>gi|17378385|sp|P31267|HXA6_HUMAN Homeobox protein Hox-A6 (Hox-1B) Length = 233 Score = 458 bits (1178), Expect = e-130 Identities = 220/233 (94%), Positives = 220/233 (94%) Query: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ 60 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ Sbjct: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ 60 Query: 61 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG 120 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG Sbjct: 61 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG 120 Query: 121 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYL 180 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSH LELEKEFHFNRYL Sbjct: 121 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHGRRGRQTYTRYQTLELEKEFHFNRYL 180 Query: 181 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE Sbjct: 181 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233
>gi|13124738|sp|P17509|HXB6_HUMAN Homeobox protein Hox-B6 (Hox-2B) (Hox-2.2) (HU-2) Length = 224 Score = 209 bits (531), Expect = 8e-55 Identities = 117/235 (49%), Positives = 149/235 (63%), Gaps = 13/235 (5%) Query: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-DALRPFPASYGASSLPDKTYTSPCFYQ 59 MSSYFVN TFP +L SGQ+SFLG +PLY +GY D LR +PA YG DK + + +Y Sbjct: 1 MSSYFVNSTFPVTLASGQESFLGHVPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYP 60 Query: 60 QSNSVLACNRASYEYG-ASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSG 118 + A +YG A FY +K+ S + SG+ +Q F PE + S Sbjct: 61 PAGGGYG-RAAPCDYGPAPAFYREKE-SACALSGADEQPP------FHPEPR---KSDCA 109 Query: 119 QGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNR 178 Q K++ E ++K ++PVYPWMQRMNSC + +G LELEKEFH+NR Sbjct: 110 QDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNR 169 Query: 179 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233 YLTRRRRIEIA+ALCLTERQIKIWFQNRRMKWKKE+KL++++Q S E+ E K E Sbjct: 170 YLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE 224
>gi|20141493|sp|P09630|HXC6_HUMAN Homeobox protein Hox-C6 (Hox-3C) (HHO.C8) (CP25) Length = 235 Score = 181 bits (458), Expect = 2e-46 Identities = 101/229 (44%), Positives = 133/229 (58%), Gaps = 14/229 (6%) Query: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQ 60 M+SYF NP+ L GQD L + L YD +R F ++YGA+ ++ Y++P + Q Sbjct: 1 MNSYFTNPSLSCHLAGGQD-VLPNVALNSTAYDPVRHF-STYGAAVAQNRIYSTPFYSPQ 58 Query: 61 SNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQG 120 N V + +R Y+YG++ FY +KD+ + L + + D SS QG Sbjct: 59 ENVVFSSSRGPYDYGSNSFYQEKDMLSNCRQNT---------LGHNTQTSIAQDFSSEQG 109 Query: 121 KALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYL 180 + D+K + +YPWMQRMNS +G YG+ LELEKEFHFNRYL Sbjct: 110 RTAPQ---DQKASIQIYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL 166 Query: 181 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKE+ L ++ G + A Sbjct: 167 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGGGATA 215
>gi|52788238|sp|P20719|HXA5_HUMAN Homeobox protein Hox-A5 (Hox-1C) Length = 270 Score = 115 bits (288), Expect = 1e-26 Identities = 88/259 (33%), Positives = 117/259 (45%), Gaps = 46/259 (17%) Query: 1 MSSYFVNPTFPGSLPSG------------------QDSFLGQLPLYQAGYDAL------- 35 MSSYFVN +F G P+G +DS Y GY+ + Sbjct: 1 MSSYFVN-SFCGRYPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRS 59 Query: 36 -----------RPFPASYGASSLP-DKTYTSPCFYQQSNSV--LACNRASYEYGASCFYS 81 R + AS AS+ P + Y+ P S L C+ + G+ + Sbjct: 60 GSGHFGSGERARSYAAS--ASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHG 117 Query: 82 DKDL----SGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVY 137 K+ SGAS + + + + +SS Q A + +Y Sbjct: 118 GKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIY 177 Query: 138 PWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTER 197 PWM++++ + G LELEKEFHFNRYLTRRRRIEIA+ALCL+ER Sbjct: 178 PWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSER 237 Query: 198 QIKIWFQNRRMKWKKENKL 216 QIKIWFQNRRMKWKK+NKL Sbjct: 238 QIKIWFQNRRMKWKKDNKL 256
>gi|20141491|sp|P09016|HXD4_HUMAN Homeobox protein Hox-D4 (Hox-4B) (Hox-5.1) (HHO.C13) Length = 255 Score = 111 bits (278), Expect = 2e-25 Identities = 90/247 (36%), Positives = 107/247 (43%), Gaps = 35/247 (14%) Query: 1 MSSYFVN-----PTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSP 55 MSSY VN P FP Q +LG+ G A GA P Y P Sbjct: 3 MSSYMVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGA-------QGADFQPPGLYPRP 55 Query: 56 CFYQQSNSVLACNRASYEYGASCFYSDKDLS----GASPSG-SGKQRGPGDYLHFSPEQQ 110 F +Q +G S L G P G G PG+ P Sbjct: 56 DFGEQP------------FGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPP 103 Query: 111 YKP----DSSSGQGKALHDEGADRKYTSPVYPWMQRM--NSCAGAVYGSHXXXXXXXXXX 164 P + S G K + VYPWM+++ NS G Sbjct: 104 PAPLPGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTR 163 Query: 165 XXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG 224 LELEKEFHFNRYLTRRRRIEIA+ LCL+ERQIKIWFQNRRMKWKK++KL N+ S Sbjct: 164 QQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSS 223 Query: 225 EDSEAKA 231 S + + Sbjct: 224 SSSSSSS 230
>gi|6166217|sp|Q00056|HXA4_HUMAN Homeobox protein Hox-A4 (Hox-1D) (Hox-1.4) Length = 320 Score = 111 bits (278), Expect = 2e-25 Identities = 55/99 (55%), Positives = 67/99 (67%), Gaps = 2/99 (2%) Query: 136 VYPWMQRMNSCA--GAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALC 193 VYPWM++++ A + G LELEKEFHFNRYLTRRRRIEIA+ LC Sbjct: 194 VYPWMKKIHVSAVNPSYNGGEPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLC 253 Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232 L+ERQ+KIWFQNRRMKWKK++KL N+ S + A AG Sbjct: 254 LSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAG 292
>gi|400000|sp|P09067|HXB5_HUMAN Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1) Length = 269 Score = 110 bits (276), Expect = 3e-25 Identities = 92/260 (35%), Positives = 119/260 (45%), Gaps = 49/260 (18%) Query: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGY-------DALRPFPASYG---------- 43 MSSYFVN +F G P+G D QL Y +G D SYG Sbjct: 1 MSSYFVN-SFSGRYPNGPDY---QLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSV 56 Query: 44 ----ASS-----LPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSG 94 ASS + + + P Q+ A + S S ++ D GA PS S Sbjct: 57 NRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASS 116 Query: 95 ---KQRGPGDYLHFS----------PEQQYKPDSSSGQGKALHDE-----GADRKYTSPV 136 + +F+ PE+ SS +A + A T + Sbjct: 117 PSDQATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQI 176 Query: 137 YPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTE 196 +PWM++++ + + G LELEKEFHFNRYLTRRRRIEIA+ALCL+E Sbjct: 177 FPWMRKLH-ISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSE 235 Query: 197 RQIKIWFQNRRMKWKKENKL 216 RQIKIWFQNRRMKWKK+NKL Sbjct: 236 RQIKIWFQNRRMKWKKDNKL 255
>gi|123255|sp|P09629|HXB7_HUMAN Homeobox protein Hox-B7 (Hox-2C) (HHO.C1) Length = 217 Score = 110 bits (275), Expect = 4e-25 Identities = 80/215 (37%), Positives = 100/215 (46%), Gaps = 32/215 (14%) Query: 40 ASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDK-DLSGASPSGSGK--Q 96 + Y ASS + + F +Q++ A N YGA S + G P G G Q Sbjct: 12 SKYPASS---SVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAGSMQGLYPGGGGMAGQ 68 Query: 97 RGPGDY------------LHFSPEQQYKP-----DSSSGQG-KALHDEGADRKYTSPVYP 138 G Y +H +P +Q DS+ G K D + +YP Sbjct: 69 SAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYP 128 Query: 139 WMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQ 198 WM+ G+ LELEKEFH+NRYLTRRRRIEIA+ LCLTERQ Sbjct: 129 WMRSS--------GTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQ 180 Query: 199 IKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233 IKIWFQNRRMKWKKENK + +EA+ E Sbjct: 181 IKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEE 215
>gi|547692|sp|P17483|HXB4_HUMAN Homeobox protein Hox-B4 (Hox-2F) (Hox-2.6) Length = 251 Score = 107 bits (266), Expect = 4e-24 Identities = 55/99 (55%), Positives = 68/99 (68%), Gaps = 2/99 (2%) Query: 136 VYPWMQRMN-SCAGAVY-GSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALC 193 VYPWM++++ S Y G LELEKEFH+NRYLTRRRR+EIA+ALC Sbjct: 141 VYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALC 200 Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232 L+ERQIKIWFQNRRMKWKK++KL N+ SG + + G Sbjct: 201 LSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGG 239
>gi|123279|sp|P09017|HXC4_HUMAN Homeobox protein Hox-C4 (Hox-3E) (CP19) Length = 264 Score = 106 bits (265), Expect = 6e-24 Identities = 71/169 (42%), Positives = 88/169 (52%), Gaps = 25/169 (14%) Query: 80 YSDKDLSGASPSGSGKQRG--PGDYLHFSPEQQY---KPDSSSG-------------QGK 121 Y ++ S S G G RG P H PE+ +P SG Q Sbjct: 62 YPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPA 121 Query: 122 ALHDEGADRKYTSPVYPWMQRMN-SCAGAVY-GSHXXXXXXXXXXXXXLELEKEFHFNRY 179 H A K VYPWM++++ S Y G LELEKEFH+NRY Sbjct: 122 PDHPSSAASKQPI-VYPWMKKIHVSTVNPNYNGGEPKRSRAAYTRQQVLELEKEFHYNRY 180 Query: 180 LTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL----INSTQPSG 224 LTRRRRIEIA++LCL+ERQIKIWFQNRRMKWKK+++L + S P+G Sbjct: 181 LTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAG 229
>gi|3915721|sp|P31268|HXA7_HUMAN Homeobox protein Hox-A7 (Hox-1A) (Hox 1.1) Length = 230 Score = 103 bits (258), Expect = 4e-23 Identities = 80/197 (40%), Positives = 95/197 (48%), Gaps = 30/197 (15%) Query: 40 ASYGASSLPDKTYTSPCFYQQSNSVLACN------RASYEYGASCF-------YSDKDLS 86 +SY ++L K YT+ Q+ +C+ R+ Y GA F Y+ Sbjct: 3 SSYYVNALFSK-YTAGTSLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPL 61 Query: 87 GASPSGSGKQRGPGDY--LHFSPEQQYKPDSSSGQGKAL---HDEGA---DRKYTSPVYP 138 SP SG G Y L + Q P S K DEGA + +YP Sbjct: 62 YQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYP 121 Query: 139 WMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQ 198 WM+ G LELEKEFHFNRYLTRRRRIEIA+ALCLTERQ Sbjct: 122 WMRSS--------GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQ 173 Query: 199 IKIWFQNRRMKWKKENK 215 IKIWFQNRRMKWKKE+K Sbjct: 174 IKIWFQNRRMKWKKEHK 190
>gi|232262|sp|Q00444|HXC5_HUMAN Homeobox protein Hox-C5 (Hox-3D) (CP11) Length = 222 Score = 101 bits (252), Expect = 2e-22 Identities = 48/81 (59%), Positives = 57/81 (70%), Gaps = 4/81 (4%) Query: 136 VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLT 195 +YPWM +++ + + LELEKEFHFNRYLTRRRRIEIAN LCL Sbjct: 140 IYPWMTKLHMS----HETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLN 195 Query: 196 ERQIKIWFQNRRMKWKKENKL 216 ERQIKIWFQNRRMKWKK++K+ Sbjct: 196 ERQIKIWFQNRRMKWKKDSKM 216
>gi|6166222|sp|P31249|HXD3_HUMAN Homeobox protein Hox-D3 (Hox-4A) Length = 416 Score = 98.6 bits (244), Expect = 2e-21 Identities = 74/210 (35%), Positives = 92/210 (43%), Gaps = 33/210 (15%) Query: 36 RPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGK 95 +P+P ASSL S C Q S + A E SC + +G S G G Sbjct: 32 QPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCM---RPGTGNSQGGGGG 88 Query: 96 QRGPGDYLHFSPEQQ---------YKPDSSSGQGKALHDEGADRKYTSP------VYPWM 140 + PG P Q P + G A +G +S ++PWM Sbjct: 89 SQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWM 148 Query: 141 Q-------RMNSCAGAVY--------GSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRR 185 + + NSCA A G +ELEKEFHFNRYL R RR Sbjct: 149 KESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRR 208 Query: 186 IEIANALCLTERQIKIWFQNRRMKWKKENK 215 +E+AN L LTERQIKIWFQNRRMK+KK+ K Sbjct: 209 VEMANLLNLTERQIKIWFQNRRMKYKKDQK 238
>gi|13124745|sp|P31273|HXC8_HUMAN Homeobox protein Hox-C8 (Hox-3A) Length = 242 Score = 95.9 bits (237), Expect = 1e-20 Identities = 86/257 (33%), Positives = 116/257 (45%), Gaps = 57/257 (22%) Query: 1 MSSYFVNPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGAS---------SLPDKT 51 MSSYFVNP F +G+ L A YD FP S G S S P Sbjct: 1 MSSYFVNPLF-SKYKAGES-------LEPAYYDC--RFPQSVGRSHALVYGPGGSAPGFQ 50 Query: 52 YT---------------SPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQ 96 + S YQQ+ L+C+ AS FY + L S G+ ++ Sbjct: 51 HASHHVQDFFHHGTSGISNSGYQQNPCSLSCHG-----DASKFYGYEALPRQSLYGAQQE 105 Query: 97 RGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXX 156 Y P+ + +++S +G+ ++ + S ++PWM+ + Sbjct: 106 ASVVQY----PDCKSSANTNSSEGQGHLNQNSS---PSLMFPWMR--------PHAPGRR 150 Query: 157 XXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 LELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN Sbjct: 151 SGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN-- 208 Query: 217 INSTQPSGEDSEAKAGE 233 N + G E K E Sbjct: 209 -NKDKLPGARDEEKVEE 224
>gi|13124737|sp|P13378|HXD8_HUMAN Homeobox protein Hox-D8 (Hox-4E) (Hox-5.4) Length = 290 Score = 92.4 bits (228), Expect = 1e-19 Identities = 57/123 (46%), Positives = 68/123 (55%), Gaps = 12/123 (9%) Query: 113 PDSSSGQGKALHDEGADRKYTSP--VYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLEL 170 PD S G D + +SP ++PWM R + G G LEL Sbjct: 160 PDCKSSSGNIGEDPDHLNQSSSPSQMFPWM-RPQAAPGRRRGRQTYSRFQT------LEL 212 Query: 171 EKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAK 230 EKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN N + E K Sbjct: 213 EKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKEN---NKDKFPVSRQEVK 269 Query: 231 AGE 233 GE Sbjct: 270 DGE 272
>gi|20141506|sp|P17481|HXB8_HUMAN Homeobox protein Hox-B8 (Hox-2D) (Hox-2.4) Length = 243 Score = 92.0 bits (227), Expect = 1e-19 Identities = 85/232 (36%), Positives = 112/232 (48%), Gaps = 45/232 (19%) Query: 1 MSSYFVNPTF----------PGSLPSGQDSFLGQLPLYQAGYDALRPF--PAS-----YG 43 MSSYFVN F P G LG P G + F P+ +G Sbjct: 1 MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHG 60 Query: 44 ASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYL 103 SSL T+P YQQ+ +AC+ FY L S G+ D + Sbjct: 61 PSSLS----TAP--YQQNPCAVACHG-----DPGNFYGYDPLQRQSLFGAQDP----DLV 105 Query: 104 HFSPEQQYKPDSSSGQGKALHDEGADRKYT-SPVYPWMQRMNSCAGAVYGSHXXXXXXXX 162 ++ K ++SG G+ EG+++ + + ++PWM R + AG G Sbjct: 106 QYA---DCKLAAASGLGEEA--EGSEQSPSPTQLFPWM-RPQAAAGRRRGRQTYSRYQT- 158 Query: 163 XXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 LELEKEF FN YLTR+RRIE+++AL LTERQ+KIWFQNRRMKWKKEN Sbjct: 159 -----LELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 205
>gi|6016293|sp|O43365|HXA3_HUMAN Homeobox protein Hox-A3 (Hox-1E) Length = 443 Score = 84.3 bits (207), Expect = 3e-17 Identities = 52/113 (46%), Positives = 63/113 (55%), Gaps = 17/113 (15%) Query: 136 VYPWMQ--RMN------------SCAG--AVYGSHXXXXXXXXXXXXXL-ELEKEFHFNR 178 ++PWM+ R N SCAG + G L ELEKEFHFNR Sbjct: 155 IFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNR 214 Query: 179 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKA 231 YL R RR+E+AN L LTERQIKIWFQNRRMK+KK+ K SG S +++ Sbjct: 215 YLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRS 267
>gi|20141537|sp|P31274|HXC9_HUMAN Homeobox protein Hox-C9 (Hox-3B) Length = 260 Score = 84.0 bits (206), Expect = 4e-17 Identities = 51/121 (42%), Positives = 64/121 (52%), Gaps = 18/121 (14%) Query: 99 PGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQ----RMNSCAGAVYGSH 154 PG+ +P+ P++ + G +E AD ++PV W+ R C Y + Sbjct: 146 PGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQT- 204 Query: 155 XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 LELEKEF FN YLTR RR E+A L LTERQ+KIWFQNRRMK KK N Sbjct: 205 -------------LELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMN 251 Query: 215 K 215 K Sbjct: 252 K 252
>gi|123268|sp|P14651|HXB3_HUMAN Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7) Length = 431 Score = 83.6 bits (205), Expect = 5e-17 Identities = 41/62 (66%), Positives = 47/62 (75%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 227 +ELEKEFHFNRYL R RR+E+AN L L+ERQIKIWFQNRRMK+KK+ K SG S Sbjct: 201 VELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPS 260 Query: 228 EA 229 A Sbjct: 261 PA 262
>gi|123286|sp|P28356|HXD9_HUMAN Homeobox protein Hox-D9 (Hox-4C) (Hox-5.2) Length = 342 Score = 79.7 bits (195), Expect = 8e-16 Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 5/181 (2%) Query: 37 PFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASY--EYGASCFYSDKDLSGASPSGSG 94 P PA+ +++ T S + SV ++ S E+ + F +K G +G G Sbjct: 158 PAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAGGDGGNGPG 217 Query: 95 KQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSH 154 G S E D G +L +E +++++ P + N A ++ Sbjct: 218 AGIGAATGTGGSSEPSACSDHPI-PGCSLKEE--EKQHSQPQQQQLDPNNPEANWIHARS 274 Query: 155 XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 LELEKEF FN YLTR RR E+A L LTERQ+KIWFQNRRMK KK + Sbjct: 275 TRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMS 334 Query: 215 K 215 K Sbjct: 335 K 335
>gi|6166216|sp|P49639|HXA1_HUMAN Homeobox protein Hox-A1 (Hox-1F) Length = 335 Score = 79.0 bits (193), Expect = 1e-15 Identities = 40/66 (60%), Positives = 47/66 (71%), Gaps = 4/66 (6%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK----LINSTQPSG 224 ELEKEFHFN+YLTR RR+EIA +L L E Q+KIWFQNRRMK KK K I+ P G Sbjct: 243 ELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPG 302 Query: 225 EDSEAK 230 D +A+ Sbjct: 303 NDEKAE 308
>gi|6016292|sp|O43364|HXA2_HUMAN Homeobox protein Hox-A2 Length = 376 Score = 77.8 bits (190), Expect = 3e-15 Identities = 42/66 (63%), Positives = 47/66 (71%), Gaps = 5/66 (7%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWK-----KENKLINSTQP 222 LELEKEFHFN+YL R RR+EIA L LTERQ+K+WFQNRRMK K KEN+ Sbjct: 156 LELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCK 215 Query: 223 SGEDSE 228 S EDSE Sbjct: 216 SLEDSE 221
>gi|1708540|sp|P52945|IPF1_HUMAN Insulin promoter factor-1 (IPF-1) (Pancreas/duodenum homeobox-1) (PDX-1) (Islet/duodenum homeobox-1) (IDX-1) (Somatostatin transactivating factor-1) (STF-1) (Insulin upstream factor-1) (IUF-1) (Glucose-sensitive factor) (GSF) Length = 283 Score = 77.0 bits (188), Expect = 5e-15 Identities = 41/86 (47%), Positives = 50/86 (58%), Gaps = 9/86 (10%) Query: 137 YPWMQRMNS------CAGAVYGSH---XXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIE 187 +PWM+ + AG Y + LELEKEF FN+Y++R RR+E Sbjct: 119 FPWMKSTKAHAWKGQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVE 178 Query: 188 IANALCLTERQIKIWFQNRRMKWKKE 213 +A L LTER IKIWFQNRRMKWKKE Sbjct: 179 LAVMLNLTERHIKIWFQNRRMKWKKE 204
>gi|6166219|sp|P31269|HXA9_HUMAN Homeobox protein Hox-A9 (Hox-1G) Length = 272 Score = 76.6 bits (187), Expect = 6e-15 Identities = 49/118 (41%), Positives = 58/118 (49%), Gaps = 10/118 (8%) Query: 101 DYLHFSPEQQYKPDSSSG---QGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXX 157 DY SP + S G + A ++ G D+ P N A ++ Sbjct: 156 DYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDP-------NNPAANWLHARSTRK 208 Query: 158 XXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELEKEF FN YLTR RR E+A L LTERQ+KIWFQNRRMK KK NK Sbjct: 209 KRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINK 266
>gi|123270|sp|P14652|HXB2_HUMAN Homeobox protein Hox-B2 (Hox-2H) (Hox-2.8) (K8) Length = 356 Score = 76.6 bits (187), Expect = 6e-15 Identities = 37/58 (63%), Positives = 45/58 (77%), Gaps = 2/58 (3%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGE 225 LELEKEFHFN+YL R RR+EIA L LTERQ+K+WFQNRRMK K++ + + P GE Sbjct: 156 LELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQ--HREPPDGE 211
>gi|17378648|sp|Q9GZZ0|HXD1_HUMAN Homeobox protein Hox-D1 Length = 328 Score = 76.3 bits (186), Expect = 8e-15 Identities = 35/47 (74%), Positives = 39/47 (82%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEKEFHFN+YLTR RRIEIAN L L + Q+KIWFQNRRMK KK + Sbjct: 243 ELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKRER 289
>gi|1345720|sp|P47902|CDX1_HUMAN Homeobox protein CDX-1 (Caudal-type homeobox protein 1) Length = 265 Score = 75.5 bits (184), Expect = 1e-14 Identities = 64/190 (33%), Positives = 80/190 (42%), Gaps = 15/190 (7%) Query: 39 PASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRG 98 PA+YG + P P F S+ V +GA D + A G Sbjct: 27 PANYGPPAPPPAPPQYPDFSSYSH-VEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAA 85 Query: 99 PGDYLHFSPEQQYKP---DSSSGQGKALHDEGADRKYTSP------VYPWMQRMNSCAGA 149 L F P + P G G G +SP Y WM+R + AG Sbjct: 86 SPASLAFGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPTPYEWMRR-SVAAGG 144 Query: 150 VYGSHXXXXXXXXXXXXX----LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQN 205 GS LELEKEFH++RY+T RR+ E+A L LTERQ+KIWFQN Sbjct: 145 GGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQN 204 Query: 206 RRMKWKKENK 215 RR K +K NK Sbjct: 205 RRAKERKVNK 214
>gi|20141612|sp|Q9NYD6|HXC10_HUMAN Homeobox protein Hox-C10 Length = 342 Score = 73.6 bits (179), Expect = 5e-14 Identities = 34/48 (70%), Positives = 40/48 (83%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELEKEF FN YLTR RR+EI+ + LT+RQ+KIWFQNRRMK KK N+ Sbjct: 281 LELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR 328
>gi|13124743|sp|P31260|HXA10_HUMAN Homeobox protein Hox-A10 (Hox-1H) (Hox-1.8) (PL) Length = 393 Score = 73.6 bits (179), Expect = 5e-14 Identities = 34/48 (70%), Positives = 41/48 (85%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNRRMK KK N+ Sbjct: 332 LELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNR 379
>gi|20141507|sp|P17482|HXB9_HUMAN Homeobox protein Hox-B9 (Hox-2E) (Hox-2.5) Length = 250 Score = 73.2 bits (178), Expect = 7e-14 Identities = 36/48 (75%), Positives = 39/48 (81%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELEKEF FN YLTR RR E+A L L+ERQ+KIWFQNRRMK KK NK Sbjct: 198 LELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245
>gi|123271|sp|P14653|HXB1_HUMAN Homeobox protein Hox-B1 (Hox-2I) Length = 301 Score = 72.0 bits (175), Expect = 2e-13 Identities = 33/47 (70%), Positives = 38/47 (80%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEKEFHFN+YL+R RR+EIA L L E Q+KIWFQNRRMK KK + Sbjct: 217 ELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKRER 263
>gi|123289|sp|P28358|HXD10_HUMAN Homeobox protein Hox-D10 (Hox-4D) (Hox-4E) Length = 340 Score = 71.6 bits (174), Expect = 2e-13 Identities = 33/48 (68%), Positives = 41/48 (85%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELEKEF FN YLTR RR+EI+ ++ LT+RQ+KIWFQNRRMK KK ++ Sbjct: 279 LELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSR 326
>gi|45644931|sp|P50219|HLXB9_HUMAN Homeobox protein HB9 Length = 403 Score = 71.6 bits (174), Expect = 2e-13 Identities = 32/65 (49%), Positives = 47/65 (72%), Gaps = 3/65 (4%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 227 LELE +F N+YL+R +R E+A +L LTE Q+KIWFQNRRMKWK+ K + + + +++ Sbjct: 256 LELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKK---AKEQAAQEA 312 Query: 228 EAKAG 232 E + G Sbjct: 313 EKQKG 317
>gi|20141282|sp|Q99626|CDX2_HUMAN Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3) Length = 313 Score = 70.9 bits (172), Expect = 4e-13 Identities = 62/198 (31%), Positives = 84/198 (42%), Gaps = 36/198 (18%) Query: 38 FPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQR 97 +PA+YGA D +P + A N ++ L+G SP+ + Sbjct: 65 WPAAYGAPLREDWNGYAP-----GGAAAAANAVAH-----------GLNGGSPAAAMGYS 108 Query: 98 GPGDYL------HFSPEQQYKPDSSSGQGKALHDEGADRKYTSP---VYPWMQRMNSC-- 146 P DY H P +SG + L+ T+ + P QR N C Sbjct: 109 SPADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEW 168 Query: 147 ----AGAVYGSHXXXXXXXX-----XXXXXLELEKEFHFNRYLTRRRRIEIANALCLTER 197 A GS LELEKEFH++RY+T RR+ E+A L L+ER Sbjct: 169 MRKPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSER 228 Query: 198 QIKIWFQNRRMKWKKENK 215 Q+KIWFQNRR K +K NK Sbjct: 229 QVKIWFQNRRAKERKINK 246
>gi|12644203|sp|P31277|HXD11_HUMAN Homeobox protein Hox-D11 (Hox-4F) Length = 338 Score = 68.6 bits (166), Expect = 2e-12 Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Query: 114 DSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKE 173 + S G G+ E K +S V P R C Y ELE+E Sbjct: 239 EGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIR--------------ELERE 284 Query: 174 FHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 F FN Y+ + +R++++ L LT+RQ+KIWFQNRRMK KK N+ Sbjct: 285 FFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNR 326
>gi|20138327|sp|Q9BZM3|GSH2_HUMAN Homeobox protein GSH-2 Length = 304 Score = 68.2 bits (165), Expect = 2e-12 Identities = 33/48 (68%), Positives = 39/48 (81%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELE+EF N YL+R RRIEIA L L+E+Q+KIWFQNRR+K KKE K Sbjct: 215 LELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 262
>gi|27923786|sp|Q9H4S2|GSHI_HUMAN Homeobox protein GSH-1 Length = 264 Score = 67.8 bits (164), Expect = 3e-12 Identities = 33/48 (68%), Positives = 39/48 (81%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LELE+EF N YL+R RRIEIA L L+E+Q+KIWFQNRR+K KKE K Sbjct: 160 LELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
>gi|1709079|sp|P50222|MEOX2_HUMAN Homeobox protein MOX-2 (Mesenchyme homeobox 2) (Growth arrest-specific homeobox) Length = 303 Score = 67.4 bits (163), Expect = 4e-12 Identities = 45/132 (34%), Positives = 59/132 (44%), Gaps = 17/132 (12%) Query: 81 SDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWM 140 + L ++P+G+ PGDY + S G+ K+ + + Y S V Sbjct: 129 NSSSLGSSTPTGAAC--APGDYGRQALSPAEAEKRSGGKRKSDSSDSQEGNYKSEV---- 182 Query: 141 QRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIK 200 S ELE EF + YLTR RR EIA L LTERQ+K Sbjct: 183 -----------NSKPRKERTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVK 231 Query: 201 IWFQNRRMKWKK 212 +WFQNRRMKWK+ Sbjct: 232 VWFQNRRMKWKR 243
>gi|1709078|sp|P50221|MEOX1_HUMAN Homeobox protein MOX-1 (Mesenchyme homeobox 1) Length = 254 Score = 67.4 bits (163), Expect = 4e-12 Identities = 35/60 (58%), Positives = 42/60 (70%), Gaps = 1/60 (1%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 ELE EF + YLTR RR EIA L L+ERQ+K+WFQNRRMKWK+ K P+G+D E Sbjct: 185 ELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV-KGGQPISPNGQDPE 243
>gi|12644308|sp|P52951|GBX2_HUMAN Homeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2) Length = 348 Score = 66.6 bits (161), Expect = 7e-12 Identities = 34/60 (56%), Positives = 43/60 (71%), Gaps = 1/60 (1%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 227 LELEKEFH +YL+ R +IA+AL L+E Q+KIWFQNRR KWK+ K N+ +GE S Sbjct: 260 LELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRV-KAGNANSKTGEPS 318
>gi|12230077|sp|Q14549|GBX1_HUMAN Homeobox protein GBX-1 (Gastrulation and brain-specific homeobox protein 1) Length = 139 Score = 65.1 bits (157), Expect = 2e-11 Identities = 34/58 (58%), Positives = 42/58 (72%), Gaps = 1/58 (1%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGE 225 LELEKEFH +YL+ R +IA+AL L+E Q+KIWFQNRR KWK+ K N + SGE Sbjct: 50 LELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKR-IKAGNVSSRSGE 106
>gi|3023467|sp|O14627|CDX4_HUMAN Homeobox protein CDX-4 (Caudal-type homeobox protein 4) Length = 284 Score = 64.7 bits (156), Expect = 3e-11 Identities = 55/155 (35%), Positives = 69/155 (44%), Gaps = 29/155 (18%) Query: 80 YSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPW 139 + D S P G G G L P + +G KA R SP Y W Sbjct: 108 FCSTDYSNLGPVGGGTS---GSSLPGQAGGSLVP-TDAGAAKA---SSPSRSRHSP-YAW 159 Query: 140 MQRMNSCAG---------AVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIAN 190 M++ G VY H LELEKEFH NRY+T +R+ E+A Sbjct: 160 MRKTVQVTGKTRTKEKYRVVYTDHQR-----------LELEKEFHCNRYITIQRKSELAV 208 Query: 191 ALCLTERQIKIWFQNRRMKWKKE-NKLINSTQPSG 224 L L+ERQ+KIWFQNRR K +K K I+ + SG Sbjct: 209 NLGLSERQVKIWFQNRRAKERKMIKKKISQFENSG 243
>gi|3287858|sp|O43248|HXC11_HUMAN Homeobox protein Hox-C11 Length = 304 Score = 62.4 bits (150), Expect = 1e-10 Identities = 55/187 (29%), Positives = 80/187 (42%), Gaps = 32/187 (17%) Query: 41 SYGASSLPDKTYTSPC-FYQQSNSVLACNRASYEYGASCFYSDKDLSGASP-SGSGKQRG 98 SYG P + +P FY N +A + + + D P SG G+ +G Sbjct: 120 SYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKG 179 Query: 99 -----PGDYL--------HFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNS 145 P L E++ SSSG ++ E A K +P P R Sbjct: 180 EPEAPPASGLASRAEAGAEAEAEEENTNPSSSGSAHSVAKEPA--KGAAPNAP-RTRKKR 236 Query: 146 CAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQN 205 C + + ELE+EF FN Y+ + +R++++ L LT+RQ+KIWFQN Sbjct: 237 CPYSKFQIR--------------ELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQN 282 Query: 206 RRMKWKK 212 RRMK KK Sbjct: 283 RRMKEKK 289
>gi|13124744|sp|P31270|HXA11_HUMAN Homeobox protein Hox-A11 (Hox-1I) Length = 313 Score = 61.6 bits (148), Expect = 2e-10 Identities = 26/47 (55%), Positives = 38/47 (80%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE+EF F+ Y+ + +R++++ L LT+RQ+KIWFQNRRMK KK N+ Sbjct: 255 ELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINR 301
>gi|6016211|sp|P78426|NK61_HUMAN Homeobox protein Nkx-6.1 Length = 367 Score = 59.7 bits (143), Expect = 8e-10 Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 25/112 (22%) Query: 119 QGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNR 178 QG L D+ RK+T P + Q LEK F + Sbjct: 225 QGSILLDKDGKRKHTRPTFSGQQ-------------------------IFALEKTFEQTK 259 Query: 179 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAK 230 YL R +A +L +TE Q+K+WFQNRR KW+K++ +T +DSE + Sbjct: 260 YLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETE 311
>gi|399982|sp|P31314|TLX1_HUMAN T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (TCL-3 proto-oncogene) Length = 330 Score = 56.2 bits (134), Expect = 9e-09 Identities = 23/45 (51%), Positives = 31/45 (68%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELEK FH +YL R +A AL +T+ Q+K WFQNRR KW+++ Sbjct: 215 ELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQ 259
>gi|20141538|sp|P31275|HXC12_HUMAN Homeobox protein Hox-C12 (Hox-3F) Length = 282 Score = 56.2 bits (134), Expect = 9e-09 Identities = 25/44 (56%), Positives = 36/44 (81%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELE EF N ++TR+RR E+++ L L+++Q+KIWFQNRRMK K+ Sbjct: 228 ELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKR 271
>gi|12644227|sp|P35452|HXD12_HUMAN Homeobox protein Hox-D12 (Hox-4H) Length = 275 Score = 55.8 bits (133), Expect = 1e-08 Identities = 24/44 (54%), Positives = 35/44 (79%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELE EF N ++ R++R E++N L L+++Q+KIWFQNRRMK K+ Sbjct: 221 ELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKR 264
>gi|2833256|sp|Q14774|HLX1_HUMAN Homeobox protein HLX1 (Homeobox protein HB24) Length = 488 Score = 55.8 bits (133), Expect = 1e-08 Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 5/64 (7%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 LEK F +Y+T+ R ++A L LT+ Q+K+WFQNRRMKW+ + + +D + Sbjct: 291 LEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKE-----AQAQKDKDK 345 Query: 230 KAGE 233 +AGE Sbjct: 346 EAGE 349
>gi|12231013|sp|Q03828|EVX2_HUMAN Homeobox even-skipped homolog protein 2 (EVX-2) Length = 476 Score = 55.8 bits (133), Expect = 1e-08 Identities = 27/54 (50%), Positives = 37/54 (68%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPS 223 LEKEF+ Y++R RR E+A AL L E IK+WFQNRRMK K++ ++ P+ Sbjct: 203 LEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPHPA 256
>gi|1352398|sp|P49640|EVX1_HUMAN Homeobox even-skipped homolog protein 1 (EVX-1) Length = 407 Score = 55.5 bits (132), Expect = 2e-08 Identities = 27/54 (50%), Positives = 36/54 (66%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPS 223 LEKEF+ Y++R RR E+A AL L E IK+WFQNRRMK K++ + P+ Sbjct: 198 LEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPA 251
>gi|13431329|sp|Q9UMQ3|BARX2_HUMAN Homeobox protein BarH-like 2 Length = 254 Score = 55.1 bits (131), Expect = 2e-08 Identities = 23/43 (53%), Positives = 33/43 (76%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 LEK+F +YL+ R+++A +L LT+ Q+K W+QNRRMKWKK Sbjct: 123 LEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 165
>gi|23831508|sp|O43711|TLX3_HUMAN T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2) Length = 291 Score = 55.1 bits (131), Expect = 2e-08 Identities = 22/45 (48%), Positives = 31/45 (68%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELEK FH +YL R +A +L +T+ Q+K WFQNRR KW+++ Sbjct: 180 ELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQ 224
>gi|50403792|sp|Q92826|HXB13_HUMAN Homeobox protein Hox-B13 Length = 284 Score = 54.3 bits (129), Expect = 3e-08 Identities = 28/55 (50%), Positives = 40/55 (72%), Gaps = 1/55 (1%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKLINSTQP 222 ELE+E+ N+++T+ +R +I+ A L+ERQI IWFQNRR+K KK K+ NS P Sbjct: 230 ELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLAKVKNSATP 284
>gi|547658|sp|Q03014|HHEX_HUMAN Homeobox protein PRH (Hematopoietically expressed homeobox) (Homeobox protein HEX) Length = 270 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 3/57 (5%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKW---KKENKLINSTQ 221 +ELEK+F +YL+ R +A L L+ERQ+K WFQNRR KW K+EN N + Sbjct: 150 IELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKE 206
>gi|14194481|sp|Q9HBU1|BARX1_HUMAN Homeobox protein BarH-like 1 Length = 225 Score = 54.3 bits (129), Expect = 3e-08 Identities = 27/59 (45%), Positives = 38/59 (64%), Gaps = 4/59 (6%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK----ENKLINSTQPSG 224 LEK F +YL+ RI++A +L L++ Q+K W+QNRRMKWKK L + T+P G Sbjct: 128 LEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKG 186
>gi|21903415|sp|P19622|HME2_HUMAN Homeobox protein engrailed-2 (Hu-En-2) Length = 333 Score = 53.9 bits (128), Expect = 4e-08 Identities = 26/43 (60%), Positives = 30/43 (69%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L+ EF NRYLT +RR +A L L E QIKIWFQN+R K KK Sbjct: 259 LKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 301
>gi|19862512|sp|Q04743|EMX2_HUMAN Homeobox protein EMX2 (Empty spiracles homolog 2) (Empty spiracles-like protein 2) Length = 252 Score = 53.5 bits (127), Expect = 6e-08 Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 5/63 (7%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 227 L LE F N Y+ R ++A++L LTE Q+K+WFQNRR K+K++ + G DS Sbjct: 167 LRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ-----KLEEEGSDS 221 Query: 228 EAK 230 + K Sbjct: 222 QQK 224
>gi|14917010|sp|Q05925|HME1_HUMAN Homeobox protein engrailed-1 (Hu-En-1) Length = 392 Score = 53.5 bits (127), Expect = 6e-08 Identities = 26/49 (53%), Positives = 32/49 (65%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLIN 218 L+ EF NRY+T +RR +A L L E QIKIWFQN+R K KK + N Sbjct: 318 LKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGIKN 366
>gi|20532295|sp|Q9UIW0|VAX2_HUMAN Ventral anterior homeobox 2 Length = 290 Score = 52.4 bits (124), Expect = 1e-07 Identities = 28/62 (45%), Positives = 36/62 (58%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 LE EF +Y+ R R E+A L L+E Q+K+WFQNRR K KK+ + S SEA Sbjct: 117 LEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEA 176 Query: 230 KA 231 A Sbjct: 177 FA 178
>gi|29336920|sp|Q9BZE3|BARH1_HUMAN BarH-like 1 homeobox protein (FKSG31 protein) Length = 327 Score = 52.4 bits (124), Expect = 1e-07 Identities = 21/45 (46%), Positives = 34/45 (75%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 +LE+ F +YL+ + R+E+A +L LT+ Q+K W+QNRR KWK++ Sbjct: 192 QLERSFERQKYLSVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQ 236
>gi|6016210|sp|P78367|NK32_HUMAN Homeobox protein Nkx-3.2 (Bagpipe homeobox protein homolog 1) Length = 333 Score = 52.4 bits (124), Expect = 1e-07 Identities = 24/44 (54%), Positives = 32/44 (72%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELE+ F+ RYL+ R ++A +L LTE Q+KIWFQNRR K K+ Sbjct: 220 ELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR 263
>gi|57015304|sp|Q04741|EMX1_HUMAN Homeobox protein EMX1 (Empty spiracles homolog 1) (Empty spiracles-like protein 1) Length = 257 Score = 52.4 bits (124), Expect = 1e-07 Identities = 25/63 (39%), Positives = 38/63 (60%), Gaps = 5/63 (7%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDS 227 L LE+ F N Y+ R ++A +L L+E Q+K+WFQNRR K+K++ + G +S Sbjct: 172 LRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQ-----KLEEEGPES 226 Query: 228 EAK 230 E K Sbjct: 227 EQK 229
>gi|20532396|sp|O43763|TLX2_HUMAN T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein) Length = 284 Score = 52.4 bits (124), Expect = 1e-07 Identities = 22/46 (47%), Positives = 31/46 (67%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 LELE+ F +YL R +A AL +T+ Q+K WFQNRR KW+++ Sbjct: 170 LELERRFLRQKYLASAERAALAKALRMTDAQVKTWFQNRRTKWRRQ 215
>gi|47117915|sp|Q9NY43|BARH2_HUMAN BarH-like 2 homeobox protein Length = 387 Score = 52.4 bits (124), Expect = 1e-07 Identities = 21/45 (46%), Positives = 34/45 (75%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 +LE+ F +YL+ + R+++A AL LT+ Q+K W+QNRR KWK++ Sbjct: 246 QLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQ 290
>gi|17377578|sp|Q99801|NKX31_HUMAN Homeobox protein Nkx-3.1 Length = 234 Score = 51.2 bits (121), Expect = 3e-07 Identities = 23/46 (50%), Positives = 32/46 (69%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 +ELE++F +YL+ R +A L LTE Q+KIWFQNRR K K++ Sbjct: 137 IELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRK 182
>gi|27923733|sp|Q96QS3|ARX_HUMAN Homeobox protein ARX (Aristaless-related homeobox) Length = 562 Score = 51.2 bits (121), Expect = 3e-07 Identities = 25/56 (44%), Positives = 32/56 (57%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG 224 ELE+ F Y R E+A L LTE ++++WFQNRR KW+K K T P G Sbjct: 342 ELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPG 397
>gi|1708211|sp|P52952|NK25_HUMAN Homeobox protein Nkx-2.5 (Homeobox protein NK-2 homolog E) (Cardiac-specific homeobox) (Homeobox protein CSX) Length = 324 Score = 50.4 bits (119), Expect = 5e-07 Identities = 23/47 (48%), Positives = 32/47 (68%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE+ F RYL+ R ++A+ L LT Q+KIWFQNRR K K++ + Sbjct: 152 ELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQ 198
>gi|2828197|sp|P31271|HXA13_HUMAN Homeobox protein Hox-A13 (Hox-1J) Length = 388 Score = 50.4 bits (119), Expect = 5e-07 Identities = 25/49 (51%), Positives = 36/49 (73%), Gaps = 1/49 (2%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKL 216 ELE+E+ N+++T+ +R I+ L+ERQ+ IWFQNRR+K KK NKL Sbjct: 336 ELEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKL 384
>gi|20141539|sp|P31276|HXC13_HUMAN Homeobox protein Hox-C13 (Hox-3G) Length = 330 Score = 50.1 bits (118), Expect = 6e-07 Identities = 22/44 (50%), Positives = 33/44 (75%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELEKE+ ++++T+ +R I+ L+ERQ+ IWFQNRR+K KK Sbjct: 274 ELEKEYAASKFITKEKRRRISATTNLSERQVTIWFQNRRVKEKK 317
>gi|23503066|sp|P28360|MSX1_HUMAN Homeobox protein MSX-1 (Hox-7) Length = 297 Score = 50.1 bits (118), Expect = 6e-07 Identities = 23/45 (51%), Positives = 32/45 (71%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L LE++F +YL+ R E +++L LTE Q+KIWFQNRR K K+ Sbjct: 179 LALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKR 223
>gi|27923815|sp|Q8TAU0|NKX23_HUMAN Homeobox protein Nkx-2.3 (Homeobox protein NKX-2.3) (Homeobox protein NK-2 homolog C) Length = 364 Score = 50.1 bits (118), Expect = 6e-07 Identities = 23/47 (48%), Positives = 32/47 (68%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE+ F RYL+ R +A++L LT Q+KIWFQNRR K K++ + Sbjct: 162 ELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQ 208
>gi|38605720|sp|P56177|DLX1_HUMAN Homeobox protein DLX-1 Length = 255 Score = 50.1 bits (118), Expect = 6e-07 Identities = 35/109 (32%), Positives = 49/109 (44%), Gaps = 6/109 (5%) Query: 104 HFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXX 163 + S Q Y +S Q + L D GAD + ++ V R N G Sbjct: 83 YISSVQSYPGSASLAQSR-LEDPGADSEKSTVVEGGEVRFNG-----KGKKIRKPRTIYC 136 Query: 164 XXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L + F +YL R E+A +L LT+ Q+KIWFQN+R K+KK Sbjct: 137 SLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 185
>gi|2851475|sp|P35453|HXD13_HUMAN Homeobox protein Hox-D13 (Hox-4I) Length = 335 Score = 49.3 bits (116), Expect = 1e-06 Identities = 22/44 (50%), Positives = 32/44 (72%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELE E+ N+++ + +R I+ A L+ERQ+ IWFQNRR+K KK Sbjct: 282 ELENEYAINKFINKDKRRRISAATNLSERQVTIWFQNRRVKDKK 325
>gi|13959687|sp|P35548|MSX2_HUMAN Homeobox protein MSX-2 (Hox-8) Length = 267 Score = 49.3 bits (116), Expect = 1e-06 Identities = 23/45 (51%), Positives = 32/45 (71%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L LE++F +YL+ R E +++L LTE Q+KIWFQNRR K K+ Sbjct: 155 LALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKR 199
>gi|2506529|sp|Q07687|DLX2_HUMAN Homeobox protein DLX-2 Length = 328 Score = 48.5 bits (114), Expect = 2e-06 Identities = 22/43 (51%), Positives = 30/43 (69%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L++ F +YL R E+A +L LT+ Q+KIWFQNRR K+KK Sbjct: 167 LQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNRRSKFKK 209
>gi|6016208|sp|O15522|NK28_HUMAN Homeobox protein Nkx-2.8 (Homeobox protein NK-2 homolog H) Length = 239 Score = 48.5 bits (114), Expect = 2e-06 Identities = 23/45 (51%), Positives = 30/45 (66%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 LELE+ F RYL+ R ++A+ L LT Q+KIWFQN R K K+ Sbjct: 97 LELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKR 141
>gi|1174819|sp|P43699|TITF1_HUMAN Thyroid transcription factor 1 (Thyroid nuclear factor 1) (TTF-1) (Homeobox protein Nkx-2.1) (Homeobox protein NK-2 homolog A) Length = 371 Score = 48.1 bits (113), Expect = 2e-06 Identities = 25/64 (39%), Positives = 36/64 (56%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 ELE+ F +YL+ R +A+ + LT Q+KIWFQN R K K++ K + Q +DS Sbjct: 175 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSG 234 Query: 229 AKAG 232 G Sbjct: 235 GGGG 238
>gi|6174907|sp|Q99697|PITX2_HUMAN Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1 responsive protein ARP1) Length = 317 Score = 47.4 bits (111), Expect = 4e-06 Identities = 22/47 (46%), Positives = 29/47 (61%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE F NRY R EIA LTE ++++WF+NRR KW+K + Sbjct: 99 ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 145
>gi|6093723|sp|O75364|PITX3_HUMAN Pituitary homeobox 3 (Homeobox protein PITX3) Length = 302 Score = 47.4 bits (111), Expect = 4e-06 Identities = 22/47 (46%), Positives = 29/47 (61%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE F NRY R EIA LTE ++++WF+NRR KW+K + Sbjct: 76 ELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 122
>gi|3913487|sp|O60479|DLX3_HUMAN Homeobox protein DLX-3 Length = 287 Score = 47.0 bits (110), Expect = 5e-06 Identities = 22/43 (51%), Positives = 29/43 (67%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L++ F +YL R E+A L LT+ Q+KIWFQNRR K+KK Sbjct: 144 LQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKK 186
>gi|3024482|sp|P78337|PITX1_HUMAN Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot) Length = 314 Score = 47.0 bits (110), Expect = 5e-06 Identities = 22/47 (46%), Positives = 29/47 (61%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE F NRY R EIA LTE ++++WF+NRR KW+K + Sbjct: 103 ELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149
>gi|1730095|sp|P52954|LBX1_HUMAN Transcription factor LBX1 Length = 280 Score = 47.0 bits (110), Expect = 5e-06 Identities = 23/45 (51%), Positives = 29/45 (64%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELEK F + +YL+ R +IA L LT Q+ WFQNRR K K+E Sbjct: 138 ELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRE 182
>gi|27923817|sp|Q9H2Z4|NK24_HUMAN Homeobox protein Nkx-2.4 (Homeobox protein NKX2.4) (Homeobox protein NK-2 homolog D) Length = 353 Score = 46.2 bits (108), Expect = 9e-06 Identities = 21/47 (44%), Positives = 30/47 (63%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE+ F +YL+ R +A+ + LT Q+KIWFQN R K K++ K Sbjct: 203 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAK 249
>gi|6016205|sp|O95096|NKX22_HUMAN Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) Length = 273 Score = 45.8 bits (107), Expect = 1e-05 Identities = 21/44 (47%), Positives = 28/44 (63%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 ELE+ F RYL+ R +A+ + LT Q+KIWFQN R K K+ Sbjct: 142 ELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKR 185
>gi|12644329|sp|P56178|DLX5_HUMAN Homeobox protein DLX-5 Length = 289 Score = 45.8 bits (107), Expect = 1e-05 Identities = 21/43 (48%), Positives = 29/43 (67%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L++ F +YL R E+A +L LT+ Q+KIWFQN+R K KK Sbjct: 152 LQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK 194
>gi|6174889|sp|P26367|PAX6_HUMAN Paired box protein Pax-6 (Oculorhombin) (Aniridia, type II protein) Length = 422 Score = 45.8 bits (107), Expect = 1e-05 Identities = 22/49 (44%), Positives = 29/49 (59%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLIN 218 LEKEF Y R +A + L E +I++WF NRR KW++E KL N Sbjct: 225 LEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRN 273
>gi|17380297|sp|Q9Y2V3|RX_HUMAN Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein) Length = 346 Score = 45.8 bits (107), Expect = 1e-05 Identities = 20/48 (41%), Positives = 31/48 (64%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 ELE+ F + Y R E+A + L E ++++WFQNRR KW+++ KL Sbjct: 150 ELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKL 197
>gi|3914276|sp|O43316|PAX4_HUMAN Paired box protein Pax-4 Length = 350 Score = 45.8 bits (107), Expect = 1e-05 Identities = 20/47 (42%), Positives = 29/47 (61%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 LEKEF +Y R ++A A L E +++WF NRR KW+++ KL Sbjct: 185 LEKEFQRGQYPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKL 231
>gi|12644330|sp|P56179|DLX6_HUMAN Homeobox protein DLX-6 Length = 175 Score = 45.4 bits (106), Expect = 2e-05 Identities = 21/43 (48%), Positives = 28/43 (65%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L F +YL R E+A +L LT+ Q+KIWFQN+R K+KK Sbjct: 64 LNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 106
>gi|3915680|sp|Q92988|DLX4_HUMAN Homeobox protein DLX-4 (DLX-7) (DLX-8) Length = 347 Score = 45.4 bits (106), Expect = 2e-05 Identities = 20/43 (46%), Positives = 28/43 (65%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 L + F +YL R ++A L LT+ Q+KIWFQN+R K+KK Sbjct: 240 LNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKK 282
>gi|8134640|sp|O14813|PHX2A_HUMAN Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein) Length = 284 Score = 44.3 bits (103), Expect = 4e-05 Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 1/65 (1%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 ELE+ F Y R E+A + LTE ++++WFQNRR K++K+ + ++ +G + Sbjct: 104 ELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAASAKGAAGA-AG 162 Query: 229 AKAGE 233 AK GE Sbjct: 163 AKKGE 167
>gi|13626112|sp|Q9H161|ALX4_HUMAN Homeobox protein aristaless-like 4 Length = 411 Score = 44.3 bits (103), Expect = 4e-05 Identities = 20/47 (42%), Positives = 28/47 (59%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEK F Y R ++A LTE ++++WFQNRR KW+K + Sbjct: 228 ELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRER 274
>gi|37537987|sp|Q9BQY4|PEP2_HUMAN Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1) Length = 288 Score = 43.9 bits (102), Expect = 5e-05 Identities = 28/131 (21%), Positives = 55/131 (41%), Gaps = 2/131 (1%) Query: 87 GASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSC 146 G G G+++ G P ++ D G + E +D+ P + + + Sbjct: 68 GEEKDGGGEEKDGGGA--GVPGHLWEGDLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAV 125 Query: 147 AGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNR 206 G G+ ELE+ F ++ + R +A ++ +TE ++IWF+NR Sbjct: 126 GGLEPGNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENR 185 Query: 207 RMKWKKENKLI 217 R KW++ + + Sbjct: 186 RAKWRRHQRAL 196
>gi|48428084|sp|Q8N693|ESX1L_HUMAN Extraembryonic, spermatogenesis, homeobox 1-like protein Length = 406 Score = 43.9 bits (102), Expect = 5e-05 Identities = 20/49 (40%), Positives = 31/49 (63%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLI 217 ELE F ++Y R +A L LTE ++++WFQNRR KWK+ +++ Sbjct: 153 ELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVL 201
>gi|13626107|sp|O95076|ALX3_HUMAN Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3) Length = 343 Score = 43.9 bits (102), Expect = 5e-05 Identities = 20/47 (42%), Positives = 28/47 (59%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEK F Y R ++A LTE ++++WFQNRR KW+K + Sbjct: 167 ELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRER 213
>gi|12644347|sp|P78413|IRX4_HUMAN Iroquois-class homeodomain protein IRX-4 (Iroquois homeobox protein 4) (Homeodomain protein IRXA3) Length = 519 Score = 43.5 bits (101), Expect = 6e-05 Identities = 44/178 (24%), Positives = 60/178 (33%), Gaps = 43/178 (24%) Query: 68 NRASYEYGASCFYSDKDLSGASPSGS---GKQRGPGDYLHFSPEQ-QYKPDSSSGQGKAL 123 N +Y AS FYS SGS G Y + P QY D Sbjct: 85 NYVTYGSEASAFYSLNSFDSKDGSGSAHGGLAPAAAAYYPYEPALGQYPYDRYGTMDSGT 144 Query: 124 HDEGADRKYTSPVYPWMQRMNSCAGAVYGSHXXXXXXXXXXXXXLELEKEFHFNRYLTRR 183 + A R+ TS + W+Q E N Y T+ Sbjct: 145 RRKNATRETTSTLKAWLQ-------------------------------EHRKNPYPTKG 173 Query: 184 RRIEIANALCLTERQIKIWFQNRRMKWKKENKL--------INSTQPSGEDSEAKAGE 233 +I +A +T Q+ WF N R + KKENK+ + +P E E + GE Sbjct: 174 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGE 231
>gi|8247951|sp|P23759|PAX7_HUMAN Paired box protein Pax-7 (HUP1) Length = 520 Score = 43.5 bits (101), Expect = 6e-05 Identities = 19/45 (42%), Positives = 27/45 (60%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELEK F Y R E+A LTE ++++WF NRR +W+K+ Sbjct: 231 ELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275
>gi|3023579|sp|Q15699|CRT1_HUMAN Cartilage homeoprotein 1 (CART-1) Length = 326 Score = 42.7 bits (99), Expect = 1e-04 Identities = 20/47 (42%), Positives = 28/47 (59%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEK F Y R ++A LTE ++++WFQNRR KW+K + Sbjct: 146 ELEKVFQKTHYPDVYVREQLALRTELTEARVQVWFQNRRAKWRKRER 192
>gi|1172022|sp|P23760|PAX3_HUMAN Paired box protein Pax-3 (HUP2) Length = 479 Score = 42.4 bits (98), Expect = 1e-04 Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELE+ F Y R E+A LTE ++++WF NRR +W+K+ Sbjct: 233 ELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ 277
>gi|17374365|sp|P58304|CHX10_HUMAN Homeobox protein CHX10 (Ceh-10 homeodomain containing homolog) Length = 361 Score = 41.2 bits (95), Expect = 3e-04 Identities = 21/47 (44%), Positives = 27/47 (57%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEK F+ Y R +A L E +I++WFQNRR KW+K K Sbjct: 162 ELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREK 208
>gi|8134644|sp|Q99453|PHX2B_HUMAN Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox) Length = 314 Score = 41.2 bits (95), Expect = 3e-04 Identities = 19/47 (40%), Positives = 30/47 (63%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE+ F Y R E+A + LTE ++++WFQNRR K++K+ + Sbjct: 112 ELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQER 158
>gi|18202099|sp|O60902|SHOX2_HUMAN Short stature homeobox protein 2 (Paired-related homeobox protein SHOT) (Homeobox protein Og12X) Length = 331 Score = 40.4 bits (93), Expect = 5e-04 Identities = 21/63 (33%), Positives = 35/63 (55%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 ELE+ F Y R E++ L L+E ++++WFQNRR K +K+ ++ G S+ Sbjct: 154 ELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQ 213 Query: 229 AKA 231 +A Sbjct: 214 FEA 216
>gi|25009572|sp|Q9NZR4|VSX1_HUMAN Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX) Length = 365 Score = 40.0 bits (92), Expect = 7e-04 Identities = 21/47 (44%), Positives = 26/47 (55%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELEK F Y R +A L E +I++WFQNRR KW+K K Sbjct: 178 ELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224
>gi|47117872|sp|P78412|IRX6_HUMAN Iroquois-class homeodomain protein IRX-6 (Iroquois homeobox protein 6) (Homeodomain protein IRXB3) Length = 445 Score = 39.7 bits (91), Expect = 9e-04 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%) Query: 173 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ-PSGEDSEAKA 231 E N Y T+ +I +A +T Q+ WF N R + KKENK+ + + GE+ +A+ Sbjct: 167 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEG 226 Query: 232 GE 233 GE Sbjct: 227 GE 228
>gi|47117908|sp|Q9BZI1|IRX2_HUMAN Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2) Length = 471 Score = 39.7 bits (91), Expect = 9e-04 Identities = 20/61 (32%), Positives = 31/61 (50%) Query: 173 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232 E N Y T+ +I +A +T Q+ WF N R + KKENK+ + + ED + G Sbjct: 135 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDEDEG 194 Query: 233 E 233 + Sbjct: 195 D 195
>gi|7531125|sp|P56915|GSC_HUMAN Homeobox protein goosecoid Length = 252 Score = 39.3 bits (90), Expect = 0.001 Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 LE F +Y R ++A + L E ++++WF+NRR KW+++ + S E+SE Sbjct: 170 LENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKR------SSSEESE 222
>gi|47117871|sp|P78411|IRX5_HUMAN Iroquois-class homeodomain protein IRX-5 (Iroquois homeobox protein 5) (Homeodomain protein IRXB2) (IRX-2A) Length = 482 Score = 39.3 bits (90), Expect = 0.001 Identities = 45/189 (23%), Positives = 61/189 (32%), Gaps = 12/189 (6%) Query: 51 TYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQ 110 +Y YQ S S+ + +Y +L G S SGS G +P Sbjct: 2 SYPQGYLYQPSASLALYSCPAYSTSVISGPRTDEL-GRSSSGSAFSPYAGSTAFTAPSPG 60 Query: 111 YKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGA----------VYGSHXXXXXX 160 Y G A A Y Y M G YG Sbjct: 61 YNSHLQYGADPAAAAAAAFSSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNA 120 Query: 161 XXXXXXXLELE-KEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINS 219 L+ E N Y T+ +I +A +T Q+ WF N R + KKENK+ + Sbjct: 121 TRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWT 180 Query: 220 TQPSGEDSE 228 + ED E Sbjct: 181 PRNRSEDEE 189
>gi|6831676|sp|O15266|SHOX_HUMAN Short stature homeobox protein (Short stature homeobox containing protein) (Pseudoautosomal homeobox containing osteogenic protein) Length = 292 Score = 38.9 bits (89), Expect = 0.001 Identities = 18/45 (40%), Positives = 28/45 (62%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE 213 ELE+ F Y R E++ L L+E ++++WFQNRR K +K+ Sbjct: 131 ELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 175
>gi|6685480|sp|O15499|GSCL_HUMAN Homeobox protein goosecoid-like (GSC-2) Length = 205 Score = 37.7 bits (86), Expect = 0.003 Identities = 16/46 (34%), Positives = 27/46 (58%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LE F N+Y R +A + L E ++++WF+NRR KW+ + + Sbjct: 141 LEALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQKR 186
>gi|6174916|sp|P54821|PRRX1_HUMAN Paired mesoderm homeobox protein 1 (PRX-1) (Paired related homeobox protein 1) (Homeobox protein PHOX1) Length = 245 Score = 37.4 bits (85), Expect = 0.004 Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LE+ F Y R ++A + LTE ++++WFQNRR K+++ + Sbjct: 109 LERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNER 154
>gi|12230168|sp|Q9UBX0|HESX1_HUMAN Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf) Length = 185 Score = 37.4 bits (85), Expect = 0.004 Identities = 20/46 (43%), Positives = 27/46 (58%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LE F N Y R ++A L L E +I+IWFQNRR K K+ ++ Sbjct: 123 LENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHR 168
>gi|6093787|sp|O75360|PROP1_HUMAN Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary specific homeodomain factor) Length = 226 Score = 37.4 bits (85), Expect = 0.004 Identities = 18/47 (38%), Positives = 28/47 (59%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 +LE F N+Y R +A L+E +I++WFQNRR K +K+ + Sbjct: 83 QLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQER 129
>gi|12644475|sp|Q99811|PRRX2_HUMAN Paired mesoderm homeobox protein 2 (PRX-2) (Paired related homeobox protein 2) Length = 253 Score = 37.0 bits (84), Expect = 0.006 Identities = 16/46 (34%), Positives = 28/46 (60%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LE+ F Y R E+A + L+E ++++WFQNRR K+++ + Sbjct: 119 LERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER 164
>gi|37537960|sp|Q8NHV9|PEPP1_HUMAN Paired-like homeobox protein PEPP-1 (Ovary-, testis- and epididymis-expressed gene protein) Length = 184 Score = 35.8 bits (81), Expect = 0.012 Identities = 15/47 (31%), Positives = 28/47 (59%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 ELE F +Y R E+A L +TE ++++WF+N+R + ++ + Sbjct: 117 ELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQR 163
>gi|3287764|sp|O43186|CRX_HUMAN Cone-rod homeobox protein Length = 299 Score = 35.4 bits (80), Expect = 0.016 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 169 ELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKE-NKLINSTQPSGEDS 227 ELE F +Y R E+A + L E ++++WF+NRR K +++ + QP G + Sbjct: 53 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA 112 Query: 228 EAK 230 +A+ Sbjct: 113 KAR 115
>gi|47117873|sp|P78414|IRX1_HUMAN Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1) Length = 480 Score = 35.4 bits (80), Expect = 0.016 Identities = 19/60 (31%), Positives = 29/60 (48%) Query: 173 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232 E N Y T+ +I +A +T Q+ WF N R + KKENK+ + ++ A G Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFG 207
>gi|47117874|sp|P78415|IRX3_HUMAN Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1) Length = 501 Score = 35.0 bits (79), Expect = 0.021 Identities = 17/44 (38%), Positives = 24/44 (54%) Query: 173 EFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 E N Y T+ +I +A +T Q+ WF N R + KKENK+ Sbjct: 148 EHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKM 191
>gi|123402|sp|P09086|PO2F2_HUMAN POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer binding protein NF-A2) Length = 479 Score = 33.9 bits (76), Expect = 0.047 Identities = 18/45 (40%), Positives = 25/45 (55%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 LEK F N+ T + IA L + + I++WF NRR K K+ N Sbjct: 312 LEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRIN 356
>gi|28202257|sp|P14859|PO2F1_HUMAN POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1) Length = 743 Score = 33.1 bits (74), Expect = 0.081 Identities = 18/45 (40%), Positives = 25/45 (55%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 LEK F N+ T IA+ L + + I++WF NRR K K+ N Sbjct: 394 LEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRIN 438
>gi|417425|sp|P32242|OTX1_HUMAN Homeobox protein OTX1 Length = 354 Score = 33.1 bits (74), Expect = 0.081 Identities = 17/52 (32%), Positives = 30/52 (57%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQ 221 LE F RY R E+A + L E ++++WF+NRR K +++ + + T+ Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTK 104
>gi|417427|sp|P32243|OTX2_HUMAN Homeobox protein OTX2 Length = 289 Score = 32.7 bits (73), Expect = 0.11 Identities = 16/46 (34%), Positives = 27/46 (58%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 LE F RY R E+A + L E ++++WF+NRR K +++ + Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ 98
>gi|2495290|sp|Q15475|SIX1_HUMAN Homeobox protein SIX1 (Sine oculis homeobox homolog 1) Length = 284 Score = 32.3 bits (72), Expect = 0.14 Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 209 L + + N Y + R + E+A A LT Q+ WF+NRR + Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
>gi|12230598|sp|Q9NPC8|SIX2_HUMAN Homeobox protein SIX2 (Sine oculis homeobox homolog 2) Length = 291 Score = 32.3 bits (72), Expect = 0.14 Identities = 15/40 (37%), Positives = 23/40 (57%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 209 L + + N Y + R + E+A A LT Q+ WF+NRR + Sbjct: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
>gi|28201861|sp|Q9UKI9|PO2F3_HUMAN POU domain, class 2, transcription factor 3 (Octamer-binding transcription factor 11) (Oct-11) (Transcription factor Skn-1) (PLA-1 protein) Length = 436 Score = 32.3 bits (72), Expect = 0.14 Identities = 17/47 (36%), Positives = 24/47 (51%) Query: 168 LELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKEN 214 L LEK F N + IA L + + +++WF NRR K K+ N Sbjct: 294 LTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRIN 340
>gi|60416412|sp|P48742|LHX1_HUMAN LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) Length = 406 Score = 32.0 bits (71), Expect = 0.18 Identities = 15/36 (41%), Positives = 22/36 (61%) Query: 181 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 TR R ++A L R I++WFQNRR K ++ +L Sbjct: 206 TRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQL 241
>gi|18202938|sp|Q9H2C1|LHX5_HUMAN LIM/homeobox protein Lhx5 Length = 402 Score = 32.0 bits (71), Expect = 0.18 Identities = 15/36 (41%), Positives = 22/36 (61%) Query: 181 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 TR R ++A L R I++WFQNRR K ++ +L Sbjct: 206 TRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQL 241
>gi|12230612|sp|Q9UIU6|SIX4_HUMAN Homeobox protein SIX4 (Sine oculis homeobox homolog 4) Length = 760 Score = 32.0 bits (71), Expect = 0.18 Identities = 19/68 (27%), Positives = 34/68 (50%), Gaps = 4/68 (5%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK----ENKLINSTQPSGE 225 L++ + NRY + + +A L+ Q+ WF+NRR + + ++K + PS E Sbjct: 217 LKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSKSESDGNPSTE 276 Query: 226 DSEAKAGE 233 D +K E Sbjct: 277 DESSKGHE 284
>gi|18202510|sp|Q15911|ATBF1_HUMAN Alpha-fetoprotein enhancer binding protein (AT motif-binding factor) (AT-binding transcription factor 1) Length = 3703 Score = 32.0 bits (71), Expect = 0.18 Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 4/61 (6%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 L+ F N Y +++N L L R I +WFQN R K +K + Q G+D E Sbjct: 2257 LQDFFDANAYPKDDEFEQLSNLLNLPTRVIVVWFQNARQKARKNYE----NQGEGKDGER 2312 Query: 230 K 230 + Sbjct: 2313 R 2313
Score = 29.6 bits (65), Expect = 0.89 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 5/45 (11%) Query: 173 EFHFNRYL-----TRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 E + +YL TR+ IA+ + L +R +++WFQN R + +K Sbjct: 2654 EILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQNTRARERK 2698
Score = 29.3 bits (64), Expect = 1.2 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 8/48 (16%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKL-------INSTQPSGEDSE 228 + N + L +R +++WFQN R K +K++KL IN T G +E Sbjct: 2979 LGNDIGLPKRVVQVWFQNARAK-EKKSKLSMAKHFGINQTSYEGPKTE 3025
Score = 26.9 bits (58), Expect = 5.8 Identities = 14/46 (30%), Positives = 24/46 (52%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 L + F N + + E+A+ L ++ IK WF+N K ++ NK Sbjct: 2160 LRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNK 2205
>gi|20978495|sp|Q96A47|ISL2_HUMAN Insulin gene enhancer protein ISL-2 (Islet-2) Length = 359 Score = 31.2 bits (69), Expect = 0.31 Identities = 13/28 (46%), Positives = 20/28 (71%) Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQ 221 L+ R I++WFQN+R K KK++ L+ Q Sbjct: 230 LSPRVIRVWFQNKRCKDKKKSILMKQLQ 257
>gi|730281|sp|P40426|PBX3_HUMAN Pre-B-cell leukemia transcription factor-3 (Homeobox protein PBX3) Length = 434 Score = 30.4 bits (67), Expect = 0.52 Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 177 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 N Y + + E+A +T Q+ WF N+R+++KK Sbjct: 260 NPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK 295
>gi|47606423|sp|P61371|ISL1_HUMAN Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606425|sp|P61373|ISL1_MESAU Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606424|sp|P61372|ISL1_MOUSE Insulin gene enhancer protein ISL-1 (Islet-1) gi|47606422|sp|P61374|ISL1_RAT Insulin gene enhancer protein ISL-1 (Islet-1) Length = 349 Score = 30.0 bits (66), Expect = 0.68 Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQ 221 L+ R I++WFQN+R K KK + ++ Q Sbjct: 220 LSPRVIRVWFQNKRCKDKKRSIMMKQLQ 247
>gi|20141754|sp|P41778|PBX1_MOUSE Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1) gi|730279|sp|P40424|PBX1_HUMAN Pre-B-cell leukemia transcription factor-1 (Homeobox protein PBX1) (Homeobox protein PRL) Length = 430 Score = 29.6 bits (65), Expect = 0.89 Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 177 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 N Y + + E+A +T Q+ WF N+R+++KK Sbjct: 258 NPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 293
>gi|1352729|sp|P40425|PBX2_HUMAN Pre-B-cell leukemia transcription factor-2 (Homeobox protein PBX2) (G17 protein) Length = 430 Score = 29.6 bits (65), Expect = 0.89 Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 177 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 N Y + + E+A +T Q+ WF N+R+++KK Sbjct: 269 NPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK 304
>gi|28380240|sp|Q9C0A1|ZFHX2_HUMAN Zinc finger homeobox protein 2 Length = 1427 Score = 29.6 bits (65), Expect = 0.89 Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAG 232 +A+ L L R + +WFQN R K +K N + P+G + +G Sbjct: 483 LASLLGLASRVVVVWFQNARQKARK-NACEGGSMPTGGGTGGASG 526
Score = 28.1 bits (61), Expect = 2.6 Identities = 14/35 (40%), Positives = 19/35 (54%) Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 L +R I++WFQN R K KK + +G SE Sbjct: 959 LPKRVIQVWFQNARAKEKKAKLQGTAAGSTGGSSE 993
>gi|12643415|sp|Q9UBR4|LHX3_HUMAN LIM/homeobox protein Lhx3 Length = 397 Score = 29.3 bits (64), Expect = 1.2 Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 182 RRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 R R ++++ L R +++WFQNRR K K+ K Sbjct: 184 RHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217
>gi|27923801|sp|Q8TE12|LMX1A_HUMAN LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1) Length = 382 Score = 29.3 bits (64), Expect = 1.2 Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 182 RRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 R+ R +A L+ R +++WFQN+R K KK Sbjct: 222 RKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252
>gi|20138668|sp|Q969G2|LHX4_HUMAN LIM/homeobox protein Lhx4 Length = 367 Score = 29.3 bits (64), Expect = 1.2 Identities = 13/34 (38%), Positives = 21/34 (61%) Query: 182 RRRRIEIANALCLTERQIKIWFQNRRMKWKKENK 215 R R ++++ L R +++WFQNRR K K+ K Sbjct: 161 RHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 194
>gi|8247930|sp|O60663|LMX1B_HUMAN LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2) Length = 379 Score = 29.3 bits (64), Expect = 1.2 Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 182 RRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 R+ R +A L+ R +++WFQN+R K KK Sbjct: 223 RKVRETLAAETGLSVRVVQVWFQNQRAKMKK 253
>gi|8247936|sp|P50458|LHX2_HUMAN LIM/homeobox protein Lhx2 (Homeobox protein LH-2) Length = 406 Score = 28.9 bits (63), Expect = 1.5 Identities = 10/26 (38%), Positives = 19/26 (73%) Query: 187 EIANALCLTERQIKIWFQNRRMKWKK 212 ++A LT+R +++WFQN R K+++ Sbjct: 298 QLAQKTGLTKRVLQVWFQNARAKFRR 323
>gi|6094293|sp|O95343|SIX3_HUMAN Homeobox protein SIX3 (Sine oculis homeobox homolog 3) Length = 332 Score = 28.9 bits (63), Expect = 1.5 Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%) Query: 179 YLTRRRRIEIANALCLTERQIKIWFQNRRMKWK---KENKLIN-STQPSGEDSEAKAG 232 Y ++ E+A A LT Q+ WF+NRR + + +N+L + + PSG S A+ G Sbjct: 230 YPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLAEPG 287
>gi|127819|sp|P22736|NR4A1_HUMAN Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59) Length = 598 Score = 28.9 bits (63), Expect = 1.5 Identities = 37/129 (28%), Positives = 48/129 (37%), Gaps = 28/129 (21%) Query: 8 PTFPGSLPSGQ---DSFLGQLP--LYQAGYDALRPFPASYGASSLPDKTYTSPC---FYQ 59 P P +LPS D + G+ LYQ AS ASS + TSP F Sbjct: 44 PAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSSASSSASSTSSSSATSPASASFKF 103 Query: 60 QSNSVLAC--------------NRASYEYGASCFYSDKDLSGASPSGSGKQRGP--GDYL 103 + V C + S YG+ C S ++PS Q P G + Sbjct: 104 EDFQVYGCYPGPLSGPVDEALSSSGSDYYGSPCSAP----SPSTPSFQPPQLSPWDGSFG 159 Query: 104 HFSPEQQYK 112 HFSP Q Y+ Sbjct: 160 HFSPSQTYE 168
>gi|1709437|sp|Q03052|PO3F1_HUMAN POU domain, class 3, transcription factor 1 (Octamer-binding transcription factor 6) (Oct-6) (POU-domain transcription factor SCIP) Length = 448 Score = 28.9 bits (63), Expect = 1.5 Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGED 226 +A++L L + +++WF NRR K K+ + P +D Sbjct: 369 LADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDD 407
>gi|12643346|sp|Q9NQ69|LHX9_HUMAN LIM/homeobox protein Lhx9 Length = 388 Score = 28.9 bits (63), Expect = 1.5 Identities = 10/26 (38%), Positives = 19/26 (73%) Query: 187 EIANALCLTERQIKIWFQNRRMKWKK 212 ++A LT+R +++WFQN R K+++ Sbjct: 290 QLAQKTGLTKRVLQVWFQNARAKFRR 315
>gi|37999770|sp|Q9BYU1|PBX4_HUMAN Pre-B-cell leukemia transcription factor-4 (Homeobox protein PBX4) Length = 330 Score = 28.9 bits (63), Expect = 1.5 Identities = 13/36 (36%), Positives = 21/36 (58%) Query: 177 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKK 212 N Y + + E+A LT Q+ WF N+R+++KK Sbjct: 191 NPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKK 226
>gi|20531996|sp|Q8WXK4|AS12_HUMAN Ankyrin repeat and SOCS box protein 12 (ASB-12) Length = 308 Score = 28.9 bits (63), Expect = 1.5 Identities = 26/98 (26%), Positives = 38/98 (38%), Gaps = 19/98 (19%) Query: 54 SPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKP 113 +P F S+ L C R E +GASP GS Y + SP Sbjct: 99 TPLFTAVSHGHLDCVRVLLE------------AGASPGGS-------IYNNCSPVLTAAR 139 Query: 114 DSSSGQGKALHDEGADRKYTSPVYPWMQRMNSCAGAVY 151 D + + L D GA+ + + W + SC+G +Y Sbjct: 140 DGAVAILQELLDHGAEANVKAKLPVWASNIASCSGPLY 177
>gi|28201884|sp|P78424|PO6F2_HUMAN POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor-1) (RPF-1) Length = 684 Score = 28.9 bits (63), Expect = 1.5 Identities = 14/54 (25%), Positives = 24/54 (44%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPS 223 L F N + + + EIA L +++WF N+R K K + +P+ Sbjct: 615 LNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHEPA 668
>gi|2495306|sp|Q14863|PO6F1_HUMAN POU domain, class 6, transcription factor 1 (mPOU homeobox protein) (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5 protein) Length = 301 Score = 28.5 bits (62), Expect = 2.0 Identities = 16/47 (34%), Positives = 21/47 (44%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKL 216 L F N T + EIA L +++WF NRR K +KL Sbjct: 249 LNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKL 295
>gi|12643905|sp|Q9UP79|ATS8_HUMAN ADAMTS-8 precursor (A disintegrin and metalloproteinase with thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8) (METH-2) (METH-8) Length = 890 Score = 28.5 bits (62), Expect = 2.0 Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 8/69 (11%) Query: 86 SGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVYPWMQRMNS 145 +G+ P G GPG H E P+ + K + D G +P PW + + Sbjct: 491 NGSLPWADGTPCGPG---HLCSEGSCLPEEEVERPKPVVDGG-----WAPWGPWGECSRT 542 Query: 146 CAGAVYGSH 154 C G V SH Sbjct: 543 CGGGVQFSH 551
>gi|28202258|sp|P20265|PO3F2_HUMAN POU domain, class 3, transcription factor 2 (Nervous-system specific octamer-binding transcription factor N-Oct-3) (Brain-specific homeobox/POU domain protein 2) (Brain-2) (Brn-2 protein) Length = 443 Score = 28.1 bits (61), Expect = 2.6 Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGED 226 +A++L L + +++WF NRR K K+ T P ED Sbjct: 387 LADSLQLEKEVVRVWFCNRRQKEKRMTP-PGGTLPGAED 424
>gi|123408|sp|P28069|PIT1_HUMAN Pituitary-specific positive transcription factor 1 (Pit-1) (Growth hormone factor 1) (GHF-1) Length = 291 Score = 28.1 bits (61), Expect = 2.6 Identities = 13/51 (25%), Positives = 26/51 (50%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINST 220 LE+ F + + + +A L L + +++WF NRR + K+ +N + Sbjct: 229 LERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQS 279
>gi|20138948|sp|Q04721|NOTC2_HUMAN Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) Length = 2471 Score = 27.7 bits (60), Expect = 3.4 Identities = 28/108 (25%), Positives = 39/108 (36%), Gaps = 31/108 (28%) Query: 10 FPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLACNR 69 FP ++ QD + Q L A PFPAS G P ++ Sbjct: 2353 FPTAMMPQQDGQVAQTIL-----PAYHPFPASVGKYPTPPSQHS---------------- 2391 Query: 70 ASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS 117 Y+ + + +PS SG +G YL SPE + SSS Sbjct: 2392 ----------YASSNAAERTPSHSGHLQGEHPYLTPSPESPDQWSSSS 2429
>gi|400659|sp|Q01860|PO5F1_HUMAN POU domain, class 5, transcription factor 1 (Octamer-binding transcription factor 3) (Oct-3) (Oct-4) Length = 360 Score = 27.3 bits (59), Expect = 4.4 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 IA L L + +++WF NRR K K+ +S ED EA Sbjct: 263 IAQQLGLEKDVVRVWFCNRRQKGKRS----SSDYAQREDFEA 300
>gi|730052|sp|Q00325|MPCP_HUMAN Phosphate carrier protein, mitochondrial precursor (PTP) (OK/SW-cl.48) Length = 362 Score = 27.3 bits (59), Expect = 4.4 Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 84 DLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQ 119 DL +SP +G+ R P + + E+QY D SG+ Sbjct: 28 DLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYGSGR 63
>gi|28201858|sp|Q06416|PO5L_HUMAN POU domain, class 5, transcription factor 1-like protein 1 (Octamer binding protein 3-like) Length = 359 Score = 27.3 bits (59), Expect = 4.4 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 IA L L + +++WF NRR K K+ +S ED EA Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRS----SSDYAQREDFEA 299
>gi|12230578|sp|O95475|SIX6_HUMAN Homeobox protein SIX6 (Sine oculis homeobox homolog 6) (Optic homeobox 2) (Homeodomain protein OPTX2) Length = 246 Score = 27.3 bits (59), Expect = 4.4 Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 179 YLTRRRRIEIANALCLTERQIKIWFQNRRMK 209 Y ++ E+A A LT Q+ WF+NRR + Sbjct: 152 YPNPSKKRELAQATGLTPTQVGNWFKNRRQR 182
>gi|28201859|sp|Q9BZV7|PO5M_HUMAN POU domain, class 5, transcription factor 1-like protein 2 Length = 359 Score = 27.3 bits (59), Expect = 4.4 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 4/42 (9%) Query: 188 IANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEA 229 IA L L + +++WF NRR K K+ +S ED EA Sbjct: 262 IAQQLGLEKDVVRVWFCNRRQKGKRS----SSDYAQREDFEA 299
>gi|8134548|sp|Q9UPM6|LHX61_HUMAN LIM/homeobox protein Lhx6.1 (Lhx6) Length = 363 Score = 27.3 bits (59), Expect = 4.4 Identities = 14/38 (36%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 187 EIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSG 224 ++A+ L+ R I++WFQN R + KK + PSG Sbjct: 251 KLADMTGLSRRVIQVWFQNCRARHKKHTPQ-HPVPPSG 287
>gi|1345629|sp|P49335|PO3F4_HUMAN POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) Length = 361 Score = 26.9 bits (58), Expect = 5.8 Identities = 10/25 (40%), Positives = 18/25 (72%) Query: 188 IANALCLTERQIKIWFQNRRMKWKK 212 +A++L L + +++WF NRR K K+ Sbjct: 311 LADSLQLEKEVVRVWFCNRRQKEKR 335
>gi|17371773|sp|Q92934|BAD_HUMAN Bcl2-antagonist of cell death (BAD) (Bcl-2 binding component 6) (Bcl-XL/Bcl-2 associated death promoter) (Bcl-2-like 8 protein) Length = 168 Score = 26.9 bits (58), Expect = 5.8 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 3/39 (7%) Query: 86 SGASPSGSGK--QRGPGDYLHFSPEQQYKPDSSSGQGKA 122 +G PSGSGK ++ PG L + QQ +P SSS G A Sbjct: 27 AGDGPSGSGKHHRQAPG-LLWDASHQQEQPTSSSHHGGA 64
>gi|2506534|sp|P20264|PO33_HUMAN POU domain, class 3, transcription factor 3 (Brain-specific homeobox/POU domain protein 1) (Brain-1) (Brn-1 protein) Length = 500 Score = 26.9 bits (58), Expect = 5.8 Identities = 10/25 (40%), Positives = 18/25 (72%) Query: 188 IANALCLTERQIKIWFQNRRMKWKK 212 +A++L L + +++WF NRR K K+ Sbjct: 439 LADSLQLEKEVVRVWFCNRRQKEKR 463
>gi|46396941|sp|Q8N196|SIX5_HUMAN Homeobox protein SIX5 (DM locus-associated homeodomain protein) Length = 739 Score = 26.9 bits (58), Expect = 5.8 Identities = 12/33 (36%), Positives = 18/33 (54%) Query: 177 NRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 209 NRY T + +A L+ Q+ WF+NRR + Sbjct: 223 NRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQR 255
>gi|44889075|sp|Q9H4I2|ZHX3_HUMAN Zinc fingers and homeoboxes protein 3 (Triple homeobox 1 protein) Length = 956 Score = 26.6 bits (57), Expect = 7.6 Identities = 14/40 (35%), Positives = 17/40 (42%) Query: 194 LTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233 +T R+I WF RR K E S E+ EA E Sbjct: 651 MTRREIDSWFSERRKKVNAEETKKAEENASQEEEEAAEDE 690
Score = 26.6 bits (57), Expect = 7.6 Identities = 13/40 (32%), Positives = 19/40 (47%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMK 209 L+ FH Y T+ + E Q+KIWF +R+K Sbjct: 319 LKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLK 358
>gi|21759444|sp|Q9NSC7|SI7A_HUMAN Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A) Length = 600 Score = 26.6 bits (57), Expect = 7.6 Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 3/40 (7%) Query: 196 ERQIKIWFQNRRMKWK---KENKLINSTQPSGEDSEAKAG 232 E Q K+ +R WK KE ++N+ P G+D+ +G Sbjct: 110 EEQDKVPHTAQRAAWKSPEKEKTMVNTLSPRGQDAGMASG 149
>gi|133326|sp|P24928|RPB1_HUMAN DNA-directed RNA polymerase II largest subunit (RPB1) Length = 1970 Score = 26.6 bits (57), Expect = 7.6 Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 6/111 (5%) Query: 7 NPTFPGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYTSPCFYQQSNSVLA 66 +PT P P + Q P Y + P SY +S P+ + TSP + S S Sbjct: 1594 SPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTS-PNYSPTSPSYSPTSPSYSP 1652 Query: 67 CNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSS 117 + + S + S SPS S P + Y P S S Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTSPS 1698
>gi|17376322|sp|Q14161|GIT2_HUMAN ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2) Length = 759 Score = 26.6 bits (57), Expect = 7.6 Identities = 34/124 (27%), Positives = 50/124 (40%), Gaps = 22/124 (17%) Query: 2 SSYFVNPTFPGSLP-------SGQDSFL--GQLPLYQAGYDALRPFPASYGASSLPDKTY 52 SS P+ GS P SGQ +L G+ + L+PFPA G S+L + Sbjct: 499 SSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQPFPAHIGRSALVTSSS 558 Query: 53 TSPCF-----YQQSNSVLACNR-----ASYEYGASCFYSDKDLSGASPSGSGKQRG---P 99 + P F + + S +R ++ E +D + G S G+QR P Sbjct: 559 SLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWP 618 Query: 100 GDYL 103 GD L Sbjct: 619 GDGL 622
>gi|544357|sp|P35637|FUS_HUMAN RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein) Length = 526 Score = 26.6 bits (57), Expect = 7.6 Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 11/90 (12%) Query: 42 YGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSD--KDLSGA---SPSGSGKQ 96 YG+S +Y Y A + S YG+S S + SG+ PS G+Q Sbjct: 81 YGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQ 140 Query: 97 RGPGDYLHFSPEQ------QYKPDSSSGQG 120 + G ++P Q QY S G G Sbjct: 141 QSYGQQQSYNPPQGYGQQNQYNSSSGGGGG 170
>gi|13626594|sp|Q15596|NCOA2_HUMAN Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) Length = 1464 Score = 26.6 bits (57), Expect = 7.6 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 15 PSGQDSFLGQLPLYQAGYDALRPFPASYGASSLPDKTYT 53 PSG + + + QA PFP +YG S PD +T Sbjct: 1279 PSGMPATMSNPRIPQANAQQF-PFPPNYGISQQPDPGFT 1316
>gi|25453452|sp|Q16236|NF2L2_HUMAN Nuclear factor erythroid 2 related factor 2 (NF-E2 related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1) Length = 605 Score = 26.6 bits (57), Expect = 7.6 Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 7/75 (9%) Query: 53 TSPCFYQQSNSVLACNRASYEYGASCF-YSDKDLSGA-SPSGSGKQRGPGDYLHFSPEQQ 110 TSP +SV S YG + SD ++ S GS KQ GP +H S + Sbjct: 350 TSPSVASPEHSV-----ESSSYGDTLLGLSDSEVEELDSAPGSVKQNGPKTPVHSSGDMV 404 Query: 111 YKPDSSSGQGKALHD 125 S GQ +HD Sbjct: 405 QPLSPSQGQSTHVHD 419
>gi|17368438|sp|Q13064|MKR3_HUMAN Makorin 3 (Zinc finger protein 127) (RING finger protein 63) Length = 507 Score = 26.6 bits (57), Expect = 7.6 Identities = 38/136 (27%), Positives = 54/136 (39%), Gaps = 29/136 (21%) Query: 35 LRPFPASYGA---SSLPDKTYTSPCFYQQSNSVLACN---RASYEYGASCFYSDKDLSG- 87 LRP PAS G S LP ++ S + +Q + C + G +C YS DLSG Sbjct: 72 LRPAPASGGGAWPSPLPSRS--SGIWTKQ----IICRYYIHGQCKEGENCRYSH-DLSGR 124 Query: 88 -------ASPSGSGKQRGPGDYLHFSPEQQ---YKPDSSSGQGKALHDEGADRKYTSPVY 137 SP G+ GP H P Q P ++S + A+R + Sbjct: 125 KMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFFE--- 181 Query: 138 PWMQRMNSCAGAVYGS 153 +R N+ GA G+ Sbjct: 182 --AERDNADRGAAGGA 195
>gi|44888551|sp|Q9UKY1|ZHX1_HUMAN Zinc fingers and homeoboxes protein 1 Length = 873 Score = 26.2 bits (56), Expect = 9.9 Identities = 10/15 (66%), Positives = 12/15 (80%) Query: 195 TERQIKIWFQNRRMK 209 TE QIKIWF +R+K Sbjct: 324 TEEQIKIWFSAQRLK 338
>gi|13431548|sp|Q92830|GCNL2_HUMAN General control of amino acid synthesis protein 5-like 2 (Histone acetyltransferase GCN5) (hsGCN5) (STAF97) Length = 837 Score = 26.2 bits (56), Expect = 9.9 Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 8/72 (11%) Query: 10 FPGSLPSGQDSFLG-QLPLYQAGYDA-------LRPFPASYGASSLPDKTYTSPCFYQQS 61 FP L ++ G P++++G+ L P PAS A+ +P SP S Sbjct: 356 FPKFLSMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGS 415 Query: 62 NSVLACNRASYE 73 NS L+ + A E Sbjct: 416 NSSLSLDSAGAE 427
>gi|38503102|sp|Q8WXU2|DYX1_HUMAN Dyslexia susceptibility 1 candidate gene 1 protein Length = 420 Score = 26.2 bits (56), Expect = 9.9 Identities = 16/59 (27%), Positives = 26/59 (44%) Query: 170 LEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSE 228 LE + R +++I+ LC E+QIK + + K N + P G +SE Sbjct: 159 LEAWKEYQRKAEEQKKIQREEKLCQKEKQIKEGRKKIKYKSLTRNLASRNLAPKGRNSE 217
>gi|48428608|sp|Q12789|T3C1_HUMAN General transcription factor 3C polypeptide 1 (Transcription factor IIIC-alpha subunit) (TF3C-alpha) (TFIIIC 220 kDa subunit) (TFIIIC220) (TFIIIC box B-binding subunit) Length = 2109 Score = 26.2 bits (56), Expect = 9.9 Identities = 13/42 (30%), Positives = 22/42 (52%) Query: 82 DKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKAL 123 D LS +S S SG+ + + + +P + Y P G G++L Sbjct: 750 DSQLSASSRSESGRMKKSDNKMGITPLRNYHPIVVPGLGRSL 791
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.315 0.131 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 620,191 Number of Sequences: 164271 Number of extensions: 30588 Number of successful extensions: 80 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 1 Number of HSP's that attempted gapping in prelim test: 48 Number of HSP's gapped (non-prelim): 31 length of query: 233 length of database: 6,424,444 effective HSP length: 92 effective length of query: 141 effective length of database: 5,329,184 effective search space: 751414944 effective search space used: 751414944 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 56 (26.2 bits)