RID=1111166703-22931-208336078667.BLASTQ4, GENSCAN (8): 1123aa, chain (-)

BLASTP 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402.
RID: 1111166703-22931-208336078667.BLASTQ4
Query= GENSCAN (8): 1123aa, chain (-) (1123 letters)
Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters
If you have any problems or questions with the results of this search
please refer to the BLAST FAQs
Taxonomy reports
Distribution of 463 Blast Hits on the Query Sequence


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52788238|sp|P20719|HXA5_HUMAN  Homeobox protein Hox-A5 (H...   404   e-113 
gi|17378385|sp|P31267|HXA6_HUMAN  Homeobox protein Hox-A6 (H...   399   e-111 
gi|3915721|sp|P31268|HXA7_HUMAN  Homeobox protein Hox-A7 (Ho...   312   5e-85 
gi|400000|sp|P09067|HXB5_HUMAN  Homeobox protein Hox-B5 (Hox...   265   9e-71 
gi|123255|sp|P09629|HXB7_HUMAN  Homeobox protein Hox-B7 (Hox...   183   3e-46 
gi|13124738|sp|P17509|HXB6_HUMAN  Homeobox protein Hox-B6 (H...   167   2e-41 
gi|20141493|sp|P09630|HXC6_HUMAN  Homeobox protein Hox-C6 (H...   164   1e-40 
gi|547692|sp|P17483|HXB4_HUMAN  Homeobox protein Hox-B4 (Hox...   146   5e-35 
gi|232262|sp|Q00444|HXC5_HUMAN  Homeobox protein Hox-C5 (Hox...   144   2e-34 
gi|6166217|sp|Q00056|HXA4_HUMAN  Homeobox protein Hox-A4 (Ho...   142   5e-34 
gi|20141491|sp|P09016|HXD4_HUMAN  Homeobox protein Hox-D4 (H...   139   6e-33 
gi|123279|sp|P09017|HXC4_HUMAN  Homeobox protein Hox-C4 (Hox...   139   6e-33 
gi|13124737|sp|P13378|HXD8_HUMAN  Homeobox protein Hox-D8 (H...   124   2e-28 
gi|13124745|sp|P31273|HXC8_HUMAN  Homeobox protein Hox-C8 (H...   122   9e-28 
gi|20141506|sp|P17481|HXB8_HUMAN  Homeobox protein Hox-B8 (H...   118   1e-26 
gi|123268|sp|P14651|HXB3_HUMAN  Homeobox protein Hox-B3 (Hox...   104   2e-22 
gi|6016293|sp|O43365|HXA3_HUMAN  Homeobox protein Hox-A3 (Ho...   101   1e-21 
gi|6166222|sp|P31249|HXD3_HUMAN  Homeobox protein Hox-D3 (Ho...   101   2e-21 
gi|1708540|sp|P52945|IPF1_HUMAN  Insulin promoter factor-1 (...    98   2e-20 
gi|123286|sp|P28356|HXD9_HUMAN  Homeobox protein Hox-D9 (Hox...    92   1e-18 
gi|20141537|sp|P31274|HXC9_HUMAN  Homeobox protein Hox-C9 (H...    92   1e-18 
gi|123270|sp|P14652|HXB2_HUMAN  Homeobox protein Hox-B2 (Hox...    92   1e-18 
gi|6166219|sp|P31269|HXA9_HUMAN  Homeobox protein Hox-A9 (Ho...    89   7e-18 
gi|6016292|sp|O43364|HXA2_HUMAN  Homeobox protein Hox-A2           89   9e-18 
gi|20141507|sp|P17482|HXB9_HUMAN  Homeobox protein Hox-B9 (H...    88   1e-17 
gi|13124743|sp|P31260|HXA10_HUMAN  Homeobox protein Hox-A10 ...    87   3e-17 
gi|1345720|sp|P47902|CDX1_HUMAN  Homeobox protein CDX-1 (Cau...    87   3e-17 
gi|20141612|sp|Q9NYD6|HXC10_HUMAN  Homeobox protein Hox-C10        86   7e-17 
gi|123289|sp|P28358|HXD10_HUMAN  Homeobox protein Hox-D10 (H...    85   1e-16 
gi|27923786|sp|Q9H4S2|GSHI_HUMAN  Homeobox protein GSH-1           85   2e-16 
gi|20138327|sp|Q9BZM3|GSH2_HUMAN  Homeobox protein GSH-2           85   2e-16 
gi|123271|sp|P14653|HXB1_HUMAN  Homeobox protein Hox-B1 (Hox...    83   6e-16 
gi|6166216|sp|P49639|HXA1_HUMAN  Homeobox protein Hox-A1 (Ho...    82   8e-16 
gi|45644931|sp|P50219|HLXB9_HUMAN  Homeobox protein HB9            82   1e-15 
gi|20141282|sp|Q99626|CDX2_HUMAN  Homeobox protein CDX-2 (Ca...    82   1e-15 
gi|17378648|sp|Q9GZZ0|HXD1_HUMAN  Homeobox protein Hox-D1          81   2e-15 
gi|1709078|sp|P50221|MEOX1_HUMAN  Homeobox protein MOX-1 (Me...    81   2e-15 
gi|12230077|sp|Q14549|GBX1_HUMAN  Homeobox protein GBX-1 (Ga...    81   2e-15 
gi|12644308|sp|P52951|GBX2_HUMAN  Homeobox protein GBX-2 (Ga...    79   7e-15 
gi|3023467|sp|O14627|CDX4_HUMAN  Homeobox protein CDX-4 (Cau...    79   9e-15 
gi|399982|sp|P31314|TLX1_HUMAN  T-cell leukemia homeobox pro...    79   9e-15 
gi|13124744|sp|P31270|HXA11_HUMAN  Homeobox protein Hox-A11 ...    78   2e-14 
gi|12644203|sp|P31277|HXD11_HUMAN  Homeobox protein Hox-D11 ...    76   6e-14 
gi|3287858|sp|O43248|HXC11_HUMAN  Homeobox protein Hox-C11         76   8e-14 
gi|1709079|sp|P50222|MEOX2_HUMAN  Homeobox protein MOX-2 (Me...    75   1e-13 
gi|23831508|sp|O43711|TLX3_HUMAN  T-cell leukemia homeobox p...    74   3e-13 
gi|20532396|sp|O43763|TLX2_HUMAN  T-cell leukemia homeobox p...    72   1e-12 
gi|14194481|sp|Q9HBU1|BARX1_HUMAN  Homeobox protein BarH-like 1    69   9e-12 
gi|12644227|sp|P35452|HXD12_HUMAN  Homeobox protein Hox-D12 ...    68   2e-11 
gi|12231013|sp|Q03828|EVX2_HUMAN  Homeobox even-skipped homo...    68   2e-11 
gi|14917010|sp|Q05925|HME1_HUMAN  Homeobox protein engrailed...    68   2e-11 
gi|21903415|sp|P19622|HME2_HUMAN  Homeobox protein engrailed...    67   3e-11 
gi|547658|sp|Q03014|HHEX_HUMAN  Homeobox protein PRH (Hemato...    67   4e-11 
gi|1352398|sp|P49640|EVX1_HUMAN  Homeobox even-skipped homol...    67   5e-11 
gi|27923733|sp|Q96QS3|ARX_HUMAN  Homeobox protein ARX (Arist...    67   5e-11 
gi|20141538|sp|P31275|HXC12_HUMAN  Homeobox protein Hox-C12 ...    67   5e-11 
gi|20532295|sp|Q9UIW0|VAX2_HUMAN  Ventral anterior homeobox 2      65   1e-10 
gi|29336920|sp|Q9BZE3|BARH1_HUMAN  BarH-like 1 homeobox prot...    65   1e-10 
gi|6016211|sp|P78426|NK61_HUMAN  Homeobox protein Nkx-6.1          65   1e-10 
gi|2828197|sp|P31271|HXA13_HUMAN  Homeobox protein Hox-A13 (...    65   1e-10 
gi|6016210|sp|P78367|NK32_HUMAN  Homeobox protein Nkx-3.2 (B...    65   2e-10 
gi|13431329|sp|Q9UMQ3|BARX2_HUMAN  Homeobox protein BarH-like 2    64   2e-10 
gi|19862512|sp|Q04743|EMX2_HUMAN  Homeobox protein EMX2 (Emp...    63   5e-10 
gi|47117915|sp|Q9NY43|BARH2_HUMAN  BarH-like 2 homeobox protein    63   5e-10 
gi|27923815|sp|Q8TAU0|NKX23_HUMAN  Homeobox protein Nkx-2.3 ...    63   5e-10 
gi|50403792|sp|Q92826|HXB13_HUMAN  Homeobox protein Hox-B13        62   9e-10 
gi|2833256|sp|Q14774|HLX1_HUMAN  Homeobox protein HLX1 (Home...    62   9e-10 
gi|20141539|sp|P31276|HXC13_HUMAN  Homeobox protein Hox-C13 ...    62   1e-09 
gi|2851475|sp|P35453|HXD13_HUMAN  Homeobox protein Hox-D13 (...    61   2e-09 
gi|57015304|sp|Q04741|EMX1_HUMAN  Homeobox protein EMX1 (Emp...    61   3e-09 
gi|6016208|sp|O15522|NK28_HUMAN  Homeobox protein Nkx-2.8 (H...    60   4e-09 
gi|17377578|sp|Q99801|NKX31_HUMAN  Homeobox protein Nkx-3.1        59   7e-09 
gi|27923817|sp|Q9H2Z4|NK24_HUMAN  Homeobox protein Nkx-2.4 (...    59   7e-09 
gi|23503066|sp|P28360|MSX1_HUMAN  Homeobox protein MSX-1 (Ho...    59   1e-08 
gi|1708211|sp|P52952|NK25_HUMAN  Homeobox protein Nkx-2.5 (H...    59   1e-08 
gi|1174819|sp|P43699|TITF1_HUMAN  Thyroid transcription fact...    59   1e-08 
gi|3913487|sp|O60479|DLX3_HUMAN  Homeobox protein DLX-3            59   1e-08 
gi|17380297|sp|Q9Y2V3|RX_HUMAN  Retinal homeobox protein Rx ...    59   1e-08 
gi|13959687|sp|P35548|MSX2_HUMAN  Homeobox protein MSX-2 (Ho...    58   2e-08 
gi|1730095|sp|P52954|LBX1_HUMAN  Transcription factor LBX1         58   2e-08 
gi|12644329|sp|P56178|DLX5_HUMAN  Homeobox protein DLX-5           57   3e-08 
gi|13626112|sp|Q9H161|ALX4_HUMAN  Homeobox protein aristales...    57   4e-08 
gi|2506529|sp|Q07687|DLX2_HUMAN  Homeobox protein DLX-2            57   5e-08 
gi|48428084|sp|Q8N693|ESX1L_HUMAN  Extraembryonic, spermatog...    57   5e-08 
gi|12644330|sp|P56179|DLX6_HUMAN  Homeobox protein DLX-6           56   6e-08 
gi|3024482|sp|P78337|PITX1_HUMAN  Pituitary homeobox 1 (Hind...    56   8e-08 
gi|6016205|sp|O95096|NKX22_HUMAN  Homeobox protein Nkx-2.2 (...    55   1e-07 
gi|8247951|sp|P23759|PAX7_HUMAN  Paired box protein Pax-7 (H...    55   1e-07 
gi|38605720|sp|P56177|DLX1_HUMAN  Homeobox protein DLX-1           55   1e-07 
gi|6174907|sp|Q99697|PITX2_HUMAN  Pituitary homeobox 2 (RIEG...    55   2e-07 
gi|6093723|sp|O75364|PITX3_HUMAN  Pituitary homeobox 3 (Home...    54   2e-07 
gi|3023579|sp|Q15699|CRT1_HUMAN  Cartilage homeoprotein 1 (C...    54   2e-07 
gi|51702790|sp|P63015|PAX6_MOUSE  Paired box protein Pax-6 (...    54   3e-07 
gi|13626107|sp|O95076|ALX3_HUMAN  Homeobox protein aristales...    54   4e-07 
gi|3287764|sp|O43186|CRX_HUMAN  Cone-rod homeobox protein          53   5e-07 
gi|3914276|sp|O43316|PAX4_HUMAN  Paired box protein Pax-4          53   5e-07 
gi|17374365|sp|P58304|CHX10_HUMAN  Homeobox protein CHX10 (C...    52   1e-06 
gi|12230168|sp|Q9UBX0|HESX1_HUMAN  Homeobox expressed in ES ...    52   2e-06 
gi|8134644|sp|Q99453|PHX2B_HUMAN  Paired mesoderm homeobox p...    52   2e-06 
gi|3915680|sp|Q92988|DLX4_HUMAN  Homeobox protein DLX-4 (DLX...    52   2e-06 
gi|1172022|sp|P23760|PAX3_HUMAN  Paired box protein Pax-3 (H...    51   2e-06 
gi|8134640|sp|O14813|PHX2A_HUMAN  Paired mesoderm homeobox p...    51   3e-06 
gi|25009572|sp|Q9NZR4|VSX1_HUMAN  Visual system homeobox 1 (...    50   4e-06 
gi|18202099|sp|O60902|SHOX2_HUMAN  Short stature homeobox pr...    49   8e-06 
gi|6093787|sp|O75360|PROP1_HUMAN  Homeobox protein prophet o...    49   1e-05 
gi|6831676|sp|O15266|SHOX_HUMAN  Short stature homeobox prot...    47   3e-05 
gi|12644475|sp|Q99811|PRRX2_HUMAN  Paired mesoderm homeobox ...    46   6e-05 
gi|12644347|sp|P78413|IRX4_HUMAN  Iroquois-class homeodomain...    45   1e-04 
gi|7531125|sp|P56915|GSC_HUMAN  Homeobox protein goosecoid         45   1e-04 
gi|6174916|sp|P54821|PRRX1_HUMAN  Paired mesoderm homeobox p...    44   2e-04 
gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN  Zinc finger homeobox prot...    44   2e-04 
gi|37537987|sp|Q9BQY4|PEP2_HUMAN  Paired-like homeobox prote...    44   3e-04 
gi|6685480|sp|O15499|GSCL_HUMAN  Homeobox protein goosecoid-...    44   3e-04 
gi|417425|sp|P32242|OTX1_HUMAN  Homeobox protein OTX1              44   3e-04 
gi|417427|sp|P32243|OTX2_HUMAN  Homeobox protein OTX2              44   3e-04 
gi|47117874|sp|P78415|IRX3_HUMAN  Iroquois-class homeodomain...    44   3e-04 
gi|47117872|sp|P78412|IRX6_HUMAN  Iroquois-class homeodomain...    42   0.002 
gi|37537960|sp|Q8NHV9|PEPP1_HUMAN  Paired-like homeobox prot...    41   0.003 
gi|47117908|sp|Q9BZI1|IRX2_HUMAN  Iroquois-class homeodomain...    40   0.006 
gi|47117871|sp|P78411|IRX5_HUMAN  Iroquois-class homeodomain...    39   0.008 
gi|28202257|sp|P14859|PO2F1_HUMAN  POU domain, class 2, tran...    39   0.013 
gi|123402|sp|P09086|PO2F2_HUMAN  POU domain, class 2, transc...    39   0.013 
gi|18202510|sp|Q15911|ATBF1_HUMAN  Alpha-fetoprotein enhance...    39   0.013 
gi|27923801|sp|Q8TE12|LMX1A_HUMAN  LIM homeobox transcriptio...    38   0.018 
gi|8247930|sp|O60663|LMX1B_HUMAN  LIM homeobox transcription...    38   0.018 
gi|12643415|sp|Q9UBR4|LHX3_HUMAN  LIM/homeobox protein Lhx3        38   0.023 
gi|8247936|sp|P50458|LHX2_HUMAN  LIM/homeobox protein Lhx2 (...    37   0.039 
gi|730281|sp|P40426|PBX3_HUMAN  Pre-B-cell leukemia transcri...    37   0.039 
gi|12643346|sp|Q9NQ69|LHX9_HUMAN  LIM/homeobox protein Lhx9        37   0.039 
gi|8134548|sp|Q9UPM6|LHX61_HUMAN  LIM/homeobox protein Lhx6....    37   0.039 
gi|18202938|sp|Q9H2C1|LHX5_HUMAN  LIM/homeobox protein Lhx5        37   0.051 
gi|1352729|sp|P40425|PBX2_HUMAN  Pre-B-cell leukemia transcr...    37   0.051 
gi|47117873|sp|P78414|IRX1_HUMAN  Iroquois-class homeodomain...    37   0.051 
gi|28201884|sp|P78424|PO6F2_HUMAN  POU domain, class 6, tran...    37   0.051 
gi|20138668|sp|Q969G2|LHX4_HUMAN  LIM/homeobox protein Lhx4        36   0.067 
gi|20141754|sp|P41778|PBX1_MOUSE  Pre-B-cell leukemia transc...    36   0.087 
gi|37999770|sp|Q9BYU1|PBX4_HUMAN  Pre-B-cell leukemia transc...    36   0.087 
gi|60416412|sp|P48742|LHX1_HUMAN  LIM/homeobox protein Lhx1 ...    35   0.11  
gi|2495300|sp|Q12837|PO42_HUMAN  POU domain, class 4, transc...    35   0.11  
gi|12230598|sp|Q9NPC8|SIX2_HUMAN  Homeobox protein SIX2 (Sin...    35   0.15  
gi|28201861|sp|Q9UKI9|PO2F3_HUMAN  POU domain, class 2, tran...    35   0.15  
gi|2495306|sp|Q14863|PO6F1_HUMAN  POU domain, class 6, trans...    35   0.19  
gi|37999860|sp|O14686|MLL2_HUMAN  Myeloid/lymphoid or mixed-...    35   0.19  
gi|2495302|sp|Q15319|PO43_HUMAN  POU domain, class 4, transc...    34   0.25  
gi|12230612|sp|Q9UIU6|SIX4_HUMAN  Homeobox protein SIX4 (Sin...    34   0.25  
gi|20978495|sp|Q96A47|ISL2_HUMAN  Insulin gene enhancer prot...    33   0.43  
gi|2506535|sp|Q01851|PO4F1_HUMAN  POU domain, class 4, trans...    33   0.43  
gi|20141591|sp|Q15811|ITN1_HUMAN  Intersectin 1 (SH3 domain-...    33   0.57  
gi|2495290|sp|Q15475|SIX1_HUMAN  Homeobox protein SIX1 (Sine...    32   0.96  
gi|47606423|sp|P61371|ISL1_HUMAN  Insulin gene enhancer prot...    32   0.96  
gi|400659|sp|Q01860|PO5F1_HUMAN  POU domain, class 5, transc...    32   1.3   
gi|47116024|sp|Q8WXF8|DEDD2_HUMAN  DNA-binding death effecto...    32   1.6   
gi|32172435|sp|P46934|NEDD4_HUMAN  E3 ubiquitin-protein liga...    32   1.6   
gi|1709437|sp|Q03052|PO3F1_HUMAN  POU domain, class 3, trans...    31   2.1   
gi|44888551|sp|Q9UKY1|ZHX1_HUMAN  Zinc fingers and homeoboxe...    31   2.8   
gi|28201858|sp|Q06416|PO5L_HUMAN  POU domain, class 5, trans...    31   2.8   
gi|28201859|sp|Q9BZV7|PO5M_HUMAN  POU domain, class 5, trans...    31   2.8   
gi|123408|sp|P28069|PIT1_HUMAN  Pituitary-specific positive ...    30   4.8   
gi|52000732|sp|Q99700|ATX2_HUMAN  Ataxin-2 (Spinocerebellar ...    30   6.2   
gi|44889075|sp|Q9H4I2|ZHX3_HUMAN  Zinc fingers and homeoboxe...    29   8.2   
gi|6094293|sp|O95343|SIX3_HUMAN  Homeobox protein SIX3 (Sine...    29   8.2   
gi|2506534|sp|P20264|PO33_HUMAN  POU domain, class 3, transc...    29   8.2   


Alignments

>gi|52788238|sp|P20719|HXA5_HUMAN   Homeobox protein Hox-A5 (Hox-1C)
          Length = 270

 Score =  404 bits (1039), Expect = e-113
 Identities = 199/270 (73%), Positives = 199/270 (73%)

Query: 854  MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 913
            MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG
Sbjct: 1    MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 60

Query: 914  SGHFXXXXXXXXXXXXXXXXXXXXXXXQPATSTHSPQPDPLPCSAVAPSPGSDXXXXXXX 973
            SGHF                       QPATSTHSPQPDPLPCSAVAPSPGSD       
Sbjct: 61   SGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKN 120

Query: 974  XXXXXXXXXXXXXXTHISSREGVGTASGXXXXXXXXXXXXXXXXXXXXXXXXXXXIYPWM 1033
                          THISSREGVGTASG                           IYPWM
Sbjct: 121  SLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWM 180

Query: 1034 RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK 1093
            RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK
Sbjct: 181  RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK 240

Query: 1094 IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 1123
            IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP
Sbjct: 241  IWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 270



 Score =  134 bits (336), Expect = 2e-31
 Identities = 75/152 (49%), Positives = 90/152 (59%), Gaps = 20/152 (13%)

Query: 225 SPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFR 284
           S +  SP +  +  G ++  N   AS D     + S    G     +E A   + +A+ +
Sbjct: 104 SAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQ 163

Query: 285 ------------IYPWMRS--------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRR 324
                       IYPWMR          GP+ KR R  YTRYQTLELEKEFHFNRYLTRR
Sbjct: 164 SEPSPAPPAQPQIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRR 223

Query: 325 RRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           RRIEIAHALCL+ERQIKIWFQNRRMKWKK++K
Sbjct: 224 RRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 255



 Score =  114 bits (286), Expect = 1e-25
 Identities = 73/201 (36%), Positives = 99/201 (49%), Gaps = 9/201 (4%)

Query: 514 LGSSEAGYDALRPFPASYGASSLP---DKTYTSPCFYQQSNSV--LACNRASYEYGASCF 568
           +G S +G+        SY AS+     +  Y+ P     S     L C+  +   G+   
Sbjct: 56  VGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSH 115

Query: 569 YSDKDL----SGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSP 624
           +  K+     SGAS           + +  +   +    +SS Q  A  +          
Sbjct: 116 HGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQ 175

Query: 625 VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLT 684
           +YPWM++++     + G               LELEKEFHFNRYLTRRRRIEIA+ALCL+
Sbjct: 176 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 235

Query: 685 ERQIKIWFQNRRMKWKKENKL 705
           ERQIKIWFQNRRMKWKK+NKL
Sbjct: 236 ERQIKIWFQNRRMKWKKDNKL 256



>gi|17378385|sp|P31267|HXA6_HUMAN   Homeobox protein Hox-A6 (Hox-1B)
          Length = 233

 Score =  399 bits (1025), Expect = e-111
 Identities = 191/205 (93%), Positives = 192/205 (93%)

Query: 518 EAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGA 577
           +AGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGA
Sbjct: 29  QAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGA 88

Query: 578 SPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAG 637
           SPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAG
Sbjct: 89  SPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAG 148

Query: 638 AVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRM 697
           AVYGSH             LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRM
Sbjct: 149 AVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRM 208

Query: 698 KWKKENKLINSTQPSGEDSEAKAGE 722
           KWKKENKLINSTQPSGEDSEAKAGE
Sbjct: 209 KWKKENKLINSTQPSGEDSEAKAGE 233



 Score =  134 bits (336), Expect = 2e-31
 Identities = 60/81 (74%), Positives = 70/81 (86%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            +YPWM++++     + G  G+R R  YTRYQTLELEKEFHFNRYLTRRRRIEIA+ALCL+
Sbjct: 136  VYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLT 195

Query: 1089 ERQIKIWFQNRRMKWKKDNKL 1109
            ERQIKIWFQNRRMKWKK+NKL
Sbjct: 196  ERQIKIWFQNRRMKWKKENKL 216



 Score =  129 bits (324), Expect = 6e-30
 Identities = 62/80 (77%), Positives = 67/80 (83%), Gaps = 8/80 (10%)

Query: 285 IYPWMRSS--------GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 336
           +YPWM+          G   +RGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIA+ALCLT
Sbjct: 136 VYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLT 195

Query: 337 ERQIKIWFQNRRMKWKKEHK 356
           ERQIKIWFQNRRMKWKKE+K
Sbjct: 196 ERQIKIWFQNRRMKWKKENK 215



>gi|3915721|sp|P31268|HXA7_HUMAN   Homeobox protein Hox-A7 (Hox-1A) (Hox 1.1)
          Length = 230

 Score =  312 bits (799), Expect = 5e-85
 Identities = 154/175 (88%), Positives = 154/175 (88%), Gaps = 3/175 (1%)

Query: 203 RSXXXXXXXXXXSTVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDL 262
           RS          STVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDL
Sbjct: 37  RSGYGAGAGAFASTVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDL 96

Query: 263 AKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLT 322
           AKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLT
Sbjct: 97  AKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLT 156

Query: 323 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEA-QAHQPPLLEGNVPELAA 376
           RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDE   A   P  EG VP  AA
Sbjct: 157 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAP--EGAVPSAAA 209



 Score =  133 bits (335), Expect = 3e-31
 Identities = 65/89 (73%), Positives = 71/89 (79%), Gaps = 8/89 (8%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            IYPWMR          GP+ KR R  YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL+
Sbjct: 119  IYPWMRS--------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 170

Query: 1089 ERQIKIWFQNRRMKWKKDNKLKSMSMAAA 1117
            ERQIKIWFQNRRMKWKK++K +  + AAA
Sbjct: 171  ERQIKIWFQNRRMKWKKEHKDEGPTAAAA 199



 Score =  103 bits (258), Expect = 3e-22
 Identities = 80/197 (40%), Positives = 95/197 (48%), Gaps = 30/197 (15%)

Query: 529 ASYGASSLPDKTYTSPCFYQQSNSVLACN------RASYEYGASCF-------YSDKDLS 575
           +SY  ++L  K YT+     Q+    +C+      R+ Y  GA  F       Y+     
Sbjct: 3   SSYYVNALFSK-YTAGTSLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPL 61

Query: 576 GASPSGSGKQRGPGDY--LHFSPEQQYKPDSSSGQGKAL---HDEGA---DRKYTSPVYP 627
             SP  SG   G   Y  L  +   Q  P   S   K      DEGA     +    +YP
Sbjct: 62  YQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYP 121

Query: 628 WMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQ 687
           WM+          G               LELEKEFHFNRYLTRRRRIEIA+ALCLTERQ
Sbjct: 122 WMRSS--------GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQ 173

Query: 688 IKIWFQNRRMKWKKENK 704
           IKIWFQNRRMKWKKE+K
Sbjct: 174 IKIWFQNRRMKWKKEHK 190



>gi|400000|sp|P09067|HXB5_HUMAN   Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1)
          Length = 269

 Score =  265 bits (676), Expect = 9e-71
 Identities = 148/277 (53%), Positives = 161/277 (58%), Gaps = 15/277 (5%)

Query: 854  MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSG 913
            MSSYFVNSF GRYPNGPDYQL NYG  SS+S  +RD A+MH+G YGY YNGMDLSV RS 
Sbjct: 1    MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS 60

Query: 914  --SGHFXXXXXXXXXXXXXXXXXXXXXXXQPATSTHSPQPDPLPCS-----AVAPSPGSD 966
              S HF                       Q A+S     P+ LPC+        PS  S 
Sbjct: 61   ASSSHFGAVGESSRAFPAPAQEPRFR---QAASSCSLSSPESLPCTNGDSHGAKPSASSP 117

Query: 967  XXXXXXXXXXXXXXXXXXXXXTHISSREGVGTASGXXXXXXXXXXXXXXXXXXXXXXXXX 1026
                                    +S E    AS                          
Sbjct: 118  SDQATSASSSANFTEIDEAS----ASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQT 173

Query: 1027 XXIYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 1086
              I+PWMRKLHISHD + GP+GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC
Sbjct: 174  PQIFPWMRKLHISHD-MTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 232

Query: 1087 LSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 1123
            LSERQIKIWFQNRRMKWKKDNKLKSMS+A AG AF+P
Sbjct: 233  LSERQIKIWFQNRRMKWKKDNKLKSMSLATAGSAFQP 269



 Score =  132 bits (331), Expect = 9e-31
 Identities = 62/80 (77%), Positives = 68/80 (85%), Gaps = 7/80 (8%)

Query: 284 RIYPWMRS-------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 336
           +I+PWMR        +GPD KR R  YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL+
Sbjct: 175 QIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 234

Query: 337 ERQIKIWFQNRRMKWKKEHK 356
           ERQIKIWFQNRRMKWKK++K
Sbjct: 235 ERQIKIWFQNRRMKWKKDNK 254



 Score =  107 bits (266), Expect = 3e-23
 Identities = 51/84 (60%), Positives = 62/84 (73%), Gaps = 1/84 (1%)

Query: 622 TSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANAL 681
           T  ++PWM++++  +  + G               LELEKEFHFNRYLTRRRRIEIA+AL
Sbjct: 173 TPQIFPWMRKLH-ISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL 231

Query: 682 CLTERQIKIWFQNRRMKWKKENKL 705
           CL+ERQIKIWFQNRRMKWKK+NKL
Sbjct: 232 CLSERQIKIWFQNRRMKWKKDNKL 255



>gi|123255|sp|P09629|HXB7_HUMAN   Homeobox protein Hox-B7 (Hox-2C) (HHO.C1)
          Length = 217

 Score =  183 bits (465), Expect = 3e-46
 Identities = 91/128 (71%), Positives = 105/128 (82%), Gaps = 7/128 (5%)

Query: 232 FASGYGLGADAYGNLPCASYDQNIPGLC---SDLAKGACDKTDEGALHGAAEANFRIYPW 288
           +A+GYGL   ++ N+ CA ++QN+ G+C   S  A GA ++ D      AAE+NFRIYPW
Sbjct: 74  YAAGYGLEPSSF-NMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDL---AAESNFRIYPW 129

Query: 289 MRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRR 348
           MRSSG DRKRGRQTYTRYQTLELEKEFH+NRYLTRRRRIEIAH LCLTERQIKIWFQNRR
Sbjct: 130 MRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRR 189

Query: 349 MKWKKEHK 356
           MKWKKE+K
Sbjct: 190 MKWKKENK 197



 Score =  127 bits (318), Expect = 3e-29
 Identities = 60/80 (75%), Positives = 64/80 (80%), Gaps = 8/80 (10%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            IYPWMR          G + KR R  YTRYQTLELEKEFH+NRYLTRRRRIEIAH LCL+
Sbjct: 126  IYPWMRS--------SGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLT 177

Query: 1089 ERQIKIWFQNRRMKWKKDNK 1108
            ERQIKIWFQNRRMKWKK+NK
Sbjct: 178  ERQIKIWFQNRRMKWKKENK 197



 Score =  112 bits (280), Expect = 7e-25
 Identities = 81/216 (37%), Positives = 101/216 (46%), Gaps = 32/216 (14%)

Query: 529 ASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDK-DLSGASPSGSGK--Q 585
           + Y ASS     + +  F +Q++   A N     YGA    S    + G  P G G   Q
Sbjct: 12  SKYPASS---SVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAGSMQGLYPGGGGMAGQ 68

Query: 586 RGPGDY------------LHFSPEQQYKP-----DSSSGQG-KALHDEGADRKYTSPVYP 627
              G Y            +H +P +Q        DS+   G K   D     +    +YP
Sbjct: 69  SAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYP 128

Query: 628 WMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQ 687
           WM+          G+              LELEKEFH+NRYLTRRRRIEIA+ LCLTERQ
Sbjct: 129 WMRSS--------GTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQ 180

Query: 688 IKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEE 723
           IKIWFQNRRMKWKKENK         + +EA+  EE
Sbjct: 181 IKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEE 216



>gi|13124738|sp|P17509|HXB6_HUMAN   Homeobox protein Hox-B6 (Hox-2B) (Hox-2.2) (HU-2)
          Length = 224

 Score =  167 bits (423), Expect = 2e-41
 Identities = 100/218 (45%), Positives = 129/218 (59%), Gaps = 16/218 (7%)

Query: 510 QECLLGSS---EAGY-DALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYG- 564
           QE  LG      +GY D LR +PA YG     DK + +  +Y  +        A  +YG 
Sbjct: 18  QESFLGHVPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYG-RAAPCDYGP 76

Query: 565 ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSP 624
           A  FY +K+ S  + SG+ +Q        F PE +    S   Q K++  E  ++K ++P
Sbjct: 77  APAFYREKE-SACALSGADEQPP------FHPEPR---KSDCAQDKSVFGETEEQKCSTP 126

Query: 625 VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLT 684
           VYPWMQRMNSC  + +G               LELEKEFH+NRYLTRRRRIEIA+ALCLT
Sbjct: 127 VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLT 186

Query: 685 ERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 722
           ERQIKIWFQNRRMKWKKE+KL++++Q S E+ E K  E
Sbjct: 187 ERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 224



 Score =  140 bits (354), Expect = 2e-33
 Identities = 63/89 (70%), Positives = 76/89 (85%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            +YPWM++++  + +  GP G+R R  YTRYQTLELEKEFH+NRYLTRRRRIEIAHALCL+
Sbjct: 127  VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLT 186

Query: 1089 ERQIKIWFQNRRMKWKKDNKLKSMSMAAA 1117
            ERQIKIWFQNRRMKWKK++KL S S  +A
Sbjct: 187  ERQIKIWFQNRRMKWKKESKLLSASQLSA 215



 Score =  136 bits (343), Expect = 4e-32
 Identities = 81/151 (53%), Positives = 90/151 (59%), Gaps = 24/151 (15%)

Query: 228 YQSPFASGYGLGADA-YGNLP---------CA-SYDQNIPGLCSDLAKGACDKTDEGALH 276
           Y  P   GYG  A   YG  P         CA S     P    +  K  C    + ++ 
Sbjct: 58  YYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDC--AQDKSVF 115

Query: 277 GAAE---ANFRIYPWMR--------SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRR 325
           G  E    +  +YPWM+        S GP  +RGRQTYTRYQTLELEKEFH+NRYLTRRR
Sbjct: 116 GETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRR 175

Query: 326 RIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           RIEIAHALCLTERQIKIWFQNRRMKWKKE K
Sbjct: 176 RIEIAHALCLTERQIKIWFQNRRMKWKKESK 206



>gi|20141493|sp|P09630|HXC6_HUMAN   Homeobox protein Hox-C6 (Hox-3C) (HHO.C8) (CP25)
          Length = 235

 Score =  164 bits (416), Expect = 1e-40
 Identities = 89/202 (44%), Positives = 119/202 (58%), Gaps = 13/202 (6%)

Query: 517 SEAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSG 576
           +   YD +R F ++YGA+   ++ Y++P +  Q N V + +R  Y+YG++ FY +KD+  
Sbjct: 27  NSTAYDPVRHF-STYGAAVAQNRIYSTPFYSPQENVVFSSSRGPYDYGSNSFYQEKDMLS 85

Query: 577 ASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCA 636
                +         L  + +     D SS QG+       D+K +  +YPWMQRMNS +
Sbjct: 86  NCRQNT---------LGHNTQTSIAQDFSSEQGRTAPQ---DQKASIQIYPWMQRMNSHS 133

Query: 637 GAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRR 696
           G  YG+              LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRR
Sbjct: 134 GVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRR 193

Query: 697 MKWKKENKLINSTQPSGEDSEA 718
           MKWKKE+ L ++    G  + A
Sbjct: 194 MKWKKESNLTSTLSGGGGGATA 215



 Score =  134 bits (336), Expect = 2e-31
 Identities = 64/93 (68%), Positives = 76/93 (81%), Gaps = 2/93 (2%)

Query: 1029 IYPWMRKLHISHDNIG-GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL 1087
            IYPWM++++ SH  +G G + +R R  Y+RYQTLELEKEFHFNRYLTRRRRIEIA+ALCL
Sbjct: 122  IYPWMQRMN-SHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCL 180

Query: 1088 SERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGA 1120
            +ERQIKIWFQNRRMKWKK++ L S      GGA
Sbjct: 181  TERQIKIWFQNRRMKWKKESNLTSTLSGGGGGA 213



 Score =  131 bits (330), Expect = 1e-30
 Identities = 63/83 (75%), Positives = 70/83 (84%), Gaps = 8/83 (9%)

Query: 280 EANFRIYPWMRSS--------GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAH 331
           +A+ +IYPWM+          G DR+RGRQ Y+RYQTLELEKEFHFNRYLTRRRRIEIA+
Sbjct: 117 KASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIAN 176

Query: 332 ALCLTERQIKIWFQNRRMKWKKE 354
           ALCLTERQIKIWFQNRRMKWKKE
Sbjct: 177 ALCLTERQIKIWFQNRRMKWKKE 199



>gi|547692|sp|P17483|HXB4_HUMAN   Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6)
          Length = 251

 Score =  146 bits (368), Expect = 5e-35
 Identities = 68/94 (72%), Positives = 79/94 (84%), Gaps = 2/94 (2%)

Query: 1029 IYPWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 1086
            +YPWMRK+H+S  + N  G E KR+RTAYTR Q LELEKEFH+NRYLTRRRR+EIAHALC
Sbjct: 141  VYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALC 200

Query: 1087 LSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGA 1120
            LSERQIKIWFQNRRMKWKKD+KL +  + + G A
Sbjct: 201  LSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAA 234



 Score =  122 bits (307), Expect = 5e-28
 Identities = 57/82 (69%), Positives = 64/82 (78%), Gaps = 10/82 (12%)

Query: 285 IYPWMRS----------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 334
           +YPWMR           +G + KR R  YTR Q LELEKEFH+NRYLTRRRR+EIAHALC
Sbjct: 141 VYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALC 200

Query: 335 LTERQIKIWFQNRRMKWKKEHK 356
           L+ERQIKIWFQNRRMKWKK+HK
Sbjct: 201 LSERQIKIWFQNRRMKWKKDHK 222



 Score =  109 bits (273), Expect = 5e-24
 Identities = 61/115 (53%), Positives = 72/115 (62%), Gaps = 6/115 (5%)

Query: 625 VYPWMQRMN-SCAGAVY-GSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALC 682
           VYPWM++++ S     Y G               LELEKEFH+NRYLTRRRR+EIA+ALC
Sbjct: 141 VYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALC 200

Query: 683 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEEPGPTRWVQGEPSDL 737
           L+ERQIKIWFQNRRMKWKK++KL N+   SG      AG   GP     G P  L
Sbjct: 201 LSERQIKIWFQNRRMKWKKDHKLPNTKIRSG----GAAGSAGGPPGRPNGGPRAL 251



>gi|232262|sp|Q00444|HXC5_HUMAN   Homeobox protein Hox-C5 (Hox-3D) (CP11)
          Length = 222

 Score =  144 bits (363), Expect = 2e-34
 Identities = 67/83 (80%), Positives = 76/83 (91%), Gaps = 4/83 (4%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            IYPWM KLH+SH+     +GKR+RT+YTRYQTLELEKEFHFNRYLTRRRRIEIA+ LCL+
Sbjct: 140  IYPWMTKLHMSHET----DGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLN 195

Query: 1089 ERQIKIWFQNRRMKWKKDNKLKS 1111
            ERQIKIWFQNRRMKWKKD+K+KS
Sbjct: 196  ERQIKIWFQNRRMKWKKDSKMKS 218



 Score =  123 bits (308), Expect = 4e-28
 Identities = 75/143 (52%), Positives = 85/143 (59%), Gaps = 13/143 (9%)

Query: 226 PLYQSPFASGYGLGADAYGNLPCASYDQNI--PGLCSDLAKGACDKTDEGALHGAAE--- 280
           P   +  A G+  G D    L    Y Q    P L  + AK + +  +E A  G      
Sbjct: 74  PACSAAAAPGHAPGRDEAAPLNPGMYSQKAARPAL-EERAKSSGEIKEEQAQTGQPAGLS 132

Query: 281 ---ANFRIYPWMR----SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHAL 333
              A  +IYPWM     S   D KR R +YTRYQTLELEKEFHFNRYLTRRRRIEIA+ L
Sbjct: 133 QPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNL 192

Query: 334 CLTERQIKIWFQNRRMKWKKEHK 356
           CL ERQIKIWFQNRRMKWKK+ K
Sbjct: 193 CLNERQIKIWFQNRRMKWKKDSK 215



 Score =  101 bits (252), Expect = 1e-21
 Identities = 48/81 (59%), Positives = 57/81 (70%), Gaps = 4/81 (4%)

Query: 625 VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLT 684
           +YPWM +++      + +              LELEKEFHFNRYLTRRRRIEIAN LCL 
Sbjct: 140 IYPWMTKLHMS----HETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLN 195

Query: 685 ERQIKIWFQNRRMKWKKENKL 705
           ERQIKIWFQNRRMKWKK++K+
Sbjct: 196 ERQIKIWFQNRRMKWKKDSKM 216



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 9/56 (16%)

Query: 854 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSV 909
           MSSY  NSF  + PN P Y +   G++ S SE       + + RY YG  G+DLS+
Sbjct: 1   MSSYVANSFYKQSPNIPAYNMQTCGNYGSASE-------VQASRYCYG--GLDLSI 47



>gi|6166217|sp|Q00056|HXA4_HUMAN   Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4)
          Length = 320

 Score =  142 bits (359), Expect = 5e-34
 Identities = 67/94 (71%), Positives = 77/94 (81%), Gaps = 2/94 (2%)

Query: 1029 IYPWMRKLHISHDN--IGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 1086
            +YPWM+K+H+S  N    G E KR+RTAYTR Q LELEKEFHFNRYLTRRRRIEIAH LC
Sbjct: 194  VYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253

Query: 1087 LSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGA 1120
            LSERQ+KIWFQNRRMKWKKD+KL +  M ++  A
Sbjct: 254  LSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSA 287



 Score =  121 bits (303), Expect = 2e-27
 Identities = 56/82 (68%), Positives = 63/82 (76%), Gaps = 10/82 (12%)

Query: 285 IYPWMRS----------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 334
           +YPWM+           +G + KR R  YTR Q LELEKEFHFNRYLTRRRRIEIAH LC
Sbjct: 194 VYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253

Query: 335 LTERQIKIWFQNRRMKWKKEHK 356
           L+ERQ+KIWFQNRRMKWKK+HK
Sbjct: 254 LSERQVKIWFQNRRMKWKKDHK 275



 Score =  111 bits (278), Expect = 1e-24
 Identities = 55/99 (55%), Positives = 67/99 (67%), Gaps = 2/99 (2%)

Query: 625 VYPWMQRMNSCA--GAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALC 682
           VYPWM++++  A   +  G               LELEKEFHFNRYLTRRRRIEIA+ LC
Sbjct: 194 VYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253

Query: 683 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 721
           L+ERQ+KIWFQNRRMKWKK++KL N+   S   + A AG
Sbjct: 254 LSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAG 292



>gi|20141491|sp|P09016|HXD4_HUMAN   Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13)
          Length = 255

 Score =  139 bits (350), Expect = 6e-33
 Identities = 65/83 (78%), Positives = 73/83 (87%), Gaps = 2/83 (2%)

Query: 1029 IYPWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 1086
            +YPWM+K+H++  + N  G E KR+RTAYTR Q LELEKEFHFNRYLTRRRRIEIAH LC
Sbjct: 133  VYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 192

Query: 1087 LSERQIKIWFQNRRMKWKKDNKL 1109
            LSERQIKIWFQNRRMKWKKD+KL
Sbjct: 193  LSERQIKIWFQNRRMKWKKDHKL 215



 Score =  121 bits (304), Expect = 1e-27
 Identities = 57/82 (69%), Positives = 63/82 (76%), Gaps = 10/82 (12%)

Query: 285 IYPWMRS----------SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 334
           +YPWM+           +G + KR R  YTR Q LELEKEFHFNRYLTRRRRIEIAH LC
Sbjct: 133 VYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 192

Query: 335 LTERQIKIWFQNRRMKWKKEHK 356
           L+ERQIKIWFQNRRMKWKK+HK
Sbjct: 193 LSERQIKIWFQNRRMKWKKDHK 214



 Score =  111 bits (277), Expect = 2e-24
 Identities = 60/124 (48%), Positives = 74/124 (59%), Gaps = 3/124 (2%)

Query: 616 GADRKYTSPVYPWMQRM--NSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRR 673
           G   K  + VYPWM+++  NS      G               LELEKEFHFNRYLTRRR
Sbjct: 124 GTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRR 183

Query: 674 RIEIANALCLTERQIKIWFQNRRMKWKKENKLINST-QPSGEDSEAKAGEEPGPTRWVQG 732
           RIEIA+ LCL+ERQIKIWFQNRRMKWKK++KL N+  + S   S +       P++ +Q 
Sbjct: 184 RIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQP 243

Query: 733 EPSD 736
              D
Sbjct: 244 MAKD 247



>gi|123279|sp|P09017|HXC4_HUMAN   Homeobox protein Hox-C4 (Hox-3E) (CP19)
          Length = 264

 Score =  139 bits (350), Expect = 6e-33
 Identities = 64/91 (70%), Positives = 77/91 (84%), Gaps = 2/91 (2%)

Query: 1029 IYPWMRKLHIS--HDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 1086
            +YPWM+K+H+S  + N  G E KR+R AYTR Q LELEKEFH+NRYLTRRRRIEIAH+LC
Sbjct: 135  VYPWMKKIHVSTVNPNYNGGEPKRSRAAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLC 194

Query: 1087 LSERQIKIWFQNRRMKWKKDNKLKSMSMAAA 1117
            LSERQIKIWFQNRRMKWKKD++L +  + +A
Sbjct: 195  LSERQIKIWFQNRRMKWKKDHRLPNTKVRSA 225



 Score =  121 bits (303), Expect = 2e-27
 Identities = 60/104 (57%), Positives = 70/104 (67%), Gaps = 10/104 (9%)

Query: 263 AKGACDKTDEGALHGAAEANFRIYPWMRS----------SGPDRKRGRQTYTRYQTLELE 312
           A  AC +        AA     +YPWM+           +G + KR R  YTR Q LELE
Sbjct: 113 APPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNGGEPKRSRAAYTRQQVLELE 172

Query: 313 KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KEFH+NRYLTRRRRIEIAH+LCL+ERQIKIWFQNRRMKWKK+H+
Sbjct: 173 KEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHR 216



 Score =  108 bits (271), Expect = 8e-24
 Identities = 73/181 (40%), Positives = 91/181 (50%), Gaps = 25/181 (13%)

Query: 569 YSDKDLSGASPSGSGKQRG--PGDYLHFSPEQQY---KPDSSSG-------------QGK 610
           Y ++  S  S  G G  RG  P    H  PE+     +P   SG             Q  
Sbjct: 62  YPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPA 121

Query: 611 ALHDEGADRKYTSPVYPWMQRMN-SCAGAVY-GSHXXXXXXXXXXXXXLELEKEFHFNRY 668
             H   A  K    VYPWM++++ S     Y G               LELEKEFH+NRY
Sbjct: 122 PDHPSSAASKQPI-VYPWMKKIHVSTVNPNYNGGEPKRSRAAYTRQQVLELEKEFHYNRY 180

Query: 669 LTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL----INSTQPSGEDSEAKAGEEP 724
           LTRRRRIEIA++LCL+ERQIKIWFQNRRMKWKK+++L    + S  P+G      +   P
Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATP 240

Query: 725 G 725
           G
Sbjct: 241 G 241



>gi|13124737|sp|P13378|HXD8_HUMAN   Homeobox protein Hox-D8 (Hox-4E) (Hox-5.4)
          Length = 290

 Score =  124 bits (310), Expect = 2e-28
 Identities = 60/101 (59%), Positives = 78/101 (77%), Gaps = 2/101 (1%)

Query: 284 RIYPWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKI 342
           +++PWMR  + P R+RGRQTY+R+QTLELEKEF FN YLTR+RRIE++HAL LTERQ+KI
Sbjct: 184 QMFPWMRPQAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKI 243

Query: 343 WFQNRRMKWKKE-HKDEAQAHQPPLLEGNVPELAADLWRPR 382
           WFQNRRMKWKKE +KD+    +  + +G   + A +L   R
Sbjct: 244 WFQNRRMKWKKENNKDKFPVSRQEVKDGETKKEAQELEEDR 284



 Score =  105 bits (263), Expect = 7e-23
 Identities = 49/79 (62%), Positives = 60/79 (75%), Gaps = 7/79 (8%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            ++PWMR           P  +R R  Y+R+QTLELEKEF FN YLTR+RRIE++HAL L+
Sbjct: 185  MFPWMRPQ-------AAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHALALT 237

Query: 1089 ERQIKIWFQNRRMKWKKDN 1107
            ERQ+KIWFQNRRMKWKK+N
Sbjct: 238  ERQVKIWFQNRRMKWKKEN 256



 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 57/123 (46%), Positives = 68/123 (55%), Gaps = 12/123 (9%)

Query: 602 PDSSSGQGKALHDEGADRKYTSP--VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLEL 659
           PD  S  G    D     + +SP  ++PWM R  +  G   G               LEL
Sbjct: 160 PDCKSSSGNIGEDPDHLNQSSSPSQMFPWM-RPQAAPGRRRGRQTYSRFQT------LEL 212

Query: 660 EKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAK 719
           EKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN   N  +      E K
Sbjct: 213 EKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKEN---NKDKFPVSRQEVK 269

Query: 720 AGE 722
            GE
Sbjct: 270 DGE 272



>gi|13124745|sp|P31273|HXC8_HUMAN   Homeobox protein Hox-C8 (Hox-3A)
          Length = 242

 Score =  122 bits (305), Expect = 9e-28
 Identities = 54/74 (72%), Positives = 64/74 (86%)

Query: 285 IYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF 344
           ++PWMR   P R+ GRQTY+RYQTLELEKEF FN YLTR+RRIE++HAL LTERQ+KIWF
Sbjct: 138 MFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWF 197

Query: 345 QNRRMKWKKEHKDE 358
           QNRRMKWKKE+  +
Sbjct: 198 QNRRMKWKKENNKD 211



 Score =  103 bits (257), Expect = 3e-22
 Identities = 49/79 (62%), Positives = 59/79 (74%), Gaps = 8/79 (10%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            ++PWMR           P  +  R  Y+RYQTLELEKEF FN YLTR+RRIE++HAL L+
Sbjct: 138  MFPWMRP--------HAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLT 189

Query: 1089 ERQIKIWFQNRRMKWKKDN 1107
            ERQ+KIWFQNRRMKWKK+N
Sbjct: 190  ERQVKIWFQNRRMKWKKEN 208



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 65/177 (36%), Positives = 92/177 (51%), Gaps = 23/177 (12%)

Query: 547 YQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS 606
           YQQ+   L+C+       AS FY  + L   S  G+ ++     Y    P+ +   +++S
Sbjct: 72  YQQNPCSLSCHG-----DASKFYGYEALPRQSLYGAQQEASVVQY----PDCKSSANTNS 122

Query: 607 GQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFN 666
            +G+   ++ +     S ++PWM+         +                LELEKEF FN
Sbjct: 123 SEGQGHLNQNSS---PSLMFPWMRP--------HAPGRRSGRQTYSRYQTLELEKEFLFN 171

Query: 667 RYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEE 723
            YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN   N  +  G   E K  EE
Sbjct: 172 PYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN---NKDKLPGARDEEKVEEE 225



>gi|20141506|sp|P17481|HXB8_HUMAN   Homeobox protein Hox-B8 (Hox-2D) (Hox-2.4)
          Length = 243

 Score =  118 bits (296), Expect = 1e-26
 Identities = 54/76 (71%), Positives = 66/76 (86%), Gaps = 1/76 (1%)

Query: 284 RIYPWMR-SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKI 342
           +++PWMR  +   R+RGRQTY+RYQTLELEKEF FN YLTR+RRIE++HAL LTERQ+KI
Sbjct: 133 QLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKI 192

Query: 343 WFQNRRMKWKKEHKDE 358
           WFQNRRMKWKKE+  +
Sbjct: 193 WFQNRRMKWKKENNKD 208



 Score =  103 bits (257), Expect = 3e-22
 Identities = 49/79 (62%), Positives = 59/79 (74%), Gaps = 7/79 (8%)

Query: 1029 IYPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLS 1088
            ++PWMR              +R R  Y+RYQTLELEKEF FN YLTR+RRIE++HAL L+
Sbjct: 134  LFPWMRPQ-------AAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLT 186

Query: 1089 ERQIKIWFQNRRMKWKKDN 1107
            ERQ+KIWFQNRRMKWKK+N
Sbjct: 187  ERQVKIWFQNRRMKWKKEN 205



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 57/133 (42%), Positives = 77/133 (57%), Gaps = 26/133 (19%)

Query: 588 PGDYLHFSPEQQYK------PD----------SSSGQGKALHDEGADRKYT-SPVYPWMQ 630
           PG++  + P Q+        PD          ++SG G+    EG+++  + + ++PWM 
Sbjct: 82  PGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEA--EGSEQSPSPTQLFPWM- 138

Query: 631 RMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKI 690
           R  + AG   G               LELEKEF FN YLTR+RRIE+++AL LTERQ+KI
Sbjct: 139 RPQAAAGRRRGRQTYSRYQT------LELEKEFLFNPYLTRKRRIEVSHALGLTERQVKI 192

Query: 691 WFQNRRMKWKKEN 703
           WFQNRRMKWKKEN
Sbjct: 193 WFQNRRMKWKKEN 205



>gi|123268|sp|P14651|HXB3_HUMAN   Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7)
          Length = 431

 Score =  104 bits (259), Expect = 2e-22
 Identities = 50/75 (66%), Positives = 59/75 (78%)

Query: 1044 GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            G    KRARTAYT  Q +ELEKEFHFNRYL R RR+E+A+ L LSERQIKIWFQNRRMK+
Sbjct: 184  GSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKY 243

Query: 1104 KKDNKLKSMSMAAAG 1118
            KKD K K ++ ++ G
Sbjct: 244  KKDQKAKGLASSSGG 258



 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 43/65 (66%), Positives = 51/65 (78%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R  YT  Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KK+ K
Sbjct: 189 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQK 248

Query: 357 DEAQA 361
            +  A
Sbjct: 249 AKGLA 253



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 54/110 (49%), Positives = 64/110 (58%), Gaps = 8/110 (7%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 716
           +ELEKEFHFNRYL R RR+E+AN L L+ERQIKIWFQNRRMK+KK+ K       SG  S
Sbjct: 201 VELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPS 260

Query: 717 EAKAGEEPGPTRWVQGEPS---DLGPGWLEEPDPVM--KIFQAGYVSKSN 761
              AG  P P +   G  +    + P + E P P    K  Q  Y   SN
Sbjct: 261 --PAGSPPQPMQSTAGFMNALHSMTPSY-ESPSPPAFGKAHQNAYALPSN 307



>gi|6016293|sp|O43365|HXA3_HUMAN   Homeobox protein Hox-A3 (Hox-1E)
          Length = 443

 Score =  101 bits (252), Expect = 1e-21
 Identities = 50/75 (66%), Positives = 58/75 (77%)

Query: 1044 GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            G    KRARTAYT  Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+
Sbjct: 187  GQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 246

Query: 1104 KKDNKLKSMSMAAAG 1118
            KKD K K M  ++ G
Sbjct: 247  KKDQKGKGMLTSSGG 261



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 43/60 (71%), Positives = 49/60 (81%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R  YT  Q +ELEKEFHFNRYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ K
Sbjct: 192 KRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 251



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 61/151 (40%), Positives = 76/151 (50%), Gaps = 19/151 (12%)

Query: 625 VYPWMQ--RMN------------SCAG--AVYGSHXXXXXXXXXXXXXL-ELEKEFHFNR 667
           ++PWM+  R N            SCAG  +  G               L ELEKEFHFNR
Sbjct: 155 IFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNR 214

Query: 668 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEEPGPT 727
           YL R RR+E+AN L LTERQIKIWFQNRRMK+KK+ K       SG  S +++   PG  
Sbjct: 215 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAG 274

Query: 728 RWVQGEPSDLG--PGWLEEPDPVMKIFQAGY 756
            ++    S +   P   + P P  K  Q  Y
Sbjct: 275 GYLNSMHSLVNSVPYEPQSPPPFSKPPQGTY 305



>gi|6166222|sp|P31249|HXD3_HUMAN   Homeobox protein Hox-D3 (Hox-4A)
          Length = 416

 Score =  101 bits (251), Expect = 2e-21
 Identities = 48/68 (70%), Positives = 55/68 (80%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            GP  KR RTAYT  Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+K
Sbjct: 175  GPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYK 234

Query: 1105 KDNKLKSM 1112
            KD K K +
Sbjct: 235  KDQKAKGI 242



 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 55/119 (46%), Positives = 67/119 (56%), Gaps = 23/119 (19%)

Query: 269 KTDEGALHGAAEANFRIYPWMRSS-----------------------GPDRKRGRQTYTR 305
           K    A   +A  + +I+PWM+ S                       GP  KR R  YT 
Sbjct: 128 KGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTS 187

Query: 306 YQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQP 364
            Q +ELEKEFHFNRYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ K +   H P
Sbjct: 188 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSP 246



 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 74/210 (35%), Positives = 92/210 (43%), Gaps = 33/210 (15%)

Query: 525 RPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGK 584
           +P+P    ASSL      S C  Q S  + A      E   SC    +  +G S  G G 
Sbjct: 32  QPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCM---RPGTGNSQGGGGG 88

Query: 585 QRGPGDYLHFSPEQQ---------YKPDSSSGQGKALHDEGADRKYTSP------VYPWM 629
            + PG      P Q            P +  G   A   +G     +S       ++PWM
Sbjct: 89  SQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWM 148

Query: 630 Q-------RMNSCAGAVY--------GSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRR 674
           +       + NSCA A          G               +ELEKEFHFNRYL R RR
Sbjct: 149 KESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRR 208

Query: 675 IEIANALCLTERQIKIWFQNRRMKWKKENK 704
           +E+AN L LTERQIKIWFQNRRMK+KK+ K
Sbjct: 209 VEMANLLNLTERQIKIWFQNRRMKYKKDQK 238



>gi|1708540|sp|P52945|IPF1_HUMAN   Insulin promoter factor-1 (IPF-1) (Pancreas/duodenum homeobox-1)
            (PDX-1) (Islet/duodenum homeobox-1) (IDX-1) (Somatostatin
            transactivating factor-1) (STF-1) (Insulin upstream
            factor-1) (IUF-1) (Glucose-sensitive factor) (GSF)
          Length = 283

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 53/99 (53%), Positives = 62/99 (62%), Gaps = 9/99 (9%)

Query: 1030 YPWMR--KLHISHDNIGG-------PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIE 1080
            +PWM+  K H       G        E KR RTAYTR Q LELEKEF FN+Y++R RR+E
Sbjct: 119  FPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 178

Query: 1081 IAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGG 1119
            +A  L L+ER IKIWFQNRRMKWKK+   K     A GG
Sbjct: 179  LAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGG 217



 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 52/103 (50%), Positives = 62/103 (60%), Gaps = 20/103 (19%)

Query: 272 EGALHGAAEANFRI---YPWMRSSGP-----------------DRKRGRQTYTRYQTLEL 311
           EGA  G  E   R+   +PWM+S+                   + KR R  YTR Q LEL
Sbjct: 102 EGAEPGVLEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLEL 161

Query: 312 EKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 354
           EKEF FN+Y++R RR+E+A  L LTER IKIWFQNRRMKWKKE
Sbjct: 162 EKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKE 204



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 57/153 (37%), Positives = 68/153 (44%), Gaps = 31/153 (20%)

Query: 626 YPWMQRMNS------CAGAVYGSH---XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIE 676
           +PWM+   +       AG  Y +                 LELEKEF FN+Y++R RR+E
Sbjct: 119 FPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 178

Query: 677 IANALCLTERQIKIWFQNRRMKWKKE--NKLINSTQPSG-------EDSEAKAGEE---- 723
           +A  L LTER IKIWFQNRRMKWKKE   K    T   G       +D    +GEE    
Sbjct: 179 LAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLAL 238

Query: 724 -----PG----PTRWVQGEPSDLGPGWLEEPDP 747
                PG    P   V      L PG    P P
Sbjct: 239 PPPPPPGGAVPPAAPVAAREGRLPPGLSASPQP 271



>gi|123286|sp|P28356|HXD9_HUMAN   Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2)
          Length = 342

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 58/144 (40%), Positives = 75/144 (52%), Gaps = 9/144 (6%)

Query: 221 YNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAE 280
           ++ NS L +       G G  A       +   + P  CSD     C   +E   H   +
Sbjct: 197 FSCNSFLQEKAAGGDGGNGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQ 256

Query: 281 ANFRIYP------WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 334
              ++ P      W+ +    +KR    YT+YQTLELEKEF FN YLTR RR E+A  L 
Sbjct: 257 QQ-QLDPNNPEANWIHARSTRKKRC--PYTKYQTLELEKEFLFNMYLTRDRRYEVARILN 313

Query: 335 LTERQIKIWFQNRRMKWKKEHKDE 358
           LTERQ+KIWFQNRRMK KK  K++
Sbjct: 314 LTERQVKIWFQNRRMKMKKMSKEK 337



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 42/62 (67%), Positives = 49/62 (79%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  YT+YQTLELEKEF FN YLTR RR E+A  L L+ERQ+KIWFQNRRMK KK +K
Sbjct: 276  RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSK 335

Query: 1109 LK 1110
             K
Sbjct: 336  EK 337



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 5/181 (2%)

Query: 526 PFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASY--EYGASCFYSDKDLSGASPSGSG 583
           P PA+  +++    T  S    +   SV   ++ S   E+  + F  +K   G   +G G
Sbjct: 158 PAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAGGDGGNGPG 217

Query: 584 KQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSH 643
              G       S E     D     G +L +E  +++++ P    +   N  A  ++   
Sbjct: 218 AGIGAATGTGGSSEPSACSDHPI-PGCSLKEE--EKQHSQPQQQQLDPNNPEANWIHARS 274

Query: 644 XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 703
                        LELEKEF FN YLTR RR E+A  L LTERQ+KIWFQNRRMK KK +
Sbjct: 275 TRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMS 334

Query: 704 K 704
           K
Sbjct: 335 K 335



>gi|20141537|sp|P31274|HXC9_HUMAN   Homeobox protein Hox-C9 (Hox-3B)
          Length = 260

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 51/111 (45%), Positives = 68/111 (61%), Gaps = 6/111 (5%)

Query: 253 QNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELE 312
           Q +P   +D   G+  K ++  L    + +  +  W+ +    +KR    YT+YQTLELE
Sbjct: 155 QTLPSPEADALAGSKHKEEKADL----DPSNPVANWIHARSTRKKRC--PYTKYQTLELE 208

Query: 313 KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQ 363
           KEF FN YLTR RR E+A  L LTERQ+KIWFQNRRMK KK +K++    Q
Sbjct: 209 KEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQ 259



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 43/63 (68%), Positives = 50/63 (79%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  YT+YQTLELEKEF FN YLTR RR E+A  L L+ERQ+KIWFQNRRMK KK NK
Sbjct: 193  RKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNK 252

Query: 1109 LKS 1111
             K+
Sbjct: 253  EKT 255



 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 51/121 (42%), Positives = 64/121 (52%), Gaps = 18/121 (14%)

Query: 588 PGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQ----RMNSCAGAVYGSH 643
           PG+    +P+    P++ +  G    +E AD   ++PV  W+     R   C    Y + 
Sbjct: 146 PGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQT- 204

Query: 644 XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 703
                        LELEKEF FN YLTR RR E+A  L LTERQ+KIWFQNRRMK KK N
Sbjct: 205 -------------LELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMN 251

Query: 704 K 704
           K
Sbjct: 252 K 252



>gi|123270|sp|P14652|HXB2_HUMAN   Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8)
          Length = 356

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 49/93 (52%), Positives = 58/93 (62%), Gaps = 4/93 (4%)

Query: 291 SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           + G   +R R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK
Sbjct: 138 AGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK 197

Query: 351 WKKEHKDEAQAHQPPLLEGNVPELAADLWRPRE 383
               HK + Q  +PP  E   P    D+  P E
Sbjct: 198 ----HKRQTQHREPPDGEPACPGALEDICDPAE 226



 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 42/65 (64%), Positives = 50/65 (76%)

Query: 1044 GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            GG   +R RTAYT  Q LELEKEFHFN+YL R RR+EIA  L L+ERQ+K+WFQNRRMK 
Sbjct: 139  GGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH 198

Query: 1104 KKDNK 1108
            K+  +
Sbjct: 199  KRQTQ 203



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 37/58 (63%), Positives = 45/58 (77%), Gaps = 2/58 (3%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGE 714
           LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK K++ +  +   P GE
Sbjct: 156 LELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ--HREPPDGE 211



>gi|6166219|sp|P31269|HXA9_HUMAN   Homeobox protein Hox-A9 (Hox-1G)
          Length = 272

 Score = 89.4 bits (220), Expect = 7e-18
 Identities = 45/73 (61%), Positives = 54/73 (73%), Gaps = 2/73 (2%)

Query: 288 WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           W+ +    +KR    YT++QTLELEKEF FN YLTR RR E+A  L LTERQ+KIWFQNR
Sbjct: 200 WLHARSTRKKRC--PYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNR 257

Query: 348 RMKWKKEHKDEAQ 360
           RMK KK +KD A+
Sbjct: 258 RMKMKKINKDRAK 270



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 41/60 (68%), Positives = 48/60 (80%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  YT++QTLELEKEF FN YLTR RR E+A  L L+ERQ+KIWFQNRRMK KK NK
Sbjct: 207  RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINK 266



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 49/118 (41%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 590 DYLHFSPEQQYKPDSSSG---QGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXX 646
           DY   SP    +   S G   +  A ++ G D+    P        N  A  ++      
Sbjct: 156 DYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDP-------NNPAANWLHARSTRK 208

Query: 647 XXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
                     LELEKEF FN YLTR RR E+A  L LTERQ+KIWFQNRRMK KK NK
Sbjct: 209 KRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINK 266



>gi|6016292|sp|O43364|HXA2_HUMAN   Homeobox protein Hox-A2
          Length = 376

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 45/75 (60%), Positives = 55/75 (73%), Gaps = 2/75 (2%)

Query: 1036 LHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIW 1095
            L I+  + GG   +R RTAYT  Q LELEKEFHFN+YL R RR+EIA  L L+ERQ+K+W
Sbjct: 133  LEIADGSGGG--SRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 190

Query: 1096 FQNRRMKWKKDNKLK 1110
            FQNRRMK K+  + K
Sbjct: 191  FQNRRMKHKRQTQCK 205



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 46/83 (55%), Positives = 53/83 (63%), Gaps = 4/83 (4%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           SG   +R R  YT  Q LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK 
Sbjct: 139 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMK- 197

Query: 352 KKEHKDEAQAHQPPLLEGNVPEL 374
              HK + Q  +    EG    L
Sbjct: 198 ---HKRQTQCKENQNSEGKCKSL 217



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 45/80 (56%), Positives = 52/80 (65%), Gaps = 5/80 (6%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWK-----KENKLINSTQP 711
           LELEKEFHFN+YL R RR+EIA  L LTERQ+K+WFQNRRMK K     KEN+       
Sbjct: 156 LELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCK 215

Query: 712 SGEDSEAKAGEEPGPTRWVQ 731
           S EDSE    +E   T + Q
Sbjct: 216 SLEDSEKVEEDEEEKTLFEQ 235



>gi|20141507|sp|P17482|HXB9_HUMAN   Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5)
          Length = 250

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 43/60 (71%), Positives = 48/60 (80%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  YT+YQTLELEKEF FN YLTR RR E+A  L LSERQ+KIWFQNRRMK KK NK
Sbjct: 186  RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 43/73 (58%), Positives = 54/73 (73%), Gaps = 2/73 (2%)

Query: 288 WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           W+ +    +KR    YT+YQTLELEKEF FN YLTR RR E+A  L L+ERQ+KIWFQNR
Sbjct: 179 WLHARSSRKKRC--PYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNR 236

Query: 348 RMKWKKEHKDEAQ 360
           RMK KK +K++ +
Sbjct: 237 RMKMKKMNKEQGK 249



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 36/48 (75%), Positives = 39/48 (81%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELEKEF FN YLTR RR E+A  L L+ERQ+KIWFQNRRMK KK NK
Sbjct: 198 LELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245



>gi|13124743|sp|P31260|HXA10_HUMAN   Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL)
          Length = 393

 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 52/124 (41%), Positives = 75/124 (60%), Gaps = 8/124 (6%)

Query: 234 SGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYPWMRSSG 293
           SG G   D   +   ++ ++  P   S+ +K + +K   G   G   AN     W+ +  
Sbjct: 265 SGGGSQGDEEAHASSSAAEELSPAP-SESSKASPEKDSLGNSKGENAAN-----WLTAKS 318

Query: 294 PDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
             +KR    YT++QTLELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNRRMK KK
Sbjct: 319 GRKKRC--PYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 376

Query: 354 EHKD 357
            +++
Sbjct: 377 MNRE 380



 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 39/61 (63%), Positives = 51/61 (83%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN 1107
            G++ R  YT++QTLELEKEF FN YLTR RR+EI+ ++ L++RQ+KIWFQNRRMK KK N
Sbjct: 319  GRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMN 378

Query: 1108 K 1108
            +
Sbjct: 379  R 379



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 34/48 (70%), Positives = 41/48 (85%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNRRMK KK N+
Sbjct: 332 LELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNR 379



>gi|1345720|sp|P47902|CDX1_HUMAN   Homeobox protein CDX-1 (Caudal-type homeobox protein 1)
          Length = 265

 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 47/91 (51%), Positives = 58/91 (63%), Gaps = 11/91 (12%)

Query: 286 YPWMR---------SSGPDRKRG--RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 334
           Y WMR          SG  R +   R  YT +Q LELEKEFH++RY+T RR+ E+A  L 
Sbjct: 133 YEWMRRSVAAGGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLG 192

Query: 335 LTERQIKIWFQNRRMKWKKEHKDEAQAHQPP 365
           LTERQ+KIWFQNRR K +K +K + Q  QPP
Sbjct: 193 LTERQVKIWFQNRRAKERKVNKKKQQQQQPP 223



 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 45/86 (52%), Positives = 57/86 (66%), Gaps = 7/86 (8%)

Query: 1030 YPWMRKLHISHDNIGGPEGK-----RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 1084
            Y WMR+   +    GG  GK     + R  YT +Q LELEKEFH++RY+T RR+ E+A  
Sbjct: 133  YEWMRRSVAAGG--GGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAAN 190

Query: 1085 LCLSERQIKIWFQNRRMKWKKDNKLK 1110
            L L+ERQ+KIWFQNRR K +K NK K
Sbjct: 191  LGLTERQVKIWFQNRRAKERKVNKKK 216



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 64/190 (33%), Positives = 80/190 (42%), Gaps = 15/190 (7%)

Query: 528 PASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRG 587
           PA+YG  + P      P F   S+ V         +GA       D + A   G      
Sbjct: 27  PANYGPPAPPPAPPQYPDFSSYSH-VEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAA 85

Query: 588 PGDYLHFSPEQQYKP---DSSSGQGKALHDEGADRKYTSP------VYPWMQRMNSCAGA 638
               L F P   + P       G G      G     +SP       Y WM+R +  AG 
Sbjct: 86  SPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYEWMRR-SVAAGG 144

Query: 639 VYGSHXXXXXXXXXXXXX----LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQN 694
             GS                  LELEKEFH++RY+T RR+ E+A  L LTERQ+KIWFQN
Sbjct: 145 GGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQN 204

Query: 695 RRMKWKKENK 704
           RR K +K NK
Sbjct: 205 RRAKERKVNK 214



>gi|20141612|sp|Q9NYD6|HXC10_HUMAN   Homeobox protein Hox-C10
          Length = 342

 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 39/61 (63%), Positives = 50/61 (81%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN 1107
            G++ R  YT++QTLELEKEF FN YLTR RR+EI+  + L++RQ+KIWFQNRRMK KK N
Sbjct: 268  GRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMN 327

Query: 1108 K 1108
            +
Sbjct: 328  R 328



 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 40/70 (57%), Positives = 53/70 (75%), Gaps = 2/70 (2%)

Query: 288 WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           W+ +    +KR    YT++QTLELEKEF FN YLTR RR+EI+  + LT+RQ+KIWFQNR
Sbjct: 262 WLTAKSGRKKRC--PYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNR 319

Query: 348 RMKWKKEHKD 357
           RMK KK +++
Sbjct: 320 RMKLKKMNRE 329



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 34/48 (70%), Positives = 40/48 (83%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELEKEF FN YLTR RR+EI+  + LT+RQ+KIWFQNRRMK KK N+
Sbjct: 281 LELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR 328



>gi|123289|sp|P28358|HXD10_HUMAN   Homeobox protein Hox-D10 (Hox-4D) (Hox-4E)
          Length = 340

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 39/69 (56%), Positives = 56/69 (81%), Gaps = 3/69 (4%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK-- 1105
            G++ R  YT++QTLELEKEF FN YLTR RR+EI+ ++ L++RQ+KIWFQNRRMK KK  
Sbjct: 266  GRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMS 325

Query: 1106 -DNKLKSMS 1113
             +N+++ ++
Sbjct: 326  RENRIRELT 334



 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 40/70 (57%), Positives = 53/70 (75%), Gaps = 2/70 (2%)

Query: 288 WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           W+ +    +KR    YT++QTLELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNR
Sbjct: 260 WLTAKSGRKKRC--PYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNR 317

Query: 348 RMKWKKEHKD 357
           RMK KK  ++
Sbjct: 318 RMKLKKMSRE 327



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 33/48 (68%), Positives = 41/48 (85%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNRRMK KK ++
Sbjct: 279 LELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR 326



>gi|27923786|sp|Q9H4S2|GSHI_HUMAN   Homeobox protein GSH-1
          Length = 264

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 44/75 (58%), Positives = 52/75 (69%)

Query: 1046 PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            P  KR RTA+T  Q LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK
Sbjct: 145  PSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 204

Query: 1106 DNKLKSMSMAAAGGA 1120
            + K  +      GGA
Sbjct: 205  EGKGSNHRGGGGGGA 219



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 39/63 (61%), Positives = 46/63 (73%)

Query: 294 PDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           P  KR R  +T  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KK
Sbjct: 145 PSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 204

Query: 354 EHK 356
           E K
Sbjct: 205 EGK 207



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 33/48 (68%), Positives = 39/48 (81%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KKE K
Sbjct: 160 LELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207



>gi|20138327|sp|Q9BZM3|GSH2_HUMAN   Homeobox protein GSH-2
          Length = 304

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 42/63 (66%), Positives = 49/63 (77%)

Query: 1046 PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            P GKR RTA+T  Q LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK
Sbjct: 200  PNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 259

Query: 1106 DNK 1108
            + K
Sbjct: 260  EGK 262



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 40/66 (60%), Positives = 48/66 (72%)

Query: 291 SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           S  P+ KR R  +T  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K
Sbjct: 197 SQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVK 256

Query: 351 WKKEHK 356
            KKE K
Sbjct: 257 HKKEGK 262



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 33/48 (68%), Positives = 39/48 (81%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KKE K
Sbjct: 215 LELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 262



>gi|123271|sp|P14653|HXB1_HUMAN   Homeobox protein Hox-B1 (Hox-2I)
          Length = 301

 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 41/68 (60%), Positives = 49/68 (72%), Gaps = 2/68 (2%)

Query: 1038 ISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQ 1097
            +S   +G P G   RT +T  Q  ELEKEFHFN+YL+R RR+EIA  L L+E Q+KIWFQ
Sbjct: 195  VSEPGLGSPSG--LRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQ 252

Query: 1098 NRRMKWKK 1105
            NRRMK KK
Sbjct: 253  NRRMKQKK 260



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 42/78 (53%), Positives = 50/78 (64%), Gaps = 2/78 (2%)

Query: 300 RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEA 359
           R  +T  Q  ELEKEFHFN+YL+R RR+EIA  L L E Q+KIWFQNRRMK KK  ++  
Sbjct: 207 RTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGG 266

Query: 360 QAHQPPLLEGNVPELAAD 377
           +   PP   G   E A D
Sbjct: 267 RV--PPAPPGCPKEAAGD 282



 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 39/79 (49%), Positives = 47/79 (59%), Gaps = 10/79 (12%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELEKEFHFN+YL+R RR+EIA  L L E Q+KIWFQNRRMK KK  +      P+     
Sbjct: 217 ELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRVPPA----- 271

Query: 718 AKAGEEPGPTRWVQGEPSD 736
                 PG  +   G+ SD
Sbjct: 272 -----PPGCPKEAAGDASD 285



>gi|6166216|sp|P49639|HXA1_HUMAN   Homeobox protein Hox-A1 (Hox-1F)
          Length = 335

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 41/71 (57%), Positives = 47/71 (66%)

Query: 300 RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEA 359
           R  +T  Q  ELEKEFHFN+YLTR RR+EIA +L L E Q+KIWFQNRRMK KK  K+  
Sbjct: 233 RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGL 292

Query: 360 QAHQPPLLEGN 370
               P    GN
Sbjct: 293 LPISPATPPGN 303



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 39/57 (68%), Positives = 45/57 (78%)

Query: 1052 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            RT +T  Q  ELEKEFHFN+YLTR RR+EIA +L L+E Q+KIWFQNRRMK KK  K
Sbjct: 233  RTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREK 289



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 41/70 (58%), Positives = 48/70 (68%), Gaps = 4/70 (5%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK----LINSTQPSG 713
           ELEKEFHFN+YLTR RR+EIA +L L E Q+KIWFQNRRMK KK  K     I+   P G
Sbjct: 243 ELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPG 302

Query: 714 EDSEAKAGEE 723
            D +A+   E
Sbjct: 303 NDEKAEESSE 312



>gi|45644931|sp|P50219|HLXB9_HUMAN   Homeobox protein HB9
          Length = 403

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 37/69 (53%), Positives = 49/69 (71%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RTA+T  Q LELE +F  N+YL+R +R E+A +L L+E Q+KIWFQNRRMKWK+  K
Sbjct: 244  RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 303

Query: 1109 LKSMSMAAA 1117
             K  +   A
Sbjct: 304  AKEQAAQEA 312



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 37/67 (55%), Positives = 48/67 (71%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +R R  +T  Q LELE +F  N+YL+R +R E+A +L LTE Q+KIWFQNRRMKWK+  K
Sbjct: 244 RRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK 303

Query: 357 DEAQAHQ 363
            + QA Q
Sbjct: 304 AKEQAAQ 310



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 43/103 (41%), Positives = 54/103 (52%), Gaps = 12/103 (11%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 716
           LELE +F  N+YL+R +R E+A +L LTE Q+KIWFQNRRMKWK+  K         E  
Sbjct: 256 LELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQ 315

Query: 717 EAKAG-------EEPGPTRWV-QGEPSDLGPGW----LEEPDP 747
           +   G       EEPG    +    P D G G     L + DP
Sbjct: 316 KGGGGGAGKGGAEEPGAEELLGPPAPGDKGSGXRLRDLRDSDP 358



>gi|20141282|sp|Q99626|CDX2_HUMAN   Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3)
          Length = 313

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 44/83 (53%), Positives = 55/83 (66%), Gaps = 6/83 (7%)

Query: 1032 WMRKLHISHDNIGGPEGKRA----RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL 1087
            WMRK   +  ++G     R     R  YT +Q LELEKEFH++RY+T RR+ E+A  L L
Sbjct: 168  WMRKP--AQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGL 225

Query: 1088 SERQIKIWFQNRRMKWKKDNKLK 1110
            SERQ+KIWFQNRR K +K NK K
Sbjct: 226  SERQVKIWFQNRRAKERKINKKK 248



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 46/103 (44%), Positives = 60/103 (58%), Gaps = 10/103 (9%)

Query: 300 RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK--- 356
           R  YT +Q LELEKEFH++RY+T RR+ E+A  L L+ERQ+KIWFQNRR K +K +K   
Sbjct: 190 RVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKINKKKL 249

Query: 357 DEAQAHQPPLLEGNVPELAADLWRPREAQKEVARHTVFPASPL 399
            + Q  QPP      P+       P + Q    R    P SP+
Sbjct: 250 QQQQQQQPPQPPPPPPQ-------PPQPQPGPLRSVPEPLSPV 285



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 71/239 (29%), Positives = 96/239 (40%), Gaps = 45/239 (18%)

Query: 527 FPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQR 586
           +PA+YGA    D    +P       +  A N  ++            L+G SP+ +    
Sbjct: 65  WPAAYGAPLREDWNGYAP-----GGAAAAANAVAH-----------GLNGGSPAAAMGYS 108

Query: 587 GPGDYL------HFSPEQQYKPDSSSGQGKALHDEGADRKYTSP---VYPWMQRMNSC-- 635
            P DY       H        P  +SG  + L+        T+    + P  QR N C  
Sbjct: 109 SPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEW 168

Query: 636 ----AGAVYGSHXXXXXXXX-----XXXXXLELEKEFHFNRYLTRRRRIEIANALCLTER 686
               A    GS                   LELEKEFH++RY+T RR+ E+A  L L+ER
Sbjct: 169 MRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSER 228

Query: 687 QIKIWFQNRRMKWKKENKLINSTQPSGEDSE------AKAGEEPGPTRWVQGEPSDLGP 739
           Q+KIWFQNRR K +K NK     Q   +  +           +PGP R V   P  L P
Sbjct: 229 QVKIWFQNRRAKERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSV---PEPLSP 284



>gi|17378648|sp|Q9GZZ0|HXD1_HUMAN   Homeobox protein Hox-D1
          Length = 328

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 45/106 (42%), Positives = 58/106 (54%), Gaps = 14/106 (13%)

Query: 281 ANFRIYPWMRSSGPDRKRG--------------RQTYTRYQTLELEKEFHFNRYLTRRRR 326
           A F  + WM+      K+G              R  ++  Q  ELEKEFHFN+YLTR RR
Sbjct: 200 AAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARR 259

Query: 327 IEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQPPLLEGNVP 372
           IEIA+ L L + Q+KIWFQNRRMK KK  ++   A   P+    +P
Sbjct: 260 IEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVAPLQLP 305



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 37/54 (68%), Positives = 44/54 (81%)

Query: 1052 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            RT ++  Q  ELEKEFHFN+YLTR RRIEIA+ L L++ Q+KIWFQNRRMK KK
Sbjct: 233  RTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKK 286



 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 35/47 (74%), Positives = 39/47 (82%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEKEFHFN+YLTR RRIEIAN L L + Q+KIWFQNRRMK KK  +
Sbjct: 243 ELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKRER 289



>gi|1709078|sp|P50221|MEOX1_HUMAN   Homeobox protein MOX-1 (Mesenchyme homeobox 1)
          Length = 254

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 41/71 (57%), Positives = 51/71 (71%), Gaps = 4/71 (5%)

Query: 1039 SHDNIGGPEG----KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKI 1094
            + +N G PEG    ++ RTA+T+ Q  ELE EF  + YLTR RR EIA  L LSERQ+K+
Sbjct: 158  NQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKV 217

Query: 1095 WFQNRRMKWKK 1105
            WFQNRRMKWK+
Sbjct: 218  WFQNRRMKWKR 228



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 38/77 (49%), Positives = 48/77 (62%), Gaps = 5/77 (6%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           ++ R  +T+ Q  ELE EF  + YLTR RR EIA  L L+ERQ+K+WFQNRRMKWK+   
Sbjct: 172 RKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKR--- 228

Query: 357 DEAQAHQPPLLEGNVPE 373
              +  QP    G  PE
Sbjct: 229 --VKGGQPISPNGQDPE 243



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 35/60 (58%), Positives = 42/60 (70%), Gaps = 1/60 (1%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELE EF  + YLTR RR EIA  L L+ERQ+K+WFQNRRMKWK+  K      P+G+D E
Sbjct: 185 ELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV-KGGQPISPNGQDPE 243



>gi|12230077|sp|Q14549|GBX1_HUMAN   Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox
            protein 1)
          Length = 139

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 38/61 (62%), Positives = 46/61 (75%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G + +R RTA+T  Q LELEKEFH  +YL+   R +IAHAL LSE Q+KIWFQNRR KWK
Sbjct: 34   GGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWK 93

Query: 1105 K 1105
            +
Sbjct: 94   R 94



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 39/82 (47%), Positives = 52/82 (63%)

Query: 272 EGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAH 331
           +G+L   AE    +   + + G   +R R  +T  Q LELEKEFH  +YL+   R +IAH
Sbjct: 13  KGSLGTGAEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAH 72

Query: 332 ALCLTERQIKIWFQNRRMKWKK 353
           AL L+E Q+KIWFQNRR KWK+
Sbjct: 73  ALKLSEVQVKIWFQNRRAKWKR 94



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 34/58 (58%), Positives = 42/58 (72%), Gaps = 1/58 (1%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGE 714
           LELEKEFH  +YL+   R +IA+AL L+E Q+KIWFQNRR KWK+  K  N +  SGE
Sbjct: 50  LELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR-IKAGNVSSRSGE 106



>gi|12644308|sp|P52951|GBX2_HUMAN   Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox
            protein 2)
          Length = 348

 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 37/59 (62%), Positives = 45/59 (76%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            + +R RTA+T  Q LELEKEFH  +YL+   R +IAHAL LSE Q+KIWFQNRR KWK+
Sbjct: 246  KNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR 304



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 37/63 (58%), Positives = 47/63 (74%), Gaps = 1/63 (1%)

Query: 291 SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           S+G +R+R R  +T  Q LELEKEFH  +YL+   R +IAHAL L+E Q+KIWFQNRR K
Sbjct: 243 STGKNRRR-RTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAK 301

Query: 351 WKK 353
           WK+
Sbjct: 302 WKR 304



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 34/60 (56%), Positives = 43/60 (71%), Gaps = 1/60 (1%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 716
           LELEKEFH  +YL+   R +IA+AL L+E Q+KIWFQNRR KWK+  K  N+   +GE S
Sbjct: 260 LELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRV-KAGNANSKTGEPS 318



>gi|3023467|sp|O14627|CDX4_HUMAN   Homeobox protein CDX-4 (Caudal-type homeobox protein 4)
          Length = 284

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 45/91 (49%), Positives = 55/91 (60%), Gaps = 2/91 (2%)

Query: 1030 YPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSE 1089
            Y WMRK           E  + R  YT +Q LELEKEFH NRY+T +R+ E+A  L LSE
Sbjct: 157  YAWMRKTVQVTGKTRTKE--KYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSE 214

Query: 1090 RQIKIWFQNRRMKWKKDNKLKSMSMAAAGGA 1120
            RQ+KIWFQNRR K +K  K K      +GG+
Sbjct: 215  RQVKIWFQNRRAKERKMIKKKISQFENSGGS 245



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 47/99 (47%), Positives = 62/99 (62%), Gaps = 8/99 (8%)

Query: 263 AKGACDKTDEGALHGAAEANFRI--YPWMRSS----GPDR--KRGRQTYTRYQTLELEKE 314
           A G+   TD GA   ++ +  R   Y WMR +    G  R  ++ R  YT +Q LELEKE
Sbjct: 132 AGGSLVPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKE 191

Query: 315 FHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           FH NRY+T +R+ E+A  L L+ERQ+KIWFQNRR K +K
Sbjct: 192 FHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERK 230



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 60/183 (32%), Positives = 75/183 (40%), Gaps = 41/183 (22%)

Query: 569 YSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPW 628
           +   D S   P G G     G  L         P + +G  KA       R   SP Y W
Sbjct: 108 FCSTDYSNLGPVGGGTS---GSSLPGQAGGSLVP-TDAGAAKA---SSPSRSRHSP-YAW 159

Query: 629 MQRMNSCAG---------AVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIAN 679
           M++     G          VY  H             LELEKEFH NRY+T +R+ E+A 
Sbjct: 160 MRKTVQVTGKTRTKEKYRVVYTDHQR-----------LELEKEFHCNRYITIQRKSELAV 208

Query: 680 ALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEEPGPTRWVQGEPSDLGP 739
            L L+ERQ+KIWFQNRR    KE K+I       E+S             VQ +   + P
Sbjct: 209 NLGLSERQVKIWFQNRR---AKERKMIKKKISQFENSGGS----------VQSDSDSISP 255

Query: 740 GWL 742
           G L
Sbjct: 256 GEL 258



>gi|399982|sp|P31314|TLX1_HUMAN   T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (TCL-3
           proto-oncogene)
          Length = 330

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 53/170 (31%), Positives = 75/170 (44%), Gaps = 25/170 (14%)

Query: 219 GLYNVNSPLYQSPFASGYGLGADAYGNLPCASY-----DQNIPGLCSD---LAKGACDKT 270
           G YNVN  L   P   G G  +   G L  A        + + G  +    LA G     
Sbjct: 99  GSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVP 158

Query: 271 DEGALHGAAEANFRIYPWMRSSG-----------------PDRKRGRQTYTRYQTLELEK 313
              A+ G        +PWM S+                  P +K+ R ++TR Q  ELEK
Sbjct: 159 SVPAMPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEK 218

Query: 314 EFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQ 363
            FH  +YL    R  +A AL +T+ Q+K WFQNRR KW+++  +E +A +
Sbjct: 219 RFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAER 268



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 9/85 (10%)

Query: 1030 YPWMRK-LHISHDNIGG--------PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIE 1080
            +PWM      + D   G        P+ K+ RT++TR Q  ELEK FH  +YL    R  
Sbjct: 174  FPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAA 233

Query: 1081 IAHALCLSERQIKIWFQNRRMKWKK 1105
            +A AL +++ Q+K WFQNRR KW++
Sbjct: 234  LAKALKMTDAQVKTWFQNRRTKWRR 258



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 23/45 (51%), Positives = 31/45 (68%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELEK FH  +YL    R  +A AL +T+ Q+K WFQNRR KW+++
Sbjct: 215 ELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQ 259



>gi|13124744|sp|P31270|HXA11_HUMAN   Homeobox protein Hox-A11 (Hox-1I)
          Length = 313

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 38/78 (48%), Positives = 55/78 (70%), Gaps = 1/78 (1%)

Query: 291 SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           SSG   ++ R  YT+YQ  ELE+EF F+ Y+ + +R++++  L LT+RQ+KIWFQNRRMK
Sbjct: 236 SSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMK 295

Query: 351 WKKEHKDEAQAHQP-PLL 367
            KK ++D  Q +   PLL
Sbjct: 296 EKKINRDRLQYYSANPLL 313



 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 35/73 (47%), Positives = 51/73 (69%), Gaps = 3/73 (4%)

Query: 1039 SHDNIGGPEGKRARTA---YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIW 1095
            + D  GG  G+R R     YT+YQ  ELE+EF F+ Y+ + +R++++  L L++RQ+KIW
Sbjct: 229  TEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIW 288

Query: 1096 FQNRRMKWKKDNK 1108
            FQNRRMK KK N+
Sbjct: 289  FQNRRMKEKKINR 301



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 26/47 (55%), Positives = 38/47 (80%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE+EF F+ Y+ + +R++++  L LT+RQ+KIWFQNRRMK KK N+
Sbjct: 255 ELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR 301



>gi|12644203|sp|P31277|HXD11_HUMAN   Homeobox protein Hox-D11 (Hox-4F)
          Length = 338

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 35/68 (51%), Positives = 50/68 (73%), Gaps = 1/68 (1%)

Query: 294 PDRKRGRQT-YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 352
           P R R ++  YT+YQ  ELE+EF FN Y+ + +R++++  L LT+RQ+KIWFQNRRMK K
Sbjct: 263 PQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEK 322

Query: 353 KEHKDEAQ 360
           K ++D  Q
Sbjct: 323 KLNRDRLQ 330



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 32/70 (45%), Positives = 48/70 (68%)

Query: 1039 SHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 1098
            S   +     ++ R  YT+YQ  ELE+EF FN Y+ + +R++++  L L++RQ+KIWFQN
Sbjct: 257  SSSAVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQN 316

Query: 1099 RRMKWKKDNK 1108
            RRMK KK N+
Sbjct: 317  RRMKEKKLNR 326



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 603 DSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKE 662
           + S G G+    E    K +S V P   R   C    Y                 ELE+E
Sbjct: 239 EGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIR--------------ELERE 284

Query: 663 FHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           F FN Y+ + +R++++  L LT+RQ+KIWFQNRRMK KK N+
Sbjct: 285 FFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNR 326



>gi|3287858|sp|O43248|HXC11_HUMAN   Homeobox protein Hox-C11
          Length = 304

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 57/168 (33%), Positives = 83/168 (49%), Gaps = 25/168 (14%)

Query: 215 STVPGLY---NVNSPLYQSP---FASGYGLGADAYGNLPC-----ASYDQNIP---GLCS 260
           +T  G Y   N NS L Q+    F + Y  G D     PC     A  +   P   GL S
Sbjct: 132 ATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLAS 191

Query: 261 DLAKGACDKTDE--------GALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELE 312
               GA  + +E        G+ H  A+   +       + P  ++ R  Y+++Q  ELE
Sbjct: 192 RAEAGAEAEAEEENTNPSSSGSAHSVAKEPAK---GAAPNAPRTRKKRCPYSKFQIRELE 248

Query: 313 KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQ 360
           +EF FN Y+ + +R++++  L LT+RQ+KIWFQNRRMK KK  +D  Q
Sbjct: 249 REFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRDRLQ 296



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 29/60 (48%), Positives = 45/60 (75%)

Query: 1046 PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            P  ++ R  Y+++Q  ELE+EF FN Y+ + +R++++  L L++RQ+KIWFQNRRMK KK
Sbjct: 230  PRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 289



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 60/207 (28%), Positives = 88/207 (42%), Gaps = 34/207 (16%)

Query: 510 QECLLGSSEAGYDALRPFPASYGASSLPDKTYTSPC-FYQQSNSVLACNRASYEYGASCF 568
           +ECL  S+    + L     SYG    P   + +P  FY   N      +A   +  + +
Sbjct: 102 RECLPPSTVT--EILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAY 159

Query: 569 YSDKDLSGASP-SGSGKQRG-----PGDYL--------HFSPEQQYKPDSSSGQGKALHD 614
               D     P SG G+ +G     P   L            E++    SSSG   ++  
Sbjct: 160 CGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAK 219

Query: 615 EGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRR 674
           E A  K  +P  P   R   C  + +                 ELE+EF FN Y+ + +R
Sbjct: 220 EPA--KGAAPNAP-RTRKKRCPYSKFQIR--------------ELEREFFFNVYINKEKR 262

Query: 675 IEIANALCLTERQIKIWFQNRRMKWKK 701
           ++++  L LT+RQ+KIWFQNRRMK KK
Sbjct: 263 LQLSRMLNLTDRQVKIWFQNRRMKEKK 289



>gi|1709079|sp|P50222|MEOX2_HUMAN   Homeobox protein MOX-2 (Mesenchyme homeobox 2) (Growth
            arrest-specific homeobox)
          Length = 303

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 35/57 (61%), Positives = 44/57 (77%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ RTA+T+ Q  ELE EF  + YLTR RR EIA  L L+ERQ+K+WFQNRRMKWK+
Sbjct: 187  RKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKR 243



 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 34/57 (59%), Positives = 42/57 (73%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           ++ R  +T+ Q  ELE EF  + YLTR RR EIA  L LTERQ+K+WFQNRRMKWK+
Sbjct: 187 RKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKVWFQNRRMKWKR 243



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 45/132 (34%), Positives = 59/132 (44%), Gaps = 17/132 (12%)

Query: 570 SDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWM 629
           +   L  ++P+G+     PGDY   +         S G+ K+   +  +  Y S V    
Sbjct: 129 NSSSLGSSTPTGAAC--APGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEV---- 182

Query: 630 QRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIK 689
                       S               ELE EF  + YLTR RR EIA  L LTERQ+K
Sbjct: 183 -----------NSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVK 231

Query: 690 IWFQNRRMKWKK 701
           +WFQNRRMKWK+
Sbjct: 232 VWFQNRRMKWKR 243



>gi|23831508|sp|O43711|TLX3_HUMAN   T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2)
          Length = 291

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 31/76 (40%), Positives = 49/76 (64%)

Query: 286 YPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +P+   + P RK+ R +++R Q  ELEK FH  +YL    R  +A +L +T+ Q+K WFQ
Sbjct: 156 HPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQ 215

Query: 346 NRRMKWKKEHKDEAQA 361
           NRR KW+++  +E +A
Sbjct: 216 NRRTKWRRQTAEEREA 231



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 29/72 (40%), Positives = 46/72 (63%)

Query: 1034 RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK 1093
            R++   + N   P+ K+ RT+++R Q  ELEK FH  +YL    R  +A +L +++ Q+K
Sbjct: 152  RRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVK 211

Query: 1094 IWFQNRRMKWKK 1105
             WFQNRR KW++
Sbjct: 212  TWFQNRRTKWRR 223



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 22/45 (48%), Positives = 31/45 (68%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELEK FH  +YL    R  +A +L +T+ Q+K WFQNRR KW+++
Sbjct: 180 ELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224



>gi|20532396|sp|O43763|TLX2_HUMAN   T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1)
           (Neural crest homeobox protein)
          Length = 284

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 31/78 (39%), Positives = 50/78 (64%)

Query: 286 YPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +P+   + P RK+ R +++R Q LELE+ F   +YL    R  +A AL +T+ Q+K WFQ
Sbjct: 147 HPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQ 206

Query: 346 NRRMKWKKEHKDEAQAHQ 363
           NRR KW+++  +E +A +
Sbjct: 207 NRRTKWRRQTAEEREAER 224



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 29/72 (40%), Positives = 46/72 (63%)

Query: 1034 RKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIK 1093
            R++   + N   P+ K+ RT+++R Q LELE+ F   +YL    R  +A AL +++ Q+K
Sbjct: 143  RRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMTDAQVK 202

Query: 1094 IWFQNRRMKWKK 1105
             WFQNRR KW++
Sbjct: 203  TWFQNRRTKWRR 214



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 22/46 (47%), Positives = 31/46 (67%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           LELE+ F   +YL    R  +A AL +T+ Q+K WFQNRR KW+++
Sbjct: 170 LELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQ 215



>gi|14194481|sp|Q9HBU1|BARX1_HUMAN   Homeobox protein BarH-like 1
          Length = 225

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 30/59 (50%), Positives = 43/59 (72%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +G+R+RT +T  Q + LEK F   +YL+   RI++A +L LS+ Q+K W+QNRRMKWKK
Sbjct: 112  KGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 170



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 27/57 (47%), Positives = 39/57 (68%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           +R R  +T  Q + LEK F   +YL+   RI++A +L L++ Q+K W+QNRRMKWKK
Sbjct: 114 RRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 170



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 38/96 (39%), Positives = 50/96 (52%), Gaps = 21/96 (21%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK----ENKLINSTQPSG- 713
           LEK F   +YL+   RI++A +L L++ Q+K W+QNRRMKWKK       L + T+P G 
Sbjct: 128 LEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGR 187

Query: 714 -------------EDSEAKAGEEPGPTRWVQGEPSD 736
                        E   AK  E+P     V GEPSD
Sbjct: 188 PKKNSIPTSEQLTEQERAKDAEKPAE---VPGEPSD 220



>gi|12644227|sp|P35452|HXD12_HUMAN   Homeobox protein Hox-D12 (Hox-4H)
          Length = 275

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 32/63 (50%), Positives = 46/63 (73%), Gaps = 1/63 (1%)

Query: 1044 GGP-EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 1102
            GGP E ++ R  YT+ Q  ELE EF  N ++ R++R E+++ L LS++Q+KIWFQNRRMK
Sbjct: 202  GGPGEARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMK 261

Query: 1103 WKK 1105
             K+
Sbjct: 262  KKR 264



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/62 (46%), Positives = 46/62 (74%), Gaps = 1/62 (1%)

Query: 293 GP-DRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           GP + ++ R+ YT+ Q  ELE EF  N ++ R++R E+++ L L+++Q+KIWFQNRRMK 
Sbjct: 203 GPGEARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKK 262

Query: 352 KK 353
           K+
Sbjct: 263 KR 264



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 24/44 (54%), Positives = 35/44 (79%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELE EF  N ++ R++R E++N L L+++Q+KIWFQNRRMK K+
Sbjct: 221 ELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 264



>gi|12231013|sp|Q03828|EVX2_HUMAN   Homeobox even-skipped homolog protein 2 (EVX-2)
          Length = 476

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 34/62 (54%), Positives = 43/62 (69%)

Query: 1044 GGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            G  + +R RTA+TR Q   LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK 
Sbjct: 184  GADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKD 243

Query: 1104 KK 1105
            K+
Sbjct: 244  KR 245



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 34/64 (53%), Positives = 44/64 (68%), Gaps = 1/64 (1%)

Query: 292 SGPDR-KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           SG D+ +R R  +TR Q   LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK
Sbjct: 183 SGADQVRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMK 242

Query: 351 WKKE 354
            K++
Sbjct: 243 DKRQ 246



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 27/54 (50%), Positives = 37/54 (68%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPS 712
           LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK K++   ++   P+
Sbjct: 203 LEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPA 256



>gi|14917010|sp|Q05925|HME1_HUMAN   Homeobox protein engrailed-1 (Hu-En-1)
          Length = 392

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 34/65 (52%), Positives = 43/65 (66%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            E KR RTA+T  Q   L+ EF  NRY+T +RR  +A  L L+E QIKIWFQN+R K KK 
Sbjct: 302  EDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKA 361

Query: 1107 NKLKS 1111
              +K+
Sbjct: 362  TGIKN 366



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 30/57 (52%), Positives = 36/57 (63%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           KR R  +T  Q   L+ EF  NRY+T +RR  +A  L L E QIKIWFQN+R K KK
Sbjct: 304 KRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK 360



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 26/49 (53%), Positives = 32/49 (65%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLIN 707
           L+ EF  NRY+T +RR  +A  L L E QIKIWFQN+R K KK   + N
Sbjct: 318 LKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKN 366



>gi|21903415|sp|P19622|HME2_HUMAN   Homeobox protein engrailed-2 (Hu-En-2)
          Length = 333

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 34/59 (57%), Positives = 40/59 (67%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            E KR RTA+T  Q   L+ EF  NRYLT +RR  +A  L L+E QIKIWFQN+R K KK
Sbjct: 243  EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 32/67 (47%), Positives = 40/67 (59%)

Query: 287 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN 346
           P  ++   + KR R  +T  Q   L+ EF  NRYLT +RR  +A  L L E QIKIWFQN
Sbjct: 235 PKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQN 294

Query: 347 RRMKWKK 353
           +R K KK
Sbjct: 295 KRAKIKK 301



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 26/43 (60%), Positives = 30/43 (69%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           L+ EF  NRYLT +RR  +A  L L E QIKIWFQN+R K KK
Sbjct: 259 LKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301



>gi|547658|sp|Q03014|HHEX_HUMAN   Homeobox protein PRH (Hematopoietically expressed homeobox)
           (Homeobox protein HEX)
          Length = 270

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 32/82 (39%), Positives = 52/82 (63%)

Query: 287 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN 346
           P+++     RK G+  ++  QT+ELEK+F   +YL+   R  +A  L L+ERQ+K WFQN
Sbjct: 128 PFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQN 187

Query: 347 RRMKWKKEHKDEAQAHQPPLLE 368
           RR KW++  ++  Q+++   LE
Sbjct: 188 RRAKWRRLKQENPQSNKKEELE 209



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 18/95 (18%)

Query: 1029 IYPWMRKLH------ISHDNIGGP------------EGKRARTAYTRYQTLELEKEFHFN 1070
            +YP+ R ++      + HD +G P            + K  +  ++  QT+ELEK+F   
Sbjct: 100  LYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQ 159

Query: 1071 RYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +YL+   R  +A  L LSERQ+K WFQNRR KW++
Sbjct: 160  KYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRR 194



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 3/57 (5%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKW---KKENKLINSTQ 710
           +ELEK+F   +YL+   R  +A  L L+ERQ+K WFQNRR KW   K+EN   N  +
Sbjct: 150 IELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKE 206



>gi|1352398|sp|P49640|EVX1_HUMAN   Homeobox even-skipped homolog protein 1 (EVX-1)
          Length = 407

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 33/57 (57%), Positives = 41/57 (71%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +R RTA+TR Q   LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK K+
Sbjct: 184  RRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKR 240



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 32/64 (50%), Positives = 42/64 (65%)

Query: 291 SSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           S+    +R R  +TR Q   LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK
Sbjct: 178 SASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMK 237

Query: 351 WKKE 354
            K++
Sbjct: 238 DKRQ 241



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 27/54 (50%), Positives = 36/54 (66%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPS 712
           LEKEF+   Y++R RR E+A AL L E  IK+WFQNRRMK K++   +    P+
Sbjct: 198 LEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPA 251



>gi|27923733|sp|Q96QS3|ARX_HUMAN   Homeobox protein ARX (Aristaless-related homeobox)
          Length = 562

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 33/71 (46%), Positives = 43/71 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+T YQ  ELE+ F    Y     R E+A  L LTE ++++WFQNRR KW+K  
Sbjct: 328 QRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKRE 387

Query: 356 KDEAQAHQPPL 366
           K  AQ H P L
Sbjct: 388 KAGAQTHPPGL 398



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 27/60 (45%), Positives = 37/60 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T YQ  ELE+ F    Y     R E+A  L L+E ++++WFQNRR KW+K  K
Sbjct: 329  RRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK 388



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/56 (44%), Positives = 32/56 (57%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG 713
           ELE+ F    Y     R E+A  L LTE ++++WFQNRR KW+K  K    T P G
Sbjct: 342 ELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPG 397



>gi|20141538|sp|P31275|HXC12_HUMAN   Homeobox protein Hox-C12 (Hox-3F)
          Length = 282

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 32/67 (47%), Positives = 47/67 (70%), Gaps = 1/67 (1%)

Query: 287 PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN 346
           PW   +   RK+ R+ Y++ Q  ELE EF  N ++TR+RR E++  L L+++Q+KIWFQN
Sbjct: 206 PWYPINSRSRKK-RKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQN 264

Query: 347 RRMKWKK 353
           RRMK K+
Sbjct: 265 RRMKKKR 271



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/57 (50%), Positives = 42/57 (73%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ R  Y++ Q  ELE EF  N ++TR+RR E++  L LS++Q+KIWFQNRRMK K+
Sbjct: 215  RKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 25/44 (56%), Positives = 36/44 (81%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELE EF  N ++TR+RR E+++ L L+++Q+KIWFQNRRMK K+
Sbjct: 228 ELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271



>gi|20532295|sp|Q9UIW0|VAX2_HUMAN   Ventral anterior homeobox 2
          Length = 290

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 35/75 (46%), Positives = 46/75 (61%), Gaps = 2/75 (2%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            KR RT++T  Q   LE EF   +Y+  R R E+A  L LSE Q+K+WFQNRR K KKD  
Sbjct: 103  KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQS 162

Query: 1109 --LKSMSMAAAGGAF 1121
              L+  + ++A  AF
Sbjct: 163  RDLEKRASSSASEAF 177



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 28/64 (43%), Positives = 39/64 (60%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R ++T  Q   LE EF   +Y+  R R E+A  L L+E Q+K+WFQNRR K KK+  
Sbjct: 103 KRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQS 162

Query: 357 DEAQ 360
            + +
Sbjct: 163 RDLE 166



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 28/62 (45%), Positives = 36/62 (58%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LE EF   +Y+  R R E+A  L L+E Q+K+WFQNRR K KK+       + S   SEA
Sbjct: 117 LEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEA 176

Query: 719 KA 720
            A
Sbjct: 177 FA 178



>gi|29336920|sp|Q9BZE3|BARH1_HUMAN   BarH-like 1 homeobox protein (FKSG31 protein)
          Length = 327

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 29/70 (41%), Positives = 48/70 (68%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ARTA+T +Q  +LE+ F   +YL+ + R+E+A +L L++ Q+K W+QNRR KWK+   
Sbjct: 179  RKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTA 238

Query: 1109 LKSMSMAAAG 1118
            +    +A AG
Sbjct: 239  VGLELLAEAG 248



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 19/134 (14%)

Query: 240 ADAYGNLPCASYDQN------IPG--LCSDLAKGACDKTDEGALHGAAEANFRI------ 285
           AD      CA Y  +       PG  L +  A+   DK D+   + ++++ +++      
Sbjct: 103 ADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFRDKLDKSGSNASSDSEYKVKEEGDR 162

Query: 286 -YPWMRSSGPDR----KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQI 340
                R S P R    ++ R  +T +Q  +LE+ F   +YL+ + R+E+A +L LT+ Q+
Sbjct: 163 EISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYLSVQDRMELAASLNLTDTQV 222

Query: 341 KIWFQNRRMKWKKE 354
           K W+QNRR KWK++
Sbjct: 223 KTWYQNRRTKWKRQ 236



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 29/83 (34%), Positives = 46/83 (55%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           +LE+ F   +YL+ + R+E+A +L LT+ Q+K W+QNRR KWK++  +         +  
Sbjct: 192 QLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYS 251

Query: 718 AKAGEEPGPTRWVQGEPSDLGPG 740
           A     P P  + Q   S+L PG
Sbjct: 252 ALQRMFPSPYFYPQSLVSNLDPG 274



>gi|6016211|sp|P78426|NK61_HUMAN   Homeobox protein Nkx-6.1
          Length = 367

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 29/63 (46%), Positives = 40/63 (63%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           RK  R T++  Q   LEK F   +YL    R  +A++L +TE Q+K+WFQNRR KW+K+H
Sbjct: 236 RKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 295

Query: 356 KDE 358
             E
Sbjct: 296 AAE 298



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 25/112 (22%)

Query: 608 QGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNR 667
           QG  L D+   RK+T P +   Q                            LEK F   +
Sbjct: 225 QGSILLDKDGKRKHTRPTFSGQQ-------------------------IFALEKTFEQTK 259

Query: 668 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAK 719
           YL    R  +A +L +TE Q+K+WFQNRR KW+K++    +T    +DSE +
Sbjct: 260 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETE 311



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 24/57 (42%), Positives = 35/57 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            K  R  ++  Q   LEK F   +YL    R  +A++L ++E Q+K+WFQNRR KW+K
Sbjct: 237  KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 293



>gi|2828197|sp|P31271|HXA13_HUMAN   Homeobox protein Hox-A13 (Hox-1J)
          Length = 388

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 33/67 (49%), Positives = 47/67 (70%), Gaps = 1/67 (1%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK-D 1106
            G++ R  YT+ Q  ELE+E+  N+++T+ +R  I+    LSERQ+ IWFQNRR+K KK  
Sbjct: 322  GRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVI 381

Query: 1107 NKLKSMS 1113
            NKLK+ S
Sbjct: 382  NKLKTTS 388



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 29/66 (43%), Positives = 43/66 (65%), Gaps = 3/66 (4%)

Query: 291 SSGPDRKRGRQT---YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           S     +RGR+    YT+ Q  ELE+E+  N+++T+ +R  I+    L+ERQ+ IWFQNR
Sbjct: 314 SDASSYRRGRKKRVPYTKVQLKELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNR 373

Query: 348 RMKWKK 353
           R+K KK
Sbjct: 374 RVKEKK 379



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 25/49 (51%), Positives = 36/49 (73%), Gaps = 1/49 (2%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKL 705
           ELE+E+  N+++T+ +R  I+    L+ERQ+ IWFQNRR+K KK  NKL
Sbjct: 336 ELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKL 384



>gi|6016210|sp|P78367|NK32_HUMAN   Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1)
          Length = 333

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 37/96 (38%), Positives = 51/96 (53%), Gaps = 18/96 (18%)

Query: 294 PDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           P +KR R  ++  Q  ELE+ F+  RYL+   R ++A +L LTE Q+KIWFQNRR K K+
Sbjct: 204 PRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 263

Query: 354 EHKDEAQAHQPPLLEGNVPELAADLWRPREAQKEVA 389
                              ++AADL     A K+VA
Sbjct: 264 R------------------QMAADLLASAPAAKKVA 281



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 29/60 (48%), Positives = 41/60 (68%)

Query: 1046 PEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            P  KR+R A++  Q  ELE+ F+  RYL+   R ++A +L L+E Q+KIWFQNRR K K+
Sbjct: 204  PRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 263



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 24/44 (54%), Positives = 32/44 (72%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELE+ F+  RYL+   R ++A +L LTE Q+KIWFQNRR K K+
Sbjct: 220 ELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 263



>gi|13431329|sp|Q9UMQ3|BARX2_HUMAN   Homeobox protein BarH-like 2
          Length = 254

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 27/57 (47%), Positives = 42/57 (73%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +R+RT +T  Q + LEK+F   +YL+   R+++A +L L++ Q+K W+QNRRMKWKK
Sbjct: 109  RRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 165



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 27/57 (47%), Positives = 40/57 (70%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           +R R  +T  Q + LEK+F   +YL+   R+++A +L LT+ Q+K W+QNRRMKWKK
Sbjct: 109 RRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 165



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 23/43 (53%), Positives = 33/43 (76%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           LEK+F   +YL+   R+++A +L LT+ Q+K W+QNRRMKWKK
Sbjct: 123 LEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 165



>gi|19862512|sp|Q04743|EMX2_HUMAN   Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty
            spiracles-like protein 2)
          Length = 252

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 36/92 (39%), Positives = 50/92 (54%), Gaps = 16/92 (17%)

Query: 1030 YPWM--RKLHISH---DNIGGPEG-----------KRARTAYTRYQTLELEKEFHFNRYL 1073
            YPW+  R  ++ H    N   PE            KR RTA++  Q L LE  F  N Y+
Sbjct: 120  YPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYV 179

Query: 1074 TRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
                R ++AH+L L+E Q+K+WFQNRR K+K+
Sbjct: 180  VGAERKQLAHSLSLTETQVKVWFQNRRTKFKR 211



 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 28/62 (45%), Positives = 40/62 (64%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R  ++  Q L LE  F  N Y+    R ++AH+L LTE Q+K+WFQNRR K+K++  
Sbjct: 155 KRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKL 214

Query: 357 DE 358
           +E
Sbjct: 215 EE 216



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 28/73 (38%), Positives = 40/73 (54%), Gaps = 5/73 (6%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 716
           L LE  F  N Y+    R ++A++L LTE Q+K+WFQNRR K+K++       +  G DS
Sbjct: 167 LRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ-----KLEEEGSDS 221

Query: 717 EAKAGEEPGPTRW 729
           + K        RW
Sbjct: 222 QQKKKGTHHINRW 234



>gi|47117915|sp|Q9NY43|BARH2_HUMAN   BarH-like 2 homeobox protein
          Length = 387

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 28/70 (40%), Positives = 48/70 (68%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ARTA++ +Q  +LE+ F   +YL+ + R+++A AL L++ Q+K W+QNRR KWK+   
Sbjct: 233  RKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTA 292

Query: 1109 LKSMSMAAAG 1118
            +    +A AG
Sbjct: 293  VGLELLAEAG 302



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 36/107 (33%), Positives = 58/107 (54%), Gaps = 8/107 (7%)

Query: 256 PGLCSDLAKGACDKTDEGA----LHGAAEANFRIYPWMRSSGPDR----KRGRQTYTRYQ 307
           P L  + +K   DK ++       HG  E   R     R S P R    ++ R  ++ +Q
Sbjct: 184 PKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQ 243

Query: 308 TLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 354
             +LE+ F   +YL+ + R+++A AL LT+ Q+K W+QNRR KWK++
Sbjct: 244 LNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 21/45 (46%), Positives = 34/45 (75%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           +LE+ F   +YL+ + R+++A AL LT+ Q+K W+QNRR KWK++
Sbjct: 246 QLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290



>gi|27923815|sp|Q8TAU0|NKX23_HUMAN   Homeobox protein Nkx-2.3 (Homeobox protein NKX-2.3) (Homeobox
           protein NK-2 homolog C)
          Length = 364

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 32/73 (43%), Positives = 45/73 (61%), Gaps = 3/73 (4%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           R++ R  +++ Q  ELE+ F   RYL+   R  +A +L LT  Q+KIWFQNRR K K++ 
Sbjct: 148 RRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQR 207

Query: 356 KD---EAQAHQPP 365
           +D   E  AH PP
Sbjct: 208 QDKSLELGAHAPP 220



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 27/68 (39%), Positives = 42/68 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  +++ Q  ELE+ F   RYL+   R  +A +L L+  Q+KIWFQNRR K K+  +
Sbjct: 149  RKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQ 208

Query: 1109 LKSMSMAA 1116
             KS+ + A
Sbjct: 209  DKSLELGA 216



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/47 (48%), Positives = 32/47 (68%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE+ F   RYL+   R  +A++L LT  Q+KIWFQNRR K K++ +
Sbjct: 162 ELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQ 208



>gi|50403792|sp|Q92826|HXB13_HUMAN   Homeobox protein Hox-B13
          Length = 284

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 29/58 (50%), Positives = 43/58 (74%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            G++ R  Y++ Q  ELE+E+  N+++T+ +R +I+ A  LSERQI IWFQNRR+K KK
Sbjct: 216  GRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 29/60 (48%), Positives = 44/60 (73%), Gaps = 3/60 (5%)

Query: 297 KRGRQT---YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           +RGR+    Y++ Q  ELE+E+  N+++T+ +R +I+ A  L+ERQI IWFQNRR+K KK
Sbjct: 214 RRGRKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKK 273



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 28/55 (50%), Positives = 40/55 (72%), Gaps = 1/55 (1%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKLINSTQP 711
           ELE+E+  N+++T+ +R +I+ A  L+ERQI IWFQNRR+K KK   K+ NS  P
Sbjct: 230 ELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP 284



>gi|2833256|sp|Q14774|HLX1_HUMAN   Homeobox protein HLX1 (Homeobox protein HB24)
          Length = 488

 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 30/68 (44%), Positives = 42/68 (61%), Gaps = 2/68 (2%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           R   R  ++  Q   LEK F   +Y+T+  R ++A  L LT+ Q+K+WFQNRRMKW+  H
Sbjct: 276 RSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWR--H 333

Query: 356 KDEAQAHQ 363
             EAQA +
Sbjct: 334 SKEAQAQK 341



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 6/82 (7%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LEK F   +Y+T+  R ++A  L LT+ Q+K+WFQNRRMKW+   +       + +D + 
Sbjct: 291 LEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKE-----AQAQKDKDK 345

Query: 719 KAGEEP-GPTRWVQGEPSDLGP 739
           +AGE+P G      GE  +  P
Sbjct: 346 EAGEKPSGGAPAADGEQDERSP 367



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 23/61 (37%), Positives = 39/61 (63%)

Query: 1051 ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLK 1110
            +R  ++  Q   LEK F   +Y+T+  R ++A  L L++ Q+K+WFQNRRMKW+   + +
Sbjct: 279  SRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQ 338

Query: 1111 S 1111
            +
Sbjct: 339  A 339



>gi|20141539|sp|P31276|HXC13_HUMAN   Homeobox protein Hox-C13 (Hox-3G)
          Length = 330

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 28/58 (48%), Positives = 41/58 (70%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            G++ R  YT+ Q  ELEKE+  ++++T+ +R  I+    LSERQ+ IWFQNRR+K KK
Sbjct: 260  GRKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 26/57 (45%), Positives = 40/57 (70%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           ++ R  YT+ Q  ELEKE+  ++++T+ +R  I+    L+ERQ+ IWFQNRR+K KK
Sbjct: 261 RKKRVPYTKVQLKELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 22/44 (50%), Positives = 33/44 (75%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELEKE+  ++++T+ +R  I+    L+ERQ+ IWFQNRR+K KK
Sbjct: 274 ELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317



>gi|2851475|sp|P35453|HXD13_HUMAN   Homeobox protein Hox-D13 (Hox-4I)
          Length = 335

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 28/58 (48%), Positives = 40/58 (68%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            G++ R  YT+ Q  ELE E+  N+++ + +R  I+ A  LSERQ+ IWFQNRR+K KK
Sbjct: 268  GRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 26/57 (45%), Positives = 39/57 (68%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           ++ R  YT+ Q  ELE E+  N+++ + +R  I+ A  L+ERQ+ IWFQNRR+K KK
Sbjct: 269 RKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 22/44 (50%), Positives = 32/44 (72%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELE E+  N+++ + +R  I+ A  L+ERQ+ IWFQNRR+K KK
Sbjct: 282 ELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325



>gi|57015304|sp|Q04741|EMX1_HUMAN   Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty
            spiracles-like protein 1)
          Length = 257

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 28/57 (49%), Positives = 39/57 (68%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            KR RTA++  Q L LE+ F  N Y+    R ++A +L LSE Q+K+WFQNRR K+K+
Sbjct: 160  KRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKR 216



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 26/62 (41%), Positives = 40/62 (64%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R  ++  Q L LE+ F  N Y+    R ++A +L L+E Q+K+WFQNRR K+K++  
Sbjct: 160 KRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKL 219

Query: 357 DE 358
           +E
Sbjct: 220 EE 221



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 27/73 (36%), Positives = 40/73 (54%), Gaps = 5/73 (6%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 716
           L LE+ F  N Y+    R ++A +L L+E Q+K+WFQNRR K+K++       +  G +S
Sbjct: 172 LRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQ-----KLEEEGPES 226

Query: 717 EAKAGEEPGPTRW 729
           E K        RW
Sbjct: 227 EQKKKGSHHINRW 239



>gi|6016208|sp|O15522|NK28_HUMAN   Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H)
          Length = 239

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 44/124 (35%), Positives = 63/124 (50%), Gaps = 13/124 (10%)

Query: 247 PCASYDQNIPGLCSDLAKGACDKTDEGALHGAA-EANFRIYPWMRSSGPD---RKRGRQT 302
           PCA++         D  +G    +DE +L  +  +++ R      S G D   RK+ R  
Sbjct: 39  PCAAW--------LDSERGHYPSSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVL 90

Query: 303 YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAH 362
           +++ QTLELE+ F   RYL+   R ++A  L LT  Q+KIWFQN R K K+     A A 
Sbjct: 91  FSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRARAPGA-AE 149

Query: 363 QPPL 366
            P L
Sbjct: 150 SPDL 153



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 26/57 (45%), Positives = 37/57 (64%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            K+ R  +++ QTLELE+ F   RYL+   R ++A  L L+  Q+KIWFQN R K K+
Sbjct: 85   KKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 23/45 (51%), Positives = 30/45 (66%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           LELE+ F   RYL+   R ++A+ L LT  Q+KIWFQN R K K+
Sbjct: 97  LELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141



>gi|17377578|sp|Q99801|NKX31_HUMAN   Homeobox protein Nkx-3.1
          Length = 234

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 27/57 (47%), Positives = 39/57 (68%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            KR+R A++  Q +ELE++F   +YL+   R  +A  L L+E Q+KIWFQNRR K K+
Sbjct: 125  KRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 27/59 (45%), Positives = 39/59 (66%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 354
           +KR R  ++  Q +ELE++F   +YL+   R  +A  L LTE Q+KIWFQNRR K K++
Sbjct: 124 QKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 23/46 (50%), Positives = 32/46 (69%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           +ELE++F   +YL+   R  +A  L LTE Q+KIWFQNRR K K++
Sbjct: 137 IELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182



>gi|27923817|sp|Q9H2Z4|NK24_HUMAN   Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox
           protein NK-2 homolog D)
          Length = 353

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 11/87 (12%)

Query: 273 GALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 332
           G LH AA A          + P RKR R  +++ Q  ELE+ F   +YL+   R  +A  
Sbjct: 177 GPLHAAAAA----------AAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASM 225

Query: 333 LCLTERQIKIWFQNRRMKWKKEHKDEA 359
           + LT  Q+KIWFQN R K K++ KD+A
Sbjct: 226 IHLTPTQVKIWFQNHRYKMKRQAKDKA 252



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/75 (33%), Positives = 39/75 (52%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  +++ Q  ELE+ F   +YL+   R  +A  + L+  Q+KIWFQN R K K+  K
Sbjct: 190  RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAK 249

Query: 1109 LKSMSMAAAGGAFRP 1123
             K+       G   P
Sbjct: 250  DKAAQQLQQEGGLGP 264



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 21/47 (44%), Positives = 30/47 (63%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE+ F   +YL+   R  +A+ + LT  Q+KIWFQN R K K++ K
Sbjct: 203 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAK 249



>gi|23503066|sp|P28360|MSX1_HUMAN   Homeobox protein MSX-1 (Hox-7)
          Length = 297

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 30/70 (42%), Positives = 46/70 (65%), Gaps = 2/70 (2%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK--D 1106
            ++ RT +T  Q L LE++F   +YL+   R E + +L L+E Q+KIWFQNRR K K+  +
Sbjct: 167  RKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQE 226

Query: 1107 NKLKSMSMAA 1116
             +L+ + MAA
Sbjct: 227  AELEKLKMAA 236



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 27/64 (42%), Positives = 40/64 (62%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           ++ R  +T  Q L LE++F   +YL+   R E + +L LTE Q+KIWFQNRR K K+  +
Sbjct: 167 RKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQE 226

Query: 357 DEAQ 360
            E +
Sbjct: 227 AELE 230



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/45 (51%), Positives = 32/45 (71%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           L LE++F   +YL+   R E +++L LTE Q+KIWFQNRR K K+
Sbjct: 179 LALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 223



>gi|1708211|sp|P52952|NK25_HUMAN   Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E)
           (Cardiac-specific homeobox) (Homeobox protein CSX)
          Length = 324

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 27/63 (42%), Positives = 41/63 (65%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           R++ R  +++ Q  ELE+ F   RYL+   R ++A  L LT  Q+KIWFQNRR K K++ 
Sbjct: 138 RRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQR 197

Query: 356 KDE 358
           +D+
Sbjct: 198 QDQ 200



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 28/77 (36%), Positives = 44/77 (57%), Gaps = 3/77 (3%)

Query: 1041 DNIGGPEGKRAR---TAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQ 1097
            DN   P  +R R     +++ Q  ELE+ F   RYL+   R ++A  L L+  Q+KIWFQ
Sbjct: 128  DNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQ 187

Query: 1098 NRRMKWKKDNKLKSMSM 1114
            NRR K K+  + +++ +
Sbjct: 188  NRRYKCKRQRQDQTLEL 204



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 23/47 (48%), Positives = 32/47 (68%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE+ F   RYL+   R ++A+ L LT  Q+KIWFQNRR K K++ +
Sbjct: 152 ELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQ 198



>gi|1174819|sp|P43699|TITF1_HUMAN   Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1)
           (Homeobox protein Nkx-2.1) (Homeobox protein NK-2
           homolog A)
          Length = 371

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 31/72 (43%), Positives = 43/72 (59%), Gaps = 1/72 (1%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           S P RKR R  +++ Q  ELE+ F   +YL+   R  +A  + LT  Q+KIWFQN R K 
Sbjct: 158 SAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKM 216

Query: 352 KKEHKDEAQAHQ 363
           K++ KD+A   Q
Sbjct: 217 KRQAKDKAAQQQ 228



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 23/63 (36%), Positives = 37/63 (58%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            ++ R  +++ Q  ELE+ F   +YL+   R  +A  + L+  Q+KIWFQN R K K+  K
Sbjct: 162  RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAK 221

Query: 1109 LKS 1111
             K+
Sbjct: 222  DKA 224



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 25/64 (39%), Positives = 36/64 (56%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELE+ F   +YL+   R  +A+ + LT  Q+KIWFQN R K K++ K   + Q   +DS 
Sbjct: 175 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSG 234

Query: 718 AKAG 721
              G
Sbjct: 235 GGGG 238



>gi|3913487|sp|O60479|DLX3_HUMAN   Homeobox protein DLX-3
          Length = 287

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 40/117 (34%), Positives = 58/117 (49%), Gaps = 12/117 (10%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           ++ R  Y+ YQ   L++ F   +YL    R E+A  L LT+ Q+KIWFQNRR K+KK +K
Sbjct: 130 RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYK 189

Query: 357 D-----EAQAHQPPLLEGNVPELAADLW------RPREAQKEVARHTVFPASPLGLD 402
           +     E   +    +  N P   A LW       P  A+ ++     + ASP  LD
Sbjct: 190 NGEVPLEHSPNNSDSMACNSPPSPA-LWDTSSHSTPAPARSQLPPPLPYSASPSYLD 245



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 26/57 (45%), Positives = 37/57 (64%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ RT Y+ YQ   L++ F   +YL    R E+A  L L++ Q+KIWFQNRR K+KK
Sbjct: 130  RKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK 186



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 33/93 (35%), Positives = 45/93 (48%), Gaps = 4/93 (4%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWK---KENKLINSTQPSGED 715
           L++ F   +YL    R E+A  L LT+ Q+KIWFQNRR K+K   K  ++     P+  D
Sbjct: 144 LQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSD 203

Query: 716 SEAKAGEEPGPTRWVQGEPSDLGPGWLEEPDPV 748
           S A     P P  W     S   P   + P P+
Sbjct: 204 SMA-CNSPPSPALWDTSSHSTPAPARSQLPPPL 235



>gi|17380297|sp|Q9Y2V3|RX_HUMAN   Retinal homeobox protein Rx (Retina and anterior neural fold homeobox
            protein)
          Length = 346

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/66 (42%), Positives = 41/66 (62%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T YQ  ELE+ F  + Y     R E+A  + L E ++++WFQNRR KW++  K
Sbjct: 137  RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK 196

Query: 1109 LKSMSM 1114
            L+  SM
Sbjct: 197  LEVSSM 202



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 26/65 (40%), Positives = 40/65 (61%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +R R T+T YQ  ELE+ F  + Y     R E+A  + L E ++++WFQNRR KW+++ K
Sbjct: 137 RRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEK 196

Query: 357 DEAQA 361
            E  +
Sbjct: 197 LEVSS 201



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELE+ F  + Y     R E+A  + L E ++++WFQNRR KW+++ KL  S+    +DS 
Sbjct: 150 ELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKL-QDSP 208

Query: 718 AKAGEEPGPTRWVQGEPSDLGPG 740
             +     P+  +   P   GPG
Sbjct: 209 LLSFSRSPPSATL--SPLGAGPG 229



>gi|13959687|sp|P35548|MSX2_HUMAN   Homeobox protein MSX-2 (Hox-8)
          Length = 267

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 30/70 (42%), Positives = 46/70 (65%), Gaps = 2/70 (2%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK--D 1106
            ++ RT +T  Q L LE++F   +YL+   R E + +L L+E Q+KIWFQNRR K K+  +
Sbjct: 143  RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202

Query: 1107 NKLKSMSMAA 1116
             +L+ + MAA
Sbjct: 203  AELEKLKMAA 212



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 27/64 (42%), Positives = 40/64 (62%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           ++ R  +T  Q L LE++F   +YL+   R E + +L LTE Q+KIWFQNRR K K+  +
Sbjct: 143 RKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202

Query: 357 DEAQ 360
            E +
Sbjct: 203 AELE 206



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 23/45 (51%), Positives = 32/45 (71%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           L LE++F   +YL+   R E +++L LTE Q+KIWFQNRR K K+
Sbjct: 155 LALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199



>gi|1730095|sp|P52954|LBX1_HUMAN   Transcription factor LBX1
          Length = 280

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 31/79 (39%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 290 RSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRM 349
           R +   R++ R  +T +Q  ELEK F + +YL+   R +IA  L LT  Q+  WFQNRR 
Sbjct: 118 RQTPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRA 177

Query: 350 KWKKEHKD-EAQAHQPPLL 367
           K K+E ++ +A    P  L
Sbjct: 178 KLKRELEEMKADVESPKKL 196



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 26/58 (44%), Positives = 39/58 (67%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            +++RTA+T +Q  ELEK F + +YL+   R +IA  L L+  Q+  WFQNRR K K++
Sbjct: 125  RKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRE 182



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/45 (51%), Positives = 29/45 (64%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELEK F + +YL+   R +IA  L LT  Q+  WFQNRR K K+E
Sbjct: 138 ELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRE 182



>gi|12644329|sp|P56178|DLX5_HUMAN   Homeobox protein DLX-5
          Length = 289

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK--E 354
           ++ R  Y+ +Q   L++ F   +YL    R E+A +L LT+ Q+KIWFQN+R K KK  +
Sbjct: 138 RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK 197

Query: 355 HKDEAQAHQPPL---LEGNVPELAADLWRPREAQKEVARH 391
           + +    H P     +  N P+  A +W P+ + + ++ H
Sbjct: 198 NGEMPPEHSPSSSDPMACNSPQSPA-VWEPQGSSRSLSHH 236



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 24/57 (42%), Positives = 37/57 (64%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ RT Y+ +Q   L++ F   +YL    R E+A +L L++ Q+KIWFQN+R K KK
Sbjct: 138  RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK 194



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQP---SGED 715
           L++ F   +YL    R E+A +L LT+ Q+KIWFQN+R K KK  K  N   P   S   
Sbjct: 152 LQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKKIMK--NGEMPPEHSPSS 209

Query: 716 SEAKAGEEP-GPTRW 729
           S+  A   P  P  W
Sbjct: 210 SDPMACNSPQSPAVW 224



>gi|13626112|sp|Q9H161|ALX4_HUMAN   Homeobox protein aristaless-like 4
          Length = 411

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 26/61 (42%), Positives = 37/61 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+T YQ  ELEK F    Y     R ++A    LTE ++++WFQNRR KW+K  
Sbjct: 214 KRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRE 273

Query: 356 K 356
           +
Sbjct: 274 R 274



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 26/64 (40%), Positives = 37/64 (57%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T YQ  ELEK F    Y     R ++A    L+E ++++WFQNRR KW+K  +
Sbjct: 215  RRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 274

Query: 1109 LKSM 1112
               M
Sbjct: 275  FGQM 278



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 20/47 (42%), Positives = 28/47 (59%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEK F    Y     R ++A    LTE ++++WFQNRR KW+K  +
Sbjct: 228 ELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 274



>gi|2506529|sp|Q07687|DLX2_HUMAN   Homeobox protein DLX-2
          Length = 328

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 30/77 (38%), Positives = 44/77 (57%), Gaps = 1/77 (1%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           ++ R  Y+ +Q   L++ F   +YL    R E+A +L LT+ Q+KIWFQNRR K+KK  K
Sbjct: 153 RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWK 212

Query: 357 D-EAQAHQPPLLEGNVP 372
             E  + Q P    + P
Sbjct: 213 SGEIPSEQHPGASASPP 229



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 25/57 (43%), Positives = 38/57 (66%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ RT Y+ +Q   L++ F   +YL    R E+A +L L++ Q+KIWFQNRR K+KK
Sbjct: 153  RKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKK 209



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 32/86 (37%), Positives = 44/86 (51%), Gaps = 4/86 (4%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK--ENKLINSTQPSGEDS 716
           L++ F   +YL    R E+A +L LT+ Q+KIWFQNRR K+KK  ++  I S Q  G  +
Sbjct: 167 LQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKKMWKSGEIPSEQHPGASA 226

Query: 717 EAKAGEEP--GPTRWVQGEPSDLGPG 740
                  P   P  W  G P  +  G
Sbjct: 227 SPPCASPPVSAPASWDFGVPQRMAGG 252



>gi|48428084|sp|Q8N693|ESX1L_HUMAN   Extraembryonic, spermatogenesis, homeobox 1-like protein
          Length = 406

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 30/79 (37%), Positives = 46/79 (58%), Gaps = 1/79 (1%)

Query: 1046 PEGKRAR-TAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            PE KR R TA+T++Q  ELE  F  ++Y     R  +A  L L+E ++++WFQNRR KWK
Sbjct: 136  PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195

Query: 1105 KDNKLKSMSMAAAGGAFRP 1123
            ++ ++  +   A      P
Sbjct: 196  RNQRVLMLRNTATADLAHP 214



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 28/64 (43%), Positives = 42/64 (65%), Gaps = 1/64 (1%)

Query: 294 PDRKRGRQT-YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 352
           P+RKR R+T +T++Q  ELE  F  ++Y     R  +A  L LTE ++++WFQNRR KWK
Sbjct: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195

Query: 353 KEHK 356
           +  +
Sbjct: 196 RNQR 199



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 20/49 (40%), Positives = 31/49 (63%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLI 706
           ELE  F  ++Y     R  +A  L LTE ++++WFQNRR KWK+  +++
Sbjct: 153 ELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVL 201



>gi|12644330|sp|P56179|DLX6_HUMAN   Homeobox protein DLX-6
          Length = 175

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 29/78 (37%), Positives = 43/78 (55%)

Query: 293 GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 352
           G   ++ R  Y+  Q   L   F   +YL    R E+A +L LT+ Q+KIWFQN+R K+K
Sbjct: 46  GKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFK 105

Query: 353 KEHKDEAQAHQPPLLEGN 370
           K  K  +  H+   L+G+
Sbjct: 106 KLLKQGSNPHESDPLQGS 123



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 25/61 (40%), Positives = 37/61 (60%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G + ++ RT Y+  Q   L   F   +YL    R E+A +L L++ Q+KIWFQN+R K+K
Sbjct: 46   GKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFK 105

Query: 1105 K 1105
            K
Sbjct: 106  K 106



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 21/43 (48%), Positives = 28/43 (65%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           L   F   +YL    R E+A +L LT+ Q+KIWFQN+R K+KK
Sbjct: 64  LNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 106



>gi|3024482|sp|P78337|PITX1_HUMAN   Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot)
          Length = 314

 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T  Q  ELE  F  NRY     R EIA    L+E ++++WF+NRR KW+K  +
Sbjct: 90   RRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149

Query: 1109 LKSMSMAAAG 1118
             + + +   G
Sbjct: 150  NQQLDLCKGG 159



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 26/63 (41%), Positives = 38/63 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q  ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  
Sbjct: 89  QRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRE 148

Query: 356 KDE 358
           +++
Sbjct: 149 RNQ 151



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 22/47 (46%), Positives = 29/47 (61%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  +
Sbjct: 103 ELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149



>gi|6016205|sp|O95096|NKX22_HUMAN   Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B)
          Length = 273

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 2/73 (2%)

Query: 1044 GGPEGKRA--RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRM 1101
            GG  GK+   R  +++ QT ELE+ F   RYL+   R  +A  + L+  Q+KIWFQN R 
Sbjct: 122  GGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRY 181

Query: 1102 KWKKDNKLKSMSM 1114
            K K+    K M +
Sbjct: 182  KMKRARAEKGMEV 194



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 29/73 (39%), Positives = 41/73 (56%), Gaps = 1/73 (1%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           +G  RKR R  +++ QT ELE+ F   RYL+   R  +A  + LT  Q+KIWFQN R K 
Sbjct: 125 AGKKRKR-RVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKM 183

Query: 352 KKEHKDEAQAHQP 364
           K+   ++     P
Sbjct: 184 KRARAEKGMEVTP 196



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 21/44 (47%), Positives = 28/44 (63%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           ELE+ F   RYL+   R  +A+ + LT  Q+KIWFQN R K K+
Sbjct: 142 ELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185



>gi|8247951|sp|P23759|PAX7_HUMAN   Paired box protein Pax-7 (HUP1)
          Length = 520

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 5/115 (4%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+T  Q  ELEK F    Y     R E+A    LTE ++++WF NRR +W+K+ 
Sbjct: 217 QRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQA 276

Query: 356 KDEAQAHQPPLLEGNVPELAADLWRPREAQKEVARHTVFPASPLGLDFCVFIHGP 410
                A    LL G  P        P +        + +P + +  D    +H P
Sbjct: 277 GANQLAAFNHLLPGGFPPTGMPTLPPYQLP-----DSTYPTTTISQDGGSTVHRP 326



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD-- 1106
            +R+RT +T  Q  ELEK F    Y     R E+A    L+E ++++WF NRR +W+K   
Sbjct: 218  RRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAG 277

Query: 1107 -NKLKSMSMAAAGG 1119
             N+L + +    GG
Sbjct: 278  ANQLAAFNHLLPGG 291



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 19/45 (42%), Positives = 27/45 (60%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELEK F    Y     R E+A    LTE ++++WF NRR +W+K+
Sbjct: 231 ELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275



>gi|38605720|sp|P56177|DLX1_HUMAN   Homeobox protein DLX-1
          Length = 255

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 47/153 (30%), Positives = 62/153 (40%), Gaps = 13/153 (8%)

Query: 593 HFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXX 652
           + S  Q Y   +S  Q + L D GAD + ++ V     R N       G           
Sbjct: 83  YISSVQSYPGSASLAQSR-LEDPGADSEKSTVVEGGEVRFNG-----KGKKIRKPRTIYC 136

Query: 653 XXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK-----LIN 707
                 L + F   +YL    R E+A +L LT+ Q+KIWFQN+R K+KK  K     L  
Sbjct: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEG 196

Query: 708 STQPSGEDSEAKAGEEPGPTRWVQGEPSDLGPG 740
           S   +G      AG  P P  W     S  G G
Sbjct: 197 SALANGR--ALSAGSPPVPPGWNPNSSSGKGSG 227



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 11/138 (7%)

Query: 228 YQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDK----TDEGALHGAAEANF 283
           +  P    Y     ++ + P  S  Q+ PG  S LA+   +     +++  +    E  F
Sbjct: 63  FSRPLGYPYVNSVSSHASSPYISSVQSYPGSAS-LAQSRLEDPGADSEKSTVVEGGEVRF 121

Query: 284 RIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIW 343
                    G   ++ R  Y   Q   L + F   +YL    R E+A +L LT+ Q+KIW
Sbjct: 122 N------GKGKKIRKPRTIYCSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIW 175

Query: 344 FQNRRMKWKKEHKDEAQA 361
           FQN+R K+KK  K    A
Sbjct: 176 FQNKRSKFKKLMKQGGAA 193



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 25/61 (40%), Positives = 37/61 (60%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G + ++ RT Y   Q   L + F   +YL    R E+A +L L++ Q+KIWFQN+R K+K
Sbjct: 125  GKKIRKPRTIYCSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFK 184

Query: 1105 K 1105
            K
Sbjct: 185  K 185



>gi|6174907|sp|Q99697|PITX2_HUMAN   Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription
           factor) (Solurshin) (ALL1 responsive protein ARP1)
          Length = 317

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 26/63 (41%), Positives = 38/63 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q  ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  
Sbjct: 85  QRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRE 144

Query: 356 KDE 358
           +++
Sbjct: 145 RNQ 147



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 27/70 (38%), Positives = 39/70 (55%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T  Q  ELE  F  NRY     R EIA    L+E ++++WF+NRR KW+K  +
Sbjct: 86   RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145

Query: 1109 LKSMSMAAAG 1118
             +   +   G
Sbjct: 146  NQQAELCKNG 155



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 22/47 (46%), Positives = 29/47 (61%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  +
Sbjct: 99  ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145



>gi|6093723|sp|O75364|PITX3_HUMAN   Pituitary homeobox 3 (Homeobox protein PITX3)
          Length = 302

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 26/63 (41%), Positives = 37/63 (58%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q  ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  
Sbjct: 62  QRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRE 121

Query: 356 KDE 358
           + +
Sbjct: 122 RSQ 124



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 26/57 (45%), Positives = 35/57 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +R RT +T  Q  ELE  F  NRY     R EIA    L+E ++++WF+NRR KW+K
Sbjct: 63   RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK 119



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 22/47 (46%), Positives = 29/47 (61%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE  F  NRY     R EIA    LTE ++++WF+NRR KW+K  +
Sbjct: 76  ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 122



>gi|3023579|sp|Q15699|CRT1_HUMAN   Cartilage homeoprotein 1 (CART-1)
          Length = 326

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 11/115 (9%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           S   ++R R T+T  Q  ELEK F    Y     R ++A    LTE ++++WFQNRR KW
Sbjct: 128 SSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKW 187

Query: 352 KKEHK----DEAQAHQPPLLEGNV-------PELAADLWRPREAQKEVARHTVFP 395
           +K  +     +A++H     + +V       P++  +LW    +   V    + P
Sbjct: 188 RKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWAGNASGGSVVTSCMLP 242



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 26/74 (35%), Positives = 40/74 (54%)

Query: 1042 NIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRM 1101
            N+   + +R RT +T  Q  ELEK F    Y     R ++A    L+E ++++WFQNRR 
Sbjct: 126  NVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRA 185

Query: 1102 KWKKDNKLKSMSMA 1115
            KW+K  +   +  A
Sbjct: 186  KWRKRERYGQIQQA 199



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 20/47 (42%), Positives = 28/47 (59%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEK F    Y     R ++A    LTE ++++WFQNRR KW+K  +
Sbjct: 146 ELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRER 192



>gi|51702790|sp|P63015|PAX6_MOUSE   Paired box protein Pax-6 (Oculorhombin)
 gi|6174889|sp|P26367|PAX6_HUMAN   Paired box protein Pax-6 (Oculorhombin) (Aniridia, type II protein)
          Length = 422

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 26/69 (37%), Positives = 41/69 (59%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT++T+ Q   LEKEF    Y     R  +A  + L E +I++WF NRR KW+++ K
Sbjct: 211  QRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK 270

Query: 1109 LKSMSMAAA 1117
            L++    A+
Sbjct: 271  LRNQRRQAS 279



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 27/76 (35%), Positives = 40/76 (52%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +R R ++T+ Q   LEKEF    Y     R  +A  + L E +I++WF NRR KW++E K
Sbjct: 211 QRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEK 270

Query: 357 DEAQAHQPPLLEGNVP 372
              Q  Q      ++P
Sbjct: 271 LRNQRRQASNTPSHIP 286



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 22/49 (44%), Positives = 29/49 (59%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLIN 707
           LEKEF    Y     R  +A  + L E +I++WF NRR KW++E KL N
Sbjct: 225 LEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRN 273



>gi|13626107|sp|O95076|ALX3_HUMAN   Homeobox protein aristaless-like 3 (Proline-rich transcription
           factor ALX3)
          Length = 343

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 24/61 (39%), Positives = 37/61 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T++ +Q  ELEK F    Y     R ++A    LTE ++++WFQNRR KW+K  
Sbjct: 153 KRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRE 212

Query: 356 K 356
           +
Sbjct: 213 R 213



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 23/57 (40%), Positives = 35/57 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +R RT ++ +Q  ELEK F    Y     R ++A    L+E ++++WFQNRR KW+K
Sbjct: 154  RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRK 210



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 20/47 (42%), Positives = 28/47 (59%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEK F    Y     R ++A    LTE ++++WFQNRR KW+K  +
Sbjct: 167 ELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRER 213



>gi|3287764|sp|O43186|CRX_HUMAN   Cone-rod homeobox protein
          Length = 299

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 26/70 (37%), Positives = 42/70 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+TR Q  ELE  F   +Y     R E+A  + L E ++++WF+NRR K +++ 
Sbjct: 39  QRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQR 98

Query: 356 KDEAQAHQPP 365
           + + Q  QPP
Sbjct: 99  QQQKQQQQPP 108



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 24/71 (33%), Positives = 38/71 (53%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +TR Q  ELE  F   +Y     R E+A  + L E ++++WF+NRR K ++  +
Sbjct: 40   RRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQ 99

Query: 1109 LKSMSMAAAGG 1119
             +       GG
Sbjct: 100  QQKQQQQPPGG 110



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 6/83 (7%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKLINSTQPSGEDS 716
           ELE  F   +Y     R E+A  + L E ++++WF+NRR K +++  +     QP G  +
Sbjct: 53  ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA 112

Query: 717 EA-----KAGEEPGPTRWVQGEP 734
           +A     KAG  P P+  V  +P
Sbjct: 113 KARPAKRKAGTSPRPSTDVCPDP 135



>gi|3914276|sp|O43316|PAX4_HUMAN   Paired box protein Pax-4
          Length = 350

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 8/129 (6%)

Query: 298 RGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKD 357
           R R  ++  Q   LEKEF   +Y     R ++A A  L E  +++WF NRR KW+++ K 
Sbjct: 172 RNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKL 231

Query: 358 EAQAHQPPLLEG-NVPELAADLWRPREAQKEVARHTVFPASPLGLDFCVFIHGPIWFCWI 416
           + +   P   +G  VP +A  +   +++   V    +    PLG   C  +      CW 
Sbjct: 232 KWEMQLPGASQGLTVPRVAPGIISAQQSPGSVPTAALPALEPLG-PSCYQL------CWA 284

Query: 417 PQQEETILD 425
              E  + D
Sbjct: 285 TAPERCLSD 293



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 26/63 (41%), Positives = 36/63 (57%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN 1107
            G R RT ++  Q   LEKEF   +Y     R ++A A  L E  +++WF NRR KW++  
Sbjct: 170  GHRNRTIFSPSQAEALEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQE 229

Query: 1108 KLK 1110
            KLK
Sbjct: 230  KLK 232



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 20/47 (42%), Positives = 29/47 (61%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 705
           LEKEF   +Y     R ++A A  L E  +++WF NRR KW+++ KL
Sbjct: 185 LEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKL 231



>gi|17374365|sp|P58304|CHX10_HUMAN   Homeobox protein CHX10 (Ceh-10 homeodomain containing homolog)
          Length = 361

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 29/69 (42%), Positives = 37/69 (53%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T YQ  ELEK F+   Y     R  +A    L E +I++WFQNRR KW+K  K
Sbjct: 149  RRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208

Query: 1109 LKSMSMAAA 1117
                S   A
Sbjct: 209  CWGRSSVMA 217



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/61 (42%), Positives = 35/61 (57%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T YQ  ELEK F+   Y     R  +A    L E +I++WFQNRR KW+K  
Sbjct: 148 KRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKRE 207

Query: 356 K 356
           K
Sbjct: 208 K 208



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/47 (44%), Positives = 27/47 (57%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEK F+   Y     R  +A    L E +I++WFQNRR KW+K  K
Sbjct: 162 ELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208



>gi|12230168|sp|Q9UBX0|HESX1_HUMAN   Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf)
          Length = 185

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 29/68 (42%), Positives = 39/68 (57%)

Query: 1048 GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN 1107
            G+R RTA+T+ Q   LE  F  N Y     R ++A  L L E +I+IWFQNRR K K+ +
Sbjct: 108  GRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSH 167

Query: 1108 KLKSMSMA 1115
            +     MA
Sbjct: 168  RESQFLMA 175



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 25/61 (40%), Positives = 35/61 (57%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +R R  +T+ Q   LE  F  N Y     R ++A  L L E +I+IWFQNRR K K+ H+
Sbjct: 109 RRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHR 168

Query: 357 D 357
           +
Sbjct: 169 E 169



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 20/46 (43%), Positives = 27/46 (58%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LE  F  N Y     R ++A  L L E +I+IWFQNRR K K+ ++
Sbjct: 123 LENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHR 168



>gi|8134644|sp|Q99453|PHX2B_HUMAN   Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B
            homeodomain protein) (Neuroblastoma Phox) (NBPhox)
          Length = 314

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 26/69 (37%), Positives = 41/69 (59%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T  Q  ELE+ F    Y     R E+A  + L+E ++++WFQNRR K++K  +
Sbjct: 99   RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQER 158

Query: 1109 LKSMSMAAA 1117
              + + AAA
Sbjct: 159  AAAAAAAAA 167



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 26/66 (39%), Positives = 40/66 (60%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+T  Q  ELE+ F    Y     R E+A  + LTE ++++WFQNRR K++K+ 
Sbjct: 98  QRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQE 157

Query: 356 KDEAQA 361
           +  A A
Sbjct: 158 RAAAAA 163



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 7/96 (7%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ------P 711
           ELE+ F    Y     R E+A  + LTE ++++WFQNRR K++K+ +   +         
Sbjct: 112 ELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNGS 171

Query: 712 SGEDSEAKAGEEPGPTRWVQGEPSDLGPGWLEEPDP 747
           SG+ S++   +E    +    + S  GPG    P P
Sbjct: 172 SGKKSDSSRDDESKEAKSTDPD-STGGPGPNPNPTP 206



>gi|3915680|sp|Q92988|DLX4_HUMAN   Homeobox protein DLX-4 (DLX-7) (DLX-8)
          Length = 347

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 23/57 (40%), Positives = 35/57 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            ++ RT Y+  Q   L + F   +YL    R ++A  L L++ Q+KIWFQN+R K+KK
Sbjct: 226  RKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKK 282



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 26/66 (39%), Positives = 37/66 (56%), Gaps = 2/66 (3%)

Query: 290 RSSGPDRK--RGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNR 347
           R   P +K  + R  Y+  Q   L + F   +YL    R ++A  L LT+ Q+KIWFQN+
Sbjct: 217 RPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNK 276

Query: 348 RMKWKK 353
           R K+KK
Sbjct: 277 RSKYKK 282



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 26/69 (37%), Positives = 38/69 (55%), Gaps = 9/69 (13%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           L + F   +YL    R ++A  L LT+ Q+KIWFQN+R K+KK  K         ++S  
Sbjct: 240 LNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK---------QNSGG 290

Query: 719 KAGEEPGPT 727
           + G+ PG T
Sbjct: 291 QEGDFPGRT 299



>gi|1172022|sp|P23760|PAX3_HUMAN   Paired box protein Pax-3 (HUP2)
          Length = 479

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 26/74 (35%), Positives = 41/74 (55%), Gaps = 3/74 (4%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD-- 1106
            +R+RT +T  Q  ELE+ F    Y     R E+A    L+E ++++WF NRR +W+K   
Sbjct: 220  RRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 279

Query: 1107 -NKLKSMSMAAAGG 1119
             N+L + +    GG
Sbjct: 280  ANQLMAFNHLIPGG 293



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 23/59 (38%), Positives = 35/59 (59%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 354
           ++R R T+T  Q  ELE+ F    Y     R E+A    LTE ++++WF NRR +W+K+
Sbjct: 219 QRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ 277



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 18/45 (40%), Positives = 27/45 (60%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELE+ F    Y     R E+A    LTE ++++WF NRR +W+K+
Sbjct: 233 ELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ 277



>gi|8134640|sp|O14813|PHX2A_HUMAN   Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A)
            (Aristaless homeobox protein homolog) (ARIX1 homeodomain
            protein)
          Length = 284

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 1/72 (1%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T  Q  ELE+ F    Y     R E+A  + L+E ++++WFQNRR K++K  +
Sbjct: 91   RRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQER 150

Query: 1109 LKSMSMAAAGGA 1120
              S +  AAG A
Sbjct: 151  AAS-AKGAAGAA 161



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 33/97 (34%), Positives = 51/97 (52%), Gaps = 1/97 (1%)

Query: 260 SDLAKGACDKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNR 319
           S+ A GA  +  + A + A   NF   P        ++R R T+T  Q  ELE+ F    
Sbjct: 55  SNCALGAL-RDHQPAPYSAVPYNFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETH 113

Query: 320 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           Y     R E+A  + LTE ++++WFQNRR K++K+ +
Sbjct: 114 YPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQER 150



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELE+ F    Y     R E+A  + LTE ++++WFQNRR K++K+ +  ++   +G  + 
Sbjct: 104 ELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGA-AG 162

Query: 718 AKAGE 722
           AK GE
Sbjct: 163 AKKGE 167



>gi|25009572|sp|Q9NZR4|VSX1_HUMAN   Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner
            nuclear layer homeobox protein) (Homeodomain protein
            RINX)
          Length = 365

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 27/66 (40%), Positives = 37/66 (56%)

Query: 1043 IGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 1102
            +G  + +R RT +T +Q  ELEK F    Y     R  +A    L E +I++WFQNRR K
Sbjct: 159  LGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAK 218

Query: 1103 WKKDNK 1108
            W+K  K
Sbjct: 219  WRKREK 224



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 25/61 (40%), Positives = 34/61 (55%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T +Q  ELEK F    Y     R  +A    L E +I++WFQNRR KW+K  
Sbjct: 164 KRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKRE 223

Query: 356 K 356
           K
Sbjct: 224 K 224



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 21/47 (44%), Positives = 26/47 (55%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELEK F    Y     R  +A    L E +I++WFQNRR KW+K  K
Sbjct: 178 ELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224



>gi|18202099|sp|O60902|SHOX2_HUMAN   Short stature homeobox protein 2 (Paired-related homeobox protein
            SHOT) (Homeobox protein Og12X)
          Length = 331

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 28/74 (37%), Positives = 42/74 (56%), Gaps = 1/74 (1%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK-DN 1107
            +R+RT +T  Q  ELE+ F    Y     R E++  L LSE ++++WFQNRR K +K +N
Sbjct: 141  RRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQEN 200

Query: 1108 KLKSMSMAAAGGAF 1121
            +L    +  A   F
Sbjct: 201  QLHKGVLIGAASQF 214



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 3/72 (4%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q  ELE+ F    Y     R E++  L L+E ++++WFQNRR K +K+ 
Sbjct: 140 QRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ- 198

Query: 356 KDEAQAHQPPLL 367
             E Q H+  L+
Sbjct: 199 --ENQLHKGVLI 208



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 21/63 (33%), Positives = 35/63 (55%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 717
           ELE+ F    Y     R E++  L L+E ++++WFQNRR K +K+   ++     G  S+
Sbjct: 154 ELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQ 213

Query: 718 AKA 720
            +A
Sbjct: 214 FEA 216



>gi|6093787|sp|O75360|PROP1_HUMAN   Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary specific
           homeodomain factor)
          Length = 226

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/103 (32%), Positives = 48/103 (46%), Gaps = 3/103 (2%)

Query: 277 GAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLT 336
           G   + F      R     R+R R T++  Q  +LE  F  N+Y     R  +A    L+
Sbjct: 50  GGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLS 109

Query: 337 ERQIKIWFQNRRMKWKKEHKDEAQ--AH-QPPLLEGNVPELAA 376
           E +I++WFQNRR K +K+ +   Q  AH  P      +PE  A
Sbjct: 110 EARIQVWFQNRRAKQRKQERSLLQPLAHLSPAAFSSFLPESTA 152



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 9/89 (10%)

Query: 1044 GGPEGK-----RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 1098
            GG  G+     R RT ++  Q  +LE  F  N+Y     R  +A    LSE +I++WFQN
Sbjct: 60   GGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQN 119

Query: 1099 RRMKWKKDNKLKSMSMA----AAGGAFRP 1123
            RR K +K  +     +A    AA  +F P
Sbjct: 120  RRAKQRKQERSLLQPLAHLSPAAFSSFLP 148



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 18/47 (38%), Positives = 28/47 (59%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           +LE  F  N+Y     R  +A    L+E +I++WFQNRR K +K+ +
Sbjct: 83  QLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER 129



>gi|6831676|sp|O15266|SHOX_HUMAN   Short stature homeobox protein (Short stature homeobox containing
            protein) (Pseudoautosomal homeobox containing osteogenic
            protein)
          Length = 292

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 24/57 (42%), Positives = 35/57 (61%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            +R+RT +T  Q  ELE+ F    Y     R E++  L LSE ++++WFQNRR K +K
Sbjct: 118  RRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRK 174



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 3/72 (4%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q  ELE+ F    Y     R E++  L L+E ++++WFQNRR K +K+ 
Sbjct: 117 QRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ- 175

Query: 356 KDEAQAHQPPLL 367
             E Q H+  +L
Sbjct: 176 --ENQMHKGVIL 185



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 18/45 (40%), Positives = 28/45 (62%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 702
           ELE+ F    Y     R E++  L L+E ++++WFQNRR K +K+
Sbjct: 131 ELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 175



>gi|12644475|sp|Q99811|PRRX2_HUMAN   Paired mesoderm homeobox protein 2 (PRX-2) (Paired related homeobox
            protein 2)
          Length = 253

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 23/69 (33%), Positives = 39/69 (56%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +   Q   LE+ F    Y     R E+A  + LSE ++++WFQNRR K++++ +
Sbjct: 105  RRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER 164

Query: 1109 LKSMSMAAA 1117
                S +A+
Sbjct: 165  AMLASRSAS 173



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 24/82 (29%), Positives = 42/82 (51%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+   Q   LE+ F    Y     R E+A  + L+E ++++WFQNRR K+++  
Sbjct: 104 QRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNE 163

Query: 356 KDEAQAHQPPLLEGNVPELAAD 377
           +    +    LL+    E A +
Sbjct: 164 RAMLASRSASLLKSYSQEAAIE 185



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 25/87 (28%), Positives = 46/87 (52%), Gaps = 8/87 (9%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG---ED 715
           LE+ F    Y     R E+A  + L+E ++++WFQNRR K+++  + + +++ +      
Sbjct: 119 LERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSY 178

Query: 716 SEAKAGEEPGPTRWVQGEPSDLGPGWL 742
           S+  A E+P     V   P+ L P +L
Sbjct: 179 SQEAAIEQP-----VAPRPTALSPDYL 200



>gi|12644347|sp|P78413|IRX4_HUMAN   Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein
           4) (Homeodomain protein IRXA3)
          Length = 519

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/179 (25%), Positives = 61/179 (34%), Gaps = 43/179 (24%)

Query: 557 NRASYEYGASCFYSDKDLSGASPSGS---GKQRGPGDYLHFSPEQ-QYKPDSSSGQGKAL 612
           N  +Y   AS FYS         SGS   G       Y  + P   QY  D         
Sbjct: 85  NYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGT 144

Query: 613 HDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRR 672
             + A R+ TS +  W+Q                               E   N Y T+ 
Sbjct: 145 RRKNATRETTSTLKAWLQ-------------------------------EHRKNPYPTKG 173

Query: 673 RRIEIANALCLTERQIKIWFQNRRMKWKKENKL--------INSTQPSGEDSEAKAGEE 723
            +I +A    +T  Q+  WF N R + KKENK+         +  +P  E  E + GEE
Sbjct: 174 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEE 232



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 18/149 (12%)

Query: 221 YNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHG--- 277
           + +NS      +   YG G+  YGN    +Y        S        K   G+ HG   
Sbjct: 62  HELNSAAALGVYGGPYG-GSQGYGNY--VTYGSEASAFYS--LNSFDSKDGSGSAHGGLA 116

Query: 278 -AAEANFRI------YPWMRSSGPDRKRGRQTYTRYQTLELE---KEFHFNRYLTRRRRI 327
            AA A +        YP+ R    D    R+  TR  T  L+   +E   N Y T+  +I
Sbjct: 117 PAAAAYYPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKI 176

Query: 328 EIAHALCLTERQIKIWFQNRRMKWKKEHK 356
            +A    +T  Q+  WF N R + KKE+K
Sbjct: 177 MLAIITKMTLTQVSTWFANARRRLKKENK 205



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 1030 YPWMRKL-HISHDNIGGPEGKRARTAYTRYQTLELE---KEFHFNRYLTRRRRIEIAHAL 1085
            YP+   L    +D  G  +    R   TR  T  L+   +E   N Y T+  +I +A   
Sbjct: 123  YPYEPALGQYPYDRYGTMDSGTRRKNATRETTSTLKAWLQEHRKNPYPTKGEKIMLAIIT 182

Query: 1086 CLSERQIKIWFQNRRMKWKKDNKL 1109
             ++  Q+  WF N R + KK+NK+
Sbjct: 183  KMTLTQVSTWFANARRRLKKENKM 206



>gi|7531125|sp|P56915|GSC_HUMAN   Homeobox protein goosecoid
          Length = 252

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 21/63 (33%), Positives = 35/63 (55%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +T  Q   LE  F   +Y     R ++A  + L E ++++WF+NRR KW++  +
Sbjct: 156  RRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKR 215

Query: 1109 LKS 1111
              S
Sbjct: 216  SSS 218



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 19/65 (29%), Positives = 37/65 (56%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R  +T  Q   LE  F   +Y     R ++A  + L E ++++WF+NRR KW+++ 
Sbjct: 155 KRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQK 214

Query: 356 KDEAQ 360
           +  ++
Sbjct: 215 RSSSE 219



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 20/79 (25%), Positives = 39/79 (49%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LE  F   +Y     R ++A  + L E ++++WF+NRR KW+++ +  +    + E    
Sbjct: 170 LENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENAEKWNK 229

Query: 719 KAGEEPGPTRWVQGEPSDL 737
            +  +  P +  +   SDL
Sbjct: 230 TSSSKASPEKREEEGKSDL 248



>gi|6174916|sp|P54821|PRRX1_HUMAN   Paired mesoderm homeobox protein 1 (PRX-1) (Paired related homeobox
           protein 1) (Homeobox protein PHOX1)
          Length = 245

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 20/61 (32%), Positives = 35/61 (57%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+   Q   LE+ F    Y     R ++A  + LTE ++++WFQNRR K+++  
Sbjct: 94  QRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNE 153

Query: 356 K 356
           +
Sbjct: 154 R 154



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 19/60 (31%), Positives = 35/60 (58%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT +   Q   LE+ F    Y     R ++A  + L+E ++++WFQNRR K++++ +
Sbjct: 95   RRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNER 154



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 20/70 (28%), Positives = 37/70 (52%), Gaps = 4/70 (5%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLI----NSTQPSGE 714
           LE+ F    Y     R ++A  + LTE ++++WFQNRR K+++  + +    N++     
Sbjct: 109 LERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSY 168

Query: 715 DSEAKAGEEP 724
             +  A E+P
Sbjct: 169 SGDVTAVEQP 178



>gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN   Zinc finger homeobox protein 2
          Length = 1427

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 2/75 (2%)

Query: 1046 PEGKR-ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            P G+R +RT +T +QT  L+  F  + Y        +A  L L+ R + +WFQN R K +
Sbjct: 447  PAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKAR 506

Query: 1105 KDNKLKSMSMAAAGG 1119
            K N  +  SM   GG
Sbjct: 507  K-NACEGGSMPTGGG 520



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 19/58 (32%), Positives = 28/58 (48%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           R+  R  +T +QT  L+  F  + Y        +A  L L  R + +WFQN R K +K
Sbjct: 450 RRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASLLGLASRVVVVWFQNARQKARK 507



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 1044 GGPEG---KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRR 1100
            G P+G   +R RT  +  Q   ++  +   R  T +    +   + L +R I++WFQN R
Sbjct: 913  GVPDGMGQRRYRTQMSSLQLKIMKACYEAYRTPTMQECEVLGEEIGLPKRVIQVWFQNAR 972

Query: 1101 MKWKKDNKLKSMSMAAAGGA 1120
             K KK  KL+  +  + GG+
Sbjct: 973  AKEKK-AKLQGTAAGSTGGS 991



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 5/67 (7%)

Query: 1044 GGPEGKRARTAYTRYQTLELEKEFHFNRYL-----TRRRRIEIAHALCLSERQIKIWFQN 1098
            GG EG+  R    R   L  + E  +  Y+     TR+    I+  + L +R +++WFQN
Sbjct: 703  GGGEGEPPRDKRLRTTILPEQLEILYRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQN 762

Query: 1099 RRMKWKK 1105
             R + +K
Sbjct: 763  TRARERK 769



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 677 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 721
           +A+ L L  R + +WFQN R K +K N     + P+G  +   +G
Sbjct: 483 LASLLGLASRVVVVWFQNARQKARK-NACEGGSMPTGGGTGGASG 526



>gi|37537987|sp|Q9BQY4|PEP2_HUMAN   Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1)
          Length = 288

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 2/131 (1%)

Query: 576 GASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSC 635
           G    G G+++  G      P   ++ D     G   + E +D+    P   + +   + 
Sbjct: 68  GEEKDGGGEEKDGGGA--GVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAV 125

Query: 636 AGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNR 695
            G   G+               ELE+ F   ++ +   R  +A ++ +TE  ++IWF+NR
Sbjct: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185

Query: 696 RMKWKKENKLI 706
           R KW++  + +
Sbjct: 186 RAKWRRHQRAL 196



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 4/70 (5%)

Query: 1043 IGGPEGKRART----AYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 1098
            +GG E   A+     A+T  Q  ELE+ F   ++ +   R  +A ++ ++E  ++IWF+N
Sbjct: 125  VGGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFEN 184

Query: 1099 RRMKWKKDNK 1108
            RR KW++  +
Sbjct: 185  RRAKWRRHQR 194



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 18/54 (33%), Positives = 33/54 (61%)

Query: 303 YTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +T  Q  ELE+ F   ++ +   R  +A ++ +TE  ++IWF+NRR KW++  +
Sbjct: 141 FTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQR 194



>gi|6685480|sp|O15499|GSCL_HUMAN   Homeobox protein goosecoid-like (GSC-2)
          Length = 205

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 22/69 (31%), Positives = 36/69 (52%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +R R  ++  Q   LE  F  N+Y     R  +A  + L E ++++WF+NRR KW+ + +
Sbjct: 127 RRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186

Query: 357 DEAQAHQPP 365
             A A   P
Sbjct: 187 ASASARLLP 195



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 21/70 (30%), Positives = 36/70 (51%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            +R RT ++  Q   LE  F  N+Y     R  +A  + L E ++++WF+NRR KW+   +
Sbjct: 127  RRHRTIFSEEQLQALEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186

Query: 1109 LKSMSMAAAG 1118
              + +    G
Sbjct: 187  ASASARLLPG 196



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 16/46 (34%), Positives = 27/46 (58%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           LE  F  N+Y     R  +A  + L E ++++WF+NRR KW+ + +
Sbjct: 141 LEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186



>gi|417425|sp|P32242|OTX1_HUMAN   Homeobox protein OTX1
          Length = 354

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 1036 LHISHDNIGGP----EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQ 1091
            + + H ++G P    + +R RT +TR Q   LE  F   RY     R E+A  + L E +
Sbjct: 22   MDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESR 81

Query: 1092 IKIWFQNRRMKWKKDNK 1108
            +++WF+NRR K ++  +
Sbjct: 82   VQVWFKNRRAKCRQQQQ 98



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 24/77 (31%), Positives = 41/77 (53%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+TR Q   LE  F   RY     R E+A  + L E ++++WF+NRR K +++ 
Sbjct: 38  QRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ 97

Query: 356 KDEAQAHQPPLLEGNVP 372
           +  +     P  + + P
Sbjct: 98  QSGSGTKSRPAKKKSSP 114



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 8/78 (10%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LE  F   RY     R E+A  + L E ++++WF+NRR K +++       Q SG  +++
Sbjct: 53  LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-------QQSGSGTKS 105

Query: 719 K-AGEEPGPTRWVQGEPS 735
           + A ++  P R   G  S
Sbjct: 106 RPAKKKSSPVRESSGSES 123



>gi|417427|sp|P32243|OTX2_HUMAN   Homeobox protein OTX2
          Length = 289

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 4/77 (5%)

Query: 1036 LHISHDNIGGP----EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQ 1091
            + + H ++G P    + +R RT +TR Q   LE  F   RY     R E+A  + L E +
Sbjct: 22   MDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 81

Query: 1092 IKIWFQNRRMKWKKDNK 1108
            +++WF+NRR K ++  +
Sbjct: 82   VQVWFKNRRAKCRQQQQ 98



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 23/68 (33%), Positives = 38/68 (55%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           ++R R T+TR Q   LE  F   RY     R E+A  + L E ++++WF+NRR K +++ 
Sbjct: 38  QRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQ 97

Query: 356 KDEAQAHQ 363
           + +    Q
Sbjct: 98  QQQQNGGQ 105



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LE  F   RY     R E+A  + L E ++++WF+NRR K +++ +     Q  G++   
Sbjct: 53  LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ---QQQNGGQNKVR 109

Query: 719 KAGEEPGPTRWVQGEPSDLG 738
            A ++  P R V  E    G
Sbjct: 110 PAKKKTSPAREVSSESGTSG 129



>gi|47117874|sp|P78415|IRX3_HUMAN   Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein
           3) (Homeodomain protein IRXB1)
          Length = 501

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 46/147 (31%), Positives = 63/147 (42%), Gaps = 15/147 (10%)

Query: 220 LYNVNSPLYQSPFASGYGLGA-DAYGN-LPCASYDQNIPGLCSDLAKGACDKTDEGALHG 277
           L NV S +Y +P+A+     A   YG  LP A+     P L +        K   G  H 
Sbjct: 49  LSNVLSSVYGAPYAAAAAAAAAQGYGAFLPYAAELPIFPQLGAQYEL----KDSPGVQHP 104

Query: 278 AAEANF-----RIYPWMRSSGPDRKRGRQTYTRYQTLELE---KEFHFNRYLTRRRRIEI 329
           AA A F       YP+ +    D  R +   TR  T  L+    E   N Y T+  +I +
Sbjct: 105 AAAAAFPHPHPAFYPYGQYQFGDPSRPKNA-TRESTSTLKAWLNEHRKNPYPTKGEKIML 163

Query: 330 AHALCLTERQIKIWFQNRRMKWKKEHK 356
           A    +T  Q+  WF N R + KKE+K
Sbjct: 164 AIITKMTLTQVSTWFANARRRLKKENK 190



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 662 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLI-----------NSTQ 710
           E   N Y T+  +I +A    +T  Q+  WF N R + KKENK+            N+  
Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYG 207

Query: 711 PSGEDSEAKAGEEPGPTRWVQGEPSDLG 738
              E+ + +  EE G  R ++ E  +LG
Sbjct: 208 SEREEEDEEEDEEDG-KRELELEEEELG 234



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 1056 TRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 1109
            TR  T  L+    E   N Y T+  +I +A    ++  Q+  WF N R + KK+NK+
Sbjct: 135  TRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKM 191



>gi|47117872|sp|P78412|IRX6_HUMAN   Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein
           6) (Homeodomain protein IRXB3)
          Length = 445

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 1/63 (1%)

Query: 662 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ-PSGEDSEAKA 720
           E   N Y T+  +I +A    +T  Q+  WF N R + KKENK+  + +   GE+ +A+ 
Sbjct: 167 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEG 226

Query: 721 GEE 723
           GEE
Sbjct: 227 GEE 229



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 6/86 (6%)

Query: 1030 YPWMRKL-HISHDNIGGPE--GKRARTAYTRYQTLELE---KEFHFNRYLTRRRRIEIAH 1083
            YP+ R L    ++  G  E  G   R   TR  T  L+    E   N Y T+  +I +A 
Sbjct: 125  YPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAI 184

Query: 1084 ALCLSERQIKIWFQNRRMKWKKDNKL 1109
               ++  Q+  WF N R + KK+NK+
Sbjct: 185  ITKMTLTQVSTWFANARRRLKKENKM 210



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 39/151 (25%), Positives = 57/151 (37%), Gaps = 32/151 (21%)

Query: 227 LYQSPFASGYGLGADAY-GNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRI 285
           +Y +P+A+     A +Y G LP   Y    P L   L      K   G+   +       
Sbjct: 70  IYGAPYAAA--AAAQSYPGYLP---YSPEPPSLYGALNPQYEFKEAAGSFTSSLAQPGAY 124

Query: 286 YPWMRSSGPDRKRGRQTYTRYQTLELE--------------------KEFHFNRYLTRRR 325
           YP+      +R  G+  Y RY  +EL                      E   N Y T+  
Sbjct: 125 YPY------ERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGE 178

Query: 326 RIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           +I +A    +T  Q+  WF N R + KKE+K
Sbjct: 179 KIMLAIITKMTLTQVSTWFANARRRLKKENK 209



>gi|37537960|sp|Q8NHV9|PEPP1_HUMAN   Paired-like homeobox protein PEPP-1 (Ovary-, testis- and
           epididymis-expressed gene protein)
          Length = 184

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 19/64 (29%), Positives = 36/64 (56%)

Query: 300 RQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEA 359
           R  +T  Q  ELE  F   +Y     R E+A  L +TE ++++WF+N+R + ++  ++  
Sbjct: 107 RTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELM 166

Query: 360 QAHQ 363
            A++
Sbjct: 167 LANE 170



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 18/57 (31%), Positives = 33/57 (57%)

Query: 1052 RTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            RT +T  Q  ELE  F   +Y     R E+A  L ++E ++++WF+N+R + ++  +
Sbjct: 107  RTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQR 163



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 15/47 (31%), Positives = 28/47 (59%)

Query: 658 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           ELE  F   +Y     R E+A  L +TE ++++WF+N+R + ++  +
Sbjct: 117 ELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQR 163



>gi|47117908|sp|Q9BZI1|IRX2_HUMAN   Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein
           2) (Homeodomain protein IRXA2)
          Length = 471

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 20/61 (32%), Positives = 31/61 (50%)

Query: 662 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 721
           E   N Y T+  +I +A    +T  Q+  WF N R + KKENK+  + +   ED +   G
Sbjct: 135 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEG 194

Query: 722 E 722
           +
Sbjct: 195 D 195



 Score = 35.8 bits (81), Expect = 0.087
 Identities = 37/135 (27%), Positives = 55/135 (40%), Gaps = 24/135 (17%)

Query: 225 SPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFR 284
           SPL  S  A+    G  +Y   P   YD +  G+   ++            +G+A     
Sbjct: 64  SPLQYSADAAAAAAGFPSYMGAP---YDAHTTGMTGAISYHP---------YGSAA---- 107

Query: 285 IYPWMRSSGPDRKRGRQTYTRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLTERQIK 341
            YP+  +    RK      TR  T  L+    E   N Y T+  +I +A    +T  Q+ 
Sbjct: 108 -YPYQLNDPAYRKNA----TRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVS 162

Query: 342 IWFQNRRMKWKKEHK 356
            WF N R + KKE+K
Sbjct: 163 TWFANARRRLKKENK 177



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 1066 EFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 1109
            E   N Y T+  +I +A    ++  Q+  WF N R + KK+NK+
Sbjct: 135  EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKM 178



>gi|47117871|sp|P78411|IRX5_HUMAN   Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein
           5) (Homeodomain protein IRXB2) (IRX-2A)
          Length = 482

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 45/189 (23%), Positives = 61/189 (32%), Gaps = 12/189 (6%)

Query: 540 TYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQ 599
           +Y     YQ S S+   +  +Y           +L G S SGS      G     +P   
Sbjct: 2   SYPQGYLYQPSASLALYSCPAYSTSVISGPRTDEL-GRSSSGSAFSPYAGSTAFTAPSPG 60

Query: 600 YKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGA----------VYGSHXXXXXX 649
           Y      G   A     A   Y    Y     M    G            YG        
Sbjct: 61  YNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNA 120

Query: 650 XXXXXXXLELE-KEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINS 708
                  L+    E   N Y T+  +I +A    +T  Q+  WF N R + KKENK+  +
Sbjct: 121 TRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWT 180

Query: 709 TQPSGEDSE 717
            +   ED E
Sbjct: 181 PRNRSEDEE 189



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

Query: 300 RQTYTRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           R+  TR  T  L+    E   N Y T+  +I +A    +T  Q+  WF N R + KKE+K
Sbjct: 117 RKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENK 176



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/44 (34%), Positives = 24/44 (54%)

Query: 1066 EFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 1109
            E   N Y T+  +I +A    ++  Q+  WF N R + KK+NK+
Sbjct: 134  EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKM 177



>gi|28202257|sp|P14859|PO2F1_HUMAN   POU domain, class 2, transcription factor 1 (Octamer-binding
           transcription factor 1) (Oct-1) (OTF-1) (NF-A1)
          Length = 743

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 4/77 (5%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
           LEK F  N+  T      IA+ L + +  I++WF NRR K K+    IN     G  S  
Sbjct: 394 LEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR----INPPSSGGTSSSP 449

Query: 719 KAGEEPGPTRWVQGEPS 735
                P PT  V   PS
Sbjct: 450 IKAIFPSPTSLVATTPS 466



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 4/70 (5%)

Query: 1042 NIGGPEG----KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQ 1097
            N  G EG    ++ RT+      + LEK F  N+  T      IA  L + +  I++WF 
Sbjct: 369  NSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFC 428

Query: 1098 NRRMKWKKDN 1107
            NRR K K+ N
Sbjct: 429  NRRQKEKRIN 438



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 19/58 (32%), Positives = 29/58 (50%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           R++ R +      + LEK F  N+  T      IA  L + +  I++WF NRR K K+
Sbjct: 379 RRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKR 436



>gi|123402|sp|P09086|PO2F2_HUMAN   POU domain, class 2, transcription factor 2 (Octamer-binding
            transcription factor 2) (Oct-2) (OTF-2)
            (Lymphoid-restricted immunoglobulin octamer binding
            protein NF-A2)
          Length = 479

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 1/82 (1%)

Query: 1038 ISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQ 1097
            +  D + G   K+ RT+        LEK F  N+  T    + IA  L + +  I++WF 
Sbjct: 288  LGFDGLPGRRRKK-RTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFC 346

Query: 1098 NRRMKWKKDNKLKSMSMAAAGG 1119
            NRR K K+ N   +  M  + G
Sbjct: 347  NRRQKEKRINPCSAAPMLPSPG 368



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 1/61 (1%)

Query: 294 PDRKRGRQTYTRYQT-LELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 352
           P R+R ++T         LEK F  N+  T    + IA  L + +  I++WF NRR K K
Sbjct: 294 PGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEK 353

Query: 353 K 353
           +
Sbjct: 354 R 354



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 18/45 (40%), Positives = 25/45 (55%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 703
           LEK F  N+  T    + IA  L + +  I++WF NRR K K+ N
Sbjct: 312 LEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRIN 356



>gi|18202510|sp|Q15911|ATBF1_HUMAN   Alpha-fetoprotein enhancer binding protein (AT motif-binding factor)
            (AT-binding transcription factor 1)
          Length = 3703

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)

Query: 1044 GGPE---GKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRR 1100
            GG E    KR RT  T  Q   L +++  +   TR+    IAH + L +R +++WFQN R
Sbjct: 2634 GGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTR 2693

Query: 1101 MKWKK 1105
             + +K
Sbjct: 2694 ARERK 2698



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 19/65 (29%), Positives = 34/65 (52%)

Query: 296  RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
            ++  R  +T YQ   L+  F  N Y       ++++ L L  R I +WFQN R K +K +
Sbjct: 2242 KRSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNY 2301

Query: 356  KDEAQ 360
            +++ +
Sbjct: 2302 ENQGE 2306



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 22/141 (15%)

Query: 245  NLPCASYDQNIPGLCSDLAKGACDKTDEGA-------------LHGAAEANFRIYPWMRS 291
            ++P   +D + P L S L  GA  +    +             L    E      P    
Sbjct: 2571 DMPFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGEND 2630

Query: 292  SG-----PDR-KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQ 345
            SG     P R KR R T T  Q   L +++  +   TR+    IAH + L +R +++WFQ
Sbjct: 2631 SGTGGEEPQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQ 2690

Query: 346  NRRMKWKK---EHKDEAQAHQ 363
            N R + +K        AQAH+
Sbjct: 2691 NTRARERKGQFRAVGPAQAHR 2711



 Score = 37.4 bits (85), Expect = 0.030
 Identities = 20/58 (34%), Positives = 31/58 (53%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            + +RT +T YQ   L+  F  N Y       ++++ L L  R I +WFQN R K +K+
Sbjct: 2243 RSSRTRFTDYQLRVLQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKN 2300



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 23/67 (34%), Positives = 33/67 (49%)

Query: 1039 SHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 1098
            S D+   P  KR RT  T  Q   L+  F+  R  T      + + + L +R +++WFQN
Sbjct: 2937 SGDSGDRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQN 2996

Query: 1099 RRMKWKK 1105
             R K KK
Sbjct: 2997 ARAKEKK 3003



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 20/60 (33%), Positives = 30/60 (50%)

Query: 294  PDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
            P +KR R   T  Q   L+  F+  R  T      + + + L +R +++WFQN R K KK
Sbjct: 2944 PGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAKEKK 3003



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 20/62 (32%), Positives = 30/62 (48%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            + KR RT  T  Q   L + F  N   +  +  E+A    L ++ IK WF+N   K ++ 
Sbjct: 2144 QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQR 2203

Query: 1107 NK 1108
            NK
Sbjct: 2204 NK 2205



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 4/61 (6%)

Query: 659  LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 718
            L+  F  N Y       +++N L L  R I +WFQN R K +K  +     Q  G+D E 
Sbjct: 2257 LQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYE----NQGEGKDGER 2312

Query: 719  K 719
            +
Sbjct: 2313 R 2313



 Score = 30.4 bits (67), Expect = 3.7
 Identities = 19/61 (31%), Positives = 29/61 (47%)

Query: 297  KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
            KR R   T  Q   L + F  N   +  +  E+A    L ++ IK WF+N   K ++ +K
Sbjct: 2146 KRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205

Query: 357  D 357
            D
Sbjct: 2206 D 2206



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 5/45 (11%)

Query: 662  EFHFNRYL-----TRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
            E  + +YL     TR+    IA+ + L +R +++WFQN R + +K
Sbjct: 2654 EILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK 2698



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 8/48 (16%)

Query: 677  IANALCLTERQIKIWFQNRRMKWKKENKL-------INSTQPSGEDSE 717
            + N + L +R +++WFQN R K +K++KL       IN T   G  +E
Sbjct: 2979 LGNDIGLPKRVVQVWFQNARAK-EKKSKLSMAKHFGINQTSYEGPKTE 3025



>gi|27923801|sp|Q8TE12|LMX1A_HUMAN   LIM homeobox transcription factor 1 alpha (LIM/homeobox protein
            LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1)
          Length = 382

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 21/57 (36%), Positives = 29/57 (50%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            KR RT  T  Q    +  F  +    R+ R  +A    LS R +++WFQN+R K KK
Sbjct: 196  KRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 14/119 (11%)

Query: 252 DQNIPGLCSDLAKGACDKTDEGAL----HGAAEANFRIYPWMRSSGPDRKRG---RQTYT 304
           ++ +  L S  A  +    DE +L    HGA +            G D KR    R   T
Sbjct: 151 ERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGT-------AEEGKDHKRPKRPRTILT 203

Query: 305 RYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQ 363
             Q    +  F  +    R+ R  +A    L+ R +++WFQN+R K KK  + + Q  Q
Sbjct: 204 TQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQ 262



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 4/111 (3%)

Query: 671 RRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE--AKAGEEPGPTR 728
           R+ R  +A    L+ R +++WFQN+R K KK  +     Q   ++++  + A    G + 
Sbjct: 222 RKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSA 281

Query: 729 WVQGEPSDLGPGWLEEPDPVMKIFQAGYVSKSNRKLMTRKPYSHERKIDYG 779
            ++G  +      L  P  ++ I Q+ Y S   R+ +T      +    YG
Sbjct: 282 GMEGIMNPYTA--LPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYG 330



>gi|8247930|sp|O60663|LMX1B_HUMAN   LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B)
            (LIM-homeobox protein 1.2) (LMX-1.2)
          Length = 379

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 21/57 (36%), Positives = 29/57 (50%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            KR RT  T  Q    +  F  +    R+ R  +A    LS R +++WFQN+R K KK
Sbjct: 197  KRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 4/86 (4%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R   T  Q    +  F  +    R+ R  +A    L+ R +++WFQN+R K KK   
Sbjct: 197 KRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK--- 253

Query: 357 DEAQAHQPPLLEGNVPELAADLWRPR 382
             A+ HQ    + N   L  ++   R
Sbjct: 254 -LARRHQQQQEQQNSQRLGQEVLSSR 278



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 13/31 (41%), Positives = 20/31 (64%)

Query: 671 RRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           R+ R  +A    L+ R +++WFQN+R K KK
Sbjct: 223 RKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253



>gi|12643415|sp|Q9UBR4|LHX3_HUMAN   LIM/homeobox protein Lhx3
          Length = 397

 Score = 37.7 bits (86), Expect = 0.023
 Identities = 22/68 (32%), Positives = 34/68 (50%)

Query: 290 RSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRM 349
           R +    KR R T T  Q   L+  ++ +    R  R +++    L  R +++WFQNRR 
Sbjct: 151 REAEATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRA 210

Query: 350 KWKKEHKD 357
           K K+  KD
Sbjct: 211 KEKRLKKD 218



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 20/60 (33%), Positives = 31/60 (51%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            KR RT  T  Q   L+  ++ +    R  R +++    L  R +++WFQNRR K K+  K
Sbjct: 158  KRPRTTITAKQLETLKSAYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 671 RRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           R  R ++++   L  R +++WFQNRR K K+  K
Sbjct: 184 RHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217



>gi|8247936|sp|P50458|LHX2_HUMAN   LIM/homeobox protein Lhx2 (Homeobox protein LH-2)
          Length = 406

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 16/58 (27%), Positives = 33/58 (56%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            KR RT++  +Q   ++  F  N     +   ++A    L++R +++WFQN R K++++
Sbjct: 267  KRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 324



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 17/62 (27%), Positives = 32/62 (51%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           S    KR R ++  +Q   ++  F  N     +   ++A    LT+R +++WFQN R K+
Sbjct: 262 SSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKF 321

Query: 352 KK 353
           ++
Sbjct: 322 RR 323



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 15/52 (28%), Positives = 28/52 (53%), Gaps = 1/52 (1%)

Query: 676 EIANALCLTERQIKIWFQNRRMKWKKE-NKLINSTQPSGEDSEAKAGEEPGP 726
           ++A    LT+R +++WFQN R K+++   +  N+      D+  + G   GP
Sbjct: 298 QLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGP 349



>gi|730281|sp|P40426|PBX3_HUMAN   Pre-B-cell leukemia transcription factor-3 (Homeobox protein PBX3)
          Length = 434

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 289 MRSSGPDRKRGRQTYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +RS   D +R R+ +++  T  L + F+    N Y +   + E+A    +T  Q+  WF 
Sbjct: 228 LRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFG 287

Query: 346 NRRMKWKK 353
           N+R+++KK
Sbjct: 288 NKRIRYKK 295



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            + +R R  +++  T  L + F+    N Y +   + E+A    ++  Q+  WF N+R+++
Sbjct: 234  DARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRY 293

Query: 1104 KKD 1106
            KK+
Sbjct: 294  KKN 296



 Score = 30.4 bits (67), Expect = 3.7
 Identities = 12/36 (33%), Positives = 21/36 (58%)

Query: 666 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           N Y +   + E+A    +T  Q+  WF N+R+++KK
Sbjct: 260 NPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK 295



>gi|12643346|sp|Q9NQ69|LHX9_HUMAN   LIM/homeobox protein Lhx9
          Length = 388

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 16/58 (27%), Positives = 33/58 (56%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 1106
            KR RT++  +Q   ++  F  N     +   ++A    L++R +++WFQN R K++++
Sbjct: 259  KRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRN 316



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 16/57 (28%), Positives = 31/57 (54%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           KR R ++  +Q   ++  F  N     +   ++A    LT+R +++WFQN R K+++
Sbjct: 259 KRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR 315



>gi|8134548|sp|Q9UPM6|LHX61_HUMAN   LIM/homeobox protein Lhx6.1 (Lhx6)
          Length = 363

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 20/57 (35%), Positives = 32/57 (56%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            KRART++T  Q   ++ +F  +     +   ++A    LS R I++WFQN R + KK
Sbjct: 220  KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 276



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/57 (29%), Positives = 30/57 (52%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           KR R ++T  Q   ++ +F  +     +   ++A    L+ R I++WFQN R + KK
Sbjct: 220 KRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK 276



>gi|18202938|sp|Q9H2C1|LHX5_HUMAN   LIM/homeobox protein Lhx5
          Length = 402

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 22/64 (34%), Positives = 32/64 (50%)

Query: 290 RSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRM 349
           ++SG  R+  R T    Q   L+  F      TR  R ++A    L  R I++WFQNRR 
Sbjct: 174 QNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRS 233

Query: 350 KWKK 353
           K ++
Sbjct: 234 KERR 237



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/68 (30%), Positives = 34/68 (50%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G + +  RT     Q   L+  F      TR  R ++A    L+ R I++WFQNRR K +
Sbjct: 177  GTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKER 236

Query: 1105 KDNKLKSM 1112
            +  +L ++
Sbjct: 237  RMKQLSAL 244



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 15/36 (41%), Positives = 22/36 (61%)

Query: 670 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 705
           TR  R ++A    L  R I++WFQNRR K ++  +L
Sbjct: 206 TRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQL 241



>gi|1352729|sp|P40425|PBX2_HUMAN   Pre-B-cell leukemia transcription factor-2 (Homeobox protein PBX2)
           (G17 protein)
          Length = 430

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 289 MRSSGPDRKRGRQTYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +RS   D +R R+ +++  T  L + F+    N Y +   + E+A    +T  Q+  WF 
Sbjct: 237 LRSRFLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFG 296

Query: 346 NRRMKWKK 353
           N+R+++KK
Sbjct: 297 NKRIRYKK 304



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            + +R R  +++  T  L + F+    N Y +   + E+A    ++  Q+  WF N+R+++
Sbjct: 243  DARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY 302

Query: 1104 KKD 1106
            KK+
Sbjct: 303  KKN 305



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 12/36 (33%), Positives = 21/36 (58%)

Query: 666 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           N Y +   + E+A    +T  Q+  WF N+R+++KK
Sbjct: 269 NPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304



>gi|47117873|sp|P78414|IRX1_HUMAN   Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein
           1) (Homeodomain protein IRXA1)
          Length = 480

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 662 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 721
           E   N Y T+  +I +A    +T  Q+  WF N R + KKENK+    +   ++  A  G
Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFG 207

Query: 722 E--EPGPTRWVQGEPSDL 737
              E  P +    E  DL
Sbjct: 208 SDTEGDPEKAEDDEEIDL 225



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 4/74 (5%)

Query: 286 YPWMRSSGPDRKRGRQTYTRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLTERQIKI 342
           YP+ +    D  R +   TR  T  L+    E   N Y T+  +I +A    +T  Q+  
Sbjct: 118 YPYGQFQYGDPGRPKNA-TRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVST 176

Query: 343 WFQNRRMKWKKEHK 356
           WF N R + KKE+K
Sbjct: 177 WFANARRRLKKENK 190



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 3/57 (5%)

Query: 1056 TRYQTLELE---KEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKL 1109
            TR  T  L+    E   N Y T+  +I +A    ++  Q+  WF N R + KK+NK+
Sbjct: 135  TRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKV 191



>gi|28201884|sp|P78424|PO6F2_HUMAN   POU domain, class 6, transcription factor 2 (Retina-derived
           POU-domain factor-1) (RPF-1)
          Length = 684

 Score = 36.6 bits (83), Expect = 0.051
 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 2/74 (2%)

Query: 292 SGPDRKRGRQTYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           S P +KR R+T    Q LE L   F  N + + +   EIA  L      +++WF N+R  
Sbjct: 595 SEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQA 654

Query: 351 WKKEHKDEAQAHQP 364
            K   K   + H+P
Sbjct: 655 LKNTIK-RLKQHEP 667



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 2/74 (2%)

Query: 1046 PEGKRARTAYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            P  KR R      Q LE L   F  N + + +   EIA  L      +++WF N+R   K
Sbjct: 597  PSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALK 656

Query: 1105 KD-NKLKSMSMAAA 1117
                +LK    A A
Sbjct: 657  NTIKRLKQHEPATA 670



>gi|20138668|sp|Q969G2|LHX4_HUMAN   LIM/homeobox protein Lhx4
          Length = 367

 Score = 36.2 bits (82), Expect = 0.067
 Identities = 21/61 (34%), Positives = 31/61 (50%)

Query: 297 KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHK 356
           KR R T T  Q   L+  +  +    R  R +++    L  R +++WFQNRR K K+  K
Sbjct: 135 KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 194

Query: 357 D 357
           D
Sbjct: 195 D 195



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 20/60 (33%), Positives = 30/60 (50%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            KR RT  T  Q   L+  +  +    R  R +++    L  R +++WFQNRR K K+  K
Sbjct: 135  KRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 194



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 13/34 (38%), Positives = 21/34 (61%)

Query: 671 RRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 704
           R  R ++++   L  R +++WFQNRR K K+  K
Sbjct: 161 RHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 194



>gi|20141754|sp|P41778|PBX1_MOUSE   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
 gi|730279|sp|P40424|PBX1_HUMAN   Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1)
           (Homeobox protein PRL)
          Length = 430

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 289 MRSSGPDRKRGRQTYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +RS   D +R R+ + +  T  L + F+    N Y +   + E+A    +T  Q+  WF 
Sbjct: 226 LRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFG 285

Query: 346 NRRMKWKK 353
           N+R+++KK
Sbjct: 286 NKRIRYKK 293



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            + +R R  + +  T  L + F+    N Y +   + E+A    ++  Q+  WF N+R+++
Sbjct: 232  DARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRY 291

Query: 1104 KKD 1106
            KK+
Sbjct: 292  KKN 294



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 12/36 (33%), Positives = 21/36 (58%)

Query: 666 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 701
           N Y +   + E+A    +T  Q+  WF N+R+++KK
Sbjct: 258 NPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293



>gi|37999770|sp|Q9BYU1|PBX4_HUMAN   Pre-B-cell leukemia transcription factor-4 (Homeobox protein PBX4)
          Length = 330

 Score = 35.8 bits (81), Expect = 0.087
 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 289 MRSSGPDRKRGRQTYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLTERQIKIWFQ 345
           +RS   D +R R+ +++  T  L + F+    N Y +   + E+A    LT  Q+  WF 
Sbjct: 159 LRSRLLDARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFG 218

Query: 346 NRRMKWKK 353
           N+R+++KK
Sbjct: 219 NKRIRYKK 226



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHF---NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKW 1103
            + +R R  +++  T  L + F+    N Y +   + E+A    L+  Q+  WF N+R+++
Sbjct: 165  DARRKRRNFSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRY 224

Query: 1104 KKD 1106
            KK+
Sbjct: 225  KKN 227



>gi|60416412|sp|P48742|LHX1_HUMAN   LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein
            Lim-1)
          Length = 406

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 21/68 (30%), Positives = 34/68 (50%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G + +  RT     Q   L+  F      TR  R ++A    L+ R I++WFQNRR K +
Sbjct: 177  GAKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKER 236

Query: 1105 KDNKLKSM 1112
            +  +L ++
Sbjct: 237  RMKQLSAL 244



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 1/59 (1%)

Query: 296 RKRGRQTYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           ++RG +T  + + LE L+  F      TR  R ++A    L  R I++WFQNRR K ++
Sbjct: 179 KRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERR 237



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 15/36 (41%), Positives = 22/36 (61%)

Query: 670 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 705
           TR  R ++A    L  R I++WFQNRR K ++  +L
Sbjct: 206 TRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQL 241



>gi|2495300|sp|Q12837|PO42_HUMAN   POU domain, class 4, transcription factor 2 (Brain-specific
            homeobox/POU domain protein 3B) (Brn-3B)
          Length = 410

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 1032 WMRKLHISH-------DNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 1084
            W+ +   SH       +   G E KR RT+    +   LE  F      +  +   IA  
Sbjct: 323  WLEEAEKSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEK 382

Query: 1085 LCLSERQIKIWFQNRRMKWKK 1105
            L L +  +++WF N+R K K+
Sbjct: 383  LDLKKNVVRVWFCNQRQKQKR 403



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           +G ++KR R +    +   LE  F      +  +   IA  L L +  +++WF N+R K 
Sbjct: 342 NGAEKKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQ 401

Query: 352 KK 353
           K+
Sbjct: 402 KR 403



>gi|12230598|sp|Q9NPC8|SIX2_HUMAN   Homeobox protein SIX2 (Sine oculis homeobox homolog 2)
          Length = 291

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 28/99 (28%), Positives = 39/99 (39%), Gaps = 10/99 (10%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWK---------KENKLINST 709
           L + +  N Y + R + E+A A  LT  Q+  WF+NRR + +          EN   NS 
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSH 198

Query: 710 QP-SGEDSEAKAGEEPGPTRWVQGEPSDLGPGWLEEPDP 747
            P +G         E   T     + S   P  L  P P
Sbjct: 199 NPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPP 237



 Score = 32.7 bits (73), Expect = 0.74
 Identities = 16/53 (30%), Positives = 28/53 (52%)

Query: 311 LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQ 363
           L + +  N Y + R + E+A A  LT  Q+  WF+NRR + +     E + ++
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNE 191



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 15/56 (26%), Positives = 27/56 (48%)

Query: 1047 EGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 1102
            +G+     +       L + +  N Y + R + E+A A  L+  Q+  WF+NRR +
Sbjct: 123  DGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178



>gi|28201861|sp|Q9UKI9|PO2F3_HUMAN   POU domain, class 2, transcription factor 3 (Octamer-binding
           transcription factor 11) (Oct-11) (Transcription factor
           Skn-1) (PLA-1 protein)
          Length = 436

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 296 RKRGRQTYTRYQT-LELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE 354
           RKR ++T       L LEK F  N   +      IA  L + +  +++WF NRR K K+ 
Sbjct: 280 RKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRI 339

Query: 355 HKDEAQAHQPPL 366
           +   A   +PP+
Sbjct: 340 NCPVATPIKPPV 351



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 19/59 (32%), Positives = 29/59 (49%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN 1107
            ++ RT+      L LEK F  N   +      IA  L + +  +++WF NRR K K+ N
Sbjct: 282  RKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN 340



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 17/47 (36%), Positives = 24/47 (51%)

Query: 657 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 703
           L LEK F  N   +      IA  L + +  +++WF NRR K K+ N
Sbjct: 294 LTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN 340



>gi|2495306|sp|Q14863|PO6F1_HUMAN   POU domain, class 6, transcription factor 1 (mPOU homeobox protein)
            (Brain-specific homeobox/POU domain protein 5) (Brain-5)
            (Brn-5 protein)
          Length = 301

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 1/67 (1%)

Query: 1044 GGPEGKRAR-TAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 1102
            G P  KR R T++T      L   F  N   T +   EIA  L      +++WF NRR  
Sbjct: 229  GEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQT 288

Query: 1103 WKKDNKL 1109
             K  +KL
Sbjct: 289  LKNTSKL 295



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 1/64 (1%)

Query: 294 PDRKRGRQTYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 352
           P +KR R+T    Q +E L   F  N   T +   EIA  L      +++WF NRR   K
Sbjct: 231 PSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLK 290

Query: 353 KEHK 356
              K
Sbjct: 291 NTSK 294



>gi|37999860|sp|O14686|MLL2_HUMAN   Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related
            protein)
          Length = 5262

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 7/73 (9%)

Query: 697  MKWKKENKLINSTQPSGEDSEAKAGEEPGP---TRWVQGEPSDLGPGWLEEPDPVMKIFQ 753
            MK     +++    P+   +E K GE  GP    + ++G+  D GP WL++ D V+    
Sbjct: 4534 MKIPNSYEVLFPESPARGGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL---- 4589

Query: 754  AGYVSKSNRKLMT 766
            AGY  K    +++
Sbjct: 4590 AGYTLKRQLDILS 4602



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query: 218  PGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLC 259
            PGL    +PL Q PF  G GL     GNLP +S   + PGLC
Sbjct: 1637 PGLEGSRTPL-QRPFLQG-GL---PLGNLPSSSPMDSYPGLC 1673



>gi|2495302|sp|Q15319|PO43_HUMAN   POU domain, class 4, transcription factor 3 (Brain-specific
            homeobox/POU domain protein 3C) (Brn-3C)
          Length = 338

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 19/61 (31%), Positives = 29/61 (47%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G E KR RT+    +   LE  F      +  +   IA  L L +  +++WF N+R K K
Sbjct: 271  GSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 330

Query: 1105 K 1105
            +
Sbjct: 331  R 331



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 18/62 (29%), Positives = 30/62 (48%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           +G +RKR R +    +   LE  F      +  +   IA  L L +  +++WF N+R K 
Sbjct: 270 NGSERKRKRTSIAAPEKRSLEAYFAIQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQ 329

Query: 352 KK 353
           K+
Sbjct: 330 KR 331



>gi|12230612|sp|Q9UIU6|SIX4_HUMAN   Homeobox protein SIX4 (Sine oculis homeobox homolog 4)
          Length = 760

 Score = 34.3 bits (77), Expect = 0.25
 Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK----ENKLINSTQPSGE 714
           L++ +  NRY +   +  +A    L+  Q+  WF+NRR + +     ++K  +   PS E
Sbjct: 217 LKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTE 276

Query: 715 DSEAKAGEEPGP 726
           D  +K  E+  P
Sbjct: 277 DESSKGHEDLSP 288



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 15/51 (29%), Positives = 28/51 (54%)

Query: 1063 LEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMS 1113
            L++ +  NRY +   +  +A    LS  Q+  WF+NRR + +  ++ +S S
Sbjct: 217  LKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKS 267



>gi|20978495|sp|Q96A47|ISL2_HUMAN   Insulin gene enhancer protein ISL-2 (Islet-2)
          Length = 359

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 12/91 (13%)

Query: 1031 PWMRKLHISHDNIGG-----PEGKRARTAYTRYQTLELEKEFHFNR--YLTRRR-----R 1078
            P  R LH+     G      P   +     TR +T+  EK+ H  R  Y    R     +
Sbjct: 162  PGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMK 221

Query: 1079 IEIAHALCLSERQIKIWFQNRRMKWKKDNKL 1109
             ++     LS R I++WFQN+R K KK + L
Sbjct: 222  EQLVEMTGLSPRVIRVWFQNKRCKDKKKSIL 252



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 7/58 (12%)

Query: 304 TRYQTLELEKEFHFNR--YLTRRR-----RIEIAHALCLTERQIKIWFQNRRMKWKKE 354
           TR +T+  EK+ H  R  Y    R     + ++     L+ R I++WFQN+R K KK+
Sbjct: 192 TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKK 249



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 13/28 (46%), Positives = 20/28 (71%)

Query: 683 LTERQIKIWFQNRRMKWKKENKLINSTQ 710
           L+ R I++WFQN+R K KK++ L+   Q
Sbjct: 230 LSPRVIRVWFQNKRCKDKKKSILMKQLQ 257



>gi|2506535|sp|Q01851|PO4F1_HUMAN   POU domain, class 4, transcription factor 1 (Brain-specific
            homeobox/POU domain protein 3A) (Brn-3A) (Oct-T1)
            (Homeobox/POU domain protein RDC-1)
          Length = 423

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 19/61 (31%), Positives = 29/61 (47%)

Query: 1045 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWK 1104
            G E KR RT+    +   LE  F      +  +   IA  L L +  +++WF N+R K K
Sbjct: 356  GGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQK 415

Query: 1105 K 1105
            +
Sbjct: 416  R 416



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 292 SGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW 351
           +G ++KR R +    +   LE  F      +  +   IA  L L +  +++WF N+R K 
Sbjct: 355 NGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQ 414

Query: 352 KK 353
           K+
Sbjct: 415 KR 416



>gi|20141591|sp|Q15811|ITN1_HUMAN   Intersectin 1 (SH3 domain-containing protein 1A) (SH3P17)
          Length = 1721

 Score = 33.1 bits (74), Expect = 0.57
 Identities = 22/91 (24%), Positives = 41/91 (45%)

Query: 268 DKTDEGALHGAAEANFRIYPWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRI 327
           +K  +  L    +   R+    R+    ++R RQ   R + LELEK+    R L R+R  
Sbjct: 366 EKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREE 425

Query: 328 EIAHALCLTERQIKIWFQNRRMKWKKEHKDE 358
           E    +   E   +   + R+++W++  + E
Sbjct: 426 ERRKEIERREAAKRELERQRQLEWERNRRQE 456



>gi|2495290|sp|Q15475|SIX1_HUMAN   Homeobox protein SIX1 (Sine oculis homeobox homolog 1)
          Length = 284

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/40 (37%), Positives = 23/40 (57%)

Query: 659 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 698
           L + +  N Y + R + E+A A  LT  Q+  WF+NRR +
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178



 Score = 32.3 bits (72), Expect = 0.96
 Identities = 15/40 (37%), Positives = 23/40 (57%)

Query: 311 LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 350
           L + +  N Y + R + E+A A  LT  Q+  WF+NRR +
Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/40 (35%), Positives = 23/40 (57%)

Query: 1063 LEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMK 1102
            L + +  N Y + R + E+A A  L+  Q+  WF+NRR +
Sbjct: 139  LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178



>gi|47606423|sp|P61371|ISL1_HUMAN   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606425|sp|P61373|ISL1_MESAU   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606424|sp|P61372|ISL1_MOUSE   Insulin gene enhancer protein ISL-1 (Islet-1)
 gi|47606422|sp|P61374|ISL1_RAT   Insulin gene enhancer protein ISL-1 (Islet-1)
          Length = 349

 Score = 32.3 bits (72), Expect = 0.96
 Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 7/57 (12%)

Query: 1056 TRYQTLELEKEFHFNR--YLTRRR-----RIEIAHALCLSERQIKIWFQNRRMKWKK 1105
            TR +T+  EK+ H  R  Y    R     + ++     LS R I++WFQN+R K KK
Sbjct: 182  TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKK 238



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 9/70 (12%)

Query: 304 TRYQTLELEKEFHFNR--YLTRRR-----RIEIAHALCLTERQIKIWFQNRRMKWKKEH- 355
           TR +T+  EK+ H  R  Y    R     + ++     L+ R I++WFQN+R K KK   
Sbjct: 182 TRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSI 241

Query: 356 -KDEAQAHQP 364
              + Q  QP
Sbjct: 242 MMKQLQQQQP 251



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 12/28 (42%), Positives = 19/28 (67%)

Query: 683 LTERQIKIWFQNRRMKWKKENKLINSTQ 710
           L+ R I++WFQN+R K KK + ++   Q
Sbjct: 220 LSPRVIRVWFQNKRCKDKKRSIMMKQLQ 247



>gi|400659|sp|Q01860|PO5F1_HUMAN   POU domain, class 5, transcription factor 1 (Octamer-binding
           transcription factor 3) (Oct-3) (Oct-4)
          Length = 360

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 22/65 (33%), Positives = 30/65 (46%)

Query: 296 RKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 355
           RKR R +        LE  F      T ++   IA  L L +  +++WF NRR K K+  
Sbjct: 230 RKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSS 289

Query: 356 KDEAQ 360
            D AQ
Sbjct: 290 SDYAQ 294



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 2/75 (2%)

Query: 1049 KRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 1108
            KR RT+        LE  F      T ++   IA  L L +  +++WF NRR K K+ + 
Sbjct: 231  KRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSS 290

Query: 1109 --LKSMSMAAAGGAF 1121
               +     AAG  F
Sbjct: 291  DYAQREDFEAAGSPF 305



>gi|47116024|sp|Q8WXF8|DEDD2_HUMAN   DNA-binding death effector domain-containing protein 2
           (DED-containing protein FLAME-3)
          Length = 326

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 3/85 (3%)

Query: 530 SYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPG 589
           SYG SS   +T  S    +QS+S     +  +E G+      +   G  PSG  ++R  G
Sbjct: 116 SYGTSSSSKRTEGSCRRRRQSSSSANSQQGQWETGSPPTKRQRRSRGR-PSGGARRRRRG 174

Query: 590 DYLHFSPEQQYKPDSSSGQGKALHD 614
                +P+QQ +P   S +GK   D
Sbjct: 175 --APAAPQQQSEPARPSSEGKVTCD 197



>gi|32172435|sp|P46934|NEDD4_HUMAN   E3 ubiquitin-protein ligase Nedd-4
          Length = 1000

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 18/96 (18%)

Query: 696 RMKWKKENKLINSTQPSG-EDSEAKAGEEPGPTRWV-------------QGEPSDLGPGW 741
           R+K     K+    + SG ED  A+  EE  P  WV             Q EPS L PGW
Sbjct: 239 RVKGYLRLKMTYLPKTSGSEDDNAEQAEELEPG-WVVLDQPDAACHLQQQQEPSPLPPGW 297

Query: 742 LEEPDPVMKIFQAGYVSKSNRKLMTRKPYSHERKID 777
            E  D + + +   YV+  +R+   ++P   +   D
Sbjct: 298 EERQDILGRTY---YVNHESRRTQWKRPTPQDNLTD 330



>gi|1709437|sp|Q03052|PO3F1_HUMAN   POU domain, class 3, transcription factor 1 (Octamer-binding
           transcription factor 6) (Oct-6) (POU-domain
           transcription factor SCIP)
          Length = 448

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 15/64 (23%)

Query: 677 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGEEPGPTRWVQGEPSD 736
           +A++L L +  +++WF NRR K K+      +  P  +D  A               P +
Sbjct: 369 LADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYA---------------PGE 413

Query: 737 LGPG 740
           LGPG
Sbjct: 414 LGPG 417



>gi|44888551|sp|Q9UKY1|ZHX1_HUMAN   Zinc fingers and homeoboxes protein 1
          Length = 873

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 4/32 (12%)

Query: 336 TERQIKIWFQNRRMK----WKKEHKDEAQAHQ 363
           TE QIKIWF  +R+K    W  E  +EA+  Q
Sbjct: 324 TEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQ 355



>gi|28201858|sp|Q06416|PO5L_HUMAN   POU domain, class 5, transcription factor 1-like protein 1 (Octamer
           binding protein 3-like)
          Length = 359

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/32 (43%), Positives = 19/32 (59%)

Query: 329 IAHALCLTERQIKIWFQNRRMKWKKEHKDEAQ 360
           IA  L L +  +++WF NRR K K+   D AQ
Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 293



>gi|28201859|sp|Q9BZV7|PO5M_HUMAN   POU domain, class 5, transcription factor 1-like protein 2
          Length = 359

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 14/32 (43%), Positives = 19/32 (59%)

Query: 329 IAHALCLTERQIKIWFQNRRMKWKKEHKDEAQ 360
           IA  L L +  +++WF NRR K K+   D AQ
Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQ 293



>gi|123408|sp|P28069|PIT1_HUMAN   Pituitary-specific positive transcription factor 1 (Pit-1) (Growth
            hormone factor 1) (GHF-1)
          Length = 291

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 1/67 (1%)

Query: 1040 HDNIGGPEGKRARTAYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQN 1098
            ++ +G  E KR R         + LE+ F      + +  + +A  L L +  +++WF N
Sbjct: 205  NEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCN 264

Query: 1099 RRMKWKK 1105
            RR + K+
Sbjct: 265  RRQREKR 271



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 1/60 (1%)

Query: 295 DRKRGRQTYTRYQTLE-LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 353
           +RKR R+T       + LE+ F      + +  + +A  L L +  +++WF NRR + K+
Sbjct: 212 ERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKR 271



>gi|52000732|sp|Q99700|ATX2_HUMAN   Ataxin-2 (Spinocerebellar ataxia type 2 protein)
          Length = 1312

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 510  QECLLGSSEAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFY 569
            Q  L+ SS   Y A     A Y    LP    TSP FY   ++     + ++       +
Sbjct: 1083 QPGLVSSSATQYGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPH 1142

Query: 570  SDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALH 613
            +      A+P+G  + +  G +   SP Q ++  ++    +ALH
Sbjct: 1143 TPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAA----QALH 1182



>gi|44889075|sp|Q9H4I2|ZHX3_HUMAN   Zinc fingers and homeoboxes protein 3 (Triple homeobox 1 protein)
          Length = 956

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 4/67 (5%)

Query: 311 LEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK----WKKEHKDEAQAHQPPL 366
           L+  FH   Y T+     +       E Q+KIWF  +R+K    W  E  ++A+      
Sbjct: 319 LKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNT 378

Query: 367 LEGNVPE 373
           +  +VP+
Sbjct: 379 VIQSVPQ 385



>gi|6094293|sp|O95343|SIX3_HUMAN   Homeobox protein SIX3 (Sine oculis homeobox homolog 3)
          Length = 332

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 9/73 (12%)

Query: 668 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWK---KENKLIN-STQPSGEDSEAKAGEE 723
           Y    ++ E+A A  LT  Q+  WF+NRR + +    +N+L + +  PSG  S A    E
Sbjct: 230 YPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLA----E 285

Query: 724 PG-PTRWVQGEPS 735
           PG PT      PS
Sbjct: 286 PGCPTHGSAESPS 298



>gi|2506534|sp|P20264|PO33_HUMAN   POU domain, class 3, transcription factor 3 (Brain-specific
           homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein)
          Length = 500

 Score = 29.3 bits (64), Expect = 8.2
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 329 IAHALCLTERQIKIWFQNRRMKWKKEHKDEAQAHQPPLLEGNVPELAAD 377
           +A +L L +  +++WF NRR K K+      Q   P  +   V  ++AD
Sbjct: 439 LADSLQLEKEVVRVWFCNRRQKEKRMTPPGIQQQTPDDVYSQVGTVSAD 487






  Database: Non-redundant SwissProt sequences
    Posted date:  Mar 15, 2005 10:11 AM
  Number of letters in database: 60,490,055
  Number of sequences in database:  164,271
  
Lambda     K      H
   0.318    0.133    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,592,845
Number of Sequences: 164271
Number of extensions: 120608
Number of successful extensions: 395
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 301
Number of HSP's gapped (non-prelim): 95
length of query: 1123
length of database: 6,424,444
effective HSP length: 106
effective length of query: 1017
effective length of database: 5,162,514
effective search space: 5250276738
effective search space used: 5250276738
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)