BLASTP 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. RID: 1111158951-8383-90581717080.BLASTQ2 Query= GENSCAN (3): 207 aa (206 letters) Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters If you have any problems or questions with the results of this search please refer to the BLAST FAQs Taxonomy reports
RID: 1111158951-8383-90581717080.BLASTQ2
Query= GENSCAN (3): 207 aa (206 letters)
Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters
If you have any problems or questions with the results of this search please refer to the BLAST FAQs
Taxonomy reports
Score E Sequences producing significant alignments: (bits) Value gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain ... 200 2e-52 gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (T... 190 3e-49 gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (A... 177 2e-45 gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Trop... 173 4e-44 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 46 8e-06 gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Di... 44 4e-05 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 44 5e-05 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 42 1e-04 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 42 2e-04 gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (... 42 2e-04 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 41 2e-04 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 41 2e-04 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 40 4e-04 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 40 5e-04 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 40 5e-04 gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 40 5e-04 gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium ... 40 5e-04 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 40 7e-04 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 40 7e-04 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 40 7e-04 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 39 0.001 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 39 0.001 gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-acti... 39 0.002 gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein ... 38 0.002 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 38 0.002 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 38 0.003 gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat pr... 38 0.003 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 38 0.003 gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen... 38 0.003 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 37 0.004 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 37 0.005 gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin... 37 0.005 gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylat... 37 0.005 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 37 0.005 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 37 0.006 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 37 0.006 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 37 0.006 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 36 0.010 gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of... 36 0.010 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 35 0.013 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 35 0.013 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 35 0.013 gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor... 35 0.017 gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond s... 35 0.017 gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 35 0.017 gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kin... 35 0.017 gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated pr... 35 0.017 gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation ini... 35 0.017 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 35 0.017 gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein ki... 35 0.023 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 35 0.023 gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 35 0.023 gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein... 35 0.023 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 35 0.023 gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Pl... 35 0.023 gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor rec... 34 0.030 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 34 0.039 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 34 0.039 gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X 34 0.039 gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modula... 33 0.051 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 33 0.051 gi|464541|sp|P35241|RADI_HUMAN Radixin 33 0.066 gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornif... 33 0.066 gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly ... 33 0.086 gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein... 33 0.086 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 33 0.086 gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain prot... 33 0.086 gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleo... 32 0.11 gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DN... 32 0.11 gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B 32 0.11 gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 32 0.11 gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like pr... 32 0.15 gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (His... 32 0.15 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 32 0.15 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 32 0.15 gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine rec... 32 0.15 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 32 0.15 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 32 0.15 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 32 0.19 gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myos... 32 0.19 gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin conden... 32 0.19 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 32 0.19 gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 31 0.25 gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein 31 0.25 gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,... 31 0.25 gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat p... 31 0.25 gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (C... 31 0.25 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 31 0.33 gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific pro... 31 0.33 gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precur... 31 0.33 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 31 0.33 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 31 0.33 gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi... 31 0.33 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 31 0.33 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 31 0.33 gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleo... 30 0.43 gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1... 30 0.43 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 30 0.43 gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate... 30 0.43 gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor 30 0.43 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 30 0.43 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 30 0.43 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 30 0.43 gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein ki... 30 0.43 gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL... 30 0.56 gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effecto... 30 0.56 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 30 0.56 gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily... 30 0.56 gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal... 30 0.56 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 30 0.73 gi|55976224|sp|O94972|TM37_HUMAN Tripartite motif protein 3... 30 0.73 gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding prot... 30 0.73 gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chai... 30 0.73 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 30 0.73 gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysac... 30 0.73 gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death prot... 30 0.73 gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain... 30 0.73 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 30 0.73 gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI 29 0.95 gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense tra... 29 0.95 gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting p... 29 0.95 gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skel... 29 0.95 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 29 0.95 gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-... 29 0.95 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 29 1.2 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 29 1.2 gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1... 29 1.2 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 29 1.2 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 29 1.2 gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (... 29 1.2 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 29 1.2 gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist... 28 1.6 gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 prot... 28 1.6 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 28 1.6 gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE fam... 28 1.6 gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclero... 28 1.6 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 28 1.6 gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense tra... 28 1.6 gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like pro... 28 1.6 gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-termin... 28 1.6 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 28 1.6 gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinas... 28 1.6 gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-... 28 1.6 gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein ... 28 2.1 gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Vi... 28 2.1 gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kD... 28 2.1 gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreduct... 28 2.1 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 28 2.1 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 28 2.1 gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia... 28 2.1 gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal... 28 2.8 gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting pro... 28 2.8 gi|135846|sp|P20962|PTMS_HUMAN Parathymosin 28 2.8 gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 3... 28 2.8 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 28 2.8 gi|13431957|sp|O60763|VDP_HUMAN General vesicular transport... 28 2.8 gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated prot... 28 2.8 gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin ... 28 2.8 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 28 2.8 gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) 28 2.8 gi|119360|sp|P14625|ENPL_HUMAN Endoplasmin precursor (94 kD... 27 3.6 gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal... 27 3.6 gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa parane... 27 3.6 gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M prote... 27 3.6 gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain pr... 27 3.6 gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled... 27 3.6 gi|13638422|sp|Q01538|MYT1_HUMAN Myelin transcription facto... 27 4.7 gi|18202499|sp|Q14331|FRG1_HUMAN FRG1 protein (FSHD region ... 27 4.7 gi|21759000|sp|Q12955|ANK3_HUMAN Ankyrin 3 (ANK-3) (Ankyrin G) 27 4.7 gi|38372394|sp|Q9NUV9|GIM4_HUMAN GTPase, IMAP family member... 27 4.7 gi|21431832|sp|O75683|SUR6_HUMAN Surfeit locus protein 6 27 4.7 gi|9297020|sp|Q13402|MYO7A_HUMAN Myosin VIIa 27 4.7 gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 4... 27 4.7 gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 ... 27 4.7 gi|45477011|sp|O75113|N4B1_HUMAN Nedd4-binding protein 1 (N... 27 4.7 gi|20137932|sp|Q9BXL6|CARE_HUMAN Caspase recruitment domain... 27 4.7 gi|20138768|sp|Q9NZM3|ITN2_HUMAN Intersectin 2 (SH3 domain-... 27 4.7 gi|547754|sp|P35908|K22E_HUMAN Keratin, type II cytoskeleta... 27 4.7 gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-... 27 4.7 gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskele... 27 4.7 gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentri... 27 4.7 gi|1706622|sp|P52732|KIF11_HUMAN Kinesin-like protein KIF11... 27 6.2 gi|48428133|sp|Q96M83|CCD7_HUMAN Coiled-coil domain contain... 27 6.2 gi|6707663|sp|P78363|ABCA4_HUMAN Retinal-specific ATP-bindi... 27 6.2 gi|20532406|sp|P17980|PRS6A_HUMAN 26S protease regulatory s... 27 6.2 gi|57015409|sp|Q8IWT3|PARC_HUMAN p53-associated parkin-like... 27 6.2 gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p1... 27 6.2 gi|30580600|sp|O00463|TRA5_HUMAN TNF receptor associated fa... 27 6.2 gi|20138891|sp|O75925|PIAS1_HUMAN Protein inhibitor of acti... 27 6.2 gi|12229723|sp|Q9ULD4|BRF3_HUMAN Bromodomain and PHD finger... 27 6.2 gi|47606762|sp|Q96MU7|YT521_HUMAN Putative splicing factor ... 26 8.1 gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonuc... 26 8.1 gi|6831676|sp|O15266|SHOX_HUMAN Short stature homeobox prot... 26 8.1 gi|2500771|sp|Q16181|SEPT7_HUMAN Septin 7 (CDC10 protein ho... 26 8.1 gi|22653670|sp|Q9UIG0|BAZ1B_HUMAN Bromodomain adjacent to z... 26 8.1 gi|47116932|sp|Q9NQ29|L7L1_HUMAN Putative RNA-binding prote... 26 8.1 gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein ty... 26 8.1 gi|125351|sp|P16591|FER_HUMAN Proto-oncogene tyrosine-prote... 26 8.1 gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (... 26 8.1 gi|13626094|sp|Q9UGM1|ACH9_HUMAN Neuronal acetylcholine rec... 26 8.1 gi|6166119|sp|O60879|DIAP2_HUMAN Diaphanous protein homolog... 26 8.1 gi|41017271|sp|O60237|MPT2_HUMAN Protein phosphatase 1 regu... 26 8.1 gi|20978544|sp|O00232|PSDC_HUMAN 26S proteasome non-ATPase ... 26 8.1 gi|41017595|sp|O95153|RIP1_HUMAN Peripheral-type benzodiaze... 26 8.1 gi|18202489|sp|Q12852|M3K12_HUMAN Mitogen-activated protein... 26 8.1 gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment facto... 26 8.1 gi|45645200|sp|Q92599|SEP8_HUMAN Septin 8 26 8.1 gi|14548075|sp|O14645|IDLC_HUMAN Axonemal dynein light inte... 26 8.1 gi|55976571|sp|Q96L91|EP400_HUMAN E1A binding protein p400 ... 26 8.1 gi|22653668|sp|Q9UIF8|BAZ2B_HUMAN Bromodomain adjacent to z... 26 8.1 Alignments
Score E Sequences producing significant alignments: (bits) Value gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain ... 200 2e-52 gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (T... 190 3e-49 gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (A... 177 2e-45 gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Trop... 173 4e-44 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 46 8e-06 gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Di... 44 4e-05 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 44 5e-05 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 42 1e-04 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 42 2e-04 gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (... 42 2e-04 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 41 2e-04 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 41 2e-04 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 40 4e-04 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 40 5e-04 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 40 5e-04 gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 40 5e-04 gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium ... 40 5e-04 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 40 7e-04 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 40 7e-04 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 40 7e-04 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 39 0.001 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 39 0.001 gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-acti... 39 0.002 gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein ... 38 0.002 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 38 0.002 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 38 0.003 gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat pr... 38 0.003 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 38 0.003 gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen... 38 0.003 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 37 0.004 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 37 0.005 gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin... 37 0.005 gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylat... 37 0.005 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 37 0.005 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 37 0.006 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 37 0.006 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 37 0.006 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 36 0.010 gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of... 36 0.010 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 35 0.013 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 35 0.013 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 35 0.013 gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor... 35 0.017 gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond s... 35 0.017 gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 35 0.017 gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kin... 35 0.017 gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated pr... 35 0.017 gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation ini... 35 0.017 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 35 0.017 gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein ki... 35 0.023 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 35 0.023 gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 35 0.023 gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein... 35 0.023 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 35 0.023 gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Pl... 35 0.023 gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor rec... 34 0.030 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 34 0.039 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 34 0.039 gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X 34 0.039 gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modula... 33 0.051 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 33 0.051 gi|464541|sp|P35241|RADI_HUMAN Radixin 33 0.066 gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornif... 33 0.066 gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly ... 33 0.086 gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein... 33 0.086 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 33 0.086 gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain prot... 33 0.086 gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleo... 32 0.11 gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DN... 32 0.11 gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B 32 0.11 gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 32 0.11 gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like pr... 32 0.15 gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (His... 32 0.15 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 32 0.15 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 32 0.15 gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine rec... 32 0.15 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 32 0.15 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 32 0.15 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 32 0.19 gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myos... 32 0.19 gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin conden... 32 0.19 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 32 0.19 gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 31 0.25 gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein 31 0.25 gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,... 31 0.25 gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat p... 31 0.25 gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (C... 31 0.25 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 31 0.33 gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific pro... 31 0.33 gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precur... 31 0.33 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 31 0.33 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 31 0.33 gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi... 31 0.33 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 31 0.33 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 31 0.33 gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleo... 30 0.43 gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1... 30 0.43 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 30 0.43 gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate... 30 0.43 gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor 30 0.43 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 30 0.43 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 30 0.43 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 30 0.43 gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein ki... 30 0.43 gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL... 30 0.56 gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effecto... 30 0.56 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 30 0.56 gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily... 30 0.56 gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal... 30 0.56 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 30 0.73 gi|55976224|sp|O94972|TM37_HUMAN Tripartite motif protein 3... 30 0.73 gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding prot... 30 0.73 gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chai... 30 0.73 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 30 0.73 gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysac... 30 0.73 gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death prot... 30 0.73 gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain... 30 0.73 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 30 0.73 gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI 29 0.95 gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense tra... 29 0.95 gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting p... 29 0.95 gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skel... 29 0.95 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 29 0.95 gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-... 29 0.95 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 29 1.2 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 29 1.2 gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1... 29 1.2 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 29 1.2 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 29 1.2 gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (... 29 1.2 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 29 1.2 gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist... 28 1.6 gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 prot... 28 1.6 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 28 1.6 gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE fam... 28 1.6 gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclero... 28 1.6 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 28 1.6 gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense tra... 28 1.6 gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like pro... 28 1.6 gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-termin... 28 1.6 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 28 1.6 gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinas... 28 1.6 gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-... 28 1.6 gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein ... 28 2.1 gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Vi... 28 2.1 gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kD... 28 2.1 gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreduct... 28 2.1 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 28 2.1 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 28 2.1 gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia... 28 2.1 gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal... 28 2.8 gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting pro... 28 2.8 gi|135846|sp|P20962|PTMS_HUMAN Parathymosin 28 2.8 gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 3... 28 2.8 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 28 2.8 gi|13431957|sp|O60763|VDP_HUMAN General vesicular transport... 28 2.8 gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated prot... 28 2.8 gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin ... 28 2.8 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 28 2.8 gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) 28 2.8 gi|119360|sp|P14625|ENPL_HUMAN Endoplasmin precursor (94 kD... 27 3.6 gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal... 27 3.6 gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa parane... 27 3.6 gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M prote... 27 3.6 gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain pr... 27 3.6 gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled... 27 3.6 gi|13638422|sp|Q01538|MYT1_HUMAN Myelin transcription facto... 27 4.7 gi|18202499|sp|Q14331|FRG1_HUMAN FRG1 protein (FSHD region ... 27 4.7 gi|21759000|sp|Q12955|ANK3_HUMAN Ankyrin 3 (ANK-3) (Ankyrin G) 27 4.7 gi|38372394|sp|Q9NUV9|GIM4_HUMAN GTPase, IMAP family member... 27 4.7 gi|21431832|sp|O75683|SUR6_HUMAN Surfeit locus protein 6 27 4.7 gi|9297020|sp|Q13402|MYO7A_HUMAN Myosin VIIa 27 4.7 gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 4... 27 4.7 gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 ... 27 4.7 gi|45477011|sp|O75113|N4B1_HUMAN Nedd4-binding protein 1 (N... 27 4.7 gi|20137932|sp|Q9BXL6|CARE_HUMAN Caspase recruitment domain... 27 4.7 gi|20138768|sp|Q9NZM3|ITN2_HUMAN Intersectin 2 (SH3 domain-... 27 4.7 gi|547754|sp|P35908|K22E_HUMAN Keratin, type II cytoskeleta... 27 4.7 gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-... 27 4.7 gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskele... 27 4.7 gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentri... 27 4.7 gi|1706622|sp|P52732|KIF11_HUMAN Kinesin-like protein KIF11... 27 6.2 gi|48428133|sp|Q96M83|CCD7_HUMAN Coiled-coil domain contain... 27 6.2 gi|6707663|sp|P78363|ABCA4_HUMAN Retinal-specific ATP-bindi... 27 6.2 gi|20532406|sp|P17980|PRS6A_HUMAN 26S protease regulatory s... 27 6.2 gi|57015409|sp|Q8IWT3|PARC_HUMAN p53-associated parkin-like... 27 6.2 gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p1... 27 6.2 gi|30580600|sp|O00463|TRA5_HUMAN TNF receptor associated fa... 27 6.2 gi|20138891|sp|O75925|PIAS1_HUMAN Protein inhibitor of acti... 27 6.2 gi|12229723|sp|Q9ULD4|BRF3_HUMAN Bromodomain and PHD finger... 27 6.2 gi|47606762|sp|Q96MU7|YT521_HUMAN Putative splicing factor ... 26 8.1 gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonuc... 26 8.1 gi|6831676|sp|O15266|SHOX_HUMAN Short stature homeobox prot... 26 8.1 gi|2500771|sp|Q16181|SEPT7_HUMAN Septin 7 (CDC10 protein ho... 26 8.1 gi|22653670|sp|Q9UIG0|BAZ1B_HUMAN Bromodomain adjacent to z... 26 8.1 gi|47116932|sp|Q9NQ29|L7L1_HUMAN Putative RNA-binding prote... 26 8.1 gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein ty... 26 8.1 gi|125351|sp|P16591|FER_HUMAN Proto-oncogene tyrosine-prote... 26 8.1 gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (... 26 8.1 gi|13626094|sp|Q9UGM1|ACH9_HUMAN Neuronal acetylcholine rec... 26 8.1 gi|6166119|sp|O60879|DIAP2_HUMAN Diaphanous protein homolog... 26 8.1 gi|41017271|sp|O60237|MPT2_HUMAN Protein phosphatase 1 regu... 26 8.1 gi|20978544|sp|O00232|PSDC_HUMAN 26S proteasome non-ATPase ... 26 8.1 gi|41017595|sp|O95153|RIP1_HUMAN Peripheral-type benzodiaze... 26 8.1 gi|18202489|sp|Q12852|M3K12_HUMAN Mitogen-activated protein... 26 8.1 gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment facto... 26 8.1 gi|45645200|sp|Q92599|SEP8_HUMAN Septin 8 26 8.1 gi|14548075|sp|O14645|IDLC_HUMAN Axonemal dynein light inte... 26 8.1 gi|55976571|sp|Q96L91|EP400_HUMAN E1A binding protein p400 ... 26 8.1 gi|22653668|sp|Q9UIF8|BAZ2B_HUMAN Bromodomain adjacent to z... 26 8.1
>gi|54039751|sp|P67936|TPM4_HUMAN Tropomyosin alpha 4 chain (Tropomyosin 4) (TM30p1) Length = 248 Score = 200 bits (509), Expect = 2e-52 Identities = 123/246 (50%), Positives = 145/246 (58%), Gaps = 42/246 (17%) Query: 1 MAGIATMEEVKCKIQVLQQQADDXXXXXXXXXXXXXX----------------------- 37 MAG+ ++E VK KIQ LQQQAD+ Sbjct: 1 MAGLNSLEAVKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVE 60 Query: 38 ---DHAQERLTTALQKLXXXXXXXXXXXRDMK----------------EIQLKEAKHIAE 78 D AQERL TALQKL R MK E+QLKEAKHIAE Sbjct: 61 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAE 120 Query: 79 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQ 138 EADRKYEEV RKLVI+EG+LE EERAE++E +C + +E+++ + NLK L A EKYS+ Sbjct: 121 EADRKYEEVARKLVILEGELERAEERAEVSELKCGDLEEELKNVTNNLKSLEAASEKYSE 180 Query: 139 KEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 198 KED YEEEIK+L+DKLKEAETRAEF ER VAKLEKT DDLE KL KEEN+ + L Q Sbjct: 181 KEDKYEEEIKLLSDKLKEAETRAEFAERTVAKLEKTIDDLEEKLAQAKEENVGLHQTLDQ 240 Query: 199 TLLDLN 204 TL +LN Sbjct: 241 TLNELN 246
>gi|136085|sp|P06753|TPM3_HUMAN Tropomyosin alpha 3 chain (Tropomyosin 3) (Tropomyosin gamma) Length = 284 Score = 190 bits (482), Expect = 3e-49 Identities = 111/185 (60%), Positives = 121/185 (65%), Gaps = 16/185 (8%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMK----------------EIQLKEAKHIAEEAD 81 D AQERL TALQKL R MK EIQLKEAKHIAEEAD Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEAD 159 Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKED 141 RKYEEV RKLVIIEGDLE TEERAELAES+C E +E+++ + NLK L EKYSQKED Sbjct: 160 RKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKED 219 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLL 201 YEEEIKILTDKLKEAETRAEF ER VAKLEKT DDLE +L K + L L Sbjct: 220 KYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALN 279 Query: 202 DLNEM 206 D+ + Sbjct: 280 DMTSI 284
Score = 43.1 bits (100), Expect = 6e-05 Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 1/108 (0%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 144 E + +K+ +++ D E +RAE AE+ ++ +E+ + ++ L + + + D Y Sbjct: 2 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYS 61 Query: 145 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 192 E +K +KL+ AE +A E VA L + +E +L +E L T Sbjct: 62 EALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELD-RAQERLAT 108
Score = 33.5 bits (75), Expect = 0.051 Identities = 25/127 (19%), Positives = 62/127 (48%), Gaps = 14/127 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC-------TEERAELAESRCQETD 116 + E + K+A+ +++ + + + +KL E +L+ +E+ ELAE + + + Sbjct: 23 EQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAE 82 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 ++ +++ ++ + + + D +E + KL+EAE A+ +ER + +E Sbjct: 83 AEVASLNRRIQLVEE-------ELDRAQERLATALQKLEEAEKAADESERGMKVIENRAL 135 Query: 177 DLEYKLK 183 E K++ Sbjct: 136 KDEEKME 142
>gi|136092|sp|P09493|TPM1_HUMAN Tropomyosin 1 alpha chain (Alpha-tropomyosin) Length = 284 Score = 177 bits (449), Expect = 2e-45 Identities = 102/185 (55%), Positives = 117/185 (63%), Gaps = 16/185 (8%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMK----------------EIQLKEAKHIAEEAD 81 D AQERL TALQKL R MK EIQLKEAKHIAE+AD Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDAD 159 Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKED 141 RKYEEV RKLVIIE DLE EERAEL+E +C E +E+++ + NLK L EKYSQKED Sbjct: 160 RKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKED 219 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLL 201 YEEEIK+L+DKLKEAETRAEF ER V KLEK+ DDLE +L K + L L Sbjct: 220 RYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALN 279 Query: 202 DLNEM 206 D+ + Sbjct: 280 DMTSI 284
Score = 38.5 bits (88), Expect = 0.002 Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 144 + + +K+ +++ D E +RAE AE+ + +++ + ++ L L + + D Y Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYS 61 Query: 145 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 192 E +K +KL+ AE +A E VA L + +E +L +E L T Sbjct: 62 EALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELD-RAQERLAT 108
Score = 32.3 bits (72), Expect = 0.11 Identities = 26/122 (21%), Positives = 58/122 (47%), Gaps = 10/122 (8%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ---- 124 Q + K AE+ ++ E+ +LV ++ L+ TE+ + ++ E++ L ++ Sbjct: 24 QAEADKKAAEDRSKQLED---ELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATD 80 Query: 125 ---NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 ++ L+ + ++ D +E + KL+EAE A+ +ER + +E E K Sbjct: 81 AEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEK 140 Query: 182 LK 183 ++ Sbjct: 141 ME 142
>gi|136090|sp|P07951|TPM2_HUMAN Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin) Length = 284 Score = 173 bits (438), Expect = 4e-44 Identities = 97/185 (52%), Positives = 120/185 (64%), Gaps = 16/185 (8%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMK----------------EIQLKEAKHIAEEAD 81 D AQERL TALQKL R MK E+QLKEAKHIAE++D Sbjct: 100 DRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSD 159 Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKED 141 RKYEEV RKLVI+EG+LE +EERAE+AES+C + +E+++++ NLK L +KYS KED Sbjct: 160 RKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKED 219 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLL 201 YEEEIK+L +KLKEAETRAEF ER VAKLEKT DDLE ++ K + L L Sbjct: 220 KYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALN 279 Query: 202 DLNEM 206 D+ + Sbjct: 280 DITSL 284
Score = 45.4 bits (106), Expect = 1e-05 Identities = 34/115 (29%), Positives = 59/115 (51%), Gaps = 15/115 (13%) Query: 85 EEVPRKLVIIEGDLECTEERAELAES-------RCQETDEQIRLMDQNLKCLSDAEEKYS 137 + + +K+ +++ D E +RAE AE+ RC++ +E+ + + + LK D EKYS Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYS 61 Query: 138 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCT 192 E +K +KL++AE +A E VA L + +E +L +E L T Sbjct: 62 -------ESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELD-RAQERLAT 108
Score = 35.8 bits (81), Expect = 0.010 Identities = 23/120 (19%), Positives = 59/120 (49%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 + E K+A+ ++ + + + + +KL E ++E E + A+ + ++ +++ + Sbjct: 23 EQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAE 82 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 ++ L+ + ++ D +E + KL+EAE A+ +ER + +E E K++ Sbjct: 83 ADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKME 142
>gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smooth muscle isoform (SMMHC) Length = 1972 Score = 46.2 bits (108), Expect = 8e-06 Identities = 30/122 (24%), Positives = 61/122 (50%), Gaps = 2/122 (1%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E +L+E + ++ + +++ ++++ +E LE E + + + +I+ ++ + Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 + D K S++ + EE I LT L E E +A+ +L K E +LE +LK K Sbjct: 988 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK--K 1045 Query: 187 EE 188 EE Sbjct: 1046 EE 1047
Score = 35.0 bits (79), Expect = 0.017 Identities = 24/122 (19%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Query: 64 DMKEIQ--LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 D+ ++Q L A+ ++AD + EE+ +L ++ E+R + +E++ Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 N++ +SD K +Q+ + E+ ++ E+ + ER +L ++E Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807 Query: 182 LK 183 +K Sbjct: 1808 VK 1809
Score = 29.6 bits (65), Expect = 0.73 Identities = 37/192 (19%), Positives = 80/192 (41%), Gaps = 32/192 (16%) Query: 7 MEEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMK 66 MEE+K +++ L+ + + A+ RL +Q L + Sbjct: 1541 MEEMKTQLEELEDELQ-------------ATEDAKLRLEVNMQALKGQFERDLQARDEQN 1587 Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVI-------IEGDLECTEERAELAESRCQETDEQI 119 E + ++ + E + + E+ ++ + +EGDL+ E +A+ A +E +Q+ Sbjct: 1588 EEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL 1647 Query: 120 RLMDQNLKCLS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 R + +K + E+ + +++I+ KE E +A+ E A L + +DL Sbjct: 1648 RKLQAQMKDFQRELEDARASRDEIFA--------TAKENEKKAKSLE---ADLMQLQEDL 1696 Query: 179 EYKLKCNKEENL 190 + K+ +L Sbjct: 1697 AAAERARKQADL 1708
Score = 26.9 bits (58), Expect = 4.7 Identities = 28/163 (17%), Positives = 67/163 (41%), Gaps = 13/163 (7%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMKEI------QLKEAKHIAEEADRKYEEVPRKL 91 +H +++L +Q+L ++ + +++ + EA+ K ++ + + Sbjct: 1251 EHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310 Query: 92 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILT 151 + L+ T+E + + ++R +++ L D ++ + + E I L Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370 Query: 152 DKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE-ENLCTQ 193 +L +++ + + V LE E K + KE ENL Q Sbjct: 1371 IQLSDSKKKLQDFASTVEALE------EGKKRFQKEIENLTQQ 1407
Score = 26.2 bits (56), Expect = 8.1 Identities = 27/123 (21%), Positives = 51/123 (41%), Gaps = 8/123 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYE-EVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 R E Q KE + E + + + + +E + EE+ E Q + ++ Sbjct: 1787 RQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ 1846 Query: 122 MDQNLK-CLSDAE------EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 D+ LK L E E+Y ++ + +K L +L+EAE ++ KL++ Sbjct: 1847 KDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906 Query: 175 TDD 177 D+ Sbjct: 1907 LDE 1909
>gi|13431722|sp|Q9Y4I1|MYO5A_HUMAN Myosin Va (Myosin 5A) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin) Length = 1855 Score = 43.9 bits (102), Expect = 4e-05 Identities = 37/158 (23%), Positives = 73/158 (46%), Gaps = 22/158 (13%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEG--------------DLECTEERAELAESRC 112 E ++ + + +E ++ Y+ + KL +EG L+ +EE A++A R Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985 Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAET-----RAEFTERL 167 E+I + ++L+ ++ + D Y++E + L LKE T + R+ Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045 Query: 168 VAKLEKTTDDLEYKL---KCNKEENLCTQRMLYQTLLD 202 V + ++ T+ +E KL E +L +R+ YQ LL+ Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLN 1083
Score = 26.9 bits (58), Expect = 4.7 Identities = 29/135 (21%), Positives = 56/135 (41%), Gaps = 18/135 (13%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRC----QETDEQI 119 D++ +QL E + A+ A + + ++ + DLE T + E QET++ + Sbjct: 967 DLERLQLSEEE--AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLV 1024 Query: 120 RLMDQ------------NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL 167 + + N + + A+E E EE K L L + R + Sbjct: 1025 SNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNE 1084 Query: 168 VAKLEKTTDDLEYKL 182 ++LE+ DDL+ ++ Sbjct: 1085 FSRLEERYDDLKEEM 1099
>gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein (Centromere protein F) (Mitosin) (AH antigen) Length = 3210 Score = 43.5 bits (101), Expect = 5e-05 Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 9/138 (6%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 QLKE++H A+ + E + R+L I + E AE ++ + +I M Q+L+ Sbjct: 2419 QLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRG 2478 Query: 129 LS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 L D S+KED LT++L++ + R E + + E + E + KE Sbjct: 2479 LELDVVTIRSEKED--------LTNELQKEQERISELEIINSSFENILQEKEQEKVQMKE 2530 Query: 188 ENLCTQRMLYQTLLDLNE 205 ++ ML L +LNE Sbjct: 2531 KSSTAMEMLQTQLKELNE 2548
Score = 39.7 bits (91), Expect = 7e-04 Identities = 30/142 (21%), Positives = 67/142 (47%), Gaps = 3/142 (2%) Query: 67 EIQLKEAKHIAE---EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 E K+ HIAE E +R+ + + K+ +E +L+ +EE EL + + ++ + Sbjct: 2225 EADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLK 2284 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 ++ ++ + + + E + LT +++E + + ++L++ + ++ E Sbjct: 2285 TQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEI 2344 Query: 184 CNKEENLCTQRMLYQTLLDLNE 205 KEE+ ML L +LNE Sbjct: 2345 QIKEESKTAVEMLQNQLKELNE 2366
Score = 32.7 bits (73), Expect = 0.086 Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 5/122 (4%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 137 ++A KY + +KL + DL C + AE A RC +++I+ ++ + +++ Sbjct: 351 DQASTKYTALEQKLKKLTEDLSCQRQNAESA--RC-SLEQKIKEKEKEFQEELSRQQRSF 407 Query: 138 QKEDIYEEEIKI-LTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRML 196 Q D ++K LT +L++A+ + + KL LE L+ K++ LC Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK-LCRAEQA 466 Query: 197 YQ 198 +Q Sbjct: 467 FQ 468
Score = 32.3 bits (72), Expect = 0.11 Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 20/169 (11%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQ--LKEAKHIAEEADRKYEEVPRKLVIIEGDL 98 +E+LT+ + L +E+ LK I EE + + + + ++ + Sbjct: 2825 REKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKEN 2884 Query: 99 ECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK------YSQKEDIYEEEIKILTD 152 E + + +L C++ +E+ ++ + L L A+EK K D EIK L + Sbjct: 2885 ERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKE 2944 Query: 153 KLKEAETRA-EFTERLVA------KLEKTTDDLEYKLKCNKEENLCTQR 194 L+E A E+ ++ + KLEK + LE ++ +LC+Q+ Sbjct: 2945 TLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQV-----AHLCSQQ 2988
Score = 30.8 bits (68), Expect = 0.33 Identities = 33/144 (22%), Positives = 56/144 (38%), Gaps = 12/144 (8%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELAESRCQETDEQIRLM 122 +M + QLKE E K + +EC E E+A+L + E ++ Sbjct: 2537 EMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQG-LDEAKNNYIVL 2595 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEI----------KILTDKLKEAETRAEFTERLVAKLE 172 ++ L E QK + +EEI + L KL + E + + +L Sbjct: 2596 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELR 2655 Query: 173 KTTDDLEYKLKCNKEENLCTQRML 196 T +LE K++ + +N Q L Sbjct: 2656 NLTVELEQKIQVLQSKNASLQDTL 2679
Score = 30.8 bits (68), Expect = 0.33 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 12/112 (10%) Query: 63 RDMKEIQLKE-AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 ++ EIQ+KE +K E + +E+ + + GD E + + + +E + Q+R Sbjct: 2339 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE-EHQLRN 2397 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 + L+ +A+EK +++ +L +LKE+E A+ + V LE+ Sbjct: 2398 SIEKLRARLEADEK---------KQLCVL-QQLKESEHHADLLKGRVENLER 2439
Score = 26.6 bits (57), Expect = 6.2 Identities = 27/132 (20%), Positives = 57/132 (43%), Gaps = 3/132 (2%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAE 133 K I+E +D+ +E KL++++ E +L++ ++ +L +C S E Sbjct: 1009 KSISELSDQYKQE---KLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCE 1065 Query: 134 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQ 193 + ++ E + E K + L + E + L+ +LE L ++ N+ + Sbjct: 1066 NRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEA 1125 Query: 194 RMLYQTLLDLNE 205 L Q ++ L E Sbjct: 1126 GGLKQEIMTLKE 1137
Score = 26.2 bits (56), Expect = 8.1 Identities = 22/105 (20%), Positives = 51/105 (48%), Gaps = 8/105 (7%) Query: 94 IEGDLECTEERA----ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKI 149 + G+L+ ++ +L+E ++T E + L C+ AE + +K ++ + Sbjct: 2059 LRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSD 2118 Query: 150 LTDKLKE---AETRAEFTERLVAKLEKTTDDLEYKL-KCNKEENL 190 +++ LK+ + + + E+ L T +LE ++ + NKE+ L Sbjct: 2119 VSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2163
>gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta) Length = 1935 Score = 42.4 bits (98), Expect = 1e-04 Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 14/126 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 ++ + +L+E + + E+ +R RKL E +L T ER +L S+ Q + MD Sbjct: 1679 NLLQAELEELRAVVEQTERS-----RKLA--EQELIETSERVQLLHSQNTSLINQKKKMD 1731 Query: 124 QNLKCL-SDAEEKYSQKEDIYEEEIKILTD------KLKEAETRAEFTERLVAKLEKTTD 176 +L L ++ EE + + E+ K +TD +LK+ + + ER+ +E+T Sbjct: 1732 ADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK 1791 Query: 177 DLEYKL 182 DL+++L Sbjct: 1792 DLQHRL 1797
Score = 42.4 bits (98), Expect = 1e-04 Identities = 30/117 (25%), Positives = 56/117 (47%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+ + + E+ + ++ R +EGDL+ T+E E+ Q+ DE+++ D L Sbjct: 1028 EQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFEL 1087 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L+ E ++++K L +++E E E AK+EK DL +L+ Sbjct: 1088 NALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELE 1144
Score = 35.4 bits (80), Expect = 0.013 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE E+ + E+ K +E EC+E + ++ E T+ Sbjct: 916 EAKVKEMNERLEDEEEMNAELTAKKRKLED--ECSELKRDIDDLELTLAKVEKEKHATEN 973 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 974 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDD 1033 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1034 LEGSLEQEKKVRMDLER 1050
Score = 32.3 bits (72), Expect = 0.11 Identities = 35/141 (24%), Positives = 62/141 (43%), Gaps = 24/141 (17%) Query: 65 MKEIQ--LKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEER-------AELAESRCQE 114 +K++Q L EA+ IA + +K +++ ++ +E +LE ++R +E R +E Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKE 1849 Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETR 160 Q +NL L D +K K Y+ + + + +L EAE R Sbjct: 1850 LTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER 1909 Query: 161 AEFTERLVAKLEKTTDDLEYK 181 A+ E V KL + D+ K Sbjct: 1910 ADIAESQVNKLRAKSRDIGTK 1930
Score = 31.6 bits (70), Expect = 0.19 Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 6/130 (4%) Query: 65 MKE--IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLE----CTEERAELAESRCQETDEQ 118 MKE +LKEA +E ++ EE L+ + DL+ ++ AE RC + + Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKN 911 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 ++ +K +++ E + + + L D+ E + + E +AK+EK Sbjct: 912 KIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHAT 971 Query: 179 EYKLKCNKEE 188 E K+K EE Sbjct: 972 ENKVKNLTEE 981
Score = 30.4 bits (67), Expect = 0.43 Identities = 16/48 (33%), Positives = 29/48 (60%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 111 D ++++K K AEEA+ + K ++ +L+ EERA++AES+ Sbjct: 1869 DKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916
Score = 30.4 bits (67), Expect = 0.43 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 QL++ K EE + + L D + E+ E +ET+ + L K Sbjct: 1311 QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE------EETEAKAELQRVLSKA 1364 Query: 129 LSDAEE---KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 S+ + KY Q+ + EE K L +L+EAE E + LEKT L+ + Sbjct: 1365 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424 Query: 182 LK 183 ++ Sbjct: 1425 IE 1426
>gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha) Length = 1939 Score = 41.6 bits (96), Expect = 2e-04 Identities = 34/126 (26%), Positives = 64/126 (50%), Gaps = 14/126 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 ++ + +L+E + + E+ +R RKL E +L T ER +L S+ Q + M+ Sbjct: 1681 NLLQAELEELRAVVEQTERS-----RKLA--EQELIETSERVQLLHSQNTSLINQKKKME 1733 Query: 124 QNLKCL-SDAEEKYSQKEDIYEEEIKILTD------KLKEAETRAEFTERLVAKLEKTTD 176 +L L S+ EE + + E+ K +TD +LK+ + + ER+ +E+T Sbjct: 1734 ADLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK 1793 Query: 177 DLEYKL 182 DL+++L Sbjct: 1794 DLQHRL 1799
Score = 39.7 bits (91), Expect = 7e-04 Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 24/148 (16%) Query: 65 MKEIQ--LKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEER-------AELAESRCQE 114 +K++Q L EA+ IA + +K +++ ++ +EG+LE ++R +E R +E Sbjct: 1792 IKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKE 1851 Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETR 160 Q +NL L D +K K Y+ + + + +L EAE R Sbjct: 1852 LTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER 1911 Query: 161 AEFTERLVAKLEKTTDDLEYKLKCNKEE 188 A+ E V KL + D+ K K + EE Sbjct: 1912 ADIAESQVNKLRAKSRDIGAKQKMHDEE 1939
Score = 35.0 bits (79), Expect = 0.017 Identities = 28/137 (20%), Positives = 60/137 (43%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE E+ + E+ K +E EC+E + ++ E T+ Sbjct: 918 EAKVKEMNERLEDEEEMNAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 975 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 976 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1036 LEGSLEQEKKVRMDLER 1052
Score = 30.4 bits (67), Expect = 0.43 Identities = 16/48 (33%), Positives = 29/48 (60%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 111 D ++++K K AEEA+ + K ++ +L+ EERA++AES+ Sbjct: 1871 DKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1918
Score = 30.0 bits (66), Expect = 0.56 Identities = 29/131 (22%), Positives = 59/131 (45%), Gaps = 8/131 (6%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLE----CTEERAELAESRCQETDE 117 MKE + K E+++ + +E+ K+V + + DL+ ++ AE RC + + Sbjct: 854 MKE-EFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIK 912 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 ++ +K +++ E + + + L D+ E + + E +AK+EK Sbjct: 913 NKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 972 Query: 178 LEYKLKCNKEE 188 E K+K EE Sbjct: 973 TENKVKNLTEE 983
Score = 29.3 bits (64), Expect = 0.95 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 13/122 (10%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q+++ K EE + + L D + E+ E +ET+ + L K Sbjct: 1313 QMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYE------EETEAKAELQRVLSKA 1366 Query: 129 LSDAEE---KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 S+ + KY Q+ + EE K L +L++AE E + LEKT L+ + Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE 1426 Query: 182 LK 183 ++ Sbjct: 1427 IE 1428
>gi|48428109|sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein (ATM and Rad3 related interacting protein) Length = 791 Score = 41.6 bits (96), Expect = 2e-04 Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD 97 DH RL + K +D E+++ +A++ +E K + + +++I G+ Sbjct: 84 DHKVHRLLDGMSKNPSGKNRETVPIKDNFELEVLQAQY--KELKEKMKVMEEEVLIKNGE 141 Query: 98 LECTEERAELAESRCQETDEQIRLMDQN-LKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 156 ++ + ES +E L++Q + LSD E+++S+K + E++ ++ E Sbjct: 142 IKILRDSLHQTESVLEEQRRSHFLLEQEKTQALSDKEKEFSKKLQSLQSELQFKDAEMNE 201 Query: 157 AETRAEFTER 166 T+ + +ER Sbjct: 202 LRTKLQTSER 211
>gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of chromosome 2-like 1 protein (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) (PRO0324) Length = 1197 Score = 41.2 bits (95), Expect = 2e-04 Identities = 31/150 (20%), Positives = 65/150 (43%), Gaps = 20/150 (13%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGD-----------LECTEERAELAESRCQET 115 E LK K I +A+ KYE + K+ E + L+C + +A+ + + +E Sbjct: 756 EETLKNTKEIQRKAEEKYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEK 815 Query: 116 DEQIRLMDQNLKCLSDAEEKYSQKEDI-------YEEEIKILTDKLKEAETRAEFTERLV 168 +++ + L+ L Y Q+ + YE +I+++ ++ + + + V Sbjct: 816 QQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEV 875 Query: 169 AKLEK--TTDDLEYKLKCNKEENLCTQRML 196 K ++ T D KL K +N ++ M+ Sbjct: 876 TKQKEVITAQDTVIKLNMQKWQNTRSKTMI 905
Score = 34.7 bits (78), Expect = 0.023 Identities = 32/126 (25%), Positives = 60/126 (47%), Gaps = 16/126 (12%) Query: 67 EIQLKEAKHIA-EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD--EQIRLMD 123 E+++KE + A EE + K ++ E E A+L +++ Q++ +Q +D Sbjct: 687 ELRIKENELRALEEELAGLKNTAEKYRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELD 746 Query: 124 QNLKCLSDAEEKYSQKEDIY---EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 K + ++EE ++I EE+ ++L +K+K AE A+ E+ D + Sbjct: 747 ALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMKNAE----------AERERELKDAQK 796 Query: 181 KLKCNK 186 KL C K Sbjct: 797 KLDCAK 802
Score = 28.5 bits (62), Expect = 1.6 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 9/107 (8%) Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQK-- 139 ++ ++V +L I E +L EE ELA + T E+ R + Q + ++ + K Sbjct: 679 QELKDVQDELRIKENELRALEE--ELAGLK--NTAEKYRQLKQQWEMKTEEADLLQTKLQ 734 Query: 140 EDIY---EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 + Y +EE+ L ++E+E + T+ + K E+ + LE K+K Sbjct: 735 QSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEEKYEVLENKMK 781
Score = 26.9 bits (58), Expect = 4.7 Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 9/126 (7%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D ++KE + E + EE+ R+ + LE E + ES+ + ++ Sbjct: 806 DASSKKMKEKQQEVEAITLELEELKREHTSYKQQLEAVNEAIKSYESQIEVMAAEVA--- 862 Query: 124 QNLKCLSDAEEKYS-QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 +N + ++ A+E+ + QKE I ++ I + K TR++ T L K++ +L++ + Sbjct: 863 KNKESVNKAQEEVTKQKEVITAQDTVIKLNMQKWQNTRSK-TMILSLKIK----ELDHHI 917 Query: 183 KCNKEE 188 +K E Sbjct: 918 SKHKRE 923
>gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motility receptor (Intracellular hyaluronic acid binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen) Length = 724 Score = 41.2 bits (95), Expect = 2e-04 Identities = 27/123 (21%), Positives = 62/123 (50%), Gaps = 3/123 (2%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 KE + + E + + + + +K ++ + + E +++ +S Q+ E + Q Sbjct: 300 KEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQK 359 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 L +E+ ++++++EEE+K D+L + + + E ERLV +LE+ +LK Sbjct: 360 L---CSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLL 416 Query: 186 KEE 188 +E+ Sbjct: 417 EEK 419
Score = 39.7 bits (91), Expect = 7e-04 Identities = 37/131 (28%), Positives = 66/131 (50%), Gaps = 9/131 (6%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE-RAELAESRCQETDEQIR---LM 122 E+Q + K I E+ +R E++ +K + I+ L+ +E + L + C +E ++ L Sbjct: 317 EMQNLKQKFILEQQER--EKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLF 374 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 ++ LK D +K QKE+ E +K L + EA++RAE + L KL+ +LE Sbjct: 375 EEELKQTLDELDKLQQKEEQAERLVKQLEE---EAKSRAEELKLLEEKLKGKEAELEKSS 431 Query: 183 KCNKEENLCTQ 193 + + L Q Sbjct: 432 AAHTQATLLLQ 442
Score = 34.3 bits (77), Expect = 0.030 Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 14/122 (11%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E++L+ + EE+ K ++ KLV IE E +E++E T++ + +++ + Sbjct: 192 EMKLQVTQRSLEESQGKIAQLEGKLVSIEK--EKIDEKSE--------TEKLLEYIEE-I 240 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 C SD EKY EE +K +K E + + E + L K +DL K + + Sbjct: 241 SCASDQVEKYKLDIAQLEENLK---EKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLE 297 Query: 187 EE 188 +E Sbjct: 298 KE 299
>gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin Length = 1898 Score = 40.4 bits (93), Expect = 4e-04 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 18/148 (12%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE---RAELAESRCQETDEQI 119 R K++Q KE + + EE +++ + K E +L+ EE R E + R QE + Q Sbjct: 978 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1037 Query: 120 RLMDQ-------------NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTER 166 R D+ + L + E +Y ++E++ +EE ++L ++ +E R E ER Sbjct: 1038 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE-RETRRRQEL-ER 1095 Query: 167 LVAKLEKTTDDLEYKLKCNKEENLCTQR 194 K E+ + E L+ E+ +R Sbjct: 1096 QYRKEEELQQEEEQLLREEPEKRRRQER 1123
Score = 37.4 bits (85), Expect = 0.004 Identities = 36/156 (23%), Positives = 75/156 (48%), Gaps = 7/156 (4%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC 100 QE+L Q L R+ + Q +E ++ EE ++ EE +L+ E + Sbjct: 913 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE---QLLREEREKRR 969 Query: 101 TEERAEL--AESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 +ER + + Q+ +EQ+ + + + E+KY ++E++ +EE ++L ++ +E Sbjct: 970 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE-REKR 1028 Query: 159 TRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 194 R E+ ER K ++ + E L+ +E+ +R Sbjct: 1029 RRQEW-ERQYRKKDELQQEEEQLLREEREKRRLQER 1063
Score = 35.0 bits (79), Expect = 0.017 Identities = 36/134 (26%), Positives = 64/134 (47%), Gaps = 4/134 (2%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELAESRCQETDEQIRLMDQ 124 KE + +E EE + EE R+ + E + + + ER EL R +E +Q RL + Sbjct: 244 KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303 Query: 125 NLKCLSDAEEKYSQKEDIYE-EEIKILTDKLKEAETRAEFTERLVAKL--EKTTDDLEYK 181 EE+ Q+E+ E +E + ++ +E + R E ER +L E+ + E + Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363 Query: 182 LKCNKEENLCTQRM 195 L+ +EE Q++ Sbjct: 364 LRREQEEERREQQL 377
Score = 32.7 bits (73), Expect = 0.086 Identities = 25/127 (19%), Positives = 57/127 (44%), Gaps = 11/127 (8%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R E Q ++ + + +E ++ E P K E + +C E E Q+ +EQ+ Sbjct: 1090 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE------EEELQQEEEQLLRE 1143 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 ++ + + E +Y ++E++ ++ K + ++ + R++ + + E D K+ Sbjct: 1144 EREKRRRQELERQYREEEELQRQKRK---QRYRDEDQRSDLKWQWEPEKENAVRD--NKV 1198 Query: 183 KCNKEEN 189 C EN Sbjct: 1199 YCKGREN 1205
Score = 32.7 bits (73), Expect = 0.086 Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 11/136 (8%) Query: 63 RDMKEIQLKEAKHIAEEADR----KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ 118 R +E + ++ K EE R K EE R+ + + E+ E E R + +E+ Sbjct: 485 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 544 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYE----EEIKILTDKLKEAETRAEFTERLVAKLEKT 174 RL Q L+ S+ + + Q+E + + EE K L + +E + E ER L++ Sbjct: 545 ERLQ-QRLR--SEQQLRREQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 601 Query: 175 TDDLEYKLKCNKEENL 190 + + +LK +EE L Sbjct: 602 EERRQQRLKREQEERL 617
Score = 30.8 bits (68), Expect = 0.33 Identities = 28/130 (21%), Positives = 62/130 (47%), Gaps = 3/130 (2%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R+ K+ Q +E + + + + E R+ V+ + + + EE + + QE +EQ+R + Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKL 281 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEI--KILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 ++ EE+ Q+ E+++ K ++ ++ E R E ER + E+ L Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341 Query: 181 KLKCNKEENL 190 + + +E+ L Sbjct: 342 EQEERREQQL 351
Score = 28.9 bits (63), Expect = 1.2 Identities = 24/105 (22%), Positives = 51/105 (48%), Gaps = 12/105 (11%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELA-----ESRCQETDE 117 R+ + +Q +E ++ EE ++ EE + G+ T R EL E Q+ +E Sbjct: 1055 REKRRLQERERQYREEEELQQEEEQ------LLGEERETRRRQELERQYRKEEELQQEEE 1108 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 Q+ + + + E + ++E++ +EE ++L ++ +E R E Sbjct: 1109 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREE-REKRRRQE 1152
Score = 28.1 bits (61), Expect = 2.1 Identities = 31/152 (20%), Positives = 64/152 (42%), Gaps = 27/152 (17%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR--CQETDE------ 117 ++ +L+E K +E +RK+ E ++L EG + +E + E QE +E Sbjct: 1535 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQEDRKFREDEQLLQEREEQQLHRQ 1594 Query: 118 -----------QIRLMDQNLKCLSDAEEKYSQKEDIYEE--------EIKILTDKLKEAE 158 Q+R ++ + D + K+ ++E + +E + + + +E + Sbjct: 1595 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1654 Query: 159 TRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 R + ER + E+ E + K +EE L Sbjct: 1655 LRRQERERKFLQEEQQLRRQELERKFREEEQL 1686
Score = 27.7 bits (60), Expect = 2.8 Identities = 31/131 (23%), Positives = 54/131 (41%), Gaps = 2/131 (1%) Query: 66 KEIQLKEAKHIAEEAD-RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 +E QL+ + + E R+ +++ R+ + + +ER E R QE ++ Sbjct: 422 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 481 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC 184 + K K D EEE + KL+E E R + R + + E +LK Sbjct: 482 ETERHEQERRKQQLKRD-QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 540 Query: 185 NKEENLCTQRM 195 +EE QR+ Sbjct: 541 QEEEERLQQRL 551
>gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal muscle, perinatal (MyHC-perinatal) Length = 1937 Score = 40.0 bits (92), Expect = 5e-04 Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 35/148 (23%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAELAESRCQET 115 LKE + ++A R E++ +L I+E LE TE ++AE + Sbjct: 1653 LKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDA 1712 Query: 116 DEQIRLMD-QNLKCL--------------SDAEEKYSQKEDIYEEEIKILTD------KL 154 E+++L+ QN + S+ EE + + E+ K +TD +L Sbjct: 1713 SERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL 1772 Query: 155 KEAETRAEFTERLVAKLEKTTDDLEYKL 182 K+ + + ER+ LE+T DL+++L Sbjct: 1773 KKEQDTSAHLERMKKNLEQTVKDLQHRL 1800
Score = 40.0 bits (92), Expect = 5e-04 Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE AEE + E+ K +E EC+E + ++ E T+ Sbjct: 919 EAKIKEVTERAEEEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 976 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K S+++ +E + D L+ E + + KLE+ DD Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1037 LEGSLEQEKKLRMDLER 1053
Score = 34.7 bits (78), Expect = 0.023 Identities = 28/117 (23%), Positives = 52/117 (44%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ DE++ + + Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L E E +++IK L +++E E AK EK DL +L+ Sbjct: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELE 1147
Score = 33.5 bits (75), Expect = 0.051 Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 1/116 (0%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL-K 127 Q++E KH EE + + L D + E+ E + E + + + + Sbjct: 1314 QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ 1373 Query: 128 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 + E Q+ + EE K L +L+EAE E A LEKT L+ +++ Sbjct: 1374 WRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
Score = 31.6 bits (70), Expect = 0.19 Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 24/142 (16%) Query: 65 MKEIQ--LKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQE 114 +K++Q L EA+ +A + +K +++ ++ +EG++E ++R A E R +E Sbjct: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852 Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETR 160 Q +N+ L D +K K Y+ + + L +L+EAE R Sbjct: 1853 LTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEER 1912 Query: 161 AEFTERLVAKLEKTTDDLEYKL 182 A+ E V KL + ++ K+ Sbjct: 1913 ADIAESQVNKLRVKSREVHTKI 1934
Score = 30.8 bits (68), Expect = 0.33 Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 14/134 (10%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVII-----EGDLECTEERAELA--ESRCQETDE 117 MKE + ++ K +++ K +E+ K+V + + L+ E LA E RC++ + Sbjct: 855 MKE-EFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIK 913 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLEKT 174 ++ +K + E+ ++E+I E + + L D+ E + + E +AK+EK Sbjct: 914 NKIQLEAKIK---EVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 970 Query: 175 TDDLEYKLKCNKEE 188 E K+K EE Sbjct: 971 KHATENKVKNLTEE 984
Score = 30.4 bits (67), Expect = 0.43 Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 111 D + ++K K AEEA+ + K ++ +LE EERA++AES+ Sbjct: 1872 DKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQ 1919
>gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skeletal muscle, extraocular (MyHC-eo) Length = 1938 Score = 40.0 bits (92), Expect = 5e-04 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 9/102 (8%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS---DAEEKYSQKED 141 E RKL EGDL+ ++E E+ Q+ +E+++ + L L D E+ +S + Sbjct: 1053 ERAKRKL---EGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQ-- 1107 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 ++++IK L +++E E E L AK+EK DL +L+ Sbjct: 1108 -FQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELE 1148
Score = 39.7 bits (91), Expect = 7e-04 Identities = 26/119 (21%), Positives = 56/119 (47%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 +L+E + + E K + K ++ D++ E E T+ +++ + + + Sbjct: 929 RLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTA 988 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 L + K ++++ +E + D L+ E + ++ AKLE+ TDDLE L+ K+ Sbjct: 989 LEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKK 1047
Score = 39.3 bits (90), Expect = 0.001 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 35/149 (23%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEG--------------DLECTEERAELAESRCQE 114 QLK+++ ++A R E++ +L I+E LE TE L+E + Sbjct: 1653 QLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLD 1712 Query: 115 TDEQIRLM-DQN--------------LKCLSDAEEKYSQKEDIYEEEIKILTD------K 153 ++++L+ QN +C ++ E + + E+ K +TD + Sbjct: 1713 ASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEE 1772 Query: 154 LKEAETRAEFTERLVAKLEKTTDDLEYKL 182 LK+ + + ER+ LE+T DL+++L Sbjct: 1773 LKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Score = 38.5 bits (88), Expect = 0.002 Identities = 38/132 (28%), Positives = 66/132 (50%), Gaps = 28/132 (21%) Query: 83 KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI--RLMDQN---------LKCLSD 131 K E +++ ++ D E T+E +E+R +E +E++ L ++N + L D Sbjct: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904 Query: 132 AEEKYS---QKEDIYEEEIKILTDKLKEAETRAEFTERLVAK----------LEKTTDDL 178 AEE+ + + + E ++K LT++L+E E E LVAK L++ DDL Sbjct: 905 AEERCEGLIKSKILLEAKVKELTERLEEEE---EMNSELVAKKRNLEDKCSSLKRDIDDL 961 Query: 179 EYKL-KCNKEEN 189 E L K KE++ Sbjct: 962 ELTLTKVEKEKH 973
Score = 32.3 bits (72), Expect = 0.11 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 7/115 (6%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 QL+E K EE + + L D + E+ E E + + + Q L N + Sbjct: 1315 QLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE- 1371 Query: 129 LSDAEEKYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 ++ + KY Q+ + EE K L +L+EAE + E A LEKT L+ Sbjct: 1372 VAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQ 1426
Score = 30.0 bits (66), Expect = 0.56 Identities = 33/174 (18%), Positives = 72/174 (41%), Gaps = 9/174 (5%) Query: 40 AQERLTTALQKLXXXXXXXXXXXRDMKEIQ--LKEAKHIAEEADRKYEEVPRKLVIIEGD 97 A+E+ TA K +++++ L+ + D+K + L + Sbjct: 1404 AEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQK 1463 Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK---- 153 L+ ++ E A+ + ++ M + + D E ++ +EEI LT++ Sbjct: 1464 LDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAET 1523 Query: 154 ---LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 204 L+EAE + E+ + L+ +++E L+ + + L Q L Q +L+ Sbjct: 1524 GKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELD 1577
Score = 29.3 bits (64), Expect = 0.95 Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 2/126 (1%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R +E+ EA+ +E + K + ++ ++ ++ E AE RC+ + L+ Sbjct: 862 RTKEELARSEARR--KELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILL 919 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 + +K L++ E+ + + + L DK + + E + K+EK E K+ Sbjct: 920 EAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKV 979 Query: 183 KCNKEE 188 K EE Sbjct: 980 KNLSEE 985
Score = 27.3 bits (59), Expect = 3.6 Identities = 15/48 (31%), Positives = 27/48 (56%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESR 111 D + ++K K AEEA+ + + ++ +LE ERA++AES+ Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQ 1920
>gi|38604765|sp|Q86YM7|HOM1_HUMAN Homer protein homolog 1 Length = 354 Score = 40.0 bits (92), Expect = 5e-04 Identities = 35/129 (27%), Positives = 62/129 (48%), Gaps = 19/129 (14%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 137 EEA+R ++ V +LEC +A + E ++ I+ +++ LK + E+ Sbjct: 220 EEAERLHKRVT--------ELECVSSQANAVHTHKTELNQTIQELEETLKLKEEEIERLK 271 Query: 138 QKED---IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 194 Q+ D +E+ LT KL+E E R + LE DLE +L+ ++ E + Sbjct: 272 QEIDNARELQEQRDSLTQKLQEVEIRNK-------DLEGQLSDLEQRLEKSQNEQEAFRN 324 Query: 195 MLYQTLLDL 203 L +TLL++ Sbjct: 325 NL-KTLLEI 332
>gi|20139283|sp|Q9UL16|NESG_HUMAN Nasopharyngeal epithelium specific protein 1 Length = 386 Score = 40.0 bits (92), Expect = 5e-04 Identities = 41/153 (26%), Positives = 77/153 (50%), Gaps = 17/153 (11%) Query: 65 MKEIQLKEAKHIAEEADRKYEE--VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 M E++ +++ EE +RK E + + I+E + EER+ LAE R QE ++ + M Sbjct: 93 MMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYM 152 Query: 123 DQ-NLKCLSDAEEKYSQKEDIYEEEIKILTD--KLKEAETRA----------EFTERLVA 169 +Q + L D E + QK + + EIK + D + ++AE A EFT++ +A Sbjct: 153 EQLQEEDLKDMERRQQQKLKM-QAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMA 211 Query: 170 KLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 202 + E + + +++ KE+ + R + + D Sbjct: 212 R-EAEFEAEQERIRREKEKEIARLRAMQEKAQD 243
>gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (SB1.8/DXS423E protein) (Sb1.8) Length = 1233 Score = 39.7 bits (91), Expect = 7e-04 Identities = 29/120 (24%), Positives = 64/120 (53%), Gaps = 8/120 (6%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD----EQIR 120 ++E Q+K+ + EEA ++ + ++L D + ++R +L E + ET+ +++R Sbjct: 367 LEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLR 426 Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKI---LTDKLKEAETRA-EFTERLVAKLEKTTD 176 +++N K + EE + + EE+ K+ LT++++ A+ R E + L +E+ D Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGD 486
Score = 28.5 bits (62), Expect = 1.6 Identities = 22/117 (18%), Positives = 53/117 (45%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R ++QL + H E ++ +E+ K IE D + ++ + + + +E + +R Sbjct: 218 RAQVQLQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQ 277 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 Q K + + + + +QK Y + + + K+K+ E + + +K D++ Sbjct: 278 QQIEKEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMD 334
>gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmuscle type B (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 39.7 bits (91), Expect = 7e-04 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 8/132 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKY--EEVPRKLVIIEGDLECTEERAELAESRCQ----ETD 116 ++++EI + EE +R + +K+ DLE + E A + Q + Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAE 977 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 +I+ M++ + L D K+ +++ + E+ I + +L E E +A+ ++ K E Sbjct: 978 AKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS 1037 Query: 177 DLEYKLKCNKEE 188 DLE +LK KEE Sbjct: 1038 DLEERLK--KEE 1047
Score = 38.5 bits (88), Expect = 0.002 Identities = 35/194 (18%), Positives = 80/194 (41%), Gaps = 25/194 (12%) Query: 8 EEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKE 67 +E+ C+++VLQQ + +H +++L +Q+L ++ E Sbjct: 1234 KELACEVKVLQQVKAES-------------EHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280 Query: 68 I------QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 +L + EEA++K + + +E L+ T+E + + +IR Sbjct: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 +++ L + +E+ + E+++ L +L + + + + + LE E K Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE------EAK 1394 Query: 182 LKCNKEENLCTQRM 195 K K+ +QR+ Sbjct: 1395 KKLLKDAEALSQRL 1408
Score = 32.3 bits (72), Expect = 0.11 Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 3/127 (2%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC-TEERAELAESRCQETDEQIRLMD 123 +KE Q K + EE +RK++++ + I+ L+ TE AE E R + ++ L + Sbjct: 864 VKEKQTKVEGEL-EEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQEL-E 921 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 + L L E+ ++ I + E K + +++ E + + E KL+ E K+K Sbjct: 922 EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIK 981 Query: 184 CNKEENL 190 +EE L Sbjct: 982 KMEEEIL 988
Score = 31.6 bits (70), Expect = 0.19 Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 7/100 (7%) Query: 80 ADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQK 139 A+ K +++ +++++E + +L E R E Q+ ++ K L+ K Sbjct: 976 AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVM 1035 Query: 140 EDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 EE +K KE +TR E E+ KL+ T DL+ Sbjct: 1036 ISDLEERLK------KEEKTRQEL-EKAKRKLDGETTDLQ 1068
Score = 31.6 bits (70), Expect = 0.19 Identities = 23/115 (20%), Positives = 49/115 (42%) Query: 68 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 127 +Q+ + + D + +V K +EG+LE E + + EQ++ + Sbjct: 845 LQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFA 904 Query: 128 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 + + + K+ EE + L +++E E R + + K++ DLE +L Sbjct: 905 EAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Score = 31.2 bits (69), Expect = 0.25 Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 14/127 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVI-----IEGDLECTEERAELAESRCQETDEQ 118 + K + +K+ + + EA+ + E R L + +E DL+ E + E A E +Q Sbjct: 1589 EKKRLLIKQVREL--EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646 Query: 119 IRLMDQNLKCLS-DAEEKYSQKEDIY------EEEIKILTDKLKEAETRAEFTERLVAKL 171 +R + +K + EE + +++I+ E+++K L ++ + + +ER Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706 Query: 172 EKTTDDL 178 E+ D+L Sbjct: 1707 EQERDEL 1713
Score = 30.8 bits (68), Expect = 0.33 Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 28/156 (17%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD-- 131 +H +E D +E+ G +E+ L E+R + +E++ N++ L+D Sbjct: 1704 RHAEQERDELADEITNSA---SGKSALLDEKRRL-EARIAQLEEELEEEQSNMELLNDRF 1759 Query: 132 ---------------AEEKYSQKEDIYEEEI----KILTDKLKEAE--TRAEFTERLVAK 170 AE +QK D +++ K L KL+E E +++F + ++ Sbjct: 1760 RKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKF-KATISA 1818 Query: 171 LEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEM 206 LE LE +L+ +E +++ +T L E+ Sbjct: 1819 LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEI 1854
Score = 30.8 bits (68), Expect = 0.33 Identities = 29/93 (31%), Positives = 48/93 (51%), Gaps = 9/93 (9%) Query: 109 ESRCQETDEQI-RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK-EAETRAEFTE- 165 E Q DE++ ++ ++ K + EE + + + EE+ IL ++L+ E E AE E Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK-NILAEQLQAETELFAEAEEM 909 Query: 166 --RLVAK---LEKTTDDLEYKLKCNKEENLCTQ 193 RL AK LE+ DLE +++ +E N Q Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQ 942
Score = 28.1 bits (61), Expect = 2.1 Identities = 31/150 (20%), Positives = 65/150 (43%), Gaps = 8/150 (5%) Query: 40 AQERLTTAL---QKLXXXXXXXXXXXRDMKEIQ--LKEAKHIAEEADRKYEEVPRKLVII 94 A+E+ T AL + L R K+++ +++ ++ + E+ + + Sbjct: 1478 AREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRAL 1537 Query: 95 EGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIK-ILTDK 153 E +E + E E Q T++ ++ N++ + E+ Q D EE K +L + Sbjct: 1538 EQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ 1597 Query: 154 LK--EAETRAEFTERLVAKLEKTTDDLEYK 181 ++ EAE E +R +A K +++ K Sbjct: 1598 VRELEAELEDERKQRALAVASKKKMEIDLK 1627
Score = 26.9 bits (58), Expect = 4.7 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 8/123 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLV-IIEGDLECTEERAELAESRCQETDEQIRL 121 R E Q KE K +E + + + + +E + EE+ E ++ +R Sbjct: 1787 RQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRR 1846 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEI-------KILTDKLKEAETRAEFTERLVAKLEKT 174 ++ LK + E + D Y+E++ K L +L+EAE A KL++ Sbjct: 1847 TEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRE 1906 Query: 175 TDD 177 DD Sbjct: 1907 LDD 1909
Score = 26.9 bits (58), Expect = 4.7 Identities = 41/204 (20%), Positives = 73/204 (35%), Gaps = 44/204 (21%) Query: 17 LQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHI 76 LQQ+ DD DH Q ++ + L+K + + +E Sbjct: 1425 LQQELDDLTVDL---------DH-QRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRA 1474 Query: 77 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 EA K + +E LE EE QN + +D E+ Sbjct: 1475 EAEAREKETKALSLARALEEALEAKEE-----------------FERQNKQLRADMEDLM 1517 Query: 137 SQKEDI-------------YEEEIKILTDKLKEAETRAEFTE----RLVAKLEKTTDDLE 179 S K+D+ E++++ + +L+E E + TE RL ++ E Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFE 1577 Query: 180 YKLKCNKEENLCTQRMLYQTLLDL 203 L+ E+N +R+L + + +L Sbjct: 1578 RDLQTRDEQNEEKKRLLIKQVREL 1601
Score = 26.6 bits (57), Expect = 6.2 Identities = 25/124 (20%), Positives = 52/124 (41%), Gaps = 11/124 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 EI LK+ + E A++ +EV ++L ++ ++ + E A + E Q + ++ L Sbjct: 1623 EIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL 1682 Query: 127 KC-----------LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 175 K L+ +E E +E +T+ + RL A++ + Sbjct: 1683 KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE 1742 Query: 176 DDLE 179 ++LE Sbjct: 1743 EELE 1746
>gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE) Length = 1940 Score = 39.7 bits (91), Expect = 7e-04 Identities = 36/149 (24%), Positives = 67/149 (44%), Gaps = 35/149 (23%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAELAESRCQE 114 QLK+ + ++A R E++ +L I+E LE TE +LAE + Sbjct: 1650 QLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 1709 Query: 115 TDEQIRLMD-QNLKCL--------------SDAEEKYSQKEDIYEEEIKILTD------K 153 ++E+++L+ QN + S+ E+ + E+ K +TD + Sbjct: 1710 SNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEE 1769 Query: 154 LKEAETRAEFTERLVAKLEKTTDDLEYKL 182 LK+ + + ER+ LE+T DL+++L Sbjct: 1770 LKKEQDTSAHLERMKKNLEQTVKDLQHRL 1798
Score = 37.4 bits (85), Expect = 0.004 Identities = 29/137 (21%), Positives = 62/137 (45%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 917 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 974 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + L L + K ++++ +E + D L+ E + + +KLE+ +D Sbjct: 975 KVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVED 1034 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1035 LESSLEQEKKLRVDLER 1051
Score = 36.2 bits (82), Expect = 0.008 Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 1/139 (0%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+++ + E+ + ++ R +EGDL+ +E E+ Q+ DE+++ D Sbjct: 1029 EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEY 1088 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 L E ++++IK L +++E E E AK EK D +L+ Sbjct: 1089 CQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELE-EL 1147 Query: 187 EENLCTQRMLYQTLLDLNE 205 E L + T ++LN+ Sbjct: 1148 SERLEEAGGVTSTQIELNK 1166
Score = 34.7 bits (78), Expect = 0.023 Identities = 21/71 (29%), Positives = 37/71 (52%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D ++++K K AEEAD + K + +LE EERA++AES+ + + R Sbjct: 1870 DKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFT 1929 Query: 124 QNLKCLSDAEE 134 + + ++EE Sbjct: 1930 SSRMVVHESEE 1940
Score = 31.2 bits (69), Expect = 0.25 Identities = 40/193 (20%), Positives = 84/193 (43%), Gaps = 10/193 (5%) Query: 5 ATMEEVKCKIQVLQQQA-DDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXR 63 AT+E+ + ++ +Q+ D H +++L T L +L R Sbjct: 1691 ATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDAR 1750 Query: 64 DMKEIQLK---EAKHIAEEADRKYEEVPRKLVIIEGDLECT----EERAELAESRCQETD 116 + +E K +A +AEE +K ++ L ++ +LE T + R + AE + Sbjct: 1751 NAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1809 Query: 117 E-QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 175 + QI+ ++ ++ L E +K + ++ ++KE ++E + V +L+ Sbjct: 1810 KKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLV 1869 Query: 176 DDLEYKLKCNKEE 188 D L+ K+K K + Sbjct: 1870 DKLQVKVKSYKRQ 1882
Score = 30.0 bits (66), Expect = 0.56 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 14/134 (10%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLE----CTEERAELAESRCQETDE 117 MKE + ++ K +++ K +E+ KLV + + DL+ E AE RC + + Sbjct: 853 MKE-EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIK 911 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLEKT 174 ++ +K + E+ +E+I E + + L D+ E + + E +AK+EK Sbjct: 912 AKFQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 968 Query: 175 TDDLEYKLKCNKEE 188 E K+K EE Sbjct: 969 KHATENKVKNLTEE 982
Score = 27.3 bits (59), Expect = 3.6 Identities = 24/119 (20%), Positives = 50/119 (42%), Gaps = 5/119 (4%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D+ EI+++ A+R+ E + L ++G L+ T+ + A ++ EQ+ +++ Sbjct: 1622 DLNEIEIQ-----LSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 1676 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 + L E+ + E K+ +L ++ R + L T LE L Sbjct: 1677 RRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
Score = 26.2 bits (56), Expect = 8.1 Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 10/96 (10%) Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKED 141 RKYE ++L + E+R + R Q+ +++++ +K E+ ++ + Sbjct: 1842 RKYERRVKELTY-----QSEEDRKNVL--RLQDLVDKLQV---KVKSYKRQAEEADEQAN 1891 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 + + + +L+EAE RA+ E V KL T D Sbjct: 1892 AHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRD 1927
>gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) Length = 2871 Score = 38.9 bits (89), Expect = 0.001 Identities = 32/147 (21%), Positives = 68/147 (46%), Gaps = 10/147 (6%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAEL---------AESRCQETDEQI 119 L +A ++ +++ E + + + D +C E E A L A S ET ++ Sbjct: 1469 LDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKL 1528 Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 ++ +Q L L E+ SQ+ + +++I + LKE + + + E + +L++T + Sbjct: 1529 KVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDS 1588 Query: 180 YKLKCNKEENLCTQRMLYQTLLDLNEM 206 K K +EE +R L + + + + Sbjct: 1589 CKRKKLEEELEGMRRSLKEQAIKITNL 1615
Score = 32.0 bits (71), Expect = 0.15 Identities = 32/130 (24%), Positives = 57/130 (43%), Gaps = 20/130 (15%) Query: 71 KEAKHIAEEADR---KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 127 +E + ++EE R + L +E D++ + R Q+ + ++R + Q Sbjct: 1400 RENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQ--- 1456 Query: 128 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 EE K+ + ++ K + DK KE E RL ++K T+D KC ++ Sbjct: 1457 --MRTEESVRYKQSL-DDAAKTIQDKNKEIE-------RLKQLIDKETNDR----KCLED 1502 Query: 188 ENLCTQRMLY 197 EN QR+ Y Sbjct: 1503 ENARLQRVQY 1512
>gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) Length = 1116 Score = 38.9 bits (89), Expect = 0.001 Identities = 27/136 (19%), Positives = 64/136 (47%), Gaps = 4/136 (2%) Query: 71 KEAKHIAEEADRKYEEVP--RKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 KE + EE R++E P K ++ +E + + E ++ +E+I+++ N Sbjct: 355 KENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGAL 414 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 ++ E+ ++ ++Y K + +K+++ + E +L+K L+ ++ K+E Sbjct: 415 STEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQE 474 Query: 189 --NLCTQRMLYQTLLD 202 T+ + QT L+ Sbjct: 475 LSRKDTELLALQTKLE 490
Score = 30.0 bits (66), Expect = 0.56 Identities = 25/138 (18%), Positives = 62/138 (44%), Gaps = 11/138 (7%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK-- 127 LKE ++ + D+K E+ R++ + + + ++ + + + E+ R + NL Sbjct: 765 LKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDS 824 Query: 128 ------CLSDAEEKYSQKEDIYEEEIKILTDK---LKEAETRAEFTERLVAKLEKTTDDL 178 L +++ + E+ E ++I ++ L + E+ E+ V +L + + Sbjct: 825 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 884 Query: 179 EYKLKCNKEENLCTQRML 196 + +L+ K + TQ+ L Sbjct: 885 KQELESMKAKLSSTQQSL 902
Score = 28.5 bits (62), Expect = 1.6 Identities = 31/141 (21%), Positives = 56/141 (39%), Gaps = 6/141 (4%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE---QIRL- 121 KE L + K A + +L +E LE +E ES+ ++ E + R Sbjct: 671 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS 730 Query: 122 --MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 M ++ L +Y + + E+ L + LKE E ++ +A+LE+ D Sbjct: 731 PEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQN 790 Query: 180 YKLKCNKEENLCTQRMLYQTL 200 K+ K + ++ Q L Sbjct: 791 KKVANLKHKEQVEKKKSAQML 811
Score = 28.1 bits (61), Expect = 2.1 Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 14/122 (11%) Query: 45 TTALQKLXXXXXXXXXXXRDMKE-IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE 103 T +Q + D+K+ + +KE K +K E + +L E + +E Sbjct: 542 TKQIQDMAEEKGTQAGEIHDLKDMLDVKERK--VNVLQKKIENLQEQLRDKEKQMSSLKE 599 Query: 104 RAELAESRCQETDEQIRLMD----------QNLKCLSDAEEKYSQKE-DIYEEEIKILTD 152 R + ++ TD + ++ + LK D +E+ Q+E D Y++++K L + Sbjct: 600 RVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKE 659 Query: 153 KL 154 K+ Sbjct: 660 KV 661
>gi|48428694|sp|Q9Y228|TJAM_HUMAN TRAF3-interacting JNK-activating modulator Length = 531 Score = 38.5 bits (88), Expect = 0.002 Identities = 27/127 (21%), Positives = 61/127 (48%), Gaps = 9/127 (7%) Query: 68 IQLKEAKHIAEE-ADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 +++++ K+ E+ A ++V + + E L+ T+ LAE +C+E Q + ++ Sbjct: 250 LEMEDQKNSYEQKAKESLQKVLEEKMNAEQQLQSTQRSLALAEQKCEEWRSQYEALKEDW 309 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC-N 185 + L + E ++ +L KL+ A++R + + LE L+ K++C Sbjct: 310 RTLGTQHRE-------LESQLHVLQSKLQGADSRDLQMNQALRFLENEHQQLQAKIECLQ 362 Query: 186 KEENLCT 192 + +LC+ Sbjct: 363 GDRDLCS 369
>gi|729094|sp|P39880|CUTL1_HUMAN CCAAT displacement protein (CDP) (Cut-like 1) Length = 1505 Score = 38.1 bits (87), Expect = 0.002 Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 25/163 (15%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD 97 +H + L TAL+K ++ +++ K + +AD ++ +I D Sbjct: 194 EHKVQSLQTALEKTRT----------ELFDLKTKYDEETTAKAD--------EIEMIMTD 235 Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 LE +RAE+A+ + EQ+ + +L+ S QK E+ I++LT E Sbjct: 236 LERANQRAEVAQREAETLREQLSSANHSLQLASQI-----QKAPDVEQAIEVLTRSSLEV 290 Query: 158 ETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTL 200 E A+ ER +A+L + L+ L +E + L Q L Sbjct: 291 ELAAK--EREIAQLVEDVQRLQASLTKLRENSASQISQLEQQL 331
Score = 32.0 bits (71), Expect = 0.15 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 10/125 (8%) Query: 63 RDMKEIQLKEAKHIAEEADRK----YEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ 118 R+ ++ +A+ IA E ++K + E RKL + E AE Q E+ Sbjct: 147 REYEQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEK 206 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 R L D + KY ++ +EI+++ L+ A RAE +R L + Sbjct: 207 TRTE------LFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSA 260 Query: 179 EYKLK 183 + L+ Sbjct: 261 NHSLQ 265
>gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmuscle type A (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 38.1 bits (87), Expect = 0.002 Identities = 37/123 (30%), Positives = 60/123 (48%), Gaps = 8/123 (6%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLE--C--TEERAELAESRCQETDEQIRL 121 +++QL+E E + EE+ +L + +LE C E R E E RCQ + + Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940 Query: 122 MDQNLKCLSD-AEEKYSQKEDIYEEEIKILTD-KLKEAETRAEFTERLVAKLEKTTDDLE 179 M QN++ L + EE+ S ++ + E K+ T+ KLK+ E E KL K LE Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE--KVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998 Query: 180 YKL 182 ++ Sbjct: 999 DRI 1001
Score = 30.4 bits (67), Expect = 0.43 Identities = 27/148 (18%), Positives = 66/148 (44%), Gaps = 15/148 (10%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQ---------LKEAKHIAEEADRKYEEVPRKL 91 +E L AL ++ + ++E++ L+ + +A+++ ++ +L Sbjct: 1082 EEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEEL 1141 Query: 92 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILT 151 ++ +LE T + + + ++++ ++ + L+ EE + + I E K + Sbjct: 1142 EALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE-----EEAKTHEAQIQEMRQKH-S 1195 Query: 152 DKLKEAETRAEFTERLVAKLEKTTDDLE 179 ++E + E T+R+ A LEK LE Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Score = 29.6 bits (65), Expect = 0.73 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 8/123 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYE-EVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 R E Q KE K +E + + + + +E + EE+ + Q +Q+R Sbjct: 1780 RQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRR 1839 Query: 122 MDQNLKCL---SDAE----EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 ++ LK + D E E+Y + D +K L +L+EAE A+ KL++ Sbjct: 1840 TEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899 Query: 175 TDD 177 +D Sbjct: 1900 LED 1902
Score = 26.2 bits (56), Expect = 8.1 Identities = 21/127 (16%), Positives = 55/127 (43%), Gaps = 14/127 (11%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E +++E + + + +++ + + +E LE E + + T+ +++ +++ Sbjct: 921 EARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQ 980 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL--------------VAKLE 172 L D K ++++ + E+ I T L E E +++ +L + + E Sbjct: 981 IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040 Query: 173 KTTDDLE 179 K +LE Sbjct: 1041 KQRQELE 1047
>gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen) Length = 2115 Score = 37.7 bits (86), Expect = 0.003 Identities = 28/128 (21%), Positives = 62/128 (48%), Gaps = 10/128 (7%) Query: 79 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQ 138 +A R+ E+ RK+ ++ +E + A+++ E + Q+R Q + +E+ +Q Sbjct: 640 QAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK----ATEKERVAQ 695 Query: 139 KEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 198 ++D +E+++ L + LK + E +R + D LE + +C E T+ ++ Q Sbjct: 696 EKDQLQEQLQALKESLKVTKGSLEEEKR------RAADALEEQQRCISELKAETRSLVEQ 749 Query: 199 TLLDLNEM 206 + E+ Sbjct: 750 HKRERKEL 757
Score = 32.3 bits (72), Expect = 0.11 Identities = 40/168 (23%), Positives = 67/168 (39%), Gaps = 24/168 (14%) Query: 63 RDMKEIQLKEAKHIAEEADRKY----EEVPRKLVIIEGDLECTEERAELAESR------- 111 RD E++L E + + E D + + + R ++ E E EL E R Sbjct: 230 RDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289 Query: 112 ---------CQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE-AETRA 161 CQ+ + MD+ + LS+ S K + ++ L D L E E + Sbjct: 290 MRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHS 349 Query: 162 EFTERLV---AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNEM 206 + T+ + A+LEK KC +E+N Q L Q L+++ Sbjct: 350 KATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 397
Score = 28.9 bits (63), Expect = 1.2 Identities = 24/127 (18%), Positives = 64/127 (50%), Gaps = 7/127 (5%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q+++ + E ++ EE+ +KL + + +++ + +++ E+ ++ + + Sbjct: 1536 QVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQ--- 1592 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 L++ + + SQKE E K+ ++++A+T + ++ +L++ LE K NKE Sbjct: 1593 LNELQAQLSQKEQA-AEHYKL---QMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1648 Query: 189 NLCTQRM 195 +R+ Sbjct: 1649 RAEAERL 1655
Score = 26.6 bits (57), Expect = 6.2 Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 1/58 (1%) Query: 131 DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 +AE K S + EEE+ IL ++ E E ++ +RLV + + LE +L+ + E Sbjct: 1219 EAERKNSLISSL-EEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE 1275
>gi|1730008|sp|P53804|TTC3_HUMAN Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D) Length = 2025 Score = 37.7 bits (86), Expect = 0.003 Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 1/111 (0%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 129 L+E + + E+ R EE ++ L+ E + + +E E+++ + + +K + Sbjct: 1521 LEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKKWQQEKKEIQERLKSLKKKIKKV 1580 Query: 130 SDAEEKYSQKEDIYEEEIKI-LTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 S+A E Y+QK D E+E ++ L L+ + T ++ ++K +D E Sbjct: 1581 SNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMKIEEYIKKGKEDYE 1631
Score = 30.0 bits (66), Expect = 0.56 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Query: 144 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDL 203 E+E ++L D+L+E E E++ K + T DLE KLK + EEN ++ L L DL Sbjct: 1496 EKEHQVLQDQLQEVY---ENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDL 1552
>gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skeletal muscle, adult 1 (Myosin heavy chain IIx/d) (MyHC-IIx/d) Length = 1939 Score = 37.7 bits (86), Expect = 0.003 Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 7/120 (5%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D E L++ K I + +R RKL EGDL+ +E A E+ Q+ DE+++ + Sbjct: 1036 DDLEGSLEQEKKIRMDLER----AKRKL---EGDLKLAQESAMDIENDKQQLDEKLKKKE 1088 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 + L E +++IK L +++E E E AK EK DL +L+ Sbjct: 1089 FEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Score = 37.4 bits (85), Expect = 0.004 Identities = 37/172 (21%), Positives = 68/172 (39%), Gaps = 56/172 (32%) Query: 67 EIQLKEAKHIAEEADRKY---------------------EEVPRKLVIIE---------- 95 EIQL A +A EA R Y E++ +L ++E Sbjct: 1630 EIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEI 1689 Query: 96 ----GDLECTEERAELAESRCQETDEQIRLM--------DQNLKCLSDAEEKYSQKEDIY 143 LE TE ++AE + E+++L+ + K +D + + EDI Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749 Query: 144 EE-------------EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 +E + ++ ++LK+ + + ER+ LE+T DL+++L Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Score = 36.6 bits (83), Expect = 0.006 Identities = 29/137 (21%), Positives = 61/137 (44%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 977 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1037 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1038 LEGSLEQEKKIRMDLER 1054
Score = 31.2 bits (69), Expect = 0.25 Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D + ++K K AEEA+ + K I+ +LE EERA++AES+ + +++ + Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKL--RVKSRE 1930 Query: 124 QNLKCLSD 131 + K +S+ Sbjct: 1931 VHTKIISE 1938
Score = 30.4 bits (67), Expect = 0.43 Identities = 32/142 (22%), Positives = 65/142 (45%), Gaps = 24/142 (16%) Query: 65 MKEIQ--LKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQE 114 +K++Q L EA+ +A + +K +++ ++ +EG++E ++R A E + +E Sbjct: 1794 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKE 1853 Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETR 160 Q +N+ L D +K K Y+ + + + +L+EAE R Sbjct: 1854 LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEER 1913 Query: 161 AEFTERLVAKLEKTTDDLEYKL 182 A+ E V KL + ++ K+ Sbjct: 1914 ADIAESQVNKLRVKSREVHTKI 1935
Score = 30.0 bits (66), Expect = 0.56 Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 10/121 (8%) Query: 92 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEE------ 145 ++ E +C E AEL S+ E L + K + EE Q E + E Sbjct: 1456 ILAEWKQKCEETHAELEASQ----KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511 Query: 146 EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE 205 EI LT+++ E R E++ ++E+ +L+ L+ + + + + L+LN+ Sbjct: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571 Query: 206 M 206 + Sbjct: 1572 V 1572
Score = 30.0 bits (66), Expect = 0.56 Identities = 28/114 (24%), Positives = 48/114 (42%), Gaps = 8/114 (7%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI----RLMDQNLKCLSDAE 133 EE R+ EE + + L+ + +L + +E E R M + ++ Sbjct: 1317 EELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWR 1376 Query: 134 EKYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 KY Q+ + EE K L +L++AE E A LEKT L+ +++ Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 1430
Score = 30.0 bits (66), Expect = 0.56 Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD--LECTEERAELAESRCQETDEQIRLMD 123 +E + ++ + EEA ++E L D E E+ L + Q+ +++ M Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK-QKLEKEKSEMK 1229 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL-----EKTTDDL 178 + L+ E S+ + E+ + L D+L E +T+ E +RL+ L T+ Sbjct: 1230 MEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG 1289 Query: 179 EYKLKCNKEENLCTQ 193 EY + ++++ L +Q Sbjct: 1290 EYSRQLDEKDTLVSQ 1304
Score = 29.3 bits (64), Expect = 0.95 Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 16/136 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQET 115 +MKE + ++ K + + K +E+ K+V + + DL+ + +AE AE RC + Sbjct: 855 NMKE-EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADSLADAEERCDQL 912 Query: 116 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLE 172 + ++ +K + E+ +E+I E + + L D+ E + + E +AK+E Sbjct: 913 IKTKIQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969 Query: 173 KTTDDLEYKLKCNKEE 188 K E K+K EE Sbjct: 970 KEKHATENKVKNLTEE 985
Score = 26.6 bits (57), Expect = 6.2 Identities = 41/196 (20%), Positives = 88/196 (44%), Gaps = 16/196 (8%) Query: 5 ATMEEVKCKIQVLQQQA-DDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXR 63 AT+E+ + ++ +Q+ D + +++L T + ++ R Sbjct: 1694 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEAR 1753 Query: 64 DMKEIQLK---EAKHIAEEADRKYEEVPRKLVIIEGDLECT----EERAELAESRCQETD 116 + +E K +A +AEE +K ++ L ++ +LE T + R + AE + Sbjct: 1754 NAEEKAKKAITDAAMMAEEL-KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1812 Query: 117 E-QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTD---KLKEAETRAEFTERLVAKLE 172 + QI+ ++ ++ L + E + QK ++ E +K L K+KE + E + + +L+ Sbjct: 1813 KKQIQKLEARVREL-EGEVESEQKRNV--EAVKGLRKHERKVKELTYQTEEDRKNILRLQ 1869 Query: 173 KTTDDLEYKLKCNKEE 188 D L+ K+K K + Sbjct: 1870 DLVDKLQAKVKSYKRQ 1885
>gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8 (230 kDa bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) Length = 3214 Score = 37.7 bits (86), Expect = 0.003 Identities = 28/126 (22%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q+ E +A++ E+ +L ++ + +EE+A L + + ET+ +R + L+ Sbjct: 1932 QVDELTAANRKAEQDMRELTYELNALQLEKTSSEEKARLLKDKLDETNNTLRCLKLELER 1991 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY-KLKCNKE 187 AE+ YSQ+ ++ T K +EA A +++ + + L + K K +E Sbjct: 1992 KDQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQRE 2051 Query: 188 ENLCTQ 193 + T+ Sbjct: 2052 VDRITR 2057
Score = 33.1 bits (74), Expect = 0.066 Identities = 33/167 (19%), Positives = 75/167 (44%), Gaps = 16/167 (9%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMKEI--QLKEAKHIAEEADRKYEEVPR-----K 90 DH +E+ + ++L ++ + +L+++ AE +K EE+ R K Sbjct: 2093 DHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNEELEKSNECAEMLKQKVEELTRQNNETK 2152 Query: 91 LVI--IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIK 148 L++ I+ + E + + RC+ Q L+ ++ K ++ E ++ +IK Sbjct: 2153 LMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIK 2212 Query: 149 ILTDKLKEAETR-AEFTER------LVAKLEKTTDDLEYKLKCNKEE 188 L + L +++ +EF ++ ++ +K +L +L +KEE Sbjct: 2213 CLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEE 2259
Score = 32.0 bits (71), Expect = 0.15 Identities = 17/97 (17%), Positives = 45/97 (46%), Gaps = 7/97 (7%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRC-------QETDEQIRL 121 QL+ + + ++ RK+ +E DL ++ + +C Q T +++R Sbjct: 2189 QLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRN 2248 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 ++ L + + + QK + + +++ L ++LK+ + Sbjct: 2249 LNAELNASKEEKRRGEQKVQLQQAQVQELNNRLKKVQ 2285
Score = 28.1 bits (61), Expect = 2.1 Identities = 21/88 (23%), Positives = 38/88 (43%), Gaps = 14/88 (15%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDL--------------ECTEERAELAESRCQETDEQI 119 K AEE +K E++ VI E D+ +E A+L E+ +E + Q+ Sbjct: 2313 KQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCETNIKELERQL 2372 Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEI 147 + + ++ E + QK E+E+ Sbjct: 2373 QQYREQMQQGQHMEANHYQKCQKLEDEL 2400
>gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skeletal muscle, fetal (Myosin heavy chain IIb) (MyHC-IIb) Length = 1939 Score = 37.4 bits (85), Expect = 0.004 Identities = 30/134 (22%), Positives = 61/134 (45%), Gaps = 13/134 (9%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 977 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 978 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDD 1037 Query: 178 LEYKLKCNKEENLC 191 LE L+ +E+ LC Sbjct: 1038 LEGSLE--QEKKLC 1049
Score = 35.0 bits (79), Expect = 0.017 Identities = 32/157 (20%), Positives = 70/157 (44%), Gaps = 37/157 (23%) Query: 63 RDMKEIQ--LKEAKHIAEEADRKYEEVPRKLVIIE--------------GDLECTEERAE 106 R+++ Q LK+ + ++A R +++ +L ++E LE TE + Sbjct: 1645 RNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRK 1704 Query: 107 LAESRCQETDEQIRLMD-QNLKCLS-------DAEEKYSQKEDIYEE------------- 145 +AE + E+++L+ QN ++ D + + EDI +E Sbjct: 1705 MAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAIT 1764 Query: 146 EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 + ++ ++LK+ + + ER+ +E+T DL+ +L Sbjct: 1765 DAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1801
Score = 34.7 bits (78), Expect = 0.023 Identities = 27/117 (23%), Positives = 53/117 (45%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ +E+++ + + Sbjct: 1032 EQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEM 1091 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L E +++IK L +++E E E AK EK DL +L+ Sbjct: 1092 SNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Score = 30.4 bits (67), Expect = 0.43 Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 8/114 (7%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL-KCLSDAEE-- 134 EE R+ EE + + L+ +L + +E E + + + K S+ + Sbjct: 1317 EELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWR 1376 Query: 135 -KYS----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 KY Q+ + EE K L +L++AE E A LEKT L+ +++ Sbjct: 1377 TKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
Score = 30.0 bits (66), Expect = 0.56 Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D + ++K K AEEA+ + K ++ +LE EERA++AES+ + +++ + Sbjct: 1873 DKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEERADIAESQVNKL--RVKSRE 1930 Query: 124 QNLKCLSD 131 + K +S+ Sbjct: 1931 VHTKVISE 1938
Score = 29.3 bits (64), Expect = 0.95 Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 24/142 (16%) Query: 65 MKEIQLK--EAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQE 114 +K++QL+ EA+ +A + +K +++ ++ +E ++E ++ A E R +E Sbjct: 1794 VKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKE 1853 Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETR 160 Q +N+ L D +K K Y+ + + L +L+EAE R Sbjct: 1854 LTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAEER 1913 Query: 161 AEFTERLVAKLEKTTDDLEYKL 182 A+ E V KL + ++ K+ Sbjct: 1914 ADIAESQVNKLRVKSREVHTKV 1935
Score = 29.3 bits (64), Expect = 0.95 Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 16/136 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQET 115 +MKE + ++ K + + K +E+ K+V + + DL+ + +AE AE RC + Sbjct: 855 NMKE-EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQL-QVQAEADALADAEERCDQL 912 Query: 116 DEQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLE 172 + ++ +K + E+ +E+I E + + L D+ E + + E +AK+E Sbjct: 913 IKTKIQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 969 Query: 173 KTTDDLEYKLKCNKEE 188 K E K+K EE Sbjct: 970 KEKHATENKVKNLTEE 985
Score = 26.9 bits (58), Expect = 4.7 Identities = 17/86 (19%), Positives = 44/86 (51%), Gaps = 5/86 (5%) Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE 172 Q+ +++ + + L+ E S+ + +E+ + L D+L E +T+ E +RL+ +L Sbjct: 1219 QKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELS 1278 Query: 173 KT-----TDDLEYKLKCNKEENLCTQ 193 T+ E+ + ++++ + +Q Sbjct: 1279 AQKARLHTESGEFSRQLDEKDAMVSQ 1304
Score = 26.6 bits (57), Expect = 6.2 Identities = 23/147 (15%), Positives = 59/147 (40%), Gaps = 1/147 (0%) Query: 42 ERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECT 101 + LT + L + ++E + + E D K + + +E ++ Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED-KVNTLTKAKTKLEQQVDDL 1038 Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 E E + C + + R ++ +LK ++ + E++K ++ + + Sbjct: 1039 EGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKI 1098 Query: 162 EFTERLVAKLEKTTDDLEYKLKCNKEE 188 E + L +L+K +L+ +++ +EE Sbjct: 1099 EDEQALAMQLQKKIKELQARIEELEEE 1125
>gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory factor (TMF) Length = 1093 Score = 37.0 bits (84), Expect = 0.005 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 13/124 (10%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD---------EQIRLMDQNLKC 128 E A+ K EEV LVI + E E C++ D E ++D+ + Sbjct: 371 ESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQ 430 Query: 129 LSDAE---EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 AE E S+KED+ + ++ L +KL++ E + + A LE+ D+L+ ++ Sbjct: 431 CEPAESQPEALSEKEDVC-KTVEFLNEKLEKREAQLLSLSKEKALLEEAFDNLKDEMFRV 489 Query: 186 KEEN 189 KEE+ Sbjct: 490 KEES 493
Score = 32.7 bits (73), Expect = 0.086 Identities = 35/135 (25%), Positives = 66/135 (48%), Gaps = 7/135 (5%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 KE+ + A++++ + + R++ E +L E+A+ E+R Q+ I++ D Sbjct: 665 KELTDLHKANAAKDSEAQEAALSREMKAKE-ELSAALEKAQ-EEARQQQETLAIQVGDLR 722 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 L L E+ ++KED EI L +L+EAE R + L + TT L +++ N Sbjct: 723 L-ALQRTEQAAARKEDYLRHEIGELQQRLQEAENR---NQELSQSVSSTTRPLLRQIE-N 777 Query: 186 KEENLCTQRMLYQTL 200 + L +Q ++ L Sbjct: 778 LQATLGSQTSSWEKL 792
Score = 30.4 bits (67), Expect = 0.43 Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 7/74 (9%) Query: 114 ETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 ET + ++ D+ ++ L + EK S+++ IK L K KE E +VAKL K Sbjct: 543 ETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKE-------NENMVAKLNK 595 Query: 174 TTDDLEYKLKCNKE 187 +LE +L+ K+ Sbjct: 596 KVKELEEELQHLKQ 609
>gi|462594|sp|P35240|MERL_HUMAN Merlin (Moesin-ezrin-radixin-like protein) (Schwannomin) (Schwannomerlin) (Neurofibromin 2) Length = 595 Score = 37.0 bits (84), Expect = 0.005 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 21/120 (17%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 + M+ +L K + EEA+R +E+ R+L+ ++ E A +A ++E L+ Sbjct: 332 KQMERQRLAREKQMREEAERTRDELERRLLQMK-------EEATMANEALMRSEETADLL 384 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 ++K I EEE K+L K EAE + + + E+ +E K+ Sbjct: 385 --------------AEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKV 430
>gi|1169868|sp|P32456|GBP2_HUMAN Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (HuGBP-2) Length = 591 Score = 37.0 bits (84), Expect = 0.005 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Query: 72 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 131 +AK + ++ E+V L+ + L E+ E+ + + + +++++ K Sbjct: 454 QAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQK---K 510 Query: 132 AEEKYSQKEDIYEEEIKILTDKLK--EAETRAEFTERLVAKLEK 173 EE QKE Y+E +K LT+K++ A+ AE + L KL++ Sbjct: 511 NEEMMEQKEKSYQEHVKQLTEKMERDRAQLMAEQEKTLALKLQE 554
>gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 2) (PTPRF-interacting protein alpha 2) Length = 1257 Score = 37.0 bits (84), Expect = 0.005 Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 7/128 (5%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q+ E + + E+ + + ++ +L + + E+ AE A +T+E N K Sbjct: 269 QIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTEEM------NTKY 322 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 D E +QKED+ EE I L + A+ + + KLE + E L+ +E+ Sbjct: 323 QRDIREAMAQKEDM-EERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEK 381 Query: 189 NLCTQRML 196 N Q L Sbjct: 382 NRQLQERL 389
Score = 35.4 bits (80), Expect = 0.013 Identities = 40/161 (24%), Positives = 71/161 (44%), Gaps = 23/161 (14%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMK---EIQLKEAKHIAEEADRKYEEVPRKLVIIEGD 97 +ER+TT L+K DM E +L + I + + K ++ +L + E Sbjct: 337 EERITT-LEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEEK 395 Query: 98 LECTEERAE-------------LAESRCQET----DEQIRLMDQNLKCLSDAEEKYSQKE 140 L+ T +AE A ++ +ET +E++R ++ L+ + ++ Q+E Sbjct: 396 LQQTMRKAETLPEVEAELAQRIAALTKAEETHGNIEERMRHLEGQLEEKNQELQRARQRE 455 Query: 141 DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 + EE K L+D + T E ERL L++ LE K Sbjct: 456 KMNEEHNKRLSDTVDRLLT--ESNERLQLHLKERMAALEEK 494
>gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A) (Myosin containing PDZ domain) Length = 2054 Score = 36.6 bits (83), Expect = 0.006 Identities = 47/219 (21%), Positives = 86/219 (39%), Gaps = 43/219 (19%) Query: 2 AGIATMEEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXX 61 A + + ++ +I+ L Q DD +E+L+ ++ Sbjct: 1701 AAVKARKAMEVEIEDLHLQIDDIAKAKTAL---------EEQLSRLQREKNEIQNRLEED 1751 Query: 62 XRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 DM E+ +K+ K +A R ++ +E E +E+ EL E + Q Q+ Sbjct: 1752 QEDMNEL-MKKHKAAVAQASRDLAQINDLQAQLE---EANKEKQELQE-KLQALQSQVEF 1806 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEF-----------TERLVAK 170 ++Q++ K + +E KI +E ETR EF RL Sbjct: 1807 LEQSMV----------DKSLVSRQEAKI-----RELETRLEFERTQVKRLESLASRLKEN 1851 Query: 171 LEKTTDDLEYKLKC---NKEENLCTQRMLYQTLLDLNEM 206 +EK T++ + ++ KE+N QR L T ++ E+ Sbjct: 1852 MEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGEL 1890
Score = 35.0 bits (79), Expect = 0.017 Identities = 41/168 (24%), Positives = 78/168 (46%), Gaps = 31/168 (18%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E +L + + +EE+ R +++ +K + +L+ T+ E + R E +++ R D L Sbjct: 1408 ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSEL 1467 Query: 127 -KCLSDAEEKYSQKEDIYEEEIKILTD------KLKEAETR-AEFTERLV---------- 168 + +A+ + Q+E + E+ +L + +L+E + A FT+++V Sbjct: 1468 SQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDIS 1527 Query: 169 ----------AKLEKTTDDLEYKLKCNKE---ENLCTQRMLYQTLLDL 203 AK++K DLE K+K +E E T +ML Q L L Sbjct: 1528 SQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRL 1575
Score = 28.9 bits (63), Expect = 1.2 Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 5/118 (4%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 QL++ K E RK E RK +E DLE E + ++ + ++I +L+ Sbjct: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRI----GDLQA 1934 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 + E + + ED+ ++ + K ++ + + E + ++LE D ++ L NK Sbjct: 1935 AIEDEMESDENEDLI-NSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNK 1991
>gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa) Length = 1941 Score = 36.6 bits (83), Expect = 0.006 Identities = 28/117 (23%), Positives = 53/117 (45%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+ + + E+ + ++ R +EGDL+ +E E+ Q+ DE+++ + + Sbjct: 1034 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEI 1093 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L E +++IK L +++E E E AK EK DL +L+ Sbjct: 1094 SNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Score = 36.6 bits (83), Expect = 0.006 Identities = 29/137 (21%), Positives = 61/137 (44%), Gaps = 11/137 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAEL---------AESRCQETDE 117 E ++KE AE+ + E+ K +E EC+E + ++ E T+ Sbjct: 922 EAKIKEVTERAEDEEEINAELTAKKRKLED--ECSELKKDIDDLELTLAKVEKEKHATEN 979 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 +++ + + + L + K ++++ +E + D L+ E + + KLE+ DD Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039 Query: 178 LEYKLKCNKEENLCTQR 194 LE L+ K+ + +R Sbjct: 1040 LEGSLEQEKKLRMDLER 1056
Score = 36.2 bits (82), Expect = 0.008 Identities = 36/172 (20%), Positives = 67/172 (38%), Gaps = 56/172 (32%) Query: 67 EIQLKEAKHIAEEADRKY---------------------EEVPRKLVIIE---------- 95 EIQL A +A EA R Y E++ +L ++E Sbjct: 1632 EIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEI 1691 Query: 96 ----GDLECTEERAELAESRCQETDEQIRLM--------DQNLKCLSDAEEKYSQKEDIY 143 LE TE ++AE + E+++L+ + K +D + + EDI Sbjct: 1692 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDIL 1751 Query: 144 EE-------------EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 +E + ++ ++LK+ + + ER+ +E+T DL+ +L Sbjct: 1752 QEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803
Score = 33.5 bits (75), Expect = 0.051 Identities = 32/138 (23%), Positives = 63/138 (45%), Gaps = 22/138 (15%) Query: 67 EIQLKEAKHIAEEADRKY-EEVPRKLVIIEGDLECTEERAELA-------ESRCQETDEQ 118 +++L EA+ +A + +K +++ ++ +EG++E ++R A E R +E Q Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQ 1859 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEE--------------IKILTDKLKEAETRAEFT 164 +N+ L D +K K Y+ + + L +L+EAE RA+ Sbjct: 1860 TEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIA 1919 Query: 165 ERLVAKLEKTTDDLEYKL 182 E V KL + ++ K+ Sbjct: 1920 ESQVNKLRVKSREVHTKV 1937
Score = 30.8 bits (68), Expect = 0.33 Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 2/68 (2%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D + ++K K AEEA+ + K ++ +LE EERA++AES+ + +++ + Sbjct: 1875 DKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKL--RVKSRE 1932 Query: 124 QNLKCLSD 131 + K +S+ Sbjct: 1933 VHTKVISE 1940
Score = 28.5 bits (62), Expect = 1.6 Identities = 34/135 (25%), Positives = 65/135 (48%), Gaps = 16/135 (11%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVII---EGDLECTEERAEL-----AESRCQETD 116 MKE + ++ K +++ K +E+ K+V + + DL+ + +AE AE RC + Sbjct: 858 MKE-EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQL-QVQAEAEGLADAEERCDQLI 915 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEE---EIKILTDKLKEAETRAEFTERLVAKLEK 173 + ++ +K + E+ +E+I E + + L D+ E + + E +AK+EK Sbjct: 916 KTKIQLEAKIK---EVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEK 972 Query: 174 TTDDLEYKLKCNKEE 188 E K+K EE Sbjct: 973 EKHATENKVKNLTEE 987
Score = 27.7 bits (60), Expect = 2.8 Identities = 28/122 (22%), Positives = 56/122 (45%), Gaps = 12/122 (9%) Query: 92 VIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA-EEKYSQKEDIYEE----- 145 ++ E +C E AEL S+ ++ R + L + +A EE Q E + E Sbjct: 1458 ILAEWKQKCEETHAELEASQ-----KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQ 1512 Query: 146 -EIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 204 EI LT+++ E R E++ ++E+ +L+ L+ + + + + L+LN Sbjct: 1513 QEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELN 1572 Query: 205 EM 206 ++ Sbjct: 1573 QV 1574
Score = 27.3 bits (59), Expect = 3.6 Identities = 29/135 (21%), Positives = 61/135 (45%), Gaps = 8/135 (5%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD--LECTEERAELAESRCQETDEQIRLMD 123 +E + ++ + EEA ++E L D E E+ L + Q+ +++ M Sbjct: 1173 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK-QKLEKEKSEMK 1231 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL-----EKTTDDL 178 + L+ E S+ + E+ + L D+L E +++ E +RL+ L T+ Sbjct: 1232 MEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291 Query: 179 EYKLKCNKEENLCTQ 193 E+ + +++E L +Q Sbjct: 1292 EFSRQLDEKEALVSQ 1306
>gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR Length = 2349 Score = 36.6 bits (83), Expect = 0.006 Identities = 31/129 (24%), Positives = 67/129 (51%), Gaps = 10/129 (7%) Query: 71 KEAKHIAEEADRKYEEVPRKL----VIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 +E + + ++EE+ +K V++E + EE+ L E Q+ ++R ++ ++ Sbjct: 1246 REKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERL-EQDLQQMQAKVRKLELDI 1304 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 L +A + S+K + + E K+L + +K + R + LV++ +K D EY+ K Sbjct: 1305 LPLQEANAELSEKSGMLQAEKKLLEEDVKRWKAR---NQHLVSQ-QKDPDTEEYR-KLLS 1359 Query: 187 EENLCTQRM 195 E+ + T+R+ Sbjct: 1360 EKEVHTKRI 1368
Score = 33.5 bits (75), Expect = 0.051 Identities = 21/89 (23%), Positives = 47/89 (52%), Gaps = 5/89 (5%) Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 +Q ++M+ + + D +E++ +++ E L + L +AET+++ E V L+KT Sbjct: 1451 QQDKVMETSAQSSGDHQEQHVSVQEMQE-----LKETLNQAETKSKSLESQVENLQKTLS 1505 Query: 177 DLEYKLKCNKEENLCTQRMLYQTLLDLNE 205 + E + + +E+ + Q L + DL + Sbjct: 1506 EKETEARNLQEQTVQLQSELSRLRQDLQD 1534
Score = 33.5 bits (75), Expect = 0.051 Identities = 22/92 (23%), Positives = 48/92 (52%), Gaps = 3/92 (3%) Query: 97 DLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 156 +LE ++R +S+ T E++ ++L E+ SQ+ + E++K L +KLKE Sbjct: 98 ELEIAQDRNIAIQSQFTRTKEELEAEKRDL---IRTNERLSQELEYLTEDVKRLNEKLKE 154 Query: 157 AETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 + T + + +L+ + ++Y+ K ++E Sbjct: 155 SNTTKGELQLKLDELQASDVSVKYREKRLEQE 186
Score = 31.6 bits (70), Expect = 0.19 Identities = 52/225 (23%), Positives = 85/225 (37%), Gaps = 77/225 (34%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC 100 Q + ALQ+ RD +E +AK IA EA KYE R+L++ D+E Sbjct: 1044 QNEVQEALQRASTALSNEQQARRDCQE----QAK-IAVEAQNKYE---RELMLHAADVEA 1095 Query: 101 T-----------------EERAELAES-------------------------RCQETDEQ 118 EE + AES RC++ ++Q Sbjct: 1096 LQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQ 1155 Query: 119 IRLMDQNLKCLSD------------------AEEKYSQKEDIYEEEIKILTDKLKEAETR 160 RL+ ++ LSD +EE SQ++ + E ++ + + + AETR Sbjct: 1156 NRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQIL--EILRFIRREKEIAETR 1213 Query: 161 AEFTE-------RLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 198 E + + V LE+ +LE L +E+ T + + Q Sbjct: 1214 FEVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQ 1258
Score = 30.8 bits (68), Expect = 0.33 Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 22/168 (13%) Query: 39 HAQERLTTALQK-------LXXXXXXXXXXXRDMKEIQLKEAKHIA---------EEADR 82 H+QERL ++ L KE+++ + ++IA EE + Sbjct: 63 HSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEA 122 Query: 83 KYEEVPRKLVIIEGDLECTEERAELAESRCQE---TDEQIRLMDQNLKCLSDAEEKYSQK 139 + ++ R + +LE E + + +E T +++L L+ SD KY +K Sbjct: 123 EKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQA-SDVSVKYREK 181 Query: 140 EDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 E+E+ + E + + E L EK + LE LKCN E Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILE--LKCNLE 227
Score = 30.0 bits (66), Expect = 0.56 Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 11/115 (9%) Query: 79 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD--AEEKY 136 E++++Y E+ ++L ++ER CQ ++ ++ LK L++ E + Sbjct: 49 ESEQQYFEIEKRL-------SHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEI 101 Query: 137 SQKEDIYEEEIKILTDKLKEAETR--AEFTERLVAKLEKTTDDLEYKLKCNKEEN 189 +Q +I + T + EAE R ERL +LE T+D++ + KE N Sbjct: 102 AQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESN 156
Score = 28.1 bits (61), Expect = 2.1 Identities = 18/81 (22%), Positives = 41/81 (50%), Gaps = 11/81 (13%) Query: 110 SRCQETDEQIRLMDQNLKC-----------LSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 S+ ++T+EQ+ + + LK ++ EE ++++ + EE K + +LKE+ Sbjct: 939 SQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESA 998 Query: 159 TRAEFTERLVAKLEKTTDDLE 179 E+ + ++EK +L+ Sbjct: 999 EFQTQLEKKLMEVEKEKQELQ 1019
Score = 28.1 bits (61), Expect = 2.1 Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 10/116 (8%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q+ K E + E++ KL E E++A + E E + I+L + Sbjct: 237 EEQMNGLKTSNEHLQKHVEDLLTKLK------EAKEQQASMEEKFHNELNAHIKLSNLYK 290 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 D+E K ++ EE K+ LKEA + + + ++E++ D +E ++ Sbjct: 291 SAADDSEAKSNELTRAVEELHKL----LKEAGEANKAIQDHLLEVEQSKDQMEKEM 342
Score = 26.9 bits (58), Expect = 4.7 Identities = 22/101 (21%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Query: 94 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 I L+ +R E+ + + +I + + + L+ +K Q + ++++ +K Sbjct: 714 ISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEK 773 Query: 154 LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 194 L AE RAE ++ L+ + E +L +E L QR Sbjct: 774 LAVAEVRAENLKKEKEMLKLS----EVRLSQQRESLLAEQR 810
Score = 26.9 bits (58), Expect = 4.7 Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE--EEIKILTDKLKEAETRAEFTER 166 ES Q + + RL + +++ E S + ++ + ++K LT+K KE E + Sbjct: 49 ESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIA 108 Query: 167 LVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE 205 + ++ +T ++LE K + + T L Q L L E Sbjct: 109 IQSQFTRTKEELE----AEKRDLIRTNERLSQELEYLTE 143
>gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9 (Protein kinase A anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120 like protein) (Hyperion protein) (Yotiao protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) Length = 3911 Score = 35.8 bits (81), Expect = 0.010 Identities = 31/130 (23%), Positives = 62/130 (47%), Gaps = 18/130 (13%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 +L+E H E R E++ +L EG ++ + L E + QE + I ++Q L C Sbjct: 1910 ELRERLH---EESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLC 1966 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA--------EFTERLV-------AKLEK 173 S+ ++ ++ +EE ++L+ + + + A + TE+L+ + EK Sbjct: 1967 ASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEK 2026 Query: 174 TTDDLEYKLK 183 DDL+ ++K Sbjct: 2027 VRDDLQKQVK 2036
Score = 35.4 bits (80), Expect = 0.013 Identities = 36/162 (22%), Positives = 75/162 (46%), Gaps = 19/162 (11%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 RD + + KE ++ E+ ++ EE+ K ++ E + + + +R QE +++ +L Sbjct: 2207 RDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLF 2266 Query: 123 DQNLKCL------SDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 +++ L SDA Q ++ + +I+ +K E + E +L +L+ TTD Sbjct: 2267 KDDMEKLGLAIKESDAMSTQDQHV-LFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTD 2325 Query: 177 ------------DLEYKLKCNKEENLCTQRMLYQTLLDLNEM 206 DLE +++C + C +R + + LNE+ Sbjct: 2326 NKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEV 2367
Score = 35.0 bits (79), Expect = 0.017 Identities = 50/232 (21%), Positives = 90/232 (38%), Gaps = 31/232 (13%) Query: 6 TMEEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDM 65 T + K +IQ Q QA + A++++ T Q+L + Sbjct: 244 TEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKK 303 Query: 66 KEIQLK------EAKHIAEEADRKYE-----EVPRKLVIIEG-DLECTEERAELAESRCQ 113 ++ ++ + K E D+K E E+ K IIE + + EE + E + + Sbjct: 304 EDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDK 363 Query: 114 ---------ETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR---- 160 E EQI +Q +K + QKE EEIK L ++E + R Sbjct: 364 LTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKD 423 Query: 161 AEFTERLVAKLEKTTDDLEYKLKCNKEENL------CTQRMLYQTLLDLNEM 206 ++F +V ++E+ T +L+ +E Q ++ Q + + EM Sbjct: 424 SQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEM 475
Score = 33.9 bits (76), Expect = 0.039 Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 15/147 (10%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL--- 126 +KE + +A++ +++ +++ +E D+E E+ + E ++ E + L QN Sbjct: 2014 MKEKLEVQCQAEKVRDDLQKQVKALEIDVE--EQVSRFIELEQEKNTELMDLRQQNQALE 2071 Query: 127 -------KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 K L + + D++++EI+ L +LK +E ++E+ + L+ Sbjct: 2072 KQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLK 2131 Query: 180 YKL-KCNKEENLCTQRMLYQTLLDLNE 205 K KC+ E L ++ L + + + NE Sbjct: 2132 EKTDKCS--ELLLSKEQLQRDIQERNE 2156
Score = 30.4 bits (67), Expect = 0.43 Identities = 35/152 (23%), Positives = 70/152 (46%), Gaps = 23/152 (15%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 M E+Q+ E + + A E++ + +++ E ++ELA+++ E + ++ + Sbjct: 3137 MLEMQV-ELSSMKDRATELQEQLSSEKMVV------AELKSELAQTKL-ELETTLKAQHK 3188 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE----FTERLVAKLEKTTD---- 176 +LK L + K D E+ +L D L + ++ E+ AKL ++ + Sbjct: 3189 HLKELEAFRLEVKDKTD----EVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKE 3244 Query: 177 ---DLEYKLKCNKEENLCTQRMLYQTLLDLNE 205 DL++ L+ K+ NL +L Q LNE Sbjct: 3245 ELEDLKFSLESQKQRNLQLNLLLEQQKQLLNE 3276
Score = 28.9 bits (63), Expect = 1.2 Identities = 22/122 (18%), Positives = 57/122 (46%), Gaps = 6/122 (4%) Query: 76 IAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 I +E + + +++ ++ ++ L+ T + + +E +E IR ++ ++CL +E Sbjct: 2298 IIQEKEVEIDQLNEQVTKLQQQLKITTDNKVI-----EEKNELIRDLETQIECLMSDQEC 2352 Query: 136 YSQKEDIYEEEIKILTDKL-KEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 194 + + E++ + +KL +E + T L + D L+++L E L ++ Sbjct: 2353 VKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQ 2412 Query: 195 ML 196 + Sbjct: 2413 QV 2414
>gi|57015410|sp|Q8NDV3|SM1L2_HUMAN Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein) Length = 1235 Score = 35.8 bits (81), Expect = 0.010 Identities = 32/127 (25%), Positives = 60/127 (47%), Gaps = 13/127 (10%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 +++ QL K + E+ +K + ++L ++ + + EER + R E + Sbjct: 366 ELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRHGE-------VQ 418 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 NLK + + E + ++ + EE K D LKE + + E LV ++EKT + + Sbjct: 419 GNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQ---EETLVDEIEKTKSRMS---E 472 Query: 184 CNKEENL 190 N+E NL Sbjct: 473 FNEELNL 479
Score = 27.3 bits (59), Expect = 3.6 Identities = 21/99 (21%), Positives = 51/99 (51%), Gaps = 10/99 (10%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-----ERAELAESRCQETDEQI 119 +K L ++I + +++ + R+L E +L+ E +R + +++ + T + Sbjct: 251 VKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKAK-ENTSHHL 309 Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 + +D K + D+E++ S++ED +IK L +L + + Sbjct: 310 KKLDVAKKSIKDSEKQCSKQED----DIKALETELADLD 344
>gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 Length = 586 Score = 35.4 bits (80), Expect = 0.013 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 15/121 (12%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEER-----AELAESRCQETDEQIRL 121 +I+L+E + D +EGDLE +++ A LA ++ Q DE + Sbjct: 132 QIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAAKKQLADETLLK 191 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 +D +C S E+ +K +YEEEI ETR + RLV + EYK Sbjct: 192 VDLENRCQSLTEDLEFRK-SMYEEEIN---------ETRRKHETRLVEVDSGRQIEYEYK 241 Query: 182 L 182 L Sbjct: 242 L 242
>gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain containing protein 2) Length = 1411 Score = 35.4 bits (80), Expect = 0.013 Identities = 33/155 (21%), Positives = 73/155 (47%), Gaps = 17/155 (10%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVI------IEGDLECTEERAELAESRCQETDE 117 ++K +L+ K I D K + +KL + ++ +E + ++ + + ++ +E Sbjct: 1146 ELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEE 1205 Query: 118 QIR--LMDQNLKCLSDAEEKYSQKEDIYEEEIKI------LTDKLKEAETRAEFTERLVA 169 +++ +++ K S+ +EK + E E K+ L + L + + ++R V+ Sbjct: 1206 ELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVS 1265 Query: 170 KLEKTTDDLEYK---LKCNKEENLCTQRMLYQTLL 201 +LEK TDDL + L+ + N +R L + L Sbjct: 1266 ELEKQTDDLRGEIAVLEATVQNNQDERRALLERCL 1300
Score = 31.6 bits (70), Expect = 0.19 Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 19/164 (11%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC 100 Q++LT A Q+L + ++ Q + ++ R+ E L+ DL+ Sbjct: 997 QQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESE-----LLATRQDLKS 1051 Query: 101 TEERAELAE----SRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTD---- 152 EE+ LA+ S + Q +L+ + + E+ ++KE +E K L D Sbjct: 1052 VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKE 1111 Query: 153 -KLKEAE-----TRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 LKE E ++ E + + EK L +LK +K E++ Sbjct: 1112 KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESI 1155
Score = 30.4 bits (67), Expect = 0.43 Identities = 38/144 (26%), Positives = 67/144 (46%), Gaps = 25/144 (17%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGD---LECTEERA--ELAESRCQETDEQIRL 121 E LKE K ++K EE+ ++ +E D ++ ++E+A +L + R TD ++R Sbjct: 708 ESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRA 767 Query: 122 MDQN----------------LKCLSDAEEKYSQKEDIYEEEIKILTDKLK--EAETRAEF 163 + + L+ S+A E QK EEE +IL + ET+ + Sbjct: 768 TELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQH 827 Query: 164 TERLVAKLEKTTDDLEYKLKCNKE 187 E L +++ T +L+ K+K KE Sbjct: 828 -EELNNRIQTTVTELQ-KVKMEKE 849
Score = 28.1 bits (61), Expect = 2.1 Identities = 29/134 (21%), Positives = 56/134 (41%), Gaps = 3/134 (2%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E QLKE + E + ++ ++ + + T + A++ ++ QI DQ + Sbjct: 466 EEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKI 525 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK---LEKTTDDLEYKLK 183 + L +K + + E+E + L K++ E +L K L++ L KLK Sbjct: 526 QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLK 585 Query: 184 CNKEENLCTQRMLY 197 E + Q L+ Sbjct: 586 NQSESHKQAQENLH 599
Score = 26.6 bits (57), Expect = 6.2 Identities = 24/135 (17%), Positives = 56/135 (41%), Gaps = 24/135 (17%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 K+I ++ + +++E ++EE+ ++ +L+ + E + +++ + + Sbjct: 809 KQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS 868 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 LK EK +QK + + LEKT +L+++L+ Sbjct: 869 LKNSKSEFEKENQK------------------------GKAAILDLEKTCKELKHQLQVQ 904 Query: 186 KEENLCTQRMLYQTL 200 E L Q+ L ++L Sbjct: 905 MENTLKEQKELKKSL 919
>gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 1) (PTPRF-interacting protein alpha 1) (LAR-interacting protein 1) (LIP.1) Length = 1202 Score = 35.4 bits (80), Expect = 0.013 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 3/141 (2%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 K QL+E +AE+ ++ L +E +L AE R +E++R M+ Sbjct: 363 KNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQ 422 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 L+ + ++ Q+E + EE K L+D + + +E ERL L++ LE K Sbjct: 423 LEEKNQELQRARQREKMNEEHNKRLSDTVD--KLLSESNERLQLHLKERMAALEDKNSLL 480 Query: 186 KEENLCTQRMLYQTLLDLNEM 206 +E ++ L +T D +++ Sbjct: 481 REVE-SAKKQLEETQHDKDQL 500
Score = 33.1 bits (74), Expect = 0.066 Identities = 32/155 (20%), Positives = 67/155 (43%), Gaps = 8/155 (5%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMK-----EIQLKEAKHIAEEADRKYEEVPRKLVIIE 95 +ER+TT L+K D+ EI K++ H + + K ++ +L + E Sbjct: 319 EERITT-LEKRYLAAQREATSVHDLNDKLENEIANKDSMH--RQTEDKNRQLQERLELAE 375 Query: 96 GDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK 155 L+ T +AE E +++ + + + + EE+ Q E EE+ + L + Sbjct: 376 QKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQ 435 Query: 156 EAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 + E +RL ++K + +L+ + +E + Sbjct: 436 REKMNEEHNKRLSDTVDKLLSESNERLQLHLKERM 470
Score = 32.0 bits (71), Expect = 0.15 Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 7/125 (5%) Query: 72 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 131 E + I + R+ ++ +L + + EE + A + I+ + N K D Sbjct: 254 ELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARK------DLIKSEEMNTKLQRD 307 Query: 132 AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLC 191 E +QKED+ EE I L + A+ A L KLE + + + +++N Sbjct: 308 VREAMAQKEDM-EERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQ 366 Query: 192 TQRML 196 Q L Sbjct: 367 LQERL 371
>gi|17373489|sp|Q13111|CAF1A_HUMAN Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150) Length = 938 Score = 35.0 bits (79), Expect = 0.017 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 9/102 (8%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R+ KE +EAK EEA +K EE E +L+ +ER E E +E E+ RL Sbjct: 336 REEKEKLKEEAKRAKEEAKKKKEE--------EKELK-EKERREKREKDEKEKAEKQRLK 386 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFT 164 ++ K +A E +++ EEE ++ ++ + +AE T Sbjct: 387 EERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 428
>gi|28380824|sp|Q9Y3A5|SBDS_HUMAN Shwachman-Bodian-Diamond syndrome protein (CGI-97) Length = 250 Score = 35.0 bits (79), Expect = 0.017 Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 12/95 (12%) Query: 115 TDEQIRLMDQNLKC----LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK 170 TD+Q + Q L +SD +E+++Q E ++ + I+ DK ET+ +T V Sbjct: 77 TDDQTEICKQILTKGEVQVSD-KERHTQLEQMFRDIATIVADKCVNPETKRPYT---VIL 132 Query: 171 LEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLNE 205 +E+ D+ Y +K NK T++ + + L E Sbjct: 133 IERAMKDIHYSVKTNKS----TKQQALEVIKQLKE 163
>gi|20140696|sp|Q96AA8|Y555_HUMAN Hypothetical protein KIAA0555 Length = 810 Score = 35.0 bits (79), Expect = 0.017 Identities = 27/101 (26%), Positives = 52/101 (51%), Gaps = 3/101 (2%) Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 +ER EL + R +ET++Q + + + KCL+ ++ EE++K +T + +E R Sbjct: 307 DERNELLK-RVRETEKQCKPLLERNKCLAKRNDELMVSLQRMEEKLKAVTK--ENSEMRE 363 Query: 162 EFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 202 + T K K+ +DL+ + + E L Q + Q ++D Sbjct: 364 KITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQNIID 404
>gi|57015279|sp|O14578|CTRO_HUMAN Citron Rho-interacting kinase (CRIK) (Rho-interacting, serine/threonine kinase 21) Length = 2027 Score = 35.0 bits (79), Expect = 0.017 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 18/141 (12%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 129 L+ + E A+R+ E++ + EG + E EL E +E + ++ +LK Sbjct: 659 LQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKH-REAQVSAQHLEVHLK-- 715 Query: 130 SDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD-----LEYKLKC 184 QKE YEE+IK+L +++K+ E E ++ + E+ + E K Sbjct: 716 --------QKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMI 767 Query: 185 NKEENLCTQRMLYQTLLDLNE 205 N ++ R L Q +++L+E Sbjct: 768 NAMDSKI--RSLEQRIVELSE 786
Score = 31.6 bits (70), Expect = 0.19 Identities = 43/220 (19%), Positives = 79/220 (35%), Gaps = 32/220 (14%) Query: 9 EVKCKIQVLQQQADDXXXXXXXXXXXXXX-DHAQERLTTALQKLXXXXXXXXXXXRDMKE 67 E + KIQ LQ++ + A+ER L+KL + + E Sbjct: 633 EQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVE 692 Query: 68 IQLKEAKHIAEEADRKYEEV---------PRKLVIIE-------GDLECTEERAELAESR 111 + E KH + ++ EV K+ +++ D E E + E Sbjct: 693 AEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEE 752 Query: 112 CQE--------------TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 E D +IR ++Q + LS+A + + + +K + + E Sbjct: 753 AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISEL 812 Query: 158 ETRAEFTERLVAKLEKTTDDLEYKL-KCNKEENLCTQRML 196 + + E KLE LE +L K + +++ R+L Sbjct: 813 RQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLL 852
>gi|51338794|sp|P78559|MAP1A_HUMAN Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2] Length = 2805 Score = 35.0 bits (79), Expect = 0.017 Identities = 30/134 (22%), Positives = 60/134 (44%), Gaps = 6/134 (4%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 + K+ L++ E D+ EE + L E + EE+ + E + +++ + ++ Sbjct: 1416 EQKDTALEQKDKALEPKDKDLEEKDKAL---EQKDKIPEEKDKALEQKDTALEQKDKALE 1472 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA---EFTERLVAKLEKTTDDLEY 180 K L + QKE I EE+ K L K++ E +A E LE+T E Sbjct: 1473 PKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQ 1532 Query: 181 KLKCNKEENLCTQR 194 K + ++++ +++ Sbjct: 1533 KHQAQEQKDKVSEK 1546
Score = 33.1 bits (74), Expect = 0.066 Identities = 34/139 (24%), Positives = 59/139 (42%), Gaps = 11/139 (7%) Query: 46 TALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERA 105 TA+ KL ++ + KE ++A E+ P K ER Sbjct: 329 TAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEK--------PAKPERV 380 Query: 106 ELAESRCQETDEQIRLMDQ-NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFT 164 + S + +++ + D+ K L + K +K+D ++EIK +LK+ E R E Sbjct: 381 KTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKE-- 438 Query: 165 ERLVAKLEKTTDDLEYKLK 183 E+ AK E+ D + +LK Sbjct: 439 EKKDAKKEEKRKDTKPELK 457
Score = 30.8 bits (68), Expect = 0.33 Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 13/127 (10%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 +D Q EA H+ EA ++ ++ E++ E + +++ + + Sbjct: 1383 KDTAIYQKDEALHVKNEAVKQQDKA-------------LEQKGRDLEQKDTALEQKDKAL 1429 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 + K L + ++ QK+ I EE+ K L K E + + E LE+ LE K Sbjct: 1430 EPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKE 1489 Query: 183 KCNKEEN 189 K +E++ Sbjct: 1490 KIPEEKD 1496
Score = 29.6 bits (65), Expect = 0.73 Identities = 22/99 (22%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 63 RDMKEI-QLKEAKHIAEE-----ADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD 116 RD+++ + E KH A+E +++K + + +K + E E+ + E Q + Sbjct: 1521 RDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK 155 ++ + + + EEK +K EE+++ L +K K Sbjct: 1581 QESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTK 1619
>gi|14195666|sp|O60841|IF2P_HUMAN Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2) Length = 1220 Score = 35.0 bits (79), Expect = 0.017 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Query: 78 EEADRKYEE--VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 +E+ RK+EE V K+ + G + +EE+AE + + + + D+ K E++ Sbjct: 270 KESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKE 329 Query: 136 YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 +K+ + +K + + L + + E +R + K ++LE K K +EE L Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK--EEERL 382
Score = 33.5 bits (75), Expect = 0.051 Identities = 29/117 (24%), Positives = 58/117 (49%), Gaps = 14/117 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D K+ K+ K EE +++ ++ P K + + E + E E + +E +E+I+ ++ Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATV-KAMQEALAKLKEEEERQKREEEERIKRLE 370 Query: 124 QNLKCLSDAEEKYSQ------------KEDIYEEEIKILTDKLKEAETRAEFTERLV 168 + L+ EE+ Q +++ ++E K+LT +EA RAE T +L+ Sbjct: 371 E-LEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLL 426
Score = 26.9 bits (58), Expect = 4.7 Identities = 23/100 (23%), Positives = 46/100 (46%), Gaps = 3/100 (3%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 + ++L A + E+ + EE P +E + E E A L + +DE+ ++ N Sbjct: 465 ESMELCAAVEVMEQGVPEKEETPPP---VEPEEEEDTEDAGLDDWEAMASDEETEKVEGN 521 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 + E ++E+ EEE +++ +E E +E +E Sbjct: 522 TVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
>gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit associated protein 2 (CDK5 activator-binding protein C48) Length = 1893 Score = 35.0 bits (79), Expect = 0.017 Identities = 29/123 (23%), Positives = 54/123 (43%), Gaps = 14/123 (11%) Query: 76 IAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 + +E DR EE+ L E ++C +E E ++ C DE + + C + EEK Sbjct: 215 VLDEKDRLIEELKLSLKSKEALIQCLKE--EKSQMACP--DENVSSGELRGLCAAPREEK 270 Query: 136 ----------YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN 185 + ++ + +EE I+ L + L+E E ++ K +K L LK Sbjct: 271 ERETEAAQMEHQKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSK 330 Query: 186 KEE 188 +++ Sbjct: 331 EKK 333
>gi|47605999|sp|Q13464|ROCK1_HUMAN Rho-associated protein kinase 1 (Rho-associated, coiled-coil containing protein kinase 1) (p160 ROCK-1) (p160ROCK) Length = 1354 Score = 34.7 bits (78), Expect = 0.023 Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 32/150 (21%) Query: 69 QLKEAKHIAEEADR----KYEEVPRKLVIIEGDLECTEERAE--------LAESRCQETD 116 Q+KE K EE +R K +E+ + + L+ E +AE L E + T Sbjct: 859 QVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQ 918 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKED----------IYEEEIKILTDKLKEAETRAEFTER 166 E + +N + ++D + S+ E+ I E + LT+K+K+AE Sbjct: 919 ESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEE------ 972 Query: 167 LVAKLEKTTDDLEYKLKCNKEENLCTQRML 196 KLEK ++ LK E+N+ T+R L Sbjct: 973 --YKLEK--EEEISNLKAAFEKNINTERTL 998
Score = 33.1 bits (74), Expect = 0.066 Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 7/96 (7%) Query: 86 EVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIY 143 E + + + E + + EER E AE+R + ++Q ++D +LK E + ++ Sbjct: 706 EEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERM 765 Query: 144 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 E+E+K LT +L++ E +RL+ + E T E Sbjct: 766 EDEVKNLTLQLEQ-----ESNKRLLLQNELKTQAFE 796
Score = 30.0 bits (66), Expect = 0.56 Identities = 23/109 (21%), Positives = 53/109 (48%), Gaps = 12/109 (11%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E +LKE + E+A+ + ++ ++ +++ DL+ ++++ E + +++++ + L Sbjct: 717 EKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQL 776 Query: 127 KCLSDAEEKYSQKEDIYEEEIK---ILTDKLK--EAETRAEFTERLVAK 170 E+ S K + + E+K D LK E + + E L AK Sbjct: 777 -------EQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAK 818
>gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein-170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament associated protein) Length = 1427 Score = 34.7 bits (78), Expect = 0.023 Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 36/169 (21%) Query: 63 RDMKEIQLK--------------------EAKHIAEEADRKYEE----VPRKLVIIEGDL 98 RD++E+QLK +A+ +EA +K+EE + RKL +E + Sbjct: 945 RDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKM 1004 Query: 99 ECTEERAELAESRCQ----ETDEQIRLMDQNL-KCLSDAEEKYSQKEDIYE------EEI 147 E + + + ++R + ET + + QNL K L D E+K + EE+ Sbjct: 1005 ETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEEL 1064 Query: 148 KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRML 196 + DK K A+T AE +++ ++ K + L+ K+ N Q L Sbjct: 1065 RKQADKAKAAQT-AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1112
Score = 34.3 bits (77), Expect = 0.030 Identities = 36/154 (23%), Positives = 65/154 (42%), Gaps = 27/154 (17%) Query: 63 RDMKEIQLKEAKHIAE----EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ 118 +D +E QL +AK E E + + +L + +L E E + + + +E Sbjct: 901 KDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANEN 960 Query: 119 IRLMDQNLKCLS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFT------------- 164 + ++++ ++ AE+ + +EEE K L KL + E + E + Sbjct: 961 ASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYER 1020 Query: 165 ---------ERLVAKLEKTTDDLEYKLKCNKEEN 189 E ++ L+KT D E KLK +EEN Sbjct: 1021 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREEN 1054
Score = 30.0 bits (66), Expect = 0.56 Identities = 26/151 (17%), Positives = 71/151 (47%), Gaps = 3/151 (1%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQ--LKEAKHIAEEADRKYEEVPRKLVIIEGDL 98 Q + + KL D+++++ L + + E D + E++ + +E D+ Sbjct: 860 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 919 Query: 99 ECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 + + S+ + ++++RL +++++ L K ++ ++ I+ +T K ++++ Sbjct: 920 AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ 979 Query: 159 TR-AEFTERLVAKLEKTTDDLEYKLKCNKEE 188 A+ E +LE+ DLE K++ + + Sbjct: 980 QEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1010
>gi|23396633|sp|Q15058|KF14_HUMAN Kinesin-like protein KIF14 Length = 1648 Score = 34.7 bits (78), Expect = 0.023 Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 19/131 (14%) Query: 81 DRKYEEVPRKLVIIEGDL---ECTEERAELAESRCQETDEQIRLMDQNLKCLSD-AEEKY 136 D E P+ + +L + ++ AE+ E++ + +E M Q ++ + A+++ Sbjct: 914 DTPISEGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAKEE----MMQGIQIAKEMAQQEL 969 Query: 137 SQKEDIYEEEIKILTDKLKEAETRAEFTE-------RLVAKLEKTTDDLEYKLKCNKE-- 187 S ++ YE +IK L +L+E R + E + +LEK LE ++ NK+ Sbjct: 970 SSQKAAYESKIKALEAELREESQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRL 1029 Query: 188 --ENLCTQRML 196 E L T++ L Sbjct: 1030 EMETLATKQAL 1040
>gi|20137264|sp|O60239|3BP5_HUMAN SH3 domain-binding protein 5 (SH3 domain-binding protein that preferentially associates with BTK) Length = 425 Score = 34.7 bits (78), Expect = 0.023 Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 23/140 (16%) Query: 72 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ------IRLMDQN 125 EA+ +A +A + ++ + L +E LAE R E D++ +++ Sbjct: 73 EARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHA 132 Query: 126 LKCLSDAEEKYSQKEDIYEE----------EIKILTDKLKEAETRAEFTERLVAK----- 170 + + +AE+ ++ E +++E ++ L KLK A +++ L AK Sbjct: 133 TQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQL 192 Query: 171 --LEKTTDDLEYKLKCNKEE 188 L+KT DDL+ KL K E Sbjct: 193 EQLKKTVDDLQAKLTLAKGE 212
>gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin Length = 1197 Score = 34.7 bits (78), Expect = 0.023 Identities = 34/141 (24%), Positives = 67/141 (47%), Gaps = 23/141 (16%) Query: 88 PRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA--EEKYSQKEDI--- 142 P K V+++ LE E E+ E + Q +EQ+RL ++ L L A EE S+ +++ Sbjct: 454 PAKEVLLKDLLETRELLEEVLEGK-QRVEEQLRLRERELTALKGALKEEVASRDQEVEHV 512 Query: 143 ---YEEEIKILTDKLKEA-----------ETRAEFTERLVAKLEKTTDDL---EYKLKCN 185 Y+ + + L +++A + + L +LE+T+++ + + N Sbjct: 513 RQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKN 572 Query: 186 KEENLCTQRMLYQTLLDLNEM 206 KE+ T++ L Q ++ EM Sbjct: 573 KEDLRATKQELLQLRMEKEEM 593
Score = 29.6 bits (65), Expect = 0.73 Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 12/114 (10%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK-- 135 EEA R + ++ + LE ++ E+ E +EQ RL+D+ + L+ EK Sbjct: 797 EEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIG 856 Query: 136 ----------YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 +Q ED E+ + + D ++A+ A E+ L + D+++ Sbjct: 857 EDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQ 910
Score = 29.3 bits (64), Expect = 0.95 Identities = 18/70 (25%), Positives = 32/70 (45%), Gaps = 3/70 (4%) Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE---IKILTDKLKEAETRAEFTERLVA 169 QE + + R D + L EEK S+ E +EE +++LTD++ + + + Sbjct: 942 QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELM 1001 Query: 170 KLEKTTDDLE 179 + DLE Sbjct: 1002 QERSARQDLE 1011
>gi|27734271|sp|Q8TDM6|DLG5_HUMAN Discs, large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg) Length = 1809 Score = 34.7 bits (78), Expect = 0.023 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 14/104 (13%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGD-----LECTEERAELAESRCQETDEQIRLMDQN 125 KE++ EE D Y E KL++ E D L+ + ELAES+ + + + + ++ Sbjct: 306 KESEKYREERDAVYSEY--KLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEE 363 Query: 126 LKCLSDAEE-------KYSQKEDIYEEEIKILTDKLKEAETRAE 162 ++ L ++ + +++ +I ++ K L +LKEA A+ Sbjct: 364 MEALRQIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEAD 407
>gi|1169540|sp|P42566|EP15_HUMAN Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein) Length = 896 Score = 34.3 bits (77), Expect = 0.030 Identities = 20/95 (21%), Positives = 47/95 (49%) Query: 94 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 +E DL+ E+ + S Q+ ++++ + NL+ L +++ + D +E+ L ++ Sbjct: 352 VEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQ 411 Query: 154 LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 LKE + +L++ L+ E ++ +EE Sbjct: 412 LKEVRKKCAEEAQLISSLKAELTSQESQISTYEEE 446
>gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor) (CG-1 antigen) Length = 1357 Score = 33.9 bits (76), Expect = 0.039 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 7/120 (5%) Query: 74 KHIAEEADRKYEEVPRKLVIIE-----GDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 K + E+ ++ +E KL +E G ++ + EL R + + + D LK Sbjct: 727 KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQD--LKA 784 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 + + ++ + ++ I K+K E E VA EKT DL+ ++K KEE Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 844
Score = 32.3 bits (72), Expect = 0.11 Identities = 39/153 (25%), Positives = 67/153 (43%), Gaps = 30/153 (19%) Query: 66 KEIQLKEAKH-IAEEADR---KYEEVP-------------RKLVIIEGDLECTEERAELA 108 K+ Q+K+ + +A E DR K EE+ +KL + + E Sbjct: 612 KDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKM 671 Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV 168 + D++IRL+++ L + + S K EE KIL D+ K ++ + + LV Sbjct: 672 QQSVYVKDDKIRLLEEQL------QHEISNKM----EEFKILNDQNKALKSEVQKLQTLV 721 Query: 169 AKLEKTTDDLEYKLKC--NKEENLCTQRMLYQT 199 ++ + D +E KC K+E L T L +T Sbjct: 722 SE-QPNKDVVEQMEKCIQEKDEKLKTVEELLET 753
Score = 27.7 bits (60), Expect = 2.8 Identities = 23/106 (21%), Positives = 49/106 (46%), Gaps = 18/106 (16%) Query: 66 KEIQLKEAKHIA-------EEADRKYEEVP---RKLVI--------IEGDLECTEERAEL 107 +E+Q K A+ A +EA+R++EEV RK ++ E + Sbjct: 472 EEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQS 531 Query: 108 AESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 S+ +T + ++Q L L ++E+K KE+ + +++ + ++ Sbjct: 532 LHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Score = 26.6 bits (57), Expect = 6.2 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 14/59 (23%) Query: 145 EEIKILTDKLKEAETRAEF--------------TERLVAKLEKTTDDLEYKLKCNKEEN 189 EE+K+L KLKEA+ TE ++ KL+++ + E K K +E+ Sbjct: 1113 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDES 1171
>gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1 protein) Length = 2230 Score = 33.9 bits (76), Expect = 0.039 Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 2/115 (1%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAE 133 K+ ++ D +++E+ +KL + E + R + AE + + Q+ M L+ Sbjct: 1549 KNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKEL 1608 Query: 134 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 E + EEE+K L D+L E+E+ A+ E L K E+ ++ +L EE Sbjct: 1609 EHVNLSVKSKEEELKALEDRL-ESESAAKLAE-LKRKAEQKIAAIKKQLLSQMEE 1661
Score = 33.9 bits (76), Expect = 0.039 Identities = 33/143 (23%), Positives = 65/143 (45%), Gaps = 24/143 (16%) Query: 67 EIQLKEAKHIAEEADRKYEEVP---RKLVIIEGDLECTEERAELAES-----------RC 112 E++ KEA E+ + EE+ ++ ++G++E + + E ES R Sbjct: 1468 ELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARI 1527 Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKL-------KEAETRAEFTE 165 E ++ I ++ L++ + Y+Q++DI E K L KL +E + R + E Sbjct: 1528 MELEDHITQKTIEIESLNEVLKNYNQQKDI---EHKELVQKLQHFQELGEEKDNRVKEAE 1584 Query: 166 RLVAKLEKTTDDLEYKLKCNKEE 188 + LE ++ +L+ K+E Sbjct: 1585 EKILTLENQVYSMKAELETKKKE 1607
Score = 33.1 bits (74), Expect = 0.066 Identities = 28/105 (26%), Positives = 53/105 (50%), Gaps = 15/105 (14%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 144 +E ++ I E + E AEL ES +ET++ ++ + + L ++Y + D E Sbjct: 2008 KEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2067 Query: 145 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEEN 189 EE +T K+++ +T+ E +L+K +Y+ K +EEN Sbjct: 2068 EE---MTAKVRDLQTQLE-------ELQK-----KYQQKLEQEEN 2097
Score = 31.6 bits (70), Expect = 0.19 Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 16/130 (12%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 K+ L A+H+ +E + + + L + D++ T + EL CQ +++I+ +D Sbjct: 1806 KKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT---CQILEQKIKELDSC 1862 Query: 126 LKC--------LSDAEEKYS-----QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE 172 L + + KY Q+ D + ++L + +E +L++ +E Sbjct: 1863 LVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNME 1922 Query: 173 KTTDDLEYKL 182 +DLE+KL Sbjct: 1923 AQHNDLEFKL 1932
Score = 31.2 bits (69), Expect = 0.25 Identities = 26/140 (18%), Positives = 53/140 (37%), Gaps = 31/140 (22%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEG-------DLECTEERAELAESRCQETDEQIRL 121 +L+ + + EE D + +E K++ +E +LE ++ E + +E+++ Sbjct: 1565 KLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624 Query: 122 MDQNL------------------------KCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 ++ L + LS EEK Q + E + L KL+E Sbjct: 1625 LEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQER 1684 Query: 158 ETRAEFTERLVAKLEKTTDD 177 E E + +E + + Sbjct: 1685 EREVHILEEKLKSVESSQSE 1704
Score = 31.2 bits (69), Expect = 0.25 Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 6/122 (4%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E+ LKE +E E + + EG+L+ + ++ +S T EQ + ++ L Sbjct: 762 ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL 821 Query: 127 -----KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 K L E+ + + E E + D E + + L+ +LEK ++E K Sbjct: 822 AQLQQKLLDLETERILLTKQVAEVEAQ-KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQK 880 Query: 182 LK 183 +K Sbjct: 881 VK 882
Score = 29.3 bits (64), Expect = 0.95 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 5/139 (3%) Query: 40 AQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAE-EADRKYEEVPRKLVIIEGDL 98 ++E + Q+L + E Q+ + + + E E RK +E+ +KL E + Sbjct: 448 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREF 507 Query: 99 ECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 + E+ ++A + Q +I + + L+ EE QK+ I E L D +EAE Sbjct: 508 Q---EQMKVALEKSQSEYLKISQEKEQQESLA-LEELELQKKAILTESENKLRDLQQEAE 563 Query: 159 TRAEFTERLVAKLEKTTDD 177 T L + LEK+ + Sbjct: 564 TYRTRILELESSLEKSLQE 582
>gi|17433142|sp|Q9HD67|MYO10_HUMAN Myosin X Length = 2058 Score = 33.9 bits (76), Expect = 0.039 Identities = 35/142 (24%), Positives = 63/142 (44%), Gaps = 5/142 (3%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQET--DEQIRLMDQNL 126 QL K EE ++ EE +K E + E AEL + +ET +++ + ++ Sbjct: 810 QLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQ 869 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV--AKLEKTTDDLEYKLKC 184 K E QKE+ EEI L ++++ + E E + A L+K + + +L+ Sbjct: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR- 928 Query: 185 NKEENLCTQRMLYQTLLDLNEM 206 EE C + L+ +E+ Sbjct: 929 RLEEEACRAAQEFLESLNFDEI 950
>gi|6685695|sp|Q9Y6K9|NEMO_HUMAN NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase gamma subunit) (IkB kinase gamma subunit) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3) Length = 419 Score = 33.5 bits (75), Expect = 0.051 Identities = 19/95 (20%), Positives = 44/95 (46%), Gaps = 3/95 (3%) Query: 66 KEIQLKEAKHIAEEADRKYEE---VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 KE L+E +H+ + E+ V ++ + G+L+ ++ R E A CQ + + R Sbjct: 118 KEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAA 177 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 + + L E Q+ + +++++ ++ A Sbjct: 178 SEQARQLESEREALQQQHSVQVDQLRMQGQSVEAA 212
>gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1) Length = 4684 Score = 33.5 bits (75), Expect = 0.051 Identities = 26/110 (23%), Positives = 53/110 (48%), Gaps = 17/110 (15%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 + ++++ K AE+ R+ +V ++L + LE ETD Q L+D+ L Sbjct: 2301 DAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLE--------------ETDHQKNLLDEEL 2346 Query: 127 KCL-SDAEEKYSQKEDIYEE--EIKILTDKLKEAETRAEFTERLVAKLEK 173 + L ++A E Q+ + EE +++ ++L + + R E R + +K Sbjct: 2347 QRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2396
Score = 31.6 bits (70), Expect = 0.19 Identities = 31/107 (28%), Positives = 54/107 (50%), Gaps = 9/107 (8%) Query: 69 QLKEAKHIAEEADR---KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 + ++ K +AEEA R +E R + E DL ++RA LAE +E +++ + + Sbjct: 2406 EAEKMKQVAEEAARLSVAAQEAARLRQLAEEDL--AQQRA-LAEKMLKE---KMQAVQEA 2459 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE 172 + ++AE QKE E+ ++ DK + A+ AE T+ LE Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLE 2506
Score = 30.8 bits (68), Expect = 0.33 Identities = 23/107 (21%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES---RCQETDEQI 119 R + E L + + +AE+ ++ + ++ ++ + E +++ ELA+ R QE EQ+ Sbjct: 2431 RQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQM 2490 Query: 120 RLM----DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 Q + +AE + + E +K+ ++ A+ RAE Sbjct: 2491 AQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAE 2537
Score = 28.5 bits (62), Expect = 1.6 Identities = 23/125 (18%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVII--------------EGDLECTEERAELA 108 R E +++ AE A+R + ++ ++ EG+L+ RAE A Sbjct: 1563 RQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEA 1622 Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV 168 E++ ++ E+ + + ++ D ++ Q E +K + +E + + E L Sbjct: 1623 EAQKRQAQEEAERLRRQVQ---DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELR 1679 Query: 169 AKLEK 173 + E+ Sbjct: 1680 LQAEE 1684
Score = 28.1 bits (61), Expect = 2.1 Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 17/118 (14%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQ-ETDEQIRL 121 R ++E + A+ + EEA+R+ ++ + + E E AE R Q + +E +RL Sbjct: 1731 RSLQEEHVAVAQ-LREEAERRAQQ--------QAEAERAREEAERQLERWQLKANEALRL 1781 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 Q AEE QK E K + +EA R + E+ V + E +LE Sbjct: 1782 RLQ-------AEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1832
Score = 26.9 bits (58), Expect = 4.7 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 18/106 (16%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES--RCQETDEQIRLMDQ 124 E++L + AE+ R E+ +LE +R AE R +E +E+++ Sbjct: 2082 ELELGRIRSNAEDTLRSKEQA---------ELEAARQRQLAAEEERRRREAEERVQ---- 2128 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK 170 K L+ AEE+ +++ EE++ L K++EA + E E+ A+ Sbjct: 2129 --KSLA-AEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESAR 2171
>gi|464541|sp|P35241|RADI_HUMAN Radixin Length = 583 Score = 33.1 bits (74), Expect = 0.066 Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 6/146 (4%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 + ++ QL+ K E A+++ E + R+ + L+ EE+ A+ +E + + Sbjct: 316 KQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALEL 375 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD---LE 179 DQ K + E+ ++ EE + K+A + + E+L A+L + T LE Sbjct: 376 DQERKRAKEEAERLEKERRAAEEAKSAIA---KQAADQMKNQEQLAAELAEFTAKIALLE 432 Query: 180 YKLKCNKEENLCTQRMLYQTLLDLNE 205 K +EE Q + DL + Sbjct: 433 EAKKKKEEEATEWQHKAFAAQEDLEK 458
>gi|14195005|sp|O60437|PEPL_HUMAN Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen) Length = 1756 Score = 33.1 bits (74), Expect = 0.066 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 15/159 (9%) Query: 44 LTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE 103 L L++L R+++ +Q + A EEA+ + + + V+++ D + E Sbjct: 1399 LERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQARE 1458 Query: 104 RA------ELAESRCQETDEQIRLMDQNLKCLSDAE--EKYSQKEDIY------EEEIKI 149 A E + R Q + ++ + + L L AE EK E + E+EI+ Sbjct: 1459 HALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQR 1518 Query: 150 LTDKLKEAETRAEFTERLVAKLEKTTDDLEY-KLKCNKE 187 L L+E + V++LE +LE+ K +KE Sbjct: 1519 LKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKE 1557
Score = 32.0 bits (71), Expect = 0.15 Identities = 38/137 (27%), Positives = 67/137 (48%), Gaps = 14/137 (10%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE----RAELAESRCQE--TDE 117 +++ +QL+ E D E V ++++ IE D +E R EL R Q+ + Sbjct: 970 ELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREA 1029 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEE-IKILTDKLKEAETRA-----EFTERLVAKL 171 ++ L+ Q + L AEEK +E + E+E +K+ D EAE + + ++L K Sbjct: 1030 EVLLLQQRVAAL--AEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ 1087 Query: 172 EKTTDDLEYKLKCNKEE 188 E+ L+ KLK ++E Sbjct: 1088 EEELSFLQDKLKRLEKE 1104
Score = 28.9 bits (63), Expect = 1.2 Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 28/104 (26%) Query: 76 IAEEADRKYEEVPRKLVI-IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEE 134 +AEE R E+V K V+ ++ D + E +L E + Sbjct: 1041 LAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDH----------------------Q 1078 Query: 135 KYSQKEDIYEEEIKILTDKLKEAE-----TRAEFTERLVAKLEK 173 + Q + EEE+ L DKLK E + T + V K+EK Sbjct: 1079 RQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEK 1122
Score = 27.7 bits (60), Expect = 2.8 Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 11/121 (9%) Query: 40 AQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLE 99 A+E++T QK+ + +QL+E +H + + + E + RKL + Sbjct: 1437 AREKVTHT-QKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAAL----- 1490 Query: 100 CTEERAELAESRCQETDEQIRLMD--QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 E+AE+ E Q+ D Q ++ L + E+ S+ + + E+ L +L E Sbjct: 1491 ---EKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSEL 1547 Query: 158 E 158 E Sbjct: 1548 E 1548
>gi|52783153|sp|Q9Y6D9|MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax binding protein-181) Length = 718 Score = 32.7 bits (73), Expect = 0.086 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 8/115 (6%) Query: 72 EAKHIAEEADRKYE-EVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 130 E + A + R YE EV R ++ + +ER AE + QE E+ R QNL Sbjct: 84 ELERAASTSARNYEREVDRNQELLTR-IRQLQEREAGAEEKMQEQLERNRQCQQNLDA-- 140 Query: 131 DAEEKYSQKEDIYE---EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 A ++ +KED E I L ++ E + E V +LE +L+ +L Sbjct: 141 -ASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQL 194
>gi|17375490|sp|Q14203|DYNA_HUMAN Dynactin 1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135) Length = 1278 Score = 32.7 bits (73), Expect = 0.086 Identities = 33/128 (25%), Positives = 66/128 (51%), Gaps = 9/128 (7%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 RD++E +L+ + E K +E+ + + +E + E ++++ E Q+ D Q RL Sbjct: 225 RDLEE-KLETLRLKRAEDKAKLKELEKHKIQLE---QVQEWKSKMQE---QQADLQRRLK 277 Query: 123 D--QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 + + K +A+E+Y ++ + I++ T + AE RAE ++ V L++ D+L Sbjct: 278 EARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTT 337 Query: 181 KLKCNKEE 188 L+ K E Sbjct: 338 DLEILKAE 345
Score = 29.3 bits (64), Expect = 0.95 Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 22/118 (18%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECT----EERAELAESRCQETDEQIRL 121 +E +KE K + + E +L ++E L+ +ER E ++R +ET +R Sbjct: 948 RETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLR- 1006 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAET-RAEFTERLVAKLEKTTDDL 178 +KE +EE + L + + E +AE +RL ++ ++T + L Sbjct: 1007 ----------------KKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRTIEGL 1048
Score = 26.2 bits (56), Expect = 8.1 Identities = 21/104 (20%), Positives = 42/104 (40%), Gaps = 24/104 (23%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 130 +E + + + EE R+L GDLE E + + +ET+ ++R Sbjct: 437 EEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELR---------- 486 Query: 131 DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 E++ + +++EA+ R E + VA ++T Sbjct: 487 --------------EQLDMAGARVREAQKRVEAAQETVADYQQT 516
>gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precursor (Laminin B1 chain) Length = 1786 Score = 32.7 bits (73), Expect = 0.086 Identities = 35/142 (24%), Positives = 65/142 (45%), Gaps = 19/142 (13%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E+ L+EAK ++ A +V +++ LE E+ AE ++ DE I+ QNL Sbjct: 1572 EMLLEEAKRASKSAT----DVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQ-GTQNL 1626 Query: 127 KCLSDAEE--------KYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 ++E SQ+ E ++ L K + AE+ E++V ++++ +D+ Sbjct: 1627 LTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDV 1686 Query: 179 EYKL------KCNKEENLCTQR 194 + L K K ENL ++ Sbjct: 1687 KKTLDGELDEKYKKVENLIAKK 1708
>gi|50400335|sp|Q6UB98|ANRZ_HUMAN Ankyrin repeat domain protein 12 (Ankyrin repeat-containing cofactor-2) (GAC-1 protein) Length = 2062 Score = 32.7 bits (73), Expect = 0.086 Identities = 27/124 (21%), Positives = 64/124 (51%), Gaps = 6/124 (4%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERA-ELAESRCQ-ETDEQIR 120 +++K+ + + KH+++E + K E R + E + EE+ +L E R TD+ Sbjct: 728 KNIKDDKSTKEKHVSKERNFKEE---RDKIKKESEKSFREEKIKDLKEERENIPTDKDSE 784 Query: 121 LMDQNLKCLSDAEEKYSQKEDI-YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 + + ++ + +++I E++ K + + ++ E R++ E+ + K+E+ T + E Sbjct: 785 FTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKE 844 Query: 180 YKLK 183 K+K Sbjct: 845 KKIK 848
Score = 29.6 bits (65), Expect = 0.73 Identities = 32/143 (22%), Positives = 64/143 (44%), Gaps = 14/143 (9%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 RD + I + +KHI EE +K I++G+ E+ L E + DE ++ Sbjct: 965 RDKESINITNSKHIQEE---------KKSSIVDGNKAQHEKPLSLKE---KTKDEPLKTP 1012 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 D K D + ++ D ++++I+I + L + ++ A+ + + K T E +L Sbjct: 1013 DGKEKDKKDKDIDRYKERDKHKDKIQI--NSLLKLKSEADKPKPKSSPASKDTRPKEKRL 1070 Query: 183 KCNKEENLCTQRMLYQTLLDLNE 205 + +RML L++ + Sbjct: 1071 VNDDLMQTSFERMLSLKDLEIEQ 1093
Score = 26.2 bits (56), Expect = 8.1 Identities = 17/64 (26%), Positives = 35/64 (54%), Gaps = 5/64 (7%) Query: 115 TDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 T E+ +++N+K +EK+ KE ++EE DK+K+ E+ F E + L++ Sbjct: 719 TLEKKSKLEKNIKDDKSTKEKHVSKERNFKEE----RDKIKK-ESEKSFREEKIKDLKEE 773 Query: 175 TDDL 178 +++ Sbjct: 774 RENI 777
>gi|2833266|sp|Q15696|U2R2_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related-protein 2 (U2(RNU2) small nuclear RNA auxillary factor 1-like 2) Length = 482 Score = 32.3 bits (72), Expect = 0.11 Identities = 24/96 (25%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM-- 122 ++E QL+E K + E R +EE + + + +E+ E A+ R +E + +++ Sbjct: 53 IEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE 112 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 +Q K + E+K +K++ E K+L E E Sbjct: 113 EQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELE 148
Score = 27.3 bits (59), Expect = 3.6 Identities = 23/87 (26%), Positives = 44/87 (50%), Gaps = 8/87 (9%) Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL----- 171 E+ +L+++ + L E++ +E +EE +I +K + A+ R E ER + + Sbjct: 59 EEEKLLERERQRL---HEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115 Query: 172 EKTTDDLEYKLKCNKEENLCTQRMLYQ 198 K ++ E K + KE+ Q+ML Q Sbjct: 116 RKEREEEEQKRQEKKEKEEALQKMLDQ 142
>gi|462693|sp|P80303|NCB2_HUMAN Nucleobindin 2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4) Length = 420 Score = 32.3 bits (72), Expect = 0.11 Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 22/136 (16%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 +M+E +L+ +H+ E D + +LV +E L+ TE++ L + D+Q + Sbjct: 289 EMEEERLRMREHVMNEVDTNKD----RLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTE 344 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE-YKL 182 + LK +Y + E E+K D+L++ + +L++ D LE KL Sbjct: 345 EELK-------EYENIIALQENELKKKADELQKQK----------EELQRQHDQLEAQKL 387 Query: 183 KCNKEENLCTQRMLYQ 198 + ++ Q+ L Q Sbjct: 388 EYHQVIQQMEQKKLQQ 403
>gi|59799772|sp|O75037|KI21B_HUMAN Kinesin family member 21B Length = 1637 Score = 32.3 bits (72), Expect = 0.11 Identities = 28/115 (24%), Positives = 61/115 (53%), Gaps = 10/115 (8%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEE--RAELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 E+ D EE LV + D E E +A+LA+ C+ +Q +L+D+ L +++ + Sbjct: 608 EDEDSGSEE---SLVDSDSDPEEKEVNFQADLADLTCEIEIKQ-KLIDE----LENSQRR 659 Query: 136 YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 + YEE++ +L +K+++ + + + ++ +E T++ K+K + E+ L Sbjct: 660 LQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRL 714
Score = 29.6 bits (65), Expect = 0.73 Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 20/149 (13%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D E+ ++ AK E +K RK + E ++RA+L + +ETDE + Sbjct: 536 DASEV-IRRAKQDLERLKKKEVRQRRK----SPEKEAFKKRAKLQQENSEETDENEAEEE 590 Query: 124 QNLKCLSDAEE---KYSQKEDIYEEEIKILTD---KLKEAETRAEFTERLVAKLE---KT 174 + + S EE + + ED EE + +D + KE +A+ + L ++E K Sbjct: 591 EEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLAD-LTCEIEIKQKL 649 Query: 175 TDDLEYKLKCNKEENLCTQRMLYQTLLDL 203 D+LE N + L T + Y+ L L Sbjct: 650 IDELE-----NSQRRLQTLKHQYEEKLIL 673
>gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 Length = 363 Score = 32.3 bits (72), Expect = 0.11 Identities = 39/197 (19%), Positives = 81/197 (41%), Gaps = 30/197 (15%) Query: 8 EEVKCKIQVLQQQADDXXXXXXXX-----XXXXXXDHAQE----RLTTALQKLXXXXXXX 58 E+ KCK+ L+QQA+ DH +++T +++L Sbjct: 181 EKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQISTLMRQLQQVKDSQ 240 Query: 59 XXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQ 118 D+ E++ K + ++++ +K +++ +V E + E+ Q+ E Sbjct: 241 QDELDDLGEMRRKVLESLSDKIQKKKKKILSSVV--------AETQRPYEEALLQKMWES 292 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE-----AETRAEFTERLVAKLEK 173 LKC+ +++ + D +EE + +L +++E E R E ++ + K Sbjct: 293 ----QDFLKCM----QRFREIIDQFEENMPVLRAEVEELQAQTREPREVIFEDVLLRRPK 344 Query: 174 TTDDLEYKLKCNKEENL 190 T D++ L EE L Sbjct: 345 CTPDMDVILNIPVEEPL 361
>gi|20141809|sp|Q9NZ72|STMN3_HUMAN Stathmin 3 (SCG10-like protein) Length = 180 Score = 32.0 bits (71), Expect = 0.15 Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 ++ D EE+ ++L E + E + +LAE R E + + +++N AEEK Sbjct: 76 KKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEK 135 Query: 136 YSQK----EDIYEEEIKILTDKLKEAETRAEFTER 166 + K ++I E + L ++L+E E A R Sbjct: 136 LNYKMELSKEIREAHLAALRERLREKELHAAEVRR 170
>gi|135123|sp|P12081|SYH_HUMAN Histidyl-tRNA synthetase (Histidine--tRNA ligase) (HisRS) Length = 509 Score = 32.0 bits (71), Expect = 0.15 Identities = 18/64 (28%), Positives = 34/64 (53%) Query: 87 VPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEE 146 V R I+E LE EE+ E++ Q +L+++ LK +S+ + + E +Y++ Sbjct: 386 VERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVSELWDAGIKAELLYKKN 445 Query: 147 IKIL 150 K+L Sbjct: 446 PKLL 449
>gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP-E protein) Length = 2663 Score = 32.0 bits (71), Expect = 0.15 Identities = 31/155 (20%), Positives = 71/155 (45%), Gaps = 17/155 (10%) Query: 66 KEIQLKEAKHIAEEADR-KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 +++ +K+ + E + K + RK + L+ E + +R QE+ E+I++M + Sbjct: 1533 EQLNIKQISEVQENVNELKQFKEHRKAK--DSALQSIESKMLELTNRLQESQEEIQIMIK 1590 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE---------TRAEFTERLVAKLEKTT 175 + + +E + D +E K + K+KE++ T T+ + ++E Sbjct: 1591 EKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650 Query: 176 DDLEYKLKCNKE----ENLCTQRMLYQTLLDLNEM 206 + E + K N E EN+ ++L++ L ++ + Sbjct: 1651 EQFETQ-KLNLENIETENIRLTQILHENLEEMRSV 1684
Score = 30.4 bits (67), Expect = 0.43 Identities = 20/73 (27%), Positives = 38/73 (52%), Gaps = 1/73 (1%) Query: 103 ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 ER L E + QE+ E+I+ + + L +E K D +E I+ K++E++++ E Sbjct: 1329 ERLRLNE-KFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQE 1387 Query: 163 FTERLVAKLEKTT 175 + + K +TT Sbjct: 1388 QSLNMKEKDNETT 1400
>gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) Length = 793 Score = 32.0 bits (71), Expect = 0.15 Identities = 26/124 (20%), Positives = 57/124 (45%), Gaps = 3/124 (2%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 + +E + + EE R EE R I E + EER + E + +E+ R+ ++ + Sbjct: 310 EAEERERMREEEKRAAEERQR---IKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 366 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 + + +++E+ + E + +L+E + + T+ K+E+ + K +E+ Sbjct: 367 AEERQRARAEEEEKAKVEEQKRNKQLEEKKRAMQETKIKGEKVEQKIEGKWVNEKKAQED 426 Query: 189 NLCT 192 L T Sbjct: 427 KLQT 430
Score = 29.6 bits (65), Expect = 0.73 Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 3/114 (2%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 K ++ +E + EEADRK E K + E E RAE AE R + ++ + + Sbjct: 577 KVLEEEEQRRKQEEADRKLREEEEKRRLKE---EIERRRAEAAEKRQKMPEDGLSDDKKP 633 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 KC + +E + ++ +A ++ ++LE+ T +E Sbjct: 634 FKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIE 687
>gi|2506128|sp|Q05901|ACHB3_HUMAN Neuronal acetylcholine receptor protein, beta-3 chain precursor Length = 458 Score = 32.0 bits (71), Expect = 0.15 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 5/71 (7%) Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTER---LVAKLEKTTDDLEYKL 182 L C+ D ++YS E EE ++ K+ E + + + ++ LVA LEK D + Y Sbjct: 346 LLCMKDHVDRYSSPEK--EESQPVVKGKVLEKKKQKQLSDGEKVLVAFLEKAADSIRYIS 403 Query: 183 KCNKEENLCTQ 193 + K+E+ +Q Sbjct: 404 RHVKKEHFISQ 414
>gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 32.0 bits (71), Expect = 0.15 Identities = 25/120 (20%), Positives = 54/120 (45%), Gaps = 16/120 (13%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 137 EE DR+ +E + +++I+ L + + S+ ++ L+D +++ Sbjct: 498 EELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQD-------------LNDEKKRVH 544 Query: 138 QKEDI---YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR 194 Q ED +E+ + +KL ++E KLE ++L +L ++E N+ Q+ Sbjct: 545 QLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQK 604
>gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 Length = 1020 Score = 32.0 bits (71), Expect = 0.15 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 15/168 (8%) Query: 14 IQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEA 73 +QVLQ+Q DD + L A ++L I + +A Sbjct: 217 VQVLQKQLDDAKEGEMALLSKHK--EVESELAAARERLQQQASDLVLKA---SHIGMLQA 271 Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAE 133 + +E K E K + E + EERA L S+ Q DE+ + Q L+ Sbjct: 272 TQMTQEVTIKDLE-SEKSRVNERLSQLEEERAFL-RSKTQSLDEEQK--QQILELEKKVN 327 Query: 134 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 E +++ YE E+K L +L+E T +L KT ++L +K Sbjct: 328 EAKRTQQEYYERELKNLQSRLEEEVT------QLNEAHSKTLEELAWK 369
Score = 27.3 bits (59), Expect = 3.6 Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 6/86 (6%) Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 EE+ + +E Q++ +NLK E K + +EI L D ++++E Sbjct: 393 EEQHNKDKLNLEEDKNQLQQELENLK------EVLEDKLNTANQEIGHLQDMVRKSEQGL 446 Query: 162 EFTERLVAKLEKTTDDLEYKLKCNKE 187 E L+A L+ + + L+ +L K+ Sbjct: 447 GSAEGLIASLQDSQERLQNELDLTKD 472
>gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin subfamily B member 1 (Giantin) (Macrogolgin) (Golgi complex-associated protein, 372-kDa) (GCP372) Length = 3259 Score = 31.6 bits (70), Expect = 0.19 Identities = 26/131 (19%), Positives = 60/131 (45%), Gaps = 14/131 (10%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 + + +H+ E ++ +E+ KL E + + TE++ + AE +E E++R Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF------ 1681 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL-----EYKLK 183 A+ K + ++ EE ++ + +T E E L++ ++L EY+ Sbjct: 1682 ---AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETL 1738 Query: 184 CNKEENLCTQR 194 K ++L +++ Sbjct: 1739 SKKFQSLMSEK 1749
Score = 29.3 bits (64), Expect = 0.95 Identities = 26/129 (20%), Positives = 50/129 (38%), Gaps = 11/129 (8%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 130 K + ++ DR +E + ++ EE L E C +Q+R M +++ L Sbjct: 2192 KSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELK 2251 Query: 131 DAEEKYSQKEDIYEEEIK-----------ILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 + + I+E + + L + KE ++ E T L + LE Sbjct: 2252 INISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLE 2311 Query: 180 YKLKCNKEE 188 +LK K++ Sbjct: 2312 SELKSLKDQ 2320
Score = 28.5 bits (62), Expect = 1.6 Identities = 31/139 (22%), Positives = 52/139 (37%), Gaps = 18/139 (12%) Query: 68 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 127 +QL + E +K + RKL E L + +L + +++ +++ Q L+ Sbjct: 238 LQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQ 297 Query: 128 CLSDAEEKYSQKEDIYEEEIKILTDK--LKEAETRAEF----------------TERLVA 169 + + EE KIL +K L+ AE + F + A Sbjct: 298 QMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQA 357 Query: 170 KLEKTTDDLEYKLKCNKEE 188 +LE LE K K EE Sbjct: 358 ELESRYSALEQKHKAEMEE 376
Score = 28.1 bits (61), Expect = 2.1 Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 11/90 (12%) Query: 97 DLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 156 D E + R +L + + +Q +L++ L+ + E KY++ E+ KLKE Sbjct: 2530 DAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEE-----------KLKE 2578 Query: 157 AETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 +E E R L++ DL +++ K Sbjct: 2579 SEEANEDLRRSFNALQEEKQDLSKEIESLK 2608
Score = 28.1 bits (61), Expect = 2.1 Identities = 13/75 (17%), Positives = 40/75 (53%) Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLV 168 + + +E ++ ++ Q+ + +S+ E+ + +E + L KL+ E + TE+ + Sbjct: 1605 QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL 1664 Query: 169 AKLEKTTDDLEYKLK 183 + E+ ++++ K++ Sbjct: 1665 QEAEQEMEEMKEKMR 1679
>gi|13124704|sp|Q14457|BCN1_HUMAN Beclin 1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) Length = 450 Score = 31.6 bits (70), Expect = 0.19 Identities = 24/111 (21%), Positives = 50/111 (45%), Gaps = 19/111 (17%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D +++Q+ E K +A E +R +E LE E+ ++ ++ + +D Sbjct: 176 DSEQLQM-ELKELALEEERLIQE-----------LEDVEKNRKIVAENLEKVQAEAERLD 223 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 Q E +Y ++ ++ + L D+LK E + + + + KL+KT Sbjct: 224 QE-------EAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKT 267
>gi|46397348|sp|Q9UKV3|ACIN_HUMAN Apoptotic chromatin condensation inducer in the nucleus (Acinus) Length = 1341 Score = 31.6 bits (70), Expect = 0.19 Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 18/108 (16%) Query: 71 KEAKHIAEEADRKYEEVPRK-------------LVIIEGDLECTEERAELAESRCQETDE 117 +++ I+EE +E PRK + EG EE + SR + Sbjct: 204 RKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSR----NL 259 Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 ++R D+NLK + EE+ ++ED EEE K +EA EF E Sbjct: 260 RVRA-DRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKE 306
>gi|118685|sp|P11532|DMD_HUMAN Dystrophin Length = 3685 Score = 31.6 bits (70), Expect = 0.19 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 14/135 (10%) Query: 67 EIQLKEAK----HIAEEADRKYEEVP---RKLVIIEGDLECTEERAELAESRCQETDEQI 119 E +LKE H+ ++ + E + K V ++ DL E AE E D + Sbjct: 1128 ETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEYLERDFEY 1187 Query: 120 RLMDQNLKCLSD---AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 + D+ K + + A+E+ QKE ++K+LT+ + +A + K E T Sbjct: 1188 KTPDELQKAVEEMKRAKEEAQQKE----AKVKLLTESVNSVIAQAPPVAQEALKKELETL 1243 Query: 177 DLEYKLKCNKEENLC 191 Y+ C + C Sbjct: 1244 TTNYQWLCTRLNGKC 1258
Score = 26.2 bits (56), Expect = 8.1 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 63 RDMKEIQLKEAKHIAEEAD---------RKYEEVPRKLVIIEGDLECTEERAELAESRCQ 113 +DM E K + + D RK EE+ K +++ ++ + Sbjct: 1814 KDMNEDNEGTVKELLQRGDNLQQRITDERKREEIKIKQQLLQTKHNALKDLRSQRRKKAL 1873 Query: 114 ETDEQI----RLMDQNLKCLSDAEEKY-SQKEDIYEEEIKILTDKLKEAETRAEFTER 166 E Q R D LKCL D E+K S E E +IK + +L++ + R Sbjct: 1874 EISHQWYQYKRQADDLLKCLDDIEKKLASLPEPRDERKIKEIDRELQKKKEELNAVRR 1931
>gi|8134353|sp|O95447|CU13_HUMAN Protein C21orf13 Length = 670 Score = 31.2 bits (69), Expect = 0.25 Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 21/146 (14%) Query: 40 AQERLTTALQKLXXXXXXXXXXXRDMKEIQ-LKEAKHIAEEADRKYEEVPRKLVIIEGDL 98 +QE+ T +KL ++ +Q L E K++AE EE+ KL II + Sbjct: 217 SQEKERTLSRKLRETDSQLLKTKDILQALQKLSEDKNLAER-----EELTHKLSIITTKM 271 Query: 99 ECTEERAELAESR----CQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKL 154 + +++ + E + C+ Q+ + + A + + E+K L KL Sbjct: 272 DANDKKIQSLEKQLRLNCRAFSRQLAIETRKTLAAQTATKTL-------QVEVKHLQQKL 324 Query: 155 KEAETRAE----FTERLVAKLEKTTD 176 KE + E ++ R++ L T D Sbjct: 325 KEKDRELEIKNIYSHRILKNLHDTED 350
>gi|30173128|sp|Q9NQS7|INCE_HUMAN Inner centromere protein Length = 919 Score = 31.2 bits (69), Expect = 0.25 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 6/124 (4%) Query: 78 EEADRKYEEVPRKLVIIEGD-LECTEERAELAESRCQE-----TDEQIRLMDQNLKCLSD 131 EE +R+++E+ +K E + L E LAE R QE EQ R + + Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 709 Query: 132 AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLC 191 +E+ Q+ + E+E + ++L+ E + L + E+ +LE K K +++ L Sbjct: 710 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 769 Query: 192 TQRM 195 +++ Sbjct: 770 ERQL 773
>gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (PLC-beta-1) (Phospholipase C-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 31.2 bits (69), Expect = 0.25 Identities = 27/107 (25%), Positives = 56/107 (52%), Gaps = 11/107 (10%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 + +KEI KE K + ++ D+K +E I E +++++++ E + + I+ + Sbjct: 1055 KKLKEICEKEKKELKKKMDKKRQE-----KITEAK---SKDKSQMEEEKTEMIRSYIQEV 1106 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIK--ILTDKLK-EAETRAEFTER 166 Q +K L +A+ K +K +EI+ IL +K K + E E+ ++ Sbjct: 1107 VQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKPKLQVELEQEYQDK 1153
Score = 27.3 bits (59), Expect = 3.6 Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 3/88 (3%) Query: 106 ELAESRCQETDEQIRLMD-QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA--ETRAE 162 +LA + T + I L D Q + L+ +E+Y ++ E IK+L KL + E + Sbjct: 993 DLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQKLTDVAEECQNN 1052 Query: 163 FTERLVAKLEKTTDDLEYKLKCNKEENL 190 ++L EK +L+ K+ ++E + Sbjct: 1053 QLKKLKEICEKEKKELKKKMDKKRQEKI 1080
>gi|52783441|sp|Q6DKK2|TTCJ_HUMAN Tetratricopeptide repeat protein 19 (TPR repeat protein 19) Length = 380 Score = 31.2 bits (69), Expect = 0.25 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 17/130 (13%) Query: 69 QLKEAKHIAEEADRKYEEV-----PRKLVIIEG-----DLECTEERAELAESRCQETDEQ 118 Q +A+ + E+A + EE+ P+ +V++ D + + A + R + Q Sbjct: 252 QPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATTLDAQGRFDEAYIYMQRASDLARQ 311 Query: 119 IR-----LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 I ++ NL + E+Y+Q ++IY+E +K KLK+ E + +A+L K Sbjct: 312 INHPELHMVLSNLAAVLMHRERYTQAKEIYQEALK--QAKLKKDEISVQHIREELAELSK 369 Query: 174 TTDDLEYKLK 183 + L +K Sbjct: 370 KSRPLTNSVK 379
>gi|20141312|sp|O14529|CUTL2_HUMAN Homeobox protein Cux-2 (Cut-like 2) Length = 1505 Score = 31.2 bits (69), Expect = 0.25 Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 4/68 (5%) Query: 110 SRCQETDEQIRLMDQNLKC----LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 +R E +E+I+++ LK L + KY ++ +E+ ++ L++A RAE + Sbjct: 217 ARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAEAAQ 276 Query: 166 RLVAKLEK 173 R V L + Sbjct: 277 REVESLRE 284
Score = 29.3 bits (64), Expect = 0.95 Identities = 26/121 (21%), Positives = 51/121 (42%), Gaps = 9/121 (7%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGD--LECTEERAELAE----SRCQETDEQIRLMD 123 L++A AE A R+ E + +L + L C + + + C + L Sbjct: 265 LEKANQRAEAAQREVESLREQLASVNSSIRLACCSPQGPSGDKVNFTLCSGPRLEAALAS 324 Query: 124 QN---LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 ++ L+ L D + S +++ E + D ++ ++E E+L KL+ +D E Sbjct: 325 KDREILRLLKDVQHLQSSLQELEEASANQIADLERQLTAKSEAIEKLEEKLQAQSDYEEI 384 Query: 181 K 181 K Sbjct: 385 K 385
>gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein) Length = 731 Score = 30.8 bits (68), Expect = 0.33 Identities = 33/152 (21%), Positives = 61/152 (40%), Gaps = 20/152 (13%) Query: 39 HAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAE-----------------EAD 81 H +E +QKL +DM+ Q+ EA+ E E + Sbjct: 473 HEKEMQREEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELE 532 Query: 82 RKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKED 141 + E + ++ IE DL T+ +SR ++ DE+I+ + L + + S+ E+ Sbjct: 533 TELERLKQEFHYIEEDLYRTK---NTLQSRIKDRDEEIQKLRNQLTNKTLSNSSQSELEN 589 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 + + L K E+ + LV +LE+ Sbjct: 590 RLHQLTETLIQKQTMLESLSTEKNSLVFQLER 621
Score = 26.2 bits (56), Expect = 8.1 Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 9/140 (6%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAE-------SRCQETDEQIRLMDQNL 126 K E + E +L +E + + E LAE R E +Q++L NL Sbjct: 362 KREQESYKQMQSEFAARLNKVEMERQNLAEAITLAERKYSDEKKRVDELQQQVKLYKLNL 421 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 + Y QK + + L + LKE + +E ++L ++ + + Sbjct: 422 ESSKQELIDYKQKATRILQSKEKLINSLKEGSGFEGLDSSTASSME--LEELRHEKEMQR 479 Query: 187 EENLCTQRMLYQTLLDLNEM 206 EE ++Q +L +M Sbjct: 480 EEIQKLMGQIHQLRSELQDM 499
>gi|33112293|sp|O95995|GAS8_HUMAN Growth-arrest-specific protein 8 (Growth arrest-specific 11) Length = 478 Score = 30.8 bits (68), Expect = 0.33 Identities = 29/109 (26%), Positives = 55/109 (50%), Gaps = 8/109 (7%) Query: 64 DMKEIQLKE-AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 DM + Q++E I EE DR+ EE R +E D T E+ + +E ++R Sbjct: 25 DMSKEQVEEHVSRIREELDREREE--RNYFQLERDKIHTFW--EITRRQLEEKKAELRNK 80 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 D+ ++ +AEE++ + +Y++++K L + + T + +V KL Sbjct: 81 DREME---EAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKL 126
>gi|126363|sp|P25391|LMA1_HUMAN Laminin alpha-1 chain precursor (Laminin A chain) Length = 3075 Score = 30.8 bits (68), Expect = 0.33 Identities = 22/122 (18%), Positives = 55/122 (45%), Gaps = 11/122 (9%) Query: 68 IQLKEAKHIAEEADRKYEEVPRKLVIIE-----------GDLECTEERAELAESRCQETD 116 ++LK A+ + + Y++ +L +++ +L+ E AE++ QE++ Sbjct: 1720 LELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESN 1779 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 + +++ NL+ SD + +++++ E I + A + + + + LE D Sbjct: 1780 HLLLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQD 1839 Query: 177 DL 178 L Sbjct: 1840 KL 1841
>gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) Length = 957 Score = 30.8 bits (68), Expect = 0.33 Identities = 22/116 (18%), Positives = 54/116 (46%), Gaps = 6/116 (5%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D K+ ++ + +AE+ ++ + L D E +E + + ++++ Sbjct: 429 DDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVK--- 485 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKI---LTDKLKEAETRAEFTERLVAKLEKTTD 176 + L+ L + Y QK E++ + LTD+L + T T+R +++L++ ++ Sbjct: 486 EVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSN 541
>gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170) Length = 1498 Score = 30.8 bits (68), Expect = 0.33 Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 30/136 (22%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEG--DLECTEERAELAESRCQ------ETDE 117 KE+Q KE H+ ++ + ++ L I EG E + +AELAE+R Q + DE Sbjct: 1221 KELQAKE--HLVQKLQAEADD----LQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDE 1274 Query: 118 QIRLMD------QNLKCLSDAEEK----YSQKEDIYEEEIKILTDKLKEAETRAEFTERL 167 Q+ +NLK D +E+ Q+ D+ E++ + KE E + + + Sbjct: 1275 QLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGR------KELEGLQQLLQNV 1328 Query: 168 VAKLEKTTDDLEYKLK 183 ++LE +DL K Sbjct: 1329 KSELEMAQEDLSMTQK 1344
Score = 30.4 bits (67), Expect = 0.43 Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 6/125 (4%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E QL++ K + D++ E + ++ + + L T+E + SR Q D D+ Sbjct: 695 EQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQ---SREQSLDALQTHYDELQ 751 Query: 127 KCLSDAEEKYSQKED---IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L + + + + +ED + + E IL L+ A++ E +R +LE+ T++ L+ Sbjct: 752 ARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLE 811 Query: 184 CNKEE 188 +EE Sbjct: 812 KLREE 816
Score = 28.9 bits (63), Expect = 1.2 Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 11/98 (11%) Query: 95 EGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY--SQKEDIYEEEI----- 147 E DL + + R +E D Q++ + Q L+ + E++ S KE + ++ Sbjct: 1146 EADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHN 1205 Query: 148 ----KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 K + +L E + + E LV KL+ DDL+ + Sbjct: 1206 RRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIR 1243
>gi|22653684|sp|P83436|COG7_HUMAN Conserved oligomeric Golgi complex component 7 Length = 770 Score = 30.8 bits (68), Expect = 0.33 Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 34/167 (20%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL-------- 121 LKE + +E +K+E+ + + + +++ + R +LA QE D+ L Sbjct: 83 LKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADKWSTLSADIEETF 142 Query: 122 --------------MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL 167 M +L L D + YS+K ++ E +K + L + A FT + Sbjct: 143 KTQDIAVISAKLTGMQNSLMMLVDTPD-YSEK-CVHLEALKNRLEALASPQIVAAFTSQA 200 Query: 168 V----------AKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 204 V ++++ L Y KC+K + L + L Q+ L L+ Sbjct: 201 VDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLSLD 247
>gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 Length = 1539 Score = 30.8 bits (68), Expect = 0.33 Identities = 32/128 (25%), Positives = 58/128 (45%), Gaps = 12/128 (9%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEG-DLECTEERAELAESR--CQETDEQIR 120 +MKE+ ++ AE + YE + L +E + E + AEL + Q+ ++ +R Sbjct: 123 EMKELNERQR---AEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLR 179 Query: 121 --LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE----AETRAEFTERLVAKLEKT 174 L D K +SDA+ + + + E E+K+ KL+E A + E +K Sbjct: 180 DELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKE 239 Query: 175 TDDLEYKL 182 + L +L Sbjct: 240 VESLRMQL 247
Score = 30.4 bits (67), Expect = 0.43 Identities = 21/94 (22%), Positives = 48/94 (51%), Gaps = 6/94 (6%) Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 E + + E+ + ++ I + Q +K ++ E+K ++ + E++IKIL + AET Sbjct: 1336 ETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQ 1395 Query: 162 EFTERLVA------KLEKTTDDLEYKLKCNKEEN 189 L +L+K +L ++++ NK+++ Sbjct: 1396 GLKRELQVLRLANHQLDKEKAELIHQIEANKDQS 1429
Score = 26.9 bits (58), Expect = 4.7 Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 14/115 (12%) Query: 72 EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSD 131 + K + + EE+ RK+ +E LE E +L + + E++ ++ K + Sbjct: 922 QGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPMKEKNAKEELIRWEEGKKWQAK 981 Query: 132 AE---EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 E K +KE E+ LT +L + L AK +K L+ KLK Sbjct: 982 IEGIRNKLKEKEG----EVFTLTKQLNTLKD-------LFAKADKEKLTLQRKLK 1025
>gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) (C-NAP1) (Centrosome protein 250) (Centrosome associated protein CEP250) Length = 2442 Score = 30.8 bits (68), Expect = 0.33 Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 9/115 (7%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 +E +++ + +E +++ E L ++ DL+ + +L + + QE ++ +++ Sbjct: 1433 REEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHL 1492 Query: 126 LKCLSDAEEKYS-QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 + + E+K + Q+E I E E K+ ET+ E + +LEK +E Sbjct: 1493 PMAVQEREQKLTVQREQIRELE--------KDRETQRNVLEHQLLELEKKDQMIE 1539
Score = 29.3 bits (64), Expect = 0.95 Identities = 23/122 (18%), Positives = 49/122 (40%), Gaps = 11/122 (9%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQ--------- 113 +D E QL+ E + +++V+++ L+ E+ EL E Q Sbjct: 1752 KDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRA 1811 Query: 114 --ETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 + D+++ + Q + EE+ +K D + ++ LKE + + +L Sbjct: 1812 LAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRL 1871 Query: 172 EK 173 E+ Sbjct: 1872 EE 1873
Score = 26.9 bits (58), Expect = 4.7 Identities = 20/105 (19%), Positives = 48/105 (45%), Gaps = 9/105 (8%) Query: 99 ECTEERAELAESRCQETDEQIRLMDQNL-------KCLSDAEEKYSQKEDIYEEEIKILT 151 + +E+ EL ++ + E + L+ Q L + L ++ ++ ++ + +++L+ Sbjct: 1403 QALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLS 1462 Query: 152 DKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC--NKEENLCTQR 194 LK+ + + + +LEK LE+ +E+ L QR Sbjct: 1463 LDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQR 1507
Score = 26.6 bits (57), Expect = 6.2 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 21/115 (18%) Query: 69 QLKEAKHIAE----EADRKYEE----VPRKLVIIEGDLECTEERAELAE-SRCQETDEQI 119 QL+EA I E + D +Y+E + + L + +L +ER +L E S Q E + Sbjct: 2014 QLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENM 2073 Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 +EK + ++ EEEI+ L ++E + E+ + +L +T Sbjct: 2074 ------------IQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRET 2116
Score = 26.6 bits (57), Expect = 6.2 Identities = 17/72 (23%), Positives = 30/72 (41%) Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 EE A S + +E++ + + L + E + +E + +LT L E E Sbjct: 1378 EEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1437 Query: 162 EFTERLVAKLEK 173 E + +LEK Sbjct: 1438 ETLRGQIQELEK 1449
>gi|2833265|sp|Q15695|U2R1_HUMAN U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related-protein 1 (U2(RNU2) small nuclear RNA auxillary factor 1-like 1) Length = 479 Score = 30.4 bits (67), Expect = 0.43 Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR--LM 122 ++E QL+E K + E +R +EE + + + +E+ E A+ +E + +++ Sbjct: 58 IEEQQLEEEKLLERERERLHEEWLLREQKAQEEFRIKKEKEEAAKKWLEEQERKLKEQWK 117 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 +Q K + E+K +K++ E K+L + E Sbjct: 118 EQQRKEREEEEQKQQEKKEKEEAVQKMLDQAENDLE 153
Score = 29.3 bits (64), Expect = 0.95 Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 11/101 (10%) Query: 88 PRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEI 147 P+K+ E A E R + E RL D L ++ED + EE Sbjct: 10 PKKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLS--------QEEEEDTFIEEQ 61 Query: 148 KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 ++ +KL E E R E + + +K + E+++K KEE Sbjct: 62 QLEEEKLLERE-RERLHEEWLLREQKAQE--EFRIKKEKEE 99
>gi|20138710|sp|Q9BW19|KFC1_HUMAN Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET) Length = 673 Score = 30.4 bits (67), Expect = 0.43 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 7/97 (7%) Query: 90 KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEE-------KYSQKEDI 142 +L + +L+ ER + + Q+ +Q+R Q +K L K + + Sbjct: 142 QLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQ 201 Query: 143 YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 ++E+K L + E E R E LV +L+K +L+ Sbjct: 202 GQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQ 238
>gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing extension spike protein) Length = 577 Score = 30.4 bits (67), Expect = 0.43 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 6/108 (5%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q +E KH + E +K + E + E E E R ++ +EQ + Q L Sbjct: 308 QAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQEL-- 365 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 EE+ + ++ +E + ++ K A+ R E E A L+ + D Sbjct: 366 ----EEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRD 409
Score = 26.6 bits (57), Expect = 6.2 Identities = 27/140 (19%), Positives = 63/140 (45%), Gaps = 13/140 (9%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D E+Q +A+ E+ ++ E LE +++ E+AE ++ + + + Sbjct: 298 DTIEVQQMKAQAREEKHQKQMERAM---------LENEKKKREMAEKEKEKIEREKEELM 348 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 + LK + + +K Q+ + L + K A++ AE +L + ++ + E L+ Sbjct: 349 ERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAE---KLAKERQEAEEAKEALLQ 405 Query: 184 CNKEENLCTQRMLYQTLLDL 203 ++++ TQ L + +L Sbjct: 406 ASRDQKK-TQEQLALEMAEL 424
>gi|417031|sp|P32455|GBP1_HUMAN Interferon-induced guanylate-binding protein 1 (GTP-binding protein 1) (Guanine nucleotide-binding protein 1) (HuGBP-1) Length = 592 Score = 30.4 bits (67), Expect = 0.43 Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 29/147 (19%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL----------- 126 ++ +KY E PRK + E L+ + E +TD+ + ++ + Sbjct: 441 QDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQ 500 Query: 127 ---KCLSDAEEK----YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 K L + + K QKE Y+E +K LT+K++ +L+ + E+T Sbjct: 501 ASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV------QLLKEQERT----- 549 Query: 180 YKLKCNKEENLCTQRMLYQTLLDLNEM 206 LK ++E L + ++ + NE+ Sbjct: 550 LALKLQEQEQLLKEGFQKESRIMKNEI 576
>gi|37077728|sp|Q96HY6|CTB6_HUMAN Protein C20orf116 precursor Length = 314 Score = 30.4 bits (67), Expect = 0.43 Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 7/103 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R ++E Q ++A+ AEEA+R EE R E + + EER L E + +E + + R Sbjct: 123 RKLEEKQARKAQREAEEAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREE 180 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 + E+Y + ++ + E + + + + E ++++ TE Sbjct: 181 QAQRE-----HEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
>gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) Length = 1742 Score = 30.4 bits (67), Expect = 0.43 Identities = 32/137 (23%), Positives = 59/137 (43%), Gaps = 21/137 (15%) Query: 64 DMKEIQLKEA---------KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQE 114 D+++IQ EA ++ E+ R + V KL ++ E + E + + QE Sbjct: 922 DVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQE 981 Query: 115 TDEQIR-LMDQNLKCLSD-----------AEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 E+++ MD K L D E+ + K YE++I+ L +++K + Sbjct: 982 KTEELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKM 1041 Query: 163 FTERLVAKLEKTTDDLE 179 + LV T+D L+ Sbjct: 1042 QLQHLVEGEHVTSDGLK 1058
Score = 30.0 bits (66), Expect = 0.56 Identities = 29/135 (21%), Positives = 57/135 (42%), Gaps = 11/135 (8%) Query: 66 KEIQLKEA------KHIAE---EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETD 116 KEI+L +A KH+ E K E+ ++L + D+E R + + D Sbjct: 1076 KEIELLQAQKIDVEKHVQSQKREMREKMSEITKQL-LESYDIEDVRSRLSVEDLEHLNED 1134 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKE-DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTT 175 ++ + LK + E + Q + D YE+EI+ L K+ ++L + Sbjct: 1135 GELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDIN 1194 Query: 176 DDLEYKLKCNKEENL 190 + + +++ EN+ Sbjct: 1195 ESIRHEVTRLTSENM 1209
Score = 27.3 bits (59), Expect = 3.6 Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 9/91 (9%) Query: 104 RAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEF 163 + +++E Q+ D +IRL +Q K EE +Q EEE + E + Sbjct: 1215 KQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKE 1274 Query: 164 TERLVAKLEKTTD---------DLEYKLKCN 185 E+L+ K+++ + + E ++KCN Sbjct: 1275 KEKLIDKIQEMQEASDHLKKQFETESEVKCN 1305
>gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1 protein) Length = 976 Score = 30.4 bits (67), Expect = 0.43 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Query: 67 EIQLK-EAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 E QL+ E +++ EE +K +EV KL + +EE + + ++ I + Q Sbjct: 569 ETQLRNELEYVREELKQKRDEVKCKL-------DKSEENCNNLRKQVENKNKYIEELQQE 621 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR-AEFTERLVAKLE 172 K L S++ ++YE ++ L +L+ A+ + E T+ ++E Sbjct: 622 NKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIE 669
>gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) Length = 2090 Score = 30.4 bits (67), Expect = 0.43 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 14/142 (9%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL--MDQ 124 E++L++ K +E RK +E LV + L E+ EL + D QI M Q Sbjct: 1453 ELELEKTK--LQELTRKLKERVTILVKQKDVLSHGEKEEEL---KAMMHDLQITCSEMQQ 1507 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC 184 ++ L EK Q+ I EI L ++ + + + L + +++ K + Sbjct: 1508 KVELLRYESEKLQQENSILRNEITTLNEEDSISNLK-------LGTLNGSQEEMWQKTET 1560 Query: 185 NKEENLCTQRMLYQTLLDLNEM 206 K+EN Q+M+ ++E+ Sbjct: 1561 VKQENAAVQKMVENLKKQISEL 1582
>gi|47605963|sp|O75116|ROCK2_HUMAN Rho-associated protein kinase 2 (Rho-associated, coiled-coil containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2) Length = 1388 Score = 30.4 bits (67), Expect = 0.43 Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 12/129 (9%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS 130 +E I + + +E+ +KL +E L + E E +C+ + ++ K Sbjct: 429 RENDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLE------KTAK 482 Query: 131 DAEEKYSQKEDI------YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC 184 + EE+ + ++ + E E +L K E + +A+ LE + L+ +L+ Sbjct: 483 ELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLED 542 Query: 185 NKEENLCTQ 193 K+ N +Q Sbjct: 543 LKKRNQNSQ 551
Score = 26.6 bits (57), Expect = 6.2 Identities = 30/137 (21%), Positives = 59/137 (43%), Gaps = 14/137 (10%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK- 127 QLK + E+ + +++ +L D E E A+S + E+ L ++ LK Sbjct: 693 QLKVIQQSLEQEEAEHKATKARLA----DKNKIYESIEEAKSEAMKEMEKKLLEERTLKQ 748 Query: 128 ----CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK 183 L +AE++ S + ++ + + + LK+ + E L K+E+ T + + Sbjct: 749 KVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQET-----QKR 803 Query: 184 CNKEENLCTQRMLYQTL 200 C + +L Q TL Sbjct: 804 CLTQNDLKMQTQQVNTL 820
>gi|6166575|sp|P37275|TCF8_HUMAN Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2) Length = 1124 Score = 30.0 bits (66), Expect = 0.56 Identities = 16/61 (26%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 101 TEERAELAESRCQETDEQIRLMDQNLKCLSDA--EEKYSQKEDIYEEEIKILTDKLKEAE 158 T E E +E +E D+++ + + +C EE+ ++E++ EEE++ ++ +EA+ Sbjct: 1029 TREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAK 1088 Query: 159 T 159 T Sbjct: 1089 T 1089
>gi|47606000|sp|Q15276|RAP1_HUMAN Rab GTPase binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) Length = 862 Score = 30.0 bits (66), Expect = 0.56 Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 3/77 (3%) Query: 111 RCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAK 170 R E E+ L ++ K DAE+ S + E+EI L DKL EAE + + E +K Sbjct: 160 RLSEGQEEENLENEMKKAQEDAEKLRSVVMPM-EKEIAALKDKLTEAEDKIKELE--ASK 216 Query: 171 LEKTTDDLEYKLKCNKE 187 +++ LE + C + Sbjct: 217 VKELNHYLEAEKSCRTD 233
Score = 27.7 bits (60), Expect = 2.8 Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 13/131 (9%) Query: 77 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 A+ ++ EE+ + L + D++ E+ A L +SR Q ++E +RL N + K+ Sbjct: 603 AQASEILLEELQQGLSQAKRDVQ--EQMAVLMQSREQVSEELVRLQKDN----DSLQGKH 656 Query: 137 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCN----KEE---N 189 S + + E IL D + + + D +E KLK KE+ Sbjct: 657 SLHVSLQQAEDFILPDTTEALRELVLKYREDIINVRTAADHVEEKLKAEILFLKEQIQAE 716 Query: 190 LCTQRMLYQTL 200 C + L +TL Sbjct: 717 QCLKENLEETL 727
>gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 (Lymphocyte-oriented kinase) Length = 968 Score = 30.0 bits (66), Expect = 0.56 Identities = 41/231 (17%), Positives = 84/231 (36%), Gaps = 36/231 (15%) Query: 8 EEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKE 67 +E+ K + + ++ DHA R A +++ ++ + Sbjct: 600 QEINAKKKFFDTELENLERQQKQQVEKMEQDHAVRRREEA-RRIRLEQDRDYTRFQEQLK 658 Query: 68 IQLKEAKHIAEEADR---------KYEEVPRKLVIIEGDLECTE-ERAELAESRCQETDE 117 + KE K+ E+ R K EE +K +++ D + E ELA R TD Sbjct: 659 LMKKEVKNEVEKLPRQQRKESMKQKMEEHTQKKQLLDRDFVAKQKEDLELAMKRLT-TDN 717 Query: 118 QIRLMDQNLKCLSDAEE------------------------KYSQKEDIYEEEIKILTDK 153 + + D+ +CL +E K K+ + + ++L Sbjct: 718 RREICDKERECLMKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKH 777 Query: 154 LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLDLN 204 KE E + +R++ +L+ + +L + T+ +Y+ L +N Sbjct: 778 EKEREQMQRYNQRMIEQLKVRQQQEKARLPKIQRSEGKTRMAMYKKSLHIN 828
>gi|59797953|sp|Q8N1N0|CLE13_HUMAN C-type lectin superfamily member 13 (C-type lectin 13) Length = 539 Score = 30.0 bits (66), Expect = 0.56 Identities = 20/98 (20%), Positives = 45/98 (45%), Gaps = 3/98 (3%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD---QNLKCLSDAEEKYSQKED 141 E ++ +++ DL+ + + A R +TD QI++ +N+ L+ + + Sbjct: 325 ERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMK 384 Query: 142 IYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 EI+ L +K A T+ L + L+K + +++ Sbjct: 385 NASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQ 422
>gi|34098676|sp|Q96G01|BCD1_HUMAN Cytoskeleton-like bicaudal D protein homolog 1 Length = 975 Score = 30.0 bits (66), Expect = 0.56 Identities = 33/182 (18%), Positives = 75/182 (41%), Gaps = 6/182 (3%) Query: 11 KCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKEIQL 70 K K Q++Q + + +H + LT +++ R ++ + Sbjct: 328 KLKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAM-RGLQSSKE 386 Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM----DQNL 126 +A+ E+ EE V I G LE E + +A + + +I+ + ++++ Sbjct: 387 LKAELDGEKGRDSGEEAHDYEVDING-LEILECKYRVAVTEVIDLKAEIKALKEKYNKSV 445 Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 + +D + KY K +Y+E++ L KE+ + E+ + K+ ++ L + Sbjct: 446 ENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQ 505 Query: 187 EE 188 +E Sbjct: 506 DE 507
>gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-associated protein expressed in ventricle 1 (CDV-1 protein) Length = 676 Score = 29.6 bits (65), Expect = 0.73 Identities = 24/129 (18%), Positives = 59/129 (45%), Gaps = 11/129 (8%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 ++ E++ + ++E + Y V K + ++ + + + QE DE+ D Sbjct: 474 EVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYD 533 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE----KTTDDLE 179 C + E S+ E+E++ L ++ + E+R +T ++ LE + TD+++ Sbjct: 534 S---CAAGLESNRSK----LEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK 586 Query: 180 YKLKCNKEE 188 + +++E Sbjct: 587 AYISSDQQE 595
>gi|55976224|sp|O94972|TM37_HUMAN Tripartite motif protein 37 (Mulibrey nanism protein) Length = 964 Score = 29.6 bits (65), Expect = 0.73 Identities = 24/118 (20%), Positives = 52/118 (44%), Gaps = 6/118 (5%) Query: 63 RDMKEIQLKEAKHIAEEADRKYE-EVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL 121 R+ K+ +++E ++ E + + ++ KL+ + G + EL ES QE + Q+R Sbjct: 172 RNAKDERVREIRNAVEMMIARLDTQLKNKLITLMGQKTSLTQETELLESLLQEVEHQLRS 231 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 ++ + +S + E + ++ + + +FT LV + T LE Sbjct: 232 CSKS-ELISKSSEILMMFQQVHRKPMA----SFVTTPVPPDFTSELVPSYDSATFVLE 284
>gi|1710032|sp|P29375|RBB2_HUMAN Retinoblastoma-binding protein 2 (RBBP-2) Length = 1722 Score = 29.6 bits (65), Expect = 0.73 Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 4/45 (8%) Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 L DAE++ + D++ + L D +KEAET A + L++K +K Sbjct: 767 LEDAEDRKYPENDLFRK----LRDAVKEAETCASVAQLLLSKKQK 807
>gi|2497520|sp|Q12840|KINN_HUMAN Neuronal kinesin heavy chain (NKHC) (Kinesin heavy chain isoform 5A) (Kinesin heavy chain neuron-specific 1) Length = 1032 Score = 29.6 bits (65), Expect = 0.73 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 8/94 (8%) Query: 103 ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 E A L C+ET ++ N + + QK YEEEI+ L +L + + Sbjct: 385 EEAALGAELCEETP-----VNDNSSIVVRIAPEERQK---YEEEIRRLYKQLDDKDDEIN 436 Query: 163 FTERLVAKLEKTTDDLEYKLKCNKEENLCTQRML 196 +L+ KL++ D E L + +N QR L Sbjct: 437 QQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
>gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal D protein homolog 2 Length = 824 Score = 29.6 bits (65), Expect = 0.73 Identities = 34/166 (20%), Positives = 69/166 (41%), Gaps = 11/166 (6%) Query: 11 KCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXXRDMKEIQL 70 K K Q++Q + + +H + L+ +K+ ++ +Q Sbjct: 347 KLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSA----LRRLQA 402 Query: 71 KEAKHIA--EEADR-KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLK 127 + + A E DR +E+ V I G E + +A + E EQ++ + + Sbjct: 403 SKERQTALDNEKDRDSHEDGDYYEVDINGP-EILACKYHVAVAEAGELREQLKALRSTHE 461 Query: 128 CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEK 173 E ++++++ YE E + LT+K+ E + L+A+LEK Sbjct: 462 A---REAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEK 504
>gi|55583998|sp|Q9NUQ3|TAXG_HUMAN Gamma-taxilin (Lipopolysaccharide specific response protein 5) Length = 528 Score = 29.6 bits (65), Expect = 0.73 Identities = 24/131 (18%), Positives = 60/131 (45%), Gaps = 11/131 (8%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN----- 125 +E + E+ + E+ + I+ + E + +L +++ Q+T + I+ D+ Sbjct: 267 QENIELGEKLKKLIEQYALREEHIDKVFKRKELQQQLVDAKLQQTTQLIKEADEKHQRER 326 Query: 126 ---LKCLSDAEEKYSQ---KEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 LK +++ KY Q +E ++++ + DK +E +T + L + + + Sbjct: 327 EFLLKEATESRHKYEQMKQQEVQLKQQLSLYMDKFEEFQTTMAKSNELFTTFRQEMEKMT 386 Query: 180 YKLKCNKEENL 190 K+K ++E + Sbjct: 387 KKIKKLEKETI 397
Score = 29.3 bits (64), Expect = 0.95 Identities = 30/162 (18%), Positives = 68/162 (41%), Gaps = 18/162 (11%) Query: 41 QERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLEC 100 Q+ + LQ+ + +E LKEA E+ KYE++ ++ V ++ L Sbjct: 301 QQLVDAKLQQTTQLIKEADEKHQREREFLLKEAT----ESRHKYEQMKQQEVQLKQQLSL 356 Query: 101 TEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE--------------EE 146 ++ E ++ +++E Q ++ ++ +K ++ I+ EE Sbjct: 357 YMDKFEEFQTTMAKSNELFTTFRQEMEKMTKKIKKLEKETIIWRTKWENNNKALLQMAEE 416 Query: 147 IKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 + + K + + E E+L L+ ++L K++ KE+ Sbjct: 417 KTVRDKEYKALQIKLERLEKLCRALQTERNELNEKVEVLKEQ 458
>gi|38258174|sp|Q8N8D1|PCD7_HUMAN Programmed cell death protein 7 (ES18) (HES18) Length = 485 Score = 29.6 bits (65), Expect = 0.73 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 10/100 (10%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 129 L +A ++ E A R+ E V R+ + + E E +R E +++I +KC+ Sbjct: 226 LTQAAYVGE-ARRRLERVRRRRLRLRERAREREAEREAEAARAVEREQEIDRW--RVKCV 282 Query: 130 SDAEEKYSQKEDIYEEEIKILTD-KLKEAETRAEFTERLV 168 + EEK E+E+K D L E + T+R+V Sbjct: 283 QEVEEKKR------EQELKAAADGVLSEVRKKQADTKRMV 316
>gi|12643822|sp|Q9NYC9|DYH9_HUMAN Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9) Length = 4486 Score = 29.6 bits (65), Expect = 0.73 Identities = 21/101 (20%), Positives = 47/101 (46%), Gaps = 13/101 (12%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAES----------RC 112 +D+ +++ ++H+ EEA+ + V + + + G L +E + + C Sbjct: 576 KDLDAVRMIYSQHVQEEAELGFSPVHKNMPTVAGGLRWAQELRQRIQGPFSNFGRITHPC 635 Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 E+ E R M Q + + EKY + +YE+ + +++K Sbjct: 636 MESAEGKR-MQQKYEDMLSLLEKYETR--LYEDWCRTVSEK 673
>gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin) Length = 8797 Score = 29.6 bits (65), Expect = 0.73 Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 5/82 (6%) Query: 77 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 ++E D + E + KL + + CTE+ ++ +ET+E +++ L+ L DA + Sbjct: 5576 SKEIDSELEAMTEKLQYLTS-VYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDM 5634 Query: 137 SQKEDIYEEEIKILTDKLKEAE 158 + +E E+K L L++A+ Sbjct: 5635 KK----FEAELKKLQAALEQAQ 5652
Score = 28.5 bits (62), Expect = 1.6 Identities = 28/156 (17%), Positives = 67/156 (42%), Gaps = 22/156 (14%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVII--------------EGDLECTEERAELAESRCQE 114 +++++K ++E R+ +++ + L I + D + E + S+ E Sbjct: 5419 EVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLME 5478 Query: 115 TDEQI-RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA-------EFTER 166 D + + ++QN + +K + +++++ I+ ++L + A E E Sbjct: 5479 LDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLEL 5538 Query: 167 LVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 202 ++ +EK + N L Q +L+QTLL+ Sbjct: 5539 ILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLE 5574
Score = 26.6 bits (57), Expect = 6.2 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 19/116 (16%) Query: 75 HIAEEADRKYEEVPRKLVIIEGDLECTEERAE---LAESRCQETDEQIRLMDQNLKCLSD 131 +I + A +YE+ +++ ++ +E E +A S QE QI Sbjct: 5731 NIMQAAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQI-----------S 5779 Query: 132 AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL-----VAKLEKTTDDLEYKL 182 E+ +QK Y+E+I L K K +A+ L V L + T+DL+ +L Sbjct: 5780 RHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGEL 5835
>gi|33860183|sp|Q9UM54|MYO6_HUMAN Myosin VI Length = 1285 Score = 29.3 bits (64), Expect = 0.95 Identities = 26/112 (23%), Positives = 52/112 (46%), Gaps = 3/112 (2%) Query: 77 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 A + ++ EE +L I+ ++E +R E E R ++ +E+ R+ + EE+ Sbjct: 912 ALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEER 971 Query: 137 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 ++ED +E +I + + + E + A LE+ D E L+ + E Sbjct: 972 KKRED---DEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSE 1020
>gi|60390643|sp|Q9BZI7|REN3B_HUMAN Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (hUpf3p-X) Length = 483 Score = 29.3 bits (64), Expect = 0.95 Identities = 29/112 (25%), Positives = 50/112 (44%), Gaps = 16/112 (14%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R E++ ++ K +E+ R Y E R + E +ER R + +E+ R Sbjct: 324 RSDSELKDEKPKRPEDESGRDYRERER-------EYERDQERILRERERLKRQEEERRRQ 376 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 + + E+ + +KE EE+K D L++ +AE TE + EKT Sbjct: 377 KERY----EKEKTFKRKE----EEMKKEKDTLRDKGKKAESTES-IGSSEKT 419
>gi|14424221|sp|O75154|EFER_HUMAN Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin) Length = 756 Score = 29.3 bits (64), Expect = 0.95 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 18/109 (16%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAE-----SRCQETDEQI 119 +KE +L+ + + EE R+ E L C ER + E +R Q+ DE+ Sbjct: 508 LKEQELRACEMVLEETRRQKE------------LLCKMEREKSIEIENLQTRLQQLDEEN 555 Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKL-KEAETRAEFTERL 167 + CL E+ +++ +EI+ LT +L +E E + +RL Sbjct: 556 SELRSCTPCLKANIERLEEEKQKLLDEIESLTLRLSEEQENKRRMGDRL 604
>gi|19857096|sp|P21817|RYR1_HUMAN Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel) Length = 5038 Score = 29.3 bits (64), Expect = 0.95 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 16/114 (14%) Query: 85 EEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE 144 E+V + L +IE ++ EE E E +E DE+ + D+ EE +KED + Sbjct: 1857 EDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDE--------EETAQEKEDEEK 1908 Query: 145 EEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQ 198 EE ++ E E E L+ K + ++ ++ C+ E C Q + ++ Sbjct: 1909 EE-----EEAAEGEKEEGLEEGLLQM--KLPESVKLQM-CHLLEYFCDQELQHR 1954
>gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L) Length = 544 Score = 29.3 bits (64), Expect = 0.95 Identities = 25/115 (21%), Positives = 55/115 (47%), Gaps = 13/115 (11%) Query: 90 KLVIIEGDLEC--TEERAELAE---------SRCQETDEQIRLMDQNLKCLSDAEEKYSQ 138 ++ I DL+ T+E+A+L + R E ++Q ++++ L L + S+ Sbjct: 74 QVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSR 133 Query: 139 KEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQ 193 +YE+EI+ L ++A T + + L + E+ ++ L+ EE + ++ Sbjct: 134 FRALYEQEIRDLRLAAEDATTNEK--QALRGEREEGLEETLRNLQARYEEEVLSR 186
>gi|20141591|sp|Q15811|ITN1_HUMAN Intersectin 1 (SH3 domain-containing protein 1A) (SH3P17) Length = 1721 Score = 29.3 bits (64), Expect = 0.95 Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 7/126 (5%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 QL+ A+ +E +R+ +E R+L + E LE E E ++ E+ + L+ Sbjct: 385 QLERAEQERKERERQEQERKRQLEL-EKQLEKQRELERQREEERRKEIERREAAKRELER 443 Query: 129 LSDAEEKYSQKEDIY------EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 E + ++++++ +E+I +L K K E E +LE D+ +L Sbjct: 444 QRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRL 503 Query: 183 KCNKEE 188 ++E Sbjct: 504 TTQRQE 509
>gi|55977767|sp|P08670|VIME_HUMAN Vimentin Length = 466 Score = 28.9 bits (63), Expect = 1.2 Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 13/135 (9%) Query: 63 RDMKEIQLKEAK-HIAEEADR-KYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR 120 R ++++L+E A D+ ++ E K+++ E + + ++ L + +E E R Sbjct: 100 RTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRR 159 Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD---- 176 +DQ L++ + + + D E+I L +KL+E + E E + + D Sbjct: 160 QVDQ----LTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAENTLQSFRQDVDNASL 215 Query: 177 ---DLEYKLKCNKEE 188 DLE K++ +EE Sbjct: 216 ARLDLERKVESLQEE 230
>gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like protein B3) (RB3) Length = 189 Score = 28.9 bits (63), Expect = 1.2 Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 81 DRKYEEVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQ 138 D EE+ +KL E + E LAE R E + + +++N + A+EK +Q Sbjct: 88 DPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQ 147 Query: 139 K----EDIYEEEIKILTDKLKEAETRAE 162 K ++ E + + ++L+E + AE Sbjct: 148 KMESNKENREAHLAAMLERLQEKDKHAE 175
>gi|37999715|sp|Q8ND90|PMA1_HUMAN Paraneoplastic antigen Ma1 (Neuron- and testis-specific protein 1) (37 kDa neuronal protein) Length = 353 Score = 28.9 bits (63), Expect = 1.2 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 92 VIIEGDLECTEERAELAESRCQETDEQIRLMDQN------LKCLSDAEEKYSQKEDIYEE 145 V+ E + E+R L ES + IR++ N +CL E+ + E + Sbjct: 187 VLEEWQVSDVEKRRRLMESLRGPAADVIRILKSNNPAITTAECLKALEQVFGSVESSRDA 246 Query: 146 EIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 +IK L E + + RL L+K + Sbjct: 247 QIKFLNTYQNPGEKLSAYVIRLEPLLQKVVE 277
>gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain) Length = 3110 Score = 28.9 bits (63), Expect = 1.2 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 8/118 (6%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R+++ +Q KE + +E RK E ++ I E +L E + + E+ + M Sbjct: 1712 RNLEGLQ-KEIDQMIKELRRKNLETQKE--IAEDELVAAEALLKKVKKLFGESRGENEEM 1768 Query: 123 DQNLK-CLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 +++L+ L+D + K D+ E TDK++EA ++ + LEK + +E Sbjct: 1769 EKDLREKLADYKNKVDDAWDLLREA----TDKIREANRLFAVNQKNMTALEKKKEAVE 1822
>gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) Length = 1382 Score = 28.9 bits (63), Expect = 1.2 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 11/92 (11%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKC 128 Q KE + I +++ EE R + + +ER E + + +E++R + +K Sbjct: 797 QRKEERRITYYREKEEEEQRR------AEEQMLKEREERERAERAKREEELREYQERVKK 850 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETR 160 L + E K Q+E EE ++ +E E R Sbjct: 851 LEEVERKKRQRELEIEER-----ERRREEERR 877
Score = 26.9 bits (58), Expect = 4.7 Identities = 23/113 (20%), Positives = 51/113 (45%), Gaps = 17/113 (15%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 + +E +L++ + EE R+ + K I++ E ++ + +E EQI+ + Sbjct: 595 EQREAELQKVRKAEEERLRQEAKEREKERILQ-------EHEQIKKKTVRERLEQIKKTE 647 Query: 124 QNLKCLSDAEEK----------YSQKEDIYEEEIKILTDKLKEAETRAEFTER 166 K D + + +++ + E+E K L ++LK E + ++ ER Sbjct: 648 LGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFER 700
>gi|18202737|sp|Q9BXS4|CA08_HUMAN Protein C1orf8 precursor (Liver membrane-bound protein) (HSPC001) (UNQ169/PRO195) Length = 323 Score = 28.9 bits (63), Expect = 1.2 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 1/62 (1%) Query: 110 SRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVA 169 S CQ D+ I L L+C S E YSQ ++ Y + ++L AE R E L+ Sbjct: 78 SICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLG-CQNQLPFAELRQEQLMSLMP 136 Query: 170 KL 171 K+ Sbjct: 137 KM 138
>gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crosslinking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin 1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620) Length = 5430 Score = 28.9 bits (63), Expect = 1.2 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 + L Q++K +SDA + ++E + EEE + +K+KE + L + Sbjct: 1396 VTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKEL---LGWVSTLARNTQGKATSS 1452 Query: 179 EYKLKCNKEENLCTQRMLYQTLLDLNE 205 E K + E+ + Q++L + L E Sbjct: 1453 ETKESTDIEKAILEQQVLSEELTTKKE 1479
>gi|13431428|sp|Q9Y2W7|CSEN_HUMAN Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3) Length = 256 Score = 28.5 bits (62), Expect = 1.6 Identities = 21/85 (24%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL-- 178 L D N EE + + IY+ + L+E + AE ER K+++ D + Sbjct: 173 LYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILRE-DAPAEHVERFFEKMDRNQDGVVT 231 Query: 179 --EYKLKCNKEENLCTQRMLYQTLL 201 E+ C K+EN+ + L++ ++ Sbjct: 232 IEEFLEACQKDENIMSSMQLFENVI 256
>gi|12231058|sp|Q14320|XAP5_HUMAN XAP-5 protein (HXC-26 protein) Length = 339 Score = 28.5 bits (62), Expect = 1.6 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 7/101 (6%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE----QIRL 121 KE+Q+K K E +RK +E RK+ + LE EE E E +E +I Sbjct: 95 KELQMKLEK--LREKERK-KEAKRKISSLSFTLEEEEEGGEEEEEAAMYEEEMEREEITT 151 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 + L D + + D EEE ++ + +E E + E Sbjct: 152 KKRKLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAKQE 192
>gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1) Length = 775 Score = 28.5 bits (62), Expect = 1.6 Identities = 33/152 (21%), Positives = 67/152 (44%), Gaps = 10/152 (6%) Query: 38 DHAQERLTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGD 97 + A+++ A+QKL D++ L A D EE + +++ Sbjct: 381 EKAKQKDQLAIQKLKERILQL-----DLENKTLALAASSRSPLDSHGEESSLDVNVLKDK 435 Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 +E + ++A + Q T + +L D + S+A + Y++E+K +LKE Sbjct: 436 MEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEKATALYYQQELK----QLKEE 491 Query: 158 ETRAEFTERLVAKLEKTTD-DLEYKLKCNKEE 188 R + ++V K + T D +L +L+ +E+ Sbjct: 492 FERYKMRAQVVLKSKNTKDGNLGKELEAAQEQ 523
>gi|57012596|sp|Q86UF2|CAG6_HUMAN Protein cTAGE-6 (cTAGE family member 6) Length = 732 Score = 28.5 bits (62), Expect = 1.6 Identities = 16/55 (29%), Positives = 28/55 (50%) Query: 134 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 EK ++ E+EI L LKE +++ + L+A + K+ LE + K K + Sbjct: 88 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 142
>gi|24418846|sp|O60296|A2S3_HUMAN Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 3 Length = 914 Score = 28.5 bits (62), Expect = 1.6 Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 18/101 (17%) Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKIL------TDKLKEAETRAE 162 +++ Q T E L D+N++CL E +EEIK L T L +++ Sbjct: 317 DAQRQLTMELHELQDRNMECLGMLHES--------QEEIKELRSRSGPTAHLYFSQSYGA 368 Query: 163 FT-ERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLLD 202 FT E L A++E T + KL ++E +L Q+ + + D Sbjct: 369 FTGESLAAEIEGT---MRKKLSLDEESSLFKQKAQQKRVFD 406
>gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes 4-like 1 protein (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) Length = 1288 Score = 28.5 bits (62), Expect = 1.6 Identities = 32/149 (21%), Positives = 62/149 (41%), Gaps = 18/149 (12%) Query: 76 IAEEADRKYEEVPR-----------KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 +AE+A + EV R KL + L+ ++ + S + I+ D+ Sbjct: 873 VAEKAGKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADR 932 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA-------EFTERLVAKLEKTTDD 177 NL+ D+ + ++ E+E+ LT +LK E +A E + +++K + Sbjct: 933 NLQKAQDSVLRTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRN 992 Query: 178 LEYKLKCNKEENLCTQRMLYQTLLDLNEM 206 L +LK +E Q+ L L ++ Sbjct: 993 LLQELKVIQENEHALQKDALSIKLKLEQI 1021
>gi|60390647|sp|Q9HAU5|RENT2_HUMAN Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2) Length = 1272 Score = 28.5 bits (62), Expect = 1.6 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 13/104 (12%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE-------QIRLMDQNLKCLS 130 EE+ R+ +++ R+ +I G + + + + E E DE + N ++ Sbjct: 994 EESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVN 1053 Query: 131 DAEEKY------SQKEDIYEEEIKILTDKLKEAETRAEFTERLV 168 + EE+ + E+ EE LTD KE ET E TE ++ Sbjct: 1054 EPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMI 1097
>gi|18202743|sp|Q9BZ01|FRGL_HUMAN Hypothetical FRG1-like protein c20orf80 Length = 182 Score = 28.5 bits (62), Expect = 1.6 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 25/110 (22%) Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 + C E A+S+ +E I++ S AE++ +K+DI EE+ +K+ Sbjct: 89 IRCNEAGDIEAKSKTAGEEEMIKIR-------SCAEKETKKKDDIPEED----KGNVKQC 137 Query: 158 ETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR-----MLYQTLLD 202 E + ++K ++KLK +KEE+ ++ L++TLLD Sbjct: 138 E---------INYVKKFQSFQDHKLKISKEESKILKKAQKDGFLHETLLD 178
>gi|46577708|sp|Q9P2H5|UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 (Ubiquitin thiolesterase 35) (Ubiquitin-specific processing protease 35) (Deubiquitinating enzyme 35) Length = 1017 Score = 28.5 bits (62), Expect = 1.6 Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 2/67 (2%) Query: 96 GDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLK 155 G EER E E +E E+ + ++ + E + ++E++ EEE K+ + K Sbjct: 667 GGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGERE--KEEEVEEEEEKVEKETEK 724 Query: 156 EAETRAE 162 EAE E Sbjct: 725 EAEQEKE 731
>gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein) Length = 693 Score = 28.5 bits (62), Expect = 1.6 Identities = 34/135 (25%), Positives = 51/135 (37%), Gaps = 21/135 (15%) Query: 74 KHIAEEADRKYEEV---------------PRKLVIIEGDLECTEERAELAESRCQETDEQ 118 + + +EA +EV L+ E E+ L E Q EQ Sbjct: 298 EQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQ 357 Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 RL +QN + + Q E + ++E +L++ E R E + K EK D Sbjct: 358 ERLCEQNERLREQQKTLQEQGERLRKQE-----QRLRKQEERLRKEEERLQKQEKRLWDQ 412 Query: 179 EYKLKCNKEENLCTQ 193 E +L KEE L Q Sbjct: 413 EERL-WKKEERLQKQ 426
>gi|25453064|sp|Q9UPT6|JIP3_HUMAN C-jun-amino-terminal kinase interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3) Length = 1334 Score = 28.5 bits (62), Expect = 1.6 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 8/87 (9%) Query: 113 QETDEQIRLMDQNLKCLS-DAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 +E +EQ+ + K L AEEK+ + ED E+E K L +++ E + T +L K Sbjct: 87 REDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKKELQIQVEHYEFQ---TRQLELKA 143 Query: 172 EKTTDDL----EYKLKCNKEENLCTQR 194 + D + E + + KE N QR Sbjct: 144 KNYADQISRLEERESEMKKEYNALHQR 170
>gi|57015281|sp|O15320|CAG5_HUMAN Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11) (MEA6/MEA11) Length = 804 Score = 28.5 bits (62), Expect = 1.6 Identities = 16/55 (29%), Positives = 28/55 (50%) Query: 134 EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 EK ++ E+EI L +LKE +++ + L+A + K LE + K K + Sbjct: 132 EKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQ 186
>gi|6831571|sp|Q13325|IFT5_HUMAN Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein) Length = 482 Score = 28.1 bits (61), Expect = 2.1 Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 14/70 (20%) Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILT-----------DKLKEAETRAEFTERLVAKLEKT 174 L+CL AEE Q+ EE ++T D+L+EA+ ++T ++ +K Sbjct: 71 LECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQ---KYTGKIGNVCKKL 127 Query: 175 TDDLEYKLKC 184 + YKL+C Sbjct: 128 SSPSNYKLEC 137
>gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Villin 2) Length = 586 Score = 28.1 bits (61), Expect = 2.1 Identities = 27/106 (25%), Positives = 47/106 (44%), Gaps = 12/106 (11%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMD 123 D E+Q +A+ E+ ++ E LE ++R E E +E ++ +R + Sbjct: 298 DTIEVQQMKAQAREEKHQKQLERQ---------QLETEKKRRETVE---REKEQMMREKE 345 Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVA 169 + + L D EEK + E E+I+ +E + E ERL A Sbjct: 346 ELMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEA 391
>gi|24212088|sp|O94906|PRPU_HUMAN U5 snRNP-associated 102 kDa protein (U5-102 kDa protein) Length = 941 Score = 28.1 bits (61), Expect = 2.1 Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 70 LKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCL 129 ++ A+ + EEA R YE+ P KL +++G +E +E E A + ++ L Sbjct: 691 IRAAQDLCEEALRHYEDFP-KLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLL 749 Query: 130 SDAEEKYSQ 138 S EEK Q Sbjct: 750 SRLEEKIGQ 758
>gi|6093491|sp|O96000|NIDM_HUMAN NADH-ubiquinone oxidoreductase PDSW subunit (Complex I-PDSW) (CI-PDSW) Length = 172 Score = 28.1 bits (61), Expect = 2.1 Identities = 12/55 (21%), Positives = 32/55 (58%), Gaps = 2/55 (3%) Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETR--AEFTERLVAKLEKTT 175 ++++ C+ +AE ++ + + +E I I+ D+LK + R + + + ++E+ T Sbjct: 73 EEDIMCMYEAEMQWKRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFT 127
Score = 28.1 bits (61), Expect = 2.1 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 2/80 (2%) Query: 68 IQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQI-RLMDQNL 126 I+ + AK+ R+Y VP E D+ C E AE+ R + D++I +M L Sbjct: 46 IERQHAKNRYYYYHRQYRRVPDITECKEEDIMCMYE-AEMQWKRDYKVDQEIINIMQDRL 104 Query: 127 KCLSDAEEKYSQKEDIYEEE 146 K E + Q+ I E E Sbjct: 105 KACQQREGQNYQQNCIKEVE 124
>gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW-11) Length = 1583 Score = 28.1 bits (61), Expect = 2.1 Identities = 21/112 (18%), Positives = 57/112 (50%), Gaps = 3/112 (2%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE-ERAELA--ESRCQETDEQIRLMDQN 125 +L+E + ++ ++ ++ ++L +++ D + T E+A E +E ++++ + Sbjct: 1022 ELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNK 1081 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 ++ L + QK++ +EEI L +++ E + ++L+ K +K D Sbjct: 1082 IEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1133
Score = 28.1 bits (61), Expect = 2.1 Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 42/197 (21%) Query: 39 HAQERLTTALQKLXXXXXXXXXXXRD-MKEIQLKEAKHIAEEADRKYEEVPRKLVI---- 93 H Q+ + + ++L ++ M +I+ +H AE K E+ LV Sbjct: 128 HYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEI--NKLNELKENLVKQCEA 185 Query: 94 ----IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKI 149 I+ EC E A S + ++ ++ Q + E + E++K Sbjct: 186 SEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFV----------EQVVNEKVKH 235 Query: 150 LTDKLKEAETR-------AEFTERLVAKLEKTT-----------DDLEYK---LKCNKEE 188 L D LKE E++ + L KLE +DLE+K L KEE Sbjct: 236 LEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEE 295 Query: 189 NLCTQRMLYQTLLDLNE 205 C L L LN+ Sbjct: 296 QGCVIEKLKSELAGLNK 312
Score = 27.3 bits (59), Expect = 3.6 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 102 EERAELAESRCQETDE---QIRLMDQNLKCLSDAEEKYSQ--KEDI--YEEEIKILTDKL 154 EE+ E E C+E +E +I+L+ K D+ K +Q KE++ E L+ + Sbjct: 849 EEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASM 908 Query: 155 KEAETRAEFTERLVAKLEKTTDDLE 179 ++ AE + L+ + EK ++ L+ Sbjct: 909 RDLIQGAESYKNLLLEYEKQSEQLD 933
Score = 27.3 bits (59), Expect = 3.6 Identities = 22/116 (18%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 137 E+ + E+ +K+ + G LE T + + + + ++ Q++++ ++ + LS + Sbjct: 531 EQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLS------A 584 Query: 138 QKEDIYEEEIKILTDK---LKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 + + +YEE K+ ++K ++ E E ++ K T + + +L +++NL Sbjct: 585 EVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNL 640
Score = 26.2 bits (56), Expect = 8.1 Identities = 26/113 (23%), Positives = 50/113 (44%), Gaps = 7/113 (6%) Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 L+ +ERA E R ++ Q+R + ++ E + + + K+L ++ E Sbjct: 932 LDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEV 991 Query: 158 E-TRAEFTERLVA-KLEKTTDDLEYKLKCNKEENLCTQ-----RMLYQTLLDL 203 + +A + L A KL+K E+ N+ E L Q + L +T+ +L Sbjct: 992 QRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQEL 1044
>gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein C20orf23 (Sorting nexin 23) Length = 1317 Score = 28.1 bits (61), Expect = 2.1 Identities = 30/131 (22%), Positives = 53/131 (40%), Gaps = 10/131 (7%) Query: 67 EIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNL 126 E Q +E E + EE+ K + +LE ++ E + QIR +++L Sbjct: 599 ERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESL 658 Query: 127 KCLSD----------AEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTD 176 K S AE++ ++E + E++ L K +E ET E L E + Sbjct: 659 KRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNN 718 Query: 177 DLEYKLKCNKE 187 + K + +E Sbjct: 719 EKAEKFQIFQE 729
>gi|17366990|sp|Q9NRI5|DIS1_HUMAN Disrupted in schizophrenia 1 protein Length = 854 Score = 28.1 bits (61), Expect = 2.1 Identities = 14/39 (35%), Positives = 22/39 (56%) Query: 144 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKL 182 +E IK L LKE T+ +E+ + L K +D+E +L Sbjct: 547 QERIKSLNLSLKEITTKVCMSEKFCSTLRKKVNDIETQL 585
>gi|1717869|sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (Ubiquitin thiolesterase 5) (Ubiquitin-specific processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T) Length = 858 Score = 27.7 bits (60), Expect = 2.8 Identities = 17/64 (26%), Positives = 34/64 (53%), Gaps = 5/64 (7%) Query: 107 LAESRCQETD---EQIR-LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 + E C+ ++ E R L+++ +KCL+ + KY+Q+ D Y ++ + D E E Sbjct: 446 MVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD-YIMQLPVPMDAALNKEELLE 504 Query: 163 FTER 166 + E+ Sbjct: 505 YEEK 508
>gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting protein 1 related (Hip1-related) (Hip 12) Length = 1068 Score = 27.7 bits (60), Expect = 2.8 Identities = 29/138 (21%), Positives = 63/138 (45%), Gaps = 7/138 (5%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 +KE + + + E++ K EE +L ++ +LE + ELA ++ E + +Q Sbjct: 488 VKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEA--KAGELARAQ-----EALSHTEQ 540 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKC 184 + LS + S ++D ++ L A++ TE +++ ++ + + +L+ Sbjct: 541 SKSELSSRLDTLSAEKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQEQGELQG 600 Query: 185 NKEENLCTQRMLYQTLLD 202 E ++ L Q LLD Sbjct: 601 RLAERESQEQGLRQRLLD 618
>gi|135846|sp|P20962|PTMS_HUMAN Parathymosin Length = 102 Score = 27.7 bits (60), Expect = 2.8 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 9/93 (9%) Query: 73 AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDA 132 AK + E+ ++ E+ RK E E EE AE +ET E D+ + Sbjct: 14 AKDLKEKKEKVEEKASRK----ERKKEVVEEEENGAEEEEEETAEDGEEEDE-----GEE 64 Query: 133 EEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 E++ ++ED +K ++ EA+ + + TE Sbjct: 65 EDEEEEEEDDEGPALKRAAEEEDEADPKRQKTE 97
>gi|55976584|sp|Q9BYJ4|TM34_HUMAN Tripartite motif protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21) Length = 488 Score = 27.7 bits (60), Expect = 2.8 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 8/103 (7%) Query: 74 KHIAEEADRKYEEVPRKLVIIEGDLECTEE--RAELAESRCQETDEQIRLM---DQNLKC 128 + + +E K + V ++L E + E E R E + Q E+ R+ DQ Sbjct: 134 EEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSI 193 Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 L++ E++ Q+ EEE K DK EAE ++LV +L Sbjct: 194 LNNEEQRELQR---LEEEEKKTLDKFAEAEDELVQQKQLVREL 233
>gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 Length = 957 Score = 27.7 bits (60), Expect = 2.8 Identities = 28/139 (20%), Positives = 63/139 (45%), Gaps = 10/139 (7%) Query: 66 KEIQLKEAKHIAEEADRKYEEVP---RKLVIIE--GDLECTEERAELAESRCQETDEQIR 120 ++++ K+ + EE R+ + + + L I E LE T + + ++R T + + Sbjct: 772 QQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLA 831 Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 + +L L E+ Q E+I E + + L + E + E +K +KT +++ Sbjct: 832 EKEAHLANLRI--ERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEV-- 887 Query: 181 KLKCNKEENLCTQRMLYQT 199 + +E++ ++ QT Sbjct: 888 -MALKREKDRLVHQLKQQT 905
Score = 27.7 bits (60), Expect = 2.8 Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 7/117 (5%) Query: 71 KEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAE-LAESRCQETDEQIRLMDQNLKCL 129 K+ + +E+ +K E+ + + LE ER +AE+ Q + ++ ++DQ K Sbjct: 295 KQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEV-ILDQKEKEN 353 Query: 130 SDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 E+ ++ + E K K +T E + +A LE+ DLE +++ K Sbjct: 354 IHLREELHRRSQLQPEPAKT-----KALQTVIEMKDTKIASLERNIRDLEDEIQMLK 405
>gi|13431957|sp|O60763|VDP_HUMAN General vesicular transport factor p115 (Transcytosis associated protein) (TAP) (Vesicle docking protein) Length = 962 Score = 27.7 bits (60), Expect = 2.8 Identities = 30/150 (20%), Positives = 68/150 (45%), Gaps = 37/150 (24%) Query: 65 MKEIQ--LKEAKHIAEEADRKYEEVPRKL------------VIIEGDLECTEERAELAES 110 +KE++ + +A + + E D+K EEV + L +I E DL+ E R +++ Sbjct: 617 VKELEGVITKAIYKSSEEDKKEEEVKKTLEQHDNIVTHYKNMIREQDLQLEELRQQVSTL 676 Query: 111 RCQETDEQIR-LMDQNLKCLSDAEEKY--------------------SQKEDIYEEEIKI 149 +CQ +EQ++ + Q + + +++Y +Q I EEI Sbjct: 677 KCQ--NEQLQTAVTQQVSQIQQHKDQYNLLKIQLGKDNQHQGSYSEGAQMNGIQPEEIGR 734 Query: 150 LTDKLKEAETRAEFTERLVAKLEKTTDDLE 179 L ++++E + E + + + + ++++ Sbjct: 735 LREEIEELKRNQELLQSQLTEKDSMIENMK 764
>gi|23831158|sp|P54257|HAP1_HUMAN Huntingtin-associated protein 1 (HAP-1) (Neuroan 1) Length = 671 Score = 27.7 bits (60), Expect = 2.8 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 17/81 (20%) Query: 118 QIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 Q+ L D+ L+ SD++E+ +E+ EE KEAE E E+ +D Sbjct: 245 QVNLRDELLQLYSDSDEEDEDEEEEEEE---------KEAEEEQE--------EEEAEED 287 Query: 178 LEYKLKCNKEENLCTQRMLYQ 198 L+ C+ + + + +L+Q Sbjct: 288 LQCAHPCDAPKLISQEALLHQ 308
>gi|32469766|sp|Q92805|GOA1_HUMAN Golgi autoantigen, golgin subfamily A member 1 (Golgin-97) Length = 767 Score = 27.7 bits (60), Expect = 2.8 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 6/84 (7%) Query: 84 YEEVPRKLVIIEGDLECTEERAELAESR-CQETDE-----QIRLMDQNLKCLSDAEEKYS 137 Y E R L I+ LE E+ + + R QE +E + ++ + L+ ++++S Sbjct: 77 YAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWS 136 Query: 138 QKEDIYEEEIKILTDKLKEAETRA 161 +K D E+E ILT +L+E + ++ Sbjct: 137 EKMDQLEKEKNILTAQLQEMKNQS 160
Score = 27.3 bits (59), Expect = 3.6 Identities = 32/178 (17%), Positives = 71/178 (39%), Gaps = 20/178 (11%) Query: 44 LTTALQKLXXXXXXXXXXXRDMKEIQ------LKEAKHIAEEADRKYEEVPRKLVIIEGD 97 LT LQ++ +M E++ L + KH+ + + ++ ++L + Sbjct: 149 LTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRE 208 Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSD-----------AEEKYS---QKEDIY 143 L T+E + + +++ + ++ L + AE K + QKE Sbjct: 209 LSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQEL 268 Query: 144 EEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQRMLYQTLL 201 + I+ L+ L++ + E ++ L++ LE +L+ N Q +L + L Sbjct: 269 QALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTL 326
>gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) Length = 2567 Score = 27.7 bits (60), Expect = 2.8 Identities = 17/98 (17%), Positives = 52/98 (53%), Gaps = 10/98 (10%) Query: 90 KLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKI 149 K + + +LE + E +E++C+E + +++ +L+ + E ++ + + +E++ Sbjct: 1825 KTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYR 1884 Query: 150 LTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 L + ++A+ L+ ++++ DDL ++ +K+ Sbjct: 1885 L--QFEKAD--------LLKRIDEDQDDLNELMQKHKD 1912
Score = 27.3 bits (59), Expect = 3.6 Identities = 33/153 (21%), Positives = 64/153 (41%), Gaps = 36/153 (23%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTE----------------------ERAE 106 +L++ E+++ K EE + ++ DLE E+A+ Sbjct: 1832 ELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKAD 1891 Query: 107 LAESRCQETDEQIRLMD-------QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAET 159 L + ++ D+ LM Q+ + +E Q E+ +E+ K L ++L+ A+ Sbjct: 1892 LLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHK-LQEQLQVAQM 1950 Query: 160 RAEFTER------LVAKLEKTTDDLEYKLKCNK 186 R E+ E+ +V++ E DLE K + K Sbjct: 1951 RIEYLEQSTVDRAIVSRQEAVICDLENKTEFQK 1983
>gi|12644018|sp|P55196|AFAD_HUMAN Afadin (AF-6 protein) Length = 1816 Score = 27.7 bits (60), Expect = 2.8 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 17/96 (17%) Query: 77 AEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 AE R +E R+ +E E R AE R ++ +E+ R ++ K DAEEK Sbjct: 1582 AERRARLQDEERRRQQQLE------EMRKREAEDRARQEEERRRQEEERTK--RDAEEKR 1633 Query: 137 SQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLE 172 Q+E Y EAE R + E LE Sbjct: 1634 RQEEGYYSR---------LEAERRRQHDEAARRLLE 1660
>gi|119360|sp|P14625|ENPL_HUMAN Endoplasmin precursor (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1) Length = 803 Score = 27.3 bits (59), Expect = 3.6 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 25/118 (21%) Query: 94 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEK------------------ 135 +E DL + E + + Q +E I+L N + + EK Sbjct: 31 VEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLII 90 Query: 136 ---YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 Y KE E I +D L + + E ++ E+ T K+KC+KE+NL Sbjct: 91 NSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELT----VKIKCDKEKNL 144
>gi|547748|sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal 9 (Cytokeratin 9) (K9) (CK 9) Length = 622 Score = 27.3 bits (59), Expect = 3.6 Identities = 24/131 (18%), Positives = 60/131 (45%), Gaps = 12/131 (9%) Query: 79 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN--LKCLSDAEEKY 136 + + +YE + +L+ ++ + + EE ++L + + +I + K L+D ++Y Sbjct: 272 DLEMQYETLQEELMALKKNHK--EEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEY 329 Query: 137 SQ-----KEDI---YEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 Q ++DI YE +I + ++ + + + + V +L +LE +L+ + Sbjct: 330 EQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSK 389 Query: 189 NLCTQRMLYQT 199 ++ L T Sbjct: 390 KAALEKSLEDT 400
>gi|14194715|sp|Q92817|EVPL_HUMAN Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein) Length = 2033 Score = 27.3 bits (59), Expect = 3.6 Identities = 29/144 (20%), Positives = 61/144 (42%), Gaps = 26/144 (18%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQE-TDEQIRL 121 R+ K +Q++ + ++A + + + ++++ ++ D +ERA + E +E T Q R Sbjct: 1497 RECKNLQVQI--DVLQKAKSQEKTIYKEVIRVQKDRVLEDERARVWEMLNRERTARQAR- 1553 Query: 122 MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 EEE + L +++ AET R ++L++ D + + Sbjct: 1554 ----------------------EEEARRLRERIDRAETLGRTWSREESELQRARDQADQE 1591 Query: 182 LKCNKEENLCTQRMLYQTLLDLNE 205 ++E +R Q L L E Sbjct: 1592 CGRLQQELRALERQKQQQTLQLQE 1615
>gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3) Length = 916 Score = 27.3 bits (59), Expect = 3.6 Identities = 16/84 (19%), Positives = 37/84 (44%) Query: 94 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 IE +++ ++ D++IR + L+ ++ + + D EE+I L ++ Sbjct: 129 IEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKER 188 Query: 154 LKEAETRAEFTERLVAKLEKTTDD 177 +E + TE + L K ++ Sbjct: 189 FEEEARLRDDTEAAIRALRKDIEE 212
>gi|8928460|sp|O75962|TRIO_HUMAN Triple functional domain protein (PTPRF interacting protein) Length = 3038 Score = 27.3 bits (59), Expect = 3.6 Identities = 27/123 (21%), Positives = 55/123 (44%), Gaps = 12/123 (9%) Query: 73 AKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR----LMDQNLKC 128 A++ AD+ E + E D E + A E R Q+ ++ L+D ++ Sbjct: 558 AQNTYTNADKLLEAAEQLAQTGECDPEEIYQAAHQLEDRIQDFVRRVEQRKILLDMSVSF 617 Query: 129 LSDAEEKYS-----QKE---DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 + +E ++ QKE D+Y E ++ + D +K + + T ++ + K +DL Sbjct: 618 HTHVKELWTWLEELQKELLDDVYAESVEAVQDLIKRFGQQQQTTLQVTVNVIKEGEDLIQ 677 Query: 181 KLK 183 +L+ Sbjct: 678 QLR 680
>gi|50403775|sp|Q14149|ZCW3_HUMAN Zinc finger CW-type coiled-coil domain protein 3 Length = 939 Score = 27.3 bits (59), Expect = 3.6 Identities = 18/96 (18%), Positives = 48/96 (50%), Gaps = 8/96 (8%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDE---QIR 120 ++ + +K+ + + +E D V VI+ +E + E E+ + D+ Q++ Sbjct: 643 EVPSLVVKKEETVEDEID-----VRNDAVILPSCVEAEAKIHETQETTDKSADDAGCQLQ 697 Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKE 156 + L +++ +E Y ++ ++ ++IK+L ++ E Sbjct: 698 ELRNQLLLVTEEKENYKRQCHMFTDQIKVLQQRILE 733
>gi|13638422|sp|Q01538|MYT1_HUMAN Myelin transcription factor 1 (MYT1) (MYTI) (Proteolipid protein binding protein) (PLPB1) Length = 1121 Score = 26.9 bits (58), Expect = 4.7 Identities = 20/90 (22%), Positives = 44/90 (48%), Gaps = 6/90 (6%) Query: 98 LECTEERAE------LAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILT 151 +E T ER++ L ++ +E+ +Q ++ + + EE+ ++ED EEE + Sbjct: 225 VEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284 Query: 152 DKLKEAETRAEFTERLVAKLEKTTDDLEYK 181 ++ +E E E E + E+ D+ ++ Sbjct: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQ 314
>gi|18202499|sp|Q14331|FRG1_HUMAN FRG1 protein (FSHD region gene 1 protein) Length = 258 Score = 26.9 bits (58), Expect = 4.7 Identities = 27/110 (24%), Positives = 51/110 (46%), Gaps = 25/110 (22%) Query: 98 LECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA 157 + C E A+S+ +E I++ S AE + +K+DI EE+ +K+ Sbjct: 157 IRCNEAGDIEAKSKTAGEEEMIKIR-------SCAERETKKKDDIPEED----KGNVKQC 205 Query: 158 ETRAEFTERLVAKLEKTTDDLEYKLKCNKEENLCTQR-----MLYQTLLD 202 E + ++K ++KLK +KE++ ++ L++TLLD Sbjct: 206 E---------INYVKKFQSFQDHKLKISKEDSKILKKARKDGFLHETLLD 246
>gi|21759000|sp|Q12955|ANK3_HUMAN Ankyrin 3 (ANK-3) (Ankyrin G) Length = 4377 Score = 26.9 bits (58), Expect = 4.7 Identities = 13/53 (24%), Positives = 28/53 (52%) Query: 109 ESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 E R E++ D+ + + +AEEK ++ + ++ + L D+L+ E +A Sbjct: 2561 EDRLDRGREKLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLNDELQSPEKKA 2613
>gi|38372394|sp|Q9NUV9|GIM4_HUMAN GTPase, IMAP family member 4 (Immunity-associated protein 4) (Immunity-associated nucleotide 1 protein) (hIAN1) (MSTP062) Length = 329 Score = 26.9 bits (58), Expect = 4.7 Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 4/58 (6%) Query: 113 QETDEQIRLMDQNLKCLSDAE---EKYSQKEDIYEEEIKILTDKLKEAETRAEFTERL 167 Q +E+I+ Q ++ L E EK +E+ YEE+I+ L DK+++ + + + ++L Sbjct: 227 QRAEEEIQKQTQAMQELHRVELEREKARIREE-YEEKIRKLEDKVEQEKRKKQMEKKL 283
>gi|21431832|sp|O75683|SUR6_HUMAN Surfeit locus protein 6 Length = 361 Score = 26.9 bits (58), Expect = 4.7 Identities = 44/190 (23%), Positives = 67/190 (35%), Gaps = 32/190 (16%) Query: 3 GIATMEEVKCKIQVLQQQADDXXXXXXXXXXXXXXDHAQERLTTALQKLXXXXXXXXXXX 62 G+AT E + VL+Q+ + A+E AL+K Sbjct: 103 GLATEPESVFALDVLRQRLHEKIQEARGQGS------AKELSPAALEKRRRRKQERDRKK 156 Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R KE++ KE AEEA E V E T E A C E E L+ Sbjct: 157 RKRKELRAKEKARKAEEATEAQEVV-----------EATPEGA------CTEPREPPGLI 199 Query: 123 DQNLKCLSDAEEKYSQKEDIYEEEIK----ILTDK-----LKEAETRAEFTERLVAKLEK 173 ++ D +Q+ + +K LT + L+ + R + L + E Sbjct: 200 FNKVEVSEDEPASKAQRRKEKRQRVKGNLTPLTGRNYRQLLERLQARQSRLDELRGQDEG 259 Query: 174 TTDDLEYKLK 183 +LE K+K Sbjct: 260 KAQELEAKMK 269
>gi|9297020|sp|Q13402|MYO7A_HUMAN Myosin VIIa Length = 2215 Score = 26.9 bits (58), Expect = 4.7 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR 120 KE+ K+AK EEA+RK++E +L + + E E+ A + E E+ R Sbjct: 882 KEMSAKKAK---EEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERAR 933
>gi|55976597|sp|Q9H8W5|TM45_HUMAN Tripartite motif protein 45 (RING finger protein 99) Length = 580 Score = 26.9 bits (58), Expect = 4.7 Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 13/80 (16%) Query: 127 KCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNK 186 K L E+ +QKE+ + + L L + T EFTE L+ + DLE Sbjct: 294 KLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLT----SGSDLEI------ 343 Query: 187 EENLCTQRMLYQTLLDLNEM 206 L T+R++ + L LN++ Sbjct: 344 ---LITKRVVVERLRKLNKV 360
>gi|56748851|sp|Q96MT8|CE63_HUMAN Centrosomal protein of 63 kDa (Cep63 protein) Length = 703 Score = 26.9 bits (58), Expect = 4.7 Identities = 29/145 (20%), Positives = 61/145 (42%), Gaps = 32/145 (22%) Query: 93 IIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLS------------------DAEE 134 +++ ++ C E E + C++ +++ + LK + E+ Sbjct: 345 LLQAEVTCLEGSLESVSATCKQLSQELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQ 404 Query: 135 KYSQKEDIYEEEIKILTDKLKEAE--------TRAEFTERLVAKLEKTTDD-LEYK---- 181 YS + + EI LT +L + + + ++ +RL A+++K D +E+K Sbjct: 405 SYSSALEGMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILD 464 Query: 182 -LKCNKEENLCTQRMLYQTLLDLNE 205 L+ K EN M+ + L L+E Sbjct: 465 QLESLKLENRHLSEMVMKLELGLHE 489
>gi|45477011|sp|O75113|N4B1_HUMAN Nedd4-binding protein 1 (N4BP1) Length = 943 Score = 26.9 bits (58), Expect = 4.7 Identities = 16/65 (24%), Positives = 36/65 (55%), Gaps = 9/65 (13%) Query: 130 SDAEEKYSQK----EDIYEEEI-----KILTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 SD+EE++++K E++ E EI + + + + + +E L +++TT+++EY Sbjct: 335 SDSEERHTKKQFSLENVQEGEILHDAKTLAGNVIADLSDSSADSENLSPDIKETTEEMEY 394 Query: 181 KLKCN 185 + N Sbjct: 395 NILVN 399
>gi|20137932|sp|Q9BXL6|CARE_HUMAN Caspase recruitment domain protein 14 (CARD-containing MAGUK protein 2) (Carma 2) Length = 1004 Score = 26.9 bits (58), Expect = 4.7 Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 66 KEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN 125 KE+ + + EE +E+ R ++ +LE E+ A + +E RL ++N Sbjct: 212 KELAASRCRSLQEELYLLKQELQRANMVSSCELELQEQSLRTASDQESGDEELNRLKEEN 271 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE-TRAEFTERLVAKLEK 173 K L ++K+ IL L EA +R E ER+ + E+ Sbjct: 272 EK-LRSLTFSLAEKD--------ILEQSLDEARGSRQELVERIHSLRER 311
Score = 26.2 bits (56), Expect = 8.1 Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 7/71 (9%) Query: 103 ERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 + ELA SRC+ E++ L+ Q L+ A S + ++ E+ ++ +D+ E+ E Sbjct: 210 QEKELAASRCRSLQEELYLLKQELQ---RANMVSSCELELQEQSLRTASDQ----ESGDE 262 Query: 163 FTERLVAKLEK 173 RL + EK Sbjct: 263 ELNRLKEENEK 273
>gi|20138768|sp|Q9NZM3|ITN2_HUMAN Intersectin 2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP associated protein) Length = 1696 Score = 26.9 bits (58), Expect = 4.7 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 6/60 (10%) Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAE-TRAEFTERLVAKLEKTTDDLEYKLKCNKE 187 L + E Y+ ++ E+ KI DKLKE E R E ++ +K D+ K K KE Sbjct: 646 LKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQK-----KKLEDEAARKAKQGKE 700
>gi|547754|sp|P35908|K22E_HUMAN Keratin, type II cytoskeletal 2 epidermal (Cytokeratin 2e) (K2e) (CK 2e) Length = 645 Score = 26.9 bits (58), Expect = 4.7 Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 3/74 (4%) Query: 63 RDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 R + +L + + E+ +KYE+ K E D ++ + A E ++ L+ Sbjct: 253 RTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLL 312 Query: 123 DQN---LKCLSDAE 133 +Q LK L DAE Sbjct: 313 NQEIEFLKVLYDAE 326
>gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein) Length = 5262 Score = 26.9 bits (58), Expect = 4.7 Identities = 21/87 (24%), Positives = 39/87 (44%), Gaps = 2/87 (2%) Query: 75 HIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEE 134 H A E D + + + + +GD E E E+ D+ + + +L +D E Sbjct: 2725 HKALEDDEELAHLGLGVDVAKGDDELGT--LENLETNDPHLDDLLNGDEFDLLAYTDPEL 2782 Query: 135 KYSQKEDIYEEEIKILTDKLKEAETRA 161 K+DI+ E ++++ +EAE A Sbjct: 2783 DTGDKKDIFNEHLRLVESANEEAEREA 2809
>gi|20141510|sp|P19013|K2C4_HUMAN Keratin, type II cytoskeletal 4 (Cytokeratin 4) (K4) (CK4) Length = 534 Score = 26.9 bits (58), Expect = 4.7 Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 13/125 (10%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQN--- 125 +LK + E+ KYEE K E D ++ + A E + ++ ++ Sbjct: 226 ELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINF 285 Query: 126 LKCLSDAEEKYSQKEDIYEEEIKILTDKLKE-------AETRAEFTERLVAKLEKTTDDL 178 LK L DAE Q + + + + D + AE RA++ E +A+ K + Sbjct: 286 LKVLYDAELSQMQTH-VSDTSVVLSMDNNRNLDLDSIIAEVRAQYEE--IAQRSKAEAEA 342 Query: 179 EYKLK 183 Y+ K Sbjct: 343 LYQTK 347
>gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentrin B) (Kendrin) Length = 3336 Score = 26.9 bits (58), Expect = 4.7 Identities = 24/113 (21%), Positives = 50/113 (44%), Gaps = 19/113 (16%) Query: 95 EGDLECTEERA--------------ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKE 140 +GDLE ERA L ++ +E E +++ ++NL + + K+ Sbjct: 657 DGDLEADTERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNL--YEKLQHETRLKD 714 Query: 141 DIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD---LEYKLKCNKEENL 190 D+ + + ++ D KE + TE + + ++ D ++ +L+ EE L Sbjct: 715 DLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKL 767
>gi|1706622|sp|P52732|KIF11_HUMAN Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor interacting protein 5) (TRIP5) (Kinesin-like protein 1) Length = 1057 Score = 26.6 bits (57), Expect = 6.2 Identities = 23/118 (19%), Positives = 50/118 (42%), Gaps = 7/118 (5%) Query: 64 DMKEIQLKEAKHIAEEADRKYEEVPRKLV---IIEGDLECTEERAELAESRC----QETD 116 D + L+ E + +E +LV I LE TEE+ A S+ +ET Sbjct: 448 DQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETT 507 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKT 174 + + + L ++ ++ +DI+ + + L + ++E ++ + ++ KT Sbjct: 508 KDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKT 565
>gi|48428133|sp|Q96M83|CCD7_HUMAN Coiled-coil domain containing protein 7 Length = 486 Score = 26.6 bits (57), Expect = 6.2 Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 13/144 (9%) Query: 44 LTTALQKLXXXXXXXXXXXRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEE 103 L LQKL R K ++ + K + D + + P K I+ DL+ ++ Sbjct: 320 LENELQKLKDKEKTKPTNNRTKKAVKTVKKKDKGKSEDSEKKMSPEKEFKIKEDLDQVQK 379 Query: 104 RAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEF 163 A L E + ++ L +Q + L +AE+ Q +E KL ++E + E Sbjct: 380 VARL------EIENKV-LQEQLKQALQEAEKAKHQLNYFLNQE------KLLKSEGKTET 426 Query: 164 TERLVAKLEKTTDDLEYKLKCNKE 187 T ++ K + + KE Sbjct: 427 TMQVGNSQTKVKGEDSKNIPLEKE 450
>gi|6707663|sp|P78363|ABCA4_HUMAN Retinal-specific ATP-binding cassette transporter (ATP-binding cassette, sub-family A, member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein) Length = 2273 Score = 26.6 bits (57), Expect = 6.2 Identities = 12/41 (29%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 115 TDEQIRLMDQNLKCL-SDAEEKYSQKEDIYEEEIKILTDKL 154 TD +RL++Q L+CL D E Y+ + + + + +L + + Sbjct: 506 TDRTLRLVNQYLECLVLDKFESYNDETQLTQRALSLLEENM 546
>gi|20532406|sp|P17980|PRS6A_HUMAN 26S protease regulatory subunit 6A (TAT-binding protein 1) (TBP-1) (Proteasome subunit P50) Length = 439 Score = 26.6 bits (57), Expect = 6.2 Identities = 14/74 (18%), Positives = 36/74 (48%) Query: 106 ELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 E+ + +E ++ RL+D +K + + + + +++IK ++K+K +T Sbjct: 32 EVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVS 91 Query: 166 RLVAKLEKTTDDLE 179 ++ L+ +D E Sbjct: 92 NVIELLDVDPNDQE 105
>gi|57015409|sp|Q8IWT3|PARC_HUMAN p53-associated parkin-like cytoplasmic protein (UbcH7 associated protein 1) Length = 2517 Score = 26.6 bits (57), Expect = 6.2 Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 124 QNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE 165 +N C D EE+ + EEE + L K + +T AE T+ Sbjct: 586 RNHSCTPDPEEESKSEASFSEEETESLKAKAEAPKTEAEPTK 627
>gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) Length = 149 Score = 26.6 bits (57), Expect = 6.2 Identities = 22/91 (24%), Positives = 42/91 (46%), Gaps = 6/91 (6%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERA--ELAESRCQETDEQIRLMDQNLKCLSDAEEK 135 ++ D EE+ +KL E + E +LAE R E + + +++N AEEK Sbjct: 41 KKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEK 100 Query: 136 YSQKEDIYEE----EIKILTDKLKEAETRAE 162 + K + +E ++ ++L+E + E Sbjct: 101 LTHKMEANKENREAQMAAKLERLREKDKHIE 131
>gi|30580600|sp|O00463|TRA5_HUMAN TNF receptor associated factor 5 (RING finger protein 84) Length = 557 Score = 26.6 bits (57), Expect = 6.2 Identities = 16/62 (25%), Positives = 27/62 (43%) Query: 112 CQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 C TD++ L L + +K EE+I L L++ E++ + + KL Sbjct: 229 CAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKL 288 Query: 172 EK 173 EK Sbjct: 289 EK 290
>gi|20138891|sp|O75925|PIAS1_HUMAN Protein inhibitor of activated STAT protein 1 (Gu binding protein) (GBP) (RNA helicase II binding protein) (DEAD/H box-binding protein 1) Length = 651 Score = 26.6 bits (57), Expect = 6.2 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 64 DMKEIQLKEAKHIAEEADRK-YEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLM 122 D EIQ KE A +K +EV ++G L T E + + ++++ ++ Sbjct: 401 DCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVI 460 Query: 123 DQNLKCLSDAEEK 135 D + SD EE+ Sbjct: 461 DLTIDSSSDEEEE 473
>gi|12229723|sp|Q9ULD4|BRF3_HUMAN Bromodomain and PHD finger-containing protein 3 Length = 1214 Score = 26.6 bits (57), Expect = 6.2 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 119 IRLMDQNLKCLSDAEEK-YSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDD 177 IR + +L+ +AE++ +K +EE+K KL+ RA L+ K EK + Sbjct: 529 IRRLHSHLQSQRNAEQREQDEKTSAVKEELKYW-QKLRHDLERARLLIELIRKREKLKRE 587 Query: 178 LEYKLKCNKEENLCTQRMLYQTLLDL 203 + E L +L +T LDL Sbjct: 588 QVKVQQAAMELELMPFNVLLRTTLDL 613
>gi|47606762|sp|Q96MU7|YT521_HUMAN Putative splicing factor YT521 Length = 727 Score = 26.2 bits (56), Expect = 8.1 Identities = 19/72 (26%), Positives = 40/72 (55%), Gaps = 4/72 (5%) Query: 94 IEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDK 153 +E D+E EE E AE +E DE ++ + + EE+ ++E+ YE++ + ++ Sbjct: 205 VEEDVEEDEEVEEDAEED-EEVDEDGEEEEEEEE---EEEEEEEEEEEEYEQDERDQKEE 260 Query: 154 LKEAETRAEFTE 165 + +TR+E ++ Sbjct: 261 GNDYDTRSEASD 272
>gi|7387887|sp|O00566|MPP10_HUMAN U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10) Length = 681 Score = 26.2 bits (56), Expect = 8.1 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 12/89 (13%) Query: 120 RLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL--EKTTDD 177 R+ DQ D K KED YE + ++ D K + AE E+ KL +KT ++ Sbjct: 432 RIRDQ---AWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKLNQQKTAEE 488 Query: 178 LEYKLKCNKEENLCTQRMLYQTLLDLNEM 206 E++ Q+M+ L L+ + Sbjct: 489 -------ENPEHVEIQKMMDSLFLKLDAL 510
>gi|6831676|sp|O15266|SHOX_HUMAN Short stature homeobox protein (Short stature homeobox containing protein) (Pseudoautosomal homeobox containing osteogenic protein) Length = 292 Score = 26.2 bits (56), Expect = 8.1 Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 138 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEE 188 ++ED+ E+ T KLK+ +R FT + +LE+ D+ Y +EE Sbjct: 100 KREDVKSEDEDGQT-KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREE 149
>gi|2500771|sp|Q16181|SEPT7_HUMAN Septin 7 (CDC10 protein homolog) Length = 418 Score = 26.2 bits (56), Expect = 8.1 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 11/115 (9%) Query: 89 RKLVIIE-GDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEI 147 RKL + ++ + + +L +S + +E+ R +K + + E ++E ++ Sbjct: 293 RKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKME------MEMEQVFEMKV 346 Query: 148 KILTDKLKEAETRAEFT-ERLVAKLEKTTDDLEYKLKCNKEENL---CTQRMLYQ 198 K KLK++E + E++ LE +LE K + ++E QR+L Q Sbjct: 347 KEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQ 401
>gi|22653670|sp|Q9UIG0|BAZ1B_HUMAN Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (WBRS9) (Williams syndrome transcription factor) (hWALP2) Length = 1483 Score = 26.2 bits (56), Expect = 8.1 Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 78 EEADRKYEEVPRKLVIIE-GDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKY 136 E DR+ + VI + L +E+RA L E ++ L++ + S +EE Sbjct: 484 ENKDREDKRSALSCVISKTARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEE-- 541 Query: 137 SQKEDIYEEEIKILTDKLKE-AETRAEFTERLVAKLEK 173 Q+++ +++ + L KLKE A+ R E + ++ +LEK Sbjct: 542 -QRKEYLKKKREELKKKLKEKAKERRE--KEMLERLEK 576
>gi|47116932|sp|Q9NQ29|L7L1_HUMAN Putative RNA-binding protein Luc7-like 1 (SR+89) (Putative SR protein LUC7B1) Length = 371 Score = 26.2 bits (56), Expect = 8.1 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 17/79 (21%) Query: 99 ECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYE--EEIKILTDKLKE 156 EC + R ELA+ R ET E+I + E ++ E ++E EEI L K ++ Sbjct: 96 EC-DRRTELAKKRLAETQEEI------------SAEVSAKAEKVHELNEEIGKLLAKAEQ 142 Query: 157 --AETRAEFTERLVAKLEK 173 AE + +++++ ++EK Sbjct: 143 LGAEGNVDESQKILMEVEK 161
>gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 3) (PTPRF-interacting protein alpha 3) Length = 1194 Score = 26.2 bits (56), Expect = 8.1 Identities = 25/152 (16%), Positives = 65/152 (42%), Gaps = 2/152 (1%) Query: 41 QERLTTALQKLXXXXXXXXXX--XRDMKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDL 98 +ER+TT ++ D E +L + + +++ K ++ L + L Sbjct: 302 EERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKL 361 Query: 99 ECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAE 158 + T ++AE + +++ +++ + + EE+ Q E EE+ + L + + Sbjct: 362 QQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREK 421 Query: 159 TRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 + +RL ++K + +L+ + +E + Sbjct: 422 MNDDHNKRLSETVDKLLSESNERLQLHLKERM 453
>gi|125351|sp|P16591|FER_HUMAN Proto-oncogene tyrosine-protein kinase FER (p94-FER) (c-FER) Length = 822 Score = 26.2 bits (56), Expect = 8.1 Identities = 25/138 (18%), Positives = 61/138 (44%), Gaps = 17/138 (12%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQET------DEQIRLMDQNLKCLSD 131 E+A +Y++ KL ++ + A+L +++ + D ++ ++ +K L Sbjct: 165 EKAKERYDKATMKLHMLHNQYVLALKGAQLHQNQYYDITLPLLLDSLQKMQEEMIKALKG 224 Query: 132 AEEKYSQKEDIYEEEI----KILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLK---- 183 ++YSQ + EEI K + +++ + E+ + + +TT E +++ Sbjct: 225 IFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFI--DVHRTTAAKEQEIEFDTS 282 Query: 184 -CNKEENLCTQRMLYQTL 200 + ENL +++ L Sbjct: 283 LLEENENLQANEIMWNNL 300
>gi|21542000|sp|Q16543|CC37_HUMAN Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) Length = 378 Score = 26.2 bits (56), Expect = 8.1 Identities = 40/167 (23%), Positives = 66/167 (39%), Gaps = 42/167 (25%) Query: 79 EADRKYEEVPRKLVIIE----GDLECTEERAELAESRCQETDEQIRL---------MDQN 125 E RK E RKL +E G E +AE + R +E + +L M N Sbjct: 56 ECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWN 115 Query: 126 LKCLS------------------DAEEKYSQKE----DIYEEEIKILTDKLKEAETRAEF 163 + LS D+EE QK + YE++IK + +++ Sbjct: 116 VDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYL 175 Query: 164 TERLVAKLEKTTD-------DLEYKLKCNKEENLCTQRMLYQTLLDL 203 ++ + E+T + DLE + KC E + Q ++ Q +L+L Sbjct: 176 SDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILEL 222
>gi|13626094|sp|Q9UGM1|ACH9_HUMAN Neuronal acetylcholine receptor protein, alpha-9 chain precursor Length = 479 Score = 26.2 bits (56), Expect = 8.1 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 7/86 (8%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQ 124 + E LK A++ ++ RK + R ++ DL C + + AES C + R ++ Sbjct: 377 LPESNLKAARN--KDLSRKKDMNKR----LKNDLGCQGKNPQEAESYCAQYKVLTRNIEY 430 Query: 125 NLKCLSDAEEKYSQKEDIYEEEIKIL 150 KCL D + S K +++ K++ Sbjct: 431 IAKCLKD-HKATSSKGSEWKKVAKVI 455
>gi|6166119|sp|O60879|DIAP2_HUMAN Diaphanous protein homolog 2 (Diaphanous-related formin 2) (DRF2) Length = 1101 Score = 26.2 bits (56), Expect = 8.1 Identities = 23/118 (19%), Positives = 54/118 (45%), Gaps = 9/118 (7%) Query: 63 RDMKEIQLKEA--KHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR 120 RD K K IA+ + KY ++ + +E ++ A++ +S ++QI Sbjct: 865 RDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIV 924 Query: 121 LMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL 178 +++++K K+ Q E+ +++ ++ +T K A + E + + K ++L Sbjct: 925 HLERDIK-------KFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENL 975
>gi|41017271|sp|O60237|MPT2_HUMAN Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase targeting subunit 2) (Myosin phosphatase target subunit 2) Length = 982 Score = 26.2 bits (56), Expect = 8.1 Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 7/69 (10%) Query: 113 QETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEA-------ETRAEFTE 165 +ET + + ++N + S + E+ +++ E E + DK EA E+++ TE Sbjct: 342 EETPKSQEMEEENKESSSSSSEEEEGEDEASESETEKEADKKPEAFVNHSNSESKSSITE 401 Query: 166 RLVAKLEKT 174 ++ A + T Sbjct: 402 QIPAPAQNT 410
>gi|20978544|sp|O00232|PSDC_HUMAN 26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit p55) Length = 456 Score = 26.2 bits (56), Expect = 8.1 Identities = 35/134 (26%), Positives = 55/134 (41%), Gaps = 17/134 (12%) Query: 69 QLKEAKHIAEEADRKYEEVPRKLVIIE------GDLECTEERAELAESRCQET------D 116 +L E +A+E + +EV L+ +E D+ T C E + Sbjct: 27 RLPECAKLAKEG--RLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLN 84 Query: 117 EQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTE-RLVAKLEKTT 175 E I L+ + L A K Q+ Y EEI L KL+ +T TE ++ ++E+ Sbjct: 85 ENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERAR 144 Query: 176 DDLEYKLKCNKEEN 189 L L KE+N Sbjct: 145 --LTKTLATIKEQN 156
>gi|41017595|sp|O95153|RIP1_HUMAN Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor interacting protein) (PBR-IP) (RIM binding protein 1) (RIM-BP1) Length = 1857 Score = 26.2 bits (56), Expect = 8.1 Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 7/109 (6%) Query: 79 EADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIR-LMDQNLKCLSDAEE--- 134 E +++ +++ +L E E+ A + RC+E + Q+R ++N + + + Sbjct: 332 EKEQRVQQLESELSKKRKKCESLEQEARKKQRRCEELELQLRQAQNENARLVEENSRLSG 391 Query: 135 KYSQKEDIYEEEIKI---LTDKLKEAETRAEFTERLVAKLEKTTDDLEY 180 + ++KE + E ++ L +E ++ ++ L +KLE L++ Sbjct: 392 RATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQVLKH 440
>gi|18202489|sp|Q12852|M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 (Leucine-zipper protein kinase) (ZPK) Length = 859 Score = 26.2 bits (56), Expect = 8.1 Identities = 22/83 (26%), Positives = 35/83 (42%), Gaps = 6/83 (7%) Query: 129 LSDAEEKYSQKEDIYEEEIKILTDKLKEAET-----RAEFTERLVAKLEKTTDDLE-YKL 182 LS +E Y + + + EE+K+ +K+K T E R +L D E Y+ Sbjct: 372 LSTPQETYFKSQAEWREEVKLHFEKIKSEGTCLHRLEEELVMRRREELRHALDIREHYER 431 Query: 183 KCNKEENLCTQRMLYQTLLDLNE 205 K + NL + L+L E Sbjct: 432 KLERANNLYMELNALMLQLELKE 454
>gi|38372433|sp|Q15424|SAFB1_HUMAN Scaffold attachment factor B (Scaffold attachment factor B1) (SAF-B) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein) Length = 915 Score = 26.2 bits (56), Expect = 8.1 Identities = 24/113 (21%), Positives = 49/113 (43%), Gaps = 3/113 (2%) Query: 78 EEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYS 137 ++AD E + ++EG+++ E+ + +ET + + L + EE Sbjct: 151 DDADNLQESLSDSRELVEGEMKELPEQLQEHAIEDKETINNLDTSSSDFTILQEIEEPSL 210 Query: 138 QKEDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDLEYKLKCNKEENL 190 + E+ E+ + IL + K + E +E L + T + K +EE+L Sbjct: 211 EPEN--EKILDILGETCKSEPVKEESSE-LEQPFAQDTSSVGPDRKLAEEEDL 260
>gi|45645200|sp|Q92599|SEP8_HUMAN Septin 8 Length = 483 Score = 26.2 bits (56), Expect = 8.1 Identities = 15/71 (21%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query: 102 EERAELAESRCQETDEQIRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRA 161 EE ++ ++ +ET+ +++ ++ L EK+ + +++EE + + +K +E E Sbjct: 342 EEMRQMFVNKVKETELELKEKEREL------HEKFEHLKRVHQEEKRKVEEKRRELEEET 395 Query: 162 EFTERLVAKLE 172 R A +E Sbjct: 396 NAFNRRKAAVE 406
>gi|14548075|sp|O14645|IDLC_HUMAN Axonemal dynein light intermediate polypeptide 1 (Inner dynein arm light chain, axonemal) (hp28) Length = 257 Score = 26.2 bits (56), Expect = 8.1 Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 5/60 (8%) Query: 140 EDIYEEEIKILTDKLKEAETRAEFTERLVAKLEKTTDDL-----EYKLKCNKEENLCTQR 194 + +YE + K +AE ER +A+LE DL E K KC E ++R Sbjct: 164 QTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESER 223
>gi|55976571|sp|Q96L91|EP400_HUMAN E1A binding protein p400 (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein) Length = 3160 Score = 26.2 bits (56), Expect = 8.1 Identities = 12/53 (22%), Positives = 28/53 (52%) Query: 119 IRLMDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAEFTERLVAKL 171 +R D +++ + EE+ +K ++ +E+K++T K + T +L K+ Sbjct: 418 LRQNDLDIEEEEEEEEEEEEKSEVINDEVKVVTGKDGQTGTPVAIATQLPPKV 470
>gi|22653668|sp|Q9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain 2B (hWALp4) Length = 1972 Score = 26.2 bits (56), Expect = 8.1 Identities = 19/103 (18%), Positives = 47/103 (45%), Gaps = 16/103 (15%) Query: 65 MKEIQLKEAKHIAEEADRKYEEVPRKLVIIEGDLECTEERAELAESRCQETDEQIRL--- 121 ++++Q +E +A+EA ++ + + E+R + + + + E+I+ Sbjct: 708 LRKLQKQEQARVAKEAKKQ-----------QAIMAAEEKRKQKEQIKIMKQQEKIKRIQQ 756 Query: 122 --MDQNLKCLSDAEEKYSQKEDIYEEEIKILTDKLKEAETRAE 162 M++ L+ E K +KE+ ++ ++KE E R + Sbjct: 757 IRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 799
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.311 0.128 0.338 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 366,401 Number of Sequences: 164271 Number of extensions: 14951 Number of successful extensions: 170 Number of sequences better than 10.0: 36 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 108 Number of HSP's gapped (non-prelim): 88 length of query: 206 length of database: 6,424,444 effective HSP length: 91 effective length of query: 115 effective length of database: 5,341,089 effective search space: 614225235 effective search space used: 614225235 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 56 (26.2 bits)
