.2 gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein ki... 30 1.2 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 30 1.2 gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL... 30 1.6 gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effecto... 30 1.6 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 30 1.6 gi|59803073|sp|O95104|SFR15_HUMAN Splicing factor, arginine... 30 1.6 gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysac... 30 1.6 gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily... 30 1.6 gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 ... 30 1.6 gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain pr... 30 1.6 gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskele... 30 1.6 gi|21542263|sp|Q9C0C2|TABP_HUMAN 182 kDa tankyrase 1-bindin... 30 1.6 gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific pro... 30 2.1 gi|2498882|sp|Q15459|SF3A1_HUMAN Splicing factor 3 subunit ... 30 2.1 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 30 2.1 gi|728997|sp|Q07092|CA1F_HUMAN Collagen alpha 1(XVI) chain ... 30 2.1 gi|23813917|sp|Q13356|PPL2_HUMAN Peptidyl-prolyl cis-trans ... 30 2.1 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 30 2.1 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 30 2.1 gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chai... 30 2.1 gi|1174915|sp|P46939|UTRO_HUMAN Utrophin (Dystrophin-relate... 30 2.1 gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death prot... 30 2.1 gi|33302611|sp|P12036|NFH_HUMAN Neurofilament triplet H pro... 30 2.1 gi|60416429|sp|O43516|WASIP_HUMAN Wiskott-Aldrich syndrome ... 30 2.1 gi|20138588|sp|Q14766|LTBL_HUMAN Latent transforming growth... 30 2.1 gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI 29 2.8 gi|38605641|sp|Q9Y3Q4|HCN4_HUMAN Potassium/sodium hyperpola... 29 2.8 gi|1709337|sp|P55209|NPL1_HUMAN Nucleosome assembly protein... 29 2.8 gi|9296963|sp|Q9Y463|DYR1B_HUMAN Dual-specificity tyrosine-... 29 2.8 gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting p... 29 2.8 gi|133498|sp|P13631|RRG1_HUMAN Retinoic acid receptor gamma... 29 2.8 gi|131005|sp|P10163|PR4S_HUMAN Basic salivary proline-rich ... 29 2.8 gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclero... 29 2.8 gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skel... 29 2.8 gi|41688792|sp|Q9BYP7|WNK3_HUMAN Serine/threonine-protein k... 29 2.8 gi|41688816|sp|Q96T58|MINT_HUMAN Msx2-interacting protein (... 29 2.8 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 29 2.8 gi|45476939|sp|Q8IX07|FOG1_HUMAN Zinc finger protein ZFPM1 ... 29 2.8 gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-... 29 2.8 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 29 3.6 gi|1708973|sp|P51608|MECP2_HUMAN Methyl-CpG-binding protein... 29 3.6 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 29 3.6 gi|21362754|sp|Q12796|PNR1_HUMAN Proline-rich nuclear recep... 29 3.6 gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1... 29 3.6 gi|139820|sp|P18887|XRCC1_HUMAN DNA-repair protein XRCC1 29 3.6 gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (... 29 3.6 gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE fam... 29 3.6 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 29 3.6 gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kD... 29 3.6 gi|131011|sp|P10162|PR4L_HUMAN Basic salivary proline-rich ... 29 3.6 gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 4... 29 3.6 gi|20141192|sp|O60885|BRD4_HUMAN Bromodomain-containing pro... 29 3.6 gi|13123997|sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guan... 29 3.6 gi|18202099|sp|O60902|SHOX2_HUMAN Short stature homeobox pr... 29 3.6 gi|13432104|sp|P13942|CA2B_HUMAN Collagen alpha 2(XI) chain... 29 3.6 gi|52001471|sp|P10161|PR4M_HUMAN Basic salivary proline-ric... 29 3.6 gi|51315800|sp|Q9UPA5|BSN_HUMAN Bassoon protein (Zinc-finge... 29 3.6 gi|29337113|sp|Q96AJ9|VT1A_HUMAN Vesicle transport through ... 28 4.7 gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist... 28 4.7 gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense tra... 28 4.7 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 28 4.7 gi|3122058|sp|Q13201|MRN1_HUMAN Multimerin 1 precursor (End... 28 4.7 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 28 4.7 gi|547700|sp|Q01101|INSM1_HUMAN Zinc finger protein IA-1 (I... 28 4.7 gi|60390213|sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40-containi... 28 4.7 gi|52000732|sp|Q99700|ATX2_HUMAN Ataxin-2 (Spinocerebellar ... 28 4.7 gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense tra... 28 4.7 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 28 4.7 gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like pro... 28 4.7 gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-termin... 28 4.7 gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin ... 28 4.7 gi|29336893|sp|Q96DN6|MBD6_HUMAN Methyl-CpG-binding domain ... 28 4.7 gi|20177873|sp|Q9UQB3|CTD2_HUMAN Catenin delta-2 (Delta-cat... 28 4.7 gi|30580335|sp|O75167|PHR2_HUMAN Phosphatase and actin regu... 28 4.7 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 28 4.7 gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal... 28 4.7 gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain... 28 4.7 gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinas... 28 4.7 gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-... 28 4.7 gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonuc... 28 6.2 gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein ... 28 6.2 gi|1345650|sp|Q02388|CO7A1_HUMAN Collagen alpha 1(VII) chai... 28 6.2 gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal... 28 6.2 gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreduct... 28 6.2 gi|27805394|sp|O60641|AP180_HUMAN Clathrin coat assembly pr... 28 6.2 gi|1711641|sp|P17600|SYN1_HUMAN Synapsin-1 (Synapsin I) (Br... 28 6.2 gi|34098740|sp|Q9NYF0|DAC1_HUMAN Dapper homolog 1 (hDPR1) (... 28 6.2 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 28 6.2 gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa parane... 28 6.2 gi|6016211|sp|P78426|NK61_HUMAN Homeobox protein Nkx-6.1 28 6.2 gi|8928568|sp|Q12888|TP53B_HUMAN Tumor suppressor p53-bindi... 28 6.2 gi|57012964|sp|Q92922|SMRC1_HUMAN SWI/SNF-related matrix-as... 28 6.2 gi|29429203|sp|P54259|DRPLA_HUMAN Atrophin-1 (Dentatorubral... 28 6.2 gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia... 28 6.2 gi|38258268|sp|Q9UPQ9|K1093_HUMAN Protein KIAA1093 28 6.2 gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal... 28 8.1 gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 prot... 28 8.1 gi|135846|sp|P20962|PTMS_HUMAN Parathymosin 28 8.1 gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Vi... 28 8.1 gi|12229810|sp|Q9NYJ7|DLL3_HUMAN Delta-like protein 3 precu... 28 8.1 gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (... 28 8.1 gi|461675|sp|P29400|CA54_HUMAN Collagen alpha 5(IV) chain p... 28 8.1 gi|38372706|sp|Q8NGJ4|O52E2_HUMAN Olfactory receptor 52E2 28 8.1 gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 3... 28 8.1 gi|34098675|sp|Q96D71|REP1_HUMAN RalBP1 associated Eps doma... 28 8.1 gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated prot... 28 8.1 gi|6136124|sp|O75385|ULK1_HUMAN Serine/threonine-protein ki... 28 8.1 gi|29429200|sp|P53814|SMOO_HUMAN Smoothelin 28 8.1 gi|17433253|sp|Q9NZQ3|SP90_HUMAN SH3 adapter protein SPIN90... 28 8.1 gi|6686051|sp|O00294|TULP1_HUMAN Tubby related protein 1 (T... 28 8.1 gi|28380068|sp|Q14686|NCOA6_HUMAN Nuclear receptor coactiva... 28 8.1 gi|21263906|sp|Q99954|PRL5_HUMAN Proline-rich protein 5 pre... 28 8.1 gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment facto... 28 8.1 gi|46397803|sp|O60732|MGC1_HUMAN Melanoma-associated antige... 28 8.1 gi|1730095|sp|P52954|LBX1_HUMAN Transcription factor LBX1 28 8.1 gi|20141212|sp|P20849|CA19_HUMAN Collagen alpha 1(IX) chain... 28 8.1 gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) 28 8.1 Alignments
Score E Sequences producing significant alignments: (bits) Value gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (T... 184 4e-47 gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain ... 184 7e-47 gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (A... 171 5e-43 gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Trop... 167 7e-42 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 50 2e-06 gi|2500345|sp|P55769|NHPX_HUMAN NHP2-like protein 1 (High m... 49 4e-06 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 47 1e-05 gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Di... 44 8e-05 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 44 1e-04 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 43 2e-04 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 42 3e-04 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 42 3e-04 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 42 4e-04 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 42 4e-04 gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X 42 4e-04 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 42 5e-04 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 42 5e-04 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 42 5e-04 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 41 7e-04 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 41 0.001 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 40 0.001 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 40 0.002 gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 40 0.002 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 40 0.002 gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium ... 40 0.002 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 40 0.002 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 40 0.002 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 40 0.002 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 39 0.003 gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-acti... 39 0.005 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 39 0.005 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 39 0.005 gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of... 39 0.005 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 38 0.006 gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen... 38 0.006 gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein ... 38 0.008 gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat pr... 38 0.008 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 37 0.010 gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornif... 37 0.010 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 37 0.013 gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylat... 37 0.013 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 37 0.013 gi|1706487|sp|P98082|DAB2_HUMAN Disabled homolog 2 (Differe... 37 0.017 gi|34395524|sp|Q92888|ARH1_HUMAN Rho guanine nucleotide exc... 37 0.017 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 37 0.017 gi|12643957|sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepres... 37 0.017 gi|464486|sp|P35247|PSPD_HUMAN Pulmonary surfactant-associa... 36 0.023 gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin... 36 0.023 gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (... 36 0.023 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 36 0.030 gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein ki... 36 0.030 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 36 0.030 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 35 0.039 gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation ini... 35 0.039 gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Pl... 35 0.039 gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly ... 35 0.050 gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond s... 35 0.050 gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 35 0.050 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 35 0.050 gi|1350911|sp|P28702|RXRB_HUMAN Retinoic acid receptor RXR-... 35 0.066 gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 35 0.066 gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein... 35 0.066 gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated pr... 35 0.066 gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor rec... 34 0.086 gi|464541|sp|P35241|RADI_HUMAN Radixin 34 0.086 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 34 0.086 gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kin... 34 0.086 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 34 0.086 gi|52001469|sp|P04280|PRP1_HUMAN Basic salivary proline-ric... 34 0.086 gi|37999491|sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 (... 34 0.086 gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B 34 0.11 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 34 0.11 gi|52001468|sp|P02812|PRB2_HUMAN Basic salivary proline-ric... 34 0.11 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 33 0.15 gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin conden... 33 0.15 gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (C... 33 0.15 gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleo... 33 0.19 gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein... 33 0.19 gi|23396825|sp|Q9BRQ0|PYG2_HUMAN Pygopus homolog 2 33 0.19 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 33 0.19 gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DN... 33 0.19 gi|13626143|sp|O75973|C1RF_HUMAN C1q-related factor precurs... 33 0.19 gi|115313|sp|P20908|CA15_HUMAN Collagen alpha 1(V) chain pr... 33 0.19 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 33 0.25 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 33 0.25 gi|1168617|sp|P46379|BAT3_HUMAN Large proline-rich protein ... 33 0.25 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 33 0.25 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 33 0.25 gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor... 32 0.33 gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate... 32 0.33 gi|1703310|sp|Q01484|ANK2_HUMAN Ankyrin 2 (Brain ankyrin) (... 32 0.33 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 32 0.33 gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like pr... 32 0.43 gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (His... 32 0.43 gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modula... 32 0.43 gi|59800456|sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome ... 32 0.43 gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine rec... 32 0.43 gi|34223720|sp|P25940|CA35_HUMAN Collagen alpha 3(V) chain ... 32 0.43 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 32 0.43 gi|42559826|sp|Q8IWN7|RP1L1_HUMAN Retinitis pigmentosa 1-li... 32 0.43 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 32 0.56 gi|27734440|sp|Q96RN5|PCQAP_HUMAN Positive cofactor 2 gluta... 32 0.56 gi|51338841|sp|Q9Y3L3|3BP1_HUMAN SH3-domain binding protein... 32 0.56 gi|13431960|sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syn... 32 0.56 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 32 0.56 gi|21542396|sp|P12107|CA1B_HUMAN Collagen alpha 1(XI) chain... 32 0.56 gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleo... 31 0.73 gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myos... 31 0.73 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 31 0.73 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 31 0.73 gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein 31 0.73 gi|50400978|sp|Q7Z5J4|RAI1_HUMAN Retinoic acid induced prot... 31 0.73 gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat p... 31 0.73 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 31 0.73 gi|12643900|sp|Q9UMN6|MLL4_HUMAN Myeloid/lymphoid or mixed-... 31 0.95 gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precur... 31 0.95 gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi... 31 0.95 gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding prot... 31 0.95 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 31 0.95 gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled... 31 0.95 gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1... 30 1.2 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 30 1.2 gi|115306|sp|P02461|CA13_HUMAN Collagen alpha 1(III) chain ... 30 1.2 gi|114870|sp|P20749|BCL3_HUMAN B-cell lymphoma 3-encoded pr... 30 1.2 gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor 30 1.2 gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 30 1.2 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 30 1.2 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 30 1.2 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 30 1.2 gi|41688789|sp|Q96J92|WNK4_HUMAN Serine/threonine-protein k... 30 1.2 gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain prot... 30 1.2 gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein ki... 30 1.2 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 30 1.2 gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL... 30 1.6 gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effecto... 30 1.6 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 30 1.6 gi|59803073|sp|O95104|SFR15_HUMAN Splicing factor, arginine... 30 1.6 gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysac... 30 1.6 gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily... 30 1.6 gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 ... 30 1.6 gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain pr... 30 1.6 gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskele... 30 1.6 gi|21542263|sp|Q9C0C2|TABP_HUMAN 182 kDa tankyrase 1-bindin... 30 1.6 gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific pro... 30 2.1 gi|2498882|sp|Q15459|SF3A1_HUMAN Splicing factor 3 subunit ... 30 2.1 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 30 2.1 gi|728997|sp|Q07092|CA1F_HUMAN Collagen alpha 1(XVI) chain ... 30 2.1 gi|23813917|sp|Q13356|PPL2_HUMAN Peptidyl-prolyl cis-trans ... 30 2.1 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 30 2.1 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 30 2.1 gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chai... 30 2.1 gi|1174915|sp|P46939|UTRO_HUMAN Utrophin (Dystrophin-relate... 30 2.1 gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death prot... 30 2.1 gi|33302611|sp|P12036|NFH_HUMAN Neurofilament triplet H pro... 30 2.1 gi|60416429|sp|O43516|WASIP_HUMAN Wiskott-Aldrich syndrome ... 30 2.1 gi|20138588|sp|Q14766|LTBL_HUMAN Latent transforming growth... 30 2.1 gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI 29 2.8 gi|38605641|sp|Q9Y3Q4|HCN4_HUMAN Potassium/sodium hyperpola... 29 2.8 gi|1709337|sp|P55209|NPL1_HUMAN Nucleosome assembly protein... 29 2.8 gi|9296963|sp|Q9Y463|DYR1B_HUMAN Dual-specificity tyrosine-... 29 2.8 gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting p... 29 2.8 gi|133498|sp|P13631|RRG1_HUMAN Retinoic acid receptor gamma... 29 2.8 gi|131005|sp|P10163|PR4S_HUMAN Basic salivary proline-rich ... 29 2.8 gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclero... 29 2.8 gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skel... 29 2.8 gi|41688792|sp|Q9BYP7|WNK3_HUMAN Serine/threonine-protein k... 29 2.8 gi|41688816|sp|Q96T58|MINT_HUMAN Msx2-interacting protein (... 29 2.8 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 29 2.8 gi|45476939|sp|Q8IX07|FOG1_HUMAN Zinc finger protein ZFPM1 ... 29 2.8 gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-... 29 2.8 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 29 3.6 gi|1708973|sp|P51608|MECP2_HUMAN Methyl-CpG-binding protein... 29 3.6 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 29 3.6 gi|21362754|sp|Q12796|PNR1_HUMAN Proline-rich nuclear recep... 29 3.6 gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1... 29 3.6 gi|139820|sp|P18887|XRCC1_HUMAN DNA-repair protein XRCC1 29 3.6 gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (... 29 3.6 gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE fam... 29 3.6 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 29 3.6 gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kD... 29 3.6 gi|131011|sp|P10162|PR4L_HUMAN Basic salivary proline-rich ... 29 3.6 gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 4... 29 3.6 gi|20141192|sp|O60885|BRD4_HUMAN Bromodomain-containing pro... 29 3.6 gi|13123997|sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guan... 29 3.6 gi|18202099|sp|O60902|SHOX2_HUMAN Short stature homeobox pr... 29 3.6 gi|13432104|sp|P13942|CA2B_HUMAN Collagen alpha 2(XI) chain... 29 3.6 gi|52001471|sp|P10161|PR4M_HUMAN Basic salivary proline-ric... 29 3.6 gi|51315800|sp|Q9UPA5|BSN_HUMAN Bassoon protein (Zinc-finge... 29 3.6 gi|29337113|sp|Q96AJ9|VT1A_HUMAN Vesicle transport through ... 28 4.7 gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist... 28 4.7 gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense tra... 28 4.7 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 28 4.7 gi|3122058|sp|Q13201|MRN1_HUMAN Multimerin 1 precursor (End... 28 4.7 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 28 4.7 gi|547700|sp|Q01101|INSM1_HUMAN Zinc finger protein IA-1 (I... 28 4.7 gi|60390213|sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40-containi... 28 4.7 gi|52000732|sp|Q99700|ATX2_HUMAN Ataxin-2 (Spinocerebellar ... 28 4.7 gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense tra... 28 4.7 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 28 4.7 gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like pro... 28 4.7 gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-termin... 28 4.7 gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin ... 28 4.7 gi|29336893|sp|Q96DN6|MBD6_HUMAN Methyl-CpG-binding domain ... 28 4.7 gi|20177873|sp|Q9UQB3|CTD2_HUMAN Catenin delta-2 (Delta-cat... 28 4.7 gi|30580335|sp|O75167|PHR2_HUMAN Phosphatase and actin regu... 28 4.7 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 28 4.7 gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal... 28 4.7 gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain... 28 4.7 gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinas... 28 4.7 gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-... 28 4.7 gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonuc... 28 6.2 gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein ... 28 6.2 gi|1345650|sp|Q02388|CO7A1_HUMAN Collagen alpha 1(VII) chai... 28 6.2 gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal... 28 6.2 gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreduct... 28 6.2 gi|27805394|sp|O60641|AP180_HUMAN Clathrin coat assembly pr... 28 6.2 gi|1711641|sp|P17600|SYN1_HUMAN Synapsin-1 (Synapsin I) (Br... 28 6.2 gi|34098740|sp|Q9NYF0|DAC1_HUMAN Dapper homolog 1 (hDPR1) (... 28 6.2 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 28 6.2 gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa parane... 28 6.2 gi|6016211|sp|P78426|NK61_HUMAN Homeobox protein Nkx-6.1 28 6.2 gi|8928568|sp|Q12888|TP53B_HUMAN Tumor suppressor p53-bindi... 28 6.2 gi|57012964|sp|Q92922|SMRC1_HUMAN SWI/SNF-related matrix-as... 28 6.2 gi|29429203|sp|P54259|DRPLA_HUMAN Atrophin-1 (Dentatorubral... 28 6.2 gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia... 28 6.2 gi|38258268|sp|Q9UPQ9|K1093_HUMAN Protein KIAA1093 28 6.2 gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal... 28 8.1 gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 prot... 28 8.1 gi|135846|sp|P20962|PTMS_HUMAN Parathymosin 28 8.1 gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Vi... 28 8.1 gi|12229810|sp|Q9NYJ7|DLL3_HUMAN Delta-like protein 3 precu... 28 8.1 gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (... 28 8.1 gi|461675|sp|P29400|CA54_HUMAN Collagen alpha 5(IV) chain p... 28 8.1 gi|38372706|sp|Q8NGJ4|O52E2_HUMAN Olfactory receptor 52E2 28 8.1 gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 3... 28 8.1 gi|34098675|sp|Q96D71|REP1_HUMAN RalBP1 associated Eps doma... 28 8.1 gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated prot... 28 8.1 gi|6136124|sp|O75385|ULK1_HUMAN Serine/threonine-protein ki... 28 8.1 gi|29429200|sp|P53814|SMOO_HUMAN Smoothelin 28 8.1 gi|17433253|sp|Q9NZQ3|SP90_HUMAN SH3 adapter protein SPIN90... 28 8.1 gi|6686051|sp|O00294|TULP1_HUMAN Tubby related protein 1 (T... 28 8.1 gi|28380068|sp|Q14686|NCOA6_HUMAN Nuclear receptor coactiva... 28 8.1 gi|21263906|sp|Q99954|PRL5_HUMAN Proline-rich protein 5 pre... 28 8.1 gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment facto... 28 8.1 gi|46397803|sp|O60732|MGC1_HUMAN Melanoma-associated antige... 28 8.1 gi|1730095|sp|P52954|LBX1_HUMAN Transcription factor LBX1 28 8.1 gi|20141212|sp|P20849|CA19_HUMAN Collagen alpha 1(IX) chain... 28 8.1 gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) 28 8.1
>gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (Tropomyosin 3) (Tropomyosin gamma) Length = 284 Score = 184 bits (468), Expect = 4e-47 Identities = 101/144 (70%), Positives = 110/144 (76%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 MELQEIQLKEAKHIAEEADRKYEEV RKLVIIEGDLE TEERAELAES+C E +E+++ + Sbjct: 141 MELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNV 200 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 NLK L EKYSQKED YEEEIKILTDKLKEAETRAEF ER VAKLEKT DDLE +L Sbjct: 201 TNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDEL 260 Query: 121 KCNKEENLCTQRMLYQTLLDLNEI 144 K + L L D+ I Sbjct: 261 YAQKLKYKAISEELDHALNDMTSI 284
Score = 43.1 bits (100), Expect = 2e-04 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 82 E + +K+ +++ D E +RAE AE+ ++ +E+ + ++ L + + + D Y Sbjct: 2 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 61 Query: 83 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 130 E +K +KL+ AE +A E VA L + +E +L +E L T Sbjct: 62 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD-RAQERLAT 108
Score = 33.9 bits (76), Expect = 0.11 Identities = 26/127 (20%), Positives = 62/127 (48%), Gaps = 14/127 (11%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC-------TEERAELAESRCQETD 54 E E + K+A+ +++ + + + +KL E +L+ +E+ ELAE + + + Sbjct: 23 EQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAE 82 Query: 55 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 ++ +++ ++ + + + D +E + KL+EAE A+ +ER + +E Sbjct: 83 AEVASLNRRIQLVEE-------ELDRAQERLATALQKLEEAEKAADESERGMKVIENRAL 135 Query: 115 DLEYKLK 121 E K++ Sbjct: 136 KDEEKME 142
>gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain (Tropomyosin 4) (TM30p1) Length = 248 Score = 184 bits (466), Expect = 7e-47 Identities = 96/142 (67%), Positives = 115/142 (80%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ME+QE+QLKEAKHIAEEADRKYEEV RKLVI+EG+LE EERAE++E +C + +E+++ + Sbjct: 105 MEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNV 164 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 NLK L A EKYS+KED YEEEIK+L+DKLKEAETRAEF ER VAKLEKT DDLE KL Sbjct: 165 TNNLKSLEAASEKYSEKEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKL 224 Query: 121 KCNKEENLCTQRMLYQTLLDLN 142 KEEN+ + L QTL +LN Sbjct: 225 AQAKEENVGLHQTLDQTLNELN 246
Score = 33.9 bits (76), Expect = 0.11 Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 7/110 (6%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 E+A+ + R++ ++E +L+ +ER A + +E ++ ++ +K + + K Sbjct: 43 EKAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDE 102 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 125 +K +I E + LKEA+ AE +R ++ + LE +L+ +E Sbjct: 103 EKMEIQEMQ-------LKEAKHIAEEADRKYEEVARKLVILEGELERAEE 145
Score = 30.4 bits (67), Expect = 1.2 Identities = 22/99 (22%), Positives = 46/99 (46%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 82 E V RK+ ++ + E+RA+ + E+ + ++ L+ + ++ D + Sbjct: 8 EAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQ 67 Query: 83 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 E + KL+EAE A+ +ER + +E E K++ Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 106
>gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (Alpha-tropomyosin) Length = 284 Score = 171 bits (433), Expect = 5e-43 Identities = 91/144 (63%), Positives = 106/144 (73%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ME+QEIQLKEAKHIAE+ADRKYEEV RKLVIIE DLE EERAEL+E +C E +E+++ + Sbjct: 141 MEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTV 200 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 NLK L EKYSQKED YEEEIK+L+DKLKEAETRAEF ER V KLEK+ DDLE +L Sbjct: 201 TNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDEL 260 Query: 121 KCNKEENLCTQRMLYQTLLDLNEI 144 K + L L D+ I Sbjct: 261 YAQKLKYKAISEELDHALNDMTSI 284
Score = 38.5 bits (88), Expect = 0.005 Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 82 + + +K+ +++ D E +RAE AE+ + +++ + ++ L L + + D Y Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61 Query: 83 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 130 E +K +KL+ AE +A E VA L + +E +L +E L T Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD-RAQERLAT 108
Score = 32.7 bits (73), Expect = 0.25 Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 19/120 (15%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 EL +Q K+ K +E D KY E L+ +E+ ELAE + + + + ++ Sbjct: 42 ELVSLQ-KKLKGTEDELD-KYSEA----------LKDAQEKLELAEKKATDAEADVASLN 89 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + ++ + + + D +E + KL+EAE A+ +ER + +E E K++ Sbjct: 90 RRIQLVEE-------ELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKME 142
>gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin) Length = 284 Score = 167 bits (423), Expect = 7e-42 Identities = 89/152 (58%), Positives = 116/152 (76%), Gaps = 13/152 (8%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 MELQE+QLKEAKHIAE++DRKYEEV RKLVI+EG+LE +EERAE+AES+C + +E+++++ Sbjct: 141 MELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIV 200 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 NLK L +KYS KED YEEEIK+L +KLKEAETRAEF ER VAKLEKT DDL Sbjct: 201 TNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDL---- 256 Query: 121 KCNKEENLCTQRMLYQTLLD-----LNEISSV 147 E+ + Q+M Y+ + + LN+I+S+ Sbjct: 257 ----EDEVYAQKMKYKAISEELDNALNDITSL 284
Score = 45.4 bits (106), Expect = 4e-05 Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 15/115 (13%) Query: 23 EEVPRKLVIIEGDLECTEERAELAES-------RCQETDEQIRLMDQNLKCLSDAEEKYS 75 + + +K+ +++ D E +RAE AE+ RC++ +E+ + + + LK D EKYS Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 130 E +K +KL++AE +A E VA L + +E +L +E L T Sbjct: 62 -------ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELD-RAQERLAT 108
Score = 40.8 bits (94), Expect = 0.001 Identities = 36/159 (22%), Positives = 79/159 (49%), Gaps = 14/159 (8%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E QE +L++A+ A +A+ + R++ ++E +L+ +ER A + +E ++ + Sbjct: 66 EAQE-KLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESE 124 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + +K + + K +K ++ E + LKEA+ AE ++R ++ + LE +L+ Sbjct: 125 RGMKVIENRAMKDEEKMELQEMQ-------LKEAKHIAEDSDRKYEEVARKLVILEGELE 177 Query: 122 CNKE-----ENLCTQRMLYQTLLDLNEISSVSIQISNYS 155 ++E E+ C + + + N + S+ Q YS Sbjct: 178 RSEERAEVAESKCGD-LEEELKIVTNNLKSLEAQADKYS 215
Score = 36.2 bits (82), Expect = 0.023 Identities = 24/120 (20%), Positives = 59/120 (49%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E E K+A+ ++ + + + + +KL E ++E E + A+ + ++ +++ + Sbjct: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAE 82 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++ L+ + ++ D +E + KL+EAE A+ +ER + +E E K++ Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
>gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smooth muscle isoform (SMMHC) Length = 1972 Score = 50.1 bits (118), Expect = 2e-06 Identities = 56/232 (24%), Positives = 105/232 (45%), Gaps = 22/232 (9%) Query: 2 ELQEIQLKEAKHIAEEADR------KYEEVPRKLVIIEGDLECTEERAELAESRCQETDE 55 EL+EI + + EE DR + +++ ++++ +E LE E + + + Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +I+ ++ + + D K S++ + EE I LT L E E +A+ +L K E + Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038 Query: 116 LEYKLK---CNKEENLCTQRMLYQTLLDLNE-ISSVSIQISNYSFRGCCDDQN----KGR 167 LE +LK +++E +R L D +E I+ + QI+ + ++ R Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098 Query: 168 FDGPEAQEEACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQ 219 D AQ+ + + +EL + + + + L S R RN KA KQK+ Sbjct: 1099 LDDEIAQKN--NALKKIRELEGHISDLQEDLDSERAARN------KAEKQKR 1142
Score = 37.4 bits (85), Expect = 0.010 Identities = 26/121 (21%), Positives = 55/121 (45%), Gaps = 1/121 (0%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 M+LQE L A+ ++AD + EE+ +L ++ E+R + +E++ Sbjct: 1690 MQLQE-DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEE 1748 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 N++ +SD K +Q+ + E+ ++ E+ + ER +L ++E + Sbjct: 1749 QGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAV 1808 Query: 121 K 121 K Sbjct: 1809 K 1809
Score = 30.4 bits (67), Expect = 1.2 Identities = 57/260 (21%), Positives = 110/260 (42%), Gaps = 43/260 (16%) Query: 32 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS-DAEEKYSQKEDIYEEEIKILTD 90 +EGDL+ E +A+ A +E +Q+R + +K + E+ + +++I+ Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA-------- 1673 Query: 91 KLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQ 150 KE E +A+ E A L + +DL + K+ +L + + + Sbjct: 1674 TAKENEKKAKSLE---ADLMQLQEDLAAAERARKQADLEKEELAEEL------------- 1717 Query: 151 ISNYSFRGCCDDQNKGRFDGPEAQ-EEACSGERTYQELLVNQ--------NPIVQPLASR 201 S+ S R D+ K R + AQ EE E+ E + ++ + LA+ Sbjct: 1718 ASSLSGRNALQDE-KRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE 1776 Query: 202 RLTRNLYKCIKKAMKQ--KQLRRGVKEVQKFV-NKGEKGIMVLAEDTLPIEEVLGPEALF 258 R T + ++ +++ K+LR + E++ V +K + I L +EE + EA Sbjct: 1777 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA-- 1834 Query: 259 GRVRWRPGAAQTAPQEPSKL 278 R + A ++ Q+ KL Sbjct: 1835 ---REKQAATKSLKQKDKKL 1851
Score = 28.1 bits (61), Expect = 6.2 Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 9/122 (7%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E Q +L+ H E A + + + +E + EE+ E Q + ++ Sbjct: 1790 LERQNKELRSKLHEMEGAVKS--KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQK 1847 Query: 61 DQNLK-CLSDAE------EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 113 D+ LK L E E+Y ++ + +K L +L+EAE ++ KL++ Sbjct: 1848 DKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907 Query: 114 DD 115 D+ Sbjct: 1908 DE 1909
Score = 28.1 bits (61), Expect = 6.2 Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q++E + + +R E+ K+ ++ ++E AE + + + + + L Sbjct: 1258 EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1317 Query: 65 KCLSDA-EEKYSQKEDI------YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 + + +E+ QK ++ EEE L D+L E + ER ++ L D + Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377 Query: 118 YKLK 121 KL+ Sbjct: 1378 KKLQ 1381
>gi|2500345|sp|P55769|NHPX_HUMAN NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) ([U4/U6.U5] tri-snRNP 15.5 kDa protein) (OTK27) Length = 128 Score = 48.5 bits (114), Expect = 4e-06 Identities = 23/61 (37%), Positives = 35/61 (57%) Query: 192 NPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEV 251 NP PLA LT+ L ++++ KQLR+G E K +N+G +V+A D P+E + Sbjct: 7 NPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEII 66 Query: 252 L 252 L Sbjct: 67 L 67
>gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit associated protein 2 (CDK5 activator-binding protein C48) Length = 1893 Score = 47.0 bits (110), Expect = 1e-05 Identities = 53/237 (22%), Positives = 101/237 (42%), Gaps = 33/237 (13%) Query: 14 IAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK 73 + +E DR EE+ L E ++C +E E ++ C DE + + C + EEK Sbjct: 215 VLDEKDRLIEELKLSLKSKEALIQCLKE--EKSQMACP--DENVSSGELRGLCAAPREEK 270 Query: 74 ----------YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 + ++ + +EE I+ L + L+E E ++ K +K L LK Sbjct: 271 ERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSK 330 Query: 124 KEENLCTQRMLYQTLLDLN-EISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGER 182 +++ + +LN EI +S + R F G E E A SG+ Sbjct: 331 EKK-----------VEELNSEIEKLSAAFA--KAREALQKAQTQEFQGSEDYETALSGKE 377 Query: 183 TYQELLVNQNPIVQPLASRRLTRNLYKCIKK----AMKQKQLRRGVKEVQKFVNKGE 235 L +QN + + + RL R++ K ++ ++++L + ++E + +KG+ Sbjct: 378 ALSAALRSQN-LTKSTENHRLRRSIKKITQELSDLQQERERLEKDLEEAHREKSKGD 433
>gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin) Length = 1855 Score = 44.3 bits (103), Expect = 8e-05 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 24/163 (14%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEG--------------DLECTEERAELAESRC 50 E ++ + + +E ++ Y+ + KL +EG L+ +EE A++A R Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985 Query: 51 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAET-----RAEFTERL 105 E+I + ++L+ ++ + D Y++E + L LKE T + R+ Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045 Query: 106 VAKLEKTTDDLEYKL---KCNKEENLCTQRMLYQTLLDLNEIS 145 V + ++ T+ +E KL E +L +R+ YQ L LNE S Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNL--LNEFS 1086
>gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein (Centromere protein F) (Mitosin) (AH antigen) Length = 3210 Score = 43.5 bits (101), Expect = 1e-04 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 9/138 (6%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QLKE++H A+ + E + R+L I + E AE ++ + +I M Q+L+ Sbjct: 2419 QLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRG 2478 Query: 67 LS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 125 L D S+KED LT++L++ + R E + + E + E + KE Sbjct: 2479 LELDVVTIRSEKED--------LTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2530 Query: 126 ENLCTQRMLYQTLLDLNE 143 ++ ML L +LNE Sbjct: 2531 KSSTAMEMLQTQLKELNE 2548
Score = 39.7 bits (91), Expect = 0.002 Identities = 30/142 (21%), Positives = 67/142 (47%), Gaps = 3/142 (2%) Query: 5 EIQLKEAKHIAE---EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E K+ HIAE E +R+ + + K+ +E +L+ +EE EL + + ++ + Sbjct: 2225 EADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLK 2284 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++ ++ + + + E + LT +++E + + ++L++ + ++ E Sbjct: 2285 TQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEI 2344 Query: 122 CNKEENLCTQRMLYQTLLDLNE 143 KEE+ ML L +LNE Sbjct: 2345 QIKEESKTAVEMLQNQLKELNE 2366
Score = 35.8 bits (81), Expect = 0.030 Identities = 43/223 (19%), Positives = 90/223 (40%), Gaps = 56/223 (25%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 ++A KY + +KL + DL C + AE A RC E+K Sbjct: 351 DQASTKYTALEQKLKKLTEDLSCQRQNAESA--RC------------------SLEQKIK 390 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLY 135 +KE ++EE+ + + F +T D ++K + L + ++ Sbjct: 391 EKEKEFQEEL---------SRQQRSF---------QTLDQECIQMKARLTQELQQAKNMH 432 Query: 136 QTL-LDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPI 194 L +L++++SV Q+ N + E +++ C E+ +Q + +N + Sbjct: 433 NVLQAELDKLTSVKQQLEN---------------NLEEFKQKLCRAEQAFQASQIKENEL 477 Query: 195 VQPLASRRLTRNLYK--CIKKAMKQKQLRRGVKEVQKFVNKGE 235 + + + NL K +KA + L +K +++ +N+ + Sbjct: 478 RRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ 520
Score = 32.7 bits (73), Expect = 0.25 Identities = 34/145 (23%), Positives = 57/145 (39%), Gaps = 12/145 (8%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELAESRCQETDEQIRL 59 ME+ + QLKE E K + +EC E E+A+L + E + Sbjct: 2536 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQG-LDEAKNNYIV 2594 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEI----------KILTDKLKEAETRAEFTERLVAKL 109 + ++ L E QK + +EEI + L KL + E + + +L Sbjct: 2595 LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLEL 2654 Query: 110 EKTTDDLEYKLKCNKEENLCTQRML 134 T +LE K++ + +N Q L Sbjct: 2655 RNLTVELEQKIQVLQSKNASLQDTL 2679
Score = 32.0 bits (71), Expect = 0.43 Identities = 33/138 (23%), Positives = 63/138 (45%), Gaps = 18/138 (13%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 67 LK I EE + + + + ++ + E + + +L C++ +E+ ++ + L L Sbjct: 2856 LKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL 2915 Query: 68 SDAEEK------YSQKEDIYEEEIKILTDKLKEAETRA-EFTERLVA------KLEKTTD 114 A+EK K D EIK L + L+E A E+ ++ + KLEK + Sbjct: 2916 QAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKE 2975 Query: 115 DLEYKLKCNKEENLCTQR 132 LE ++ +LC+Q+ Sbjct: 2976 MLETQV-----AHLCSQQ 2988
Score = 30.4 bits (67), Expect = 1.2 Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 12/111 (10%) Query: 2 ELQEIQLKE-AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 E EIQ+KE +K E + +E+ + + GD E + + + +E + Q+R Sbjct: 2340 EQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE-EHQLRNS 2398 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 111 + L+ +A+EK +++ +L +LKE+E A+ + V LE+ Sbjct: 2399 IEKLRARLEADEK---------KQLCVL-QQLKESEHHADLLKGRVENLER 2439
Score = 28.1 bits (61), Expect = 6.2 Identities = 51/261 (19%), Positives = 102/261 (39%), Gaps = 42/261 (16%) Query: 2 ELQEIQLKEA--KHIAEEADRKYEEVPRKLVIIEGDLE-------CTEERAELAESRCQE 52 EL I+ ++A +H A + E V + + +E D E C EE + S + Sbjct: 1999 ELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQ 2058 Query: 53 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE-------IKILTDKLKEAETRAEFTERL 105 ++ M + L EK +K E I++ ++KE + Sbjct: 2059 LRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSD 2118 Query: 106 VAKLEKTTDDLEYKLKCNKEENLC---TQRMLYQTLLDLNEISSVSIQISNYSFRGCCDD 162 V++L K L+ KL+ ++++ T+ L + LN+ + ++ S + Sbjct: 2119 VSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKES---------E 2169 Query: 163 QNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRR 222 + R E+ E + + + LV + L+S + + QLRR Sbjct: 2170 SLQARLS--ESDYEKLNVSKALEAALVEKGEFALRLSSTQ------------EEVHQLRR 2215 Query: 223 GVKEVQKFVNKGEKGIMVLAE 243 G+++++ + EK + +AE Sbjct: 2216 GIEKLRVRIEADEKKQLHIAE 2236
>gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta) Length = 1935 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 14/125 (11%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 62 L + +L+E + + E+ +R RKL E +L T ER +L S+ Q + MD Sbjct: 1680 LLQAELEELRAVVEQTERS-----RKLA--EQELIETSERVQLLHSQNTSLINQKKKMDA 1732 Query: 63 NLKCL-SDAEEKYSQKEDIYEEEIKILTD------KLKEAETRAEFTERLVAKLEKTTDD 115 +L L ++ EE + + E+ K +TD +LK+ + + ER+ +E+T D Sbjct: 1733 DLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1792 Query: 116 LEYKL 120 L+++L Sbjct: 1793 LQHRL 1797
Score = 42.4 bits (98), Expect = 3e-04 Identities = 30/117 (25%), Positives = 56/117 (47%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q+ + + E+ + ++ R +EGDL+ T+E E+ Q+ DE+++ D L Sbjct: 1028 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFEL 1087 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L+ E ++++K L +++E E E AK+EK DL +L+ Sbjct: 1088 NALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELE 1144
Score = 35.4 bits (80), Expect = 0.039 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE E+ + E+ K +E EC+E + ++ E T+ Sbjct: 916 EAKVKEMNERLEDEEEMNAELTAKKRKLED--ECSELKRDIDDLELTLAKVEKEKHATEN 973 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 974 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDD 1033 Query: 116 LEYKLKCNKEENLCTQR 132 LE L+ K+ + +R Sbjct: 1034 LEGSLEQEKKVRMDLER 1050
Score = 32.0 bits (71), Expect = 0.43 Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 22/135 (16%) Query: 7 QLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEER-------AELAESRCQETDEQIR 58 +L EA+ IA + +K +++ ++ +E +LE ++R +E R +E Q Sbjct: 1796 RLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTE 1855 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFTER 104 +NL L D +K K Y+ + + + +L EAE RA+ E Sbjct: 1856 EDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAES 1915 Query: 105 LVAKLEKTTDDLEYK 119 V KL + D+ K Sbjct: 1916 QVNKLRAKSRDIGTK 1930
Score = 31.6 bits (70), Expect = 0.56 Identities = 30/130 (23%), Positives = 58/130 (44%), Gaps = 4/130 (3%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLE----CTEERAELAESRCQETDEQ 56 M+ + +LKEA +E ++ EE L+ + DL+ ++ AE RC + + Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 ++ +K +++ E + + + L D+ E + + E +AK+EK Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971 Query: 117 EYKLKCNKEE 126 E K+K EE Sbjct: 972 ENKVKNLTEE 981
Score = 30.4 bits (67), Expect = 1.2 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QL++ K EE + + L D + E+ E +ET+ + L K Sbjct: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE------EETEAKAELQRVLSKA 1364 Query: 67 LSDAEE---KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 S+ + KY Q+ + EE K L +L+EAE E + LEKT L+ + Sbjct: 1365 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424 Query: 120 LK 121 ++ Sbjct: 1425 IE 1426
Score = 29.3 bits (64), Expect = 2.8 Identities = 15/45 (33%), Positives = 28/45 (62%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 49 ++++K K AEEA+ + K ++ +L+ EERA++AES+ Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916
>gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory factor (TMF) Length = 1093 Score = 42.4 bits (98), Expect = 3e-04 Identities = 77/331 (23%), Positives = 130/331 (39%), Gaps = 61/331 (18%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD---------EQIRLMDQNLKC 66 E A+ K EEV LVI + E E C++ D E ++D+ + Sbjct: 371 ESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQ 430 Query: 67 LSDAE---EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 AE E S+KED+ + ++ L +KL++ E + + A LE+ D+L+ ++ Sbjct: 431 CEPAESQPEALSEKEDVC-KTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRV 489 Query: 124 KEENLC--------TQRML---YQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPE 172 KEE+ TQR+ + L E + +I N + D + Sbjct: 490 KEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLNSSETADLLK 549 Query: 173 AQEEAC-----SGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMK----------- 216 ++E GE+ ++ L N N I + A + N+ + K +K Sbjct: 550 EKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKELEEELQHLKQ 609 Query: 217 --------QKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAA 268 +KQ R +K++ V + EK + L D +EE + R A Sbjct: 610 VLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEE---------KNRSIQAAL 660 Query: 269 QTAPQEPSKLGDAGRKK----REASLSPETK 295 +A +E + L A K +EA+LS E K Sbjct: 661 DSAYKELTDLHKANAAKDSEAQEAALSREMK 691
Score = 35.4 bits (80), Expect = 0.039 Identities = 58/256 (22%), Positives = 110/256 (42%), Gaps = 31/256 (12%) Query: 15 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 74 A++++ + + R++ E +L E+A+ E+R Q+ I++ D L L E+ Sbjct: 676 AKDSEAQEAALSREMKAKE-ELSAALEKAQ-EEARQQQETLAIQVGDLRL-ALQRTEQAA 732 Query: 75 SQKEDIYEEEIKILTDKLKEAETRAE---------------FTERLVAKLEKTTDDLEYK 119 ++KED EI L +L+EAE R + E L A L T E K Sbjct: 733 ARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSWE-K 791 Query: 120 LKCNKEENLCTQRMLYQTLLD-----LNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQ 174 L+ N + L + L ++ E+ + IQ+S+ + Q RF +AQ Sbjct: 792 LEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQENSRF---QAQ 848 Query: 175 EEACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKG 234 E+ E+ L ++N Q + L + +++ K+K L E+++ + Sbjct: 849 LES---EKNRLCKLEDENNRYQ-VELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQ 904 Query: 235 EKGIMVLAEDTLPIEE 250 E+ + ++T+ +E Sbjct: 905 ERKKAIFTQETIKEKE 920
>gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of chromosome 2-like 1 protein (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) (PRO0324) Length = 1197 Score = 42.4 bits (98), Expect = 3e-04 Identities = 32/154 (20%), Positives = 67/154 (43%), Gaps = 20/154 (12%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD-----------LECTEERAELAESR 49 +E E LK K I +A+ KYE + K+ E + L+C + +A+ + + Sbjct: 752 IEESEETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKK 811 Query: 50 CQETDEQIRLMDQNLKCLSDAEEKYSQKEDI-------YEEEIKILTDKLKEAETRAEFT 102 +E +++ + L+ L Y Q+ + YE +I+++ ++ + + Sbjct: 812 MKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKA 871 Query: 103 ERLVAKLEK--TTDDLEYKLKCNKEENLCTQRML 134 + V K ++ T D KL K +N ++ M+ Sbjct: 872 QEEVTKQKEVITAQDTVIKLNMQKWQNTRSKTMI 905
Score = 34.7 bits (78), Expect = 0.066 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%) Query: 5 EIQLKEAKHIA-EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD--EQIRLMD 61 E+++KE + A EE + K ++ E E A+L +++ Q++ +Q +D Sbjct: 687 ELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELD 746 Query: 62 QNLKCLSDAEEKYSQKEDIY---EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 K + ++EE ++I EE+ ++L +K+K AE A+ E+ D + Sbjct: 747 ALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAE----------AERERELKDAQK 796 Query: 119 KLKCNK 124 KL C K Sbjct: 797 KLDCAK 802
Score = 28.5 bits (62), Expect = 4.7 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 9/107 (8%) Query: 20 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQK-- 77 ++ ++V +L I E +L EE ELA + T E+ R + Q + ++ + K Sbjct: 679 QELKDVQDELRIKENELRALEE--ELAGLK--NTAEKYRQLKQQWEMKTEEADLLQTKLQ 734 Query: 78 EDIY---EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + Y +EE+ L ++E+E + T+ + K E+ + LE K+K Sbjct: 735 QSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMK 781
>gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha) Length = 1939 Score = 42.0 bits (97), Expect = 4e-04 Identities = 35/125 (28%), Positives = 63/125 (50%), Gaps = 14/125 (11%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 62 L + +L+E + + E+ +R RKL E +L T ER +L S+ Q + M+ Sbjct: 1682 LLQAELEELRAVVEQTERS-----RKLA--EQELIETSERVQLLHSQNTSLINQKKKMEA 1734 Query: 63 NLKCL-SDAEEKYSQKEDIYEEEIKILTD------KLKEAETRAEFTERLVAKLEKTTDD 115 +L L S+ EE + + E+ K +TD +LK+ + + ER+ +E+T D Sbjct: 1735 DLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKD 1794 Query: 116 LEYKL 120 L+++L Sbjct: 1795 LQHRL 1799
Score = 39.3 bits (90), Expect = 0.003 Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 22/142 (15%) Query: 7 QLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEER-------AELAESRCQETDEQIR 58 +L EA+ IA + +K +++ ++ +EG+LE ++R +E R +E Q Sbjct: 1798 RLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTE 1857 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFTER 104 +NL L D +K K Y+ + + + +L EAE RA+ E Sbjct: 1858 EDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAES 1917 Query: 105 LVAKLEKTTDDLEYKLKCNKEE 126 V KL + D+ K K + EE Sbjct: 1918 QVNKLRAKSRDIGAKQKMHDEE 1939
Score = 35.0 bits (79), Expect = 0.050 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE E+ + E+ K +E EC+E + ++ E T+ Sbjct: 918 EAKVKEMNERLEDEEEMNAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 975 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 976 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035 Query: 116 LEYKLKCNKEENLCTQR 132 LE L+ K+ + +R Sbjct: 1036 LEGSLEQEKKVRMDLER 1052
Score = 29.3 bits (64), Expect = 2.8 Identities = 15/45 (33%), Positives = 28/45 (62%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 49 ++++K K AEEA+ + K ++ +L+ EERA++AES+ Sbjct: 1874 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
Score = 29.3 bits (64), Expect = 2.8 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 Q+++ K EE + + L D + E+ E +ET+ + L K Sbjct: 1313 QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYE------EETEAKAELQRVLSKA 1366 Query: 67 LSDAEE---KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 S+ + KY Q+ + EE K L +L++AE E + LEKT L+ + Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE 1426 Query: 120 LK 121 ++ Sbjct: 1427 IE 1428
Score = 29.3 bits (64), Expect = 2.8 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 7/122 (5%) Query: 12 KHIAEEADRKYEEVPRKLVII---EGDLE----CTEERAELAESRCQETDEQIRLMDQNL 64 K E+++ + +E+ K+V + + DL+ ++ AE RC + + ++ + Sbjct: 862 KETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKV 921 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 K +++ E + + + L D+ E + + E +AK+EK E K+K Sbjct: 922 KEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 981 Query: 125 EE 126 EE Sbjct: 982 EE 983
>gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motility receptor (Intracellular hyaluronic acid binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen) Length = 724 Score = 42.0 bits (97), Expect = 4e-04 Identities = 50/222 (22%), Positives = 103/222 (46%), Gaps = 16/222 (7%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE-RAELAESRCQETDEQIR---LM 60 E+Q + K I E+ +R E++ +K + I+ L+ +E + L + C +E ++ L Sbjct: 317 EMQNLKQKFILEQQER--EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLF 374 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 ++ LK D +K QKE+ E +K L + EA++RAE + L KL+ +LE Sbjct: 375 EEELKQTLDELDKLQQKEEQAERLVKQLEE---EAKSRAEELKLLEEKLKGKEAELEKSS 431 Query: 121 KCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSG 180 + + L Q Y ++ + + V+ Q +Y + ++ + + QE+A Sbjct: 432 AAHTQATLLLQEK-YDSM--VQSLEDVTAQFESYKALTASEIEDL-KLENSSLQEKAAKA 487 Query: 181 ERTYQELLVNQNPIVQPLASRRLTRNLYKC-IKKAMKQKQLR 221 + ++ V + +++ R L K A+K+ +++ Sbjct: 488 GKNAED--VQHQILATESSNQEYVRMLLDLQTKSALKETEIK 527
Score = 41.6 bits (96), Expect = 5e-04 Identities = 58/253 (22%), Positives = 111/253 (43%), Gaps = 34/253 (13%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E E++L+ + EE+ K ++ KLV IE E +E++E T++ + ++ Sbjct: 189 EGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEK--EKIDEKSE--------TEKLLEYIE 238 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK-- 119 + + C SD EKY EE +K +K E + + E + L K +DL K Sbjct: 239 E-ISCASDQVEKYKLDIAQLEENLK---EKNDEILSLKQSLEENIVILSKQVEDLNVKCQ 294 Query: 120 -LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPE------ 172 L+ KE+++ R + NE +++ ++ N + + Q + + E Sbjct: 295 LLEKEKEDHVNRNR-------EHNE--NLNAEMQNLKQKFILEQQEREKLQQKELQIDSL 345 Query: 173 AQEEACSGERTYQELLVNQNPIVQP--LASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKF 230 Q+E +Q+L Q +V+ L L + L + K K++Q R VK++++ Sbjct: 346 LQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEE 405 Query: 231 VNKGEKGIMVLAE 243 + + +L E Sbjct: 406 AKSRAEELKLLEE 418
Score = 40.0 bits (92), Expect = 0.002 Identities = 25/111 (22%), Positives = 58/111 (52%), Gaps = 3/111 (2%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 E + + + + +K ++ + + E +++ +S Q+ E + Q L +E+ Sbjct: 312 ENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKL---CSFQEEMV 368 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 ++++++EEE+K D+L + + + E ERLV +LE+ +LK +E+ Sbjct: 369 KEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEK 419
>gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X Length = 2058 Score = 42.0 bits (97), Expect = 4e-04 Identities = 45/188 (23%), Positives = 78/188 (41%), Gaps = 15/188 (7%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQET--DEQIRLMDQNL 64 QL K EE ++ EE +K E + E AEL + +ET +++ + ++ Sbjct: 810 QLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQ 869 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV--AKLEKTTDDLEYKLKC 122 K E QKE+ EEI L ++++ + E E + A L+K + + +L+ Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR- 928 Query: 123 NKEENLCTQRMLYQTLLDLNEIS----------SVSIQISNYSFRGCCDDQNKGRFDGPE 172 EE C + L+ +EI SV + S+ C+++ F P Sbjct: 929 RLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPY 988 Query: 173 AQEEACSG 180 +EE G Sbjct: 989 PEEEVDEG 996
>gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmuscle type B (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 41.6 bits (96), Expect = 5e-04 Identities = 35/131 (26%), Positives = 62/131 (47%), Gaps = 8/131 (6%) Query: 2 ELQEIQLKEAKHIAEEADRKY--EEVPRKLVIIEGDLECTEERAELAESRCQ----ETDE 55 EL+EI + EE +R + +K+ DLE + E A + Q + Sbjct: 919 ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEA 978 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +I+ M++ + L D K+ +++ + E+ I + +L E E +A+ ++ K E D Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038 Query: 116 LEYKLKCNKEE 126 LE +LK KEE Sbjct: 1039 LEERLK--KEE 1047
Score = 35.8 bits (81), Expect = 0.030 Identities = 47/256 (18%), Positives = 102/256 (39%), Gaps = 16/256 (6%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 +L + EEA++K + + +E L+ T+E + + +IR +++ Sbjct: 1288 ELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNS 1347 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA-------EFTERLVAKLEKTTDDLEYK 119 L + +E+ + E+++ L +L + + + E E KL K + L + Sbjct: 1348 LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407 Query: 120 LKCNKEENLCTQRMLYQTLLDL-NEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEAC 178 L EE L +T L E+ +++ + + ++ + +FD A+E++ Sbjct: 1408 L----EEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI 1463 Query: 179 SG----ERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKG 234 S ER E + +R L L + + KQLR ++++ + Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523 Query: 235 EKGIMVLAEDTLPIEE 250 K + L + +E+ Sbjct: 1524 GKNVHELEKSKRALEQ 1539
Score = 34.7 bits (78), Expect = 0.066 Identities = 45/195 (23%), Positives = 88/195 (45%), Gaps = 10/195 (5%) Query: 2 ELQEIQLKEAKHIAE--EADRKYEEVPRKLVIIEGDLEC-TEERAELAESRCQETDEQIR 58 EL +++ K+ K E E +RK++++ + I+ L+ TE AE E R + ++ Sbjct: 860 ELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQE 919 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 L ++ L L E+ ++ I + E K + +++ E + + E KL+ E Sbjct: 920 L-EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEA 978 Query: 119 KLKCNKEENLCTQ----RMLYQTLLDLNEISSVSIQIS--NYSFRGCCDDQNKGRFDGPE 172 K+K +EE L + + + + L + I+ S Q++ + +NK + Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038 Query: 173 AQEEACSGERTYQEL 187 +E E+T QEL Sbjct: 1039 LEERLKKEEKTRQEL 1053
Score = 32.7 bits (73), Expect = 0.25 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 30/172 (17%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLV-----IIEGDLECTEERAELAESRCQETDE 55 +E + +QL+E +E A R E+ +L G +E+ L E+R + +E Sbjct: 1685 LEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL-EARIAQLEE 1743 Query: 56 QIRLMDQNLKCLSD-----------------AEEKYSQKEDIYEEEI----KILTDKLKE 94 ++ N++ L+D AE +QK D +++ K L KL+E Sbjct: 1744 ELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQE 1803 Query: 95 AE--TRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEI 144 E +++F + ++ LE LE +L+ +E +++ +T L EI Sbjct: 1804 LEGAVKSKF-KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1854
Score = 32.3 bits (72), Expect = 0.33 Identities = 28/114 (24%), Positives = 52/114 (45%), Gaps = 12/114 (10%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 Q++QL++ A+ K +++ +++++E + +L E R E Q+ ++ Sbjct: 967 QKLQLEKVT-----AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK 1021 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 K L+ K EE +K KE +TR E E+ KL+ T DL+ Sbjct: 1022 AKNLAKIRNKQEVMISDLEERLK------KEEKTRQEL-EKAKRKLDGETTDLQ 1068
Score = 31.6 bits (70), Expect = 0.56 Identities = 23/115 (20%), Positives = 49/115 (42%) Query: 6 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 65 +Q+ + + D + +V K +EG+LE E + + EQ++ + Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904 Query: 66 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 + + + K+ EE + L +++E E R + + K++ DLE +L Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Score = 30.8 bits (68), Expect = 0.95 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 9/93 (9%) Query: 47 ESRCQETDEQI-RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK-EAETRAEFTE- 103 E Q DE++ ++ ++ K + EE + + + EE+ IL ++L+ E E AE E Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK-NILAEQLQAETELFAEAEEM 909 Query: 104 --RLVAK---LEKTTDDLEYKLKCNKEENLCTQ 131 RL AK LE+ DLE +++ +E N Q Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Score = 30.4 bits (67), Expect = 1.2 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 14/127 (11%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVI-----IEGDLECTEERAELAESRCQETDEQ 56 E + + +K+ + + EA+ + E R L + +E DL+ E + E A E +Q Sbjct: 1589 EKKRLLIKQVREL--EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646 Query: 57 IRLMDQNLKCLS-DAEEKYSQKEDIY------EEEIKILTDKLKEAETRAEFTERLVAKL 109 +R + +K + EE + +++I+ E+++K L ++ + + +ER Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706 Query: 110 EKTTDDL 116 E+ D+L Sbjct: 1707 EQERDEL 1713
Score = 27.7 bits (60), Expect = 8.1 Identities = 23/107 (21%), Positives = 48/107 (44%), Gaps = 3/107 (2%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 ++ + E+ + +E +E + E E Q T++ ++ N++ + E+ Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580 Query: 76 QKEDIYEEEIK-ILTDKLK--EAETRAEFTERLVAKLEKTTDDLEYK 119 Q D EE K +L +++ EAE E +R +A K +++ K Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
>gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9 (Protein kinase A anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120 like protein) (Hyperion protein) (Yotiao protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) Length = 3911 Score = 41.6 bits (96), Expect = 5e-04 Identities = 67/295 (22%), Positives = 132/295 (44%), Gaps = 45/295 (15%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 +L+E H E R E++ +L EG ++ + L E + QE + I ++Q L C Sbjct: 1910 ELRERLH---EESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLC 1966 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA--------EFTERLV-------AKLEK 111 S+ ++ ++ +EE ++L+ + + + A + TE+L+ + EK Sbjct: 1967 ASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEK 2026 Query: 112 TTDDLEYKLKC---NKEENLCTQRMLYQ----TLLDLNEISSVSIQISNYSFRGCCDDQN 164 DDL+ ++K + EE + L Q L+DL + + +++ R D+Q Sbjct: 2027 VRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQ-QNQALEKQLEKMRKFLDEQA 2085 Query: 165 KGR-FDGPEAQEEACSGER------TYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQ 217 R + Q+E E+ +Q + +Q V+ LA+ L KC + + + Sbjct: 2086 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLAN-HLKEKTDKCSELLLSK 2144 Query: 218 KQLRRGV----KEVQKF---VNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRP 265 +QL+R + +E++K V + E+ ++V A+ +E+ FG V +P Sbjct: 2145 EQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVED----RKHFGAVEAKP 2195
Score = 37.4 bits (85), Expect = 0.010 Identities = 61/281 (21%), Positives = 121/281 (43%), Gaps = 41/281 (14%) Query: 9 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL- 67 KE ++ E+ ++ EE+ K ++ E + + + +R QE +++ +L +++ L Sbjct: 2215 KEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLG 2274 Query: 68 -----SDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD-------- 114 SDA Q ++ + +I+ +K E + E +L +L+ TTD Sbjct: 2275 LAIKESDAMSTQDQHV-LFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKN 2333 Query: 115 ----DLEYKLKCNKEENLCTQRMLYQTLLDLNE-ISSVSIQISNYSFRGCCDDQNKGRFD 169 DLE +++C + C +R + + LNE I + +++N K + Sbjct: 2334 ELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIG--------QKTSMN 2385 Query: 170 GPEAQEEACSGERTYQELLVNQNPIVQPL--ASRRLT--RNLYKCIKKAMKQK-----QL 220 EEA S + ++ + + Q + A+ +T +N+ K M Q L Sbjct: 2386 AHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSL 2445 Query: 221 RRGVKEVQKFVNKGEKGIMV----LAEDTLPIEEVLGPEAL 257 +R + V+K + E + V L++D +E VL +AL Sbjct: 2446 KRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 2486
Score = 36.6 bits (83), Expect = 0.017 Identities = 68/284 (23%), Positives = 114/284 (40%), Gaps = 50/284 (17%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 +EIQ KE I EE + K E +K + ++ ++ A+ E EQI +Q Sbjct: 334 EEIQEKET--IIEELNTKIIEEEKKTLELK-------DKLTTADKLLGELQEQIVQKNQE 384 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR----AEFTERLVAKLEKTTDDLEYK 119 +K + QKE EEIK L ++E + R ++F +V ++E+ Sbjct: 385 IKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQE------- 437 Query: 120 LKCNKEENLCTQRMLYQTLLDLNEISSVSI-QISNYSFRGCCDDQNKGRFDGPEAQEEAC 178 TQR L Q +L+E+ I Q+ R + + E A Sbjct: 438 ----------TQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENAL 487 Query: 179 SGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGI 238 R+Y + VN++ I K + A+ + ++ QK K E G+ Sbjct: 488 ---RSYSNITVNEDQI--------------KLMNVAINELNIKLQDTNSQKEKLKEELGL 530 Query: 239 MVLAEDTLPIE-EVLGPEALFGRVRWRPGAAQTAPQEPSKLGDA 281 ++ + L + E L E F R + + A QT ++ SKL +A Sbjct: 531 ILEEKCALQRQLEDLVEELSFSREQIQ-RARQTIAEQESKLNEA 573
Score = 30.0 bits (66), Expect = 1.6 Identities = 34/153 (22%), Positives = 71/153 (46%), Gaps = 23/153 (15%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 ++ E+Q+ E + + A E++ + +++ E ++ELA+++ E + ++ Sbjct: 3136 QMLEMQV-ELSSMKDRATELQEQLSSEKMVV------AELKSELAQTKL-ELETTLKAQH 3187 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE----FTERLVAKLEKTTD--- 114 ++LK L + K D E+ +L D L + ++ E+ AKL ++ + Sbjct: 3188 KHLKELEAFRLEVKDKTD----EVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDK 3243 Query: 115 ----DLEYKLKCNKEENLCTQRMLYQTLLDLNE 143 DL++ L+ K+ NL +L Q LNE Sbjct: 3244 EELEDLKFSLESQKQRNLQLNLLLEQQKQLLNE 3276
>gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) Length = 2871 Score = 41.6 bits (96), Expect = 5e-04 Identities = 49/240 (20%), Positives = 108/240 (45%), Gaps = 20/240 (8%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAEL---------AESRCQETDEQI 57 L +A ++ +++ E + + + D +C E E A L A S ET ++ Sbjct: 1469 LDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKL 1528 Query: 58 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 ++ +Q L L E+ SQ+ + +++I + LKE + + + E + +L++T + Sbjct: 1529 KVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDS 1588 Query: 118 YKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCD-DQNKGRFDGPEAQEE 176 K K +EE +R L + + + ++ Q S R D Q + DG ++ Sbjct: 1589 CKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREK- 1647 Query: 177 ACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKA-MKQKQLRRGVKEVQKFVNKGE 235 +RT +EL + + A RR + +K+A ++ + ++ +++ + +N+ + Sbjct: 1648 ----QRTQEELRRLSSEVE---ALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESK 1700
Score = 35.8 bits (81), Expect = 0.030 Identities = 51/237 (21%), Positives = 98/237 (41%), Gaps = 48/237 (20%) Query: 9 KEAKHIAEEADR---KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 65 +E + ++EE R + L +E D++ + R Q+ + ++R + Q Sbjct: 1400 RENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQ--- 1456 Query: 66 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 125 EE K+ + ++ K + DK KE E RL ++K T+D KC ++ Sbjct: 1457 --MRTEESVRYKQSL-DDAAKTIQDKNKEIE-------RLKQLIDKETNDR----KCLED 1502 Query: 126 ENLCTQRMLY----------QTLLDL----NEISSVSIQISNYSFRGCCDDQNKGRFDGP 171 EN QR+ Y +T+ L E++ + I S DQ+ RF Sbjct: 1503 ENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRF--- 1559 Query: 172 EAQEEACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQ--KQLRRGVKE 226 + + +EL + + + + L + T + C +K +++ + +RR +KE Sbjct: 1560 ---------QNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKE 1607
>gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (SB1.8/DXS423E protein) (Sb1.8) Length = 1233 Score = 41.2 bits (95), Expect = 7e-04 Identities = 30/122 (24%), Positives = 65/122 (53%), Gaps = 8/122 (6%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD----EQ 56 + L+E Q+K+ + EEA ++ + ++L D + ++R +L E + ET+ ++ Sbjct: 365 LTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQK 424 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKI---LTDKLKEAETRA-EFTERLVAKLEKT 112 +R +++N K + EE + + EE+ K+ LT++++ A+ R E + L +E+ Sbjct: 425 LREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQL 484 Query: 113 TD 114 D Sbjct: 485 GD 486
Score = 32.0 bits (71), Expect = 0.43 Identities = 65/306 (21%), Positives = 119/306 (38%), Gaps = 32/306 (10%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 ++QL + H E ++ +E+ K IE D + ++ + + + +E + +R Q Sbjct: 222 QLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIE 281 Query: 65 KCLSDAEEKYSQKEDIY---EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK-L 120 K + + + + +QK Y +E KL+ A+ + ++ K + D+LE + L Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEML 341 Query: 121 KCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSG 180 K +RM ++ +++ Q+ Y +EEA Sbjct: 342 SVEKARQEFEERMEEESQSQGRDLTLEENQVKKYH----------------RLKEEASKR 385 Query: 181 ERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMV 240 T + L N Q RL K ++ K KQ R ++E QK + K E+ I Sbjct: 386 AATLAQELEKFNR-DQKADQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITT 444 Query: 241 ---LAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDA-------GRKKREASL 290 E+ +E L E + R + Q +LGDA R++R+A + Sbjct: 445 SKQSLEEQKKLEGELTEEVEMAK-RRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEI 503 Query: 291 SPETKR 296 KR Sbjct: 504 MESIKR 509
>gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR Length = 2349 Score = 40.8 bits (94), Expect = 0.001 Identities = 64/299 (21%), Positives = 132/299 (44%), Gaps = 55/299 (18%) Query: 2 ELQEIQ-----LKEAKHIAEEADRKYEEVPRKL----VIIEGDLECTEERAELAESRCQE 52 ELQE++ +E + + ++EE+ +K V++E + EE+ L E Q+ Sbjct: 1234 ELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERL-EQDLQQ 1292 Query: 53 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 112 ++R ++ ++ L +A + S+K + + E K+L + +K + R + LV++ +K Sbjct: 1293 MQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKAR---NQHLVSQ-QKD 1348 Query: 113 TDDLEYKLKCNKEENLCTQRMLYQTLLDLNEI------SSVSIQISNYSFRGCCDDQNKG 166 D EY+ K E+ + T+R + Q ++ + S+ S+ + + +D NK Sbjct: 1349 PDTEEYR-KLLSEKEVHTKR-IQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV 1406 Query: 167 RFDGPEAQEEACS------------------GER---TYQELLVNQNPIVQPLA------ 199 R + Q++ + G R Y+EL Q+ +++ A Sbjct: 1407 RTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDH 1466 Query: 200 -----SRRLTRNLYKCIKKA-MKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVL 252 S + + L + + +A K K L V+ +QK +++ E L E T+ ++ L Sbjct: 1467 QEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSEL 1525
Score = 37.4 bits (85), Expect = 0.010 Identities = 51/241 (21%), Positives = 101/241 (41%), Gaps = 30/241 (12%) Query: 35 DLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 94 +LE ++R +S+ T E++ ++L E+ SQ+ + E++K L +KLKE Sbjct: 98 ELEIAQDRNIAIQSQFTRTKEELEAEKRDL---IRTNERLSQELEYLTEDVKRLNEKLKE 154 Query: 95 AETRAEFTERLVAKLEKTTDDLEYKLKCNKEEN--LCTQRMLYQTLL--DLNEISSVSIQ 150 + T + + +L+ + ++Y+ K ++E L +Q T L +E+ ++ + Sbjct: 155 SNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGRE 214 Query: 151 ISNYSFRGCCDDQNKGRFDGPEAQEEACSGERT--------YQELLVNQNPIVQPLASRR 202 N C+ +NK + EE +G +T ++LL + AS Sbjct: 215 KGNEILELKCNLENKK--EEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272 Query: 203 -----------LTRNLYKCI--KKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIE 249 NLYK K +L R V+E+ K + + + + + L +E Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVE 332 Query: 250 E 250 + Sbjct: 333 Q 333
Score = 33.9 bits (76), Expect = 0.11 Identities = 22/97 (22%), Positives = 51/97 (52%), Gaps = 5/97 (5%) Query: 55 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 +Q ++M+ + + D +E++ +++ E L + L +AET+++ E V L+KT Sbjct: 1451 QQDKVMETSAQSSGDHQEQHVSVQEMQE-----LKETLNQAETKSKSLESQVENLQKTLS 1505 Query: 115 DLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQI 151 + E + + +E+ + Q L + DL + ++ Q+ Sbjct: 1506 EKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQL 1542
Score = 33.5 bits (75), Expect = 0.15 Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 13/138 (9%) Query: 17 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD--AEEKY 74 E++++Y E+ ++L ++ER CQ ++ ++ LK L++ E + Sbjct: 49 ESEQQYFEIEKRL-------SHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEI 101 Query: 75 SQKEDIYEEEIKILTDKLKEAETR--AEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 132 +Q +I + T + EAE R ERL +LE T+D++ + KE N T + Sbjct: 102 AQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN--TTK 159 Query: 133 MLYQTLLDLNEISSVSIQ 150 Q LD + S VS++ Sbjct: 160 GELQLKLDELQASDVSVK 177
Score = 30.0 bits (66), Expect = 1.6 Identities = 37/157 (23%), Positives = 64/157 (40%), Gaps = 44/157 (28%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E QL E K EE +R ++ K V RC++ ++Q RL+ + Sbjct: 1121 ESQLLECKASWEERERMLKDEVSKCVC-----------------RCEDLEKQNRLLHDQI 1163 Query: 65 KCLSD------------------AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE--- 103 + LSD +EE SQ++ + E ++ + + + AETR E + Sbjct: 1164 EKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQIL--EILRFIRREKEIAETRFEVAQVES 1221 Query: 104 ----RLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 136 + V LE+ +LE L +E+ T + + Q Sbjct: 1222 LRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQ 1258
Score = 29.3 bits (64), Expect = 2.8 Identities = 33/169 (19%), Positives = 74/169 (43%), Gaps = 21/169 (12%) Query: 48 SRCQETDEQIRLMDQNLKC-----------LSDAEEKYSQKEDIYEEEIKILTDKLKEAE 96 S+ ++T+EQ+ + + LK ++ EE ++++ + EE K + +LKE+ Sbjct: 939 SQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESA 998 Query: 97 TRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE-ISSVSIQISNYS 155 E+ + ++EK +L+ ++ + Q L +L + +SSV ++ Sbjct: 999 EFQTQLEKKLMEVEKEKQELQ-------DDKRRAIESMEQQLSELKKTLSSVQNEVQEAL 1051 Query: 156 FRG--CCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLASRR 202 R ++ + R D E + A + Y+ L+ V+ L + + Sbjct: 1052 QRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAK 1100
Score = 28.5 bits (62), Expect = 4.7 Identities = 25/116 (21%), Positives = 50/116 (43%), Gaps = 4/116 (3%) Query: 32 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 91 I L+ +R E+ + + +I + + + L+ +K Q + ++++ +K Sbjct: 714 ISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEK 773 Query: 92 LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSV 147 L AE RAE ++ L+ + E +L +E L QR L +L I + Sbjct: 774 LAVAEVRAENLKKEKEMLKLS----EVRLSQQRESLLAEQRGQNLLLTNLQTIQGI 825
>gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal muscle, perinatal (MyHC-perinatal) Length = 1937 Score = 40.4 bits (93), Expect = 0.001 Identities = 34/158 (21%), Positives = 68/158 (43%), Gaps = 11/158 (6%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE AEE + E+ K +E EC+E + ++ E T+ Sbjct: 919 EAKIKEVTERAEEEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 976 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K S+++ +E + D L+ E + + KLE+ DD Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISN 153 LE L+ K+ + +R + DL ++ + N Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEN 1074
Score = 40.0 bits (92), Expect = 0.002 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 35/148 (23%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAELAESRCQET 53 LKE + ++A R E++ +L I+E LE TE ++AE + Sbjct: 1653 LKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDA 1712 Query: 54 DEQIRLMD-QNLKCL--------------SDAEEKYSQKEDIYEEEIKILTD------KL 92 E+++L+ QN + S+ EE + + E+ K +TD +L Sbjct: 1713 SERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL 1772 Query: 93 KEAETRAEFTERLVAKLEKTTDDLEYKL 120 K+ + + ER+ LE+T DL+++L Sbjct: 1773 KKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Score = 34.7 bits (78), Expect = 0.066 Identities = 28/117 (23%), Positives = 52/117 (44%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ DE++ + + Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L E E +++IK L +++E E AK EK DL +L+ Sbjct: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Score = 33.5 bits (75), Expect = 0.15 Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 1/116 (0%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL-K 65 Q++E KH EE + + L D + E+ E + E + + + + Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373 Query: 66 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + E Q+ + EE K L +L+EAE E A LEKT L+ +++ Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
Score = 31.2 bits (69), Expect = 0.73 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 22/136 (16%) Query: 7 QLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQETDEQIR 58 +L EA+ +A + +K +++ ++ +EG++E ++R A E R +E Q Sbjct: 1799 RLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTE 1858 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFTER 104 +N+ L D +K K Y+ + + L +L+EAE RA+ E Sbjct: 1859 EDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAES 1918 Query: 105 LVAKLEKTTDDLEYKL 120 V KL + ++ K+ Sbjct: 1919 QVNKLRVKSREVHTKI 1934
Score = 30.0 bits (66), Expect = 1.6 Identities = 31/136 (22%), Positives = 63/136 (46%), Gaps = 13/136 (9%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVII-----EGDLECTEERAELA--ESRCQET 53 M + + ++ K +++ K +E+ K+V + + L+ E LA E RC++ Sbjct: 852 MATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQL 911 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLE 110 + ++ +K + E+ ++E+I E + + L D+ E + + E +AK+E Sbjct: 912 IKNKIQLEAKIK---EVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968 Query: 111 KTTDDLEYKLKCNKEE 126 K E K+K EE Sbjct: 969 KEKHATENKVKNLTEE 984
Score = 29.3 bits (64), Expect = 2.8 Identities = 16/45 (35%), Positives = 27/45 (60%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 49 + ++K K AEEA+ + K ++ +LE EERA++AES+ Sbjct: 1875 QAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQ 1919
>gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skeletal muscle, extraocular (MyHC-eo) Length = 1938 Score = 40.0 bits (92), Expect = 0.002 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS---DAEEKYSQKED 79 E RKL EGDL+ ++E E+ Q+ +E+++ + L L D E+ +S + Sbjct: 1053 ERAKRKL---EGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQ-- 1107 Query: 80 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++++IK L +++E E E L AK+EK DL +L+ Sbjct: 1108 -FQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELE 1148
Score = 40.0 bits (92), Expect = 0.002 Identities = 29/124 (23%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 EL E +L+E + + E K + K ++ D++ E E T+ +++ + Sbjct: 925 ELTE-RLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLS 983 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + + L + K ++++ +E + D L+ E + ++ AKLE+ TDDLE L+ Sbjct: 984 EEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLE 1043 Query: 122 CNKE 125 K+ Sbjct: 1044 QEKK 1047
Score = 39.3 bits (90), Expect = 0.003 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 35/149 (23%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEG--------------DLECTEERAELAESRCQE 52 QLK+++ ++A R E++ +L I+E LE TE L+E + Sbjct: 1653 QLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLD 1712 Query: 53 TDEQIRLM-DQN--------------LKCLSDAEEKYSQKEDIYEEEIKILTD------K 91 ++++L+ QN +C ++ E + + E+ K +TD + Sbjct: 1713 ASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEE 1772 Query: 92 LKEAETRAEFTERLVAKLEKTTDDLEYKL 120 LK+ + + ER+ LE+T DL+++L Sbjct: 1773 LKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Score = 39.3 bits (90), Expect = 0.003 Identities = 57/258 (22%), Positives = 117/258 (45%), Gaps = 44/258 (17%) Query: 21 KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI--RLMDQN---------LKCLSD 69 K E +++ ++ D E T+E +E+R +E +E++ L ++N + L D Sbjct: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904 Query: 70 AEEKYS---QKEDIYEEEIKILTDKLKEAETRAEFTERLVAK----------LEKTTDDL 116 AEE+ + + + E ++K LT++L+E E E LVAK L++ DDL Sbjct: 905 AEERCEGLIKSKILLEAKVKELTERLEEEE---EMNSELVAKKRNLEDKCSSLKRDIDDL 961 Query: 117 EYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYS-FRGCCDDQNKGRFDGPEAQE 175 E L ++E T+ + E++++ IS + + + ++ D + +E Sbjct: 962 ELTLTKVEKEKHATENKVKNL---SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018 Query: 176 EACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMK-QKQLRRGVKEVQKFVNKG 234 + +G L+ N ++ + T +L +++ K + L R ++++ + Sbjct: 1019 DKVNG-------LIKINAKLE-----QQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMS 1066 Query: 235 EKGIMVLAEDTLPIEEVL 252 ++ IM L + IEE L Sbjct: 1067 QESIMDLENEKQQIEEKL 1084
Score = 33.9 bits (76), Expect = 0.11 Identities = 60/264 (22%), Positives = 101/264 (38%), Gaps = 52/264 (19%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E L E + ++R+ E R L ++G L+ D Q+ L D L Sbjct: 1623 EGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLK----------------DSQLHL-DDAL 1665 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 + D +E+ + I E +L ++L+E + E TER E+ D +++ Sbjct: 1666 RSNEDLKEQLA----IVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLH 1721 Query: 125 EEN---LCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGE 181 +N + T++ L + SIQ S R + K D EE + Sbjct: 1722 SQNTSLINTKKKLEADIAQCQAEVENSIQES----RNAEEKAKKAITDAAMMAEELKKEQ 1777 Query: 182 RTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAM------KQKQLRRGVKEVQKFVNKGE 235 T L R+ +NL + +K +Q L+ G K++QK N+ Sbjct: 1778 DTSAHL-------------ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVR 1824 Query: 236 KGIMVLAEDTLPIEEVLGPEALFG 259 + E+ L +E+ G EAL G Sbjct: 1825 E-----LENELDVEQKRGAEALKG 1843
Score = 32.3 bits (72), Expect = 0.33 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QL+E K EE + + L D + E+ E E + + + Q L N + Sbjct: 1315 QLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE- 1371 Query: 67 LSDAEEKYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 ++ + KY Q+ + EE K L +L+EAE + E A LEKT L+ Sbjct: 1372 VAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQ 1426
Score = 28.5 bits (62), Expect = 4.7 Identities = 23/128 (17%), Positives = 55/128 (42%) Query: 19 DRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKE 78 D+K + L + L+ ++ E A+ + ++ M + + D E ++ Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506 Query: 79 DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTL 138 +EEI LT+++ E + E+ +E+ DL+ L+ + + + + Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566 Query: 139 LDLNEISS 146 L+L+++ S Sbjct: 1567 LELSQVKS 1574
Score = 28.5 bits (62), Expect = 4.7 Identities = 26/123 (21%), Positives = 54/123 (43%), Gaps = 2/123 (1%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 +E+ EA+ +E + K + ++ ++ ++ E AE RC+ + L++ Sbjct: 865 EELARSEARR--KELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAK 922 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 +K L++ E+ + + + L DK + + E + K+EK E K+K Sbjct: 923 VKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNL 982 Query: 124 KEE 126 EE Sbjct: 983 SEE 985
>gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 Length = 354 Score = 40.0 bits (92), Expect = 0.002 Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 19/129 (14%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 EEA+R ++ V +LEC +A + E ++ I+ +++ LK + E+ Sbjct: 220 EEAERLHKRVT--------ELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271 Query: 76 QKED---IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 132 Q+ D +E+ LT KL+E E R + LE DLE +L+ ++ E + Sbjct: 272 QEIDNARELQEQRDSLTQKLQEVEIRNK-------DLEGQLSDLEQRLEKSQNEQEAFRN 324 Query: 133 MLYQTLLDL 141 L +TLL++ Sbjct: 325 NL-KTLLEI 332
>gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmuscle type A (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 40.0 bits (92), Expect = 0.002 Identities = 60/262 (22%), Positives = 105/262 (40%), Gaps = 53/262 (20%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLE--C--TEERAELAESRCQETDEQIRL 59 +++QL+E E + EE+ +L + +LE C E R E E RCQ + + Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940 Query: 60 MDQNLK-----------------------------------CLSDAEEKYSQKEDIYEEE 84 M QN++ L D K ++++ + E+ Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR 1000 Query: 85 IKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK---CNKEENLCTQRMLYQTLLDL 141 I T L E E +++ +L K E DLE +L+ ++E T+R L DL Sbjct: 1001 IAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDL 1060 Query: 142 -NEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGE---RTYQELLVNQNPIVQP 197 ++I+ + QI+ + + + + +EEA + +EL + + + Sbjct: 1061 SDQIAELQAQIAELKMQ-LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119 Query: 198 LASRRLTRNLYKCIKKAMKQKQ 219 L S R +RN KA KQK+ Sbjct: 1120 LESERASRN------KAEKQKR 1135
Score = 31.2 bits (69), Expect = 0.73 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 7/116 (6%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 ELQE L+ + +A+++ ++ +L ++ +LE T + + + ++++ ++ Sbjct: 1115 ELQE-DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 + L+ EE + + I E K + ++E + E T+R+ A LEK LE Sbjct: 1174 KTLE-----EEAKTHEAQIQEMRQKH-SQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 30.0 bits (66), Expect = 1.6 Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 22/137 (16%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEER---------AELAESRCQ 51 + L+ ++ ++ ++ +R+ +E+ KL +EG ++ + A+L E Sbjct: 1766 LNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDN 1825 Query: 52 ETDE------QIRLMDQNLKCLS---DAE----EKYSQKEDIYEEEIKILTDKLKEAETR 98 ET E Q+R ++ LK + D E E+Y + D +K L +L+EAE Sbjct: 1826 ETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE 1885 Query: 99 AEFTERLVAKLEKTTDD 115 A+ KL++ +D Sbjct: 1886 AQRANASRRKLQRELED 1902
>gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium specific protein 1 Length = 386 Score = 40.0 bits (92), Expect = 0.002 Identities = 40/154 (25%), Positives = 78/154 (50%), Gaps = 17/154 (11%) Query: 2 ELQEIQLKEAKHIAEEADRKYEE--VPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 ++ E++ +++ EE +RK E + + I+E + EER+ LAE R QE ++ + Sbjct: 92 QMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEY 151 Query: 60 MDQ-NLKCLSDAEEKYSQKEDIYEEEIKILTD--KLKEAETRA----------EFTERLV 106 M+Q + L D E + QK + + EIK + D + ++AE A EFT++ + Sbjct: 152 MEQLQEEDLKDMERRQQQKLKM-QAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKM 210 Query: 107 AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 140 A+ E + + +++ KE+ + R + + D Sbjct: 211 AR-EAEFEAEQERIRREKEKEIARLRAMQEKAQD 243
>gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 Length = 957 Score = 39.7 bits (91), Expect = 0.002 Identities = 56/248 (22%), Positives = 101/248 (40%), Gaps = 19/248 (7%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAE-LAESRCQETDEQIRL 59 MEL+ K+ + +E+ +K E+ + + LE ER +AE+ Q + ++ + Sbjct: 287 MELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEV-I 345 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 +DQ K E+ ++ + E K K +T E + +A LE+ DLE + Sbjct: 346 LDQKEKENIHLREELHRRSQLQPEPAKT-----KALQTVIEMKDTKIASLERNIRDLEDE 400 Query: 120 LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACS 179 ++ K + + EI + + S+ F DQ K E++ A Sbjct: 401 IQMLKANGVLNTEDREE------EIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLAL- 453 Query: 180 GERTYQELLVNQNPIVQ---PLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEK 236 +T E L NQN + + LT + + LR ++E + F+NK K Sbjct: 454 --QTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511 Query: 237 GIMVLAED 244 + L E+ Sbjct: 512 QLQDLTEE 519
Score = 29.3 bits (64), Expect = 2.8 Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 10/139 (7%) Query: 4 QEIQLKEAKHIAEEADRKYEEVP---RKLVIIE--GDLECTEERAELAESRCQETDEQIR 58 Q+++ K+ + EE R+ + + + L I E LE T + + ++R T + + Sbjct: 772 QQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA 831 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 + +L L E+ Q E+I E + + L + E + E +K +KT +++ Sbjct: 832 EKEAHLANLRI--ERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEV-- 887 Query: 119 KLKCNKEENLCTQRMLYQT 137 + +E++ ++ QT Sbjct: 888 -MALKREKDRLVHQLKQQT 905
>gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE) Length = 1940 Score = 39.7 bits (91), Expect = 0.002 Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 35/149 (23%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAELAESRCQE 52 QLK+ + ++A R E++ +L I+E LE TE +LAE + Sbjct: 1650 QLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 1709 Query: 53 TDEQIRLM-DQN--------------LKCLSDAEEKYSQKEDIYEEEIKILTD------K 91 ++E+++L+ QN ++ S+ E+ + E+ K +TD + Sbjct: 1710 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 1769 Query: 92 LKEAETRAEFTERLVAKLEKTTDDLEYKL 120 LK+ + + ER+ LE+T DL+++L Sbjct: 1770 LKKEQDTSAHLERMKKNLEQTVKDLQHRL 1798
Score = 38.1 bits (87), Expect = 0.006 Identities = 35/175 (20%), Positives = 76/175 (43%), Gaps = 22/175 (12%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 917 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 974 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + L L + K ++++ +E + D L+ E + + +KLE+ +D Sbjct: 975 KVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVED 1034 Query: 116 LEYKLKCNKEENLCTQR----------MLYQTLLDL-NEISSVSIQISNYSFRGC 159 LE L+ K+ + +R + +++LDL N+ + ++ F C Sbjct: 1035 LESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYC 1089
Score = 33.5 bits (75), Expect = 0.15 Identities = 20/68 (29%), Positives = 36/68 (52%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 ++++K K AEEAD + K + +LE EERA++AES+ + + R + Sbjct: 1873 QVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932 Query: 65 KCLSDAEE 72 + ++EE Sbjct: 1933 MVVHESEE 1940
Score = 29.3 bits (64), Expect = 2.8 Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 13/136 (9%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLE----CTEERAELAESRCQET 53 M + + ++ K +++ K +E+ KLV + + DL+ E AE RC + Sbjct: 850 MATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQL 909 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLE 110 + ++ +K + E+ +E+I E + + L D+ E + + E +AK+E Sbjct: 910 IKAKFQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 966 Query: 111 KTTDDLEYKLKCNKEE 126 K E K+K EE Sbjct: 967 KEKHATENKVKNLTEE 982
Score = 28.9 bits (63), Expect = 3.6 Identities = 26/141 (18%), Positives = 62/141 (43%), Gaps = 21/141 (14%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q+++ + E+ + ++ R +EGDL+ +E E+ Q+ DE+++ D Sbjct: 1029 EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDF-- 1086 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 +Y Q L K+++ +T ++ + +L+ ++LE +++ + Sbjct: 1087 --------EYCQ-----------LQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127 Query: 125 EENLCTQRMLYQTLLDLNEIS 145 T++ +L E+S Sbjct: 1128 ATRAKTEKQRSDYARELEELS 1148
>gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) Length = 1116 Score = 39.7 bits (91), Expect = 0.002 Identities = 29/142 (20%), Positives = 67/142 (47%), Gaps = 4/142 (2%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVP--RKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 L E + KE + EE R++E P K ++ +E + + E ++ +E+I+++ Sbjct: 349 LLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQML 408 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 N ++ E+ ++ ++Y K + +K+++ + E +L+K L+ ++ Sbjct: 409 KSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEI 468 Query: 121 KCNKEE--NLCTQRMLYQTLLD 140 K+E T+ + QT L+ Sbjct: 469 GQVKQELSRKDTELLALQTKLE 490
Score = 30.0 bits (66), Expect = 1.6 Identities = 25/138 (18%), Positives = 62/138 (44%), Gaps = 11/138 (7%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK-- 65 LKE ++ + D+K E+ R++ + + + ++ + + + E+ R + NL Sbjct: 765 LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDS 824 Query: 66 ------CLSDAEEKYSQKEDIYEEEIKILTDK---LKEAETRAEFTERLVAKLEKTTDDL 116 L +++ + E+ E ++I ++ L + E+ E+ V +L + + Sbjct: 825 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 884 Query: 117 EYKLKCNKEENLCTQRML 134 + +L+ K + TQ+ L Sbjct: 885 KQELESMKAKLSSTQQSL 902
>gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin subfamily B member 1 (Giantin) (Macrogolgin) (Golgi complex-associated protein, 372-kDa) (GCP372) Length = 3259 Score = 38.9 bits (89), Expect = 0.003 Identities = 68/317 (21%), Positives = 131/317 (41%), Gaps = 38/317 (11%) Query: 6 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 65 +QL + E +K + RKL E L + +L + +++ +++ Q L+ Sbjct: 238 LQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQ 297 Query: 66 CLSDAEEKYSQKEDIYEEEIKILTDK--LKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 + + EE KIL +K L+ AE + F L ++ + E + Sbjct: 298 QMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSF-HNLQEEMHHLLEQFEQAGQAQ 356 Query: 124 KEENLCTQRMLYQTLLDLNEISS--VSIQISNYSFRGCCD---DQNKGRFDGPEAQEEAC 178 E + + ++ E +S +S+Q + + CD DQN + E+A Sbjct: 357 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQ--DKNEQAV 414 Query: 179 SGERTYQEL-------------LVNQNPIVQ-PLASRRLTRNLYKCIKKAMKQKQLRRGV 224 +T Q+L +N+ P+ Q AS+ ++Y +A+ ++ + Sbjct: 415 QSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQ 474 Query: 225 KEVQKFVNKGEKGIMVLAEDTLPIEEVLGP-EALFGRVRWRPGAAQTAPQEPSKLGDAGR 283 K V + N EKG ++L+ ++ +EE+ E L ++ T + ++ G+A R Sbjct: 475 KRVVELEN--EKGALLLS--SIELEELKAENEKLSSQI--------TLLEAQNRTGEADR 522 Query: 284 KKREASL-SPETKRSSS 299 + E S+ KRSSS Sbjct: 523 EVSEISIVDIANKRSSS 539
Score = 37.4 bits (85), Expect = 0.010 Identities = 44/214 (20%), Positives = 90/214 (42%), Gaps = 23/214 (10%) Query: 9 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 68 K + ++ DR +E + ++ EE L E C +Q+R M +++ L Sbjct: 2192 KSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELK 2251 Query: 69 DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 128 + + I+E +A+T + +++ L+ +L +L+ + Sbjct: 2252 INISRLEHDKQIWE----------SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYH 2301 Query: 129 CTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEA--CSGERTYQE 186 +Q L + +L + +SN S C + KG +G Q+EA + + +Y++ Sbjct: 2302 SSQNELAKLESELKSLKDQLTDLSN-SLEKC--KEQKGNLEGIIRQQEADIQNSKFSYEQ 2358 Query: 187 LLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQL 220 L + ASR LT L++ I MK++++ Sbjct: 2359 LETDLQ------ASRELTSRLHEEIN--MKEQKI 2384
Score = 32.0 bits (71), Expect = 0.43 Identities = 30/144 (20%), Positives = 65/144 (45%), Gaps = 14/144 (9%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 + + +H+ E ++ +E+ KL E + + TE++ + AE +E E++R Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF------ 1681 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 A+ K + ++ EE ++ + +T E E L++ ++LE ++K E Sbjct: 1682 ---AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELE-RVKMEYE- 1736 Query: 127 NLCTQRMLYQTLLDLNEISSVSIQ 150 T +Q+L+ + S +Q Sbjct: 1737 ---TLSKKFQSLMSEKDSLSEEVQ 1757
Score = 28.1 bits (61), Expect = 6.2 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 11/90 (12%) Query: 35 DLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 94 D E + R +L + + +Q +L++ L+ + E KY++ E+ KLKE Sbjct: 2530 DAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEE-----------KLKE 2578 Query: 95 AETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 +E E R L++ DL +++ K Sbjct: 2579 SEEANEDLRRSFNALQEEKQDLSKEIESLK 2608
Score = 28.1 bits (61), Expect = 6.2 Identities = 13/75 (17%), Positives = 40/75 (53%) Query: 47 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV 106 + + +E ++ ++ Q+ + +S+ E+ + +E + L KL+ E + TE+ + Sbjct: 1605 QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL 1664 Query: 107 AKLEKTTDDLEYKLK 121 + E+ ++++ K++ Sbjct: 1665 QEAEQEMEEMKEKMR 1679
>gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-activating modulator Length = 531 Score = 38.5 bits (88), Expect = 0.005 Identities = 27/127 (21%), Positives = 61/127 (48%), Gaps = 9/127 (7%) Query: 6 IQLKEAKHIAEE-ADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 +++++ K+ E+ A ++V + + E L+ T+ LAE +C+E Q + ++ Sbjct: 250 LEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDW 309 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC-N 123 + L + E ++ +L KL+ A++R + + LE L+ K++C Sbjct: 310 RTLGTQHRE-------LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQ 362 Query: 124 KEENLCT 130 + +LC+ Sbjct: 363 GDRDLCS 369
>gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen) Length = 2115 Score = 38.5 bits (88), Expect = 0.005 Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 15/146 (10%) Query: 4 QEIQL-KEAKHIAE----EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR 58 Q++Q+ EA+ A+ +A R+ E+ RK+ ++ +E + A+++ E + Q+R Sbjct: 622 QQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 681 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 Q + +E+ +Q++D +E+++ L + LK + E +R + D LE Sbjct: 682 SEQQK----ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKR------RAADALEE 731 Query: 119 KLKCNKEENLCTQRMLYQTLLDLNEI 144 + +C E T+ ++ Q + E+ Sbjct: 732 QQRCISELKAETRSLVEQHKRERKEL 757
Score = 30.4 bits (67), Expect = 1.2 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 4/123 (3%) Query: 26 PRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEI 85 P++L + E R +CQ+ + MD+ + LS+ S K + + Sbjct: 275 PKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHL 334 Query: 86 KILTDKLKE-AETRAEFTERLV---AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 + L D L E E ++ T+ + A+LEK KC +E+N Q L Q L Sbjct: 335 QQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHL 394 Query: 142 NEI 144 +++ Sbjct: 395 SQL 397
Score = 28.9 bits (63), Expect = 3.6 Identities = 24/127 (18%), Positives = 64/127 (50%), Gaps = 7/127 (5%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 Q+++ + E ++ EE+ +KL + + +++ + +++ E+ ++ + + Sbjct: 1536 QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQ--- 1592 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 L++ + + SQKE E K+ ++++A+T + ++ +L++ LE K NKE Sbjct: 1593 LNELQAQLSQKEQA-AEHYKL---QMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1648 Query: 127 NLCTQRM 133 +R+ Sbjct: 1649 RAEAERL 1655
>gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin Length = 1898 Score = 38.5 bits (88), Expect = 0.005 Identities = 36/145 (24%), Positives = 68/145 (46%), Gaps = 18/145 (12%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE---RAELAESRCQETDEQIRLM 60 +++Q KE + + EE +++ + K E +L+ EE R E + R QE + Q R Sbjct: 981 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1040 Query: 61 DQ-------------NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVA 107 D+ + L + E +Y ++E++ +EE ++L ++ +E R E ER Sbjct: 1041 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE-RETRRRQEL-ERQYR 1098 Query: 108 KLEKTTDDLEYKLKCNKEENLCTQR 132 K E+ + E L+ E+ +R Sbjct: 1099 KEEELQQEEEQLLREEPEKRRRQER 1123
Score = 37.4 bits (85), Expect = 0.010 Identities = 30/129 (23%), Positives = 63/129 (48%), Gaps = 8/129 (6%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 QE Q +E + + +E ++ E K E ER + + Q+ +EQ+ + Sbjct: 943 QERQYREEEQLQQEEEQLLREEREKRRRQE------RERQYRKDKKLQQKEEQLLGEEPE 996 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 + + E+KY ++E++ +EE ++L ++ +E R E+ ER K ++ + E L+ Sbjct: 997 KRRRQEREKKYREEEELQQEEEQLLREE-REKRRRQEW-ERQYRKKDELQQEEEQLLREE 1054 Query: 124 KEENLCTQR 132 +E+ +R Sbjct: 1055 REKRRLQER 1063
Score = 34.3 bits (77), Expect = 0.086 Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 5/125 (4%) Query: 14 IAEEADRKYEEVPRKLVIIEGDLECTE--ERAELAESRCQETDEQIRLMDQNLKCLSDAE 71 + +E ++ EE P++ ++ + E ER EL R +E +Q RL + E Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312 Query: 72 EKYSQKEDIYE-EEIKILTDKLKEAETRAEFTERLVAKL--EKTTDDLEYKLKCNKEENL 128 E+ Q+E+ E +E + ++ +E + R E ER +L E+ + E +L+ +EE Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372 Query: 129 CTQRM 133 Q++ Sbjct: 373 REQQL 377
Score = 33.5 bits (75), Expect = 0.15 Identities = 36/133 (27%), Positives = 62/133 (46%), Gaps = 11/133 (8%) Query: 4 QEIQLKEAKHIAEEADR----KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 QE + ++ K EE R K EE R+ + + E+ E E R + +E+ RL Sbjct: 488 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 547 Query: 60 MDQNLKCLSDAEEKYSQKEDIYE----EEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 Q L+ S+ + + Q+E + + EE K L + +E + E ER L++ + Sbjct: 548 Q-QRLR--SEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 604 Query: 116 LEYKLKCNKEENL 128 + +LK +EE L Sbjct: 605 RQQRLKREQEERL 617
Score = 33.1 bits (74), Expect = 0.19 Identities = 68/308 (22%), Positives = 132/308 (42%), Gaps = 36/308 (11%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR--CQETDE-QIRLM 60 ++ +L+E K +E +RK+ E ++L EG + +E + E QE +E Q+ Sbjct: 1535 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQEDRKFREDEQLLQEREEQQLHRQ 1594 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTD-KLKEAETRAEFTERLVAKLEKTTDDLEYK 119 +++ K L EE+ + E++++ D K +E E + E +L + D +++ Sbjct: 1595 ERDRKFL---EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEE--QQLRRQERDRKFR 1649 Query: 120 LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACS 179 +E+ L Q + L + ++ ++ FR ++Q + E ++E Sbjct: 1650 ---EEEQQLRRQERERKFLQEEQQLRRQELE---RKFRE--EEQLR-----QETEQEQLR 1696 Query: 180 GERTYQELLVNQ--NPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKG 237 + Y+++L + P + RR R+ +K +++QLR+G +E Q + E Sbjct: 1697 RQERYRKILEEEQLRPEREEQQLRRQERD-----RKFREEEQLRQGREEQQ--LRSQESD 1749 Query: 238 IMVLAEDTL---PIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKR--EASLSP 292 E+ L E+ L P+ G+ RW Q QE + R+ R E + Sbjct: 1750 RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQ 1809 Query: 293 ETKRSSSQ 300 E R Q Sbjct: 1810 EKSRREEQ 1817
Score = 32.3 bits (72), Expect = 0.33 Identities = 24/123 (19%), Positives = 56/123 (45%), Gaps = 11/123 (8%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q ++ + + +E ++ E P K E + +C E E Q+ +EQ+ ++ Sbjct: 1094 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE------EEELQQEEEQLLREEREK 1147 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 + + E +Y ++E++ ++ K + ++ + R++ + + E D K+ C Sbjct: 1148 RRRQELERQYREEEELQRQKRK---QRYRDEDQRSDLKWQWEPEKENAVRD--NKVYCKG 1202 Query: 125 EEN 127 EN Sbjct: 1203 REN 1205
Score = 30.0 bits (66), Expect = 1.6 Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 9/107 (8%) Query: 2 ELQEIQLKEAKHIAEEADRKY---EEVPRKLVIIEGDLECTEERAELA-----ESRCQET 53 E Q ++ + K +E +R+Y EE+ ++ + G+ T R EL E Q+ Sbjct: 1047 EEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQE 1106 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 +EQ+ + + + E + ++E++ +EE ++L ++ +E R E Sbjct: 1107 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE-REKRRRQE 1152
Score = 29.6 bits (65), Expect = 2.1 Identities = 26/129 (20%), Positives = 59/129 (45%), Gaps = 4/129 (3%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E Q+ + + + +E + K E ++ ++ + E +E + QE +EQ+R ++ Sbjct: 225 EKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEI--KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 + EE+ Q+ E+++ K ++ ++ E R E ER + E+ L + Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342 Query: 120 LKCNKEENL 128 + +E+ L Sbjct: 343 QEERREQQL 351
>gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein) Length = 1235 Score = 38.5 bits (88), Expect = 0.005 Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 13/128 (10%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +EL+ QL K + E+ +K + ++L ++ + + EER + R E + Sbjct: 365 IELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGE-------V 417 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 NLK + + E + ++ + EE K D LKE + + E LV ++EKT + Sbjct: 418 QGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQ---EETLVDEIEKTKSRMS--- 471 Query: 121 KCNKEENL 128 + N+E NL Sbjct: 472 EFNEELNL 479
>gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skeletal muscle, adult 1 (Myosin heavy chain IIx/d) (MyHC-IIx/d) Length = 1939 Score = 38.1 bits (87), Expect = 0.006 Identities = 33/158 (20%), Positives = 68/158 (43%), Gaps = 11/158 (6%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 977 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1037 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISN 153 LE L+ K+ + +R + DL ++ I N Sbjct: 1038 LEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIEN 1075
Score = 37.4 bits (85), Expect = 0.010 Identities = 37/172 (21%), Positives = 68/172 (39%), Gaps = 56/172 (32%) Query: 5 EIQLKEAKHIAEEADRKY---------------------EEVPRKLVIIE---------- 33 EIQL A +A EA R Y E++ +L ++E Sbjct: 1630 EIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEI 1689 Query: 34 ----GDLECTEERAELAESRCQETDEQIRLM--------DQNLKCLSDAEEKYSQKEDIY 81 LE TE ++AE + E+++L+ + K +D + + EDI Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749 Query: 82 EE-------------EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 +E + ++ ++LK+ + + ER+ LE+T DL+++L Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Score = 37.4 bits (85), Expect = 0.010 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 3/99 (3%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 82 E RKL EGDL+ +E A E+ Q+ DE+++ + + L E + Sbjct: 1053 ERAKRKL---EGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQ 1109 Query: 83 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++IK L +++E E E AK EK DL +L+ Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Score = 35.0 bits (79), Expect = 0.050 Identities = 56/256 (21%), Positives = 99/256 (38%), Gaps = 54/256 (21%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI----RLMDQNLKCLSDAE 71 EE R+ EE + + L+ + +L + +E E R M + ++ Sbjct: 1317 EELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR 1376 Query: 72 EKYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEEN 127 KY Q+ + EE K L +L++AE E A LEKT L+ Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQ---------- 1426 Query: 128 LCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQ-EEACSGERTYQE 186 NE+ + I + + D+ + FD A+ ++ C E T+ E Sbjct: 1427 --------------NEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKC--EETHAE 1470 Query: 187 LLVNQNPIVQPLASRRLTRNLYKCIKKAMKQ------------KQLRRGVKEVQKFVNKG 234 L +Q SR L+ L+K IK A ++ K L++ + ++ + + +G Sbjct: 1471 LEASQK------ESRSLSTELFK-IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1523 Query: 235 EKGIMVLAEDTLPIEE 250 K I L + +E+ Sbjct: 1524 GKRIHELEKIKKQVEQ 1539
Score = 32.3 bits (72), Expect = 0.33 Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 10/123 (8%) Query: 30 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEE------ 83 ++ E +C E AEL S+ E L + K + EE Q E + E Sbjct: 1456 ILAEWKQKCEETHAELEASQ----KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511 Query: 84 EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE 143 EI LT+++ E R E++ ++E+ +L+ L+ + + + + L+LN+ Sbjct: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571 Query: 144 ISS 146 + S Sbjct: 1572 VKS 1574
Score = 30.0 bits (66), Expect = 1.6 Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 + ++K K AEEA+ + K I+ +LE EERA++AES+ + +++ + + Sbjct: 1876 QAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKL--RVKSREVHT 1933 Query: 65 KCLSD 69 K +S+ Sbjct: 1934 KIISE 1938
Score = 30.0 bits (66), Expect = 1.6 Identities = 30/136 (22%), Positives = 61/136 (44%), Gaps = 22/136 (16%) Query: 7 QLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQETDEQIR 58 +L EA+ +A + +K +++ ++ +EG++E ++R A E + +E Q Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTE 1859 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFTER 104 +N+ L D +K K Y+ + + + +L+EAE RA+ E Sbjct: 1860 EDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAES 1919 Query: 105 LVAKLEKTTDDLEYKL 120 V KL + ++ K+ Sbjct: 1920 QVNKLRVKSREVHTKI 1935
Score = 29.6 bits (65), Expect = 2.1 Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD--LECTEERAELAESRCQETDEQIRLMD 61 +E + ++ + EEA ++E L D E E+ L + Q+ +++ M Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK-QKLEKEKSEMK 1229 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL-----EKTTDDL 116 + L+ E S+ + E+ + L D+L E +T+ E +RL+ L T+ Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG 1289 Query: 117 EYKLKCNKEENLCTQ 131 EY + ++++ L +Q Sbjct: 1290 EYSRQLDEKDTLVSQ 1304
Score = 28.5 bits (62), Expect = 4.7 Identities = 25/144 (17%), Positives = 68/144 (47%), Gaps = 4/144 (2%) Query: 3 LQEIQLKEAK-HIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 L ++Q +E K + +A K E+ ++ +EG LE ++ E ++ + ++L Sbjct: 1011 LDDLQAEEDKVNTLTKAKIKLEQ---QVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++ + + +++ +K E E+ L K+++ + ++ + +L+ ++LE +++ Sbjct: 1068 ESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127 Query: 122 CNKEENLCTQRMLYQTLLDLNEIS 145 + ++ +L EIS Sbjct: 1128 AERASRAKAEKQRSDLSRELEEIS 1151
Score = 27.7 bits (60), Expect = 8.1 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 15/131 (11%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQETDEQIR 58 + ++ K + + K +E+ K+V + + DL+ + +AE AE RC + + Sbjct: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADSLADAEERCDQLIKTKI 917 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 ++ +K + E+ +E+I E + + L D+ E + + E +AK+EK Sbjct: 918 QLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 974 Query: 116 LEYKLKCNKEE 126 E K+K EE Sbjct: 975 TENKVKNLTEE 985
>gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8 (230 kDa bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) Length = 3214 Score = 38.1 bits (87), Expect = 0.006 Identities = 37/186 (19%), Positives = 83/186 (44%), Gaps = 10/186 (5%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 Q+ E +A++ E+ +L ++ + +EE+A L + + ET+ +R C Sbjct: 1932 QVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLR-------C 1984 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 L E+ Q E Y ++++ L +L + +AE + + L+K + + +L+ E Sbjct: 1985 LKLELERKDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHE 2044 Query: 127 NLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSG--ERTY 184 QR + + + ++ +IQ N D++ R + + + E+++ Sbjct: 2045 KGKLQREV-DRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSH 2103 Query: 185 QELLVN 190 ++LL N Sbjct: 2104 EQLLQN 2109
Score = 32.7 bits (73), Expect = 0.25 Identities = 29/134 (21%), Positives = 63/134 (47%), Gaps = 14/134 (10%) Query: 7 QLKEAKHIAEEADRKYEEVPR-----KLVI--IEGDLECTEERAELAESRCQETDEQIRL 59 +L+++ AE +K EE+ R KL++ I+ + E + + RC+ Q Sbjct: 2126 ELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADG 2185 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR-AEFTER------LVAKLEKT 112 L+ ++ K ++ E ++ +IK L + L +++ +EF ++ ++ +K Sbjct: 2186 FKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKE 2245 Query: 113 TDDLEYKLKCNKEE 126 +L +L +KEE Sbjct: 2246 VRNLNAELNASKEE 2259
Score = 32.3 bits (72), Expect = 0.33 Identities = 25/154 (16%), Positives = 67/154 (43%), Gaps = 11/154 (7%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRC-------QETDEQIRL 59 QL+ + + ++ RK+ +E DL ++ + +C Q T +++R Sbjct: 2189 QLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRN 2248 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE---FTERLVAKLEKTTDDL 116 ++ L + + + QK + + +++ L ++LK+ + E++ + + Sbjct: 2249 LNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEE 2308 Query: 117 EYKLKCNKEE-NLCTQRMLYQTLLDLNEISSVSI 149 K K + EE ++++ ++ N+IS + + Sbjct: 2309 SGKFKQSAEEFRKKMEKLMESKVITENDISGIRL 2342
>gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein (CDP) (Cut-like 1) Length = 1505 Score = 37.7 bits (86), Expect = 0.008 Identities = 35/123 (28%), Positives = 56/123 (45%), Gaps = 11/123 (8%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 EE K +E+ +I DLE +RAE+A+ + EQ+ + +L+ S Sbjct: 220 EETTAKADEIE----MIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQI----- 270 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLY 135 QK E+ I++LT E E A+ ER +A+L + L+ L +E + L Sbjct: 271 QKAPDVEQAIEVLTRSSLEVELAAK--EREIAQLVEDVQRLQASLTKLRENSASQISQLE 328 Query: 136 QTL 138 Q L Sbjct: 329 QQL 331
Score = 31.6 bits (70), Expect = 0.56 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 10/124 (8%) Query: 2 ELQEIQLKEAKHIAEEADRK----YEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI 57 E ++ +A+ IA E ++K + E RKL + E AE Q E+ Sbjct: 148 EYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKT 207 Query: 58 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 R L D + KY ++ +EI+++ L+ A RAE +R L + Sbjct: 208 RTE------LFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSAN 261 Query: 118 YKLK 121 + L+ Sbjct: 262 HSLQ 265
>gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D) Length = 2025 Score = 37.7 bits (86), Expect = 0.008 Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 67 L+E + + E+ R EE ++ L+ E + + +E E+++ + + +K + Sbjct: 1521 LEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKV 1580 Query: 68 SDAEEKYSQKEDIYEEEIKI-LTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 S+A E Y+QK D E+E ++ L L+ + T ++ ++K +D E Sbjct: 1581 SNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYE 1631
Score = 30.0 bits (66), Expect = 1.6 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Query: 82 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 E+E ++L D+L+E E E++ K + T DLE KLK + EEN ++ L L DL Sbjct: 1496 EKEHQVLQDQLQEVY---ENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDL 1552
>gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skeletal muscle, fetal (Myosin heavy chain IIb) (MyHC-IIb) Length = 1939 Score = 37.4 bits (85), Expect = 0.010 Identities = 30/134 (22%), Positives = 61/134 (45%), Gaps = 13/134 (9%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 977 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDD 1037 Query: 116 LEYKLKCNKEENLC 129 LE L+ +E+ LC Sbjct: 1038 LEGSLE--QEKKLC 1049
Score = 34.7 bits (78), Expect = 0.066 Identities = 30/148 (20%), Positives = 65/148 (43%), Gaps = 35/148 (23%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAELAESRCQET 53 LK+ + ++A R +++ +L ++E LE TE ++AE + Sbjct: 1654 LKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDA 1713 Query: 54 DEQIRLMD-QNLKCLS-------DAEEKYSQKEDIYEE-------------EIKILTDKL 92 E+++L+ QN ++ D + + EDI +E + ++ ++L Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773 Query: 93 KEAETRAEFTERLVAKLEKTTDDLEYKL 120 K+ + + ER+ +E+T DL+ +L Sbjct: 1774 KKEQDTSAHLERMKKNMEQTVKDLQLRL 1801
Score = 34.7 bits (78), Expect = 0.066 Identities = 27/117 (23%), Positives = 53/117 (45%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ +E+++ + + Sbjct: 1032 EQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEM 1091 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L E +++IK L +++E E E AK EK DL +L+ Sbjct: 1092 SNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Score = 32.0 bits (71), Expect = 0.43 Identities = 26/144 (18%), Positives = 70/144 (48%), Gaps = 4/144 (2%) Query: 3 LQEIQLKEAK-HIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 L ++Q++E K + +A K E+ ++ +EG LE ++ E ++ + ++L Sbjct: 1011 LDDLQMEEDKVNTLTKAKTKLEQ---QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 ++ + +++ ++K E E+ L K+++ + A ++ + +L+ ++LE +++ Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIE 1127 Query: 122 CNKEENLCTQRMLYQTLLDLNEIS 145 + ++ +L EIS Sbjct: 1128 AERASRAKAEKQRSDLSRELEEIS 1151
Score = 31.6 bits (70), Expect = 0.56 Identities = 51/230 (22%), Positives = 89/230 (38%), Gaps = 45/230 (19%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL-KCLSDAEE-- 72 EE R+ EE + + L+ +L + +E E + + + K S+ + Sbjct: 1317 EELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWR 1376 Query: 73 -KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEEN 127 KY Q+ + EE K L +L++AE E A LEKT L+ Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQ---------- 1426 Query: 128 LCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQEL 187 NE+ + I + + D+ + FD A+ + E T EL Sbjct: 1427 --------------NEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQ-KYEETQAEL 1471 Query: 188 LVNQNPIVQPLASRRLTRNLYKCIKKAMKQ-----KQLRRGVKEVQKFVN 232 +Q SR L+ L+K +K A ++ + L+R K +Q+ ++ Sbjct: 1472 EASQK------ESRSLSTELFK-VKNAYEESLDHLETLKRENKNLQQEIS 1514
Score = 28.9 bits (63), Expect = 3.6 Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 + ++K K AEEA+ + K ++ +LE EERA++AES+ + +++ + + Sbjct: 1876 QTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKL--RVKSREVHT 1933 Query: 65 KCLSD 69 K +S+ Sbjct: 1934 KVISE 1938
Score = 28.9 bits (63), Expect = 3.6 Identities = 30/138 (21%), Positives = 61/138 (44%), Gaps = 22/138 (15%) Query: 5 EIQLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQETDEQ 56 +++L EA+ +A + +K +++ ++ +E ++E ++ A E R +E Q Sbjct: 1798 QLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFT 102 +N+ L D +K K Y+ + + L +L+EAE RA+ Sbjct: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIA 1917 Query: 103 ERLVAKLEKTTDDLEYKL 120 E V KL + ++ K+ Sbjct: 1918 ESQVNKLRVKSREVHTKV 1935
Score = 27.7 bits (60), Expect = 8.1 Identities = 31/131 (23%), Positives = 61/131 (46%), Gaps = 15/131 (11%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQETDEQIR 58 + ++ K + + K +E+ K+V + + DL+ + +AE AE RC + + Sbjct: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADALADAEERCDQLIKTKI 917 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 ++ +K + E+ +E+I E + + L D+ E + + E +AK+EK Sbjct: 918 QLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 974 Query: 116 LEYKLKCNKEE 126 E K+K EE Sbjct: 975 TENKVKNLTEE 985
>gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen) Length = 1756 Score = 37.4 bits (85), Expect = 0.010 Identities = 49/187 (26%), Positives = 88/187 (47%), Gaps = 16/187 (8%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE----RAELAESRCQE--TDE 55 EL+ +QL+ E D E V ++++ IE D +E R EL R Q+ + Sbjct: 970 ELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREA 1029 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEE-IKILTDKLKEAETRA-----EFTERLVAKL 109 ++ L+ Q + L AEEK +E + E+E +K+ D EAE + + ++L K Sbjct: 1030 EVLLLQQRVAAL--AEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ 1087 Query: 110 EKTTDDLEYKLK-CNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRF 168 E+ L+ KLK KE + ++ + +L + + ++ ++S+ + R D+ K R Sbjct: 1088 EEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLT-RQYEDEAAKARA 1146 Query: 169 DGPEAQE 175 E E Sbjct: 1147 SQREKTE 1153
Score = 32.7 bits (73), Expect = 0.25 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 15/139 (10%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERA------ELAESRCQETDE 55 E+Q +Q + A EEA+ + + + V+++ D + E A E + R Q + Sbjct: 1419 EVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEG 1478 Query: 56 QIRLMDQNLKCLSDAE--EKYSQKEDIY------EEEIKILTDKLKEAETRAEFTERLVA 107 ++ + + L L AE EK E + E+EI+ L L+E + V+ Sbjct: 1479 ELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVS 1538 Query: 108 KLEKTTDDLEY-KLKCNKE 125 +LE +LE+ K +KE Sbjct: 1539 RLEARLSELEFHNSKSSKE 1557
>gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa) Length = 1941 Score = 37.0 bits (84), Expect = 0.013 Identities = 33/158 (20%), Positives = 67/158 (42%), Gaps = 11/158 (6%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 55 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 922 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 979 Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISN 153 LE L+ K+ + +R + DL + I N Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIEN 1077
Score = 36.6 bits (83), Expect = 0.017 Identities = 28/117 (23%), Positives = 53/117 (45%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ DE+++ + + Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L E +++IK L +++E E E AK EK DL +L+ Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Score = 36.2 bits (82), Expect = 0.023 Identities = 36/172 (20%), Positives = 67/172 (38%), Gaps = 56/172 (32%) Query: 5 EIQLKEAKHIAEEADRKY---------------------EEVPRKLVIIE---------- 33 EIQL A +A EA R Y E++ +L ++E Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691 Query: 34 ----GDLECTEERAELAESRCQETDEQIRLM--------DQNLKCLSDAEEKYSQKEDIY 81 LE TE ++AE + E+++L+ + K +D + + EDI Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL 1751 Query: 82 EE-------------EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 +E + ++ ++LK+ + + ER+ +E+T DL+ +L Sbjct: 1752 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Score = 33.5 bits (75), Expect = 0.15 Identities = 32/138 (23%), Positives = 63/138 (45%), Gaps = 22/138 (15%) Query: 5 EIQLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQETDEQ 56 +++L EA+ +A + +K +++ ++ +EG++E ++R A E R +E Q Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFT 102 +N+ L D +K K Y+ + + L +L+EAE RA+ Sbjct: 1860 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIA 1919 Query: 103 ERLVAKLEKTTDDLEYKL 120 E V KL + ++ K+ Sbjct: 1920 ESQVNKLRVKSREVHTKV 1937
Score = 31.6 bits (70), Expect = 0.56 Identities = 26/144 (18%), Positives = 69/144 (47%), Gaps = 4/144 (2%) Query: 3 LQEIQLKEAK-HIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 L ++Q +E K + +A K E+ ++ +EG LE ++ E ++ + ++L Sbjct: 1013 LDDLQAEEDKVNTLTKAKIKLEQ---QVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 +++ + + +++ +K E EI L K+++ + ++ + +L+ ++LE +++ Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129 Query: 122 CNKEENLCTQRMLYQTLLDLNEIS 145 + ++ +L EIS Sbjct: 1130 AERASRAKAEKQRSDLSRELEEIS 1153
Score = 30.0 bits (66), Expect = 1.6 Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 12/124 (9%) Query: 30 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA-EEKYSQKEDIYEE----- 83 ++ E +C E AEL S+ ++ R + L + +A EE Q E + E Sbjct: 1458 ILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512 Query: 84 -EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 142 EI LT+++ E R E++ ++E+ +L+ L+ + + + + L+LN Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572 Query: 143 EISS 146 ++ S Sbjct: 1573 QVKS 1576
Score = 29.6 bits (65), Expect = 2.1 Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 2/65 (3%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 + ++K K AEEA+ + K ++ +LE EERA++AES+ + +++ + + Sbjct: 1878 QAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL--RVKSREVHT 1935 Query: 65 KCLSD 69 K +S+ Sbjct: 1936 KVISE 1940
Score = 28.9 bits (63), Expect = 3.6 Identities = 64/278 (23%), Positives = 115/278 (41%), Gaps = 51/278 (18%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQET 53 E Q+I+ + AK EA RK E+ K+V + + DL+ + +AE AE RC + Sbjct: 861 EFQKIKDELAK---SEAKRK--ELEEKMVTLLKEKNDLQL-QVQAEAEGLADAEERCDQL 914 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLE 110 + ++ +K + E+ +E+I E + + L D+ E + + E +AK+E Sbjct: 915 IKTKIQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 Query: 111 KTTDDLEYKLKCNKE--------------ENLCTQRMLYQTLLDL-------NEISSVSI 149 K E K+K E E Q QTL DL N ++ I Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKI 1031 Query: 150 QISNY--SFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLASRRLTRNL 207 ++ G + + K R D A+ + + QE +++ Q L +L + Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQL-DEKLKKKE 1090 Query: 208 YKCIKKAMKQK-------QLRRGVKEVQKFVNKGEKGI 238 ++ K + QL++ +KE+Q + + E+ I Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI 1128
>gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (HuGBP-2) Length = 591 Score = 37.0 bits (84), Expect = 0.013 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Query: 10 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 69 +AK + ++ E+V L+ + L E+ E+ + + + +++++ K Sbjct: 454 QAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQK---K 510 Query: 70 AEEKYSQKEDIYEEEIKILTDKLK--EAETRAEFTERLVAKLEK 111 EE QKE Y+E +K LT+K++ A+ AE + L KL++ Sbjct: 511 NEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQE 554
>gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 2) (PTPRF-interacting protein alpha 2) Length = 1257 Score = 37.0 bits (84), Expect = 0.013 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 Q+ E + + E+ + + ++ +L + + E+ AE A +T+E N K Sbjct: 269 QIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEM------NTKY 322 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 D E +QKED+ EE I L + A+ + + KLE + E L+ +E+ Sbjct: 323 QRDIREAMAQKEDM-EERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEK 381 Query: 127 NLCTQRML 134 N Q L Sbjct: 382 NRQLQERL 389
Score = 33.5 bits (75), Expect = 0.15 Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 2/119 (1%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ME + QL+E +AEE ++ L +E +L AE +E++R + Sbjct: 378 MEEKNRQLQERLELAEEKLQQTMRKAETLPEVEAELAQRIAALTKAEETHGNIEERMRHL 437 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 + L+ + ++ Q+E + EE K L+D + T E ERL L++ LE K Sbjct: 438 EGQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLT--ESNERLQLHLKERMAALEEK 494
>gi|1706487|sp|P98082|DAB2_HUMAN Disabled homolog 2 (Differentially expressed protein 2) (DOC-2) Length = 770 Score = 36.6 bits (83), Expect = 0.017 Identities = 34/162 (20%), Positives = 61/162 (37%), Gaps = 19/162 (11%) Query: 178 CSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKG 237 C GE +Q + +PL ++L++ I K+++ ++ ++E K V G + Sbjct: 138 CGGEGQHQFFAIKTGQQAEPLVVD--LKDLFQVIYNVKKKEEEKKKIEEASKAVENGSEA 195 Query: 238 IMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAG-------RKKRE--- 287 +M+L + T ++ + LFG + P + L D RE Sbjct: 196 LMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLNSEIDTNQNSLRENPF 255 Query: 288 -------ASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRE 322 SL T ++S P + F P P D R+ Sbjct: 256 LTNGITSCSLPRPTPQASFSPENAFSANLNFFPTPNPDPFRD 297
>gi|34395524|sp|Q92888|ARH1_HUMAN Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5) Length = 912 Score = 36.6 bits (83), Expect = 0.017 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 286 REASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKS 337 RE + S P+GP+ PP+ TD G ET P+ G E EPG+S Sbjct: 336 REPGADAPLELGDSSPQGPMSLESLAPPES-TDEGAETESPEPGDEGEPGRS 386
>gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 1) (PTPRF-interacting protein alpha 1) (LAR-interacting protein 1) (LIP.1) Length = 1202 Score = 36.6 bits (83), Expect = 0.017 Identities = 46/221 (20%), Positives = 87/221 (39%), Gaps = 20/221 (9%) Query: 10 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 69 E + I + R+ ++ +L + + EE + A + I+ + N K D Sbjct: 254 ELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARK------DLIKSEEMNTKLQRD 307 Query: 70 AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE----------KTTDDLEYK 119 E +QKED+ EE I L + A+ A L KLE + T+D + Sbjct: 308 VREAMAQKEDM-EERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQ 366 Query: 120 LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACS 179 L +E ++ L QTL + V +++ ++ G + Q EA Sbjct: 367 L---QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQL 423 Query: 180 GERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQL 220 E+ + Q + ++RL+ + K + ++ ++ QL Sbjct: 424 EEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQL 464
Score = 35.0 bits (79), Expect = 0.050 Identities = 37/156 (23%), Positives = 71/156 (45%), Gaps = 7/156 (4%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QL+E +AE+ ++ L +E +L AE R +E++R M+ L+ Sbjct: 366 QLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEE 425 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 + ++ Q+E + EE K L+D + + +E ERL L++ LE K +E Sbjct: 426 KNQELQRARQREKMNEEHNKRLSDTVD--KLLSESNERLQLHLKERMAALEDKNSLLREV 483 Query: 127 NLCTQRMLYQTLLDLNE----ISSVSIQISNYSFRG 158 ++ L +T D ++ I ++ ++ + RG Sbjct: 484 E-SAKKQLEETQHDKDQLVLNIEALRAELDHMRLRG 518
Score = 30.4 bits (67), Expect = 1.2 Identities = 25/124 (20%), Positives = 56/124 (45%), Gaps = 2/124 (1%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 EI K++ H + + K ++ +L + E L+ T +AE E +++ + + Sbjct: 349 EIANKDSMH--RQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAE 406 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 + + EE+ Q E EE+ + L + + E +RL ++K + +L+ + Sbjct: 407 ERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHL 466 Query: 125 EENL 128 +E + Sbjct: 467 KERM 470
>gi|12643957|sp|Q9Y618|NCOR2_HUMAN Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor-associating factor) (TRAC) (CTG repeat protein 26) (SMAP270) Length = 2517 Score = 36.6 bits (83), Expect = 0.017 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Query: 268 AQTAPQEPSKLGDAGRKKREASLSP-ETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRP 326 A +PQ+P L K+R A++ P + + PR P PP PP + L+P Sbjct: 953 ANASPQKPLDLKQL--KQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPP---QNLQP 1007 Query: 327 KMGSEREPGKSP---DAAPFPP 345 + + ++PG SP +P PP Sbjct: 1008 ESDAPQQPGSSPRGKSRSPAPP 1029
Score = 28.9 bits (63), Expect = 3.6 Identities = 15/40 (37%), Positives = 18/40 (45%) Query: 263 WRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPR 302 WRPG Q++ S G G R AS S + S PR Sbjct: 1827 WRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSPISPR 1866
Score = 27.7 bits (60), Expect = 8.1 Identities = 13/36 (36%), Positives = 15/36 (41%) Query: 310 PFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 P PP PP R + P SE +P AP P Sbjct: 780 PGPPTPPRRTSRAPIEPTPASEATGAPTPPPAPPSP 815
>gi|464486|sp|P35247|PSPD_HUMAN Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D) Length = 375 Score = 36.2 bits (82), Expect = 0.023 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETL 324 PGAA A P + G G K S+ + + P GP P PP P AGRE Sbjct: 69 PGAAGQAGM-PGQAGPVGPKGDNGSVGEPGPKGDTGPSGP-----PGPPGVPGPAGREGA 122 Query: 325 RPKMGS---EREPGKSPDAAP 342 K G+ + +PG +A P Sbjct: 123 LGKQGNIGPQGKPGPKGEAGP 143
>gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin-like protein) (Schwannomin) (Schwannomerlin) (Neurofibromin 2) Length = 595 Score = 36.2 bits (82), Expect = 0.023 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 21/119 (17%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 +++ +L K + EEA+R +E+ R+L+ ++ E A +A ++E L+ Sbjct: 333 QMERQRLAREKQMREEAERTRDELERRLLQMK-------EEATMANEALMRSEETADLL- 384 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 ++K I EEE K+L K EAE + + + E+ +E K+ Sbjct: 385 -------------AEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKV 430
>gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (ATM and Rad3 related interacting protein) Length = 791 Score = 36.2 bits (82), Expect = 0.023 Identities = 22/101 (21%), Positives = 54/101 (53%), Gaps = 3/101 (2%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN- 63 E+++ +A++ +E K + + +++I G+++ + ES +E L++Q Sbjct: 113 ELEVLQAQY--KELKEKMKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRSHFLLEQEK 170 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTER 104 + LSD E+++S+K + E++ ++ E T+ + +ER Sbjct: 171 TQALSDKEKEFSKKLQSLQSELQFKDAEMNELRTKLQTSER 211
>gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A) (Myosin containing PDZ domain) Length = 2054 Score = 35.8 bits (81), Expect = 0.030 Identities = 39/167 (23%), Positives = 70/167 (41%), Gaps = 24/167 (14%) Query: 2 ELQEIQ--LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 E EIQ L+E + E +K++ + + + + E A QE E+++ Sbjct: 1740 EKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQA 1799 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEF-----------TERLVAK 108 + ++ L E+ K + +E KI +E ETR EF RL Sbjct: 1800 LQSQVEFL---EQSMVDKSLVSRQEAKI-----RELETRLEFERTQVKRLESLASRLKEN 1851 Query: 109 LEKTTDDLEYKLKC---NKEENLCTQRMLYQTLLDLNEISSVSIQIS 152 +EK T++ + ++ KE+N QR L T ++ E++ + S Sbjct: 1852 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEAS 1898
Score = 35.8 bits (81), Expect = 0.030 Identities = 45/215 (20%), Positives = 96/215 (44%), Gaps = 33/215 (15%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E +L + + +EE+ R +++ +K + +L+ T+ E + R E +++ R D L Sbjct: 1408 ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1467 Query: 65 -KCLSDAEEKYSQKEDIYEEEIKILTD------KLKEAETR-AEFTERLV---------- 106 + +A+ + Q+E + E+ +L + +L+E + A FT+++V Sbjct: 1468 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1527 Query: 107 ----------AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSF 156 AK++K DLE K+K ++EE L Q Q L E + + +++ Sbjct: 1528 SQESKDEASLAKVKKQLRDLEAKVK-DQEEELDEQAGTIQML----EQAKLRLEMEMERM 1582 Query: 157 RGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQ 191 R + + R + E ++C + E+ + + Sbjct: 1583 RQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Score = 28.9 bits (63), Expect = 3.6 Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 5/118 (4%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QL++ K E RK E RK +E DLE E + ++ + ++I +L+ Sbjct: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRI----GDLQA 1934 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 + E + + ED+ ++ + K ++ + + E + ++LE D ++ L NK Sbjct: 1935 AIEDEMESDENEDLI-NSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNK 1991
>gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein kinase 1 (Rho-associated, coiled-coil containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 35.8 bits (81), Expect = 0.030 Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 32/154 (20%) Query: 3 LQEIQLKEAKHIAEEADR----KYEEVPRKLVIIEGDLECTEERAE--------LAESRC 50 L + Q+KE K EE +R K +E+ + + L+ E +AE L E Sbjct: 855 LYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYF 914 Query: 51 QETDEQIRLMDQNLKCLSDAEEKYSQKED----------IYEEEIKILTDKLKEAETRAE 100 + T E + +N + ++D + S+ E+ I E + LT+K+K+AE Sbjct: 915 ELTQESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEE-- 972 Query: 101 FTERLVAKLEKTTDDLEYKLKCNKEENLCTQRML 134 KLEK ++ LK E+N+ T+R L Sbjct: 973 ------YKLEK--EEEISNLKAAFEKNINTERTL 998
Score = 35.4 bits (80), Expect = 0.039 Identities = 48/214 (22%), Positives = 93/214 (43%), Gaps = 35/214 (16%) Query: 24 EVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIY 81 E + + + E + + EER E AE+R + ++Q ++D +LK E + ++ Sbjct: 706 EEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM 765 Query: 82 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 E+E+K LT +L++ E +RL+ + E T E E+ + + TLL+ Sbjct: 766 EDEVKNLTLQLEQ-----ESNKRLLLQNELKTQAFEADNLKGLEKQM---KQEINTLLEA 817 Query: 142 NEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLASR 201 + + +RG N+G+ + Q EA E+ + L Q Sbjct: 818 KRLLEFELAQLTKQYRG-----NEGQMRELQDQLEA---EQYFSTLYKTQ---------- 859 Query: 202 RLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGE 235 K +K+ +++K R +K++Q+ N+ E Sbjct: 860 ------VKELKEEIEEKN-RENLKKIQELQNEKE 886
Score = 30.0 bits (66), Expect = 1.6 Identities = 23/109 (21%), Positives = 53/109 (48%), Gaps = 12/109 (11%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E +LKE + E+A+ + ++ ++ +++ DL+ ++++ E + +++++ + L Sbjct: 717 EKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQL 776 Query: 65 KCLSDAEEKYSQKEDIYEEEIK---ILTDKLK--EAETRAEFTERLVAK 108 E+ S K + + E+K D LK E + + E L AK Sbjct: 777 -------EQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAK 818
>gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain containing protein 2) Length = 1411 Score = 35.8 bits (81), Expect = 0.030 Identities = 34/155 (21%), Positives = 73/155 (47%), Gaps = 17/155 (10%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVI------IEGDLECTEERAELAESRCQETDE 55 EL+ +L+ K I D K + +KL + ++ +E + ++ + + ++ +E Sbjct: 1146 ELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEE 1205 Query: 56 QIR--LMDQNLKCLSDAEEKYSQKEDIYEEEIKI------LTDKLKEAETRAEFTERLVA 107 +++ +++ K S+ +EK + E E K+ L + L + + ++R V+ Sbjct: 1206 ELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVS 1265 Query: 108 KLEKTTDDLEYK---LKCNKEENLCTQRMLYQTLL 139 +LEK TDDL + L+ + N +R L + L Sbjct: 1266 ELEKQTDDLRGEIAVLEATVQNNQDERRALLERCL 1300
Score = 31.2 bits (69), Expect = 0.73 Identities = 56/294 (19%), Positives = 121/294 (41%), Gaps = 45/294 (15%) Query: 2 ELQEIQLKEAKHIAE--EADRKYEEVPRKLVIIEGDLECTEERAELA----ESRCQETDE 55 ELQ++++++ + E K +V L + + E ++ + A E C+E Sbjct: 840 ELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKH 899 Query: 56 QIRLMDQNL----KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 111 Q+++ +N K L + EK + + E+ + ++L +A+ + E+ +L+ Sbjct: 900 QLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQG 959 Query: 112 TTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISS-------------------VSIQIS 152 ++L+ + K++ Q L +L E+ + +S+ + Sbjct: 960 NINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQN 1019 Query: 153 NYSFRGCCDDQNKGRFDGPEAQ-----EEACSGERTY---QELLV-------NQNPIVQP 197 NY Q + F G E++ ++ S E QE L+ NQN ++Q Sbjct: 1020 NYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQE 1079 Query: 198 LASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEV 251 L + + T KK + ++ + ++++QK + EK ++ IEE+ Sbjct: 1080 LKTAKATLE-QDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEI 1132
Score = 30.4 bits (67), Expect = 1.2 Identities = 38/144 (26%), Positives = 67/144 (46%), Gaps = 25/144 (17%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGD---LECTEERA--ELAESRCQETDEQIRL 59 E LKE K ++K EE+ ++ +E D ++ ++E+A +L + R TD ++R Sbjct: 708 ESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRA 767 Query: 60 MDQN----------------LKCLSDAEEKYSQKEDIYEEEIKILTDKLK--EAETRAEF 101 + + L+ S+A E QK EEE +IL + ET+ + Sbjct: 768 TELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQH 827 Query: 102 TERLVAKLEKTTDDLEYKLKCNKE 125 E L +++ T +L+ K+K KE Sbjct: 828 -EELNNRIQTTVTELQ-KVKMEKE 849
Score = 28.1 bits (61), Expect = 6.2 Identities = 29/134 (21%), Positives = 56/134 (41%), Gaps = 3/134 (2%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E QLKE + E + ++ ++ + + T + A++ ++ QI DQ + Sbjct: 466 EEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKI 525 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK---LEKTTDDLEYKLK 121 + L +K + + E+E + L K++ E +L K L++ L KLK Sbjct: 526 QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLK 585 Query: 122 CNKEENLCTQRMLY 135 E + Q L+ Sbjct: 586 NQSESHKQAQENLH 599
>gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 Length = 586 Score = 35.4 bits (80), Expect = 0.039 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 15/121 (12%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEER-----AELAESRCQETDEQIRL 59 +I+L+E + D +EGDLE +++ A LA ++ Q DE + Sbjct: 132 QIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLK 191 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 +D +C S E+ +K +YEEEI ETR + RLV + EYK Sbjct: 192 VDLENRCQSLTEDLEFRK-SMYEEEIN---------ETRRKHETRLVEVDSGRQIEYEYK 241 Query: 120 L 120 L Sbjct: 242 L 242
>gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2) Length = 1220 Score = 35.4 bits (80), Expect = 0.039 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 5/130 (3%) Query: 2 ELQEIQL-KEAKHIAEEADRKYEE--VPRKLVIIEGDLECTEERAELAESRCQETDEQIR 58 E +E++ K+ + +E+ RK+EE V K+ + G + +EE+AE + + + + Sbjct: 255 EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 D+ K E++ +K+ + +K + + L + + E +R + K ++LE Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA 374 Query: 119 KLKCNKEENL 128 K K +EE L Sbjct: 375 KRK--EEERL 382
Score = 31.2 bits (69), Expect = 0.73 Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 14/110 (12%) Query: 9 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 68 K+ K EE +++ ++ P K + + E + E E + +E +E+I+ +++ L+ Sbjct: 319 KKKKGEKEEKEKEKKKGPSKATV-KAMQEALAKLKEEEERQKREEEERIKRLEE-LEAKR 376 Query: 69 DAEEKYSQ------------KEDIYEEEIKILTDKLKEAETRAEFTERLV 106 EE+ Q +++ ++E K+LT +EA RAE T +L+ Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLL 426
>gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg) Length = 1809 Score = 35.4 bits (80), Expect = 0.039 Identities = 30/114 (26%), Positives = 56/114 (49%), Gaps = 17/114 (14%) Query: 2 ELQEIQLKEAKH---IAEEADRKYEEVPRKLVIIEGD-----LECTEERAELAESRCQET 53 EL+ Q+K AK EE D Y E KL++ E D L+ + ELAES+ + + Sbjct: 296 ELRTTQVKTAKESEKYREERDAVYSEY--KLIMSERDQVISELDKLQTEVELAESKLKSS 353 Query: 54 DEQIRLMDQNLKCLSDAEE-------KYSQKEDIYEEEIKILTDKLKEAETRAE 100 + + ++ ++ L ++ + +++ +I ++ K L +LKEA A+ Sbjct: 354 TSEKKAANEEMEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEAD 407
>gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax binding protein-181) Length = 718 Score = 35.0 bits (79), Expect = 0.050 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 14/123 (11%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +EL+ A++ E DR E + R + +ER AE + QE E+ R Sbjct: 83 VELERAASTSARNYEREVDRNQELLTR--------IRQLQEREAGAEEKMQEQLERNRQC 134 Query: 61 DQNLKCLSDAEEKYSQKEDIYE---EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 QNL A ++ +KED E I L ++ E + E V +LE +L+ Sbjct: 135 QQNLDA---ASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQ 191 Query: 118 YKL 120 +L Sbjct: 192 EQL 194
>gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond syndrome protein (CGI-97) Length = 250 Score = 35.0 bits (79), Expect = 0.050 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 12/95 (12%) Query: 53 TDEQIRLMDQNLKC----LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK 108 TD+Q + Q L +SD +E+++Q E ++ + I+ DK ET+ +T V Sbjct: 77 TDDQTEICKQILTKGEVQVSD-KERHTQLEQMFRDIATIVADKCVNPETKRPYT---VIL 132 Query: 109 LEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE 143 +E+ D+ Y +K NK T++ + + L E Sbjct: 133 IERAMKDIHYSVKTNKS----TKQQALEVIKQLKE 163
>gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 Length = 810 Score = 35.0 bits (79), Expect = 0.050 Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 40 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 99 +ER EL + R +ET++Q + + + KCL+ ++ EE++K +T + +E R Sbjct: 307 DERNELLK-RVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTK--ENSEMRE 363 Query: 100 EFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 140 + T K K+ +DL+ + + E L Q + Q ++D Sbjct: 364 KITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIID 404
>gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin Length = 1197 Score = 35.0 bits (79), Expect = 0.050 Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 33/211 (15%) Query: 26 PRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA--EEKYSQKEDI--- 80 P K V+++ LE E E+ E + Q +EQ+RL ++ L L A EE S+ +++ Sbjct: 454 PAKEVLLKDLLETRELLEEVLEGK-QRVEEQLRLRERELTALKGALKEEVASRDQEVEHV 512 Query: 81 ---YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQT 137 Y+ + + L +++A E K+ L+ +L+ EE Q M + Sbjct: 513 RQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKN 572 Query: 138 LLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQP 197 DL +Q+ R + E +EE GE+ + V Q + Q Sbjct: 573 KEDLRATKQELLQL---------------RMEKEEMEEEL--GEK----IEVLQRELEQA 611 Query: 198 LASRRLTRNLYKCIKKAMKQKQLRRGVKEVQ 228 AS TR + + +KK + + Q +KE+Q Sbjct: 612 RASAGDTRQV-EVLKKELLRTQ--EELKELQ 639
Score = 29.6 bits (65), Expect = 2.1 Identities = 31/128 (24%), Positives = 52/128 (40%), Gaps = 25/128 (19%) Query: 51 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE---IKILTDKLKEA-----ETRAEFT 102 QE + + R D + L EEK S+ E +EE +++LTD++ + R E Sbjct: 942 QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELM 1001 Query: 103 ERLVAK---------LEKTTDDLEYKLKCNKE--------ENLCTQRMLYQTLLDLNEIS 145 + A+ LE+ DL+ +L ++ L +Q L Q L E Sbjct: 1002 QERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQERLQAEERE 1061 Query: 146 SVSIQISN 153 +Q +N Sbjct: 1062 KTVLQSTN 1069
Score = 29.6 bits (65), Expect = 2.1 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 12/114 (10%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK-- 73 EEA R + ++ + LE ++ E+ E +EQ RL+D+ + L+ EK Sbjct: 797 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIG 856 Query: 74 ----------YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 +Q ED E+ + + D ++A+ A E+ L + D+++ Sbjct: 857 EDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQ 910
>gi|1350911|sp|P28702|RXRB_HUMAN Retinoic acid receptor RXR-beta (Retinoid X receptor beta) Length = 533 Score = 34.7 bits (78), Expect = 0.066 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 17/85 (20%) Query: 266 GAAQTAPQEPSK-----LGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAG 320 G QT EP + +GD+GR R SP++ + P+G P PP PP+ A Sbjct: 56 GEQQTPEPEPGEAGRDGMGDSGRDSR----SPDSSSPNPLPQGVPPPSPPGPPLPPSTA- 110 Query: 321 RETLRPKMGSEREPGKSPDAAPFPP 345 P +G P P P PP Sbjct: 111 -----PSLGGSGAP--PPPPMPPPP 128
>gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 Length = 1648 Score = 34.7 bits (78), Expect = 0.066 Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 19/131 (14%) Query: 19 DRKYEEVPRKLVIIEGDL---ECTEERAELAESRCQETDEQIRLMDQNLKCLSD-AEEKY 74 D E P+ + +L + ++ AE+ E++ + +E M Q ++ + A+++ Sbjct: 914 DTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEE----MMQGIQIAKEMAQQEL 969 Query: 75 SQKEDIYEEEIKILTDKLKEAETRAEFTE-------RLVAKLEKTTDDLEYKLKCNKE-- 125 S ++ YE +IK L +L+E R + E + +LEK LE ++ NK+ Sbjct: 970 SSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRL 1029 Query: 126 --ENLCTQRML 134 E L T++ L Sbjct: 1030 EMETLATKQAL 1040
>gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK) Length = 425 Score = 34.7 bits (78), Expect = 0.066 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 23/140 (16%) Query: 10 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ------IRLMDQN 63 EA+ +A +A + ++ + L +E LAE R E D++ +++ Sbjct: 73 EARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHA 132 Query: 64 LKCLSDAEEKYSQKEDIYEE----------EIKILTDKLKEAETRAEFTERLVAK----- 108 + + +AE+ ++ E +++E ++ L KLK A +++ L AK Sbjct: 133 TQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQL 192 Query: 109 --LEKTTDDLEYKLKCNKEE 126 L+KT DDL+ KL K E Sbjct: 193 EQLKKTVDDLQAKLTLAKGE 212
>gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2] Length = 2805 Score = 34.7 bits (78), Expect = 0.066 Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E ++ L++ E D+ EE + L E + EE+ + E + +++ + + Sbjct: 1415 LEQKDTALEQKDKALEPKDKDLEEKDKAL---EQKDKIPEEKDKALEQKDTALEQKDKAL 1471 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA---EFTERLVAKLEKTTDDLE 117 + K L + QKE I EE+ K L K++ E +A E LE+T E Sbjct: 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPE 1531 Query: 118 YKLKCNKEENLCTQR 132 K + ++++ +++ Sbjct: 1532 QKHQAQEQKDKVSEK 1546
Score = 32.3 bits (72), Expect = 0.33 Identities = 35/103 (33%), Positives = 42/103 (40%), Gaps = 13/103 (12%) Query: 238 IMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSK-LGDAGRKKREASLSPETKR 296 IM E T PI LG EAL PG +T PQEP K D + + SLSPE Sbjct: 1102 IMEAGEPTGPI---LGAEAL-------PGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAE 1151 Query: 297 SSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPD 339 S S P P P + G + +R P SP+ Sbjct: 1152 SLSVLSVPSPDTANQEPTPKSPCG--LTEQYLHKDRWPEVSPE 1192
Score = 31.2 bits (69), Expect = 0.73 Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 14/116 (12%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ-NLK 65 +L + + A+E+ K E P K ER + S + +++ + D+ K Sbjct: 355 ELAKTEKKAKESSEKPPEKPAK-----------PERVKTESSEALKAEKRKLIKDKVGKK 403 Query: 66 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L + K +K+D ++EIK +LK+ E R E E+ AK E+ D + +LK Sbjct: 404 HLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKE--EKKDAKKEEKRKDTKPELK 457
Score = 30.4 bits (67), Expect = 1.2 Identities = 29/128 (22%), Positives = 57/128 (44%), Gaps = 4/128 (3%) Query: 4 QEIQLKEAKHIAEEAD----RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 Q+ + E K + E D +K E + K ++ + E++ E + +++ + Sbjct: 1369 QKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKA 1428 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 ++ K L + ++ QK+ I EE+ K L K E + + E LE+ LE K Sbjct: 1429 LEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK 1488 Query: 120 LKCNKEEN 127 K +E++ Sbjct: 1489 EKIPEEKD 1496
Score = 28.9 bits (63), Expect = 3.6 Identities = 19/75 (25%), Positives = 29/75 (38%), Gaps = 3/75 (4%) Query: 275 PSKLGDAGRKKREASLSPETKRSSS---QPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 P+ D+G + ++ + PET+ S + F P T P+ G + Sbjct: 2500 PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKXGGVSGTHHPRPGHD 2559 Query: 332 REPGKSPDAAPFPPR 346 P PD P PPR Sbjct: 2560 PPPLPQPDXRPSPPR 2574
Score = 28.9 bits (63), Expect = 3.6 Identities = 20/89 (22%), Positives = 41/89 (46%), Gaps = 5/89 (5%) Query: 10 EAKHIAEE-----ADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E KH A+E +++K + + +K + E E+ + E Q +++ + + Sbjct: 1531 EQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKT 1590 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLK 93 + EEK +K EE+++ L +K K Sbjct: 1591 RKPKMLEEKSPEKVKAMEEKLEALLEKTK 1619
>gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein) Length = 896 Score = 34.3 bits (77), Expect = 0.086 Identities = 20/95 (21%), Positives = 47/95 (49%) Query: 32 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 91 +E DL+ E+ + S Q+ ++++ + NL+ L +++ + D +E+ L ++ Sbjct: 352 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 411 Query: 92 LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 LKE + +L++ L+ E ++ +EE Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 446
>gi|464541|sp|P35241|RADI_HUMAN Radixin Length = 583 Score = 34.3 bits (77), Expect = 0.086 Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 6/145 (4%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 +L+ QL+ K E A+++ E + R+ + L+ EE+ A+ +E + +D Sbjct: 317 QLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELD 376 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD---LEY 118 Q K + E+ ++ EE + K+A + + E+L A+L + T LE Sbjct: 377 QERKRAKEEAERLEKERRAAEEAKSAIA---KQAADQMKNQEQLAAELAEFTAKIALLEE 433 Query: 119 KLKCNKEENLCTQRMLYQTLLDLNE 143 K +EE Q + DL + Sbjct: 434 AKKKKEEEATEWQHKAFAAQEDLEK 458
>gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor) (CG-1 antigen) Length = 1357 Score = 34.3 bits (77), Expect = 0.086 Identities = 32/134 (23%), Positives = 59/134 (44%), Gaps = 11/134 (8%) Query: 2 ELQEIQL----KEAKHIAEEADRKYEEVPRKLVIIE-----GDLECTEERAELAESRCQE 52 E+Q++Q + K + E+ ++ +E KL +E G ++ + EL R + Sbjct: 713 EVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN 772 Query: 53 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 112 + + D LK + + ++ + ++ I K+K E E VA EKT Sbjct: 773 SSLTKEVQD--LKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKT 830 Query: 113 TDDLEYKLKCNKEE 126 DL+ ++K KEE Sbjct: 831 VQDLKQEIKALKEE 844
Score = 31.6 bits (70), Expect = 0.56 Identities = 51/290 (17%), Positives = 118/290 (40%), Gaps = 45/290 (15%) Query: 1 MELQEIQLKEAKHIA-------EEADRKYEEVP---RKLVI--------IEGDLECTEER 42 ++ +E+Q K A+ A +EA+R++EEV RK ++ E Sbjct: 469 LQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENE 528 Query: 43 AELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK--------- 93 + S+ +T + ++Q L L ++E+K KE+ + +++ + ++ + Sbjct: 529 VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQF 588 Query: 94 --------EAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEIS 145 A AE +++A+ +K E L ++ + L ++ + + ++N + Sbjct: 589 HSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSL-ASERDRLTSKEEELKDIQNMNFLL 647 Query: 146 SVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGE---RTYQELLVNQNPIVQPLASRR 202 +Q + ++Q + + Q+ + R +E L Q+ I + + Sbjct: 648 KAEVQ----KLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQL--QHEISNKMEEFK 701 Query: 203 LTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVL 252 + + K +K +++ Q + + V + EK I E +EE+L Sbjct: 702 ILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
>gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kinase (CRIK) (Rho-interacting, serine/threonine kinase 21) Length = 2027 Score = 34.3 bits (77), Expect = 0.086 Identities = 47/220 (21%), Positives = 84/220 (38%), Gaps = 66/220 (30%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLV------------------------------- 30 +L E +L+E++ AEE RK E KL+ Sbjct: 583 DLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQ 642 Query: 31 -----IIEGDLECTE---------ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY-- 74 ++ E TE ERAE + Q ++ + + L + EEK+ Sbjct: 643 EKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHRE 702 Query: 75 ------------SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD-----LE 117 QKE YEE+IK+L +++K+ E E ++ + E+ + E Sbjct: 703 AQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSE 762 Query: 118 YKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFR 157 K N ++ R L Q +++L+E + ++ S ++ R Sbjct: 763 QKAMINAMDSKI--RSLEQRIVELSEANKLAANSSLFTQR 800
Score = 30.8 bits (68), Expect = 0.95 Identities = 32/152 (21%), Positives = 63/152 (41%), Gaps = 11/152 (7%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAE---------LAESRCQ--ET 53 E+ LK+ + EE + + +K + + LE +R E L+E + Sbjct: 711 EVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAM 770 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 113 D +IR ++Q + LS+A + + + +K + + E + + E KLE Sbjct: 771 DSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQN 830 Query: 114 DDLEYKLKCNKEENLCTQRMLYQTLLDLNEIS 145 LE +L+ ++ + L + L E+S Sbjct: 831 RKLEEQLEKISHQDHSDKNRLLELETRLREVS 862
>gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1) Length = 4684 Score = 34.3 bits (77), Expect = 0.086 Identities = 48/257 (18%), Positives = 100/257 (38%), Gaps = 55/257 (21%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 + ++++ K AE+ R+ +V ++L + LE ETD Q L+D+ L Sbjct: 2301 DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE--------------ETDHQKNLLDEEL 2346 Query: 65 KCL-SDAEEKYSQKEDIYEE--EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + L ++A E Q+ + EE +++ ++L + + R E R + +K Sbjct: 2347 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDN-------- 2398 Query: 122 CNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGE 181 TQR L + + +++ + ++S A +EA Sbjct: 2399 --------TQRFLQEEAEKMKQVAEEAARLS-------------------VAAQEAARLR 2431 Query: 182 RTYQELLVNQNPIVQPLASRRLTRNLYKCIKKA---MKQKQLRRGVKEVQKFVNKGEKGI 238 + +E L Q + + + ++ KA + Q+Q ++ ++ E+ Sbjct: 2432 QLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMA 2491 Query: 239 MVLAEDTLPIEEVLGPE 255 LAE+T + L E Sbjct: 2492 QQLAEETQGFQRTLEAE 2508
Score = 32.7 bits (73), Expect = 0.25 Identities = 66/303 (21%), Positives = 125/303 (41%), Gaps = 39/303 (12%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQ-ETDEQIRLMD 61 LQE + A+ + EEA+R+ ++ + + E E AE R Q + +E +RL Sbjct: 1733 LQEEHVAVAQ-LREEAERRAQQ--------QAEAERAREEAERQLERWQLKANEALRLRL 1783 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 Q AEE QK E K + +EA R + E+ V + E +LE + + Sbjct: 1784 Q-------AEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQ 1836 Query: 122 CNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEA--QEEACS 179 E QR+ + L I++ + +G +Q + + A Q EA + Sbjct: 1837 L--AEGTAQQRLAAEQEL---------IRLRAETEQG---EQQRQLLEEELARLQREAAA 1882 Query: 180 GERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKG-- 237 + QEL + + ++ + ++ +K +R E +F E+ Sbjct: 1883 ATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR 1942 Query: 238 IMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRS 297 + LAE+ ++ +A R R A + ++ + +G+A R K EA ++ + K + Sbjct: 1943 LRALAEEAKRQRQLAEEDA----ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEA 1998 Query: 298 SSQ 300 ++ Sbjct: 1999 ENE 2001
Score = 30.4 bits (67), Expect = 1.2 Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 7/106 (6%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES---RCQETDEQIR 58 +L E L + + +AE+ ++ + ++ ++ + E +++ ELA+ R QE EQ+ Sbjct: 2432 QLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMA 2491 Query: 59 LM----DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 Q + +AE + + E +K+ ++ A+ RAE Sbjct: 2492 QQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2537
Score = 30.0 bits (66), Expect = 1.6 Identities = 48/228 (21%), Positives = 100/228 (43%), Gaps = 25/228 (10%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES--RCQETDEQIRLMDQ 62 E++L + AE+ R E+ +LE +R AE R +E +E+++ Sbjct: 2082 ELELGRIRSNAEDTLRSKEQA---------ELEAARQRQLAAEEERRRREAEERVQ---- 2128 Query: 63 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK-LEKTTDDLEYKLK 121 K L+ AEE+ +++ EE++ L K++EA + E E+ A+ L+ + + +L+ Sbjct: 2129 --KSLA-AEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQ 2185 Query: 122 CNKEENLCTQRMLYQTLLD-LNEISSVSIQISN--YSFRGCCDDQNKGRFDGPEAQEEAC 178 ++ + + Q L L + SV ++ + R ++ + R +A+ EA Sbjct: 2186 AEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARV---QAEREAA 2242 Query: 179 SGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKE 226 R +E + + +R + + ++K +Q+ RR E Sbjct: 2243 QSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAE 2290
>gi|52001469|sp|P04280|PRP1_HUMAN Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H] Length = 392 Score = 34.3 bits (77), Expect = 0.086 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 5/97 (5%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDA-GRKKREASLSPETKRSSSQPRGPVRTHFPF 311 GP G+ + P PQ P G G + S S + +P+GP + Sbjct: 293 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARAPPGKPQGPPQQEGNN 352 Query: 312 PPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTG 348 P PP AG +P + P P P PP+ G Sbjct: 353 PQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGG 385
Score = 33.1 bits (74), Expect = 0.19 Identities = 23/93 (24%), Positives = 31/93 (33%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFP 312 GP G+ + P PQ P G + S + +P+GP P Sbjct: 171 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSQSPRSPPGKPQGPPPQGGNQP 230 Query: 313 PKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 PP G+ P+ G R G P P P Sbjct: 231 QGPPPPPGKPQGPPQQGGNRPQGPPPPGKPQGP 263
Score = 31.2 bits (69), Expect = 0.73 Identities = 22/93 (23%), Positives = 30/93 (32%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFP 312 GP G+ + P PQ P G + S + +P+GP P Sbjct: 110 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSQSPRSPPGKPQGPPPQGGNQP 169 Query: 313 PKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 PP G+ P G + G P P P Sbjct: 170 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 202
Score = 30.8 bits (68), Expect = 0.95 Identities = 24/97 (24%), Positives = 32/97 (32%), Gaps = 1/97 (1%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFP 312 GP G+ + P PQ P G + S + +P+GP P Sbjct: 232 GPPPPPGKPQGPPQQGGNRPQGPPPPGKPQGPPPQGDKSRSPQSPPGKPQGPPPQGGNQP 291 Query: 313 PKPPTDAGRETLRPKMGSEREPGKSPDAAP-FPPRTG 348 PP G+ P G + G P P PP G Sbjct: 292 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQG 328
Score = 30.8 bits (68), Expect = 0.95 Identities = 22/93 (23%), Positives = 30/93 (32%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFP 312 GP G+ + P PQ P G + S + +P+GP P Sbjct: 49 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 108 Query: 313 PKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 PP G+ P G + G P P P Sbjct: 109 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 141
>gi|37999491|sp|Q07912|ACK1_HUMAN Activated CDC42 kinase 1 (ACK-1) Length = 1036 Score = 34.3 bits (77), Expect = 0.086 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 5/75 (6%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 PQ P ++ R R P + S + P + +P P PP RE L P+ Sbjct: 736 PQVPPRVPIPPRPTR-----PHVQLSPAPPGEEETSQWPGPASPPRVPPREPLSPQGSRT 790 Query: 332 REPGKSPDAAPFPPR 346 P P ++P PPR Sbjct: 791 PSPLVPPGSSPLPPR 805
>gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B Length = 1637 Score = 33.9 bits (76), Expect = 0.11 Identities = 58/250 (23%), Positives = 106/250 (42%), Gaps = 38/250 (15%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 67 ++ AK E +K RK + E ++RA+L + +ETDE ++ + Sbjct: 541 IRRAKQDLERLKKKEVRQRRK----SPEKEAFKKRAKLQQENSEETDENEAEEEEEERDE 596 Query: 68 SDAEE---KYSQKEDIYEEEIKILTD---KLKEAETRAEFTERLVAKLE---KTTDDLEY 118 S EE + + ED EE + +D + KE +A+ + L ++E K D+LE Sbjct: 597 SGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLAD-LTCEIEIKQKLIDELE- 654 Query: 119 KLKCNKEENLCTQRMLYQTLLDL--NEISSVSIQ----ISNYSFRGCCDDQ--NKGRFDG 170 N + L T + Y+ L L N+I ++ + N S C ++ NK + D Sbjct: 655 ----NSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADY 710 Query: 171 PEAQEE-------ACSGERTYQELLVNQNPIVQPL----ASRRLTRNLYKCIKKAMKQKQ 219 + E + ++ + LL NQ+ + L A + + K M+++Q Sbjct: 711 EKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQ 770 Query: 220 LRRGVKEVQK 229 RR + E ++ Sbjct: 771 QRRRLVETKR 780
>gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1 protein) Length = 2230 Score = 33.9 bits (76), Expect = 0.11 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Query: 12 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAE 71 K+ ++ D +++E+ +KL + E + R + AE + + Q+ M L+ Sbjct: 1549 KNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKEL 1608 Query: 72 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 E + EEE+K L D+L E+E+ A+ E L K E+ ++ +L EE Sbjct: 1609 EHVNLSVKSKEEELKALEDRL-ESESAAKLAE-LKRKAEQKIAAIKKQLLSQMEE 1661
Score = 33.9 bits (76), Expect = 0.11 Identities = 33/143 (23%), Positives = 65/143 (45%), Gaps = 24/143 (16%) Query: 5 EIQLKEAKHIAEEADRKYEEVP---RKLVIIEGDLECTEERAELAES-----------RC 50 E++ KEA E+ + EE+ ++ ++G++E + + E ES R Sbjct: 1468 ELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI 1527 Query: 51 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKL-------KEAETRAEFTE 103 E ++ I ++ L++ + Y+Q++DI E K L KL +E + R + E Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQQKDI---EHKELVQKLQHFQELGEEKDNRVKEAE 1584 Query: 104 RLVAKLEKTTDDLEYKLKCNKEE 126 + LE ++ +L+ K+E Sbjct: 1585 EKILTLENQVYSMKAELETKKKE 1607
Score = 33.5 bits (75), Expect = 0.15 Identities = 33/131 (25%), Positives = 65/131 (49%), Gaps = 20/131 (15%) Query: 2 ELQEIQLKE---AKHIAEEADRKYEEVPRKL--VIIEGDLECTEERAELAESRCQETDEQ 56 E ++++LK K + E + + + ++L I E + E AEL ES +ET++ Sbjct: 1982 EQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQL 2041 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 ++ + + L ++Y + D EEE +T K+++ +T+ E +L+K Sbjct: 2042 LKKIAEKDDDLKRTAKRYEEILDAREEE---MTAKVRDLQTQLE-------ELQK----- 2086 Query: 117 EYKLKCNKEEN 127 +Y+ K +EEN Sbjct: 2087 KYQQKLEQEEN 2097
Score = 31.2 bits (69), Expect = 0.73 Identities = 26/140 (18%), Positives = 53/140 (37%), Gaps = 31/140 (22%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEG-------DLECTEERAELAESRCQETDEQIRL 59 +L+ + + EE D + +E K++ +E +LE ++ E + +E+++ Sbjct: 1565 KLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624 Query: 60 MDQNL------------------------KCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 95 ++ L + LS EEK Q + E + L KL+E Sbjct: 1625 LEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQER 1684 Query: 96 ETRAEFTERLVAKLEKTTDD 115 E E + +E + + Sbjct: 1685 EREVHILEEKLKSVESSQSE 1704
Score = 31.2 bits (69), Expect = 0.73 Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 6/122 (4%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E+ LKE +E E + + EG+L+ + ++ +S T EQ + ++ L Sbjct: 762 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL 821 Query: 65 -----KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 K L E+ + + E E + D E + + L+ +LEK ++E K Sbjct: 822 AQLQQKLLDLETERILLTKQVAEVEAQ-KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQK 880 Query: 120 LK 121 +K Sbjct: 881 VK 882
Score = 30.0 bits (66), Expect = 1.6 Identities = 26/123 (21%), Positives = 55/123 (44%), Gaps = 16/123 (13%) Query: 11 AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC---- 66 A+H+ +E + + + L + D++ T + EL CQ +++I+ +D L Sbjct: 1813 AQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT---CQILEQKIKELDSCLVRQKEV 1869 Query: 67 ----LSDAEEKYS-----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 + + KY Q+ D + ++L + +E +L++ +E +DLE Sbjct: 1870 HRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLE 1929 Query: 118 YKL 120 +KL Sbjct: 1930 FKL 1932
Score = 30.0 bits (66), Expect = 1.6 Identities = 55/242 (22%), Positives = 99/242 (40%), Gaps = 12/242 (4%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 +E RK +E+ +KL E + + E+ ++A + Q +I + + L+ EE Sbjct: 487 KELARKEQELTKKLQTREREFQ---EQMKVALEKSQSEYLKISQEKEQQESLA-LEELEL 542 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK-----CNKEENLCT 130 QK+ I E L D +EAET L + LEK+ + + + K E+N Sbjct: 543 QKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 602 Query: 131 QRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVN 190 + + E+ S+ Q + + + E E C E+ + LL + Sbjct: 603 KEITVMVEKHKTELESLKHQ-QDALWTEKLQVLKQQYQTEMEKLREKCEQEK--ETLLKD 659 Query: 191 QNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEE 250 + I Q + L K K + + L + EV K +K E+ + VL + T +++ Sbjct: 660 KEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ 719 Query: 251 VL 252 L Sbjct: 720 EL 721
>gi|52001468|sp|P02812|PRB2_HUMAN Basic salivary proline-rich protein 2 (Salivary proline-rich protein) (Con1 glycoprotein) [Contains: Basic peptide P-F] Length = 382 Score = 33.9 bits (76), Expect = 0.11 Identities = 26/97 (26%), Positives = 36/97 (37%), Gaps = 5/97 (5%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDA-GRKKREASLSPETKRSSSQPRGPVRTHFPF 311 GP G+ + P PQ P G G + S S + +P+GP + Sbjct: 283 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN 342 Query: 312 PPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTG 348 P PP AG +P + P P P PP+ G Sbjct: 343 PQGPPPPAGGNPQQP----QAPPAGQPQGPPRPPQGG 375
Score = 30.8 bits (68), Expect = 0.95 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 10/80 (12%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 PQ P GD K +++ SP K P+G + P PP G+ P G Sbjct: 187 PQGPPPQGD---NKSQSARSPPGKPQGPPPQGGNQ-----PQGPPPPPGKPQGPPPQGGN 238 Query: 332 REPGKSPDAAPF--PPRTGA 349 + G P P PP+ G+ Sbjct: 239 KSQGPPPPGKPQGPPPQGGS 258
Score = 30.8 bits (68), Expect = 0.95 Identities = 22/93 (23%), Positives = 30/93 (32%) Query: 253 GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFP 312 GP G+ + P PQ P G + S + +P+GP P Sbjct: 36 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP 95 Query: 313 PKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 PP G+ P G + G P P P Sbjct: 96 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 128
Score = 30.0 bits (66), Expect = 1.6 Identities = 23/74 (31%), Positives = 27/74 (36%), Gaps = 8/74 (10%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 PQ P GD K +S SP K P+GP P PP G+ P G Sbjct: 125 PQGPPPQGD---NKSRSSRSPPGK-----PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 176 Query: 332 REPGKSPDAAPFPP 345 + G P P P Sbjct: 177 KPQGPPPPGKPQGP 190
Score = 28.9 bits (63), Expect = 3.6 Identities = 22/80 (27%), Positives = 30/80 (37%), Gaps = 7/80 (8%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 P +P G K +S SP +P+GP P PP G+ P G Sbjct: 246 PGKPQGPPPQGGSKSRSSRSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 300 Query: 332 REPGKSPDAAPF--PPRTGA 349 + G P P PP+ G+ Sbjct: 301 KPQGPPPPGKPQGPPPQGGS 320
>gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP-E protein) Length = 2663 Score = 33.5 bits (75), Expect = 0.15 Identities = 31/156 (19%), Positives = 72/156 (46%), Gaps = 17/156 (10%) Query: 4 QEIQLKEAKHIAEEADR-KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 62 +++ +K+ + E + K + RK + L+ E + +R QE+ E+I++M + Sbjct: 1533 EQLNIKQISEVQENVNELKQFKEHRKAK--DSALQSIESKMLELTNRLQESQEEIQIMIK 1590 Query: 63 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE---------TRAEFTERLVAKLEKTT 113 + + +E + D +E K + K+KE++ T T+ + ++E Sbjct: 1591 EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650 Query: 114 DDLEYKLKCNKE----ENLCTQRMLYQTLLDLNEIS 145 + E + K N E EN+ ++L++ L ++ ++ Sbjct: 1651 EQFETQ-KLNLENIETENIRLTQILHENLEEMRSVT 1685
Score = 30.4 bits (67), Expect = 1.2 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Query: 41 ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 ER L E + QE+ E+I+ + + L +E K D +E I+ K++E++++ E Sbjct: 1329 ERLRLNE-KFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQE 1387 Query: 101 FTERLVAKLEKTT 113 + + K +TT Sbjct: 1388 QSLNMKEKDNETT 1400
>gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin condensation inducer in the nucleus (Acinus) Length = 1341 Score = 33.5 bits (75), Expect = 0.15 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 18/116 (15%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRK-------------LVIIEGDLECTEERAELAE 47 +EL +++ I+EE +E PRK + EG EE + Sbjct: 196 LELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETP 255 Query: 48 SRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 103 SR + ++R D+NLK + EE+ ++ED EEE K +EA EF E Sbjct: 256 SR----NLRVRA-DRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKE 306
>gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (Cut-like 2) Length = 1505 Score = 33.5 bits (75), Expect = 0.15 Identities = 62/325 (19%), Positives = 121/325 (37%), Gaps = 68/325 (20%) Query: 48 SRCQETDEQIRLMDQNLKC----LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 103 +R E +E+I+++ LK L + KY ++ +E+ ++ L++A RAE + Sbjct: 217 ARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQ 276 Query: 104 RLVAKLEK--TTDDLEYKLKCNKEE---------NLCT-----------QRMLYQTLLDL 141 R V L + + + +L C + LC+ R + + L D+ Sbjct: 277 REVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALASKDREILRLLKDV 336 Query: 142 NEISSVSIQISNYSFRGCCD--DQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLA 199 + S ++ S D Q + + E EE + Y+E+ Sbjct: 337 QHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEI------------ 384 Query: 200 SRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFG 259 + ++ K +K A L +G+ K E +++ E P ++ L Sbjct: 385 --KTELSILKAMKLASSTCSLPQGMA-------KPEDSLLIAKEAFFPTQKFL------- 428 Query: 260 RVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDA 319 +P + ++PS+ D+ + S + + P GP P P P Sbjct: 429 --LEKPSLLASPEEDPSE-DDSIKDSLGTEQSYPSPQQLPPPPGP---EDPLSPSP---- 478 Query: 320 GRETLRPKMGSEREPGKSPDAAPFP 344 G+ L P +G + ++ +PFP Sbjct: 479 GQPLLGPSLGPDGT--RTFSLSPFP 501
Score = 29.3 bits (64), Expect = 2.8 Identities = 26/121 (21%), Positives = 51/121 (42%), Gaps = 9/121 (7%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGD--LECTEERAELAE----SRCQETDEQIRLMD 61 L++A AE A R+ E + +L + L C + + + C + L Sbjct: 265 LEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS 324 Query: 62 QN---LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 ++ L+ L D + S +++ E + D ++ ++E E+L KL+ +D E Sbjct: 325 KDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEI 384 Query: 119 K 119 K Sbjct: 385 K 385
>gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related-protein 2 (U2(RNU2) small nuclear RNA auxillary factor 1-like 2) Length = 482 Score = 33.1 bits (74), Expect = 0.19 Identities = 24/96 (25%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM-- 60 ++E QL+E K + E R +EE + + + +E+ E A+ R +E + +++ Sbjct: 53 IEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE 112 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 96 +Q K + E+K +K++ E K+L E E Sbjct: 113 EQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELE 148
>gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135) Length = 1278 Score = 33.1 bits (74), Expect = 0.19 Identities = 69/329 (20%), Positives = 130/329 (39%), Gaps = 40/329 (12%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E +IQL++ + + + ++ R+L E +E E E++ + +E Sbjct: 248 LEKHKIQLEQVQEWKSKMQEQQADLQRRL------KEARKEAKEALEAKERYMEEMADTA 301 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD---LE 117 D D E + E + ++E++ L +++ E T E L A++E+ D Sbjct: 302 DAIEMATLDKEMAEERAESL-QQEVEALKERVDELTTDLEI---LKAEIEEKGSDGAASS 357 Query: 118 YKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKG----RFDGPEA 173 Y+LK +E+N L L+ + ++SS Q + + + +N+ R Sbjct: 358 YQLKQLEEQN----ARLKDALVRMRDLSSSEKQ-EHVKLQKLMEKKNQELEVVRQQRERL 412 Query: 174 QEEACSGERTYQEL------LVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEV 227 QEE E T EL + +V+ L R L NL + K ++LR V ++ Sbjct: 413 QEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNL--NLEE------KVRELRETVGDL 464 Query: 228 QKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKRE 287 + ++ E L + E L + RVR + A + + +K R+ Sbjct: 465 EAMNEMNDELQENARETELELREQL--DMAGARVREAQKRVEAAQETVADYQQTIKKYRQ 522 Query: 288 --ASLSPETKRSSSQPRGPVRTHFPFPPK 314 A L + ++Q V PP+ Sbjct: 523 LTAHLQDVNRELTNQQEASVERQQQPPPE 551
Score = 33.1 bits (74), Expect = 0.19 Identities = 33/127 (25%), Positives = 66/127 (51%), Gaps = 13/127 (10%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 +L+ ++LK A+ A K +E+ + + +E + E ++++ E Q+ D Q RL + Sbjct: 230 KLETLRLKRAEDKA-----KLKELEKHKIQLE---QVQEWKSKMQE---QQADLQRRLKE 278 Query: 62 --QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 + K +A+E+Y ++ + I++ T + AE RAE ++ V L++ D+L Sbjct: 279 ARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 338 Query: 120 LKCNKEE 126 L+ K E Sbjct: 339 LEILKAE 345
Score = 30.0 bits (66), Expect = 1.6 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 22/121 (18%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECT----EERAELAESRCQETDEQ 56 +E +E +KE K + + E +L ++E L+ +ER E ++R +ET Sbjct: 945 LEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQAL 1004 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAET-RAEFTERLVAKLEKTTDD 115 +R +KE +EE + L + + E +AE +RL ++ ++T + Sbjct: 1005 LR-----------------KKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEG 1047 Query: 116 L 116 L Sbjct: 1048 L 1048
>gi|23396825|sp|Q9BRQ0|PYG2_HUMAN Pygopus homolog 2 Length = 406 Score = 33.1 bits (74), Expect = 0.19 Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 6/53 (11%) Query: 272 PQEPSKLGDAGRKKREASL---SPETKRSSSQPRGPVRTH---FPFPPKPPTD 318 P P GRK+ +A L SPE KR S +GP +H F PP P D Sbjct: 18 PAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPPTPMVD 70
>gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein-170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament associated protein) Length = 1427 Score = 33.1 bits (74), Expect = 0.19 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 11/138 (7%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 Q+ K+ + +E +RK ++ +K+ + + R E A S + E+I QN Sbjct: 979 QQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL---QN 1035 Query: 64 L-KCLSDAEEKYSQKEDIYE------EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 L K L D E+K + EE++ DK K A+T AE +++ ++ K + Sbjct: 1036 LQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT-AEDAMQIMEQMTKEKTET 1094 Query: 117 EYKLKCNKEENLCTQRML 134 L+ K+ N Q L Sbjct: 1095 LASLEDTKQTNAKLQNEL 1112
Score = 31.6 bits (70), Expect = 0.56 Identities = 28/123 (22%), Positives = 52/123 (42%), Gaps = 23/123 (18%) Query: 28 KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS-DAEEKYSQKEDIYEEEIK 86 +L + +L E E + + + +E + ++++ ++ AE+ + +EEE K Sbjct: 932 QLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKK 991 Query: 87 ILTDKLKEAETRAEFT----------------------ERLVAKLEKTTDDLEYKLKCNK 124 L KL + E + E + E ++ L+KT D E KLK + Sbjct: 992 ELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAR 1051 Query: 125 EEN 127 EEN Sbjct: 1052 EEN 1054
Score = 29.6 bits (65), Expect = 2.1 Identities = 21/111 (18%), Positives = 57/111 (51%), Gaps = 1/111 (0%) Query: 17 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQ 76 E D + E++ + +E D+ + + S+ + ++++RL +++++ L K ++ Sbjct: 900 EKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANE 959 Query: 77 KEDIYEEEIKILTDKLKEAETR-AEFTERLVAKLEKTTDDLEYKLKCNKEE 126 ++ I+ +T K ++++ A+ E +LE+ DLE K++ + + Sbjct: 960 NASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1010
>gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4) Length = 420 Score = 33.1 bits (74), Expect = 0.19 Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 22/137 (16%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E++E +L+ +H+ E D + +LV +E L+ TE++ L + D+Q Sbjct: 288 VEMEEERLRMREHVMNEVDTNKD----RLVTLEEFLKATEKKEFLEPDSWETLDQQQFFT 343 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE-YK 119 ++ LK +Y + E E+K D+L++ + +L++ D LE K Sbjct: 344 EEELK-------EYENIIALQENELKKKADELQKQK----------EELQRQHDQLEAQK 386 Query: 120 LKCNKEENLCTQRMLYQ 136 L+ ++ Q+ L Q Sbjct: 387 LEYHQVIQQMEQKKLQQ 403
>gi|13626143|sp|O75973|C1RF_HUMAN C1q-related factor precursor (Complement component 1 Q subcomponent-like 1) Length = 258 Score = 33.1 bits (74), Expect = 0.19 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 2/72 (2%) Query: 280 DAGRKKREASLSPETKRSSSQPRG-PVRTHFPFPPKPPTDAGRETLRPKMGSEREPGK-S 337 D G E S +P P+G P RT P PP PP D G G + EPGK Sbjct: 47 DGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPG 106 Query: 338 PDAAPFPPRTGA 349 P P +GA Sbjct: 107 PPGLPGAGGSGA 118
>gi|115313|sp|P20908|CA15_HUMAN Collagen alpha 1(V) chain precursor Length = 1838 Score = 33.1 bits (74), Expect = 0.19 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 277 KLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPG- 335 K G G + P +R + P+GP T FP P PP G++ L G E G Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGP--TGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986 Query: 336 KSPDAAPFPP 345 + P PP Sbjct: 987 QGKTGPPGPP 996
Score = 30.8 bits (68), Expect = 0.95 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 274 EPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPK-PPTDAGRETLRPKMGSER 332 EP + G+ G R P+ +R GP P PK PP D G + +G Sbjct: 1286 EPGEAGEPGPSGRSGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345 Query: 333 EPGKSPDAAP 342 +PG + P Sbjct: 1346 DPGPPGEPGP 1355
Score = 30.4 bits (67), Expect = 1.2 Identities = 22/78 (28%), Positives = 29/78 (37%), Gaps = 6/78 (7%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPV----RTHFPFPPKPPTDAGRETLRPK 327 P E + GD G + S P+ ++ + P GP+ P PP P G Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGP 1553 Query: 328 MGSEREPGKSPDAAPFPP 345 G PG P P PP Sbjct: 1554 RGEAGHPG--PPGPPGPP 1569
Score = 29.3 bits (64), Expect = 2.8 Identities = 21/76 (27%), Positives = 29/76 (38%), Gaps = 6/76 (7%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPV-----RTHFPFPPKPPTDA 319 P P P + G+ G + + P P G R H P PP PP + Sbjct: 968 PPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH-PGPPGPPGEQ 1026 Query: 320 GRETLRPKMGSEREPG 335 G L K G++ +PG Sbjct: 1027 GLPGLAGKEGTKGDPG 1042
>gi|55977767|sp|P08670|VIME_HUMAN Vimentin Length = 466 Score = 32.7 bits (73), Expect = 0.25 Identities = 36/159 (22%), Positives = 75/159 (47%), Gaps = 15/159 (9%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +ELQE+ + A +I + ++ E K+++ E + + ++ L + +E E R + Sbjct: 105 VELQELNDRFANYIDKV---RFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQV 161 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD------ 114 DQ L++ + + + D E+I L +KL+E + E E + + D Sbjct: 162 DQ----LTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASLAR 217 Query: 115 -DLEYKLKCNKEENLCTQRMLYQTLLDLN-EISSVSIQI 151 DLE K++ +EE +++ + + +L +I +QI Sbjct: 218 LDLERKVESLQEEIAFLKKLHEEEIQELQAQIQEQHVQI 256
>gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) Length = 793 Score = 32.7 bits (73), Expect = 0.25 Identities = 27/129 (20%), Positives = 59/129 (45%), Gaps = 3/129 (2%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E + + +E + + EE R EE R I E + EER + E + +E+ R+ + Sbjct: 305 ERERREAEERERMREEEKRAAEERQR---IKEEEKRAAEERQRIKEEEKRAAEERQRIKE 361 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + + + + +++E+ + E + +L+E + + T+ K+E+ + K Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKRAMQETKIKGEKVEQKIEGKWVNEK 421 Query: 122 CNKEENLCT 130 +E+ L T Sbjct: 422 KAQEDKLQT 430
>gi|1168617|sp|P46379|BAT3_HUMAN Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (G3) Length = 1132 Score = 32.7 bits (73), Expect = 0.25 Identities = 29/99 (29%), Positives = 42/99 (42%), Gaps = 18/99 (18%) Query: 252 LGPEALFGRVRWRPGAAQTAPQEPSKLGDAGR-----KKREASLSPETKRSSSQPRGPVR 306 +GP+A+ VR Q P+EP ++ A R ++ AS +P T + RGP Sbjct: 931 VGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGP-- 988 Query: 307 THFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 PP P + G + +E EP AA PP Sbjct: 989 -----PPAP--EGGSRDEQDGASAETEPW----AAAVPP 1016
Score = 28.5 bits (62), Expect = 4.7 Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 22/85 (25%) Query: 264 RPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRET 323 +P +Q PQ P+ ++PE SSQ PV + P P+ P +A Sbjct: 196 QPQHSQPPPQPPA-------------VTPEPVALSSQTSEPVESEAP--PREPMEAEEV- 239 Query: 324 LRPKMGSEREPGKSPDAAPFPPRTG 348 ER P ++P+ P P G Sbjct: 240 ------EERAPAQNPELTPGPAPAG 258
>gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precursor (Laminin B1 chain) Length = 1786 Score = 32.7 bits (73), Expect = 0.25 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 19/142 (13%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E+ L+EAK ++ A +V +++ LE E+ AE ++ DE I+ QNL Sbjct: 1572 EMLLEEAKRASKSAT----DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQ-GTQNL 1626 Query: 65 KCLSDAEE--------KYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 ++E SQ+ E ++ L K + AE+ E++V ++++ +D+ Sbjct: 1627 LTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686 Query: 117 EYKL------KCNKEENLCTQR 132 + L K K ENL ++ Sbjct: 1687 KKTLDGELDEKYKKVENLIAKK 1708
>gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) Length = 2567 Score = 32.7 bits (73), Expect = 0.25 Identities = 65/334 (19%), Positives = 124/334 (37%), Gaps = 35/334 (10%) Query: 28 KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKI 87 K + + +LE + E +E++C+E + +++ +L+ + E ++ + + +E++ Sbjct: 1825 KTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYR 1884 Query: 88 L----TDKLKEAETRAEFTERLVAK-----LEKTTD-----DLEYKLKCNKEE--NLCTQ 131 L D LK + + L+ K + D +L+ +L+ K+E L Q Sbjct: 1885 LQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQ 1944 Query: 132 RMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQ 191 + Q ++ E S+V I + CD +NK F + + R L+ Sbjct: 1945 LQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMG 2004 Query: 192 NPIVQPLAS------------RRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIM 239 + Q S RRL + ++ + R E++K+V + Sbjct: 2005 EELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQ 2064 Query: 240 VLAED-TLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSS 298 L D I + +A V ++ Q G +GRK+ + S Sbjct: 2065 TLQTDLETSIRRIADLQAALEEVASSDSDTESV-QTAVDCGSSGRKEMD-----NVSILS 2118 Query: 299 SQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSER 332 SQP G +++ TD R R S R Sbjct: 2119 SQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSR 2152
Score = 28.5 bits (62), Expect = 4.7 Identities = 47/230 (20%), Positives = 97/230 (42%), Gaps = 25/230 (10%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E + + +A +E K+E+V +KL GD+ + +E ++I+L Sbjct: 1460 LESERAERLQAFREVQELKSKHEQVQKKL----GDV----------NKQLEEAQQKIQLN 1505 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 D A+E + + D + E + L +L++ E R + +LE+ +L+ Sbjct: 1506 DLERNPTGGADE-WQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAY 1564 Query: 121 KCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSG 180 K+ +R + DL + + + N R ++ + +FD AQ G Sbjct: 1565 DGAKKMAHQLKRKCHHLTCDLED---TCVLLENQQSRNHELEKKQKKFDLQLAQ---ALG 1618 Query: 181 ERTYQELLVNQNPIVQPLASRR--LTRNLYKCIKKAMKQKQLRRGVKEVQ 228 E +++ L + + Q S R L + + +K + QL++ V+ +Q Sbjct: 1619 ESVFEKGL--REKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQ 1666
>gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150) Length = 938 Score = 32.3 bits (72), Expect = 0.33 Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 9/101 (8%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E +E +EAK EEA +K EE E +L+ +ER E E +E E+ RL + Sbjct: 337 EEKEKLKEEAKRAKEEAKKKKEE--------EKELK-EKERREKREKDEKEKAEKQRLKE 387 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFT 102 + K +A E +++ EEE ++ ++ + +AE T Sbjct: 388 ERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 428
>gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (HuGBP-1) Length = 592 Score = 32.3 bits (72), Expect = 0.33 Identities = 33/154 (21%), Positives = 65/154 (42%), Gaps = 29/154 (18%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL----------- 64 ++ +KY E PRK + E L+ + E +TD+ + ++ + Sbjct: 441 QDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQ 500 Query: 65 ---KCLSDAEEK----YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 K L + + K QKE Y+E +K LT+K++ +L+ + E+T Sbjct: 501 ASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV------QLLKEQERT----- 549 Query: 118 YKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQI 151 LK ++E L + ++ + NEI + ++ Sbjct: 550 LALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKM 583
>gi|1703310|sp|Q01484|ANK2_HUMAN Ankyrin 2 (Brain ankyrin) (Ankyrin B) (Ankyrin, nonerythroid) Length = 3924 Score = 32.3 bits (72), Expect = 0.33 Identities = 79/383 (20%), Positives = 139/383 (36%), Gaps = 58/383 (15%) Query: 6 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELA-----ESRCQETDEQIRLM 60 I++KE AEE + E+ + ++ DLE E ES Q + + L+ Sbjct: 1499 IKVKELVKAAEEEPGEPFEIVER---VKEDLEKVNEILRSGTCTRDESSVQSSRSERGLV 1555 Query: 61 DQNLKCLSDAE-EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 119 ++ +SD E E+ QK + E + ++ + E + + + + TDDL Sbjct: 1556 EEEWVIVSDEEIEEARQKAPLEITEYPCVEVRI-DKEIKGKVEKDSTGLVNYLTDDLNTC 1614 Query: 120 LKCNKE-------------ENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGC------- 159 + KE E L R + D+ + S Q + G Sbjct: 1615 VPLPKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRK 1674 Query: 160 CDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIV--QPLASRRLTRNLYKCIKKAMKQ 217 ++ K + +G +A E ++ E + ++P + +PL + + T L + Sbjct: 1675 LKEKQKQKEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIE----ETPI 1730 Query: 218 KQLRRGVKEVQKFVNKGEKG-----IMVLAEDTLPIEEVLGPEALFG----RVRWRPGAA 268 ++ VK +QK V +KG I V ++ +P + P R PG+ Sbjct: 1731 GSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSP 1790 Query: 269 QTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGP---VRTHFP----------FPPKP 315 + S L + + +R +SP +K P P H P P P Sbjct: 1791 SPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSP 1850 Query: 316 PTDAGRETLRPKMGSEREPGKSP 338 T R + +ER P SP Sbjct: 1851 STKTERHSPVSSTKTERHPPVSP 1873
Score = 28.9 bits (63), Expect = 3.6 Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 3/76 (3%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRT--HFPFPPKPPTDAGRE 322 P + + S + + ++ + +SP TK P +T H P P TD R Sbjct: 1823 PVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDK-RP 1881 Query: 323 TLRPKMGSEREPGKSP 338 + P +E+ P SP Sbjct: 1882 PVSPSGRTEKHPPVSP 1897
>gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 32.3 bits (72), Expect = 0.33 Identities = 32/165 (19%), Positives = 67/165 (40%), Gaps = 16/165 (9%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 EE DR+ +E + +++I+ L + + S+ ++ L+D +++ Sbjct: 498 EELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQD-------------LNDEKKRVH 544 Query: 76 QKEDI---YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 132 Q ED +E+ + +KL ++E KLE ++L +L ++E N+ Q+ Sbjct: 545 QLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQK 604 Query: 133 MLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEA 177 + + + +I N + D N D + EA Sbjct: 605 ENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREA 649
>gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like protein) Length = 180 Score = 32.0 bits (71), Expect = 0.43 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEK 73 ++ D EE+ ++L E + E + +LAE R E + + +++N AEEK Sbjct: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 Query: 74 YSQK----EDIYEEEIKILTDKLKEAETRAEFTER 104 + K ++I E + L ++L+E E A R Sbjct: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRR 170
>gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (Histidine--tRNA ligase) (HisRS) Length = 509 Score = 32.0 bits (71), Expect = 0.43 Identities = 18/64 (28%), Positives = 34/64 (53%) Query: 25 VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE 84 V R I+E LE EE+ E++ Q +L+++ LK +S+ + + E +Y++ Sbjct: 386 VERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKN 445 Query: 85 IKIL 88 K+L Sbjct: 446 PKLL 449
>gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase gamma subunit) (IkB kinase gamma subunit) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3) Length = 419 Score = 32.0 bits (71), Expect = 0.43 Identities = 18/95 (18%), Positives = 44/95 (46%), Gaps = 3/95 (3%) Query: 4 QEIQLKEAKHIAEEADRKYEE---VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E L+E +H+ + E+ V ++ + G+L+ ++ R E A CQ + + R Sbjct: 118 KEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAA 177 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 95 + + L E Q+ + +++++ ++ A Sbjct: 178 SEQARQLESEREALQQQHSVQVDQLRMQGQSVEAA 212
>gi|59800456|sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (WAVE-2 protein) (Verprolin homology domain-containing protein 2) Length = 498 Score = 32.0 bits (71), Expect = 0.43 Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 291 SPETKRSSSQPRGPVRTHF--PFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 SP T S P P F P PP PP A TL P S+ G P P PP Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP 399
>gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine receptor protein, beta-3 chain precursor Length = 458 Score = 32.0 bits (71), Expect = 0.43 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 5/71 (7%) Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTER---LVAKLEKTTDDLEYKL 120 L C+ D ++YS E EE ++ K+ E + + + ++ LVA LEK D + Y Sbjct: 346 LLCMKDHVDRYSSPEK--EESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYIS 403 Query: 121 KCNKEENLCTQ 131 + K+E+ +Q Sbjct: 404 RHVKKEHFISQ 414
>gi|34223720|sp|P25940|CA35_HUMAN Collagen alpha 3(V) chain precursor Length = 1745 Score = 32.0 bits (71), Expect = 0.43 Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 265 PGAAQT--APQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPK-PPTDAGR 321 PGA+ AP P K G +G RE + + P GP P + PP G Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356 Query: 322 ETLRPKMGSEREPG 335 E LR G EPG Sbjct: 1357 EGLRGIPGPVGEPG 1370
>gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crosslinking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin 1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620) Length = 5430 Score = 32.0 bits (71), Expect = 0.43 Identities = 35/182 (19%), Positives = 77/182 (42%), Gaps = 7/182 (3%) Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 + L Q++K +SDA + ++E + EEE + +K+KE + L + Sbjct: 1396 VTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKEL---LGWVSTLARNTQGKATSS 1452 Query: 117 EYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEE 176 E K + E+ + Q++L + L E S +I+ S + + E+ Sbjct: 1453 ETKESTDIEKAILEQQVLSEELTTKKEQVSEAIKTSQIFL--AKHGHKLSEKEKKQISEQ 1510 Query: 177 ACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEK 236 + + Y +L +Q L S+ + K ++K +Q + ++++ +V + E+ Sbjct: 1511 LNALNKAYHDLCDGSANQLQQLQSQLAHQTEQKTLQK--QQNTCHQQLEDLCSWVGQAER 1568 Query: 237 GI 238 + Sbjct: 1569 AL 1570
>gi|42559826|sp|Q8IWN7|RP1L1_HUMAN Retinitis pigmentosa 1-like 1 protein Length = 2480 Score = 32.0 bits (71), Expect = 0.43 Identities = 42/187 (22%), Positives = 71/187 (37%), Gaps = 30/187 (16%) Query: 10 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 69 EA +EA + E V E + E A+ AE QE + Q + + ++ Sbjct: 1987 EAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEEAQEAEGQAQPESEVIESQEA 2046 Query: 70 AEEKYSQKEDIYEEEIKILTDKLK-EAETRAEFTERLVAKLEKT---------TDDLEYK 119 EE + ED+ E+++ T + + EA+ +E E A+ E +D +E + Sbjct: 2047 EEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQ 2106 Query: 120 LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACS 179 K EE + ++ G ++ G + PEA+EEA Sbjct: 2107 PKSEGEE-------------------AQEVEGETQKTEGDAQPESDG-VEAPEAEEEAQE 2146 Query: 180 GERTYQE 186 E QE Sbjct: 2147 AEGEVQE 2153
>gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 Length = 1539 Score = 31.6 bits (70), Expect = 0.56 Identities = 39/169 (23%), Positives = 76/169 (44%), Gaps = 22/169 (13%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEG-DLECTEERAELAESR--CQETDEQI 57 +E++E+ ++ AE + YE + L +E + E + AEL + Q+ ++ + Sbjct: 122 LEMKELNERQR---AEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQML 178 Query: 58 R--LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 R L D K +SDA+ + + + E E+K+ KL+E A ++ +++ D Sbjct: 179 RDELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRD- 237 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEI------SSVSIQISNYSFRG 158 + E+L Q + YQ D + +VS+Q+S + G Sbjct: 238 -------KEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALG 279
Score = 30.4 bits (67), Expect = 1.2 Identities = 21/94 (22%), Positives = 48/94 (51%), Gaps = 6/94 (6%) Query: 40 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 99 E + + E+ + ++ I + Q +K ++ E+K ++ + E++IKIL + AET Sbjct: 1336 ETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQ 1395 Query: 100 EFTERLVA------KLEKTTDDLEYKLKCNKEEN 127 L +L+K +L ++++ NK+++ Sbjct: 1396 GLKRELQVLRLANHQLDKEKAELIHQIEANKDQS 1429
>gi|27734440|sp|Q96RN5|PCQAP_HUMAN Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene-1) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) Length = 788 Score = 31.6 bits (70), Expect = 0.56 Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 6/129 (4%) Query: 215 MKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQE 274 ++Q ++ V++ Q V + MV A I E L + R R+ P A +A Sbjct: 354 VQQPPVQPQVQQQQTAVQTAQAAQMV-APGVQMITEALAQGGMHIRARFPPTTAVSAI-- 410 Query: 275 PSKLGDAGRKKR-EASLSPETKRSSSQPRGPVRT--HFPFPPKPPTDAGRETLRPKMGSE 331 PS GR+ + S S SS P V+T P PP+P G+ + +P Sbjct: 411 PSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS 470 Query: 332 REPGKSPDA 340 P SP + Sbjct: 471 SGPAPSPSS 479
>gi|51338841|sp|Q9Y3L3|3BP1_HUMAN SH3-domain binding protein 1 (3BP-1) Length = 701 Score = 31.6 bits (70), Expect = 0.56 Identities = 27/90 (30%), Positives = 30/90 (33%), Gaps = 12/90 (13%) Query: 267 AAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRP 326 A AP L A K+R S P S R P P P D R T RP Sbjct: 514 APAPAPAPAPALASAATKERTESEVPPRPASPKVTRSP-----PETAAPVEDMARRTKRP 568 Query: 327 KMGSEREP-------GKSPDAAPFPPRTGA 349 P SP A P PP +G+ Sbjct: 569 APARPTMPPPQVSGSRSSPPAPPLPPGSGS 598
>gi|13431960|sp|O00401|WASL_HUMAN Neural Wiskott-Aldrich syndrome protein (N-WASP) Length = 505 Score = 31.6 bits (70), Expect = 0.56 Identities = 19/55 (34%), Positives = 25/55 (45%), Gaps = 2/55 (3%) Query: 293 ETKRSSSQPRGPVRTHFPFPPKPPTDAG--RETLRPKMGSEREPGKSPDAAPFPP 345 E +R + P P R P PP PP +G R + P ++P AAP PP Sbjct: 271 ELRRQAPPPPPPSRGGPPPPPPPPHSSGPPPPPARGRGAPPPPPSRAPTAAPPPP 325
>gi|118685|sp|P11532|DMD_HUMAN Dystrophin Length = 3685 Score = 31.6 bits (70), Expect = 0.56 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%) Query: 5 EIQLKEAK----HIAEEADRKYEEVP---RKLVIIEGDLECTEERAELAESRCQETDEQI 57 E +LKE H+ ++ + E + K V ++ DL E AE E D + Sbjct: 1128 ETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEY 1187 Query: 58 RLMDQNLKCLSD---AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 + D+ K + + A+E+ QKE ++K+LT+ + +A + K E T Sbjct: 1188 KTPDELQKAVEEMKRAKEEAQQKE----AKVKLLTESVNSVIAQAPPVAQEALKKELETL 1243 Query: 115 DLEYKLKCNKEENLC 129 Y+ C + C Sbjct: 1244 TTNYQWLCTRLNGKC 1258
>gi|21542396|sp|P12107|CA1B_HUMAN Collagen alpha 1(XI) chain precursor Length = 1806 Score = 31.6 bits (70), Expect = 0.56 Identities = 23/81 (28%), Positives = 30/81 (37%), Gaps = 2/81 (2%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETL 324 P ++ A K G G + P +R P+GPV FP P PP G++ L Sbjct: 887 PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG--FPGPKGPPGPPGKDGL 944 Query: 325 RPKMGSEREPGKSPDAAPFPP 345 G E G P P Sbjct: 945 PGHPGQRGETGFQGKTGPPGP 965
Score = 30.4 bits (67), Expect = 1.2 Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 11/96 (11%) Query: 253 GPEALFGRVRWRPGA--AQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFP 310 GP G+ R RPGA + P EP GD G + R P+GP Sbjct: 571 GPTGKPGK-RGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP------ 623 Query: 311 FPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPR 346 P PP D G ++G PG++ PR Sbjct: 624 --PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
Score = 27.7 bits (60), Expect = 8.1 Identities = 18/75 (24%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPV----RTHFPFPPKPPTDAG 320 P P P + G+ G + + P P G +P PP PP + G Sbjct: 938 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGYPGPPGPPGEQG 997 Query: 321 RETLRPKMGSEREPG 335 K G++ +PG Sbjct: 998 LPGAAGKEGAKGDPG 1012
>gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related-protein 1 (U2(RNU2) small nuclear RNA auxillary factor 1-like 1) Length = 479 Score = 31.2 bits (69), Expect = 0.73 Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR--LM 60 ++E QL+E K + E +R +EE + + + +E+ E A+ +E + +++ Sbjct: 58 IEEQQLEEEKLLERERERLHEEWLLREQKAQEEFRIKKEKEEAAKKWLEEQERKLKEQWK 117 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 96 +Q K + E+K +K++ E K+L + E Sbjct: 118 EQQRKEREEEEQKQQEKKEKEEAVQKMLDQAENDLE 153
Score = 29.3 bits (64), Expect = 2.8 Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 11/101 (10%) Query: 26 PRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEI 85 P+K+ E A E R + E RL D L ++ED + EE Sbjct: 10 PKKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLS--------QEEEEDTFIEEQ 61 Query: 86 KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 ++ +KL E E R E + + +K + E+++K KEE Sbjct: 62 QLEEEKLLERE-RERLHEEWLLREQKAQE--EFRIKKEKEE 99
>gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) Length = 450 Score = 31.2 bits (69), Expect = 0.73 Identities = 25/119 (21%), Positives = 54/119 (45%), Gaps = 10/119 (8%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 + + E + + K E ++ E+ +L + +L EER ++ ++ +++ Sbjct: 152 LNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLI---QELEDVEKNRKIV 208 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIK-------ILTDKLKEAETRAEFTERLVAKLEKT 112 +NL+ + E+ Q+E Y+ E L D+LK E + + + + KL+KT Sbjct: 209 AENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
>gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing extension spike protein) Length = 577 Score = 31.2 bits (69), Expect = 0.73 Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 8/116 (6%) Query: 1 MELQEI--QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR 58 +E+Q++ Q +E KH + E +K + E + E E E R ++ +EQ + Sbjct: 300 IEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTK 359 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 Q L EE+ + ++ +E + ++ K A+ R E E A L+ + D Sbjct: 360 KAQQEL------EEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRD 409
>gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-associated protein expressed in ventricle 1 (CDV-1 protein) Length = 676 Score = 31.2 bits (69), Expect = 0.73 Identities = 25/129 (19%), Positives = 59/129 (45%), Gaps = 11/129 (8%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E+ E++ + ++E + Y V K + ++ + + + QE DE+ D Sbjct: 474 EVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYD 533 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE----KTTDDLE 117 C + E S+ E+E++ L ++ + E+R +T ++ LE + TD+++ Sbjct: 534 S---CAAGLESNRSK----LEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK 586 Query: 118 YKLKCNKEE 126 + +++E Sbjct: 587 AYISSDQQE 595
>gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein Length = 919 Score = 31.2 bits (69), Expect = 0.73 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 6/124 (4%) Query: 16 EEADRKYEEVPRKLVIIEGD-LECTEERAELAESRCQE-----TDEQIRLMDQNLKCLSD 69 EE +R+++E+ +K E + L E LAE R QE EQ R + + Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 709 Query: 70 AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLC 129 +E+ Q+ + E+E + ++L+ E + L + E+ +LE K K +++ L Sbjct: 710 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 769 Query: 130 TQRM 133 +++ Sbjct: 770 ERQL 773
>gi|50400978|sp|Q7Z5J4|RAI1_HUMAN Retinoic acid induced protein 1 Length = 1906 Score = 31.2 bits (69), Expect = 0.73 Identities = 75/348 (21%), Positives = 128/348 (36%), Gaps = 49/348 (14%) Query: 23 EEVP--RKLVIIEGDLECTEERAELAES----RCQETDEQIRLMDQNLKCLSDAE----- 71 EE P K+ + GD + E E+ +C E + R ++ + C S A+ Sbjct: 795 EEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWLEDSRHCCSTADFGDLP 854 Query: 72 --EKYSQKEDIY-EEEIKILTDKLKEAETRAEFTERLVAK--LEKTTDDLEYKLKCNKEE 126 S+KED+ EEE L + L E R + L K L T +++E L +K Sbjct: 855 LLPPTSRKEDLEAEEEYSSLCELLGSPEQRPGMQDPLSPKAPLICTKEEVEEVLD-SKAG 913 Query: 127 NLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQE 186 + ++++ L ++ ++ F G +GP+ E G+ T + Sbjct: 914 WGSPCHLSGESVILLGPTVGTESKVQSW-FESSLSHMKPGE-EGPDG--ERAPGDSTTSD 969 Query: 187 LLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTL 246 + Q P + + + K+++ +++ RG+ E + + VL +D L Sbjct: 970 ASLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRVHRGLPEAEDSPCRAP----VLPKDLL 1025 Query: 247 PIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREAS-----LSPETKRSSSQP 301 E GP PQ ++ AG R AS + + + S+P Sbjct: 1026 LPESCTGP-----------------PQ--GQMEGAGAPGRGASEGLPRMCTRSLTALSEP 1066 Query: 302 RGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTGA 349 R P P PP G + +R SP AA P A Sbjct: 1067 RTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAASSPSNPAA 1114
>gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat protein 19 (TPR repeat protein 19) Length = 380 Score = 31.2 bits (69), Expect = 0.73 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 17/130 (13%) Query: 7 QLKEAKHIAEEADRKYEEV-----PRKLVIIEG-----DLECTEERAELAESRCQETDEQ 56 Q +A+ + E+A + EE+ P+ +V++ D + + A + R + Q Sbjct: 252 QPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ 311 Query: 57 IR-----LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 111 I ++ NL + E+Y+Q ++IY+E +K KLK+ E + +A+L K Sbjct: 312 INHPELHMVLSNLAAVLMHRERYTQAKEIYQEALK--QAKLKKDEISVQHIREELAELSK 369 Query: 112 TTDDLEYKLK 121 + L +K Sbjct: 370 KSRPLTNSVK 379
>gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) Length = 2090 Score = 31.2 bits (69), Expect = 0.73 Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 14/151 (9%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL--M 60 + E++L++ K +E RK +E LV + L E+ EL + D QI M Sbjct: 1451 IAELELEKTK--LQELTRKLKERVTILVKQKDVLSHGEKEEEL---KAMMHDLQITCSEM 1505 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 Q ++ L EK Q+ I EI L ++ + + + L + +++ K Sbjct: 1506 QQKVELLRYESEKLQQENSILRNEITTLNEEDSISNLK-------LGTLNGSQEEMWQKT 1558 Query: 121 KCNKEENLCTQRMLYQTLLDLNEISSVSIQI 151 + K+EN Q+M+ ++E+ + Q+ Sbjct: 1559 ETVKQENAAVQKMVENLKKQISELKIKNQQL 1589
>gi|12643900|sp|Q9UMN6|MLL4_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2) Length = 2715 Score = 30.8 bits (68), Expect = 0.95 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 6/88 (6%) Query: 266 GAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLR 325 G + +P K + R+ + + RSS + P R PPKPP LR Sbjct: 505 GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLR 564 Query: 326 PKMGS------EREPGKSPDAAPFPPRT 347 P + + E P SP AP PP T Sbjct: 565 PPITTSPPVPQEPAPVPSPPRAPTPPST 592
>gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precursor (Laminin A chain) Length = 3075 Score = 30.8 bits (68), Expect = 0.95 Identities = 22/122 (18%), Positives = 55/122 (45%), Gaps = 11/122 (9%) Query: 6 IQLKEAKHIAEEADRKYEEVPRKLVIIE-----------GDLECTEERAELAESRCQETD 54 ++LK A+ + + Y++ +L +++ +L+ E AE++ QE++ Sbjct: 1720 LELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESN 1779 Query: 55 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 + +++ NL+ SD + +++++ E I + A + + + + LE D Sbjct: 1780 HLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQD 1839 Query: 115 DL 116 L Sbjct: 1840 KL 1841
>gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi complex component 7 Length = 770 Score = 30.8 bits (68), Expect = 0.95 Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 34/167 (20%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL-------- 59 LKE + +E +K+E+ + + + +++ + R +LA QE D+ L Sbjct: 83 LKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETF 142 Query: 60 --------------MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL 105 M +L L D + YS+K ++ E +K + L + A FT + Sbjct: 143 KTQDIAVISAKLTGMQNSLMMLVDTPD-YSEK-CVHLEALKNRLEALASPQIVAAFTSQA 200 Query: 106 V----------AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 142 V ++++ L Y KC+K + L + L Q+ L L+ Sbjct: 201 VDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLSLD 247
>gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding protein 2 (RBBP-2) Length = 1722 Score = 30.8 bits (68), Expect = 0.95 Identities = 26/90 (28%), Positives = 43/90 (47%), Gaps = 11/90 (12%) Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK---TTDDLEYKLKCN 123 L DAE++ + D++ + L D +KEAET A + L++K +K + D + K Sbjct: 767 LEDAEDRKYPENDLFRK----LRDAVKEAETCASVAQLLLSKKQKHRQSPDSGRTRTKLT 822 Query: 124 KEENLCTQRMLYQTLLDLNEISSVSIQISN 153 EE + Q L L + S + Q+ N Sbjct: 823 VEE----LKAFVQQLFSLPCVISQARQVKN 848
>gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 Length = 1020 Score = 30.8 bits (68), Expect = 0.95 Identities = 50/214 (23%), Positives = 84/214 (39%), Gaps = 31/214 (14%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ++ I + +A + +E K E K + E + EERA L S+ Q DE+ + Sbjct: 261 LKASHIGMLQATQMTQEVTIKDLE-SEKSRVNERLSQLEEERAFL-RSKTQSLDEEQK-- 316 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA-----ETRAEFTERLV--------- 106 Q L+ E +++ YE E+K L +L+E E ++ E L Sbjct: 317 QQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEA 376 Query: 107 ---------AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFR 157 KL+ ++ K K N EE+ + L Q L +L E+ + +N Sbjct: 377 VHSNAIRDKKKLQMDLEEQHNKDKLNLEED---KNQLQQELENLKEVLEDKLNTANQEI- 432 Query: 158 GCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQ 191 G D + G + E + + QE L N+ Sbjct: 433 GHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNE 466
Score = 27.7 bits (60), Expect = 8.1 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 7/125 (5%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECT-EERAELAESRCQETDEQIRLM 60 +L E K + +A + E V + + L+ EE+ + +E Q++ Sbjct: 354 QLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQE 413 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 +NLK E K + +EI L D ++++E E L+A L+ + + L+ +L Sbjct: 414 LENLK------EVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNEL 467 Query: 121 KCNKE 125 K+ Sbjct: 468 DLTKD 472
>gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled-coil domain protein 3 Length = 939 Score = 30.8 bits (68), Expect = 0.95 Identities = 44/242 (18%), Positives = 99/242 (40%), Gaps = 34/242 (14%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE---QIR 58 E+ + +K+ + + +E D V VI+ +E + E E+ + D+ Q++ Sbjct: 643 EVPSLVVKKEETVEDEID-----VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQ 697 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 + L +++ +E Y ++ ++ ++IK+L ++ E + E + T D + Sbjct: 698 ELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILEMNDKYVKKETC---HQSTETDAVF 754 Query: 119 KLKCNKEENLCTQRMLYQTLLDLNEISSVSIQIS-----NYSFRGCCDDQNKGRFDGPEA 173 L+ ++ M+ Q L EI + Q S C ++++K D Sbjct: 755 LLESINGKSESPDHMVSQYQQALEEIERLKKQCSALQHVKAECSQCSNNESKSEMD---- 810 Query: 174 QEEACSGERTYQELLVNQNPIVQPLASRRLTRNLYKCIKK--AMKQKQLRRGVKEVQKFV 231 E+ V + + + L + R+ YK + M++ Q+R +E++ V Sbjct: 811 ------------EMAVQLDDVFRQLDKCSIERDQYKSEVELLEMEKSQIRSQCEELKTEV 858 Query: 232 NK 233 + Sbjct: 859 EQ 860
>gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET) Length = 673 Score = 30.4 bits (67), Expect = 1.2 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 7/97 (7%) Query: 28 KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEE-------KYSQKEDI 80 +L + +L+ ER + + Q+ +Q+R Q +K L K + + Sbjct: 142 QLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQ 201 Query: 81 YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 ++E+K L + E E R E LV +L+K +L+ Sbjct: 202 GQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQ 238
>gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170) Length = 1498 Score = 30.4 bits (67), Expect = 1.2 Identities = 36/141 (25%), Positives = 66/141 (46%), Gaps = 30/141 (21%) Query: 1 MELQEI--QLKEAKHIAEEADRKYEEVPRKLVIIEG--DLECTEERAELAESRCQ----- 51 +EL E+ +L+ +H+ ++ + ++ L I EG E + +AELAE+R Q Sbjct: 1214 LELSEVKKELQAKEHLVQKLQAEADD----LQIREGKHSQEIAQFQAELAEARAQLQLLQ 1269 Query: 52 -ETDEQIRLMD------QNLKCLSDAEEK----YSQKEDIYEEEIKILTDKLKEAETRAE 100 + DEQ+ +NLK D +E+ Q+ D+ E++ + KE E + Sbjct: 1270 KQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGR------KELEGLQQ 1323 Query: 101 FTERLVAKLEKTTDDLEYKLK 121 + + ++LE +DL K Sbjct: 1324 LLQNVKSELEMAQEDLSMTQK 1344
Score = 30.4 bits (67), Expect = 1.2 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 6/125 (4%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E QL++ K + D++ E + ++ + + L T+E + SR Q D D+ Sbjct: 695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQ---SREQSLDALQTHYDELQ 751 Query: 65 KCLSDAEEKYSQKED---IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 L + + + + +ED + + E IL L+ A++ E +R +LE+ T++ L+ Sbjct: 752 ARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLE 811 Query: 122 CNKEE 126 +EE Sbjct: 812 KLREE 816
Score = 29.6 bits (65), Expect = 2.1 Identities = 64/318 (20%), Positives = 119/318 (37%), Gaps = 49/318 (15%) Query: 33 EGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY--SQKEDIYEEEI----- 85 E DL + + R +E D Q++ + Q L+ + E++ S KE + ++ Sbjct: 1146 EADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHN 1205 Query: 86 ----KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 K + +L E + + E LV KL+ DDL+ + + +E + Q +L Sbjct: 1206 RRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQE-------IAQFQAEL 1258 Query: 142 NEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTYQELLVNQNPIVQPLASR 201 E + +Q+ Q G + + E ER Q L + Sbjct: 1259 AE-ARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLD--------- 1308 Query: 202 RLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRV 261 + ++Q R+ ++ +Q+ + + + + ED ++ L +V Sbjct: 1309 -------------LTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK--DKFMLQAKV 1353 Query: 262 RWRPGAAQTAPQEPSKLG-DAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKP-PTDA 319 +T Q+ +L D R + P+ + SSS P P++ P P P Sbjct: 1354 SELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATPIK----IPDCPVPASL 1409 Query: 320 GRETLRPKMGSEREPGKS 337 E LRP +EP K+ Sbjct: 1410 LEELLRPPPAVSKEPLKN 1427
>gi|115306|sp|P02461|CA13_HUMAN Collagen alpha 1(III) chain precursor Length = 1466 Score = 30.4 bits (67), Expect = 1.2 Identities = 25/81 (30%), Positives = 29/81 (35%), Gaps = 8/81 (9%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPV----RTHFPFPPKPPTDAGRETLRPK 327 P P G AG++ S P R P GP + P P PP G R Sbjct: 1115 PGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGS 1174 Query: 328 MGSEREPGK----SPDAAPFP 344 GS PG+ P AP P Sbjct: 1175 EGSPGHPGQPGPPGPPGAPGP 1195
>gi|114870|sp|P20749|BCL3_HUMAN B-cell lymphoma 3-encoded protein (Bcl-3 protein) Length = 446 Score = 30.4 bits (67), Expect = 1.2 Identities = 25/82 (30%), Positives = 32/82 (39%), Gaps = 12/82 (14%) Query: 267 AAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPT----DAGRE 322 +A T+P+ S+L G S SP + S S PR P FP PP Sbjct: 370 SANTSPESSSRLSSNGL----LSASPSSSPSQSPPRDPP----GFPMAPPNFFLPSPSPP 421 Query: 323 TLRPKMGSEREPGKSPDAAPFP 344 P G R PG+ +P P Sbjct: 422 AFLPFAGVLRGPGRPVPPSPAP 443
>gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor Length = 314 Score = 30.4 bits (67), Expect = 1.2 Identities = 26/102 (25%), Positives = 52/102 (50%), Gaps = 7/102 (6%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 +L+E Q ++A+ AEEA+R EE R E + + EER L E + +E + + R Sbjct: 124 KLEEKQARKAQREAEEAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 103 + E+Y + ++ + E + + + + E ++++ TE Sbjct: 182 AQRE-----HEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
Score = 28.5 bits (62), Expect = 4.7 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Query: 266 GAAQTAPQEP---SKLGDAGRKKREASLSPETKRSSSQPR 302 G A +A QEP +L AGR + L PE R+ +PR Sbjct: 26 GRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPR 65
>gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 Length = 670 Score = 30.4 bits (67), Expect = 1.2 Identities = 30/121 (24%), Positives = 53/121 (43%), Gaps = 21/121 (17%) Query: 3 LQEIQ-LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR----CQETDEQI 57 LQ +Q L E K++AE EE+ KL II ++ +++ + E + C+ Q+ Sbjct: 242 LQALQKLSEDKNLAER-----EELTHKLSIITTKMDANDKKIQSLEKQLRLNCRAFSRQL 296 Query: 58 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE----FTERLVAKLEKTT 113 + + A + + E+K L KLKE + E ++ R++ L T Sbjct: 297 AIETRKTLAAQTATKTL-------QVEVKHLQQKLKEKDRELEIKNIYSHRILKNLHDTE 349 Query: 114 D 114 D Sbjct: 350 D 350
>gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW-11) Length = 1583 Score = 30.4 bits (67), Expect = 1.2 Identities = 29/158 (18%), Positives = 73/158 (46%), Gaps = 16/158 (10%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 E +E + E E+ + E+ +K+ + G LE T + + + + ++ Q++++ Sbjct: 517 EREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLS 576 Query: 62 QNLKCLSDAEEKYSQKEDIYEEEIKILTDK---LKEAETRAEFTERLVAKLEKTTDDLEY 118 ++ + LS ++ + +YEE K+ ++K ++ E E ++ K T + + Sbjct: 577 EDKEVLS------AEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKL 630 Query: 119 KLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSF 156 +L +++NL LL+ ++ + ++ Y F Sbjct: 631 QLMVEEQDNL-------NKLLENEQVQKLFVKTQLYGF 661
Score = 29.3 bits (64), Expect = 2.8 Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 8/117 (6%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELA--ESRCQETDEQIR 58 EL+E+Q++ K ++ ++ ++L +++ D + T E+A E +E ++++ Sbjct: 1022 ELEELQVQLQKE-----KKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLT 1076 Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 + ++ L + QK++ +EEI L +++ E + ++L+ K +K D Sbjct: 1077 NKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1133
Score = 28.5 bits (62), Expect = 4.7 Identities = 28/109 (25%), Positives = 42/109 (38%), Gaps = 21/109 (19%) Query: 78 EDIYEEEIKILTDKLKEAETR-------AEFTERLVAKLEKTT-----------DDLEYK 119 E + E++K L D LKE E++ + L KLE +DLE+K Sbjct: 226 EQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFK 285 Query: 120 ---LKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNK 165 L KEE C L L LN+ +++ N + + K Sbjct: 286 INELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQK 334
Score = 27.7 bits (60), Expect = 8.1 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 10/117 (8%) Query: 40 EERAELAESRCQETDE---QIRLMDQNLKCLSDAEEKYSQ--KEDI--YEEEIKILTDKL 92 EE+ E E C+E +E +I+L+ K D+ K +Q KE++ E L+ + Sbjct: 849 EEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASM 908 Query: 93 KEAETRAEFTERLVAKLEKTTDDLEY-KLKCNKEENLCTQ--RMLYQTLLDLNEISS 146 ++ AE + L+ + EK ++ L+ K + N E+ R L + L I+S Sbjct: 909 RDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINS 965
>gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1 protein) Length = 976 Score = 30.4 bits (67), Expect = 1.2 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Query: 5 EIQLK-EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 E QL+ E +++ EE +K +EV KL + +EE + + ++ I + Q Sbjct: 569 ETQLRNELEYVREELKQKRDEVKCKL-------DKSEENCNNLRKQVENKNKYIEELQQE 621 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR-AEFTERLVAKLE 110 K L S++ ++YE ++ L +L+ A+ + E T+ ++E Sbjct: 622 NKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIE 669
>gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) (C-NAP1) (Centrosome protein 250) (Centrosome associated protein CEP250) Length = 2442 Score = 30.4 bits (67), Expect = 1.2 Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 9/115 (7%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 +E +++ + +E +++ E L ++ DL+ + +L + + QE ++ +++ Sbjct: 1433 REEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHL 1492 Query: 64 LKCLSDAEEKYS-QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 + + E+K + Q+E I E E K+ ET+ E + +LEK +E Sbjct: 1493 PMAVQEREQKLTVQREQIRELE--------KDRETQRNVLEHQLLELEKKDQMIE 1539
Score = 28.1 bits (61), Expect = 6.2 Identities = 23/136 (16%), Positives = 56/136 (41%), Gaps = 25/136 (18%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRK--------------LVIIEGDLECTEERAELA 46 +E Q+ + E + + ++ +++ + + RK +V+++ L+ E+ EL Sbjct: 1738 VECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELK 1797 Query: 47 ESRCQ-----------ETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 95 E Q + D+++ + Q + EE+ +K D + ++ LKE Sbjct: 1798 EQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER 1857 Query: 96 ETRAEFTERLVAKLEK 111 + + +LE+ Sbjct: 1858 HGELQDHKEQARRLEE 1873
>gi|41688789|sp|Q96J92|WNK4_HUMAN Serine/threonine-protein kinase WNK4 (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4) Length = 1243 Score = 30.4 bits (67), Expect = 1.2 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 29/134 (21%) Query: 218 KQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSK 277 +++R ++ V+ + K + G M AEDTL +E P P P Sbjct: 735 RRIREIIQRVETLL-KRDTGPMEAAEDTLSPQEEPAP----------------LPALPVP 777 Query: 278 LGDAGRKKREASLSPETKR------SSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 L D ++ ++S S E + SSS P P+ PF P P G + Sbjct: 778 LPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTPISPG------PIFPI 831 Query: 332 REPGKSPDAAPFPP 345 P P +PF P Sbjct: 832 TSPPCHPSPSPFSP 845
Score = 28.1 bits (61), Expect = 6.2 Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 13/85 (15%) Query: 260 RVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDA 319 R R G A+ P+ + R R +S+ S S P P P PP PP A Sbjct: 42 RARRFSGKAEPRPR-------SSRLSRRSSVDLGLLSSWSLPASPA----PDPPDPPDSA 90 Query: 320 GRETLRPKMGSEREP--GKSPDAAP 342 G R S +EP G + AP Sbjct: 91 GPGPARSPPPSSKEPPEGTWTEGAP 115
>gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain protein 12 (Ankyrin repeat-containing cofactor-2) (GAC-1 protein) Length = 2062 Score = 30.4 bits (67), Expect = 1.2 Identities = 26/113 (23%), Positives = 57/113 (50%), Gaps = 6/113 (5%) Query: 12 KHIAEEADRKYEEVPRKLVIIEGDLECTEERA-ELAESRCQ-ETDEQIRLMDQNLKCLSD 69 KH+++E + K E R + E + EE+ +L E R TD+ + + + Sbjct: 739 KHVSKERNFKEE---RDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEE 795 Query: 70 AEEKYSQKEDI-YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 121 + + +++I E++ K + + ++ E R++ E+ + K+E+ T + E K+K Sbjct: 796 SIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIK 848
>gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-associated, coiled-coil containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 30.4 bits (67), Expect = 1.2 Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 12/129 (9%) Query: 9 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 68 +E I + + +E+ +KL +E L + E E +C+ + ++ K Sbjct: 429 RENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLE------KTAK 482 Query: 69 DAEEKYSQKEDI------YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC 122 + EE+ + ++ + E E +L K E + +A+ LE + L+ +L+ Sbjct: 483 ELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLED 542 Query: 123 NKEENLCTQ 131 K+ N +Q Sbjct: 543 LKKRNQNSQ 551
>gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin) Length = 8797 Score = 30.4 bits (67), Expect = 1.2 Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 9/94 (9%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 62 L + L+E+K I D + E + KL + + CTE+ ++ +ET+E +++ Sbjct: 5568 LHQTLLEESKEI----DSELEAMTEKLQYLTS-VYCTEKMSQQVAELGRETEELRQMIKI 5622 Query: 63 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 96 L+ L DA + + +E E+K L L++A+ Sbjct: 5623 RLQNLQDAAKDMKK----FEAELKKLQAALEQAQ 5652
Score = 28.5 bits (62), Expect = 4.7 Identities = 28/156 (17%), Positives = 67/156 (42%), Gaps = 22/156 (14%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVII--------------EGDLECTEERAELAESRCQE 52 +++++K ++E R+ +++ + L I + D + E + S+ E Sbjct: 5419 EVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLME 5478 Query: 53 TDEQI-RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA-------EFTER 104 D + + ++QN + +K + +++++ I+ ++L + A E E Sbjct: 5479 LDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLEL 5538 Query: 105 LVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 140 ++ +EK + N L Q +L+QTLL+ Sbjct: 5539 ILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLE 5574
>gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2) Length = 1124 Score = 30.0 bits (66), Expect = 1.6 Identities = 16/61 (26%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 39 TEERAELAESRCQETDEQIRLMDQNLKCLSDA--EEKYSQKEDIYEEEIKILTDKLKEAE 96 T E E +E +E D+++ + + +C EE+ ++E++ EEE++ ++ +EA+ Sbjct: 1029 TREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAK 1088 Query: 97 T 97 T Sbjct: 1089 T 1089
>gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) Length = 862 Score = 30.0 bits (66), Expect = 1.6 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Query: 49 RCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK 108 R E E+ L ++ K DAE+ S + E+EI L DKL EAE + + E +K Sbjct: 160 RLSEGQEEENLENEMKKAQEDAEKLRSVVMPM-EKEIAALKDKLTEAEDKIKELE--ASK 216 Query: 109 LEKTTDDLEYKLKCNKE 125 +++ LE + C + Sbjct: 217 VKELNHYLEAEKSCRTD 233
Score = 28.5 bits (62), Expect = 4.7 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 18/146 (12%) Query: 15 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 74 A+ ++ EE+ + L + D++ E+ A L +SR Q ++E +RL N + K+ Sbjct: 603 AQASEILLEELQQGLSQAKRDVQ--EQMAVLMQSREQVSEELVRLQKDN----DSLQGKH 656 Query: 75 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN----KEE---N 127 S + + E IL D + + + D +E KLK KE+ Sbjct: 657 SLHVSLQQAEDFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKAEILFLKEQIQAE 716 Query: 128 LCTQRMLYQTL-LDL----NEISSVS 148 C + L +TL L++ EI+S+S Sbjct: 717 QCLKENLEETLQLEIENCKEEIASIS 742
>gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) Length = 1382 Score = 30.0 bits (66), Expect = 1.6 Identities = 24/98 (24%), Positives = 46/98 (46%), Gaps = 11/98 (11%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E ++ Q KE + I +++ EE R + + +ER E + + +E++R Sbjct: 791 LEERKRQRKEERRITYYREKEEEEQRR------AEEQMLKEREERERAERAKREEELREY 844 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR 98 + +K L + E K Q+E EE ++ +E E R Sbjct: 845 QERVKKLEEVERKKRQRELEIEER-----ERRREEERR 877
Score = 29.3 bits (64), Expect = 2.8 Identities = 23/113 (20%), Positives = 50/113 (44%), Gaps = 22/113 (19%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 61 ELQ+++ E + + +EA + +E +E ++ + +E EQI+ + Sbjct: 600 ELQKVRKAEEERLRQEAKEREKE------------RILQEHEQIKKKTVRERLEQIKKTE 647 Query: 62 QNLKCLSDAEEK----------YSQKEDIYEEEIKILTDKLKEAETRAEFTER 104 K D + + +++ + E+E K L ++LK E + ++ ER Sbjct: 648 LGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFER 700
>gi|59803073|sp|O95104|SFR15_HUMAN Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4) Length = 1147 Score = 30.0 bits (66), Expect = 1.6 Identities = 33/148 (22%), Positives = 56/148 (37%), Gaps = 9/148 (6%) Query: 199 ASRRLTRNLYKCIKKAMKQK-QLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEAL 257 A ++L+R YK +K++K L +G+K K E G+ + D + EE+ Sbjct: 559 ALQKLSRGNYKVNQKSIKIAWALNKGIKADYKQYWDVELGVTYIPWDKVKPEEL------ 612 Query: 258 FGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPT 317 G + P G + + E + + + S ++P P+ P P P Sbjct: 613 --ESFCEGGMLDSDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIP 670 Query: 318 DAGRETLRPKMGSEREPGKSPDAAPFPP 345 T+ P +PG A PP Sbjct: 671 VPAPITVPPPQVPPHQPGPPVVGALQPP 698
>gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysaccharide specific response protein 5) Length = 528 Score = 30.0 bits (66), Expect = 1.6 Identities = 30/150 (20%), Positives = 66/150 (44%), Gaps = 24/150 (16%) Query: 3 LQEIQLKEAKHIAEEADRKYEEVP-----RKLVI--------IEGDLECTEERAELAESR 49 L EIQ + +H A + E + +KL+ I+ + E + +L +++ Sbjct: 248 LDEIQAQLEQHDIHNAKLRQENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAK 307 Query: 50 CQETDEQIRLMDQN--------LKCLSDAEEKYSQ---KEDIYEEEIKILTDKLKEAETR 98 Q+T + I+ D+ LK +++ KY Q +E ++++ + DK +E +T Sbjct: 308 LQQTTQLIKEADEKHQREREFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTT 367 Query: 99 AEFTERLVAKLEKTTDDLEYKLKCNKEENL 128 + L + + + K+K ++E + Sbjct: 368 MAKSNELFTTFRQEMEKMTKKIKKLEKETI 397
Score = 28.5 bits (62), Expect = 4.7 Identities = 27/137 (19%), Positives = 61/137 (44%), Gaps = 18/137 (13%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 +E LKEA E+ KYE++ ++ V ++ L ++ E ++ +++E Q Sbjct: 326 REFLLKEAT----ESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQE 381 Query: 64 LKCLSDAEEKYSQKEDIYE--------------EEIKILTDKLKEAETRAEFTERLVAKL 109 ++ ++ +K ++ I+ EE + + K + + E E+L L Sbjct: 382 MEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEEKTVRDKEYKALQIKLERLEKLCRAL 441 Query: 110 EKTTDDLEYKLKCNKEE 126 + ++L K++ KE+ Sbjct: 442 QTERNELNEKVEVLKEQ 458
>gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily member 13 (C-type lectin 13) Length = 539 Score = 30.0 bits (66), Expect = 1.6 Identities = 20/98 (20%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD---QNLKCLSDAEEKYSQKED 79 E ++ +++ DL+ + + A R +TD QI++ +N+ L+ + + Sbjct: 325 ERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMK 384 Query: 80 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 EI+ L +K A T+ L + L+K + +++ Sbjct: 385 NASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
>gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 kDa (Cep63 protein) Length = 703 Score = 30.0 bits (66), Expect = 1.6 Identities = 30/151 (19%), Positives = 64/151 (42%), Gaps = 32/151 (21%) Query: 31 IIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS------------------DAEE 72 +++ ++ C E E + C++ +++ + LK + E+ Sbjct: 345 LLQAEVTCLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQ 404 Query: 73 KYSQKEDIYEEEIKILTDKLKEAE--------TRAEFTERLVAKLEKTTDD-LEYK---- 119 YS + + EI LT +L + + + ++ +RL A+++K D +E+K Sbjct: 405 SYSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILD 464 Query: 120 -LKCNKEENLCTQRMLYQTLLDLNEISSVSI 149 L+ K EN M+ + L L+E +S+ Sbjct: 465 QLESLKLENRHLSEMVMKLELGLHEAKEISL 495
>gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain protein (PTPRF interacting protein) Length = 3038 Score = 30.0 bits (66), Expect = 1.6 Identities = 26/82 (31%), Positives = 32/82 (39%), Gaps = 4/82 (4%) Query: 265 PGAAQTA-PQEPSKL---GDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAG 320 PGAA A P PS+ DA +REA P+ K S +G P P DA Sbjct: 2320 PGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSPDAPAKDAR 2379 Query: 321 RETLRPKMGSEREPGKSPDAAP 342 +G R SP +P Sbjct: 2380 ASLGTLPLGKPRAGAASPLNSP 2401
>gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskeletal 4 (Cytokeratin 4) (K4) (CK4) Length = 534 Score = 30.0 bits (66), Expect = 1.6 Identities = 47/216 (21%), Positives = 83/216 (38%), Gaps = 35/216 (16%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN--- 63 +LK + E+ KYEE K E D ++ + A E + ++ ++ Sbjct: 226 ELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINF 285 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKE-------AETRAEFTE------------- 103 LK L DAE Q + + + + D + AE RA++ E Sbjct: 286 LKVLYDAELSQMQTH-VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALY 344 Query: 104 -RLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEI----SSVSIQISNYSFRG 158 V +L+ + D LK K E RM+ + ++ I ++ + +++ RG Sbjct: 345 QTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRG 404 Query: 159 --CCDDQNKGRFD----GPEAQEEACSGERTYQELL 188 D + R + +A+EE R YQEL+ Sbjct: 405 ENALKDAHSKRVELEAALQQAKEELARMLREYQELM 440
>gi|21542263|sp|Q9C0C2|TABP_HUMAN 182 kDa tankyrase 1-binding protein Length = 1729 Score = 30.0 bits (66), Expect = 1.6 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 267 AAQTAPQEPSKLGDAGRKKREASLS--PETKR----SSSQPRGPVRTHFPFPPKPPTDAG 320 A P +PS L G + L+ P ++ + QP G + PF P+P +A Sbjct: 49 AKPALPAKPSLLVPVGPRPPRGPLAELPSARKMNMPAGPQPYGGSKRPLPFAPRPAVEAS 108 Query: 321 ------RETLRPKMGSEREPGKSPDA 340 +ET + + G E P +P A Sbjct: 109 TGGEATQETGKEEAGKEEPPPLTPPA 134
>gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific protein 8 (Growth arrest-specific 11) Length = 478 Score = 29.6 bits (65), Expect = 2.1 Identities = 54/247 (21%), Positives = 103/247 (41%), Gaps = 25/247 (10%) Query: 14 IAEEADRKYEEVPRK-LVIIEGDLECTEERAELAES--RCQETDEQIRLMDQNLKCLSDA 70 +A++ R E V RK + ++ +L+ E +E+ R + T+E R+ + + + + Sbjct: 126 LAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREI 185 Query: 71 EEKYSQKEDIYEEEIKI-LTDKLKEAETRAE-FTERLVAKLEKTTDDLEYKLKCNKEENL 128 E KY +K + +E+ + +L E E R L+ + E+ D++ NL Sbjct: 186 EAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNL 245 Query: 129 CTQRMLYQTLLDL----NEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTY 184 L + + D+ + + ++S + R D K R + E Q++ + ER Sbjct: 246 ALINSLKEQMEDMRKKEDHLEREMAEVSGQNKR-LADPLQKAREEMSEMQKQLANYERDK 304 Query: 185 QELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAED 244 Q LL T+ K +K +K Q V E Q+F ++ + + Sbjct: 305 QILL--------------CTKARLKVREKELKDLQWEHEVLE-QRFTKVQQERDELYRKF 349 Query: 245 TLPIEEV 251 T I+EV Sbjct: 350 TAAIQEV 356
Score = 28.1 bits (61), Expect = 6.2 Identities = 27/109 (24%), Positives = 55/109 (50%), Gaps = 8/109 (7%) Query: 2 ELQEIQLKE-AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ++ + Q++E I EE DR+ EE R +E D T E+ + +E ++R Sbjct: 25 DMSKEQVEEHVSRIREELDREREE--RNYFQLERDKIHTFW--EITRRQLEEKKAELRNK 80 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 109 D+ ++ +AEE++ + +Y++++K L + + T + +V KL Sbjct: 81 DREME---EAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKL 126
>gi|2498882|sp|Q15459|SF3A1_HUMAN Splicing factor 3 subunit 1 (Spliceosome associated protein 114) (SAP 114) (SF3a120) Length = 793 Score = 29.6 bits (65), Expect = 2.1 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 301 PRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTG 348 P GPV+ P PP PT+ PK +E E D+AP P G Sbjct: 2 PAGPVQA-VPPPPPVPTE-------PKQPTEEEASSKEDSAPSKPVVG 41
>gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) Length = 957 Score = 29.6 bits (65), Expect = 2.1 Identities = 28/144 (19%), Positives = 63/144 (43%), Gaps = 16/144 (11%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 ++ + +AE+ ++ + L D E +E + + ++++ + L+ Sbjct: 434 EINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVK---EVLQA 490 Query: 67 LSDAEEKYSQKEDIYEEEIKI---LTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 123 L + Y QK E++ + LTD+L + T T+R +++L++ + N Sbjct: 491 LEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELS---------N 541 Query: 124 KEENLCTQRMLYQTLLDLNEISSV 147 ++ T+ +L L DL EI + Sbjct: 542 HQKKRATE-ILNLLLKDLGEIGGI 564
>gi|728997|sp|Q07092|CA1F_HUMAN Collagen alpha 1(XVI) chain precursor Length = 1603 Score = 29.6 bits (65), Expect = 2.1 Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 7/76 (9%) Query: 271 APQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTH-FPFPPKPPTDAGRETLRPKMG 329 +P P K+G G P+ ++ S RGP P PP PP G L G Sbjct: 1165 SPGFPGKVGSPGPP------GPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDG 1218 Query: 330 SEREPGKSPDAAPFPP 345 + +PG D P P Sbjct: 1219 KDGKPGLRGDPGPAGP 1234
>gi|23813917|sp|Q13356|PPL2_HUMAN Peptidyl-prolyl cis-trans isomerase like 2 (PPIase) (Rotamase) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) Length = 520 Score = 29.6 bits (65), Expect = 2.1 Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 13/78 (16%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSE 331 P E + A +K + ++PETK SSQP+ G +T R +G Sbjct: 437 PYEEADAQIAQERKTQLKVAPETKVKSSQPQA-------------GSQGPQTFRQGVGKY 483 Query: 332 REPGKSPDAAPFPPRTGA 349 P + AA P T A Sbjct: 484 INPAATKRAAEEEPSTSA 501
>gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) Length = 1742 Score = 29.6 bits (65), Expect = 2.1 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 13/115 (11%) Query: 16 EEADRKYEE-VPRKLVIIEGDLECTEERAELAESRCQETDEQIR-LMDQNLKCLSD---- 69 EE ++Y + V KL ++ E + E + + QE E+++ MD K L D Sbjct: 944 EEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQK 1003 Query: 70 -------AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 E+ + K YE++I+ L +++K + + LV T+D L+ Sbjct: 1004 EERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLK 1058
Score = 28.9 bits (63), Expect = 3.6 Identities = 26/130 (20%), Positives = 54/130 (41%), Gaps = 5/130 (3%) Query: 3 LQEIQLKEAKHIAE---EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 LQ ++ KH+ E K E+ ++L + D+E R + + D ++ Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQL-LESYDIEDVRSRLSVEDLEHLNEDGELWF 1139 Query: 60 MDQNLKCLSDAEEKYSQKE-DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 + LK + E + Q + D YE+EI+ L K+ ++L + + + + Sbjct: 1140 AYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRH 1199 Query: 119 KLKCNKEENL 128 ++ EN+ Sbjct: 1200 EVTRLTSENM 1209
>gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes 4-like 1 protein (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) Length = 1288 Score = 29.6 bits (65), Expect = 2.1 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 18/149 (12%) Query: 14 IAEEADRKYEEVPR-----------KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 62 +AE+A + EV R KL + L+ ++ + S + I+ D+ Sbjct: 873 VAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADR 932 Query: 63 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA-------EFTERLVAKLEKTTDD 115 NL+ D+ + ++ E+E+ LT +LK E +A E + +++K + Sbjct: 933 NLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRN 992 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEI 144 L +LK +E Q+ L L +I Sbjct: 993 LLQELKVIQENEHALQKDALSIKLKLEQI 1021
>gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A) (Kinesin heavy chain neuron-specific 1) Length = 1032 Score = 29.6 bits (65), Expect = 2.1 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 41 ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 E A L C+ET ++ N + + QK YEEEI+ L +L + + Sbjct: 385 EEAALGAELCEETP-----VNDNSSIVVRIAPEERQK---YEEEIRRLYKQLDDKDDEIN 436 Query: 101 FTERLVAKLEKTTDDLEYKLKCNKEENLCTQRML 134 +L+ KL++ D E L + +N QR L Sbjct: 437 QQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
>gi|1174915|sp|P46939|UTRO_HUMAN Utrophin (Dystrophin-related protein 1) (DRP1) (DRP) Length = 3433 Score = 29.6 bits (65), Expect = 2.1 Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 175 EEACSGERTYQELLVNQNPIVQPLA--SRRLTRNLYKCIKKAMKQK 218 E+A ++T E+L NQ P + LA ++ L +N++ ++K KQ+ Sbjct: 944 EKALQEKKTLDEILENQKPALHKLAEETKALEKNVHPDVEKLYKQE 989
>gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death protein 7 (ES18) (HES18) Length = 485 Score = 29.6 bits (65), Expect = 2.1 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 10/100 (10%) Query: 8 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 67 L +A ++ E A R+ E V R+ + + E E +R E +++I +KC+ Sbjct: 226 LTQAAYVGE-ARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRW--RVKCV 282 Query: 68 SDAEEKYSQKEDIYEEEIKILTD-KLKEAETRAEFTERLV 106 + EEK E+E+K D L E + T+R+V Sbjct: 283 QEVEEKKR------EQELKAAADGVLSEVRKKQADTKRMV 316
>gi|33302611|sp|P12036|NFH_HUMAN Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H) Length = 1026 Score = 29.6 bits (65), Expect = 2.1 Identities = 67/336 (19%), Positives = 121/336 (36%), Gaps = 58/336 (17%) Query: 40 EERAELAESRCQETDEQIRLMDQNLKCLSDA-----EEKYSQKEDI--YEEEIKILTDKL 92 E RA+L Q T + L LS+A + S +E+I Y +++ T +L Sbjct: 273 EIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTEL 332 Query: 93 KEAETRAEFTERLVAKLE-----------KTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 + ++ + ER ++LE + L+ +L+ K E + Q YQ LL++ Sbjct: 333 EALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWE-MAAQLREYQDLLNV 391 Query: 142 NEISSVSIQISNYSFRG--CCDDQNKGRFDGPE---------------AQEEACSGERTY 184 + I G C F PE ++E+ E++ Sbjct: 392 KMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSE 451 Query: 185 QELLVNQNPIVQPLASRRLTRNLYKCIKKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAED 244 +E ++ + + + +T ++ K+ + G +E + E G E+ Sbjct: 452 KETVIVEEQTEETQVTEEVT-------EEEEKEAKEEEGKEEEGGEEEEAEGG----EEE 500 Query: 245 TL--PIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPR 302 T P EE PE A +E +A ++E + SP +S + + Sbjct: 501 TKSPPAEEAASPEK---------EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551 Query: 303 GPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSP 338 P + PP+ + E P E KSP Sbjct: 552 SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
>gi|60416429|sp|O43516|WASIP_HUMAN Wiskott-Aldrich syndrome protein interacting protein (WASP interacting protein) (PRPL-2 protein) Length = 503 Score = 29.6 bits (65), Expect = 2.1 Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 4/71 (5%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSS----SQPRGPVRTHFPFPPKPPTDAGRETLRPK 327 P P +G+ REA P + + S PR + P PP PP+ G L P Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324 Query: 328 MGSEREPGKSP 338 E + P Sbjct: 325 SSGNDETPRLP 335
Score = 28.9 bits (63), Expect = 3.6 Identities = 17/58 (29%), Positives = 23/58 (39%), Gaps = 4/58 (6%) Query: 292 PETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGK----SPDAAPFPP 345 P ++R R P P PP PP T R + + P + SP + P PP Sbjct: 360 PPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP 417
Score = 28.9 bits (63), Expect = 3.6 Identities = 28/108 (25%), Positives = 35/108 (32%), Gaps = 26/108 (24%) Query: 264 RPGAAQTAPQEPSKLGDA--GRKKREASLSPETKRSSSQPRGPV--RTHFPFPPKPPTDA 319 +P T P P G A G R++ LS + S+ P P R PP PP Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271 Query: 320 GRE----------------------TLRPKMGSEREPGKSPDAAPFPP 345 G T RP S+ P P + P PP Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP 319
>gi|20138588|sp|Q14766|LTBL_HUMAN Latent transforming growth factor beta binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1 binding protein 1) (TGF-beta1-BP-1) Length = 1595 Score = 29.6 bits (65), Expect = 2.1 Identities = 22/64 (34%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 281 AGRKKREASLSP-ETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPD 339 AG R + P E R +S+P G PP PP + R + P PG P Sbjct: 70 AGAPSRASPGVPSERTRRTSKPGGAALQGLRPPPPPPPEPARPAV-PGGQLHPNPGGHPA 128 Query: 340 AAPF 343 AAPF Sbjct: 129 AAPF 132
>gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI Length = 1285 Score = 29.3 bits (64), Expect = 2.8 Identities = 26/112 (23%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Query: 15 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 74 A + ++ EE +L I+ ++E +R E E R ++ +E+ R+ + EE+ Sbjct: 912 ALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEER 971 Query: 75 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 ++ED +E +I + + + E + A LE+ D E L+ + E Sbjct: 972 KKRED---DEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE 1020
>gi|38605641|sp|Q9Y3Q4|HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 Length = 1203 Score = 29.3 bits (64), Expect = 2.8 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 19/102 (18%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQP---------------RGPVRTHF 309 P AAQ +P P G G + P ++ SS P GP+ T Sbjct: 936 PQAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPE 995 Query: 310 --PFPPKPPT-DAGRETLRPKMGSEREPGKSPDA-APFPPRT 347 P P+PP+ AG +G G SP +P PPRT Sbjct: 996 TPPRQPEPPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRT 1037
>gi|1709337|sp|P55209|NPL1_HUMAN Nucleosome assembly protein 1-like 1 (NAP-1 related protein) (hNRP) Length = 391 Score = 29.3 bits (64), Expect = 2.8 Identities = 45/199 (22%), Positives = 76/199 (38%), Gaps = 43/199 (21%) Query: 3 LQEIQLK----EAKHIAE--EADRKYEEV-----PRKLVIIEGDLECTEERAELAESRCQ 51 L+ +Q+K EAK E + +RKY + ++ II E TEE E Sbjct: 81 LKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEED 140 Query: 52 ETDEQIRLMDQNLKCLSDAEEKYSQKED---------IYEEEIKILTDKLKEA-ETRAEF 101 E E+++ K + E+K +KED + + +L+D ++E E + Sbjct: 141 EISEELKE-----KAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKH 195 Query: 102 TERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCD 161 + + K + + L+ + E N E + + Y R D Sbjct: 196 LKDIKVKFSDAGQPMSFVLEFHFEPN---------------EYFTNEVLTKTYRMRSEPD 240 Query: 162 DQNKGRFDGPEAQEEACSG 180 D + FDGPE C+G Sbjct: 241 DSDPFSFDGPEIM--GCTG 257
>gi|9296963|sp|Q9Y463|DYR1B_HUMAN Dual-specificity tyrosine-phosphorylation regulated kinase 1B (Mirk protein kinase) (Minibrain-related kinase) Length = 629 Score = 29.3 bits (64), Expect = 2.8 Identities = 22/75 (29%), Positives = 24/75 (32%), Gaps = 3/75 (4%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETL 324 PG P +P LG R S P S GP P P P L Sbjct: 536 PGTGAQLPPQPRYLG---RPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASAL 592 Query: 325 RPKMGSEREPGKSPD 339 R +M R P PD Sbjct: 593 RTRMTGGRPPLPPPD 607
>gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin) Length = 756 Score = 29.3 bits (64), Expect = 2.8 Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 18/110 (16%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAE-----SRCQETDEQ 56 +L+E +L+ + + EE R+ E L C ER + E +R Q+ DE+ Sbjct: 507 QLKEQELRACEMVLEETRRQKE------------LLCKMEREKSIEIENLQTRLQQLDEE 554 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKL-KEAETRAEFTERL 105 + CL E+ +++ +EI+ LT +L +E E + +RL Sbjct: 555 NSELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRL 604
>gi|133498|sp|P13631|RRG1_HUMAN Retinoic acid receptor gamma-1 (RAR-gamma-1) Length = 454 Score = 29.3 bits (64), Expect = 2.8 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 254 PEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPP 313 P A G +R P +P LG K ASLS ET+ +SS+ P P PP Sbjct: 26 PFAFPGALRGSPPFEMLSPSFRG-LGQPDLPKEMASLSVETQSTSSEEMVP---SSPSPP 81 Query: 314 KPP 316 PP Sbjct: 82 PPP 84
>gi|131005|sp|P10163|PR4S_HUMAN Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A] Length = 247 Score = 29.3 bits (64), Expect = 2.8 Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 10/76 (13%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPP-----KPPTDAGRETLRP 326 P +P + G + + + P K P+G ++H P PP +PP G ++ Sbjct: 96 PGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQS--- 152 Query: 327 KMGSEREPGKSPDAAP 342 G PGK P+ P Sbjct: 153 -QGPPPHPGK-PEGPP 166
Score = 28.9 bits (63), Expect = 3.6 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 268 AQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPK 327 +Q P P K G +E + S + +P+GP + P PP + P Sbjct: 152 SQGPPPHPGK--PEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPA 209 Query: 328 MGSERE----PGKSPDAAPFPPRTG 348 G+ ++ P P P PP+ G Sbjct: 210 GGNPQQPQDPPAGKPQGPPPPPQGG 234
>gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 3 Length = 914 Score = 29.3 bits (64), Expect = 2.8 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 18/107 (16%) Query: 47 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKIL------TDKLKEAETRAE 100 +++ Q T E L D+N++CL E +EEIK L T L +++ Sbjct: 317 DAQRQLTMELHELQDRNMECLGMLHES--------QEEIKELRSRSGPTAHLYFSQSYGA 368 Query: 101 FT-ERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISS 146 FT E L A++E T + KL ++E +L Q+ + + D I++ Sbjct: 369 FTGESLAAEIEGT---MRKKLSLDEESSLFKQKAQQKRVFDTVRIAN 412
>gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel) Length = 5038 Score = 29.3 bits (64), Expect = 2.8 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 16/114 (14%) Query: 23 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 82 E+V + L +IE ++ EE E E +E DE+ + D+ EE +KED + Sbjct: 1857 EDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDE--------EETAQEKEDEEK 1908 Query: 83 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 136 EE ++ E E E L+ K + ++ ++ C+ E C Q + ++ Sbjct: 1909 EE-----EEAAEGEKEEGLEEGLLQM--KLPESVKLQM-CHLLEYFCDQELQHR 1954
>gi|41688792|sp|Q9BYP7|WNK3_HUMAN Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) Length = 1743 Score = 29.3 bits (64), Expect = 2.8 Identities = 22/98 (22%), Positives = 41/98 (41%), Gaps = 1/98 (1%) Query: 239 MVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSS 298 +V + T+ VLGP + + + P Q PQ G +++ A L P+ RS Sbjct: 644 LVQGQSTVLPVHVLGPTVV-SQPQVSPLTVQKVPQIKPVSQPVGAEQQAALLKPDLVRSL 702 Query: 299 SQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGK 336 +Q + + P P + ++ ++ + S P K Sbjct: 703 NQDVATTKENVSSPDNPSGNGKQDRIKQRRASCPRPEK 740
>gi|41688816|sp|Q96T58|MINT_HUMAN Msx2-interacting protein (SPEN homolog) (SMART/HDAC1 associated repressor protein) Length = 3664 Score = 29.3 bits (64), Expect = 2.8 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 11/67 (16%) Query: 254 PEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPP 313 P A G V+ P A APQ+P K EA+ +P+ K + + PV P P Sbjct: 3210 PRAADGVVKVPP--ASKAPQQPGK---------EAAKTPDAKAAPTPTPAPVPVPVPLPA 3258 Query: 314 KPPTDAG 320 P G Sbjct: 3259 PAPAPHG 3265
>gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L) Length = 544 Score = 29.3 bits (64), Expect = 2.8 Identities = 25/115 (21%), Positives = 55/115 (47%), Gaps = 13/115 (11%) Query: 28 KLVIIEGDLEC--TEERAELAE---------SRCQETDEQIRLMDQNLKCLSDAEEKYSQ 76 ++ I DL+ T+E+A+L + R E ++Q ++++ L L + S+ Sbjct: 74 QVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSR 133 Query: 77 KEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQ 131 +YE+EI+ L ++A T + + L + E+ ++ L+ EE + ++ Sbjct: 134 FRALYEQEIRDLRLAAEDATTNEK--QALRGEREEGLEETLRNLQARYEEEVLSR 186
>gi|45476939|sp|Q8IX07|FOG1_HUMAN Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1) Length = 1004 Score = 29.3 bits (64), Expect = 2.8 Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 12/60 (20%) Query: 301 PRGPVRTH------------FPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTG 348 P PVRT P PP P E+ RP GS PG +P +P P G Sbjct: 732 PAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADG 791
>gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-containing protein 1A) (SH3P17) Length = 1721 Score = 29.3 bits (64), Expect = 2.8 Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Query: 7 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 66 QL+ A+ +E +R+ +E R+L + E LE E E ++ E+ + L+ Sbjct: 385 QLERAEQERKERERQEQERKRQLEL-EKQLEKQRELERQREEERRKEIERREAAKRELER 443 Query: 67 LSDAEEKYSQKEDIY------EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 E + ++++++ +E+I +L K K E E +LE D+ +L Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503 Query: 121 KCNKEE 126 ++E Sbjct: 504 TTQRQE 509
>gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein) Length = 731 Score = 28.9 bits (63), Expect = 3.6 Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 5/112 (4%) Query: 2 ELQEI--QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 59 +LQ++ Q+ K +E + + E + ++ IE DL T+ + SR ++ DE+I+ Sbjct: 513 QLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQ---SRIKDRDEEIQK 569 Query: 60 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 111 + L + + S+ E+ + + L K E+ + LV +LE+ Sbjct: 570 LRNQLTNKTLSNSSQSELENRLHQLTETLIQKQTMLESLSTEKNSLVFQLER 621
>gi|1708973|sp|P51608|MECP2_HUMAN Methyl-CpG-binding protein 2 (MeCP-2 protein) (MeCP2) Length = 486 Score = 28.9 bits (63), Expect = 3.6 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 14/119 (11%) Query: 212 KKAMKQKQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTA 271 KKA+K+ +R V+E + K + V E ++EV+ P L + + G Sbjct: 285 KKAVKESSIR-SVQETVLPIKKRKTRETVSIE----VKEVVKP-LLVSTLGEKSGKGLKT 338 Query: 272 PQEPS-KLGDAGRKKREASLSPETKRS-------SSQPRGPVRTHFPFPPKPPTDAGRE 322 + P K ++ K R +S S K+ S P+ PV P PP PP E Sbjct: 339 CKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSE 397
>gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like protein B3) (RB3) Length = 189 Score = 28.9 bits (63), Expect = 3.6 Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 19 DRKYEEVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQ 76 D EE+ +KL E + E LAE R E + + +++N + A+EK +Q Sbjct: 88 DPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQ 147 Query: 77 K----EDIYEEEIKILTDKLKEAETRAE 100 K ++ E + + ++L+E + AE Sbjct: 148 KMESNKENREAHLAAMLERLQEKDKHAE 175
>gi|21362754|sp|Q12796|PNR1_HUMAN Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (B4-2 protein) Length = 327 Score = 28.9 bits (63), Expect = 3.6 Identities = 23/83 (27%), Positives = 31/83 (37%), Gaps = 4/83 (4%) Query: 264 RPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRG--PVRTHFPFPPKPPTDAGR 321 +P A P L AG R A K+ + P G P R H +P + GR Sbjct: 71 QPRAPAALPNR--SLAVAGGTPRAAPKKRRKKKVRASPAGQLPSRFHQYQQHRPSLEGGR 128 Query: 322 ETLRPKMGSEREPGKSPDAAPFP 344 G++ PG + AP P Sbjct: 129 SPATGPSGAQEVPGPAAALAPSP 151
>gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1 (Neuron- and testis-specific protein 1) (37 kDa neuronal protein) Length = 353 Score = 28.9 bits (63), Expect = 3.6 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 30 VIIEGDLECTEERAELAESRCQETDEQIRLMDQN------LKCLSDAEEKYSQKEDIYEE 83 V+ E + E+R L ES + IR++ N +CL E+ + E + Sbjct: 187 VLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDA 246 Query: 84 EIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 +IK L E + + RL L+K + Sbjct: 247 QIKFLNTYQNPGEKLSAYVIRLEPLLQKVVE 277
>gi|139820|sp|P18887|XRCC1_HUMAN DNA-repair protein XRCC1 Length = 633 Score = 28.9 bits (63), Expect = 3.6 Identities = 30/132 (22%), Positives = 50/132 (37%), Gaps = 25/132 (18%) Query: 224 VKEVQKFVNKGEKGIMVLAE--DTLPI--EEVLGPEALFGRVRWRPGAAQTAPQE----- 274 VKE + N G + + T P+ + GP ++ A+ +P Sbjct: 175 VKEEDESANSLRPGALFFSRINKTSPVTASDPAGPSYAAATLQASSAASSASPVSRAIGS 234 Query: 275 PSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREP 334 SK ++ + KR+ L+ E K++ S+P + P PK P P Sbjct: 235 TSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPA----------------P 278 Query: 335 GKSPDAAPFPPR 346 ++P AP P R Sbjct: 279 TRTPATAPVPAR 290
>gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (Liver membrane-bound protein) (HSPC001) (UNQ169/PRO195) Length = 323 Score = 28.9 bits (63), Expect = 3.6 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 48 SRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVA 107 S CQ D+ I L L+C S E YSQ ++ Y + ++L AE R E L+ Sbjct: 78 SICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLG-CQNQLPFAELRQEQLMSLMP 136 Query: 108 KL 109 K+ Sbjct: 137 KM 138
>gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE family member 6) Length = 732 Score = 28.9 bits (63), Expect = 3.6 Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Query: 72 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQ 131 EK ++ E+EI L LKE +++ + L+A + K+ LE + K K + + Sbjct: 88 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ-IAEA 146 Query: 132 RMLYQTLLDLNEISSVSIQ 150 +++ +T E +++I+ Sbjct: 147 KIICKTFKMSEERRAIAIK 165
>gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 (Lymphocyte-oriented kinase) Length = 968 Score = 28.9 bits (63), Expect = 3.6 Identities = 33/171 (19%), Positives = 66/171 (38%), Gaps = 26/171 (15%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELAESRCQETDEQIRLMDQN 63 E++ + E +K EE +K +++ D + E ELA R TD + + D+ Sbjct: 667 EVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLT-TDNRREICDKE 725 Query: 64 LKCLSDAEE------------------------KYSQKEDIYEEEIKILTDKLKEAETRA 99 +CL +E K K+ + + ++L KE E Sbjct: 726 RECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQ 785 Query: 100 EFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQ 150 + +R++ +L+ + +L + T+ +Y+ L +N S + Q Sbjct: 786 RYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHINGGGSAAEQ 836
>gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kDa protein (U5-102 kDa protein) Length = 941 Score = 28.9 bits (63), Expect = 3.6 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 +E + ++ A+ + EEA R YE+ P KL +++G +E +E E A + ++ Sbjct: 684 LEWVQDNIRAAQDLCEEALRHYEDFP-KLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHS 742 Query: 61 DQNLKCLSDAEEKYSQ 76 LS EEK Q Sbjct: 743 TPLWLLLSRLEEKIGQ 758
>gi|131011|sp|P10162|PR4L_HUMAN Basic salivary proline-rich protein 4 allele L (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Peptide P-D] Length = 276 Score = 28.9 bits (63), Expect = 3.6 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 268 AQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPK 327 +Q P P K G +E + S + +P+GP + P PP + P Sbjct: 181 SQGPPPHPGK--PEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPP 238 Query: 328 MGSERE----PGKSPDAAPFPPRTG 348 G+ ++ P P P PP+ G Sbjct: 239 GGNPQQPQAPPAGKPQGPPPPPQGG 263
Score = 28.1 bits (61), Expect = 6.2 Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 275 PSKLGDAGRKKREASLSPE--TKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSER 332 P + G+ R R P+ ++ ++P+GP P P PP ++ P G + Sbjct: 195 PPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPPGGNPQQPQAPPAGKPQ 254 Query: 333 EPGKSPDAAPFPPR 346 P P PPR Sbjct: 255 GPPPPPQGGR-PPR 267
>gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 45 (RING finger protein 99) Length = 580 Score = 28.9 bits (63), Expect = 3.6 Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 24/120 (20%) Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 124 K L E+ +QKE+ + + L L + T EFTE L+ + DLE Sbjct: 294 KLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLT----SGSDLEI------ 343 Query: 125 EENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCCDDQNKGRFDGPEAQEEACSGERTY 184 L T+R++ + L LN++ YS R +D K RF P+ + C G Y Sbjct: 344 ---LITKRVVVERLRKLNKV--------QYSTRPGVND--KIRF-CPQEKAGQCRGYEIY 389
>gi|20141192|sp|O60885|BRD4_HUMAN Bromodomain-containing protein 4 (HUNK1 protein) Length = 1362 Score = 28.9 bits (63), Expect = 3.6 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 289 SLSPETKRSSSQPRGPVRTHFPFPPK-PPTDAGRETLRPKMGSEREPGKSPD 339 SL PE + + PV H P P+ P D GR +RP + PG +PD Sbjct: 1128 SLRPEPPKHPESIKAPV--HLPQRPEMKPVDVGRPVIRPPEQNAPPPG-APD 1176
>gi|13123997|sp|Q9Y6D6|BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor) Length = 1849 Score = 28.9 bits (63), Expect = 3.6 Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 14/109 (12%) Query: 207 LYKCIKKAMKQKQLRRGVKEVQKFVN-KGEKGIMVLAEDT----LPIEEVLGPEALFGRV 261 LY C+++ +Q R G ++ V GEK + + + T L I + P AL + Sbjct: 1485 LYWCVQQDNEQLA-RSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHAL---L 1540 Query: 262 RWRPGAAQTAPQEPSKLGD-----AGRKKREASLSPETKRSSSQPRGPV 305 WRP + +TAP PS + + +K + S + + ++P+ P+ Sbjct: 1541 TWRPNSGETAPPPPSPVSEKPLDTISQKSVDIHDSIQPRSVDNRPQAPL 1589
>gi|18202099|sp|O60902|SHOX2_HUMAN Short stature homeobox protein 2 (Paired-related homeobox protein SHOT) (Homeobox protein Og12X) Length = 331 Score = 28.9 bits (63), Expect = 3.6 Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 16/111 (14%) Query: 72 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQ 131 E +KED E + T K+K+ +R FT + +LE+ D+ Y +EE +Q Sbjct: 119 ELKDRKEDAKGMEDEGQT-KIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREE--LSQ 175 Query: 132 RMLYQTLLDLNEISSVSIQISNYSFRGCCDDQ----NKGRFDGPEAQEEAC 178 R+ +S +Q+ + R C Q +KG G +Q EAC Sbjct: 176 RL---------GLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEAC 217
>gi|13432104|sp|P13942|CA2B_HUMAN Collagen alpha 2(XI) chain precursor Length = 1736 Score = 28.9 bits (63), Expect = 3.6 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 12/113 (10%) Query: 234 GEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPE 293 GEKG L+ + P E GP G+ R GA K G G + P Sbjct: 823 GEKGARGLSGKSGPRGE-RGPTGPRGQ-RGPRGAT-------GKSGAKGTSGGDGPHGPP 873 Query: 294 TKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPG-KSPDAAPFPP 345 +R P+GP FP P PP G++ L G E G + P PP Sbjct: 874 GERGLPGPQGP--NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 924
Score = 28.5 bits (62), Expect = 4.7 Identities = 23/84 (27%), Positives = 34/84 (40%), Gaps = 10/84 (11%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREAS------LSPETKRSSSQPRGPVRTHFPFPPKPPTD 318 P P P + G+ G + + + P+ + P G R H P PP PP + Sbjct: 896 PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE-RGH-PGPPGPPGE 953 Query: 319 AGRETLRPKMGSEREPGKSPDAAP 342 G K G++ +PG P AP Sbjct: 954 QGLPGTAGKEGTKGDPG--PPGAP 975
>gi|52001471|sp|P10161|PR4M_HUMAN Basic salivary proline-rich protein 4 allele M (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Peptide P-D] Length = 238 Score = 28.9 bits (63), Expect = 3.6 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 268 AQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPK 327 +Q P P K G +E + S + +P+GP + P PP + P Sbjct: 143 SQGPPPHPGK--PEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPP 200 Query: 328 MGSERE----PGKSPDAAPFPPRTG 348 G+ ++ P P P PP+ G Sbjct: 201 GGNPQQPQAPPAGKPQGPPPPPQGG 225
Score = 28.1 bits (61), Expect = 6.2 Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 275 PSKLGDAGRKKREASLSPE--TKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSER 332 P + G+ R R P+ ++ ++P+GP P P PP ++ P G + Sbjct: 157 PPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPPGGNPQQPQAPPAGKPQ 216 Query: 333 EPGKSPDAAPFPPR 346 P P PPR Sbjct: 217 GPPPPPQGGR-PPR 229
>gi|51315800|sp|Q9UPA5|BSN_HUMAN Bassoon protein (Zinc-finger protein 231) Length = 3926 Score = 28.9 bits (63), Expect = 3.6 Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 8/76 (10%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFP-----FPPKPPTDAGRETLRP 326 P + G G + S ET R++S P GP + P P+PP T P Sbjct: 261 PDQERSRGPGG--PQPGSRQAETARATSVP-GPAQAAAPPEVGRVSPQPPQPTKPSTAEP 317 Query: 327 KMGSEREPGKSPDAAP 342 + + P KS A P Sbjct: 318 RPPAGEAPAKSATAVP 333
Score = 28.1 bits (61), Expect = 6.2 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 16/91 (17%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHF-----PFPPKPPTDAGRETLRP 326 PQ PS L AGR RE LS + ++F P P P+++ T P Sbjct: 1436 PQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSES--PTFSP 1493 Query: 327 -KMG-------SEREPGKSPDAAPFPPRTGA 349 KMG S + P +P A+ P GA Sbjct: 1494 GKMGPRATAEFSTQTPSPAP-ASDMPRSPGA 1523
>gi|29337113|sp|Q96AJ9|VT1A_HUMAN Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2) Length = 203 Score = 28.5 bits (62), Expect = 4.7 Identities = 35/166 (21%), Positives = 70/166 (42%), Gaps = 29/166 (17%) Query: 5 EIQLKEAKHIAEEADRKYEEVP-----------RKLVIIEGDLECTEERAELAESRCQET 53 E QL+EAK + E+ D + E+P R G LE +R+ +A S Sbjct: 42 EKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYS----- 96 Query: 54 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 113 +++R N D +Q+ + + T++L+ + R E ++ + E+ Sbjct: 97 -DEVR----NELLGDDGNSSENQRAHLLDN-----TERLERSSRRLEAGYQIAVETEQIG 146 Query: 114 DDLEYKLKCNKEENLCTQRMLYQTLLDLNEISSVSIQISNYSFRGC 159 ++ L ++E+ + L +T +L + S + ++ RGC Sbjct: 147 QEMLENLSHDREKIQRARERLRETDANLGKSSRI---LTGMLRRGC 189
>gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3) Length = 256 Score = 28.5 bits (62), Expect = 4.7 Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 59 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL-- 116 L D N EE + + IY+ + L+E + AE ER K+++ D + Sbjct: 173 LYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILRE-DAPAEHVERFFEKMDRNQDGVVT 231 Query: 117 --EYKLKCNKEENLCTQRMLYQTLL 139 E+ C K+EN+ + L++ ++ Sbjct: 232 IEEFLEACQKDENIMSSMQLFENVI 256
>gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X) Length = 483 Score = 28.5 bits (62), Expect = 4.7 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 16/108 (14%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E++ ++ K +E+ R Y E R + E +ER R + +E+ R + Sbjct: 328 ELKDEKPKRPEDESGRDYRERER-------EYERDQERILRERERLKRQEEERRRQKERY 380 Query: 65 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 112 + E+ + +KE EE+K D L++ +AE TE + EKT Sbjct: 381 ----EKEKTFKRKE----EEMKKEKDTLRDKGKKAESTES-IGSSEKT 419
>gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1) Length = 775 Score = 28.5 bits (62), Expect = 4.7 Identities = 28/127 (22%), Positives = 58/127 (45%), Gaps = 5/127 (3%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 ++L+ L A D EE + +++ +E + ++A + Q T + +L Sbjct: 401 LDLENKTLALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLC 460 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD-DLEYK 119 D + S+A + Y++E+K +LKE R + ++V K + T D +L + Sbjct: 461 DLEIMPSSEAADGEKATALYYQQELK----QLKEEFERYKMRAQVVLKSKNTKDGNLGKE 516 Query: 120 LKCNKEE 126 L+ +E+ Sbjct: 517 LEAAQEQ 523
>gi|3122058|sp|Q13201|MRN1_HUMAN Multimerin 1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4) Length = 1228 Score = 28.5 bits (62), Expect = 4.7 Identities = 41/201 (20%), Positives = 78/201 (38%), Gaps = 16/201 (7%) Query: 4 QEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 63 Q IQ ++ A +K+ V + +E + + ++ I+ ++ Sbjct: 425 QIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVK 484 Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV----AKLEKTTDDLEYK 119 L A E+ + +Y E + KLKE + TE++ A ++ + + Sbjct: 485 QTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTE 544 Query: 120 LKCNKEENLCTQR-MLYQTLLDLNEISS------VSIQISNYSFRGCCDD-----QNKGR 167 EN+ Q M+ Q DL+ S VS+++ S RG C+D +N + Sbjct: 545 YMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFK 604 Query: 168 FDGPEAQEEACSGERTYQELL 188 F + +E +T E+L Sbjct: 605 FQLKDTEENLHVLNQTLAEVL 625
>gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain) Length = 3110 Score = 28.5 bits (62), Expect = 4.7 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 6/108 (5%) Query: 14 IAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI-RLMDQNLKCLSDAEE 72 + +E D+ +E+ RK +E E E+ AE+ ++ + +N + D E Sbjct: 1717 LQKEIDQMIKELRRKN--LETQKEIAEDELVAAEALLKKVKKLFGESRGENEEMEKDLRE 1774 Query: 73 K---YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 117 K Y K D + ++ TDK++EA ++ + LEK + +E Sbjct: 1775 KLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVE 1822
>gi|547700|sp|Q01101|INSM1_HUMAN Zinc finger protein IA-1 (Insulinoma-associated protein 1) Length = 510 Score = 28.5 bits (62), Expect = 4.7 Identities = 17/61 (27%), Positives = 24/61 (39%), Gaps = 3/61 (4%) Query: 286 REASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMG---SEREPGKSPDAAP 342 R LSP + ++P P P PP PP + L + + P + P AA Sbjct: 28 RALLLSPSCGGARAEPPAPSPVPGPLPPPPPAERAHAALAAALACAPGPQPPPQGPRAAH 87 Query: 343 F 343 F Sbjct: 88 F 88
>gi|60390213|sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) Length = 655 Score = 28.5 bits (62), Expect = 4.7 Identities = 25/108 (23%), Positives = 41/108 (37%), Gaps = 14/108 (12%) Query: 243 EDTLPIEEVL-GPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQP 301 +D P+ + L P A R+ RP + PQ + ++ R+ S S E R + Sbjct: 317 QDHRPLAQPLPNPSAPLRRIYERPSTTCSKPQRVKQNSESERR----SPSSEDDRDERES 372 Query: 302 RGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRTGA 349 R ++ + E +PK R P + + P PP A Sbjct: 373 RAEIQNAEDY---------NEIFQPKNSISRTPPRRSEPFPAPPEDDA 411
>gi|52000732|sp|Q99700|ATX2_HUMAN Ataxin-2 (Spinocerebellar ataxia type 2 protein) Length = 1312 Score = 28.5 bits (62), Expect = 4.7 Identities = 20/73 (27%), Positives = 31/73 (42%), Gaps = 4/73 (5%) Query: 249 EEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETK----RSSSQPRGP 304 E GPE V+ A + + + DA + R+++L+P K RS SQP+ Sbjct: 872 EHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPS 931 Query: 305 VRTHFPFPPKPPT 317 P P P+ Sbjct: 932 TTPTSPRPQAQPS 944
>gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2) Length = 1272 Score = 28.5 bits (62), Expect = 4.7 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 13/104 (12%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE-------QIRLMDQNLKCLS 68 EE+ R+ +++ R+ +I G + + + + E E DE + N ++ Sbjct: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053 Query: 69 DAEEKY------SQKEDIYEEEIKILTDKLKEAETRAEFTERLV 106 + EE+ + E+ EE LTD KE ET E TE ++ Sbjct: 1054 EPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMI 1097
>gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal D protein homolog 2 Length = 824 Score = 28.5 bits (62), Expect = 4.7 Identities = 32/134 (23%), Positives = 60/134 (44%), Gaps = 17/134 (12%) Query: 71 EEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 130 E ++++++ YE E + LT+K+ E + L+A+LEK +LK + T Sbjct: 464 EAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEK-------ELKKVSDVAGET 516 Query: 131 QRMLYQTLLDLNEISSVSIQISNYSFRGC-CDDQNKGRF------DGPEAQEEACSGERT 183 Q L + +E+ + S +++N C C+++ R +G G RT Sbjct: 517 QGSL---SVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGGAGRTSPGGRT 573 Query: 184 YQELLVNQNPIVQP 197 E ++PI+ P Sbjct: 574 SPEARGRRSPILLP 587
>gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like protein c20orf80 Length = 182 Score = 28.5 bits (62), Expect = 4.7 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 25/110 (22%) Query: 36 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 95 + C E A+S+ +E I++ S AE++ +K+DI EE+ +K+ Sbjct: 89 IRCNEAGDIEAKSKTAGEEEMIKIR-------SCAEKETKKKDDIPEED----KGNVKQC 137 Query: 96 ETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR-----MLYQTLLD 140 E + ++K ++KLK +KEE+ ++ L++TLLD Sbjct: 138 E---------INYVKKFQSFQDHKLKISKEESKILKKAQKDGFLHETLLD 178
>gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 (Ubiquitin thiolesterase 35) (Ubiquitin-specific processing protease 35) (Deubiquitinating enzyme 35) Length = 1017 Score = 28.5 bits (62), Expect = 4.7 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 34 GDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK 93 G EER E E +E E+ + ++ + E + ++E++ EEE K+ + K Sbjct: 667 GGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGERE--KEEEVEEEEEKVEKETEK 724 Query: 94 EAETRAE 100 EAE E Sbjct: 725 EAEQEKE 731
>gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin subfamily A member 1 (Golgin-97) Length = 767 Score = 28.5 bits (62), Expect = 4.7 Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 31/152 (20%) Query: 22 YEEVPRKLVIIEGDLECTEERAELAESR-CQETDE-----QIRLMDQNLKCLSDAEEKYS 75 Y E R L I+ LE E+ + + R QE +E + ++ + L+ ++++S Sbjct: 77 YAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWS 136 Query: 76 QKEDIYEEEIKILTDKLKEA--------ETRAEFTE-------------RLVAKLEKTTD 114 +K D E+E ILT +L+E + R E E ++ K E++ Sbjct: 137 EKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLG 196 Query: 115 DLEYKLKCNKEENLCTQRMLYQTLLDLNEISS 146 +E +L+ E TQ + L++ N++SS Sbjct: 197 KMEQELEARTRELSRTQ----EELMNSNQMSS 224
>gi|29336893|sp|Q96DN6|MBD6_HUMAN Methyl-CpG-binding domain protein 6 (Methyl-CpG binding protein MBD6) Length = 1003 Score = 28.5 bits (62), Expect = 4.7 Identities = 22/83 (26%), Positives = 30/83 (36%), Gaps = 2/83 (2%) Query: 265 PGAAQTAPQEPSKL--GDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRE 322 PGA + Q P L G G + +P +S P + PP+ P Sbjct: 755 PGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLP 814 Query: 323 TLRPKMGSEREPGKSPDAAPFPP 345 P E EP + P +A PP Sbjct: 815 PESPASALEPEPARPPLSALAPP 837
>gi|20177873|sp|Q9UQB3|CTD2_HUMAN Catenin delta-2 (Delta-catenin) (Neural plakophilin-related ARM-repeat protein) (NPRAP) (Neurojungin) (GT24) Length = 1225 Score = 28.5 bits (62), Expect = 4.7 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 20/89 (22%) Query: 275 PSKLGDAGRKKREA--SLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSER 332 PS+L G + R S S T + GP P PP PP RE P +GS Sbjct: 185 PSQLPARGTQARATGQSFSQGTTSRAGHLAGPE----PAPPPPPPP--REPFAPSLGSAF 238 Query: 333 EPGKSPDAA------------PFPPRTGA 349 +P AA P PPR G+ Sbjct: 239 HLPDAPPAAAAAALYYSSSTLPAPPRGGS 267
>gi|30580335|sp|O75167|PHR2_HUMAN Phosphatase and actin regulator 2 Length = 634 Score = 28.5 bits (62), Expect = 4.7 Identities = 29/128 (22%), Positives = 48/128 (37%), Gaps = 9/128 (7%) Query: 231 VNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASL 290 V K E+G ++E T P+EE + AA P + K +++ + Sbjct: 115 VVKSEEGNGSVSEKTPPLEEQAEDKKENTENHSETPAAPALPPSAPPKPRSKPKPKKSPV 174 Query: 291 SPETKRSSSQPRG----PVRTHFPFPPK-----PPTDAGRETLRPKMGSEREPGKSPDAA 341 P+ + + +G P++ + P K PP A R T R GS + A Sbjct: 175 PPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTGSKA 234 Query: 342 PFPPRTGA 349 P T + Sbjct: 235 SASPSTSS 242
>gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein) Length = 693 Score = 28.5 bits (62), Expect = 4.7 Identities = 34/135 (25%), Positives = 51/135 (37%), Gaps = 21/135 (15%) Query: 12 KHIAEEADRKYEEV---------------PRKLVIIEGDLECTEERAELAESRCQETDEQ 56 + + +EA +EV L+ E E+ L E Q EQ Sbjct: 298 EQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ 357 Query: 57 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 116 RL +QN + + Q E + ++E +L++ E R E + K EK D Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQE-----QRLRKQEERLRKEEERLQKQEKRLWDQ 412 Query: 117 EYKLKCNKEENLCTQ 131 E +L KEE L Q Sbjct: 413 EERL-WKKEERLQKQ 426
>gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal D protein homolog 1 Length = 975 Score = 28.5 bits (62), Expect = 4.7 Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 10/128 (7%) Query: 8 LKEAKHIAEEADRKY-----EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM-- 60 L+ +K + E D + EE V I G LE E + +A + + +I+ + Sbjct: 381 LQSSKELKAELDGEKGRDSGEEAHDYEVDING-LEILECKYRVAVTEVIDLKAEIKALKE 439 Query: 61 --DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 118 +++++ +D + KY K +Y+E++ L KE+ + E+ + K+ ++ Sbjct: 440 KYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHS 499 Query: 119 KLKCNKEE 126 L ++E Sbjct: 500 TLNTAQDE 507
>gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9) Length = 4486 Score = 28.5 bits (62), Expect = 4.7 Identities = 21/100 (21%), Positives = 46/100 (46%), Gaps = 13/100 (13%) Query: 2 ELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES----------RCQ 51 +L +++ ++H+ EEA+ + V + + + G L +E + + C Sbjct: 577 DLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPCM 636 Query: 52 ETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 91 E+ E R M Q + + EKY + +YE+ + +++K Sbjct: 637 ESAEGKR-MQQKYEDMLSLLEKYETR--LYEDWCRTVSEK 673
>gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinase interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3) Length = 1334 Score = 28.5 bits (62), Expect = 4.7 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 8/87 (9%) Query: 51 QETDEQIRLMDQNLKCLS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 109 +E +EQ+ + K L AEEK+ + ED E+E K L +++ E + T +L K Sbjct: 87 REDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKKELQIQVEHYEFQ---TRQLELKA 143 Query: 110 EKTTDDL----EYKLKCNKEENLCTQR 132 + D + E + + KE N QR Sbjct: 144 KNYADQISRLEERESEMKKEYNALHQR 170
>gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11) (MEA6/MEA11) Length = 804 Score = 28.5 bits (62), Expect = 4.7 Identities = 16/55 (29%), Positives = 28/55 (50%) Query: 72 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 EK ++ E+EI L +LKE +++ + L+A + K LE + K K + Sbjct: 132 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 186
>gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) Length = 681 Score = 28.1 bits (61), Expect = 6.2 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 12/91 (13%) Query: 58 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL--EKTTDD 115 R+ DQ D K KED YE + ++ D K + AE E+ KL +KT ++ Sbjct: 432 RIRDQ---AWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEE 488 Query: 116 LEYKLKCNKEENLCTQRMLYQTLLDLNEISS 146 E++ Q+M+ L L+ +S+ Sbjct: 489 -------ENPEHVEIQKMMDSLFLKLDALSN 512
>gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein) Length = 482 Score = 28.1 bits (61), Expect = 6.2 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 14/70 (20%) Query: 64 LKCLSDAEEKYSQKEDIYEEEIKILT-----------DKLKEAETRAEFTERLVAKLEKT 112 L+CL AEE Q+ EE ++T D+L+EA+ ++T ++ +K Sbjct: 71 LECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQ---KYTGKIGNVCKKL 127 Query: 113 TDDLEYKLKC 122 + YKL+C Sbjct: 128 SSPSNYKLEC 137
>gi|1345650|sp|Q02388|CO7A1_HUMAN Collagen alpha 1(VII) chain precursor (Long-chain collagen) (LC collagen) Length = 2944 Score = 28.1 bits (61), Expect = 6.2 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 8/71 (11%) Query: 275 PSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREP 334 P LG+AG K P R G R P PP GR+ G + EP Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAG--RPGAKGPEGPPGPTGRQ------GEKGEP 1536 Query: 335 GKSPDAAPFPP 345 G+ D A P Sbjct: 1537 GRPGDPAVVGP 1547
>gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal 9 (Cytokeratin 9) (K9) (CK 9) Length = 622 Score = 28.1 bits (61), Expect = 6.2 Identities = 28/148 (18%), Positives = 67/148 (45%), Gaps = 13/148 (8%) Query: 17 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN--LKCLSDAEEKY 74 + + +YE + +L+ ++ + + EE ++L + + +I + K L+D ++Y Sbjct: 272 DLEMQYETLQEELMALKKNHK--EEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEY 329 Query: 75 SQ-----KEDI---YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 Q ++DI YE +I + ++ + + + + V +L +LE +L+ + Sbjct: 330 EQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSK 389 Query: 127 NLCTQRMLYQTL-LDLNEISSVSIQISN 153 ++ L T ++ + QISN Sbjct: 390 KAALEKSLEDTKNRYCGQLQMIQEQISN 417
>gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreductase PDSW subunit (Complex I-PDSW) (CI-PDSW) Length = 172 Score = 28.1 bits (61), Expect = 6.2 Identities = 12/55 (21%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR--AEFTERLVAKLEKTT 113 ++++ C+ +AE ++ + + +E I I+ D+LK + R + + + ++E+ T Sbjct: 73 EEDIMCMYEAEMQWKRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFT 127
Score = 28.1 bits (61), Expect = 6.2 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Query: 6 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI-RLMDQNL 64 I+ + AK+ R+Y VP E D+ C E AE+ R + D++I +M L Sbjct: 46 IERQHAKNRYYYYHRQYRRVPDITECKEEDIMCMYE-AEMQWKRDYKVDQEIINIMQDRL 104 Query: 65 KCLSDAEEKYSQKEDIYEEE 84 K E + Q+ I E E Sbjct: 105 KACQQREGQNYQQNCIKEVE 124
>gi|27805394|sp|O60641|AP180_HUMAN Clathrin coat assembly protein AP180 (Clathrin coat associated protein AP180) (91 kDa synaptosomal-associated protein) Length = 907 Score = 28.1 bits (61), Expect = 6.2 Identities = 24/100 (24%), Positives = 34/100 (34%), Gaps = 8/100 (8%) Query: 253 GPEALFGRVRWRPGAAQT--APQEPSKLGDAGRKKREASLSPETKRSSSQPRG------P 304 G + L G W+P A + P G +S+ P S G P Sbjct: 785 GEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVPPTSSVPPVAGAPSVGQPGAGFGMPP 844 Query: 305 VRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFP 344 T P P+ P + +RP G+ PG +P P Sbjct: 845 AGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSPSPTP 884
>gi|1711641|sp|P17600|SYN1_HUMAN Synapsin-1 (Synapsin I) (Brain protein 4.1) Length = 705 Score = 28.1 bits (61), Expect = 6.2 Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 14/93 (15%) Query: 268 AQTAPQEPSKLGDAGRKKREASLSPET----KRSSSQPRGPVRTHFPFPPKPPTDAGRET 323 AQ P++ + GR + SP +++S QP GP P P P G Sbjct: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGP 474 Query: 324 LR---------PKMGSEREPGKSPDA-APFPPR 346 R P G + G P A +P P R Sbjct: 475 QRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQR 507
>gi|34098740|sp|Q9NYF0|DAC1_HUMAN Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene-3 protein) Length = 836 Score = 28.1 bits (61), Expect = 6.2 Identities = 23/94 (24%), Positives = 41/94 (43%) Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 126 L +A ++ +E EE I +L +L R + +L+K DL ++ EE Sbjct: 90 LGEAAQRSRLEEKFLEENILLLRKQLNCLRRRDAGLLNQLQELDKQISDLRLDVEKTSEE 149 Query: 127 NLCTQRMLYQTLLDLNEISSVSIQISNYSFRGCC 160 +L T +L++ +S S+ S+ S C Sbjct: 150 HLETDSRPSSGFYELSDGASGSLSNSSNSVFSEC 183
>gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein C20orf23 (Sorting nexin 23) Length = 1317 Score = 28.1 bits (61), Expect = 6.2 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 10/131 (7%) Query: 5 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 64 E Q +E E + EE+ K + +LE ++ E + QIR +++L Sbjct: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658 Query: 65 KCLSD----------AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 114 K S AE++ ++E + E++ L K +E ET E L E + Sbjct: 659 KRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNN 718 Query: 115 DLEYKLKCNKE 125 + K + +E Sbjct: 719 EKAEKFQIFQE 729
>gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein) Length = 2033 Score = 28.1 bits (61), Expect = 6.2 Identities = 18/69 (26%), Positives = 32/69 (46%) Query: 82 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 141 EEE + L +++ AET R ++L++ D + + ++E +R Q L L Sbjct: 1554 EEEARRLRERIDRAETLGRTWSREESELQRARDQADQECGRLQQELRALERQKQQQTLQL 1613 Query: 142 NEISSVSIQ 150 E S + Q Sbjct: 1614 QEESKLLSQ 1622
>gi|6016211|sp|P78426|NK61_HUMAN Homeobox protein Nkx-6.1 Length = 367 Score = 28.1 bits (61), Expect = 6.2 Identities = 14/34 (41%), Positives = 17/34 (50%) Query: 291 SPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETL 324 S + SSS P P+ TH P KPP G +L Sbjct: 50 SSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSL 83
>gi|8928568|sp|Q12888|TP53B_HUMAN Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (53BP1) Length = 1972 Score = 28.1 bits (61), Expect = 6.2 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 1/74 (1%) Query: 259 GRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRS-SSQPRGPVRTHFPFPPKPPT 317 G++ R G +QT + GDAG R+ +P T R + R P RT P Sbjct: 1359 GKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPG 1418 Query: 318 DAGRETLRPKMGSE 331 G E + P + + Sbjct: 1419 PLGIEDISPNLSPD 1432
>gi|57012964|sp|Q92922|SMRC1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) Length = 1105 Score = 28.1 bits (61), Expect = 6.2 Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 8/64 (12%) Query: 284 KKREASLSPETKRSSSQPRGPVRTHFPFPPKP-PTDA-------GRETLRPKMGSEREPG 335 K E SPE + + R H P PP P PT++ G+ +L K S++E Sbjct: 303 KNEEPVRSPERRDRKASANARKRKHSPSPPPPTPTESRKKSGKKGQASLYGKRRSQKEED 362 Query: 336 KSPD 339 + D Sbjct: 363 EQED 366
>gi|29429203|sp|P54259|DRPLA_HUMAN Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein) Length = 1185 Score = 28.1 bits (61), Expect = 6.2 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 289 SLSPETKRSSSQPRGPVRTHFPFP-----PKPPTDAGRETLRPKMGSEREPGKSPDA--A 341 S+ ++ SS +GP R + P P P+PP R+ P+ E P +P A Sbjct: 140 SVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ---PEASFEPHPSVTPTGYHA 196 Query: 342 PFPPRT 347 P P T Sbjct: 197 PMEPPT 202
>gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia 1 protein Length = 854 Score = 28.1 bits (61), Expect = 6.2 Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 82 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 120 +E IK L LKE T+ +E+ + L K +D+E +L Sbjct: 547 QERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQL 585
>gi|38258268|sp|Q9UPQ9|K1093_HUMAN Protein KIAA1093 Length = 1723 Score = 28.1 bits (61), Expect = 6.2 Identities = 13/22 (59%), Positives = 14/22 (63%) Query: 404 PSLGQLTPAHPKGKTPSVPQNG 425 PSL Q T A P G +PS P NG Sbjct: 45 PSLSQPTAASPIGSSPSPPVNG 66
>gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (Ubiquitin thiolesterase 5) (Ubiquitin-specific processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T) Length = 858 Score = 27.7 bits (60), Expect = 8.1 Identities = 17/64 (26%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 45 LAESRCQETD---EQIR-LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 + E C+ ++ E R L+++ +KCL+ + KY+Q+ D Y ++ + D E E Sbjct: 446 MVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD-YIMQLPVPMDAALNKEELLE 504 Query: 101 FTER 104 + E+ Sbjct: 505 YEEK 508
>gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 protein) Length = 339 Score = 27.7 bits (60), Expect = 8.1 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 6/100 (6%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 60 M+L++++ KE K +EA RK + L E + E EE E A + E+I Sbjct: 99 MKLEKLREKERK---KEAKRKISSLSFTL---EEEEEGGEEEEEAAMYEEEMEREEITTK 152 Query: 61 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 100 + L D + + D EEE ++ + +E E + E Sbjct: 153 KRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
>gi|135846|sp|P20962|PTMS_HUMAN Parathymosin Length = 102 Score = 27.7 bits (60), Expect = 8.1 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 9/93 (9%) Query: 11 AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA 70 AK + E+ ++ E+ RK E E EE AE +ET E D+ + Sbjct: 14 AKDLKEKKEKVEEKASRK----ERKKEVVEEEENGAEEEEEETAEDGEEEDE-----GEE 64 Query: 71 EEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 103 E++ ++ED +K ++ EA+ + + TE Sbjct: 65 EDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
>gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Villin 2) Length = 586 Score = 27.7 bits (60), Expect = 8.1 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 36 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 95 LE ++R E E +E ++ +R ++ + L D EEK + E E+I+ +E Sbjct: 323 LETEKKRRETVE---REKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRALQLEEER 379 Query: 96 ETRAEFTERLVA 107 + E ERL A Sbjct: 380 KRAQEEAERLEA 391
>gi|12229810|sp|Q9NYJ7|DLL3_HUMAN Delta-like protein 3 precursor (Drosophila Delta homolog 3) Length = 618 Score = 27.7 bits (60), Expect = 8.1 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 17/62 (27%) Query: 254 PEALFGRVRWRPGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPP 313 P LF RV +PG ++ A + P LG A+LS RGPV T P P Sbjct: 55 PCRLFFRVCLKPGLSEEAAESPCALG--------AALSA---------RGPVYTEQPGAP 97 Query: 314 KP 315 P Sbjct: 98 AP 99
>gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 378 Score = 27.7 bits (60), Expect = 8.1 Identities = 43/183 (23%), Positives = 72/183 (39%), Gaps = 42/183 (22%) Query: 1 MELQEIQLKEAKHIAEEADRKYEEVPRKLVIIE----GDLECTEERAELAESRCQETDEQ 56 ME + + +E E RK E RKL +E G E +AE + R +E + Sbjct: 40 MEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWE 99 Query: 57 IRL---------MDQNLKCLS------------------DAEEKYSQKE----DIYEEEI 85 +L M N+ LS D+EE QK + YE++I Sbjct: 100 QKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQI 159 Query: 86 KILTDKLKEAETRAEFTERLVAKLEKTTD-------DLEYKLKCNKEENLCTQRMLYQTL 138 K + +++ ++ + E+T + DLE + KC E + Q ++ Q + Sbjct: 160 KHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFI 219 Query: 139 LDL 141 L+L Sbjct: 220 LEL 222
>gi|461675|sp|P29400|CA54_HUMAN Collagen alpha 5(IV) chain precursor Length = 1685 Score = 27.7 bits (60), Expect = 8.1 Identities = 22/72 (30%), Positives = 25/72 (34%), Gaps = 1/72 (1%) Query: 275 PSKLGDAGRKKREASLSPETKRSSSQPRGPV-RTHFPFPPKPPTDAGRETLRPKMGSERE 333 P G G + +L P+ R P GP RT P P D G MG Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815 Query: 334 PGKSPDAAPFPP 345 PG P PP Sbjct: 816 PGIGVQGPPGPP 827
>gi|38372706|sp|Q8NGJ4|O52E2_HUMAN Olfactory receptor 52E2 Length = 325 Score = 27.7 bits (60), Expect = 8.1 Identities = 10/27 (37%), Positives = 18/27 (66%) Query: 193 PIVQPLASRRLTRNLYKCIKKAMKQKQ 219 P++ P+ T+ +YKC+KK + Q+Q Sbjct: 286 PMLNPVIYGVRTKQIYKCVKKILLQEQ 312
>gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21) Length = 488 Score = 27.7 bits (60), Expect = 8.1 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Query: 12 KHIAEEADRKYEEVPRKLVIIEGDLECTEE--RAELAESRCQETDEQIRLM---DQNLKC 66 + + +E K + V ++L E + E E R E + Q E+ R+ DQ Sbjct: 134 EEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSI 193 Query: 67 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 109 L++ E++ Q+ EEE K DK EAE ++LV +L Sbjct: 194 LNNEEQRELQR---LEEEEKKTLDKFAEAEDELVQQKQLVREL 233
>gi|34098675|sp|Q96D71|REP1_HUMAN RalBP1 associated Eps domain containing protein 1 (RalBP1-interacting protein 1) Length = 744 Score = 27.7 bits (60), Expect = 8.1 Identities = 15/57 (26%), Positives = 24/57 (42%), Gaps = 2/57 (3%) Query: 289 SLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREP--GKSPDAAPF 343 ++ P T + +P PV + PP P + + P G+ P G P +PF Sbjct: 96 TVQPRTSADAQEPASPVVSPQQSPPTSPHTWRKHSRHPSGGNSERPLAGPGPFWSPF 152
>gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated protein 1 (HAP-1) (Neuroan 1) Length = 671 Score = 27.7 bits (60), Expect = 8.1 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 17/81 (20%) Query: 56 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 115 Q+ L D+ L+ SD++E+ +E+ EE KEAE E E+ +D Sbjct: 245 QVNLRDELLQLYSDSDEEDEDEEEEEEE---------KEAEEEQE--------EEEAEED 287 Query: 116 LEYKLKCNKEENLCTQRMLYQ 136 L+ C+ + + + +L+Q Sbjct: 288 LQCAHPCDAPKLISQEALLHQ 308
>gi|6136124|sp|O75385|ULK1_HUMAN Serine/threonine-protein kinase ULK1 (Unc-51-like kinase 1) Length = 1050 Score = 27.7 bits (60), Expect = 8.1 Identities = 28/91 (30%), Positives = 34/91 (37%), Gaps = 12/91 (13%) Query: 254 PEALFGRVRWRPGAAQT-APQEPSKLGDAGRKKREASLSPETK--------RSSSQPR-G 303 P G + RPG + T +PQ G GR R S +PE R S P Sbjct: 504 PSPQVGTIPERPGWSGTPSPQGAEMRG--GRSPRPGSSAPEHSPRTSGLGCRLHSAPNLS 561 Query: 304 PVRTHFPFPPKPPTDAGRETLRPKMGSEREP 334 + P PKPPTD P S +P Sbjct: 562 DLHVVRPKLPKPPTDPLGAVFSPPQASPPQP 592
>gi|29429200|sp|P53814|SMOO_HUMAN Smoothelin Length = 917 Score = 27.7 bits (60), Expect = 8.1 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 5/51 (9%) Query: 297 SSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPPRT 347 +SS P P + P P+PP E + + PG SP+ P PP+T Sbjct: 198 TSSSPASPSSSPTPASPEPPL----EPAEAQCLTAEVPG-SPEPPPSPPKT 243
>gi|17433253|sp|Q9NZQ3|SP90_HUMAN SH3 adapter protein SPIN90 (NCK interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein interacting protein) (Dia interacting protein-1) (DIP-1) Length = 722 Score = 27.7 bits (60), Expect = 8.1 Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 5/58 (8%) Query: 288 ASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETLRPKMGSEREPGKSPDAAPFPP 345 +S S +T +SS P P + P PP P T+ S+ +P S +AP PP Sbjct: 219 SSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTV-----SQVQPPPSKASAPEPP 271
>gi|6686051|sp|O00294|TULP1_HUMAN Tubby related protein 1 (Tubby-like protein 1) Length = 542 Score = 27.7 bits (60), Expect = 8.1 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 11/73 (15%) Query: 280 DAGRKKREASLSPETKRSSSQPRGPV------RTHFPFPPKPPTDAGRETLRPKMGSERE 333 D+G + E SLSPE R Q P RT P P P G + +P G Sbjct: 15 DSGHE--EESLSPEAPRRPKQRPAPAQRLRKKRTEAPESPCP---TGSKPRKPGAGRRGR 69 Query: 334 PGKSPDAAPFPPR 346 P + P P R Sbjct: 70 PREEPSPDPAQAR 82
>gi|28380068|sp|Q14686|NCOA6_HUMAN Nuclear receptor coactivator 6 (Amplified in breast cancer-3 protein) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator-2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein) Length = 2063 Score = 27.7 bits (60), Expect = 8.1 Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 1/49 (2%) Query: 272 PQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAG 320 PQ P+ + + E SLSPE +S P + + P PP+P + G Sbjct: 1222 PQTPNNRPPS-TEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRG 1269
>gi|21263906|sp|Q99954|PRL5_HUMAN Proline-rich protein 5 precursor (Proline-rich protein PBI) Length = 134 Score = 27.7 bits (60), Expect = 8.1 Identities = 24/80 (30%), Positives = 30/80 (37%), Gaps = 15/80 (18%) Query: 265 PGAAQTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRETL 324 PG +Q P+ P G L+P PR P T F PP PP G Sbjct: 19 PGESQRGPRGPYPPGP---------LAPPPP-----PRFPFGTGFVPPPHPPP-YGPGRF 63 Query: 325 RPKMGSEREPGKSPDAAPFP 344 P + PG+ P + P P Sbjct: 64 PPPLSPPYGPGRIPPSPPPP 83
>gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein) Length = 915 Score = 27.7 bits (60), Expect = 8.1 Identities = 30/137 (21%), Positives = 57/137 (41%), Gaps = 3/137 (2%) Query: 16 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 75 ++AD E + ++EG+++ E+ + +ET + + L + EE Sbjct: 151 DDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFTILQEIEEPSL 210 Query: 76 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLY 135 + E+ E+ + IL + K + E +E L + T + K +EE+L Sbjct: 211 EPEN--EKILDILGETCKSEPVKEESSE-LEQPFAQDTSSVGPDRKLAEEEDLFDSAHPE 267 Query: 136 QTLLDLNEISSVSIQIS 152 + LDL S+ Q S Sbjct: 268 EGDLDLASESTAHAQSS 284
>gi|46397803|sp|O60732|MGC1_HUMAN Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7) Length = 1142 Score = 27.7 bits (60), Expect = 8.1 Identities = 22/82 (26%), Positives = 32/82 (39%), Gaps = 4/82 (4%) Query: 269 QTAPQEPSKLGDAGRKKREASLSPETKRSSSQPRGPVRTHFPFPPKPPTDAGRET--LRP 326 Q++ Q P + + PE+ S S P GPV++ P PP ++ P Sbjct: 622 QSSLQSPVSICSSSTPSSLPQSFPES--SQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSP 679 Query: 327 KMGSEREPGKSPDAAPFPPRTG 348 + E E SP P P G Sbjct: 680 ESAPEGEDSLSPLQIPQSPLEG 701
>gi|1730095|sp|P52954|LBX1_HUMAN Transcription factor LBX1 Length = 280 Score = 27.7 bits (60), Expect = 8.1 Identities = 21/81 (25%), Positives = 33/81 (40%) Query: 218 KQLRRGVKEVQKFVNKGEKGIMVLAEDTLPIEEVLGPEALFGRVRWRPGAAQTAPQEPSK 277 ++++ V+ +K G+ I+ LAE E G GR + RPG+ P P Sbjct: 184 EEMKADVESPKKLGPSGQMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPKA 243 Query: 278 LGDAGRKKREASLSPETKRSS 298 G + AS + SS Sbjct: 244 PGRCALQLSPASPLTDQPASS 264
>gi|20141212|sp|P20849|CA19_HUMAN Collagen alpha 1(IX) chain precursor Length = 921 Score = 27.7 bits (60), Expect = 8.1 Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 14/85 (16%) Query: 265 PGA-AQTAPQ-EPSKLGDAGRKKREASLSPETKRSSSQP-RGPVRTHFPFPPKPPTDAGR 321 PGA T P P +G G+K P S P RG P PP PP AG Sbjct: 322 PGADGLTGPDGSPGSIGSKGQKGE-----PGVPGSRGFPGRG-----IPGPPGPPGTAGL 371 Query: 322 ETLRPKMGSEREPG-KSPDAAPFPP 345 ++G +PG + P P PP Sbjct: 372 PGELGRVGPVGDPGRRGPPGPPGPP 396
>gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) Length = 1816 Score = 27.7 bits (60), Expect = 8.1 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 17/96 (17%) Query: 15 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 74 AE R +E R+ +E E R AE R ++ +E+ R ++ K DAEEK Sbjct: 1582 AERRARLQDEERRRQQQLE------EMRKREAEDRARQEEERRRQEEERTK--RDAEEKR 1633 Query: 75 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE 110 Q+E Y EAE R + E LE Sbjct: 1634 RQEEGYYSR---------LEAERRRQHDEAARRLLE 1660
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.313 0.132 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 1,077,553 Number of Sequences: 164271 Number of extensions: 56380 Number of successful extensions: 425 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 322 Number of HSP's gapped (non-prelim): 136 length of query: 437 length of database: 6,424,444 effective HSP length: 98 effective length of query: 339 effective length of database: 5,257,754 effective search space: 1782378606 effective search space used: 1782378606 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 60 (27.7 bits)
