BLASTP 2.2.10 [Oct-19-2004]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1111084957-538-2578068731.BLASTQ4

Query= FGENESH_gen4 25 exon (s) 447041  - 499237  1144 aa,
chain +
         (1144 letters)


Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples 
           2,367,365 sequences; 802,797,248 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs

Taxonomy reports

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51471105|ref|XP_497341.1|  PREDICTED: similar to submaxil...   735   0.0   
gi|4505285|ref|NP_002448.1|  mucin 2 [Homo sapiens] >gi|4541...   270   1e-71 
gi|186396|gb|AAA59163.1|  mucin                                   270   1e-71 
gi|2135765|pir||A43932  mucin 2 precursor, intestinal - huma...   270   1e-71 
gi|17384254|emb|CAC83674.1|  mucin 5 [Homo sapiens]               268   4e-71 
gi|3192971|gb|AAC19168.1|  gastric mucin [Homo sapiens]           265   3e-70 
gi|51470790|ref|XP_039877.9|  PREDICTED: mucin 5, subtype B,...   265   4e-70 
gi|11275568|gb|AAG33673.1|  mucin 5B [Homo sapiens]               265   4e-70 
gi|23821885|sp|Q9HC84|MU5B_HUMAN  Mucin 5B precursor (Mucin ...   265   4e-70 
gi|4038587|emb|CAA06167.1|  mucin [Homo sapiens]                  263   2e-69 
gi|7512452|pir||JE0095  gastric mucin MUC5AC precursor - human    261   8e-69 
gi|7513163|pir||JE0352  mucin MUC5B, tracheobronchial - huma...   259   2e-68 
gi|4507907|ref|NP_000543.1|  von Willebrand factor precursor...   250   1e-65 
gi|37947|emb|CAA27972.1|  unnamed protein product [Homo sapi...   250   1e-65 
gi|37942|emb|CAA27765.1|  unnamed protein product [Homo sapi...   247   1e-64 
gi|1362802|pir||S56015  gastric mucin MUC5AC - human (fragme...   220   1e-56 
gi|34765003|gb|AAQ82434.1|  mucin glycoprotein [Homo sapiens]     203   2e-51 
gi|51493054|ref|XP_290540.5|  PREDICTED: mucin 6, gastric [H...   201   5e-51 
gi|3123852|gb|AAC15950.1|  mucin [Homo sapiens]                   196   3e-49 
gi|51492791|ref|XP_379967.2|  PREDICTED: similar to SCO-spon...   189   2e-47 
gi|51466599|ref|XP_376720.2|  PREDICTED: KIAA0543 protein [H...   189   2e-47 
gi|340361|gb|AAB59512.1|  von Willebrand factor prepropeptide     181   8e-45 
gi|4503681|ref|NP_003881.1|  Fc fragment of IgG binding prot...   162   3e-39 
gi|5080756|gb|AAD39266.1|  Human Fc gamma BP [AA 1-2843] [Ho...   162   3e-39 
gi|15722000|gb|AAL04415.1|  zonadhesin splice variant 2 [Hom...   148   7e-35 
gi|15721999|gb|AAL04414.1|  zonadhesin splice variant 4 [Hom...   148   7e-35 
gi|15721998|gb|AAL04413.1|  zonadhesin splice variant 6 [Hom...   148   7e-35 
gi|15721997|gb|AAL04412.1|  zonadhesin splice variant 5 [Hom...   148   7e-35 
gi|15721996|gb|AAL04411.1|  zonadhesin splice variant 3 [Hom...   148   7e-35 
gi|15721995|gb|AAL04410.1|  zonadhesin splice variant 1 [Hom...   148   7e-35 
gi|4885627|ref|NP_005413.1|  tectorin alpha precursor [Homo ...   147   9e-35 
gi|27881494|ref|NP_775082.1|  zonadhesin isoform 6 [Homo sap...   146   3e-34 
gi|27881492|ref|NP_775081.1|  zonadhesin isoform 5 [Homo sap...   146   3e-34 
gi|27881490|ref|NP_775080.1|  zonadhesin isoform 4 [Homo sap...   146   3e-34 
gi|27881488|ref|NP_775079.1|  zonadhesin isoform 2 [Homo sap...   146   3e-34 
gi|27881486|ref|NP_775078.1|  zonadhesin isoform 1 [Homo sap...   146   3e-34 
gi|16554449|ref|NP_003377.1|  zonadhesin isoform 3 [Homo sap...   146   3e-34 
gi|4321127|gb|AAD15624.1|  IgG Fc binding protein [AA 4671-5...   133   2e-30 
gi|553810|gb|AAA61295.1|  von Willebrand factor                   129   3e-29 
gi|3135306|gb|AAC78790.1|  zonadhesin [Homo sapiens]              122   3e-27 
gi|34534638|dbj|BAC87067.1|  unnamed protein product [Homo s...   115   5e-25 
gi|34535476|dbj|BAC87330.1|  unnamed protein product [Homo s...   114   9e-25 
gi|42659821|ref|XP_291816.4|  PREDICTED: otogelin [Homo sapi...   114   9e-25 
gi|37360934|dbj|BAC98376.1|  KIAA2036 protein [Homo sapiens]      114   2e-24 
gi|51105836|gb|EAL24436.1|  KIAA2036 protein [Homo sapiens]       113   2e-24 
gi|4322670|gb|AAD16120.1|  dentin phosphoryn [Homo sapiens]       110   2e-23 
gi|11036632|ref|NP_055023.1|  dentin sialophosphoprotein pre...   107   1e-22 
gi|51105835|gb|EAL24435.1|  FLJ45737 protein [Homo sapiens]       106   3e-22 
gi|51493056|ref|XP_495859.1|  PREDICTED: similar to mucin 5 ...   101   8e-21 
gi|38173826|gb|AAH60868.1|  BMPER protein [Homo sapiens] >gi...    99   7e-20 
gi|51105884|gb|EAL24468.1|  BMP-binding endothelial regulato...    99   7e-20 
gi|18916818|dbj|BAB85551.1|  KIAA1965 protein [Homo sapiens]       99   7e-20 
gi|13383506|gb|AAK21011.1|  zonadhesin [Homo sapiens]              92   5e-18 
gi|1932794|gb|AAC51208.1|  zonadhesin [Homo sapiens]               92   8e-18 
gi|28557150|dbj|BAC57496.1|  hornerin [Homo sapiens]               83   3e-15 
gi|55665870|emb|CAH70026.1|  novel S-100\/ICaBP type calcium...    79   4e-14 
gi|57546919|tpd|FAA00004.1|  TPA: Hornerin [Homo sapiens]          79   4e-14 
gi|59939295|gb|AAX12417.1|  ifapsoriasin [Homo sapiens]            79   4e-14 
gi|40795897|gb|AAR91619.1|  hornerin precursor [Homo sapiens]      79   4e-14 
gi|186398|gb|AAA59164.1|  MUC2                                     71   1e-11 
gi|2130546|gb|AAC51344.1|  mucin [Homo sapiens]                    70   2e-11 
gi|2370133|emb|CAA70926.1|  mucin [Homo sapiens]                   70   2e-11 
gi|2290534|gb|AAB65151.1|  sublingual gland mucin [Homo sapi...    67   2e-10 
gi|51464403|ref|XP_068121.3|  PREDICTED: similar to CG15920-...    61   1e-08 
gi|54035079|gb|AAH34690.1|  Loricrin [Homo sapiens]                60   3e-08 
gi|4557725|ref|NP_000418.1|  loricrin [Homo sapiens] >gi|214...    60   3e-08 
gi|49168594|emb|CAG38792.1|  LOR [Homo sapiens]                    60   3e-08 
gi|56204896|emb|CAI19560.1|  loricrin [Homo sapiens]               60   3e-08 
gi|55961914|emb|CAI17705.1|  chromosome 6 open reading frame...    57   2e-07 
gi|55961891|emb|CAI18008.1|  chromosome 6 open reading frame...    57   2e-07 
gi|21748896|dbj|BAC03505.1|  unnamed protein product [Homo s...    56   4e-07 
gi|56205087|emb|CAI19595.1|  filaggrin [Homo sapiens] >gi|60...    55   1e-06 
gi|190394|gb|AAA63243.1|  profilaggrin                             55   1e-06 
gi|3334747|emb|CAA04738.1|  MUC5AC protein [Homo sapiens] >g...    54   1e-06 
gi|2135763|pir||A57534  mucin 5AC (clone L31) - human (fragm...    54   2e-06 
gi|46397621|sp|P98088|MU5A_HUMAN  Mucin 5AC (Mucin 5 subtype...    54   2e-06 
gi|190400|gb|AAA63246.1|  profilaggrin                             53   3e-06 
gi|37181955|gb|AAQ88781.1|  KMQK697 [Homo sapiens]                 52   5e-06 
gi|56206538|emb|CAI18456.1|  chromosome 6 open reading frame...    52   5e-06 
gi|631314|pir||S42718  nuclear pore complex protein nup153 -...    52   7e-06 
gi|55957596|emb|CAI16394.1|  nucleoporin 153kDa [Homo sapien...    52   7e-06 
gi|31418202|gb|AAH52965.1|  Nucleoporin 153kDa [Homo sapiens]      52   7e-06 
gi|21707329|gb|AAH33831.1|  Unknown (protein for IMAGE:38526...    50   2e-05 
gi|107415|pir||A35938  profilaggrin - human (fragments)            50   3e-05 
gi|29653|emb|CAA45535.1|  putative oncogene [Homo sapiens] >...    50   3e-05 
gi|56208558|emb|CAI20354.1|  OTTHUMP00000028832 [Homo sapien...    50   3e-05 
gi|57208869|emb|CAI41111.1|  OTTHUMP00000064563 [Homo sapien...    50   3e-05 
gi|57208867|emb|CAI41109.1|  nucleoporin 214kDa [Homo sapiens]     50   3e-05 
gi|51476025|ref|XP_039385.2|  PREDICTED: KIAA1093 protein [H...    50   3e-05 
gi|41016075|dbj|BAD07398.1|  KIAA0023 splice variant 1 [Homo...    50   3e-05 
gi|38258268|sp|Q9UPQ9|K1093_HUMAN  Protein KIAA1093                50   3e-05 
gi|14133235|dbj|BAA83045.2|  KIAA1093 protein [Homo sapiens]       50   3e-05 
gi|60688059|gb|AAH45620.2|  NUP214 protein [Homo sapiens]          49   5e-05 
gi|2654425|gb|AAB87728.1|  dentin matrix protein 1                 49   5e-05 
gi|4758172|ref|NP_004398.1|  dentin matrix acidic phosphopro...    49   8e-05 
gi|18490128|gb|AAH22258.1|  VWF protein [Homo sapiens]             48   1e-04 
gi|28958131|gb|AAH47455.1|  DDX4 protein [Homo sapiens]            48   1e-04 
gi|31874060|emb|CAD97946.1|  hypothetical protein [Homo sapi...    48   1e-04 
gi|37181949|gb|AAQ88778.1|  KFQG729 [Homo sapiens]                 48   1e-04 
gi|21757162|dbj|BAC05041.1|  unnamed protein product [Homo s...    47   2e-04 
gi|3077806|dbj|BAA25794.1|  loricrin [Homo sapiens]                47   2e-04 
gi|47132620|ref|NP_000414.2|  keratin 2a [Homo sapiens]            47   2e-04 
gi|190406|gb|AAA36487.1|  profilaggrin                             47   2e-04 
gi|181402|gb|AAC83410.1|  epidermal cytokeratin 2 [Homo sapi...    47   2e-04 
gi|190396|gb|AAA63244.1|  profilaggrin                             47   2e-04 
gi|631466|pir||A53767  mucin MUC5B, tracheobronchial - human...    47   3e-04 
gi|7440064|pir||G02127  fus-like protein - human (fragment) ...    46   4e-04 
gi|223918|prf||1004351A  fibrinogen alphaA                         46   5e-04 
gi|34536377|dbj|BAC87623.1|  unnamed protein product [Homo s...    45   9e-04 
gi|34482047|ref|NP_004635.2|  adaptor-related protein comple...    44   0.001 
gi|54035054|gb|AAH35311.1|  Dermokine [Homo sapiens] >gi|335...    44   0.001 
gi|58036935|emb|CAH18704.2|  hypothetical protein [Homo sapi...    44   0.001 
gi|51472794|ref|XP_370934.3|  PREDICTED: similar to CG15828-...    44   0.001 
gi|51471096|ref|XP_296117.4|  PREDICTED: similar to Heteroge...    44   0.001 
gi|1019902|gb|AAC50219.1|  beta-NAP >gi|1583571|prf||2121258...    44   0.001 
gi|51473184|ref|XP_064152.6|  PREDICTED: sarcalumenin [Homo ...    44   0.002 
gi|190404|gb|AAA63248.1|  profilaggrin                             44   0.002 
gi|346312|pir||A45135  profilaggrin - human (fragment) >gi|5...    44   0.002 
gi|106019|pir||A32947  filaggrin precursor - human (fragment...    44   0.002 
gi|57208868|emb|CAI41110.1|  nucleoporin 214kDa [Homo sapien...    43   0.003 
gi|7710983|emb|CAB90290.1|  insulin receptor substrate 4 [Ho...    43   0.004 
gi|4210363|emb|CAA50559.1|  FUS gycline rich protein [Homo s...    43   0.004 
gi|30583101|gb|AAP35795.1|  fusion, derived from t(12;16) ma...    43   0.004 
gi|547749|sp|P13645|K1CJ_HUMAN  Keratin, type I cytoskeletal...    42   0.006 
gi|71528|pir||KRHU0  keratin 10, type I, cytoskeletal - huma...    42   0.006 
gi|244509|gb|AAB21315.1|  keratin 10 V2 subdomain 142 amino ...    42   0.006 
gi|19913512|gb|AAH26062.1|  Fusion (involved in t(12;16) in ...    42   0.007 
gi|29736952|ref|XP_290401.1|  PREDICTED: hypothetical protei...    42   0.009 
gi|4210364|emb|CAA50558.1|  FUS-CHOP protein fusion [Homo sa...    42   0.009 
gi|55956899|ref|NP_000217.2|  keratin 9 [Homo sapiens]             41   0.012 
gi|435476|emb|CAA82315.1|  cytokeratin 9 [Homo sapiens]            41   0.012 
gi|545257|gb|AAC60619.1|  cytokeratin 9; CK 9 [Homo sapiens]...    41   0.012 
gi|12643948|sp|Q9Y2N3|P121_HUMAN  Nuclear envelope pore memb...    41   0.012 
gi|182424|gb|AAA52426.1|  alpha-fibrinogen precursor               41   0.012 
gi|51466314|ref|XP_499323.1|  PREDICTED: similar to Nuclear ...    41   0.016 
gi|71823|pir||FGHUA  fibrinogen alpha chain precursor, short...    41   0.016 
gi|40788304|dbj|BAA31593.2|  KIAA0618 protein [Homo sapiens]       41   0.016 
gi|4503689|ref|NP_000499.1|  fibrinogen, alpha chain isoform...    41   0.016 
gi|13591823|gb|AAK31372.1|  fibrinogen alpha chain prepropro...    41   0.016 
gi|2136324|pir||I38488  trophinin - human                          40   0.021 
gi|7529568|emb|CAB86651.1|  trophinin [Homo sapiens] >gi|173...    40   0.021 
gi|33304374|gb|AAA79334.2|  trophinin [Homo sapiens]               40   0.021 
gi|58257678|dbj|BAA83066.3|  KIAA1114 protein [Homo sapiens]       40   0.021 
gi|26051278|ref|NP_742017.1|  nuclear pore membrane protein ...    40   0.028 
gi|37182908|gb|AAQ89254.1|  MATN2 [Homo sapiens]                   40   0.028 
gi|51470788|ref|XP_495860.1|  PREDICTED: apomucin [Homo sapi...    40   0.028 
gi|34327775|gb|AAQ63629.1|  heterogeneous nuclear ribonucleo...    40   0.036 
gi|1709063|sp|Q10571|MN1_HUMAN  Probable tumor suppressor pr...    40   0.036 
gi|14043070|ref|NP_112420.1|  heterogeneous nuclear ribonucl...    39   0.061 
gi|51873980|gb|AAH80591.1|  HNRPA3 protein [Homo sapiens]          39   0.061 
gi|10434013|dbj|BAB14097.1|  unnamed protein product [Homo s...    39   0.061 
gi|47077184|dbj|BAD18513.1|  unnamed protein product [Homo s...    39   0.061 
gi|32879987|gb|AAP88824.1|  dishevelled, dsh homolog 2 (Dros...    39   0.080 
gi|88041|pir||A31994  keratin 10, type I, epidermal - human ...    39   0.080 
gi|56788377|ref|NP_001008564.1|  nucleoporin like 1 isoform ...    39   0.080 
gi|32395928|gb|AAP41817.1|  MUC19 [Homo sapiens]                   39   0.080 
gi|244507|gb|AAB21313.1|  keratin 10 V2 subdomain 117 amino ...    39   0.080 
gi|133254|sp|P09651|ROA1_HUMAN  Heterogeneous nuclear ribonu...    39   0.080 
gi|40354192|ref|NP_000412.2|  keratin 10 [Homo sapiens] >gi|...    38   0.10  
gi|55962039|emb|CAI18323.1|  corneodesmosin [Homo sapiens]         38   0.14  
gi|55956910|ref|NP_002421.3|  meningioma  1 [Homo sapiens] >...    38   0.14  
gi|7705545|ref|NP_056932.1|  cytokeratin 2 [Homo sapiens] >g...    38   0.14  
gi|4501991|ref|NP_001126.1|  aggrecan 1 isoform 1 precursor ...    38   0.14  
gi|6995994|ref|NP_037359.1|  aggrecan 1 isoform 2 precursor ...    38   0.14  
gi|55733689|emb|CAA57693.2|  MN1 protein [Homo sapiens]            38   0.14  
gi|31074629|emb|CAD91891.1|  keratin 2p [Homo sapiens]             38   0.14  
gi|25756916|pir||A39086  aggrecan precursor, cartilage long ...    38   0.14  
gi|11360063|pir||T46488  hypothetical protein DKFZp434J065.1...    38   0.14  
gi|58218973|ref|NP_001010850.1|  fusion (involved in t(12;16...    38   0.14  
gi|129886|sp|P16112|PGCA_HUMAN  Aggrecan core protein precur...    38   0.14  
gi|7428712|pir||KRHU2  keratin 1, type II, cytoskeletal - human    37   0.18  
gi|4507353|ref|NP_003478.1|  TBP-associated factor 15 isofor...    37   0.18  
gi|14192943|ref|NP_115822.1|  MEGF10 protein [Homo sapiens] ...    37   0.18  
gi|38014361|gb|AAH01518.2|  POM121 protein [Homo sapiens]          37   0.18  
gi|14714613|gb|AAH10444.1|  MATN2 protein [Homo sapiens]           37   0.18  
gi|18044366|gb|AAH20198.1|  MEGF10 protein [Homo sapiens]          37   0.18  
gi|32425428|gb|AAH16394.1|  MATN2 protein [Homo sapiens]           37   0.18  
gi|21327701|ref|NP_631961.1|  TBP-associated factor 15 isofo...    37   0.18  
gi|55662302|emb|CAH72941.1|  novel protein similar to mouse ...    37   0.18  
gi|51458803|ref|XP_371320.2|  PREDICTED: FLJ00193 protein [H...    37   0.18  
gi|28279785|gb|AAH46099.1|  TAF15 protein [Homo sapiens]           37   0.18  
gi|13518039|ref|NP_085072.1|  matrilin 2 precursor [Homo sap...    37   0.18  
gi|13518037|ref|NP_002371.2|  matrilin 2 precursor [Homo sap...    37   0.18  
gi|21739491|emb|CAD38787.1|  hypothetical protein [Homo sapi...    37   0.18  
gi|21307718|gb|AAK62026.1|  GW182 autoantigen [Homo sapiens]...    37   0.23  
gi|186629|gb|AAA59199.1|  keratin 10                               37   0.23  
gi|21702733|ref|NP_065898.1|  trinucleotide repeat containin...    37   0.23  
gi|55741878|ref|NP_065798.1|  zinc finger protein 608 [Homo ...    37   0.23  
gi|50660400|gb|AAT80901.1|  striated muscle preferentially e...    37   0.23  
gi|27894378|ref|NP_444507.1|  chloride intracellular channel...    37   0.23  
gi|25990944|gb|AAN76730.1|  chloride channel form B [Homo sa...    37   0.23  
gi|52545626|emb|CAB70853.2|  hypothetical protein [Homo sapi...    37   0.23  
gi|51476585|emb|CAH18275.1|  hypothetical protein [Homo sapi...    37   0.23  
gi|8699046|gb|AAF78570.1|  corneodesmosin [Homo sapiens] >gi...    37   0.23  
gi|7242949|dbj|BAA92535.1|  KIAA1297 protein [Homo sapiens]        37   0.23  
gi|20521822|dbj|BAA86595.2|  KIAA1281 protein [Homo sapiens]       37   0.23  
gi|2765322|emb|CAA73867.1|  RB18A protein [Homo sapiens]           37   0.30  
gi|55958451|emb|CAI12730.1|  OTTHUMP00000018488 [Homo sapiens]     37   0.30  
gi|51493076|ref|XP_370728.2|  PREDICTED: similar to heteroge...    37   0.30  
gi|51468696|ref|XP_372445.2|  PREDICTED: similar to VsaA -li...    37   0.30  
gi|28559039|ref|NP_004765.2|  peroxisome proliferator-activa...    37   0.30  
gi|3319290|gb|AAC39854.1|  thyroid hormone receptor-associat...    37   0.30  
gi|28558772|sp|Q15648|PPRB_HUMAN  Peroxisome proliferator-ac...    37   0.30  
gi|9789555|gb|AAF98352.1|  vitamin D receptor-interacting pr...    37   0.30  
gi|7959181|dbj|BAA95984.1|  KIAA1460 protein [Homo sapiens]        37   0.30  
gi|386854|gb|AAA36153.1|  type II keratin subunit protein          36   0.40  
gi|9663124|emb|CAC01124.1|  ILF3 [Homo sapiens]                    36   0.40  
gi|8017378|emb|CAB92132.1|  hypothetical protein [Homo sapiens]    36   0.52  
gi|13124888|ref|NP_056322.2|  epidermal growth factor-like p...    36   0.52  
gi|37181791|gb|AAQ88699.1|  EGFL6 [Homo sapiens]                   36   0.52  
gi|22761159|dbj|BAC11477.1|  unnamed protein product [Homo s...    36   0.52  
gi|57209317|emb|CAI40809.1|  proprotein convertase subtilisi...    36   0.52  
gi|57209230|emb|CAI40674.1|  OTTHUMP00000063526 [Homo sapiens]     36   0.52  
gi|11935049|gb|AAG41947.1|  keratin 1 [Homo sapiens] >gi|173...    36   0.52  
gi|9055270|ref|NP_061027.1|  low density lipoprotein-related...    36   0.52  
gi|6752658|gb|AAF27812.1|  epidermal growth factor repeat co...    36   0.52  
gi|1346343|sp|P04264|K2C1_HUMAN  Keratin, type II cytoskelet...    36   0.52  
gi|15079614|gb|AAH11625.1|  Zinc finger protein 503 [Homo sa...    35   0.68  
gi|30582787|gb|AAP35620.1|  ring finger protein 10 [Homo sap...    35   0.68  
gi|225922|prf||1403304A  von Willebrand factor                     35   0.68  
gi|45594508|ref|NP_996669.1|  similar to Hypothetical protei...    35   0.68  
gi|24234750|ref|NP_036350.2|  interleukin enhancer binding f...    35   0.68  
gi|21619487|gb|AAH31596.1|  Ring finger protein 10 [Homo sap...    35   0.68  
gi|5762315|gb|AAD51099.1|  nuclear factor associated with ds...    35   0.68  
gi|11125762|gb|AAC51260.2|  matrilin-2 precursor [Homo sapie...    35   0.68  
gi|1200090|emb|CAA29985.1|  von Willebrand factor [Homo sapi...    35   0.68  
gi|9081981|gb|AAF82685.1|  dsRNA binding protein NFAR-2/MPP4...    35   0.68  
gi|33413425|ref|NP_061869.2|  trinucleotide repeat containin...    35   0.89  
gi|56789238|gb|AAH88362.1|  DEAD (Asp-Glu-Ala-Asp) box polyp...    35   0.89  
gi|17318572|ref|NP_476429.1|  keratin 3 [Homo sapiens] >gi|8...    35   0.89  
gi|52545795|emb|CAH56330.1|  hypothetical protein [Homo sapi...    35   0.89  
gi|12746296|gb|AAK07425.1|  110 kDa NFAR protein [Homo sapiens]    35   0.89  
gi|34041|emb|CAA28991.1|  keratin type II (AA1-215) [Homo sa...    35   0.89  
gi|57015418|sp|Q9NZR2|LR1B_HUMAN  Low-density lipoprotein re...    35   0.89  
gi|9438227|gb|AAF86585.1|  DEAD box RNA helicase [Homo sapiens]    35   0.89  
gi|20521948|dbj|BAB13408.2|  KIAA1582 protein [Homo sapiens]       35   0.89  
gi|18676590|dbj|BAB84947.1|  FLJ00193 protein [Homo sapiens]       35   0.89  
gi|4503667|ref|NP_001990.1|  fibrillin 2 (congenital contrac...    35   1.2   
gi|10257390|gb|AAG15395.1|  serine protease TADG15 [Homo sap...    35   1.2   
gi|34782939|gb|AAH05826.2|  ST14 protein [Homo sapiens]            35   1.2   
gi|17390323|gb|AAH18146.1|  ST14 protein [Homo sapiens]            35   1.2   
gi|13938287|gb|AAH07271.1|  Heterogeneous nuclear ribonucleo...    35   1.2   
gi|57162675|emb|CAI39902.1|  nucleoporin like 1 [Homo sapiens]     35   1.2   
gi|41150277|ref|XP_370982.1|  PREDICTED: similar to Heteroge...    35   1.2   
gi|9714272|emb|CAC01407.1|  double stranded RNA binding nucl...    35   1.2   
gi|11415040|ref|NP_068813.1|  matriptase [Homo sapiens] >gi|...    35   1.2   
gi|627438|pir||A54105  fibrillin-2 precursor - human               35   1.2   
gi|10179932|gb|AAG13949.1|  serine protease SNC19 [Homo sapi...    35   1.2   
gi|12249015|dbj|BAB20376.1|  prostamin [Homo sapiens]              35   1.2   
gi|45827750|ref|NP_996672.1|  Fraser syndrome 1 isoform 2 [H...    34   1.5   
gi|45827744|ref|NP_079350.3|  Fraser syndrome 1 isoform 1 [H...    34   1.5   
gi|54312050|ref|NP_001400.1|  EGF-like-domain, multiple 3 [H...    34   1.5   
gi|55960625|emb|CAI14334.1|  EGF-like-domain, multiple 3 [Ho...    34   1.5   
gi|7021194|dbj|BAA91402.1|  unnamed protein product [Homo sa...    34   1.5   
gi|29420380|emb|CAD54734.1|  extracellular matrix protein [H...    34   1.5   
gi|1911429|gb|AAB50657.1|  A0=heterogeneous nuclear ribonucl...    34   1.5   
gi|46395624|sp|O75095|EFL3_HUMAN  Multiple EGF-like-domain p...    34   1.5   
gi|3220177|gb|AAC23559.1|  epidermal filaggrin [Homo sapiens]      34   1.5   
gi|18088164|gb|AAH21165.1|  ZNF503 protein [Homo sapiens] >g...    34   2.0   
gi|24430141|ref|NP_000129.2|  fibrillin 1 [Homo sapiens]           34   2.0   
gi|57209284|emb|CAI41712.1|  ring finger protein 12 [Homo sa...    34   2.0   
gi|21739669|emb|CAD38875.1|  hypothetical protein [Homo sapi...    34   2.0   
gi|1335064|emb|CAA45118.1|  fibrillin [Homo sapiens]               34   2.0   
gi|455958|gb|AAB29419.1|  fibrillin [human, Marfan syndrome ...    34   2.0   
gi|14042323|dbj|BAB55198.1|  unnamed protein product [Homo s...    34   2.0   
gi|7022528|dbj|BAA91632.1|  unnamed protein product [Homo sa...    34   2.0   
gi|10944884|emb|CAC14228.1|  RING zinc finger LIM domain bin...    34   2.0   
gi|5360113|gb|AAD42875.1|  putative ring zinc finger protein...    34   2.0   
gi|7459676|pir||A47221  fibrillin 1 precursor - human (fragm...    34   2.0   
gi|1945053|gb|AAC51519.1|  intestinal mucin [Homo sapiens]         34   2.0   
gi|8699040|gb|AAF78567.1|  corneodesmosin [Homo sapiens]           34   2.0   
gi|46559358|dbj|BAD16739.1|  fibrillin 1 [Homo sapiens]            34   2.0   
gi|13124522|sp|Q9NVW2|RNF12_HUMAN  RING finger protein 12 (L...    34   2.0   
gi|227918|prf||1713408A  fibrillin                                 34   2.0   
gi|51471037|ref|XP_495921.1|  PREDICTED: mucin 19 [Homo sapi...    33   2.6   
gi|56207228|emb|CAI18567.1|  protein phosphatase 1, regulato...    33   2.6   
gi|42476169|ref|NP_061961.2|  hypothetical protein F23149_1 ...    33   2.6   
gi|10434911|dbj|BAB14420.1|  unnamed protein product [Homo s...    33   2.6   
gi|4758948|ref|NP_004566.1|  POU domain, class 4, transcript...    33   2.6   
gi|45829834|gb|AAH68200.1|  KIAA1102 protein [Homo sapiens]        33   2.6   
gi|52630326|ref|NP_001005273.1|  chromodomain helicase DNA b...    33   2.6   
gi|52630324|ref|NP_001005271.1|  chromodomain helicase DNA b...    33   2.6   
gi|4758410|ref|NP_004851.1|  fragile X mental retardation sy...    33   2.6   
gi|7023594|dbj|BAA92020.1|  unnamed protein product [Homo sa...    33   2.6   
gi|32484979|ref|NP_003655.3|  adaptor-related protein comple...    33   2.6   
gi|14192941|ref|NP_115821.1|  MEGF11 protein [Homo sapiens] ...    33   2.6   
gi|23512245|gb|AAH38444.1|  Adaptor-related protein complex ...    33   2.6   
gi|10732634|gb|AAG22483.1|  unknown [Homo sapiens]                 33   2.6   
gi|7512912|pir||T17343  hypothetical protein DKFZp586K0524.1...    33   2.6   
gi|11359857|pir||T50652  AP-3 complex beta3A chain [imported...    33   2.6   
gi|3287674|gb|AAC25503.1|  F23149_1 [Homo sapiens]                 33   2.6   
gi|47077813|dbj|BAD18778.1|  unnamed protein product [Homo s...    33   2.6   
gi|21739946|emb|CAD38994.1|  hypothetical protein [Homo sapi...    33   2.6   
gi|20071599|gb|AAH26967.1|  ZDHHC5 protein [Homo sapiens]          33   2.6   
gi|12698041|dbj|BAB21839.1|  KIAA1748 protein [Homo sapiens]       33   2.6   
gi|55663572|emb|CAH70367.1|  Zic family member 2 (odd-paired...    33   3.4   
gi|37610|emb|CAA27874.1|  unnamed protein product [Homo sapi...    33   3.4   
gi|55930978|gb|AAH52296.1|  Heterogeneous nuclear ribonucleo...    33   3.4   
gi|13491168|ref|NP_056132.1|  pumilio homolog 2 [Homo sapien...    33   3.4   
gi|31979171|gb|AAP68819.1|  replicative senescence downregul...    33   3.4   
gi|51476146|emb|CAH18063.1|  hypothetical protein [Homo sapi...    33   3.4   
gi|31873943|emb|CAD97899.1|  hypothetical protein [Homo sapi...    33   3.4   
gi|52545889|emb|CAD39044.2|  hypothetical protein [Homo sapi...    33   3.4   
gi|34364952|emb|CAE46023.1|  hypothetical protein [Homo sapi...    33   3.4   
gi|8922079|ref|NP_061160.1|  apolipoprotein B48 receptor [Ho...    33   3.4   
gi|16550571|dbj|BAB71006.1|  unnamed protein product [Homo s...    33   3.4   
gi|7020236|dbj|BAA91044.1|  unnamed protein product [Homo sa...    33   3.4   
gi|47939618|gb|AAH71945.1|  Heterogeneous nuclear ribonucleo...    33   3.4   
gi|8699630|gb|AAF78765.1|  placenta apolipoprotein B48 recep...    33   3.4   
gi|29421196|dbj|BAA96000.2|  KIAA1476 protein [Homo sapiens]       33   3.4   
gi|13436308|gb|AAH04945.1|  Unknown (protein for IMAGE:36153...    33   3.4   
gi|4028592|gb|AAC96325.1|  ZIC2 protein [Homo sapiens]             33   3.4   
gi|8699030|gb|AAF78562.1|  corneodesmosin [Homo sapiens]           33   3.4   
gi|8699028|gb|AAF78561.1|  corneodesmosin [Homo sapiens]           33   3.4   
gi|87650|pir||S02061  heterogeneous ribonuclear particle pro...    33   3.4   
gi|12407623|gb|AAG53596.1|  differentially expressed nucleol...    33   3.4   
gi|125098|sp|P12035|K2C3_HUMAN  Keratin, type II cytoskeleta...    33   3.4   
gi|41688714|sp|Q8TB72|PUM2_HUMAN  Pumilio homolog 2 (Pumilio2)     33   3.4   
gi|21706515|gb|AAH34052.1|  MGC15476 protein [Homo sapiens]        33   4.4   
gi|29839261|sp|O94988|F131_HUMAN  Protein FAM13A1                  33   4.4   
gi|39644750|gb|AAH06397.2|  RBM15 protein [Homo sapiens] >gi...    33   4.4   
gi|42760012|emb|CAF31522.1|  keratin 3 [Homo sapiens]              33   4.4   
gi|56119110|ref|NP_055698.2|  family with sequence similarit...    33   4.4   
gi|57997044|emb|CAB56014.2|  hypothetical protein [Homo sapi...    33   4.4   
gi|56206301|emb|CAI19077.1|  RNA binding motif protein 15 [H...    33   4.4   
gi|28958098|gb|AAH47479.1|  RBM15 protein [Homo sapiens]           33   4.4   
gi|20805887|gb|AAM28881.1|  basic helix-loop-helix protein 5...    33   4.4   
gi|34535884|dbj|BAC87462.1|  unnamed protein product [Homo s...    33   4.4   
gi|34533713|dbj|BAC86783.1|  unnamed protein product [Homo s...    33   4.4   
gi|14041648|emb|CAC38829.1|  OTT-MAL [Homo sapiens]                33   4.4   
gi|14041646|emb|CAC38828.1|  OTT-MAL [Homo sapiens]                33   4.4   
gi|14140100|emb|CAC38862.1|  one twenty two protein [Homo sa...    33   4.4   
gi|14140099|emb|CAC38861.1|  one twenty two protein [Homo sa...    33   4.4   
gi|58257670|dbj|BAA74937.3|  KIAA0914 protein [Homo sapiens]       33   4.4   
gi|51476641|emb|CAH18299.1|  hypothetical protein [Homo sapi...    33   4.4   
gi|7512796|pir||T17324  hypothetical protein DKFZp564P2063.1...    33   4.4   
gi|7512423|pir||JE0291  FB19 protein - human >gi|2117159|emb...    33   4.4   
gi|3253165|gb|AAC39791.1|  SR protein [Homo sapiens]               33   4.4   
gi|56269621|gb|AAH86875.1|  FAM13A1 protein [Homo sapiens]         33   4.4   
gi|55958434|emb|CAI14551.1|  integrin, beta-like 1 (with EGF...    32   5.8   
gi|23238166|gb|AAN16024.1|  ITGBL1 [Homo sapiens] >gi|559584...    32   5.8   
gi|4826766|ref|NP_004958.1|  integrin-binding sialoprotein p...    32   5.8   
gi|51095016|gb|EAL24260.1|  nucleoporin like 2 [Homo sapiens...    32   5.8   
gi|26787970|ref|NP_001255.2|  corneodesmosin precursor [Homo...    32   5.8   
gi|55961420|emb|CAI17719.1|  corneodesmosin [Homo sapiens] >...    32   5.8   
gi|3182951|sp|Q15517|CDSN_HUMAN  Corneodesmosin precursor (S...    32   5.8   
gi|2921270|gb|AAC24196.1|  corneodesmosin [Homo sapiens]           32   5.8   
gi|21619292|gb|AAH31993.1|  CDSN protein [Homo sapiens]            32   5.8   
gi|16306757|gb|AAH01566.1|  TSPYL2 protein [Homo sapiens]          32   5.8   
gi|18999495|gb|AAH24270.1|  TSPY-like 2 [Homo sapiens] >gi|5...    32   5.8   
gi|56206477|emb|CAI18479.1|  corneodesmosin [Homo sapiens]         32   5.8   
gi|55961066|emb|CAI15375.1|  novel protein [Homo sapiens]          32   5.8   
gi|51475785|ref|XP_371878.3|  PREDICTED: hypothetical protei...    32   5.8   
gi|51466066|ref|XP_374405.3|  PREDICTED: similar to Neurogen...    32   5.8   
gi|6010135|emb|CAB57271.1|  corneodesmosin [Homo sapiens]          32   5.8   
gi|8176538|gb|AAB32714.2|  FUS-CHOP fusion protein [Homo sap...    32   5.8   
gi|27544426|dbj|BAC54948.1|  modified desmosin expressed in ...    32   5.8   
gi|9937327|gb|AAG02419.1|  corneodesmosin [Homo sapiens] >gi...    32   5.8   
gi|8699038|gb|AAF78566.1|  corneodesmosin [Homo sapiens] >gi...    32   5.8   
gi|8699026|gb|AAF78560.1|  corneodesmosin [Homo sapiens]           32   5.8   
gi|8699024|gb|AAF78559.1|  corneodesmosin [Homo sapiens]           32   5.8   
gi|539576|pir||A48679  differentiated keratinocyte S protein...    32   5.8   
gi|47077657|dbj|BAD18709.1|  FLJ00267 protein [Homo sapiens]       32   5.8   
gi|25005087|gb|AAN70995.1|  corneodesmosin [Homo sapiens]          32   5.8   
gi|22859187|emb|CAD45447.1|  putative RIN zinc finger protei...    32   5.8   
gi|3970876|dbj|BAA34802.1|  HRIHFB2216 [Homo sapiens]              32   5.8   
gi|2570152|dbj|BAA22994.1|  osteoblast specific cysteine-ric...    32   5.8   
gi|51105830|gb|EAL24430.1|  zinc finger protein 282 [Homo sa...    32   7.5   
gi|50428935|ref|NP_060644.4|  BPY2 interacting protein 1 [Ho...    32   7.5   
gi|37674396|gb|AAC60381.2|  unknown [Homo sapiens] >gi|51095...    32   7.5   
gi|11497006|ref|NP_068604.1|  a disintegrin and metalloprote...    32   7.5   
gi|244508|gb|AAB21314.1|  keratin 10 V2 subdomain 128 amino ...    32   7.5   
gi|1857673|gb|AAB51586.1|  TNF-alpha converting enzyme [Homo...    32   7.5   
gi|13938400|gb|AAH07338.1|  H41 protein [Homo sapiens]             32   7.5   
gi|33243951|gb|AAH55287.1|  ZNF282 protein [Homo sapiens]          32   7.5   
gi|22002953|emb|CAD29574.1|  VCY2 interacting protein-1 [Hom...    32   7.5   
gi|8923710|ref|NP_060018.1|  hypothetical protein H41 [Homo ...    32   7.5   
gi|32879977|gb|AAP88819.1|  fragile X mental retardation, au...    32   7.5   
gi|15431285|ref|NP_076418.2|  zinc finger and BTB domain con...    32   7.5   
gi|10434894|dbj|BAB14415.1|  unnamed protein product [Homo s...    32   7.5   
gi|14042429|dbj|BAB55242.1|  unnamed protein product [Homo s...    32   7.5   
gi|7022844|dbj|BAA91743.1|  unnamed protein product [Homo sa...    32   7.5   
gi|51467069|ref|XP_498297.1|  PREDICTED: similar to nucleolu...    32   7.5   
gi|51464632|ref|XP_373106.2|  PREDICTED: similar to Tb-291 m...    32   7.5   
gi|51464112|ref|XP_087386.6|  PREDICTED: HEG homolog [Homo s...    32   7.5   
gi|13940223|emb|CAC37946.1|  doublesex-mab-3 (DM) domain [Ho...    32   7.5   
gi|51873972|gb|AAH80547.1|  BPY2 interacting protein 1 [Homo...    32   7.5   
gi|34327974|dbj|BAA86551.2|  KIAA1237 protein [Homo sapiens]       32   7.5   
gi|27693942|gb|AAH41704.1|  Similar to expressed sequence AI...    32   7.5   
gi|30354026|gb|AAH51907.1|  Fragile X mental retardation syn...    32   7.5   
gi|30268349|emb|CAD89974.1|  hypothetical protein [Homo sapi...    32   7.5   
gi|45595641|gb|AAH67115.1|  BPY2IP1 protein [Homo sapiens]         32   7.5   
gi|39644758|gb|AAH06358.2|  BPY2IP1 protein [Homo sapiens]         32   7.5   
gi|13938255|gb|AAH07253.1|  BPY2IP1 protein [Homo sapiens]         32   7.5   
gi|38197049|gb|AAH08806.2|  BPY2IP1 protein [Homo sapiens]         32   7.5   
gi|12643382|sp|Q9UDV7|ZN282_HUMAN  Zinc finger protein 282 (...    32   7.5   
gi|21739763|emb|CAD38911.1|  hypothetical protein [Homo sapi...    32   7.5   
gi|2789430|dbj|BAA24380.1|  repressor protein [Homo sapiens]       32   7.5   
gi|21104446|dbj|BAB93493.1|  hypothetical protein [Homo sapi...    32   7.5   
gi|51173722|ref|NP_004625.2|  bromodomain and PHD finger-con...    32   9.8   
gi|47716512|ref|NP_115622.2|  ring finger and KH domain cont...    32   9.8   
gi|57209220|emb|CAI41540.1|  Alport syndrome, mental retarda...    32   9.8   
gi|1705500|sp|P55201|BRPF1_HUMAN  Peregrin (Bromodomain and ...    32   9.8   
gi|38045910|ref|NP_937762.1|  laminin alpha 3 subunit isofor...    32   9.8   
gi|33620747|ref|NP_057216.2|  myelin gene expression factor ...    32   9.8   
gi|34452239|gb|AAQ72571.1|  laminin alpha 3 splice variant b...    32   9.8   
gi|28569546|gb|AAO43677.1|  rac GTPase activating protein; G...    32   9.8   
gi|56549645|ref|NP_624358.2|  nucleoporin 98kD isoform 4 [Ho...    32   9.8   
gi|21264369|ref|NP_624357.1|  nucleoporin 98kD isoform 2 [Ho...    32   9.8   
gi|18490660|gb|AAH22443.1|  ZCCHC10 protein [Homo sapiens]         32   9.8   
gi|51173720|ref|NP_001003694.1|  bromodomain and PHD finger-...    32   9.8   
gi|56204139|emb|CAI23011.1|  DMRT-like family A2 [Homo sapiens]    32   9.8   
gi|51471484|ref|XP_377305.2|  PREDICTED: similar to Hypothet...    32   9.8   
gi|6063689|emb|CAB58123.1|  AMMECR1 [Homo sapiens]                 32   9.8   
gi|7019971|dbj|BAA90946.1|  unnamed protein product [Homo sa...    32   9.8   
gi|34532284|dbj|BAC86373.1|  unnamed protein product [Homo s...    32   9.8   
gi|26996545|gb|AAH41136.1|  Nucleoporin 98kD, isoform 2 [Hom...    32   9.8   
gi|21264365|ref|NP_057404.2|  nucleoporin 98kD isoform 1 [Ho...    32   9.8   
gi|18032249|gb|AAL56659.1|  NUP196 nucleoporin [Homo sapiens]      32   9.8   
gi|19584408|emb|CAD28495.1|  hypothetical protein [Homo sapi...    32   9.8   
gi|1924948|emb|CAA71821.1|  twist [Homo sapiens] >gi|7513409...    32   9.8   
gi|24899182|dbj|BAC23105.1|  KIAA2009 protein [Homo sapiens]       32   9.8   
gi|4545101|gb|AAD22396.1|  Nup98-Nup96 precursor splice vari...    32   9.8   
gi|4545099|gb|AAD22395.1|  Nup98-Nup96 precursor [Homo sapiens]    32   9.8   
gi|543063|pir||JC2069  zinc-finger protein, BR140 - human          32   9.8   
gi|2627429|gb|AAC51867.1|  laminin alpha 3b chain [Homo sapi...    32   9.8   
gi|3298562|gb|AAC39923.1|  zinc-finger helicase [Homo sapiens]     32   9.8   
gi|46020022|dbj|BAD13428.1|  laminin alpha 3b chain [Homo sa...    32   9.8   
gi|21739151|emb|CAB66712.2|  hypothetical protein [Homo sapi...    32   9.8   
gi|38511526|gb|AAH60813.1|  AMMECR1 protein [Homo sapiens]         32   9.8   
gi|7243063|dbj|BAA92579.1|  KIAA1341 protein [Homo sapiens]        32   9.8   
gi|21698920|dbj|BAA34432.2|  KIAA0712 protein [Homo sapiens]       32   9.8   


Alignments

>gi|51471105|ref|XP_497341.1|   PREDICTED: similar to submaxillary apomucin [Homo sapiens]
          Length = 7202

 Score =  735 bits (1898), Expect = 0.0
 Identities = 414/607 (68%), Positives = 427/607 (70%), Gaps = 148/607 (24%)

Query: 1   MKLILWYLVVALWCFFKDGK--IAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETED 58
           MKLILWYLVVALWCFFKD +  +   +SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETED
Sbjct: 1   MKLILWYLVVALWCFFKDVEALLYRQKSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETED 60

Query: 59  KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG 118
           KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG
Sbjct: 61  KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG 120

Query: 119 SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRE---------------- 162
           SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRE                
Sbjct: 121 SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPADS 180

Query: 163 ---RWDAGNSRSEDS----------------------------------------PAVGT 179
              R+ AG S S  S                                         AVGT
Sbjct: 181 TNTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGT 240

Query: 180 GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSE 239
           GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSE
Sbjct: 241 GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSE 300

Query: 240 -------------------------NQFVGGGSLNSIS---------------------- 252
                                    N+  G G   S+S                      
Sbjct: 301 NQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVGMLESL 360

Query: 253 -------------NLWDSGQEGFGINEIGGNGM-------SGSVSAEAGF-------KGF 285
                        +   SG   FG NE+  NG+       S  ++   GF       KGF
Sbjct: 361 EFGLGGKKVGAGFDFKYSGSRKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKGF 420

Query: 286 G-------------SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDF 332
           G             SD S +VEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDF
Sbjct: 421 GTSGSGWNEQSSSKSDVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDF 480

Query: 333 DGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPG 392
           DGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPG
Sbjct: 481 DGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPG 540

Query: 393 SDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSE 452
           SDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSE
Sbjct: 541 SDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSE 600

Query: 453 TNAIIGQ 459
           TNAIIG+
Sbjct: 601 TNAIIGE 607



 Score =  652 bits (1683), Expect = 0.0
 Identities = 304/305 (99%), Positives = 305/305 (100%)

Query: 602  DKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDF 661
            DKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDF
Sbjct: 1025 DKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDF 1084

Query: 662  MSSQNILEKTSQAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPI 721
            MSSQNILEKTSQAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPI
Sbjct: 1085 MSSQNILEKTSQAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPI 1144

Query: 722  VNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVF 781
            VNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVF
Sbjct: 1145 VNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVF 1204

Query: 782  KYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVM 841
            KYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVM
Sbjct: 1205 KYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVM 1264

Query: 842  QPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNI 901
            QPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNI
Sbjct: 1265 QPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNI 1324

Query: 902  PVFDD 906
            PVFD+
Sbjct: 1325 PVFDE 1329



 Score =  549 bits (1415), Expect = e-155
 Identities = 270/384 (70%), Positives = 288/384 (75%), Gaps = 38/384 (9%)

Query: 799  DRSCDVEDVPV--------DGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID 850
            +R+C   ++PV         GC CP+ M +N++G CV  + C C         G +  + 
Sbjct: 1316 NRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG 1375

Query: 851  DNKCVCRDGI---------LLCQIPIDLTLQNCSGGAEYVD-----------CSDPKAQR 890
             N+C C  G           +C I  +  ++   G +   D           C       
Sbjct: 1376 CNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTF 1435

Query: 891  RT----------NRTCSTRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG 940
            R             TCS + I  F DQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG
Sbjct: 1436 RILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG 1495

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL
Sbjct: 1496 LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1555

Query: 1001 EFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC 1060
            EFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC
Sbjct: 1556 EFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC 1615

Query: 1061 IEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYE 1120
            IEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYE
Sbjct: 1616 IEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYE 1675

Query: 1121 PCGTVTAKTCKDQLVGQKFSSLLE 1144
            PCGTVTAKTCKDQLVGQKFSSLLE
Sbjct: 1676 PCGTVTAKTCKDQLVGQKFSSLLE 1699



 Score =  338 bits (868), Expect = 3e-92
 Identities = 246/582 (42%), Positives = 299/582 (51%), Gaps = 83/582 (14%)

Query: 66  AGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAED-KSGDSQDAGGSKSEDT 124
           +GS  +E    G   +SSSS G  +  +  F LG    G   D K   S+  GG++  + 
Sbjct: 334 SGSVSAEAGFKGFGSDSSSSVGMLESLE--FGLGGKKVGAGFDFKYSGSRKFGGNELSEN 391

Query: 125 PPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL 184
             G      SSS D  +       +FG  G     S   W+  +S   D       S   
Sbjct: 392 --GIKVTRESSSSDLAENLGFGLEKFGQKGFGTSGSG--WNEQSSSKSDVSGAVEKSWLF 447

Query: 185 KLGAG--KGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQF 242
           + G G  KG A F F  S SN  GD G SSK  +GN            +GD+S R+  + 
Sbjct: 448 EFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGN-----------GVGDSSARNGFEN 496

Query: 243 VGGGSLNSISNLWDSGQEGFGINEIGGNGMS------------GSVSAEAGFKGFGSDSS 290
             G S +S   L  S Q    ++  GGN               GS  +++G   + SDS 
Sbjct: 497 SSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSG 556

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDN--GNSSKDFDGNGV---------GD 339
           S        E G+G + G  EF       ++ G +    + K  + N +         G 
Sbjct: 557 SGGGGKSADELGVGAS-GLNEFGETGLSGSEKGSHIPEATPKYSETNAIIGEISTWSKGA 615

Query: 340 SSARNG----FENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDV 395
             + NG    FE+S   +     I    D   +E+ R        S+ ++   L   +DV
Sbjct: 616 YKSFNGRIFFFESSCPYTFCRHCIESGGD-FNIEIKRNN-----DSEIEKITVLIDNNDV 669

Query: 396 SDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG--SHIPEATPKYSET 453
           S  G       +                  + ++GE  +  S +G  + + +   K S T
Sbjct: 670 SIFGDTILIPYNNK-------------LIHIKKYGEHNVLNSRRGILTLMWDKNNKLSLT 716

Query: 454 --------------NAIIGQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTY 499
                         N+  GQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTY
Sbjct: 717 LHKQYPTCGLCGNFNSTPGQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTY 776

Query: 500 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 559
           FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV
Sbjct: 777 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 836

Query: 560 CGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPE 601
           CGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPE
Sbjct: 837 CGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPE 878



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 111/455 (24%), Positives = 174/455 (38%), Gaps = 68/455 (14%)

Query: 465  IANSK----IPGDCPNAVG-KSYE---VCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMI 516
            + NSK     P DCP + G + Y+   V   G   C  I G++       +   N+ + I
Sbjct: 1344 VRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSW-------SCTQNECQTI 1396

Query: 517  CI---DEYCQTRD-KTSTCD---TYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQH 569
            C    + + +T D K+ + D    YS L   C  +  GTF        ++  +  C E  
Sbjct: 1397 CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN-GTFR-------ILTESVPCCEDG 1448

Query: 570  IYKECGPSNPATCSN--VAPFQDSECV------SGCTCPEDKIQIFNASS-SYLQVETYF 620
            +          TCS   +  FQD   V      +     E K    NA++ S   V  Y 
Sbjct: 1449 L----------TCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYL 1498

Query: 621  HVKLQIQIVPVM----QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFA 676
             +K Q  I+ +     +L V + PN      GLCG+ N   +DDF +  + +   +  F 
Sbjct: 1499 ILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFG 1558

Query: 677  NSWEMMSCPKGNPSSCISIEKEKF----AERHCGILLDSSGPLASCHPIVNPKPYHEECK 732
            NSW+         +     +   +    A R C IL DS+     CH  V+P  YH+ C 
Sbjct: 1559 NSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDST--FRDCHNKVDPSAYHDVCI 1616

Query: 733  KYTCTCENSQDCL--CTILGNYVKACAEKETYIVGWRTGLCEHSCP---SGLVFKYNVKA 787
            +  C C+     L  CT +  Y +AC+     +   +  LC   C    +    +++ + 
Sbjct: 1617 EEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEP 1676

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGC--TCPDA--MYQNNEGNCVLKSQCDCYINDEVMQP 843
            C +      +           ++GC   CPD+      N   CV  S+C C+ ND +   
Sbjct: 1677 CGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAG 1736

Query: 844  GKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGA 878
            G +       C C  G L C +         S GA
Sbjct: 1737 GVIEDNCGRTCYCIAGQLECSVSTTTATTILSTGA 1771



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 50/213 (23%), Positives = 77/213 (36%), Gaps = 42/213 (19%)

Query: 930  NANAYSIHTVGLYLILKFQNGIIVI-WDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 988
            N     I   G + +L  + GI+ + WDKN +LS+ L   +    CGLCGN N     D 
Sbjct: 681  NNKLIHIKKYGEHNVLNSRRGILTLMWDKNNKLSLTLHKQY--PTCGLCGNFNSTPGQDI 738

Query: 989  TTRYSSVASGALEFGNSWKTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRDSTFRDC 1047
                ++            K   +C + V +++  C+         ++ C  +  + F  C
Sbjct: 739  NEHIANS-----------KIPGDCPNAVGKSYEVCED-------GIQHCNKIIGTYFEKC 780

Query: 1048 HNKVDPS-AYHDVCIEEAC-------ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKP 1099
                  S  Y  +CI+E C        CD   +    C        A    G   SWR  
Sbjct: 781  GKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLC--------ASDGPGTFESWRSD 832

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
            +   V C     P +    Y+ CG     TC +
Sbjct: 833  S--DVVCGTQRCPEQ--HIYKECGPSNPATCSN 861



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 71/269 (26%), Positives = 110/269 (40%), Gaps = 41/269 (15%)

Query: 153  TGEDEDKSRERWDAGNSR-SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGIS 211
            TG   + + ER  AG  R S ++PAVG GS+        G+A  G  VS     G TG+S
Sbjct: 1839 TGAASENTSER--AGTPRVSGETPAVGGGST-------PGEAGPGATVS-----GSTGVS 1884

Query: 212  SKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNG 271
            + ++  +  +S+  S S   G T   S     G  S  + S+   SG  G  +    G+ 
Sbjct: 1885 AGSITASPGASATSSESSKSGTTG-PSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGS- 1942

Query: 272  MSGSVSAEAGFKGFGSDSS-SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
                ++A+  F G       +         F  G T+ G       +G N SG  G++  
Sbjct: 1943 -DSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGST-- 1999

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG-GNRKRSSDPDEAGNL 389
              +G+    +SA +G  N++G S       G+ D        TG GN   S  P  +   
Sbjct: 2000 --EGSVEATTSAGSG--NTAGTS-------GTGD--------TGPGNTAVSGTPVVSPGA 2040

Query: 390  SPGSDVSDSGGNTWSSDSGSGGGGKSADE 418
            +PG+  S + G     ++  G  GKS  +
Sbjct: 2041 TPGAPGSSTPGEADIGNTSFGKSGKSGHD 2069



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 101/432 (23%), Positives = 156/432 (36%), Gaps = 47/432 (10%)

Query: 32   GSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDR 91
            GSS+ G+ D    + +  FG  G++   S    +    +   T +     SS  S  +D 
Sbjct: 2046 GSSTPGEAD----IGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTD- 2100

Query: 92   TKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFG 151
                      A   A   SG      G+    T  G    G SSSG S            
Sbjct: 2101 ---------AASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGASNTPGATGS 2151

Query: 152  ATGEDEDKSRERWDAGN-SRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGI 210
            +TG+ +         GN  +S + P     SS +    G+ D   G  V+ +     T  
Sbjct: 2152 STGQTDTSGPSAKVTGNYGQSSEIPGTIKSSSDVSGTMGQSDTTSGPSVAVTR----TSE 2207

Query: 211  SSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGN 270
             S  V    T +S  SV +  G T   +E   + G +   +S L  +G    G    G +
Sbjct: 2208 QSSGV----TVASEPSVGVS-GTTGPLAE---ISGTTRPLVSGLRTTGSSAEGSGTTGPS 2259

Query: 271  GMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS-GSNQSG--DNGN 327
                SV+     +G G+   S          GL  T+ G   +F    G+++S   +   
Sbjct: 2260 SRE-SVTTRPLAEGSGTSGQSVTGSR---ATGLSATELGTTVSFTGGLGTSRSSARETRT 2315

Query: 328  SSKDFDGNGV-GDSSARNGFENSS-GIS---EDSGVILGSSDQHEVELSRTGGNRKRSSD 382
            +    DG+G  G S  R+G    S G++   E S  + G++     E   TG +   +  
Sbjct: 2316 TGPSADGSGTTGPSVVRSGTTRLSVGVTRATESSPGVTGTTTPSAEESRTTGPSVLVTGT 2375

Query: 383  PDEAGNLS--PGSDVSDSG------GNTWSSDSGSGGGGKSADELGVGASGLNEFGETGL 434
              ++G  S   G    +SG      G T  + +G G    S          +   G TG 
Sbjct: 2376 TGQSGQGSGTTGKSFIESGPSVVGSGTTGPTSAGLGTTAPSTRRSSTTKPSVGRTGTTGQ 2435

Query: 435  SGSEKGSHIPEA 446
            SG+E G+  P A
Sbjct: 2436 SGAESGTTEPSA 2447



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 86/363 (23%), Positives = 136/363 (37%), Gaps = 36/363 (9%)

Query: 101  GAPGKAEDKSGDSQDAGGSKSEDTPPG---GFFYGSSSSGDSDKKKPLFSFEFGATG-ED 156
            G  G     +G ++  G S  E    G   G    + SS     K  L +   G TG   
Sbjct: 3435 GVTGTTGPSAGVTRTTGLSAGETGTTGLSPGVTRTTRSSAGLTGKTGLSAGVTGKTGLSA 3494

Query: 157  EDKSRERWDAG-NSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
            E     R  AG    +  SP V TG++G   G        G     +   G TG+SS+  
Sbjct: 3495 EVTGTTRLSAGVTGTTGPSPGV-TGTTGTPAGVT------GTTELSAGVTGKTGLSSEVT 3547

Query: 216  EGNQTSSSGG---SVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGM 272
            E   T  S G   ++ +  G T    ++  V G +  S + +  + +   G+   G  G+
Sbjct: 3548 E--TTGLSYGVKRTIGLSAGSTGTSGQSAGVAGTTTLS-AEVTGTTRPSAGVT--GTTGL 3602

Query: 273  SGSVSAEAGFK----GFGSDSSSSVEKSWLFEFGLGETKGGAEFN-FRDSGSNQSGDNGN 327
            S  V+   G      G    S+   E +       G T+  A         +  +G  G 
Sbjct: 3603 SAEVTEITGISAVVTGTTGPSAGVTETTGSSAGVAGTTRLSAGVTGITGLSAGVTGTTGL 3662

Query: 328  SSKDFDGNG-----VGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSD 382
            S++     G      G +    G    +G+S+      GSS +    +   G  R  S+ 
Sbjct: 3663 STEVTGTTGPSAGATGTTGLSVGVTGITGLSDVVTETTGSSARSGTGIPSVGETRTTSTS 3722

Query: 383  PDEAGNLSPGSDVSDSGG----NTWSSDSGSGGGGKSADELGV-GASGLNEFGETGLSGS 437
             +E+    P + +  + G     T +++  +GG G +    GV G +GL+  GETG  GS
Sbjct: 3723 VEESRTTRPSAGIMGTNGLPAEVTGTTEPLAGGTGTTGILAGVTGTTGLSA-GETGKIGS 3781

Query: 438  EKG 440
              G
Sbjct: 3782 SAG 3784



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 106/479 (22%), Positives = 169/479 (35%), Gaps = 60/479 (12%)

Query: 17   KDGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKS----- 71
            K G    S  G  + G+SS G    +         S GETE   +    +G+ +S     
Sbjct: 2877 KSGTTGPSVIGTRTTGTSSGGSGATRS--------SGGETETTGQSAVKSGTTESFTRLT 2928

Query: 72   -EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP---- 126
                 + G   +S+ S     T PF   GL   G +      ++ +     +  PP    
Sbjct: 2929 RTSGQSAGMTGTSAQSAGVALTSPFVE-GLVTTGSSTVGLETTRPSAVGSGKTGPPVVKA 2987

Query: 127  ---GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRE----RWDAGNSRSEDSPAVGT 179
               G     + +SG S +         G TG     S+     R       + +  A G+
Sbjct: 2988 QTTGPSAGVTVTSGQSARMTGASGPSVGVTGTTGPASKGLGTIRPSVVGLETTELSAEGS 3047

Query: 180  GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKT--VEGNQTSSSGGSVSIDLGDTSFR 237
            G++G  +       + G  V+   S   TG +     V G    S  GSV+     T   
Sbjct: 3048 GTTGPPIVGETTVPSAGVTVTSGYSDRVTGATEPLAGVTGTIKPSVAGSVTTGPSVTGVE 3107

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGG----NGMSGSVSAEAGFKGFGSDSSSSV 293
            +  +   GG   +IS++  +G  G      G      G++G+ +  AG       S+  +
Sbjct: 3108 TTAKTTSGGLSTTISSVGGTGTTGQSPERSGTTGPFTGLTGTSAQSAGVTMTSIQSAGVL 3167

Query: 294  EKSWLFEFGLGETKGGAEFNFRDSG--SNQSGDNGNSSKDFDGNG---VGDSSAR----- 343
              + L   GLG T G A      +G  +  +G  G S++  +  G    G  + R     
Sbjct: 3168 VTTGLNVDGLG-TTGKALIGSGTTGLSAEATGTIGPSTEGLEKTGPSITGSGTTRPLVTE 3226

Query: 344  --NGFENSSGISEDSGVILG--SSDQHEVELSRTG--GNRKRSSDPDEAGNLSP------ 391
                  +S G S  S  + G  ++ Q   E   TG       +S P     ++P      
Sbjct: 3227 SWTAGTSSGGHSTTSPSVRGTETTGQSAAESVTTGPVTGYTETSGPSAGVTVTPRQSPTV 3286

Query: 392  ----GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
                GS  + S G T  S + SG    S+ +  +  S + E G T  S    G+  P A
Sbjct: 3287 TQTTGSSAAVS-GTTVQSLTVSGTTRPSSGQTEITGSSVKESGTTESSAVRSGTTGPTA 3344



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 63/285 (22%), Positives = 105/285 (36%), Gaps = 25/285 (8%)

Query: 179  TGSSGLKLGA-GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            T ++GL  G  G    + G   +   S G TG + ++ E   T+      S  L +T+  
Sbjct: 4370 TRTTGLSAGVTGTIGLSAGVTGTTRPSAGVTGTTGQSAEVTGTTEP----SAGLTETTGS 4425

Query: 238  SENQFVGGGSLNSISNLWD-----SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSS 292
            S       G L  ++         +G  G      G   +S  V+   G     ++++ S
Sbjct: 4426 STGVTGATGPLAGVTGTTGISTEVTGTTGPSARVTGTTVLSAGVTGITGLSAIVTETTGS 4485

Query: 293  VEKSWLFEFGLGETKGGAEFNFRDSGSNQ-----SGDNGNSSKDFDGNG-----VGDSSA 342
              +S      +GET G    +  +S + +     +G NG S++     G      G +  
Sbjct: 4486 SARSGTSTPSVGET-GTTRTSVEESRATRPSAGITGTNGQSAEVTWITGPLAGVTGTTGI 4544

Query: 343  RNGFENSSGISED-SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
              G   ++G+S   +G I  S+    +     G         +E G   P ++V+   G 
Sbjct: 4545 SAGVTGTTGLSAGVTGTIGSSAVVTGINGLSAGVTGTTGPSAEETGATGPSAEVT---GT 4601

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
            T  S   +G  G SA+  G         G  GLS    G+  P A
Sbjct: 4602 TGPSAEETGATGPSAEVTGTTGPSGGVTGTNGLSAEVTGTTGPSA 4646



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 61/272 (22%), Positives = 98/272 (36%), Gaps = 27/272 (9%)

Query: 191  GDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGD-TSFRSENQFVGGGSLN 249
            G +  G E +   + G    +  +V G  T+      S   G  T     +    G ++ 
Sbjct: 3100 GPSVTGVETTAKTTSGGLSTTISSVGGTGTTGQSPERSGTTGPFTGLTGTSAQSAGVTMT 3159

Query: 250  SISNLWDSGQEGFGINEIGGNGM----SGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGE 305
            SI +       G  ++ +G  G     SG+    A   G    S+  +EK+     G G 
Sbjct: 3160 SIQSAGVLVTTGLNVDGLGTTGKALIGSGTTGLSAEATGTIGPSTEGLEKTGPSITGSGT 3219

Query: 306  TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENS--SGISEDSGVILGSS 363
            T+     ++  +    SG +  +S    G      SA         +G +E SG   G +
Sbjct: 3220 TRPLVTESW--TAGTSSGGHSTTSPSVRGTETTGQSAAESVTTGPVTGYTETSGPSAGVT 3277

Query: 364  --DQHEVELSRTGGNRKRSSD-------------PDEAGNLSPGSDVSDSGGNTWSSDSG 408
               +    +++T G+    S              P        GS V +SG  T SS   
Sbjct: 3278 VTPRQSPTVTQTTGSSAAVSGTTVQSLTVSGTTRPSSGQTEITGSSVKESG-TTESSAVR 3336

Query: 409  SGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
            SG  G +A     G +G +  G TG++GS  G
Sbjct: 3337 SGTTGPTAGV--TGTNGPSSAGVTGITGSSPG 3366



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 67/286 (23%), Positives = 111/286 (38%), Gaps = 23/286 (8%)

Query: 166  AGNSRSEDSPAVGTGSSGLKLGA-GKGDAAFGFEVSDSNSFGDTGIS--SKTVEGNQTSS 222
            AG + +  S A GTG+ GL  G  G   ++ G   +   S G TGI+  S  V G    S
Sbjct: 3853 AGVTGTTGSLAGGTGTIGLSAGVTGTTGSSAGVTGTTGLSAGVTGIAGLSAGVTGITGPS 3912

Query: 223  SG--GSVSIDLG---DTSFRSENQFVGG------GSLNSISNLWDSGQEGFGINEI--GG 269
            +G  G+ ++  G    T   +E   + G      G+    + + ++ +   G+       
Sbjct: 3913 AGVTGTTTVSAGVTGTTGLSAEATEITGLSAGVTGTTGLSAGVTETIRLSAGVTGTIRSS 3972

Query: 270  NGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
             G++G     AG  G    S+     + L   G+ ET G +      +G +  G  G + 
Sbjct: 3973 AGVTGITGLSAGVTGTTGPSAGVTGSTGLLA-GVTETTGQSAKVTGTTGQSV-GVTGTTR 4030

Query: 330  KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
                  G+   SA  G   ++G+S  +G+   S++         G            G  
Sbjct: 4031 SSGGVTGITGLSA--GVTGTNGLSAVTGMTGLSAEVTGTTGLSVGVTGIAGLSAGVTGIT 4088

Query: 390  SPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLS 435
             P + ++   G T  S   +G  G SA+  G+        G+TGLS
Sbjct: 4089 GPSAGIT---GTTTISAGVTGTSGLSAEATGITGLSAGVTGKTGLS 4131



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 66/274 (24%), Positives = 104/274 (37%), Gaps = 33/274 (12%)

Query: 179  TGSSGLKLGAGKG-DAAFGFEVSDSNSFGDTGIS--SKTVEGNQTSSSG--GSVSIDLGD 233
            TG++GL  G  +    + G   +  +S G TGI+  S  V G    S+G  GS  +  G 
Sbjct: 3946 TGTTGLSAGVTETIRLSAGVTGTIRSSAGVTGITGLSAGVTGTTGPSAGVTGSTGLLAGV 4005

Query: 234  TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSV 293
            T    ++  V G +  S+     +   G G+  I   G+S  V+   G       +  S 
Sbjct: 4006 TETTGQSAKVTGTTGQSVGVTGTTRSSG-GVTGI--TGLSAGVTGTNGLSAVTGMTGLSA 4062

Query: 294  EKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGV-GDSSARNGFENSSGI 352
            E +      +G T            +  +G  G S+      G+ G ++   G   +SG+
Sbjct: 4063 EVTGTTGLSVGVT------GIAGLSAGVTGITGPSA------GITGTTTISAGVTGTSGL 4110

Query: 353  SEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGG 412
            S ++  I G S       +   G    S+   E   LS     +++ G   SS   +G  
Sbjct: 4111 SAEATGITGLS-------AGVTGKTGLSAGVTETIGLS-----AEATGTIGSSPGVTGTT 4158

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
            G S    G+        G TGLS    G+  P A
Sbjct: 4159 GSSTGVTGITGLSAGVTGTTGLSTEVTGTTGPSA 4192



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 94/413 (22%), Positives = 148/413 (35%), Gaps = 40/413 (9%)

Query: 66   AGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGL-GAPGKAEDKSGDSQDAGGSKSEDT 124
            AG   +    AG    + SS+G +  T    S G+ G  G +   +G +  + G     T
Sbjct: 3863 AGGTGTIGLSAGVTGTTGSSAGVTGTTG--LSAGVTGIAGLSAGVTGITGPSAGVTGTTT 3920

Query: 125  PPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRE-RWDAGNSRSEDSPAVGTGSSG 183
               G    +  S ++ +   L +   G TG     +   R  AG + +  S A  TG +G
Sbjct: 3921 VSAGVTGTTGLSAEATEITGLSAGVTGTTGLSAGVTETIRLSAGVTGTIRSSAGVTGITG 3980

Query: 184  LKLGA-----------GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG 232
            L  G            G      G   +   S   TG + ++V    T+ S G V+   G
Sbjct: 3981 LSAGVTGTTGPSAGVTGSTGLLAGVTETTGQSAKVTGTTGQSVGVTGTTRSSGGVT---G 4037

Query: 233  DTSFRSENQFVGGGSLNSISNLWD-----SGQEGFGINEIGGNGMSGSVSA----EAGFK 283
             T   +     G   L++++ +       +G  G  +   G  G+S  V+      AG  
Sbjct: 4038 ITGLSAG--VTGTNGLSAVTGMTGLSAEVTGTTGLSVGVTGIAGLSAGVTGITGPSAGIT 4095

Query: 284  GFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSAR 343
            G  + S+     S L     G T   A    +   S    +    S +  G  +G S   
Sbjct: 4096 GTTTISAGVTGTSGLSAEATGITGLSAGVTGKTGLSAGVTETIGLSAEATGT-IGSSPGV 4154

Query: 344  NGFENSS----GISEDSGVILGSSDQHEVELSRTGGN----RKRSSDPDEAGNLSPGSDV 395
             G   SS    GI+  S  + G++         TG +    R         G     + V
Sbjct: 4155 TGTTGSSTGVTGITGLSAGVTGTTGLSTEVTGTTGPSAGVTRTTGLSAGVTGITGLSAIV 4214

Query: 396  SDSGGNTWSSDS--GSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
            +++ G++  S +  G+G  G SA   G   S     G TGLS    G+  P A
Sbjct: 4215 TETTGSSARSGTTGGTGTTGLSAGVTGTVGSSAVVTGTTGLSAGVTGTTGPSA 4267



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 66/310 (21%), Positives = 105/310 (33%), Gaps = 38/310 (12%)

Query: 166  AGNSRSEDSPAVGTGSSGLKLGA----GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTS 221
            AG + +  S A  TG++GL   A    G      G     +   G  G+S++  E    S
Sbjct: 4706 AGVTETIGSSAGVTGTNGLSAEATGTTGPSAGVTGTTGLSAGVTGTAGLSARVTESTGLS 4765

Query: 222  SS-GGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA 280
            +   G+  +  G T     +  + G +  S      +G            G++G++   A
Sbjct: 4766 AGVTGTTGLSAGVTGTTGPSAGITGTNGLSAEVTGTTGPLA---------GVTGTIGLSA 4816

Query: 281  GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFN-FRDSGSNQSGDNGNSSKDFDGNG--- 336
            G  G    S+   E + L     G  +  A         +  +G  G S+++    G   
Sbjct: 4817 GVTGIAGLSAGVTESTGLSAGVTGTIRSSAVVTGINGLSAGVTGTTGPSAEETGATGPSA 4876

Query: 337  --VGDSSARNGFENSSGIS-EDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGS 393
               G +    G   +SGIS E +G    S++   +     G      S     G   P +
Sbjct: 4877 EVTGTTGPSGGVTGTSGISAEVTGTTGPSAEVTGLPGVSAGVTGTIGSPAAVTGTTRPSA 4936

Query: 394  DVSDSGG----------------NTWSSDSG-SGGGGKSADELGVGASGLNEFGETGLSG 436
             V+   G                 T  S +G +G  G SA+            G TGLS 
Sbjct: 4937 VVTGISGLSAEVTGTTGLSAGVTETIGSSAGVTGTNGLSAEATETTGPSAGVTGTTGLSA 4996

Query: 437  SEKGSHIPEA 446
               G+  P A
Sbjct: 4997 GVTGTTGPSA 5006



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 68/300 (22%), Positives = 112/300 (37%), Gaps = 35/300 (11%)

Query: 174  SPAVGTGSSGLKLGAGKGDAAFGFEVSDSN--SFGDTGISSKTVEGNQTS--SSG--GSV 227
            SPA  TG++ L      G      EV+ +   S G TGI+  + E  +T+  S+G  G++
Sbjct: 4325 SPAGVTGTTQLS-AVVTGITGLSAEVTGTTGLSAGVTGITGLSAEVTRTTGLSAGVTGTI 4383

Query: 228  SIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGN-----GMSGSVSAEAGF 282
             +  G T     +  V G +  S + +  + +   G+ E  G+     G +G ++   G 
Sbjct: 4384 GLSAGVTGTTRPSAGVTGTTGQS-AEVTGTTEPSAGLTETTGSSTGVTGATGPLAGVTGT 4442

Query: 283  KGFGSD------SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
             G  ++       S+ V  + +   G+    G +      +GS  S  +G S+      G
Sbjct: 4443 TGISTEVTGTTGPSARVTGTTVLSAGVTGITGLSAIVTETTGS--SARSGTSTPSVGETG 4500

Query: 337  VGDSSARNGFENSSGISEDSGVILGSSDQHEVE-----LSRTGGNRKRSSDPDEAGNLSP 391
                + R   E S      +G+   +    EV      L+   G    S+       LS 
Sbjct: 4501 ----TTRTSVEESRATRPSAGITGTNGQSAEVTWITGPLAGVTGTTGISAGVTGTTGLSA 4556

Query: 392  GSDVSDSGGNTWSSDSGSGGG-----GKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
            G   +       +  +G   G     G SA+E G         G TG S  E G+  P A
Sbjct: 4557 GVTGTIGSSAVVTGINGLSAGVTGTTGPSAEETGATGPSAEVTGTTGPSAEETGATGPSA 4616



>gi|4505285|ref|NP_002448.1|   mucin 2 [Homo sapiens]
 gi|454154|gb|AAB95295.1|   mucin [Homo sapiens]
 gi|2506877|sp|Q02817|MUC2_HUMAN   Mucin 2 precursor (Intestinal mucin 2)
          Length = 5179

 Score =  270 bits (691), Expect = 1e-71
 Identities = 133/351 (37%), Positives = 191/351 (54%), Gaps = 29/351 (8%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ---- 864
            V GC CPD +  +  G CV++ +C C  N+++   G  I +D N C C+ G  +C     
Sbjct: 797  VSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856

Query: 865  ------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS--TRNIP-----VFD 905
                        I  D    +  G   YV   D   Q  +  + S  T N+P     V  
Sbjct: 857  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 916

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNAN-----AYSIHTVGLYLILKFQNGIIVIWDKNTR 960
             + I +  G+ T +K  +  +  +  +     AY+   VG YL+++   GIIVIWDK T 
Sbjct: 917  SKAIKIFMGR-TELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTT 975

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF 1020
            + + L P++ G VCGLCGN +    +DFTTR   V S  L+FGNSWK +  C D      
Sbjct: 976  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 1035

Query: 1021 PCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            PC  NP+ ++WA ++C IL+ S F  CH+KVDP  +++ C+ ++C+CD  G    FC+AV
Sbjct: 1036 PCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAV 1095

Query: 1081 AMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
            A YA+ C+  G CV WR P+LCP++CDYYN P EC WHYEPCG  + +TC+
Sbjct: 1096 ASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146



 Score =  221 bits (563), Expect = 7e-57
 Identities = 108/289 (37%), Positives = 161/289 (55%), Gaps = 11/289 (3%)

Query: 606 IFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
           +F  SS ++ V     V+LQ+Q+ PVMQL+V++         GLCG++N    DDF ++ 
Sbjct: 484 VFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTAS 543

Query: 666 NILEKTSQAFANSWEMMSCPKG------NPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
            ++E T   FAN+W+  S          +P S ++IE   +AE  C +L  +  P   CH
Sbjct: 544 GLVEATGAGFANTWKAQSTCHDKLDWLDDPCS-LNIESANYAEHWCSLLKKTETPFGRCH 602

Query: 720 PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCP 776
             V+P  Y++ CK  TC C+N++DCLC  L +Y +AC  K   + GWR  +C     SCP
Sbjct: 603 SAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCP 662

Query: 777 SGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 836
           +  VF YN+  C  +CRSLSE D  C     PVDGC CPD  + + +G CV  ++C CY 
Sbjct: 663 NSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYH 722

Query: 837 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD 885
               ++ G ++   + +CVCRDG L C+  I L  Q+C+    ++DCS+
Sbjct: 723 RGLYLEAGDVVVRQEERCVCRDGRLHCR-QIRLIGQSCTAPKIHMDCSN 770



 Score =  154 bits (388), Expect = 1e-36
 Identities = 138/500 (27%), Positives = 204/500 (40%), Gaps = 60/500 (12%)

Query: 646  TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN----PSSCISIEK 697
            T GLCG YN         S  +L    + F N  ++    + C        P+SC     
Sbjct: 165  TCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCEDPEEEVAPASCSEHRA 223

Query: 698  EKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 757
            E      C  LL +    A C  +V  +PY   C++  C C     C+C+ +  + + C+
Sbjct: 224  E------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCS 276

Query: 758  EKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPD 816
                    WRT  LC  +CP  LV+  +   C  +C   S  + S   E+  +DGC CP+
Sbjct: 277  HAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC---SHLEVSSLCEEHRMDGCFCPE 333

Query: 817  AMYQNNEGN--CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ---IPIDLTL 871
                ++ G+  CV  SQC C ++  +  PG+ I  D  +CVC  G  +C+    P    L
Sbjct: 334  GTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCAL 393

Query: 872  QNCS-------------GGAEYV----DCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDG 914
            +  S             G   YV    D +D  A       C + +        ++L D 
Sbjct: 394  EGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVLLADK 453

Query: 915  KVTAVKSTESKKCELNANAYSI-HTVGLYLILKFQN-GIIVIWDKNTRLS---------- 962
            K  AV         LN    ++ H    + + +  +  I+V      RL           
Sbjct: 454  KKNAVVFKSDGSVLLNQLQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLF 513

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVA-QTFP 1021
            V LD    G+V GLCGN NG   DDF T    V +    F N+WK    C D +     P
Sbjct: 514  VTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSTCHDKLDWLDDP 573

Query: 1022 CDSNPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1079
            C  N     +A   C +L+  ++ F  CH+ VDP+ Y+  C  + C C      L  C A
Sbjct: 574  CSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL--CAA 631

Query: 1080 VAMYAEACSAVGVCV-SWRK 1098
            ++ YA AC+A GV +  WR+
Sbjct: 632  LSSYARACTAKGVMLWGWRE 651



 Score =  105 bits (263), Expect = 4e-22
 Identities = 69/243 (28%), Positives = 119/243 (48%), Gaps = 25/243 (10%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCP--KGNPS 690
            +++ + P+      GLCG++++++ +DF +  +++  +   F NSW E  +CP    NP 
Sbjct: 976  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 1035

Query: 691  SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCT 747
             C ++  +  +AE+ C IL   S   + CH  V+PKP++E C   +C+C+   D  C C+
Sbjct: 1036 PCSLNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 1093

Query: 748  ILGNYVKACAEKETYIVGWRT-GLCEHSC-----PSGLVFKYNVKACNS--SCRSLSERD 799
             + +Y + C  KE   V WRT  LC   C     P    + Y      S  +CR+++   
Sbjct: 1094 AVASYAQECT-KEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIH 1152

Query: 800  RSCDVEDVPVDGC--TCPD--AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NK 853
             +  V    ++GC   CP    +Y+ +   CV   +C CY+ D    PG  +  ++    
Sbjct: 1153 SNISVS--YLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS 1210

Query: 854  CVC 856
            CVC
Sbjct: 1211 CVC 1213



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 31/252 (12%)

Query: 636  VSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGNP 689
            V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  + 
Sbjct: 4607 VRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSS 4666

Query: 690  SS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC 738
            ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C  
Sbjct: 4667 TTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCFM 4724

Query: 739  ENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRSL 795
              S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S 
Sbjct: 4725 PGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 4782

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHIDDNKC 854
            S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   C
Sbjct: 4783 SSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNC 4838

Query: 855  VCRDG--ILLCQ 864
            VC +G   ++CQ
Sbjct: 4839 VCLEGGSGIICQ 4850



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 49/162 (30%), Positives = 71/162 (43%), Gaps = 13/162 (8%)

Query: 950  GIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            G+ ++W++   L + LD  +    CGLCG+ NG L+         V    LEFGN  K +
Sbjct: 142  GLTLMWNREDALMLELDTKFRNHTCGLCGDYNG-LQSYSEFLSDGVLFSPLEFGNMQKIN 200

Query: 1010 QE---CSDTVAQTFPCDSNPYCKAWAVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEAC 1065
            Q    C D   +  P   + +       +CE +L    F DC + V    Y   C ++ C
Sbjct: 201  QPDVVCEDPEEEVAPASCSEH-----RAECERLLTAEAFADCQDLVPLEPYLRACQQDRC 255

Query: 1066 ACDMEGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYC 1106
             C   G     C+ VA ++  CS A G   +WR   LCP  C
Sbjct: 256  RC--PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTC 295



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 24/184 (13%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----------SQECSDTVAQTFPCD- 1023
            G CG       DD       + S      + W            S   +   A T P   
Sbjct: 4620 GQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGG 4679

Query: 1024 -SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
             + P+        C++++DS F  CH  V P  Y+D C+ ++C   M G  L  C ++  
Sbjct: 4680 KTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCF--MPGSSLE-CASLQA 4736

Query: 1083 YAEACSAVGVCVSWRK--PNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YA  C+   +C+ WR      C V C  +         Y+ CG     TCK     Q  +
Sbjct: 4737 YAALCAQQNICLDWRNHTHGACLVECPSHR-------EYQACGPAEEPTCKSSSSQQNNT 4789

Query: 1141 SLLE 1144
             L+E
Sbjct: 4790 VLVE 4793



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 492  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
            C  I  + F +C  +    + Y   C+ + C     +  C +    + LCA         
Sbjct: 4693 CQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAALCAQQN--ICLD 4749

Query: 552  WRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE-CVSGCTCPE 601
            WR+ +   C  + CP    Y+ CGP+   TC + +  Q++   V GC CPE
Sbjct: 4750 WRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 4799



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 9/124 (7%)

Query: 485 CEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRD-KTSTCDTYSELSRLCA 542
           C +    C +++    F  C  +  L   Y   C  + C+     T  C T +E SR C+
Sbjct: 218 CSEHRAECERLLTAEAFADCQDLVPLE-PYLRACQQDRCRCPGGDTCVCSTVAEFSRQCS 276

Query: 543 SDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPFQDSECVSGCTCP 600
             G G   +WR+ +  +C  + CP   +Y E G     TCS+  V+   +   + GC CP
Sbjct: 277 HAG-GRPGNWRTAT--LC-PKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCP 332

Query: 601 EDKI 604
           E  +
Sbjct: 333 EGTV 336



>gi|186396|gb|AAA59163.1|   mucin
          Length = 1270

 Score =  270 bits (691), Expect = 1e-71
 Identities = 133/351 (37%), Positives = 191/351 (54%), Gaps = 29/351 (8%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ---- 864
            V GC CPD +  +  G CV++ +C C  N+++   G  I +D N C C+ G  +C     
Sbjct: 172  VSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 231

Query: 865  ------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS--TRNIP-----VFD 905
                        I  D    +  G   YV   D   Q  +  + S  T N+P     V  
Sbjct: 232  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 291

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNAN-----AYSIHTVGLYLILKFQNGIIVIWDKNTR 960
             + I +  G+ T +K  +  +  +  +     AY+   VG YL+++   GIIVIWDK T 
Sbjct: 292  SKAIKIFMGR-TELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTT 350

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF 1020
            + + L P++ G VCGLCGN +    +DFTTR   V S  L+FGNSWK +  C D      
Sbjct: 351  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 410

Query: 1021 PCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            PC  NP+ ++WA ++C IL+ S F  CH+KVDP  +++ C+ ++C+CD  G    FC+AV
Sbjct: 411  PCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAV 470

Query: 1081 AMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
            A YA+ C+  G CV WR P+LCP++CDYYN P EC WHYEPCG  + +TC+
Sbjct: 471  ASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 521



 Score =  125 bits (313), Expect = 7e-28
 Identities = 59/146 (40%), Positives = 83/146 (56%), Gaps = 4/146 (2%)

Query: 743 DCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCPSGLVFKYNVKACNSSCRSLSERD 799
           DCLC  L +Y +AC  K   + GWR  +C     SCP+  VF YN+  C  +CRSLSE D
Sbjct: 1   DCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEAD 60

Query: 800 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
             C     PVDGC CPD  + + +G CV  ++C CY     ++ G ++   + +CVCRDG
Sbjct: 61  SHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDG 120

Query: 860 ILLCQIPIDLTLQNCSGGAEYVDCSD 885
            L C+  I L  Q+C+    ++DCS+
Sbjct: 121 RLHCR-QIRLIGQSCTAPKIHMDCSN 145



 Score =  105 bits (263), Expect = 4e-22
 Identities = 69/243 (28%), Positives = 119/243 (48%), Gaps = 25/243 (10%)

Query: 634 LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCP--KGNPS 690
           +++ + P+      GLCG++++++ +DF +  +++  +   F NSW E  +CP    NP 
Sbjct: 351 VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 410

Query: 691 SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCT 747
            C ++  +  +AE+ C IL   S   + CH  V+PKP++E C   +C+C+   D  C C+
Sbjct: 411 PCSLNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 468

Query: 748 ILGNYVKACAEKETYIVGWRT-GLCEHSC-----PSGLVFKYNVKACNS--SCRSLSERD 799
            + +Y + C  KE   V WRT  LC   C     P    + Y      S  +CR+++   
Sbjct: 469 AVASYAQECT-KEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIH 527

Query: 800 RSCDVEDVPVDGC--TCPD--AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NK 853
            +  V    ++GC   CP    +Y+ +   CV   +C CY+ D    PG  +  ++    
Sbjct: 528 SNISVS--YLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS 585

Query: 854 CVC 856
           CVC
Sbjct: 586 CVC 588



>gi|2135765|pir||A43932   mucin 2 precursor, intestinal - human (fragments)
          Length = 3020

 Score =  270 bits (691), Expect = 1e-71
 Identities = 133/351 (37%), Positives = 191/351 (54%), Gaps = 29/351 (8%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ---- 864
            V GC CPD +  +  G CV++ +C C  N+++   G  I +D N C C+ G  +C     
Sbjct: 797  VSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVC 856

Query: 865  ------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS--TRNIP-----VFD 905
                        I  D    +  G   YV   D   Q  +  + S  T N+P     V  
Sbjct: 857  HGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTC 916

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNAN-----AYSIHTVGLYLILKFQNGIIVIWDKNTR 960
             + I +  G+ T +K  +  +  +  +     AY+   VG YL+++   GIIVIWDK T 
Sbjct: 917  SKAIKIFMGR-TELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTT 975

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF 1020
            + + L P++ G VCGLCGN +    +DFTTR   V S  L+FGNSWK +  C D      
Sbjct: 976  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 1035

Query: 1021 PCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            PC  NP+ ++WA ++C IL+ S F  CH+KVDP  +++ C+ ++C+CD  G    FC+AV
Sbjct: 1036 PCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAV 1095

Query: 1081 AMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
            A YA+ C+  G CV WR P+LCP++CDYYN P EC WHYEPCG  + +TC+
Sbjct: 1096 ASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCR 1146



 Score =  221 bits (563), Expect = 7e-57
 Identities = 108/289 (37%), Positives = 161/289 (55%), Gaps = 11/289 (3%)

Query: 606 IFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
           +F  SS ++ V     V+LQ+Q+ PVMQL+V++         GLCG++N    DDF ++ 
Sbjct: 484 VFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTAS 543

Query: 666 NILEKTSQAFANSWEMMSCPKG------NPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
            ++E T   FAN+W+  S          +P S ++IE   +AE  C +L  +  P   CH
Sbjct: 544 GLVEATGAGFANTWKAQSTCHDKLDWLDDPCS-LNIESANYAEHWCSLLKKTETPFGRCH 602

Query: 720 PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SCP 776
             V+P  Y++ CK  TC C+N++DCLC  L +Y +AC  K   + GWR  +C     SCP
Sbjct: 603 SAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCP 662

Query: 777 SGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 836
           +  VF YN+  C  +CRSLSE D  C     PVDGC CPD  + + +G CV  ++C CY 
Sbjct: 663 NSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYH 722

Query: 837 NDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSD 885
               ++ G ++   + +CVCRDG L C+  I L  Q+C+    ++DCS+
Sbjct: 723 RGLYLEAGDVVVRQEERCVCRDGRLHCR-QIRLIGQSCTAPKIHMDCSN 770



 Score =  154 bits (388), Expect = 1e-36
 Identities = 138/500 (27%), Positives = 204/500 (40%), Gaps = 60/500 (12%)

Query: 646  TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN----PSSCISIEK 697
            T GLCG YN         S  +L    + F N  ++    + C        P+SC     
Sbjct: 165  TCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCEDPEEEVAPASCSEHRA 223

Query: 698  EKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 757
            E      C  LL +    A C  +V  +PY   C++  C C     C+C+ +  + + C+
Sbjct: 224  E------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCS 276

Query: 758  EKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPD 816
                    WRT  LC  +CP  LV+  +   C  +C   S  + S   E+  +DGC CP+
Sbjct: 277  HAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC---SHLEVSSLCEEHRMDGCFCPE 333

Query: 817  AMYQNNEGN--CVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ---IPIDLTL 871
                ++ G+  CV  SQC C ++  +  PG+ I  D  +CVC  G  +C+    P    L
Sbjct: 334  GTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPGTCAL 393

Query: 872  QNCS-------------GGAEYV----DCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDG 914
            +  S             G   YV    D +D  A       C + +        ++L D 
Sbjct: 394  EGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTDKQTCLKTVVLLADK 453

Query: 915  KVTAVKSTESKKCELNANAYSI-HTVGLYLILKFQN-GIIVIWDKNTRLS---------- 962
            K  AV         LN    ++ H    + + +  +  I+V      RL           
Sbjct: 454  KKNAVVFKSDGSVLLNQLQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLF 513

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVA-QTFP 1021
            V LD    G+V GLCGN NG   DDF T    V +    F N+WK    C D +     P
Sbjct: 514  VTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSTCHDKLDWLDDP 573

Query: 1022 CDSNPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1079
            C  N     +A   C +L+  ++ F  CH+ VDP+ Y+  C  + C C      L  C A
Sbjct: 574  CSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCL--CAA 631

Query: 1080 VAMYAEACSAVGVCV-SWRK 1098
            ++ YA AC+A GV +  WR+
Sbjct: 632  LSSYARACTAKGVMLWGWRE 651



 Score =  105 bits (263), Expect = 4e-22
 Identities = 69/243 (28%), Positives = 119/243 (48%), Gaps = 25/243 (10%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCP--KGNPS 690
            +++ + P+      GLCG++++++ +DF +  +++  +   F NSW E  +CP    NP 
Sbjct: 976  VFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPE 1035

Query: 691  SC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCT 747
             C ++  +  +AE+ C IL   S   + CH  V+PKP++E C   +C+C+   D  C C+
Sbjct: 1036 PCSLNPHRRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 1093

Query: 748  ILGNYVKACAEKETYIVGWRT-GLCEHSC-----PSGLVFKYNVKACNS--SCRSLSERD 799
             + +Y + C  KE   V WRT  LC   C     P    + Y      S  +CR+++   
Sbjct: 1094 AVASYAQECT-KEGACVFWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIH 1152

Query: 800  RSCDVEDVPVDGC--TCPD--AMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NK 853
             +  V    ++GC   CP    +Y+ +   CV   +C CY+ D    PG  +  ++    
Sbjct: 1153 SNISVS--YLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS 1210

Query: 854  CVC 856
            CVC
Sbjct: 1211 CVC 1213



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 31/252 (12%)

Query: 636  VSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGNP 689
            V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  + 
Sbjct: 2448 VRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSS 2507

Query: 690  SS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC 738
            ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C  
Sbjct: 2508 TTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCFM 2565

Query: 739  ENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRSL 795
              S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S 
Sbjct: 2566 PGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 2623

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHIDDNKC 854
            S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   C
Sbjct: 2624 SSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNC 2679

Query: 855  VCRDG--ILLCQ 864
            VC +G   ++CQ
Sbjct: 2680 VCLEGGSGIICQ 2691



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 49/162 (30%), Positives = 71/162 (43%), Gaps = 13/162 (8%)

Query: 950  GIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            G+ ++W++   L + LD  +    CGLCG+ NG L+         V    LEFGN  K +
Sbjct: 142  GLTLMWNREDALMLELDTKFRNHTCGLCGDYNG-LQSYSEFLSDGVLFSPLEFGNMQKIN 200

Query: 1010 QE---CSDTVAQTFPCDSNPYCKAWAVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEAC 1065
            Q    C D   +  P   + +       +CE +L    F DC + V    Y   C ++ C
Sbjct: 201  QPDVVCEDPEEEVAPASCSEH-----RAECERLLTAEAFADCQDLVPLEPYLRACQQDRC 255

Query: 1066 ACDMEGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYC 1106
             C   G     C+ VA ++  CS A G   +WR   LCP  C
Sbjct: 256  RC--PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTC 295



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 24/184 (13%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----------SQECSDTVAQTFPCD- 1023
            G CG       DD       + S      + W            S   +   A T P   
Sbjct: 2461 GQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGG 2520

Query: 1024 -SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
             + P+        C++++DS F  CH  V P  Y+D C+ ++C   M G  L  C ++  
Sbjct: 2521 KTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCF--MPGSSLE-CASLQA 2577

Query: 1083 YAEACSAVGVCVSWRK--PNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YA  C+   +C+ WR      C V C  +         Y+ CG     TCK     Q  +
Sbjct: 2578 YAALCAQQNICLDWRNHTHGACLVECPSHR-------EYQACGPAEEPTCKSSSSQQNNT 2630

Query: 1141 SLLE 1144
             L+E
Sbjct: 2631 VLVE 2634



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 492  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
            C  I  + F +C  +    + Y   C+ + C     +  C +    + LCA         
Sbjct: 2534 CQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAALCAQQN--ICLD 2590

Query: 552  WRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE-CVSGCTCPE 601
            WR+ +   C  + CP    Y+ CGP+   TC + +  Q++   V GC CPE
Sbjct: 2591 WRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 2640



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 9/124 (7%)

Query: 485 CEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRD-KTSTCDTYSELSRLCA 542
           C +    C +++    F  C  +  L   Y   C  + C+     T  C T +E SR C+
Sbjct: 218 CSEHRAECERLLTAEAFADCQDLVPLE-PYLRACQQDRCRCPGGDTCVCSTVAEFSRQCS 276

Query: 543 SDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPFQDSECVSGCTCP 600
             G G   +WR+ +  +C  + CP   +Y E G     TCS+  V+   +   + GC CP
Sbjct: 277 HAG-GRPGNWRTAT--LC-PKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCP 332

Query: 601 EDKI 604
           E  +
Sbjct: 333 EGTV 336



>gi|17384254|emb|CAC83674.1|   mucin 5 [Homo sapiens]
          Length = 2448

 Score =  268 bits (686), Expect = 4e-71
 Identities = 137/380 (36%), Positives = 192/380 (50%), Gaps = 46/380 (12%)

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 847
            C  SC +L   D +C      V GC CPD +  + EG C+    C C  N+   + G+ I
Sbjct: 823  CQKSCHTL---DMTCYSPQC-VPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 878

Query: 848  HIDDNKCVCRDGILLCQIPIDLTLQNCS--GGAEYV-----------DCSDPKAQRR--- 891
             +  N C C   +  C    D  L  C+  G   Y+           DC     Q     
Sbjct: 879  RVGCNTCTCDSRMWRC--TDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGG 936

Query: 892  -------------------TNRTCSTRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNAN 932
                               T  TCS           + L  GKV  + + ES++      
Sbjct: 937  KDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEVIGTDESQEV----- 991

Query: 933  AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 992
             Y+I  +G+YL++    G++++WDK T + + L P + G+VCGLCGN +    +DF TR 
Sbjct: 992  PYTIQQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRS 1051

Query: 993  SSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVD 1052
             SV    LEFGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  CH  V+
Sbjct: 1052 RSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVE 1111

Query: 1053 PSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAP 1112
            P+ Y++ C+ +ACACD  G    FCTAVA YA+AC  VG+CV  R P++CP++CDYYN  
Sbjct: 1112 PARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCVCLRTPSICPLFCDYYNPE 1171

Query: 1113 GECRWHYEPCGTVTAKTCKD 1132
            G+C WHY+PCG    +TC++
Sbjct: 1172 GQCEWHYQPCGVPCLRTCRN 1191



 Score =  214 bits (544), Expect = 1e-54
 Identities = 113/330 (34%), Positives = 169/330 (51%), Gaps = 21/330 (6%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           + IF  S+ ++  +T   ++L +Q VP MQL++ + P     T GLCG++N+   DDF +
Sbjct: 525 VTIFRPSTFFIIAQTSLGLQLNLQPVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRT 584

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T+ AF N+++  + CP    S      +S+E EK+A+  C  L D+ GP   C
Sbjct: 585 LSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRC 644

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SC 775
           H  V P  Y+  C   TC CE S+DCLC  L +YV ACA K   + GWR G+C     +C
Sbjct: 645 HAAVKPGTYYSNCVFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 704

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P  + + Y+V  C  +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY
Sbjct: 705 PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCY 764

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDP---KAQ 889
               ++  G+ +H     C C  G L C   Q P  +    C+    + DC +       
Sbjct: 765 HRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTG 820

Query: 890 RRTNRTCSTRNIPVFDDQNI---VLQDGKV 916
               ++C T ++  +  Q +   V  DG V
Sbjct: 821 AGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 850



 Score =  138 bits (348), Expect = 6e-32
 Identities = 150/569 (26%), Positives = 213/569 (37%), Gaps = 77/569 (13%)

Query: 606  IFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
            +   SSSY +VE    + L         L + +       T GLCG +N       + S 
Sbjct: 169  LIQQSSSYTKVEARLGLVLMWNHDD--SLLLELDTKYANKTCGLCGDFNGMPVVSELLSH 226

Query: 666  NILEKTSQAFANSWEM----------MSCPKGNPSSCISIEKEKFAERHCGILLDSSGPL 715
            N  + T   F N  +M          +  P  N S+   I         C  LL      
Sbjct: 227  NT-KLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LF 275

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCE 772
            + C  +V+   Y E C++  C CE++    C+C  L  Y + C         WR    C 
Sbjct: 276  SGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP 335

Query: 773  HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN--CVLKS 830
              CP+ + +      C  +C S  E  R+C  ED  V GC CP+    ++ G   CV  S
Sbjct: 336  QKCPNNMQYHECRSPCADTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-IPIDLTLQNCSG-------GAEYV- 881
            +C C  N     PG     D   C C  G   CQ +P   T     G       G +Y  
Sbjct: 393  KCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPDTCSVLGGAHFSTFDGKQYTV 452

Query: 882  --DCS----DPKAQRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESKKCELN 930
              DCS     P            R   + D +  +       DG  T V    S +  LN
Sbjct: 453  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLN 512

Query: 931  ----------ANAYSIHTVGLYLILKFQNGIIVIWD--KNTRLSVILDPNWNGKVCGLCG 978
                      AN         ++I +   G+ +        +L + L P   G+ CGLCG
Sbjct: 513  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQPVPTMQLFMQLAPKLRGQTCGLCG 572

Query: 979  NNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF--PCDSNPYCKAWAVRKC 1036
            N N    DDF T    V + A  F N++KT   C + +  +F  PC  +   + +A   C
Sbjct: 573  NFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN-IRNSFEDPCSLSVENEKYAQHWC 631

Query: 1037 EILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV 1094
              L D+   F  CH  V P  Y+  C+ + C C+     L  C A++ Y  AC+A GV +
Sbjct: 632  SQLTDADGPFGRCHAAVKPGTYYSNCVFDTCNCERSEDCL--CAALSSYVHACAAKGVQL 689

Query: 1095 -SWR-----KP-NLCPVYCDYYNAPGECR 1116
              WR     KP   CP    Y+     C+
Sbjct: 690  GGWRDGVCTKPMTTCPKSMTYHYHVSTCQ 718



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 64/254 (25%), Positives = 112/254 (44%), Gaps = 29/254 (11%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----N 688
            +++++ P       GLCG++++ A +DF +    +      F NSW++  SCP      +
Sbjct: 1020 IFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKD 1079

Query: 689  PSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CL 745
            P +     K  +A++ C IL    GP  A+CH  V P  Y+E C    C C++  D  C 
Sbjct: 1080 PCTANPFRKS-WAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1135

Query: 746  CTILGNYVKACAEKETYIVGWRTGLCEHSC----PSGLVFKYNVKACNSSCRSLSERDRS 801
            CT +  Y +AC E    +      +C   C    P G   +++ + C   C       R 
Sbjct: 1136 CTAVAAYAQACHEVGLCVCLRTPSICPLFCDYYNPEGQC-EWHYQPCGVPCLRTCRNPRG 1194

Query: 802  CDVEDV-PVDGC--TCPD--AMYQNNEGNCVLKSQCD-----CYINDEVMQPGKLIHIDD 851
              + DV  ++GC   CP    ++  ++  CV           C+++ +  +PG ++  D 
Sbjct: 1195 DCLRDVRGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1254

Query: 852  N--KCVCRDGILLC 863
            N   C+C +  + C
Sbjct: 1255 NCQSCLCTERGVEC 1268



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 24/264 (9%)

Query: 877  GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSI 936
            GA Y D +  + +R       T +  +     +V+Q  K + + +        + +   I
Sbjct: 112  GAAYEDFNI-QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLI 170

Query: 937  HTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNG-DLKDDFTTRYSSV 995
                 Y  ++ + G++++W+ +  L + LD  +  K CGLCG+ NG  +  +  +  + +
Sbjct: 171  QQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL 230

Query: 996  ASGALEFGNSWK---TSQECSDTVAQTFPCDSNPY--CKAWAVRKCEILRDSTFRDCHNK 1050
                +EFGN  K    +++C D V +     S  +  C+       E+L    F  C   
Sbjct: 231  T--PMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGICE-------ELLHGQLFSGCVAL 281

Query: 1051 VDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYY 1109
            VD  +Y + C ++ C C+        C  +A Y+  C+ A G+   WR P+ CP  C   
Sbjct: 282  VDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNN 341

Query: 1110 NAPGECRWHYEPCGTVTAKTCKDQ 1133
                ECR    PC    A TC +Q
Sbjct: 342  MQYHECR---SPC----ADTCSNQ 358



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 11/137 (8%)

Query: 474 CPNAVGKSYEVCEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRDK---TS 529
           C + V +    C  G   C +++ G  F  C  +  + + Y   C  + C   D    + 
Sbjct: 248 CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGS-YLEACRQDLCFCEDTDLLSC 306

Query: 530 TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ 589
            C T +E SR C   G G  + WR      C  Q+CP    Y EC      TCSN    +
Sbjct: 307 VCHTLAEYSRQCTHAG-GLPQDWRGPD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSR 362

Query: 590 --DSECVSGCTCPEDKI 604
             +  CV+GC CPE  +
Sbjct: 363 ACEDHCVAGCFCPEGTV 379



>gi|3192971|gb|AAC19168.1|   gastric mucin [Homo sapiens]
          Length = 1373

 Score =  265 bits (678), Expect = 3e-70
 Identities = 137/381 (35%), Positives = 194/381 (50%), Gaps = 47/381 (12%)

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 847
            C  SC +L   D +C      V GC CPD +  + EG C+    C C  N+   + G+ I
Sbjct: 825  CQKSCHTL---DMTCYSPQC-VPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 880

Query: 848  HIDDNKCVCRDGILLCQIPIDLTLQNCS--GGAEYVD-----------------CSDPKA 888
             +  N C C   +  C    D  L  C+  G   Y+                  C    A
Sbjct: 881  RVGCNTCTCDSRMWRCTD--DPCLATCAVYGDGHYLTFDGQSYSFNEETASTRWCRTAVA 938

Query: 889  QRRTNRT---CSTRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNA 931
             +   RT    S R  P               + +  + L  GKV  + + ES++     
Sbjct: 939  GKTAPRTPFVLSPRTSPAAPQGPPAPRPSRFSWGNFELKLSHGKVEVIGTDESQEVP--- 995

Query: 932  NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 991
              Y+I  +G+YL++    G++++WDK T + + L P + G+VCGLCGN +    +DF TR
Sbjct: 996  --YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATR 1053

Query: 992  YSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKV 1051
              SV    LEFGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  CH  V
Sbjct: 1054 SRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1113

Query: 1052 DPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA 1111
            +P+ Y++ C+ +ACACD  G    FCTAVA YA+AC  VG CV  R P++CP++CDYYN 
Sbjct: 1114 EPARYYEACVNDACACDSGGDCECFCTAVARYAQACHEVGTCVCLRTPSICPLFCDYYNP 1173

Query: 1112 PGECRWHYEPCGTVTAKTCKD 1132
             G+C WHY+PCG    +TC++
Sbjct: 1174 EGQCEWHYQPCGVPCLRTCRN 1194



 Score =  216 bits (550), Expect = 2e-55
 Identities = 113/330 (34%), Positives = 170/330 (51%), Gaps = 21/330 (6%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           + IF  S+ ++  +T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +
Sbjct: 527 VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRT 586

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T+ AF N+++  + CP    S      +S+E EK+A+  C  L D+ GP   C
Sbjct: 587 LSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRC 646

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SC 775
           H  V P  Y+  C   TC CE S+DCLC  L +YV ACA K   + GWR G+C     +C
Sbjct: 647 HAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 706

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P  + + Y+V  C  +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY
Sbjct: 707 PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCY 766

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDP---KAQ 889
               ++  G+ +H     C C  G L C   Q P  +    C+    + DC +       
Sbjct: 767 HRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTG 822

Query: 890 RRTNRTCSTRNIPVFDDQNI---VLQDGKV 916
               ++C T ++  +  Q +   V  DG V
Sbjct: 823 AGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 852



 Score =  134 bits (336), Expect = 1e-30
 Identities = 123/449 (27%), Positives = 175/449 (38%), Gaps = 54/449 (12%)

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCE 772
            + C  +V+   Y E C++  C CE++    C+C  L  Y + C         WR    C 
Sbjct: 278  SGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP 337

Query: 773  HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN--CVLKS 830
              CP+ + +      C  +C S  E  R+C  ED  V GC CP+    ++ G   CV  S
Sbjct: 338  QKCPNNMQYHECRSPCADTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVS 394

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-IPIDLTLQNCSG-------GAEYV- 881
            +C C  N     PG     D   C C  G   CQ +P   T     G       G +Y  
Sbjct: 395  KCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTV 454

Query: 882  --DCS----DPKAQRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESKKCELN 930
              DCS     P            R   + D +  +       DG  T V    S +  LN
Sbjct: 455  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLN 514

Query: 931  ----------ANAYSIHTVGLYLILKFQNGIIVIWD--KNTRLSVILDPNWNGKVCGLCG 978
                      AN         ++I +   G+ +        +L + L P   G+ CGLCG
Sbjct: 515  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCG 574

Query: 979  NNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF--PCDSNPYCKAWAVRKC 1036
            N N    DDF T    V + A  F N++KT   C + +  +F  PC  +   + +A   C
Sbjct: 575  NFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN-IRNSFEDPCSLSVENEKYAQHWC 633

Query: 1037 EILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV 1094
              L D+   F  CH  V P  Y+  C+ + C C+     L  C A++ Y  AC+A GV +
Sbjct: 634  SQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL--CAALSSYVHACAAKGVQL 691

Query: 1095 -SWR-----KP-NLCPVYCDYYNAPGECR 1116
              WR     KP   CP    Y+     C+
Sbjct: 692  GGWRDGVCTKPMTTCPKSMTYHYHVSTCQ 720



 Score = 85.1 bits (209), Expect = 7e-16
 Identities = 65/254 (25%), Positives = 113/254 (44%), Gaps = 29/254 (11%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----N 688
            +++++ P       GLCG++++ A +DF +    +      F NSW++  SCP      +
Sbjct: 1023 IFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKD 1082

Query: 689  PSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CL 745
            P +     K  +A++ C IL    GP  A+CH  V P  Y+E C    C C++  D  C 
Sbjct: 1083 PCTANPFRKS-WAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1138

Query: 746  CTILGNYVKACAEKETYIVGWRTGLCEHSC----PSGLVFKYNVKACNSSCRSLSERDRS 801
            CT +  Y +AC E  T +      +C   C    P G   +++ + C   C       R 
Sbjct: 1139 CTAVARYAQACHEVGTCVCLRTPSICPLFCDYYNPEGQC-EWHYQPCGVPCLRTCRNPRG 1197

Query: 802  CDVEDV-PVDGC--TCPD--AMYQNNEGNCVLKSQCD-----CYINDEVMQPGKLIHIDD 851
              + DV  ++GC   CP    ++  ++  CV           C+++ +  +PG ++  D 
Sbjct: 1198 DCLRDVRGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1257

Query: 852  N--KCVCRDGILLC 863
            N   C+C +  + C
Sbjct: 1258 NCQSCLCTERGVEC 1271



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 1032 AVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS-A 1089
            A+  CE +L    F  C   VD  +Y + C ++ C C+        C  +A Y+  C+ A
Sbjct: 264  ALASCEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHA 323

Query: 1090 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1133
             G+   WR P+ CP  C       ECR    PC    A TC +Q
Sbjct: 324  GGLPQDWRGPDFCPQKCPNNMQYHECR---SPC----ADTCSNQ 360



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)

Query: 496 IGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRS 554
           +G+Y E C +          +C   +C+  D  S  C T +E SR C   G G  + WR 
Sbjct: 286 VGSYLEACRQD---------LC---FCEDTDLLSCVCHTLAEYSRQCTHAG-GLPQDWRG 332

Query: 555 DSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ--DSECVSGCTCPEDKI 604
                C  Q+CP    Y EC      TCSN    +  +  CV+GC CPE  +
Sbjct: 333 PD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTV 381



>gi|51470790|ref|XP_039877.9|   PREDICTED: mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 4295

 Score =  265 bits (677), Expect = 4e-70
 Identities = 135/371 (36%), Positives = 190/371 (51%), Gaps = 44/371 (11%)

Query: 800  RSCDVEDVP------VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 853
            RSC   DV       V GC CP  +  +  G C+ +  C C  N+   +PG+ I +D N 
Sbjct: 852  RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNT 911

Query: 854  CVCRDGILLCQ----------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
            C CR+    C                 I  D    +  G  EY+   D      T+ T  
Sbjct: 912  CTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 971

Query: 898  --TRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGL 941
              T NIP                +   ++LQ+G   AV              Y I  +G+
Sbjct: 972  IVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPG-----GDPPYKIRYMGI 1026

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
            +L+++  +G+ V WD+ T + + L  ++ G+VCGLCGN + +  +DF TR  SV   ALE
Sbjct: 1027 FLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALE 1085

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCI 1061
            FGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  C ++VD + Y++ C+
Sbjct: 1086 FGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACV 1145

Query: 1062 EEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEP 1121
             +ACACD  G    FCTAVA YA+AC   G+CVSWR P+ CP++CD+YN  G C WHY+P
Sbjct: 1146 NDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQP 1205

Query: 1122 CGTVTAKTCKD 1132
            CG    KTC++
Sbjct: 1206 CGAPCLKTCRN 1216



 Score =  234 bits (597), Expect = 8e-61
 Identities = 119/315 (37%), Positives = 171/315 (54%), Gaps = 17/315 (5%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  SS ++ V+T   ++L +Q+VP+MQ++V + P       GLCG++N    DDF +
Sbjct: 551 ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA 610

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T  AFAN+W+  + C     S      +S+E E +A   C  L D +   + C
Sbjct: 611 LSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRC 670

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCE---HSC 775
           H I+NPKP+H  C   TC CE S+DCLC  L +YV ACA K   +  WR G+C     +C
Sbjct: 671 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 730

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P    + Y V AC  +CR LSE D +C V  VPVDGCTCP   + N+ G CV   +C CY
Sbjct: 731 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 790

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAE---YVDCSDPKA---Q 889
            +  V+ PG+++H +   C C  G L C   +  +LQ  +G A    Y+DCS+  A    
Sbjct: 791 AHGTVLAPGEVVHDEGAVCSCTGGKLSC---LGASLQKSTGCAAPMVYLDCSNSSAGTPG 847

Query: 890 RRTNRTCSTRNIPVF 904
               R+C T ++  F
Sbjct: 848 AECLRSCHTLDVGCF 862



 Score =  142 bits (357), Expect = 5e-33
 Identities = 138/533 (25%), Positives = 211/533 (39%), Gaps = 66/533 (12%)

Query: 636  VSMPPNQFTDTVGLCGSYNN-KAEDDFMSSQNI---LEKTSQAFANSWEM----MSCPKG 687
            + + P     T GLCG +N   A ++F +          T   F N  ++      CP  
Sbjct: 223  LELDPKYANQTCGLCGDFNGLPAFNEFYAHSECHLDARLTPLQFGNLQKLDGPTEQCPDP 282

Query: 688  NPSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
             P    +   E   E  C   L   GP  A CH +V+   Y   C +  C C     C C
Sbjct: 283  LPLPAGNCTDE---EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLCRCPT---CPC 334

Query: 747  TILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE 805
                 Y + CA        WR   LC  +CP  +  +     C  +C S  +R + C  E
Sbjct: 335  ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC-SNPQRAQLC--E 391

Query: 806  DVPVDGCTCPDAMYQNN--EGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
            D  VDGC CP     ++     C+   QC C        PG   +   + C C  G+  C
Sbjct: 392  DHCVDGCFCPPGTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQC 451

Query: 864  Q-IPIDLTLQNCSGGAE-----------YVDCSDPKAQRRTNRT----CSTRNIPVFDDQ 907
            Q +P   T  +  GGA            + DCS   +++  + +       R   + D++
Sbjct: 452  QDLPCPGTC-SVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNE 510

Query: 908  NIVLQ-----DGKVTAVKSTESKKCELN----------ANAYSIHTVGLYLILKFQNGII 952
            N +       DG  TA++        LN          AN         +++++   G+ 
Sbjct: 511  NCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQ 570

Query: 953  VIWDKNTRLSVI--LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ 1010
            ++      + V   LDP   G++CGLCGN N +  DDFT     V +    F N+WK   
Sbjct: 571  LLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA 630

Query: 1011 ECSDTVAQTF--PCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             C++    +F  PC  +   + +A   C  L D  S F  CH+ ++P  +H  C+ + C 
Sbjct: 631  ACAN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCN 689

Query: 1067 CDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHY 1119
            C+     L  C A++ Y  AC+A GV +S  +  +C  Y    N P   R+ Y
Sbjct: 690  CERSEDCL--CAALSSYVHACAAKGVQLSDWRDGVCTKYMQ--NCPKSQRYAY 738



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 22/207 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----NPSSCISIEKEKFAE 702
            GLCG++++ A +DF +    +   +  F NSW++  SCP      +P +     K  +A+
Sbjct: 1059 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKS-WAQ 1117

Query: 703  RHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEK 759
            + C IL    GP  A+C   V+   Y+E C    C C++  D  C CT +  Y +AC + 
Sbjct: 1118 KQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD- 1173

Query: 760  ETYIVGWRTG-----LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP-VDGC- 812
                V WRT       C+   P G   +++ + C + C           + D+P ++GC 
Sbjct: 1174 AGLCVSWRTPDTCPLFCDFYNPHG-GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1232

Query: 813  -TCPDAMYQNNEGNCVLKSQCDCYIND 838
              CP +    NE      +QC CY  D
Sbjct: 1233 PKCPPSQPFFNEDQMKCVAQCGCYDKD 1259



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 47/184 (25%), Positives = 70/184 (38%), Gaps = 27/184 (14%)

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSD----------TVAQTFPCD 1023
            CG C NN    +DD   R  + A+   +   +W       D          T +   P  
Sbjct: 3754 CGTCTNNQ---RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVS 3810

Query: 1024 SNPYCKAWAVRK-CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
            S P       +  C+++    F +CHN V P  + + CI + C     G+    C ++  
Sbjct: 3811 STPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEA 3866

Query: 1083 YAEACSAVGVCVSWR--KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YAE C A GVC  WR     LC + C            Y+PCG +   TC  +    +  
Sbjct: 3867 YAELCRARGVCSDWRGATGGLCDLTCPPTKV-------YKPCGPIQPATCNSRNQSPQLE 3919

Query: 1141 SLLE 1144
             + E
Sbjct: 3920 GMAE 3923



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 55/240 (22%), Positives = 93/240 (38%), Gaps = 29/240 (12%)

Query: 903  VFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLS 962
            V   Q +VL+    + + + + ++   +     +   G Y+ +  +  +  +W+      
Sbjct: 163  VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSAL 222

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA----LEFGNSWK---TSQECSDT 1015
            + LDP +  + CGLCG+ NG    +    +S     A    L+FGN  K    +++C D 
Sbjct: 223  LELDPKYANQTCGLCGDFNGLPAFNEFYAHSECHLDARLTPLQFGNLQKLDGPTEQCPDP 282

Query: 1016 VAQTFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            +        D    C          L    F +CH  VD +AY   C ++ C C      
Sbjct: 283  LPLPAGNCTDEEGICH-------RTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP-- 333

Query: 1074 LGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
               C     Y+  C+ A G   +WR P LCP  C            ++ CG+    TC +
Sbjct: 334  ---CATFVEYSRQCAHAGGQPRNWRCPELCPRTC-------PLNMQHQECGSPCTDTCSN 383



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 492  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
            C+ ++   F +C  +      +   CI ++C+ R +   C +    + LC + G      
Sbjct: 3824 CDLMLSQVFAECHNLVP-PGPFFNACISDHCRGRLEVP-CQSLEAYAELCRARG--VCSD 3879

Query: 552  WRSDSDVVCGTQRCPEQHIYKECGPSNPATCS--NVAPFQDSECVSGCTCPEDKIQIFNA 609
            WR  +  +C    CP   +YK CGP  PATC+  N +P Q      GC CPED+I +FNA
Sbjct: 3880 WRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPEDQI-LFNA 3936



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 70/290 (24%), Positives = 115/290 (39%), Gaps = 46/290 (15%)

Query: 645  DTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC------------PKGNPSSC 692
            +T G CG+  N   DD +        + +  A +W +               P  +P++ 
Sbjct: 3749 NTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAP 3808

Query: 693  ISIEKEKF---AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
            +S          +  C ++L  S   A CH +V P P+   C   +  C    +  C  L
Sbjct: 3809 VSSTPTPTPCPPQPLCDLML--SQVFAECHNLVPPGPFFNAC--ISDHCRGRLEVPCQSL 3864

Query: 750  GNYVKACAEKETYIVGWR---TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
              Y + C  +      WR    GLC+ +CP   V+K       ++C S   R++S  +E 
Sbjct: 3865 EAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 3920

Query: 807  VPVDGCTCPD--AMYQNNEGNCVLKSQCDCYINDEVMQ-PGKLIHIDDNKCVCRDGILLC 863
            +  +GC CP+   ++  + G CV    C C   D   + PG+    +   CVC +G +  
Sbjct: 3921 M-AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSV 3977

Query: 864  Q---IPIDLTLQ----NCSGGAEYVDCSDPKAQR----RTNRTCSTRNIP 902
            Q   +P D   Q    N  G   +V  + P+A+      T   C+T   P
Sbjct: 3978 QCKPLPCDAQGQPPPCNRPG---FVTVTRPRAENPCCPETVCVCNTTTCP 4024



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 44/131 (33%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 474 CPNAVGKSYEVC--EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           CP+ +      C  E+GI H   ++G  F +C  +   S  Y   C  + C  R  T  C
Sbjct: 279 CPDPLPLPAGNCTDEEGICH-RTLLGPAFAECHALVD-STAYLAACAQDLC--RCPTCPC 334

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV--APFQ 589
            T+ E SR CA  G G   +WR     +C  + CP    ++ECG     TCSN   A   
Sbjct: 335 ATFVEYSRQCAHAG-GQPRNWRCPE--LC-PRTCPLNMQHQECGSPCTDTCSNPQRAQLC 390

Query: 590 DSECVSGCTCP 600
           +  CV GC CP
Sbjct: 391 EDHCVDGCFCP 401



>gi|11275568|gb|AAG33673.1|   mucin 5B [Homo sapiens]
          Length = 1594

 Score =  265 bits (677), Expect = 4e-70
 Identities = 135/371 (36%), Positives = 190/371 (51%), Gaps = 44/371 (11%)

Query: 800  RSCDVEDVP------VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 853
            RSC   DV       V GC CP  +  +  G C+ +  C C  N+   +PG+ I +D N 
Sbjct: 818  RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNT 877

Query: 854  CVCRDGILLCQ----------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
            C CR+    C                 I  D    +  G  EY+   D      T+ T  
Sbjct: 878  CTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 937

Query: 898  --TRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGL 941
              T NIP                +   ++LQ+G   AV              Y I  +G+
Sbjct: 938  IVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPG-----GDPPYKIRYMGI 992

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
            +L+++  +G+ V WD+ T + + L  ++ G+VCGLCGN + +  +DF TR  SV   ALE
Sbjct: 993  FLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALE 1051

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCI 1061
            FGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  C ++VD + Y++ C+
Sbjct: 1052 FGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACV 1111

Query: 1062 EEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEP 1121
             +ACACD  G    FCTAVA YA+AC   G+CVSWR P+ CP++CD+YN  G C WHY+P
Sbjct: 1112 NDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQP 1171

Query: 1122 CGTVTAKTCKD 1132
            CG    KTC++
Sbjct: 1172 CGAPCLKTCRN 1182



 Score =  234 bits (597), Expect = 8e-61
 Identities = 119/315 (37%), Positives = 171/315 (54%), Gaps = 17/315 (5%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  SS ++ V+T   ++L +Q+VP+MQ++V + P       GLCG++N    DDF +
Sbjct: 517 ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA 576

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T  AFAN+W+  + C     S      +S+E E +A   C  L D +   + C
Sbjct: 577 LSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRC 636

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCE---HSC 775
           H I+NPKP+H  C   TC CE S+DCLC  L +YV ACA K   +  WR G+C     +C
Sbjct: 637 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 696

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P    + Y V AC  +CR LSE D +C V  VPVDGCTCP   + N+ G CV   +C CY
Sbjct: 697 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 756

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAE---YVDCSDPKA---Q 889
            +  V+ PG+++H +   C C  G L C   +  +LQ  +G A    Y+DCS+  A    
Sbjct: 757 AHGTVLAPGEVVHDEGAVCSCTGGKLSC---LGASLQKSTGCAAPMVYLDCSNSSAGTPG 813

Query: 890 RRTNRTCSTRNIPVF 904
               R+C T ++  F
Sbjct: 814 AECLRSCHTLDVGCF 828



 Score =  142 bits (358), Expect = 4e-33
 Identities = 139/531 (26%), Positives = 211/531 (39%), Gaps = 66/531 (12%)

Query: 636  VSMPPNQFTDTVGLCGSYNN-KAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGNPS 690
            + + P     T GLCG +N   A ++F +    L  T   F N  ++      CP   P 
Sbjct: 193  LELDPKYANQTCGLCGDFNGLPAFNEFYAHNARL--TPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 691  SCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
               +   E   E  C   L   GP  A CH +V+   Y   C +  C C     C C   
Sbjct: 251  PAGNCTDE---EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLCRCPT---CPCATF 302

Query: 750  GNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP 808
              Y + CA        WR   LC  +CP  +  +     C  +C S  +R + C  ED  
Sbjct: 303  VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC-SNPQRAQLC--EDHC 359

Query: 809  VDGCTCPDA---MYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ- 864
            VDGC CP     +       C+   QC C        PG   +   + C C  G+  CQ 
Sbjct: 360  VDGCFCPPGSTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQD 419

Query: 865  IPIDLTLQNCSGGAE-----------YVDCSDPKAQRRTNRT----CSTRNIPVFDDQNI 909
            +P   T  +  GGA            + DCS   +++  + +       R   + D++N 
Sbjct: 420  LPCPGTC-SVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENC 478

Query: 910  VLQ-----DGKVTAVKSTESKKCELN----------ANAYSIHTVGLYLILKFQNGIIVI 954
            +       DG  TA++        LN          AN         +++++   G+ ++
Sbjct: 479  LKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLL 538

Query: 955  WDKNTRLSVI--LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
                  + V   LDP   G++CGLCGN N +  DDFT     V +    F N+WK    C
Sbjct: 539  VQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAAC 598

Query: 1013 SDTVAQTF--PCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACD 1068
            ++    +F  PC  +   + +A   C  L D  S F  CH+ ++P  +H  C+ + C C+
Sbjct: 599  AN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCE 657

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHY 1119
                 L  C A++ Y  AC+A GV +S  +  +C  Y    N P   R+ Y
Sbjct: 658  RSEDCL--CAALSSYVHACAAKGVQLSDWRDGVCTKYMQ--NCPKSQRYAY 704



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 22/207 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----NPSSCISIEKEKFAE 702
            GLCG++++ A +DF +    +   +  F NSW++  SCP      +P +     K  +A+
Sbjct: 1025 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKS-WAQ 1083

Query: 703  RHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEK 759
            + C IL    GP  A+C   V+   Y+E C    C C++  D  C CT +  Y +AC + 
Sbjct: 1084 KQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD- 1139

Query: 760  ETYIVGWRTG-----LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP-VDGC- 812
                V WRT       C+   P G   +++ + C + C           + D+P ++GC 
Sbjct: 1140 AGLCVSWRTPDTCPLFCDFYNPHG-GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1198

Query: 813  -TCPDAMYQNNEGNCVLKSQCDCYIND 838
              CP +    NE      +QC CY  D
Sbjct: 1199 PKCPPSQPFFNEDQMKCVAQCGCYDKD 1225



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 56/237 (23%), Positives = 93/237 (39%), Gaps = 28/237 (11%)

Query: 903  VFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLS 962
            V   Q +VL+    + + + + ++   +     +   G Y+ +  +  +  +W+      
Sbjct: 133  VIKAQGLVLKASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSAL 192

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVAS-GALEFGNSWK---TSQECSDTVAQ 1018
            + LDP +  + CGLCG+ NG     F   Y+  A    L+FGN  K    +++C D +  
Sbjct: 193  LELDPKYANQTCGLCGDFNG--LPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 1019 TFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
                  D    C          L    F +CH  VD +AY   C ++ C C         
Sbjct: 251  PAGNCTDEEGICH-------RTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP----- 298

Query: 1077 CTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
            C     Y+  C+ A G   +WR P LCP  C            ++ CG+    TC +
Sbjct: 299  CATFVEYSRQCAHAGGQPRNWRCPELCPRTC-------PLNMQHQECGSPCTDTCSN 348



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 44/131 (33%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 474 CPNAVGKSYEVC--EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           CP+ +      C  E+GI H   ++G  F +C  +   S  Y   C  + C  R  T  C
Sbjct: 244 CPDPLPLPAGNCTDEEGICH-RTLLGPAFAECHALVD-STAYLAACAQDLC--RCPTCPC 299

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV--APFQ 589
            T+ E SR CA  G G   +WR     +C  + CP    ++ECG     TCSN   A   
Sbjct: 300 ATFVEYSRQCAHAG-GQPRNWRCPE--LC-PRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355

Query: 590 DSECVSGCTCP 600
           +  CV GC CP
Sbjct: 356 EDHCVDGCFCP 366



>gi|23821885|sp|Q9HC84|MU5B_HUMAN   Mucin 5B precursor (Mucin 5 subtype B, tracheobronchial) (High
            molecular weight salivary mucin MG1) (Sublingual gland
            mucin)
          Length = 5703

 Score =  265 bits (677), Expect = 4e-70
 Identities = 135/371 (36%), Positives = 190/371 (51%), Gaps = 44/371 (11%)

Query: 800  RSCDVEDVP------VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 853
            RSC   DV       V GC CP  +  +  G C+ +  C C  N+   +PG+ I +D N 
Sbjct: 818  RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNT 877

Query: 854  CVCRDGILLCQ----------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
            C CR+    C                 I  D    +  G  EY+   D      T+ T  
Sbjct: 878  CTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 937

Query: 898  --TRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGL 941
              T NIP                +   ++LQ+G   AV              Y I  +G+
Sbjct: 938  IVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPG-----GDPPYKIRYMGI 992

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
            +L+++  +G+ V WD+ T + + L  ++ G+VCGLCGN + +  +DF TR  SV   ALE
Sbjct: 993  FLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALE 1051

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCI 1061
            FGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  C ++VD + Y++ C+
Sbjct: 1052 FGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACV 1111

Query: 1062 EEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEP 1121
             +ACACD  G    FCTAVA YA+AC   G+CVSWR P+ CP++CD+YN  G C WHY+P
Sbjct: 1112 NDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPLFCDFYNPHGGCEWHYQP 1171

Query: 1122 CGTVTAKTCKD 1132
            CG    KTC++
Sbjct: 1172 CGAPCLKTCRN 1182



 Score =  234 bits (597), Expect = 8e-61
 Identities = 119/315 (37%), Positives = 171/315 (54%), Gaps = 17/315 (5%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  SS ++ V+T   ++L +Q+VP+MQ++V + P       GLCG++N    DDF +
Sbjct: 517 ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA 576

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T  AFAN+W+  + C     S      +S+E E +A   C  L D +   + C
Sbjct: 577 LSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRC 636

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCE---HSC 775
           H I+NPKP+H  C   TC CE S+DCLC  L +YV ACA K   +  WR G+C     +C
Sbjct: 637 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 696

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P    + Y V AC  +CR LSE D +C V  VPVDGCTCP   + N+ G CV   +C CY
Sbjct: 697 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 756

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAE---YVDCSDPKA---Q 889
            +  V+ PG+++H +   C C  G L C   +  +LQ  +G A    Y+DCS+  A    
Sbjct: 757 AHGTVLAPGEVVHDEGAVCSCTGGKLSC---LGASLQKSTGCAAPMVYLDCSNSSAGTPG 813

Query: 890 RRTNRTCSTRNIPVF 904
               R+C T ++  F
Sbjct: 814 AECLRSCHTLDVGCF 828



 Score =  142 bits (358), Expect = 4e-33
 Identities = 139/531 (26%), Positives = 211/531 (39%), Gaps = 66/531 (12%)

Query: 636  VSMPPNQFTDTVGLCGSYNN-KAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGNPS 690
            + + P     T GLCG +N   A ++F +    L  T   F N  ++      CP   P 
Sbjct: 193  LELDPKYANQTCGLCGDFNGLPAFNEFYAHNARL--TPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 691  SCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
               +   E   E  C   L   GP  A CH +V+   Y   C +  C C     C C   
Sbjct: 251  PAGNCTDE---EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLCRCPT---CPCATF 302

Query: 750  GNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP 808
              Y + CA        WR   LC  +CP  +  +     C  +C S  +R + C  ED  
Sbjct: 303  VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC-SNPQRAQLC--EDHC 359

Query: 809  VDGCTCPDA---MYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ- 864
            VDGC CP     +       C+   QC C        PG   +   + C C  G+  CQ 
Sbjct: 360  VDGCFCPPGSTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQD 419

Query: 865  IPIDLTLQNCSGGAE-----------YVDCSDPKAQRRTNRT----CSTRNIPVFDDQNI 909
            +P   T  +  GGA            + DCS   +++  + +       R   + D++N 
Sbjct: 420  LPCPGTC-SVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENC 478

Query: 910  VLQ-----DGKVTAVKSTESKKCELN----------ANAYSIHTVGLYLILKFQNGIIVI 954
            +       DG  TA++        LN          AN         +++++   G+ ++
Sbjct: 479  LKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLL 538

Query: 955  WDKNTRLSVI--LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
                  + V   LDP   G++CGLCGN N +  DDFT     V +    F N+WK    C
Sbjct: 539  VQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAAC 598

Query: 1013 SDTVAQTF--PCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACD 1068
            ++    +F  PC  +   + +A   C  L D  S F  CH+ ++P  +H  C+ + C C+
Sbjct: 599  AN-ARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCE 657

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHY 1119
                 L  C A++ Y  AC+A GV +S  +  +C  Y    N P   R+ Y
Sbjct: 658  RSEDCL--CAALSSYVHACAAKGVQLSDWRDGVCTKYMQ--NCPKSQRYAY 704



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 22/207 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----NPSSCISIEKEKFAE 702
            GLCG++++ A +DF +    +   +  F NSW++  SCP      +P +     K  +A+
Sbjct: 1025 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKS-WAQ 1083

Query: 703  RHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEK 759
            + C IL    GP  A+C   V+   Y+E C    C C++  D  C CT +  Y +AC + 
Sbjct: 1084 KQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD- 1139

Query: 760  ETYIVGWRTG-----LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP-VDGC- 812
                V WRT       C+   P G   +++ + C + C           + D+P ++GC 
Sbjct: 1140 AGLCVSWRTPDTCPLFCDFYNPHG-GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1198

Query: 813  -TCPDAMYQNNEGNCVLKSQCDCYIND 838
              CP +    NE      +QC CY  D
Sbjct: 1199 PKCPPSQPFFNEDQMKCVAQCGCYDKD 1225



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 47/184 (25%), Positives = 70/184 (38%), Gaps = 27/184 (14%)

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSD----------TVAQTFPCD 1023
            CG C NN    +DD   R  + A+   +   +W       D          T +   P  
Sbjct: 5162 CGTCTNNQ---RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVS 5218

Query: 1024 SNPYCKAWAVRK-CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
            S P       +  C+++    F +CHN V P  + + CI + C     G+    C ++  
Sbjct: 5219 STPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEA 5274

Query: 1083 YAEACSAVGVCVSWR--KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YAE C A GVC  WR     LC + C            Y+PCG +   TC  +    +  
Sbjct: 5275 YAELCRARGVCSDWRGATGGLCDLTCPPTKV-------YKPCGPIQPATCNSRNQSPQLE 5327

Query: 1141 SLLE 1144
             + E
Sbjct: 5328 GMAE 5331



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 56/237 (23%), Positives = 93/237 (39%), Gaps = 28/237 (11%)

Query: 903  VFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLS 962
            V   Q +VL+    + + + + ++   +     +   G Y+ +  +  +  +W+      
Sbjct: 133  VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSAL 192

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVAS-GALEFGNSWK---TSQECSDTVAQ 1018
            + LDP +  + CGLCG+ NG     F   Y+  A    L+FGN  K    +++C D +  
Sbjct: 193  LELDPKYANQTCGLCGDFNG--LPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 1019 TFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
                  D    C          L    F +CH  VD +AY   C ++ C C         
Sbjct: 251  PAGNCTDEEGICH-------RTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP----- 298

Query: 1077 CTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
            C     Y+  C+ A G   +WR P LCP  C            ++ CG+    TC +
Sbjct: 299  CATFVEYSRQCAHAGGQPRNWRCPELCPRTC-------PLNMQHQECGSPCTDTCSN 348



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 492  CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
            C+ ++   F +C  +      +   CI ++C+ R +   C +    + LC + G      
Sbjct: 5232 CDLMLSQVFAECHNLVP-PGPFFNACISDHCRGRLEVP-CQSLEAYAELCRARG--VCSD 5287

Query: 552  WRSDSDVVCGTQRCPEQHIYKECGPSNPATCS--NVAPFQDSECVSGCTCPEDKIQIFNA 609
            WR  +  +C    CP   +YK CGP  PATC+  N +P Q      GC CPED+I +FNA
Sbjct: 5288 WRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPEDQI-LFNA 5344



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 70/290 (24%), Positives = 115/290 (39%), Gaps = 46/290 (15%)

Query: 645  DTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC------------PKGNPSSC 692
            +T G CG+  N   DD +        + +  A +W +               P  +P++ 
Sbjct: 5157 NTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAP 5216

Query: 693  ISIEKEKF---AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
            +S          +  C ++L  S   A CH +V P P+   C   +  C    +  C  L
Sbjct: 5217 VSSTPTPTPCPPQPLCDLML--SQVFAECHNLVPPGPFFNAC--ISDHCRGRLEVPCQSL 5272

Query: 750  GNYVKACAEKETYIVGWR---TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
              Y + C  +      WR    GLC+ +CP   V+K       ++C S   R++S  +E 
Sbjct: 5273 EAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 5328

Query: 807  VPVDGCTCPD--AMYQNNEGNCVLKSQCDCYINDEVMQ-PGKLIHIDDNKCVCRDGILLC 863
            +  +GC CP+   ++  + G CV    C C   D   + PG+    +   CVC +G +  
Sbjct: 5329 M-AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSV 5385

Query: 864  Q---IPIDLTLQ----NCSGGAEYVDCSDPKAQR----RTNRTCSTRNIP 902
            Q   +P D   Q    N  G   +V  + P+A+      T   C+T   P
Sbjct: 5386 QCKPLPCDAQGQPPPCNRPG---FVTVTRPRAENPCCPETVCVCNTTTCP 5432



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 44/131 (33%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 474 CPNAVGKSYEVC--EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           CP+ +      C  E+GI H   ++G  F +C  +   S  Y   C  + C  R  T  C
Sbjct: 244 CPDPLPLPAGNCTDEEGICH-RTLLGPAFAECHALVD-STAYLAACAQDLC--RCPTCPC 299

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV--APFQ 589
            T+ E SR CA  G G   +WR     +C  + CP    ++ECG     TCSN   A   
Sbjct: 300 ATFVEYSRQCAHAG-GQPRNWRCPE--LC-PRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355

Query: 590 DSECVSGCTCP 600
           +  CV GC CP
Sbjct: 356 EDHCVDGCFCP 366



>gi|4038587|emb|CAA06167.1|   mucin [Homo sapiens]
          Length = 1283

 Score =  263 bits (672), Expect = 2e-69
 Identities = 134/371 (36%), Positives = 189/371 (50%), Gaps = 44/371 (11%)

Query: 800  RSCDVEDVP------VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 853
            RSC   DV       V GC CP  +  +  G C+ +  C C  N+   +PG+ I +D N 
Sbjct: 777  RSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNT 836

Query: 854  CVCRDGILLCQ----------------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
            C CR+    C                 I  D    +  G  EY+   D      T+ T  
Sbjct: 837  CTCRNRRWECSHGLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFR 896

Query: 898  --TRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGL 941
              T NIP                +   ++LQ+G   AV              Y I  +G+
Sbjct: 897  IVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVARGPG-----GDPPYKIRYMGI 951

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
            +L+++  +G+ V WD+ T + + L  ++ G+VCGLCGN + +  +DF TR  SV   ALE
Sbjct: 952  FLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALE 1010

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCI 1061
            FGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  C ++VD + Y++ C+
Sbjct: 1011 FGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACRSQVDSTKYYEACV 1070

Query: 1062 EEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEP 1121
             +ACACD  G    FCTAVA YA+AC   G+CV WR P+ CP++CD+YN  G C WHY+P
Sbjct: 1071 NDACACDSGGDCECFCTAVAAYAQACHDAGLCVCWRTPDTCPLFCDFYNPHGGCEWHYQP 1130

Query: 1122 CGTVTAKTCKD 1132
            CG    KTC++
Sbjct: 1131 CGAPCLKTCRN 1141



 Score =  230 bits (586), Expect = 1e-59
 Identities = 117/315 (37%), Positives = 172/315 (54%), Gaps = 18/315 (5%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  SS ++ V+T   ++L +Q+VP+MQ++V + P       GLCG++N    DDF +
Sbjct: 477 ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA 536

Query: 664 SQNILEKTSQAFANSWEMMSCPKGNPSS-----CISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T+  FAN+W+  +    + +S      +S+E E +A   C  L D +   + C
Sbjct: 537 LSGVVEATAH-FANTWKAQAACANSRNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRC 595

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCE---HSC 775
           H I+NPKP+H  C   TC CE S+DCLC  L +YV ACA K   +  WR G+C     +C
Sbjct: 596 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAPKGVQLSDWRDGVCTKYMQNC 655

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P    + Y V AC  +CR LSE D +C V  VPVDGCTCP   + N+ G CV   +C CY
Sbjct: 656 PKSQPYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCY 715

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAE---YVDCSDPKA---Q 889
            +  V+ PG+++H +   C C  G L C   +  +LQ  +G A    Y+DCS+  A    
Sbjct: 716 AHGTVLAPGEVVHDEGAVCSCTGGKLSC---LGASLQKSTGCAAPMVYLDCSNSSAGTPG 772

Query: 890 RRTNRTCSTRNIPVF 904
               R+C T ++  F
Sbjct: 773 AECLRSCHTLDVGCF 787



 Score =  139 bits (351), Expect = 3e-32
 Identities = 135/516 (26%), Positives = 207/516 (40%), Gaps = 64/516 (12%)

Query: 636  VSMPPNQFTDTVGLCGSYNN-KAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGNPS 690
            + + P     T GLCG +N   A ++F +    L  T   F N  ++      CP   P 
Sbjct: 154  LELDPKYANQTCGLCGDFNGLPAFNEFYAHNARL--TPLQFGNLQKLDGPTEQCPDPLPL 211

Query: 691  SCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
               +   E   E  C   L   GP  A CH +V+   Y   C +  C C     C C   
Sbjct: 212  PAGNCTDE---EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLCRCPT---CPCATF 263

Query: 750  GNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP 808
              Y + CA        WR   LC  +CP  +  +     C  +C S  +R + C  ED  
Sbjct: 264  VEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC-SNPQRAQLC--EDHC 320

Query: 809  VDGCTCPDAMYQNN--EGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-I 865
            VDGC CP     ++     C+   QC C        PG   +   + C C  G+  CQ +
Sbjct: 321  VDGCFCPPGTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDL 380

Query: 866  PIDLTLQNCSGGAE-----------YVDCSDPKAQRRTNRT----CSTRNIPVFDDQNIV 910
            P   T  +  GGA            + DCS   +++  + +       R   + D++N +
Sbjct: 381  PCPGTC-SVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNENCL 439

Query: 911  LQ-----DGKVTAVKSTESKKCELN----------ANAYSIHTVGLYLILKFQNGIIVIW 955
                   DG  TA++        LN          AN         +++++   G+ ++ 
Sbjct: 440  KAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLV 499

Query: 956  DKNTRLSVI--LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECS 1013
                 + V   LDP   G++CGLCGN N +  DDFT   S V      F N+WK    C+
Sbjct: 500  QLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA-LSGVVEATAHFANTWKAQAACA 558

Query: 1014 DTVAQTF--PCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDM 1069
            ++   +F  PC  +   + +A   C  L D  S F  CH+ ++P  +H  C+ + C C+ 
Sbjct: 559  NS-RNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCER 617

Query: 1070 EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVY 1105
                L  C A++ Y  AC+  GV +S  +  +C  Y
Sbjct: 618  SEDCL--CAALSSYVHACAPKGVQLSDWRDGVCTKY 651



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 59/207 (28%), Positives = 94/207 (45%), Gaps = 22/207 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----NPSSCISIEKEKFAE 702
            GLCG++++ A +DF +    +   +  F NSW++  SCP      +P +     K  +A+
Sbjct: 984  GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKS-WAQ 1042

Query: 703  RHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEK 759
            + C IL    GP  A+C   V+   Y+E C    C C++  D  C CT +  Y +AC + 
Sbjct: 1043 KQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD- 1098

Query: 760  ETYIVGWRTG-----LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP-VDGC- 812
                V WRT       C+   P G   +++ + C + C           + D+P ++GC 
Sbjct: 1099 AGLCVCWRTPDTCPLFCDFYNPHG-GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1157

Query: 813  -TCPDAMYQNNEGNCVLKSQCDCYIND 838
              CP +    NE      +QC CY  D
Sbjct: 1158 PKCPPSQPFFNEDQMKCVAQCGCYDKD 1184



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 56/237 (23%), Positives = 93/237 (39%), Gaps = 28/237 (11%)

Query: 903  VFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLS 962
            V   Q +VL+    + + + + ++   +     +   G Y+ +  +  +  +W+      
Sbjct: 94   VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSAL 153

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVAS-GALEFGNSWK---TSQECSDTVAQ 1018
            + LDP +  + CGLCG+ NG     F   Y+  A    L+FGN  K    +++C D +  
Sbjct: 154  LELDPKYANQTCGLCGDFNG--LPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPL 211

Query: 1019 TFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
                  D    C          L    F +CH  VD +AY   C ++ C C         
Sbjct: 212  PAGNCTDEEGICH-------RTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP----- 259

Query: 1077 CTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
            C     Y+  C+ A G   +WR P LCP  C            ++ CG+    TC +
Sbjct: 260  CATFVEYSRQCAHAGGQPRNWRCPELCPRTC-------PLNMQHQECGSPCTDTCSN 309



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 44/131 (33%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 474 CPNAVGKSYEVC--EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           CP+ +      C  E+GI H   ++G  F +C  +   S  Y   C  + C  R  T  C
Sbjct: 205 CPDPLPLPAGNCTDEEGICH-RTLLGPAFAECHALVD-STAYLAACAQDLC--RCPTCPC 260

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV--APFQ 589
            T+ E SR CA  G G   +WR     +C  + CP    ++ECG     TCSN   A   
Sbjct: 261 ATFVEYSRQCAHAG-GQPRNWRCPE--LC-PRTCPLNMQHQECGSPCTDTCSNPQRAQLC 316

Query: 590 DSECVSGCTCP 600
           +  CV GC CP
Sbjct: 317 EDHCVDGCFCP 327



>gi|7512452|pir||JE0095   gastric mucin MUC5AC precursor - human
          Length = 1373

 Score =  261 bits (666), Expect = 8e-69
 Identities = 136/381 (35%), Positives = 193/381 (50%), Gaps = 47/381 (12%)

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 847
            C  SC +L   D +C      V GC CPD +  + EG C+    C C  N+   + G+ I
Sbjct: 825  CQKSCHTL---DMTCYSPQC-VPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTI 880

Query: 848  HIDDNKCVCRDGILLCQIPIDLTLQNCS--GGAEYVD-----------------CSDPKA 888
             +  N C C   +  C    D  L  C+  G   Y+                  C    A
Sbjct: 881  RVGCNTCTCDSRMWRCTD--DPCLATCAVYGDGHYLTFDGQSYSFNEETASTRWCRTAVA 938

Query: 889  QRRTNRT---CSTRNIPV--------------FDDQNIVLQDGKVTAVKSTESKKCELNA 931
             +   RT    S R  P               + +  + L  GKV  + + ES++     
Sbjct: 939  GKTAPRTPFVLSPRTSPAAPQGPPAPRPSRFSWGNFELKLSHGKVEVIGTDESQEVP--- 995

Query: 932  NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 991
              Y+I  +G+YL++    G++++WDK T + + L P + G+VCGLCGN +    +DF TR
Sbjct: 996  --YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATR 1053

Query: 992  YSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKV 1051
              SV    LEFGNSWK S  C D +A   PC +NP+ K+WA ++C IL   TF  CH  V
Sbjct: 1054 SRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHV 1113

Query: 1052 DPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA 1111
            +P+ Y++ C+ +ACACD  G    FCTAVA YA+A   VG CV  R P++CP++CDYYN 
Sbjct: 1114 EPARYYEACVNDACACDSGGDCECFCTAVARYAQAGHEVGTCVCLRTPSICPLFCDYYNP 1173

Query: 1112 PGECRWHYEPCGTVTAKTCKD 1132
             G+C WHY+PCG    +TC++
Sbjct: 1174 EGQCEWHYQPCGVPCLRTCRN 1194



 Score =  216 bits (550), Expect = 2e-55
 Identities = 113/330 (34%), Positives = 170/330 (51%), Gaps = 21/330 (6%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           + IF  S+ ++  +T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +
Sbjct: 527 VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRT 586

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T+ AF N+++  + CP    S      +S+E EK+A+  C  L D+ GP   C
Sbjct: 587 LSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRC 646

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SC 775
           H  V P  Y+  C   TC CE S+DCLC  L +YV ACA K   + GWR G+C     +C
Sbjct: 647 HAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTC 706

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P  + + Y+V  C  +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY
Sbjct: 707 PKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCY 766

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDP---KAQ 889
               ++  G+ +H     C C  G L C   Q P  +    C+    + DC +       
Sbjct: 767 HRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPGDTG 822

Query: 890 RRTNRTCSTRNIPVFDDQNI---VLQDGKV 916
               ++C T ++  +  Q +   V  DG V
Sbjct: 823 AGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 852



 Score =  132 bits (333), Expect = 3e-30
 Identities = 123/449 (27%), Positives = 175/449 (38%), Gaps = 54/449 (12%)

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCE 772
            + C  +V+   Y E C++  C CE++    C+C  L  Y + C         WR    C 
Sbjct: 278  SGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP 337

Query: 773  HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN--CVLKS 830
              CP+ + +      C  +C S  E  R+C  ED  V GC CP+    ++ G   CV  S
Sbjct: 338  QKCPNNMQYHECRSPCADTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVS 394

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-IPIDLTLQNCSG-------GAEYV- 881
            +C C  N     PG     D   C C  G   CQ +P   T     G       G +Y  
Sbjct: 395  KCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPGPGTCSVLGGAHFSTFDGKQYTV 454

Query: 882  --DCS----DPKAQRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESKKCELN 930
              DCS     P            R   + D +  +       DG  T V    S +  LN
Sbjct: 455  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLN 514

Query: 931  ----------ANAYSIHTVGLYLILKFQNGIIVIWD--KNTRLSVILDPNWNGKVCGLCG 978
                      AN         ++I +   G+ +        +L + L P   G+ CGLCG
Sbjct: 515  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCG 574

Query: 979  NNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF--PCDSNPYCKAWAVRKC 1036
            N N    DDF T    V + A  F N++KT   C + +  +F  PC  +   + +A   C
Sbjct: 575  NFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN-IRNSFEDPCSLSVENEKYAQHWC 633

Query: 1037 EILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV 1094
              L D+   F  CH  V P  Y+  C+ + C C+     L  C A++ Y  AC+A GV +
Sbjct: 634  SQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL--CAALSSYVHACAAKGVQL 691

Query: 1095 -SWR-----KP-NLCPVYCDYYNAPGECR 1116
              WR     KP   CP    Y+     C+
Sbjct: 692  GGWRDGVCTKPMTTCPKSMTYHYHVSTCQ 720



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 64/254 (25%), Positives = 112/254 (44%), Gaps = 29/254 (11%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----N 688
            +++++ P       GLCG++++ A +DF +    +      F NSW++  SCP      +
Sbjct: 1023 IFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKD 1082

Query: 689  PSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CL 745
            P +     K  +A++ C IL    GP  A+CH  V P  Y+E C    C C++  D  C 
Sbjct: 1083 PCTANPFRKS-WAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 1138

Query: 746  CTILGNYVKACAEKETYIVGWRTGLCEHSC----PSGLVFKYNVKACNSSCRSLSERDRS 801
            CT +  Y +A  E  T +      +C   C    P G   +++ + C   C       R 
Sbjct: 1139 CTAVARYAQAGHEVGTCVCLRTPSICPLFCDYYNPEGQC-EWHYQPCGVPCLRTCRNPRG 1197

Query: 802  CDVEDV-PVDGC--TCPD--AMYQNNEGNCVLKSQCD-----CYINDEVMQPGKLIHIDD 851
              + DV  ++GC   CP    ++  ++  CV           C+++ +  +PG ++  D 
Sbjct: 1198 DCLRDVRGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 1257

Query: 852  N--KCVCRDGILLC 863
            N   C+C +  + C
Sbjct: 1258 NCQSCLCTERGVEC 1271



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 33/104 (31%), Positives = 46/104 (44%), Gaps = 9/104 (8%)

Query: 1032 AVRKCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS-A 1089
            A+  CE +L    F  C   VD  +Y + C ++ C C+        C  +A Y+  C+ A
Sbjct: 264  ALASCEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHA 323

Query: 1090 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1133
             G+   WR P+ CP  C       ECR    PC    A TC +Q
Sbjct: 324  GGLPQDWRGPDFCPQKCPNNMQYHECR---SPC----ADTCSNQ 360



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 19/112 (16%)

Query: 496 IGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRS 554
           +G+Y E C +          +C   +C+  D  S  C T +E SR C   G G  + WR 
Sbjct: 286 VGSYLEACRQD---------LC---FCEDTDLLSCVCHTLAEYSRQCTHAG-GLPQDWRG 332

Query: 555 DSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ--DSECVSGCTCPEDKI 604
                C  Q+CP    Y EC      TCSN    +  +  CV+GC CPE  +
Sbjct: 333 PD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCFCPEGTV 381



>gi|7513163|pir||JE0352   mucin MUC5B, tracheobronchial - human
 gi|3789927|gb|AAC67545.1|   mucin [Homo sapiens]
          Length = 1321

 Score =  259 bits (662), Expect = 2e-68
 Identities = 139/397 (35%), Positives = 199/397 (50%), Gaps = 48/397 (12%)

Query: 775  CPSGLVFKYNVKACNSSCRSL-SERDRSCDVEDVP------VDGCTCPDAMYQNNEGNCV 827
            C + +V+   +   NSS  +L +E D SC   DV       V GC CP  +  +  G C+
Sbjct: 793  CAAPMVY---LDCSNSSAGTLGAECDGSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 849

Query: 828  LKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ----------------IPIDLTL 871
             +  C C   +   + G+ I  D N C CR+    C                 I  D   
Sbjct: 850  AEEDCPCVNKEATYKLGETIRFDCNTCTCRNRTWECSHRLCLGTCVAYGDGHFITFDGDR 909

Query: 872  QNCSGGAEYVDCSDPKAQRRTNRTCS--TRNIPV--------------FDDQNIVLQDGK 915
             +  G  EY+   D      T+ T    T NIP                +   ++LQ+G 
Sbjct: 910  YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGT 969

Query: 916  VTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              AV              Y I  +G++L+++  +G+ V WD+ T + + L  ++  +VCG
Sbjct: 970  FKAVARGPG-----GDPPYKIRYMGIFLVIE-THGMAVSWDRKTSVFIRLHQDYKARVCG 1023

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRK 1035
            LCGN + +  +DF TR  SV   ALEFGNSWK S  C D +A   PC +NP+ K+WA ++
Sbjct: 1024 LCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAEKQ 1083

Query: 1036 CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS 1095
            C IL   TF  C ++VD + Y++ C+ +ACACD  G    FCTAVA YA+AC   G+CVS
Sbjct: 1084 CSILHGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS 1143

Query: 1096 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
            WR P+ CP++CD+YN  G C WHY+PCG    KTC++
Sbjct: 1144 WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRN 1180



 Score =  233 bits (594), Expect = 2e-60
 Identities = 116/296 (39%), Positives = 165/296 (55%), Gaps = 14/296 (4%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  SS ++ V+T   ++L +Q+VP+MQ++V + P       GLCG++N    DDF +
Sbjct: 515 ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTA 574

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T  AFAN+W+  + C     S      +S+E E +A   C  L  S+  L+ C
Sbjct: 575 LSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCSRLTRSNSALSRC 634

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCE---HSC 775
           H I+NPKP+H  C   TC CE S+DCLC  L +YV ACA K   +  WR G+C     +C
Sbjct: 635 HSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNC 694

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P    + Y V AC  +CR LSE D +C V  VPVDGCTCP   + N+ G CV   +C CY
Sbjct: 695 PKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQKCPCY 754

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAE---YVDCSDPKA 888
            +  V+ PG+++H +   C C  G L C   +  +LQ  +G A    Y+DCS+  A
Sbjct: 755 AHGTVLAPGEVVHDEGAVCSCTGGKLSC---LGASLQKSTGCAAPMVYLDCSNSSA 807



 Score =  128 bits (322), Expect = 6e-29
 Identities = 135/533 (25%), Positives = 206/533 (38%), Gaps = 72/533 (13%)

Query: 636  VSMPPNQFTDTVGLCGSYNN-KAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGNPS 690
            + + P     T GLCG +N   A ++F +    L  T   F N  ++      CP   P 
Sbjct: 193  LELDPKYANQTCGLCGDFNGLPAFNEFYAHNASL--TPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 691  SCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
               +   E   E  C   L   GP  A CH +V+   Y   C +  C C     C C   
Sbjct: 251  PAGNCTDE---EGICHRTL--LGPAFAECHALVDSTAYLAACAQDLCRCPT---CPCATF 302

Query: 750  GNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCR-SLSERDRSCDVEDVP 808
              Y + CA        WR   C   CP       + + C S C  + S   R+   +D  
Sbjct: 303  VEYSRQCAHAGGQPRNWR---CPELCPRTCTNMQH-QNCGSPCTDTCSNPQRAQLCKDHC 358

Query: 809  VDGCTCPDAMYQNN--EGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-I 865
            VD C CP     +N     C+   QC C        PG   +   + C C  G+  CQ +
Sbjct: 359  VDRCFCPPGTVLDNITHSGCLPLGQCPCTHGGTRYSPGTSFNTTCSSCTCSGGLWQCQDL 418

Query: 866  PIDLTLQNCSGGAEYVDCSDPK-------AQRRTNRTCSTRNIPVF---------DDQNI 909
            P   T  +  GGA ++   D K            ++ C+  +  V          D++N 
Sbjct: 419  PCPGTC-SVQGGA-HISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELGRCGLTDNENC 476

Query: 910  VLQ-----DGKVTAVKSTESKKCELN----------ANAYSIHTVGLYLILKFQNGIIVI 954
            +       DG  TA++        LN          AN         +++++   G+ ++
Sbjct: 477  LKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPPSAANITLFTPSSFFIVVQTGLGLQLL 536

Query: 955  WDKNTRLSVI--LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
                  + V   LDP   G++CGLCGN N +  DDFT     V +    F N+WK    C
Sbjct: 537  VQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAAC 596

Query: 1013 SDTVAQTF--PC----DSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACA 1066
            ++    +F  PC    ++  Y + W  R      +S    CH+ ++P  +H  C+ + C 
Sbjct: 597  AN-ARNSFEDPCSLSVENENYARHWCSRLTR--SNSALSRCHSIINPKPFHSNCMFDTCN 653

Query: 1067 CDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHY 1119
            C+     L  C A++ Y  AC+A GV +S  +  +C  Y    N P   R+ Y
Sbjct: 654  CERSEDCL--CAALSSYVHACAAKGVQLSDWRDGVCTKYMQ--NCPKSQRYAY 702



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 59/208 (28%), Positives = 96/208 (46%), Gaps = 25/208 (12%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----NPSSCISIEKEKFAE 702
            GLCG++++ A +DF +    +   +  F NSW++  SCP      +P +     K  +AE
Sbjct: 1023 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKS-WAE 1081

Query: 703  RHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEK 759
            + C IL    GP  A+C   V+   Y+E C    C C++  D  C CT +  Y +AC + 
Sbjct: 1082 KQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD- 1137

Query: 760  ETYIVGWRTG-----LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVP-VDGC- 812
                V WRT       C+   P G   +++ + C + C           + D+P ++ C 
Sbjct: 1138 AGLCVSWRTPDTCPLFCDFYNPHG-GCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLERCY 1196

Query: 813  -TCPDAM-YQNNEGNCVLKSQCDCYIND 838
              CP +  +  ++  CV  +QC CY  D
Sbjct: 1197 PKCPPSQPFNEDQMKCV--AQCGCYDKD 1222



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 62/248 (25%), Positives = 99/248 (39%), Gaps = 28/248 (11%)

Query: 903  VFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLS 962
            V   Q +VL+    + + + + ++   +     +   G Y+ +  +  +  +W+      
Sbjct: 133  VIKAQGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSAL 192

Query: 963  VILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVAS-GALEFGNSWK---TSQECSDTVAQ 1018
            + LDP +  + CGLCG+ NG     F   Y+  AS   L+FGN  K    +++C D +  
Sbjct: 193  LELDPKYANQTCGLCGDFNG--LPAFNEFYAHNASLTPLQFGNLQKLDGPTEQCPDPLPL 250

Query: 1019 TFP--CDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
                  D    C          L    F +CH  VD +AY   C ++ C C         
Sbjct: 251  PAGNCTDEEGICH-------RTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP----- 298

Query: 1077 CTAVAMYAEACS-AVGVCVSWRKPNLCPVYC---DYYNAPGECRWHYEPCGT-VTAKTCK 1131
            C     Y+  C+ A G   +WR P LCP  C    + N    C    + C     A+ CK
Sbjct: 299  CATFVEYSRQCAHAGGQPRNWRCPELCPRTCTNMQHQNCGSPCT---DTCSNPQRAQLCK 355

Query: 1132 DQLVGQKF 1139
            D  V + F
Sbjct: 356  DHCVDRCF 363



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 42/131 (32%), Positives = 54/131 (41%), Gaps = 13/131 (9%)

Query: 474 CPNAVGKSYEVC--EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           CP+ +      C  E+GI H   ++G  F +C  +   S  Y   C  + C  R  T  C
Sbjct: 244 CPDPLPLPAGNCTDEEGICH-RTLLGPAFAECHALVD-STAYLAACAQDLC--RCPTCPC 299

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV--APFQ 589
            T+ E SR CA  G G   +WR     +C       QH  + CG     TCSN   A   
Sbjct: 300 ATFVEYSRQCAHAG-GQPRNWRCPE--LCPRTCTNMQH--QNCGSPCTDTCSNPQRAQLC 354

Query: 590 DSECVSGCTCP 600
              CV  C CP
Sbjct: 355 KDHCVDRCFCP 365



>gi|4507907|ref|NP_000543.1|   von Willebrand factor precursor [Homo sapiens]
 gi|319923|pir||VWHU   von Willebrand factor precursor - human
 gi|340356|gb|AAB59458.1|   von Willebrand factor
 gi|401413|sp|P04275|VWF_HUMAN   Von Willebrand factor precursor (vWF) [Contains: Von Willebrand
            antigen II]
          Length = 2813

 Score =  250 bits (638), Expect = 1e-65
 Identities = 169/537 (31%), Positives = 245/537 (45%), Gaps = 55/537 (10%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNP-- 689
            V +    F  T GLCG++N  AEDDFM+ +  L      FANSW + S    C + +P  
Sbjct: 148  VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPS 207

Query: 690  SSC--ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
            SSC   S E +K     C  LL S+   A CHP+V+P+P+   C+K  C C    +C C 
Sbjct: 208  SSCNISSGEMQKGLWEQCQ-LLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACP 266

Query: 748  ILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             L  Y + CA++   + GW     C   CP+G+ ++  V  C  +C+SL   +     ++
Sbjct: 267  ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC---QE 323

Query: 807  VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC--- 863
              VDGC+CP+    + EG CV  ++C C  + +   PG  +  D N C+CR+   +C   
Sbjct: 324  RCVDGCSCPEGQLLD-EGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNE 382

Query: 864  QIP-------------IDLTLQNCSGGAEYV---DCSDPK-------AQRRTNR--TCS- 897
            + P              D      SG  +Y+   DC D          Q   +R   C+ 
Sbjct: 383  ECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTR 442

Query: 898  --TRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIW 955
              T  +P   +  + L+ G   A+   + +   L  +    HTV   + L +   + + W
Sbjct: 443  SVTVRLPGLHNSLVKLKHGAGVAMDGQDIQLPLLKGDLRIQHTVTASVRLSYGEDLQMDW 502

Query: 956  DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1015
            D   RL V L P + GK CGLCGN NG+  DDF T          +FGN+WK   +C D 
Sbjct: 503  DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDL 562

Query: 1016 VAQ-TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1074
              Q + PC  NP    ++   C +L   TF  CH  V P  Y   C  + C+C  +G+  
Sbjct: 563  QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCS-DGREC 621

Query: 1075 GFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
              C A+A YA AC+  GV V+WR+P  C + C            Y  CGT    TC+
Sbjct: 622  -LCGALASYAAACAGRGVRVAWREPGRCELNCPKGQV-------YLQCGTPCNLTCR 670



 Score =  181 bits (459), Expect = 8e-45
 Identities = 110/357 (30%), Positives = 162/357 (45%), Gaps = 37/357 (10%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 868
            V GC CP  M ++ E  CV   +C C+   +   PG+ + I  N CVCRD    C   + 
Sbjct: 805  VSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863

Query: 869  LTLQNCSGGAEYV-----------DC----------SDPKAQRRT--NRTCSTRNIPVFD 905
                +  G A Y+           +C          S+P   R    N+ CS  ++    
Sbjct: 864  DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNANA-YSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
               I+++ G++       + K  +     + +   G Y+IL     + V+WD++  +SV+
Sbjct: 924  RVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVV 983

Query: 965  LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDS 1024
            L   +  KVCGLCGN +G   +D T+    V    ++FGNSWK S +C+DT  +  P DS
Sbjct: 984  LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDS 1041

Query: 1025 NPYCKAWAVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFC 1077
            +P      + K       C IL    F+DC+  VDP  Y DVCI + C+C+  G    FC
Sbjct: 1042 SPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFC 1101

Query: 1078 TAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCK 1131
              +A YA  C+  G  V+WR   LCP  C+  N      EC W Y  C      TC+
Sbjct: 1102 DTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ 1158



 Score =  161 bits (408), Expect = 6e-39
 Identities = 78/236 (33%), Positives = 120/236 (50%), Gaps = 9/236 (3%)

Query: 633 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN 688
           +L V + P     T GLCG+YN    DDF++   + E   + F N+W++        K +
Sbjct: 507 RLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQH 566

Query: 689 PSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
              C ++    +F+E  C +L  +S    +CH  V+P PY   C+   C+C + ++CLC 
Sbjct: 567 SDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCG 624

Query: 748 ILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDV 807
            L +Y  ACA +   +     G CE +CP G V+      CN +CRSLS  D  C+  + 
Sbjct: 625 ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN--EA 682

Query: 808 PVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
            ++GC CP  +Y +  G+CV K+QC CY + E+ QP  +       C C DG + C
Sbjct: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHC 738



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 15/198 (7%)

Query: 940  GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 999
            G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+  ++ S  
Sbjct: 125  GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 184

Query: 1000 LEFGNSWKTS---QECSDTVAQTFPCD-SNPYCKAWAVRKCEILRD-STFRDCHNKVDPS 1054
             +F NSW  S   Q C      +  C+ S+   +     +C++L+  S F  CH  VDP 
Sbjct: 185  YDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPE 244

Query: 1055 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVG-VCVSWRKPNLCPVYCDYYNAPG 1113
             +  +C +  C C   G     C A+  YA  C+  G V   W   + C   C       
Sbjct: 245  PFVALCEKTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC------- 295

Query: 1114 ECRWHYEPCGTVTAKTCK 1131
                 Y  C +  A+TC+
Sbjct: 296  PAGMEYRQCVSPCARTCQ 313



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 35/253 (13%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPK-------GNPSSCIS-IEKE 698
            GLCG+++    +D  SS   +E+    F NSW++ S C          +P++C + I K+
Sbjct: 994  GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 1053

Query: 699  KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKAC 756
               +  C IL  +S     C+ +V+P+PY + C   TC+CE+  D  C C  +  Y   C
Sbjct: 1054 TMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111

Query: 757  AEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 809
            A+    +V WRT  LC  SC       +G   ++   +C  +C+   +           V
Sbjct: 1112 AQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV 1170

Query: 810  DGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGKLIHI---DDNKC-VCRDGIL 861
            +GC     P  +       CV    C  C +       GK + +   D   C +C     
Sbjct: 1171 EGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH---- 1226

Query: 862  LCQIPIDLTLQNC 874
             C + ++LT + C
Sbjct: 1227 -CDV-VNLTCEAC 1237



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 56/217 (25%), Positives = 88/217 (40%), Gaps = 26/217 (11%)

Query: 633  QLYVSMPPNQFTD-TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKG 687
            +  + + P  F   T GLCG  +    +DFM     +    +     W +     +C   
Sbjct: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126

Query: 688  NPSSCISIEKEKFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
                C+  +       HC +LL    PL A CH ++ P  ++  C++ +C     Q+ +C
Sbjct: 2127 LEEQCLVPDSS-----HCQVLLL---PLFAECHKVLAPATFYAICQQDSC----HQEQVC 2174

Query: 747  TILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE 805
             ++ +Y   C       V WRT   C  SCP  LV+ +    C   C        SC   
Sbjct: 2175 EVIASYAHLCRTNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG-- 2228

Query: 806  DVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQ 842
            D P +GC CP       EG+CV +  C   I ++ +Q
Sbjct: 2229 DHPSEGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQ 2264



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 46/189 (24%), Positives = 73/189 (38%), Gaps = 20/189 (10%)

Query: 951  IIVIWDKNTRLSVILDPN-WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            I     +N    + L P  +  K  GLCG  + +  +DF  R  +V +        W   
Sbjct: 2058 IFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ 2117

Query: 1010 QECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1069
            +       QT        C       C++L    F +CH  + P+ ++ +C +++C  + 
Sbjct: 2118 RP-----GQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ 2172

Query: 1070 EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYEP 1121
                   C  +A YA  C   GVCV WR P+ C + C     YN      P  C  +   
Sbjct: 2173 ------VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS 2226

Query: 1122 CGTVTAKTC 1130
            CG   ++ C
Sbjct: 2227 CGDHPSEGC 2235



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 30/116 (25%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 491  HCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE 550
            HC  ++   F +C KV A +  Y  IC  + C    +   C+  +  + LC ++G     
Sbjct: 2138 HCQVLLLPLFAECHKVLAPATFYA-ICQQDSCH---QEQVCEVIASYAHLCRTNG--VCV 2191

Query: 551  SWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEDKIQI 606
             WR+     C    CP   +Y  C    P  C             GC CP DK+ +
Sbjct: 2192 DWRTPD--FCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVML 2244



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 35/144 (24%), Positives = 55/144 (38%), Gaps = 19/144 (13%)

Query: 469 KIPGDCPNAVGKSYEVC-------EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEY 521
           K+ GDC +   +  + C           + C  +    FE C + A     Y   C  + 
Sbjct: 554 KLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR-AVSPLPYLRNCRYDV 612

Query: 522 CQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPA 580
           C   D +   C   +  +  CA  G G   +WR           CP+  +Y +CG     
Sbjct: 613 CSCSDGRECLCGALASYAAACA--GRGVRVAWREPGRCELN---CPKGQVYLQCGTPCNL 667

Query: 581 TCSNVAPFQDSE----CVSGCTCP 600
           TC +++ + D E    C+ GC CP
Sbjct: 668 TCRSLS-YPDEECNEACLEGCFCP 690



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 531 CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPF 588
           C    E +R CA +G   +  W   S   C    CP    Y++C      TC +  +   
Sbjct: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320

Query: 589 QDSECVSGCTCPEDKI 604
               CV GC+CPE ++
Sbjct: 321 CQERCVDGCSCPEGQL 336



>gi|37947|emb|CAA27972.1|   unnamed protein product [Homo sapiens]
          Length = 2813

 Score =  250 bits (638), Expect = 1e-65
 Identities = 169/537 (31%), Positives = 245/537 (45%), Gaps = 55/537 (10%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNP-- 689
            V +    F  T GLCG++N  AEDDFM+ +  L      FANSW + S    C + +P  
Sbjct: 148  VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPS 207

Query: 690  SSC--ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
            SSC   S E +K     C  LL S+   A CHP+V+P+P+   C+K  C C    +C C 
Sbjct: 208  SSCNISSGEMQKGLWEQCQ-LLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACP 266

Query: 748  ILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             L  Y + CA++   + GW     C   CP+G+ ++  V  C  +C+SL   +     ++
Sbjct: 267  ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC---QE 323

Query: 807  VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC--- 863
              VDGC+CP+    + EG CV  ++C C  + +   PG  +  D N C+CR+   +C   
Sbjct: 324  RCVDGCSCPEGQLLD-EGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNE 382

Query: 864  QIP-------------IDLTLQNCSGGAEYV---DCSDPK-------AQRRTNR--TCS- 897
            + P              D      SG  +Y+   DC D          Q   +R   C+ 
Sbjct: 383  ECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTR 442

Query: 898  --TRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIW 955
              T  +P   +  + L+ G   A+   + +   L  +    HTV   + L +   + + W
Sbjct: 443  SVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDW 502

Query: 956  DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1015
            D   RL V L P + GK CGLCGN NG+  DDF T          +FGN+WK   +C D 
Sbjct: 503  DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDL 562

Query: 1016 VAQ-TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1074
              Q + PC  NP    ++   C +L   TF  CH  V P  Y   C  + C+C  +G+  
Sbjct: 563  QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCS-DGREC 621

Query: 1075 GFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
              C A+A YA AC+  GV V+WR+P  C + C            Y  CGT    TC+
Sbjct: 622  -LCGALASYAAACAGRGVRVAWREPGRCELNCPKGQV-------YLQCGTPCNLTCR 670



 Score =  181 bits (459), Expect = 8e-45
 Identities = 110/357 (30%), Positives = 162/357 (45%), Gaps = 37/357 (10%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 868
            V GC CP  M ++ E  CV   +C C+   +   PG+ + I  N CVCRD    C   + 
Sbjct: 805  VSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863

Query: 869  LTLQNCSGGAEYV-----------DC----------SDPKAQRRT--NRTCSTRNIPVFD 905
                +  G A Y+           +C          S+P   R    N+ CS  ++    
Sbjct: 864  DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNANA-YSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
               I+++ G++       + K  +     + +   G Y+IL     + V+WD++  +SV+
Sbjct: 924  RVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVV 983

Query: 965  LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDS 1024
            L   +  KVCGLCGN +G   +D T+    V    ++FGNSWK S +C+DT  +  P DS
Sbjct: 984  LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDS 1041

Query: 1025 NPYCKAWAVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFC 1077
            +P      + K       C IL    F+DC+  VDP  Y DVCI + C+C+  G    FC
Sbjct: 1042 SPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFC 1101

Query: 1078 TAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCK 1131
              +A YA  C+  G  V+WR   LCP  C+  N      EC W Y  C      TC+
Sbjct: 1102 DTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ 1158



 Score =  161 bits (408), Expect = 6e-39
 Identities = 78/236 (33%), Positives = 120/236 (50%), Gaps = 9/236 (3%)

Query: 633 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN 688
           +L V + P     T GLCG+YN    DDF++   + E   + F N+W++        K +
Sbjct: 507 RLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQH 566

Query: 689 PSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
              C ++    +F+E  C +L  +S    +CH  V+P PY   C+   C+C + ++CLC 
Sbjct: 567 SDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCG 624

Query: 748 ILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDV 807
            L +Y  ACA +   +     G CE +CP G V+      CN +CRSLS  D  C+  + 
Sbjct: 625 ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN--EA 682

Query: 808 PVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
            ++GC CP  +Y +  G+CV K+QC CY + E+ QP  +       C C DG + C
Sbjct: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHC 738



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 15/198 (7%)

Query: 940  GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 999
            G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+  ++ S  
Sbjct: 125  GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 184

Query: 1000 LEFGNSWKTS---QECSDTVAQTFPCD-SNPYCKAWAVRKCEILRD-STFRDCHNKVDPS 1054
             +F NSW  S   Q C      +  C+ S+   +     +C++L+  S F  CH  VDP 
Sbjct: 185  YDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPE 244

Query: 1055 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVG-VCVSWRKPNLCPVYCDYYNAPG 1113
             +  +C +  C C   G     C A+  YA  C+  G V   W   + C   C       
Sbjct: 245  PFVALCEKTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC------- 295

Query: 1114 ECRWHYEPCGTVTAKTCK 1131
                 Y  C +  A+TC+
Sbjct: 296  PAGMEYRQCVSPCARTCQ 313



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 35/253 (13%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPK-------GNPSSCIS-IEKE 698
            GLCG+++    +D  SS   +E+    F NSW++ S C          +P++C + I K+
Sbjct: 994  GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 1053

Query: 699  KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKAC 756
               +  C IL  +S     C+ +V+P+PY + C   TC+CE+  D  C C  +  Y   C
Sbjct: 1054 TMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111

Query: 757  AEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 809
            A+    +V WRT  LC  SC       +G   ++   +C  +C+   +           V
Sbjct: 1112 AQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV 1170

Query: 810  DGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGKLIHI---DDNKC-VCRDGIL 861
            +GC     P  +       CV    C  C +       GK + +   D   C +C     
Sbjct: 1171 EGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH---- 1226

Query: 862  LCQIPIDLTLQNC 874
             C + ++LT + C
Sbjct: 1227 -CDV-VNLTCEAC 1237



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 56/217 (25%), Positives = 88/217 (40%), Gaps = 26/217 (11%)

Query: 633  QLYVSMPPNQFTD-TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKG 687
            +  + + P  F   T GLCG  +    +DFM     +    +     W +     +C   
Sbjct: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126

Query: 688  NPSSCISIEKEKFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
                C+  +       HC +LL    PL A CH ++ P  ++  C++ +C     Q+ +C
Sbjct: 2127 LEEQCLVPDSS-----HCQVLLL---PLFAECHKVLAPATFYAICQQDSC----HQEQVC 2174

Query: 747  TILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE 805
             ++ +Y   C       V WRT   C  SCP  LV+ +    C   C        SC   
Sbjct: 2175 EVIASYAHLCRTNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG-- 2228

Query: 806  DVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQ 842
            D P +GC CP       EG+CV +  C   I ++ +Q
Sbjct: 2229 DHPSEGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQ 2264



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 46/189 (24%), Positives = 73/189 (38%), Gaps = 20/189 (10%)

Query: 951  IIVIWDKNTRLSVILDPN-WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            I     +N    + L P  +  K  GLCG  + +  +DF  R  +V +        W   
Sbjct: 2058 IFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ 2117

Query: 1010 QECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1069
            +       QT        C       C++L    F +CH  + P+ ++ +C +++C  + 
Sbjct: 2118 RP-----GQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSCHQEQ 2172

Query: 1070 EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYEP 1121
                   C  +A YA  C   GVCV WR P+ C + C     YN      P  C  +   
Sbjct: 2173 ------VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS 2226

Query: 1122 CGTVTAKTC 1130
            CG   ++ C
Sbjct: 2227 CGDHPSEGC 2235



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 30/116 (25%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 491  HCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE 550
            HC  ++   F +C KV A +  Y  IC  + C    +   C+  +  + LC ++G     
Sbjct: 2138 HCQVLLLPLFAECHKVLAPATFYA-ICQQDSCH---QEQVCEVIASYAHLCRTNG--VCV 2191

Query: 551  SWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEDKIQI 606
             WR+     C    CP   +Y  C    P  C             GC CP DK+ +
Sbjct: 2192 DWRTPD--FCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVML 2244



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 35/144 (24%), Positives = 55/144 (38%), Gaps = 19/144 (13%)

Query: 469 KIPGDCPNAVGKSYEVC-------EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEY 521
           K+ GDC +   +  + C           + C  +    FE C + A     Y   C  + 
Sbjct: 554 KLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR-AVSPLPYLRNCRYDV 612

Query: 522 CQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPA 580
           C   D +   C   +  +  CA  G G   +WR           CP+  +Y +CG     
Sbjct: 613 CSCSDGRECLCGALASYAAACA--GRGVRVAWREPGRCELN---CPKGQVYLQCGTPCNL 667

Query: 581 TCSNVAPFQDSE----CVSGCTCP 600
           TC +++ + D E    C+ GC CP
Sbjct: 668 TCRSLS-YPDEECNEACLEGCFCP 690



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 531 CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPF 588
           C    E +R CA +G   +  W   S   C    CP    Y++C      TC +  +   
Sbjct: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320

Query: 589 QDSECVSGCTCPEDKI 604
               CV GC+CPE ++
Sbjct: 321 CQERCVDGCSCPEGQL 336



>gi|37942|emb|CAA27765.1|   unnamed protein product [Homo sapiens]
          Length = 1400

 Score =  247 bits (630), Expect = 1e-64
 Identities = 168/537 (31%), Positives = 244/537 (45%), Gaps = 55/537 (10%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNP-- 689
            V +    F  T GLCG++N  AEDDFM+ +  L      FANSW + S    C + +P  
Sbjct: 148  VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPS 207

Query: 690  SSC--ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
            SSC   S E +K     C  LL S+   A CHP+V+P+P+   C+K  C C    +C C 
Sbjct: 208  SSCNISSGEMQKGLWEQCQ-LLKSTSVFARCHPLVDPEPFVALCEKTLCECAGGLECACP 266

Query: 748  ILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             L  Y + CA++   + GW     C   CP+G+ ++  V  C  +C+SL   +     ++
Sbjct: 267  ALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC---QE 323

Query: 807  VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC--- 863
              VDGC+CP+    + EG CV  ++C C  + +   PG  +  D N C+CR+   +C   
Sbjct: 324  RCVDGCSCPEGQLLD-EGLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSNE 382

Query: 864  QIP-------------IDLTLQNCSGGAEYV---DCSDPK-------AQRRTNR--TCS- 897
            + P              D      SG  +Y+   DC D          Q   +R   C+ 
Sbjct: 383  ECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTR 442

Query: 898  --TRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIW 955
              T  +P   +  + L+ G   A+   + +   L  +     TV   + L +   + + W
Sbjct: 443  SVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQRTVTASVRLSYGEDLQMDW 502

Query: 956  DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1015
            D   RL V L P + GK CGLCGN NG+  DDF T          +FGN+WK   +C D 
Sbjct: 503  DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDL 562

Query: 1016 VAQ-TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYL 1074
              Q + PC  NP    ++   C +L   TF  CH  V P  Y   C  + C+C  +G+  
Sbjct: 563  QKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCSCS-DGREC 621

Query: 1075 GFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1131
              C A+A YA AC+  GV V+WR+P  C + C            Y  CGT    TC+
Sbjct: 622  -LCGALASYAAACAGRGVRVAWREPGRCELNCPKGQV-------YLQCGTPCNLTCR 670



 Score =  181 bits (459), Expect = 8e-45
 Identities = 110/357 (30%), Positives = 162/357 (45%), Gaps = 37/357 (10%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 868
            V GC CP  M ++ E  CV   +C C+   +   PG+ + I  N CVCRD    C   + 
Sbjct: 805  VSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 863

Query: 869  LTLQNCSGGAEYV-----------DC----------SDPKAQRRT--NRTCSTRNIPVFD 905
                +  G A Y+           +C          S+P   R    N+ CS  ++    
Sbjct: 864  DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 923

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNANA-YSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
               I+++ G++       + K  +     + +   G Y+IL     + V+WD++  +SV+
Sbjct: 924  RVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVV 983

Query: 965  LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDS 1024
            L   +  KVCGLCGN +G   +D T+    V    ++FGNSWK S +C+DT  +  P DS
Sbjct: 984  LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDS 1041

Query: 1025 NPYCKAWAVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFC 1077
            +P      + K       C IL    F+DC+  VDP  Y DVCI + C+C+  G    FC
Sbjct: 1042 SPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFC 1101

Query: 1078 TAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCK 1131
              +A YA  C+  G  V+WR   LCP  C+  N      EC W Y  C      TC+
Sbjct: 1102 DTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ 1158



 Score =  161 bits (408), Expect = 6e-39
 Identities = 78/236 (33%), Positives = 120/236 (50%), Gaps = 9/236 (3%)

Query: 633 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM----MSCPKGN 688
           +L V + P     T GLCG+YN    DDF++   + E   + F N+W++        K +
Sbjct: 507 RLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQH 566

Query: 689 PSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
              C ++    +F+E  C +L  +S    +CH  V+P PY   C+   C+C + ++CLC 
Sbjct: 567 SDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCG 624

Query: 748 ILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDV 807
            L +Y  ACA +   +     G CE +CP G V+      CN +CRSLS  D  C+  + 
Sbjct: 625 ALASYAAACAGRGVRVAWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECN--EA 682

Query: 808 PVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
            ++GC CP  +Y +  G+CV K+QC CY + E+ QP  +       C C DG + C
Sbjct: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHC 738



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 56/198 (28%), Positives = 83/198 (41%), Gaps = 15/198 (7%)

Query: 940  GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 999
            G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+  ++ S  
Sbjct: 125  GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 184

Query: 1000 LEFGNSWKTS---QECSDTVAQTFPCD-SNPYCKAWAVRKCEILRD-STFRDCHNKVDPS 1054
             +F NSW  S   Q C      +  C+ S+   +     +C++L+  S F  CH  VDP 
Sbjct: 185  YDFANSWALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPE 244

Query: 1055 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVG-VCVSWRKPNLCPVYCDYYNAPG 1113
             +  +C +  C C   G     C A+  YA  C+  G V   W   + C   C       
Sbjct: 245  PFVALCEKTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC------- 295

Query: 1114 ECRWHYEPCGTVTAKTCK 1131
                 Y  C +  A+TC+
Sbjct: 296  PAGMEYRQCVSPCARTCQ 313



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 35/253 (13%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPK-------GNPSSCIS-IEKE 698
            GLCG+++    +D  SS   +E+    F NSW++ S C          +P++C + I K+
Sbjct: 994  GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 1053

Query: 699  KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKAC 756
               +  C IL  +S     C+ +V+P+PY + C   TC+CE+  D  C C  +  Y   C
Sbjct: 1054 TMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111

Query: 757  AEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 809
            A+    +V WRT  LC  SC       +G   ++   +C  +C+   +           V
Sbjct: 1112 AQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV 1170

Query: 810  DGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGKLIHI---DDNKC-VCRDGIL 861
            +GC     P  +       CV    C  C +       GK + +   D   C +C     
Sbjct: 1171 EGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH---- 1226

Query: 862  LCQIPIDLTLQNC 874
             C + ++LT + C
Sbjct: 1227 -CDV-VNLTCEAC 1237



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 35/144 (24%), Positives = 55/144 (38%), Gaps = 19/144 (13%)

Query: 469 KIPGDCPNAVGKSYEVC-------EDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEY 521
           K+ GDC +   +  + C           + C  +    FE C + A     Y   C  + 
Sbjct: 554 KLHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHR-AVSPLPYLRNCRYDV 612

Query: 522 CQTRD-KTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPA 580
           C   D +   C   +  +  CA  G G   +WR           CP+  +Y +CG     
Sbjct: 613 CSCSDGRECLCGALASYAAACA--GRGVRVAWREPGRCELN---CPKGQVYLQCGTPCNL 667

Query: 581 TCSNVAPFQDSE----CVSGCTCP 600
           TC +++ + D E    C+ GC CP
Sbjct: 668 TCRSLS-YPDEECNEACLEGCFCP 690



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 6/76 (7%)

Query: 531 CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN--VAPF 588
           C    E +R CA +G   +  W   S   C    CP    Y++C      TC +  +   
Sbjct: 265 CPALLEYARTCAQEGMVLY-GWTDHS--ACSPV-CPAGMEYRQCVSPCARTCQSLHINEM 320

Query: 589 QDSECVSGCTCPEDKI 604
               CV GC+CPE ++
Sbjct: 321 CQERCVDGCSCPEGQL 336



>gi|1362802|pir||S56015   gastric mucin MUC5AC - human (fragment)
 gi|547517|emb|CAA57309.1|   gastric mucin [Homo sapiens]
 gi|1098035|prf||2115204A   mucin
          Length = 850

 Score =  220 bits (561), Expect = 1e-56
 Identities = 90/183 (49%), Positives = 122/183 (66%)

Query: 950  GIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            G++++WDK T + + L P + G+VCGLCGN +    +DF TR  SV    LEFGNSWK S
Sbjct: 5    GLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLS 64

Query: 1010 QECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1069
              C D +A   PC +NP+ K+WA ++C IL   TF  CH  V+P+ Y++ C+ +ACACD 
Sbjct: 65   PSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDS 124

Query: 1070 EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKT 1129
             G    FCTAVA YA+AC  VG CV  R P++CP++CDYYN  G+C WHY+PCG    +T
Sbjct: 125  GGDCECFCTAVARYAQACHEVGTCVCLRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT 184

Query: 1130 CKD 1132
            C++
Sbjct: 185  CRN 187



 Score = 85.1 bits (209), Expect = 7e-16
 Identities = 65/254 (25%), Positives = 113/254 (44%), Gaps = 29/254 (11%)

Query: 634 LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----N 688
           +++++ P       GLCG++++ A +DF +    +      F NSW++  SCP      +
Sbjct: 16  IFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKD 75

Query: 689 PSSCISIEKEKFAERHCGILLDSSGP-LASCHPIVNPKPYHEECKKYTCTCENSQD--CL 745
           P +     K  +A++ C IL    GP  A+CH  V P  Y+E C    C C++  D  C 
Sbjct: 76  PCTANPFRKS-WAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECF 131

Query: 746 CTILGNYVKACAEKETYIVGWRTGLCEHSC----PSGLVFKYNVKACNSSCRSLSERDRS 801
           CT +  Y +AC E  T +      +C   C    P G   +++ + C   C       R 
Sbjct: 132 CTAVARYAQACHEVGTCVCLRTPSICPLFCDYYNPEGQC-EWHYQPCGVPCLRTCRNPRG 190

Query: 802 CDVEDV-PVDGC--TCPD--AMYQNNEGNCVLKSQCD-----CYINDEVMQPGKLIHIDD 851
             + DV  ++GC   CP    ++  ++  CV           C+++ +  +PG ++  D 
Sbjct: 191 DCLRDVRGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPRCHVHGKSYRPGAVVPSDK 250

Query: 852 N--KCVCRDGILLC 863
           N   C+C +  + C
Sbjct: 251 NCQSCLCTERGVEC 264



>gi|34765003|gb|AAQ82434.1|   mucin glycoprotein [Homo sapiens]
          Length = 1569

 Score =  203 bits (516), Expect = 2e-51
 Identities = 132/435 (30%), Positives = 186/435 (42%), Gaps = 64/435 (14%)

Query: 735  TCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRS 794
            TC C N +      L  ++ +C   +T+           SC      K+   AC  +C+ 
Sbjct: 742  TCHCINGRLSCPQRLQMFLASCQAPKTF----------KSCSQSSENKFGA-ACAPTCQM 790

Query: 795  LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKC 854
            L+        +  P  GC C + +Y+N  G CV   +C C  +      G  +H D   C
Sbjct: 791  LATGVACVPTKCEP--GCVCAEGLYENAYGQCVPPEECPCEFSGVSYPGGAELHTDCRTC 848

Query: 855  VCRDGILLCQ----IPIDLTLQN-------------CSGGAEY--------VDCSDPKAQ 889
             C  G   CQ     P   TL                 G  EY        V+ S P  +
Sbjct: 849  SCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNYSQPTFK 908

Query: 890  RRTNR--------TCSTRNIPVF-DDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG 940
              T          TCS R I +F    ++VL D   T        +  +   A S+    
Sbjct: 909  ILTENVICGNSGVTCS-RAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLV--- 964

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            + + +  +  + +IW+++  + + +       +CGLCGN NG++KDDF TR   VAS  L
Sbjct: 965  VDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSEL 1024

Query: 1001 EFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC 1060
            E  NSWK S  C D    T PC  N + ++WA RKC ++   TF  CH+KV    Y++ C
Sbjct: 1025 ELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEAC 1084

Query: 1061 IEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA--------- 1111
            + +AC CD  G     C AVA YA+AC   GVCV WR P  CP+YC +YN          
Sbjct: 1085 VRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEY 1144

Query: 1112 ----PGECRWHYEPC 1122
                   C WHY+PC
Sbjct: 1145 QYTQEANCTWHYQPC 1159



 Score =  193 bits (491), Expect = 1e-48
 Identities = 101/289 (34%), Positives = 148/289 (51%), Gaps = 9/289 (3%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  +S++LQ+ T F ++L +Q+ P+ Q YV++ P     T GLCG++N    DDF +
Sbjct: 486 ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTT 545

Query: 664 SQNILEKTSQAFANSWEMMSCPKG-----NPSSCISIEKEKFAERHCGILLDSSGPLASC 718
           S  I E T+  F +SW   +CP       +P S   + K   AE HC +LL +      C
Sbjct: 546 SMGIAEGTASLFVDSWRAGNCPDALERETDPCSMSQLNKV-CAETHCSMLLRTGTVFERC 604

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCP 776
           H  VNP P ++ C    C  E +   +C  LG+YV AC+ +   + GWR+ +  C   C 
Sbjct: 605 HATVNPAPIYKRCMYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCT 664

Query: 777 SGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 836
               F YN +AC  +C SLS+R   C    VPVDGC CPD  Y N +G CV K+QC C +
Sbjct: 665 GNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL 724

Query: 837 ND-EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
              + +   +   I+   C C +G L C   + + L +C     +  CS
Sbjct: 725 EGYKFILAEQSTVINGITCHCINGRLSCPQRLQMFLASCQAPKTFKSCS 773



 Score =  110 bits (275), Expect = 2e-23
 Identities = 135/558 (24%), Positives = 217/558 (38%), Gaps = 79/558 (14%)

Query: 604  IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
            +QI     S   V     ++L++   P   L V +         GLCG+++ K  ++F+S
Sbjct: 130  LQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVS 189

Query: 664  SQN-ILEKTSQAFANSWE---MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
             +   LE    A     +    +   +  PS+ +   ++    R C  LL    P  S  
Sbjct: 190  EEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHV---RQAQHARGCTQLLTLVAPECS-- 244

Query: 720  PIVNPKPYHEECKKYTCTCENS--QDCLCTILGNYVKACAEKETYIVGWRTGLCE-HSCP 776
              V+ +P+   C+           Q+     L  Y + C+     +     GLC    CP
Sbjct: 245  --VSKEPFVLSCQADVAAAPQPGPQNSSYATLSEYSRQCSMVGQPVALRSPGLCSVGQCP 302

Query: 777  SGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN---CVLKSQCD 833
            +  V++    AC  +C   S  + SC        GC CP+    N+  N   CV  +QC 
Sbjct: 303  ANQVYQECGSACVKTC---SNSEHSCSSSCT--FGCFCPEGTDLNDLSNNHTCVPVTQCP 357

Query: 834  CYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG-----GAEYVDCSDPKA 888
            C ++  +  PG++       C C  G  +C      T + C G     G  +V   D + 
Sbjct: 358  CVLHGAMYAPGEVTIAACQTCRCTLGRWVC------TERPCPGHCSLEGGSFVTTFDARP 411

Query: 889  QRRTNRTCS-----TRNIP-------VFD--------------------DQNIVLQDGKV 916
             R  + TC+     +  +P       V+D                    D+ ++ QD  V
Sbjct: 412  YR-FHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVV 470

Query: 917  TAVKSTESKKCEL---NANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKV 973
            T   + E+K       N   +   +  L +   F   ++V      +  V + P + G+ 
Sbjct: 471  T--NNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQT 528

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTV-AQTFPCDSNPYCKAWA 1032
             GLCGN NGD  DDFTT        A  F +SW+    C D +  +T PC  +   K  A
Sbjct: 529  RGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAG-NCPDALERETDPCSMSQLNKVCA 587

Query: 1033 VRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAV 1090
               C +L    + F  CH  V+P+  +  C+ +  AC+ E  +   C A+  Y  ACS  
Sbjct: 588  ETHCSMLLRTGTVFERCHATVNPAPIYKRCMYQ--ACNYEETFPHICAALGDYVHACSLR 645

Query: 1091 GVCV-SWRKP-NLCPVYC 1106
            GV +  WR   + C + C
Sbjct: 646  GVLLWGWRSSVDNCTIPC 663



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 57/202 (28%), Positives = 90/202 (44%), Gaps = 21/202 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCPK----GNPSSCISIEKEKFAE 702
            GLCG++N   +DDF +    +  +     NSW E   C       +P S ++  +  +AE
Sbjct: 999  GLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCS-LNAFRRSWAE 1057

Query: 703  RHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEKE 760
            R C ++  +S   A+CH  V   PY+E C +  C C++  D  CLC  +  Y +AC +K 
Sbjct: 1058 RKCSVI--NSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1115

Query: 761  TYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC---PDA 817
               V WRT      CP    F YN    +        ++ +C     P   C C   P +
Sbjct: 1116 V-CVDWRT---PAFCPIYCGF-YNTHTQDGHGEYQYTQEANCTWHYQP---CLCPSQPQS 1167

Query: 818  MYQNNEGNCVLKSQCDCYINDE 839
            +  +N   C   SQ + + ++E
Sbjct: 1168 VPGSNIEGCYNCSQDEYFDHEE 1189



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 46/182 (25%), Positives = 74/182 (40%), Gaps = 15/182 (8%)

Query: 953  VIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
            V+W  ++ L V+++  + G++CGLCGN +G + ++F +          +F    K     
Sbjct: 152  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLE-PHKFAALQKLDDPG 210

Query: 1013 SDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGK 1072
                 Q  P  S    +A   R C  L      +C    +P      C  +  A    G 
Sbjct: 211  EICTFQDIP--STHVRQAQHARGCTQLLTLVAPECSVSKEPFVLS--CQADVAAAPQPGP 266

Query: 1073 YLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTC 1130
                   ++ Y+  CS VG  V+ R P LC V        G+C  +  Y+ CG+   KTC
Sbjct: 267  QNSSYATLSEYSRQCSMVGQPVALRSPGLCSV--------GQCPANQVYQECGSACVKTC 318

Query: 1131 KD 1132
             +
Sbjct: 319  SN 320



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 29/79 (36%), Positives = 38/79 (48%), Gaps = 4/79 (5%)

Query: 523 QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATC 582
           Q   + S+  T SE SR C+  G     + RS    +C   +CP   +Y+ECG +   TC
Sbjct: 263 QPGPQNSSYATLSEYSRQCSMVGQPV--ALRSPG--LCSVGQCPANQVYQECGSACVKTC 318

Query: 583 SNVAPFQDSECVSGCTCPE 601
           SN      S C  GC CPE
Sbjct: 319 SNSEHSCSSSCTFGCFCPE 337



>gi|51493054|ref|XP_290540.5|   PREDICTED: mucin 6, gastric [Homo sapiens]
          Length = 2458

 Score =  201 bits (512), Expect = 5e-51
 Identities = 130/435 (29%), Positives = 186/435 (42%), Gaps = 64/435 (14%)

Query: 735  TCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRS 794
            TC C N +         ++ +C   +T+           SC      K+   AC  +C+ 
Sbjct: 762  TCHCINGRLSCPQRPQMFLASCQAPKTF----------KSCSQSSENKFGA-ACAPTCQM 810

Query: 795  LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKC 854
            L+        +  P  GC C + +Y+N +G CV   +C C  +      G  +H D   C
Sbjct: 811  LATGVACVPTKCEP--GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTC 868

Query: 855  VCRDGILLCQ----IPIDLTLQN-------------CSGGAEYVDCSD--------PKAQ 889
             C  G   CQ     P   TL                 G  EY+  +D        P  +
Sbjct: 869  SCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFK 928

Query: 890  RRTNR--------TCSTRNIPVF-DDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVG 940
              T          TCS R I +F    ++VL D   T        +  +   A S+    
Sbjct: 929  ILTENVICGNSGVTCS-RAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLV--- 984

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            + + +  +  + +IW+++  + + +       +CGLCGN NG++KDDF TR   VAS  L
Sbjct: 985  VDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSEL 1044

Query: 1001 EFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC 1060
            E  NSWK S  C D    T PC  N + ++WA RKC ++   TF  CH+KV    Y++ C
Sbjct: 1045 ELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEAC 1104

Query: 1061 IEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA--------- 1111
            + +AC CD  G     C AVA YA+AC   GVCV WR P  CP+YC +YN          
Sbjct: 1105 VRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEY 1164

Query: 1112 ----PGECRWHYEPC 1122
                   C WHY+PC
Sbjct: 1165 QYTQEANCTWHYQPC 1179



 Score =  192 bits (489), Expect = 3e-48
 Identities = 101/289 (34%), Positives = 148/289 (51%), Gaps = 9/289 (3%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           I +F  +S++LQ+ T F ++L +Q+ P+ Q YV++ P     T GLCG++N    DDF +
Sbjct: 506 ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTT 565

Query: 664 SQNILEKTSQAFANSWEMMSCPKG-----NPSSCISIEKEKFAERHCGILLDSSGPLASC 718
           S  I E T+  F +SW   +CP       +P S   + K   AE HC +LL +      C
Sbjct: 566 SMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKV-CAETHCSMLLRTGTVFERC 624

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCP 776
           H  VNP P+++ C    C  E +   +C  LG+YV AC+ +   + GWR+ +  C   C 
Sbjct: 625 HATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCT 684

Query: 777 SGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYI 836
               F YN +AC  +C SLS+R   C    VPVDGC CPD  Y N +G CV K+QC C +
Sbjct: 685 GNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL 744

Query: 837 ND-EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
              + +   +   I+   C C +G L C     + L +C     +  CS
Sbjct: 745 EGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCS 793



 Score =  119 bits (297), Expect = 5e-26
 Identities = 136/558 (24%), Positives = 219/558 (39%), Gaps = 78/558 (13%)

Query: 604  IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
            +QI     S   V     ++L++   P   L V +         GLCG+++ K  ++F+S
Sbjct: 149  LQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVS 208

Query: 664  SQN-ILEKTSQAFANSWE---MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
             +   LE    A     +    +   +  PS+ +   ++    R C  LL    P  S  
Sbjct: 209  EEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHV---RQAQHARICTQLLTLVAPECS-- 263

Query: 720  PIVNPKPYHEECKKYTCTCENS--QDCLCTILGNYVKACAEKETYIVGWRT-GLCE-HSC 775
              V+ +P+   C+           Q+  C  L  Y + C+     +  WR+ GLC    C
Sbjct: 264  --VSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQC 321

Query: 776  PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN---CVLKSQC 832
            P+  V++    AC  +C   S    SC        GC CP+    N+  N   CV  +QC
Sbjct: 322  PANQVYQECGSACVKTC---SNPQHSCSSSCT--FGCFCPEGTVLNDLSNNHTCVPVTQC 376

Query: 833  DCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG-----GAEYVDCSDPK 887
             C ++  +  PG++       C C  G  +C      T + C G     G  +V   D +
Sbjct: 377  PCVLHGAMYAPGEVTIAACQTCRCTLGRWVC------TERPCPGHCSLEGGSFVTTFDAR 430

Query: 888  AQRRTNRTCS-----TRNIP-------VFD--------------------DQNIVLQDGK 915
              R  + TC+     +  +P       V+D                    D+ ++ QD  
Sbjct: 431  PYR-FHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEV 489

Query: 916  VTAVKSTESKKCEL---NANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
            VT   + E+K       N   +   +  L +   F   ++V      +  V + P + G+
Sbjct: 490  VT--NNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQ 547

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWA 1032
              GLCGN NGD  DDFTT        A  F +SW+     +    +T PC  +   K  A
Sbjct: 548  TRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKVCA 607

Query: 1033 VRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAV 1090
               C +L    + F  CH  V+P+ ++  C+ +  AC+ E  +   C A+  Y  ACS  
Sbjct: 608  ETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQ--ACNYEETFPHICAALGDYVHACSLR 665

Query: 1091 GVCV-SWRKP-NLCPVYC 1106
            GV +  WR   + C + C
Sbjct: 666  GVLLWGWRSSVDNCTIPC 683



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 57/202 (28%), Positives = 90/202 (44%), Gaps = 21/202 (10%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMMSCPK----GNPSSCISIEKEKFAE 702
            GLCG++N   +DDF +    +  +     NSW E   C       +P S ++  +  +AE
Sbjct: 1019 GLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCS-LNAFRRSWAE 1077

Query: 703  RHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKACAEKE 760
            R C ++  +S   A+CH  V   PY+E C +  C C++  D  CLC  +  Y +AC +K 
Sbjct: 1078 RKCSVI--NSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1135

Query: 761  TYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC---PDA 817
               V WRT      CP    F YN    +        ++ +C     P   C C   P +
Sbjct: 1136 V-CVDWRT---PAFCPIYCGF-YNTHTQDGHGEYQYTQEANCTWHYQP---CLCPSQPQS 1187

Query: 818  MYQNNEGNCVLKSQCDCYINDE 839
            +  +N   C   SQ + + ++E
Sbjct: 1188 VPGSNIEGCYNCSQDEYFDHEE 1209



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 48/183 (26%), Positives = 75/183 (40%), Gaps = 16/183 (8%)

Query: 953  VIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
            V+W  ++ L V+++  + G++CGLCGN +G + ++F +          +F    K     
Sbjct: 171  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLE-PHKFAALQKLDDPG 229

Query: 1013 SDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGK 1072
                 Q  P  S    +A   R C  L      +C    +P      C  +  A    G 
Sbjct: 230  EICTFQDIP--STHVRQAQHARICTQLLTLVAPECSVSKEPFVLS--CQADVAAAPQPGP 285

Query: 1073 YLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKT 1129
                C  ++ Y+  CS VG  V  WR P LC V        G+C  +  Y+ CG+   KT
Sbjct: 286  QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACVKT 337

Query: 1130 CKD 1132
            C +
Sbjct: 338  CSN 340



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 523 QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATC 582
           Q   + S+C T SE SR C+  G      WRS    +C   +CP   +Y+ECG +   TC
Sbjct: 282 QPGPQNSSCATLSEYSRQCSMVGQPV-RRWRSPG--LCSVGQCPANQVYQECGSACVKTC 338

Query: 583 SNVAPFQDSECVSGCTCPEDKI 604
           SN      S C  GC CPE  +
Sbjct: 339 SNPQHSCSSSCTFGCFCPEGTV 360



>gi|3123852|gb|AAC15950.1|   mucin [Homo sapiens]
          Length = 1104

 Score =  196 bits (497), Expect = 3e-49
 Identities = 107/330 (32%), Positives = 164/330 (49%), Gaps = 21/330 (6%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           + IF  S+ ++  +T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +
Sbjct: 525 VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRT 584

Query: 664 SQNILEKTSQAFANSWEMMS-CPKGNPS----SCISIEKEKFAERHCGILLDSSGPLASC 718
              ++E T+ AF N+++  + CP    S      +S+E EK+A+  C  L D+ GP   C
Sbjct: 585 LSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRC 644

Query: 719 HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEH---SC 775
           H  V P  Y+  C   TC CE S+DCL             K   + GWR G+C     +C
Sbjct: 645 HAAVKPGTYYSNCMFDTCNCERSEDCLVRRAVLLRARLCAKGVQLGGWRDGVCTKPMITC 704

Query: 776 PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCY 835
           P  + + Y+V AC  +CRSLSE D +C V  +PVDGC CP   + ++ G CV  S C CY
Sbjct: 705 PKSMTYHYHVSACQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCY 764

Query: 836 INDEVMQPGKLIHIDDNKCVCRDGILLC---QIPIDLTLQNCSGGAEYVDCSDPKAQ--- 889
               ++  G+ +H     C C  G L C   Q P  +    C+    + DC +   +   
Sbjct: 765 HRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPV----CAAPMVFFDCRNATPRGTG 820

Query: 890 RRTNRTCSTRNIPVFDDQNI---VLQDGKV 916
               ++C T ++  +  Q +   V  DG V
Sbjct: 821 AGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 850



 Score =  149 bits (377), Expect = 2e-35
 Identities = 94/309 (30%), Positives = 133/309 (43%), Gaps = 51/309 (16%)

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
            C ++ P G         C  SC +L   D +C      V GC CPD +  + EG C+   
Sbjct: 811  CRNATPRG-----TGAGCQKSCHTL---DMTCYSPQC-VPGCVCPDGLVADGEGGCITAE 861

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCS--GGAEYV------- 881
             C C  N    + G+ I +  N C C   +  C    D  L  C+  G   Y+       
Sbjct: 862  DCPCVHNKASYRAGQTIRVGCNTCTCDSRMWRC--TDDPCLATCAVYGDGHYLTFDGQSY 919

Query: 882  ----DCSDPKAQRR----------------------TNRTCSTRNIPVFDDQNIVLQDGK 915
                DC     Q                        T  TCS           + L   K
Sbjct: 920  SFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHRK 979

Query: 916  VTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
            V  + + ES++       Y+I  +G+YL++    G++++WDK T + + L P + G+VCG
Sbjct: 980  VEVIGTDESQEV-----PYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCG 1034

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRK 1035
            LCGN +    +DF TR  SV    LEFGNSWK S  C D +A   PC +NP+ K+WA ++
Sbjct: 1035 LCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQ 1094

Query: 1036 CEILRDSTF 1044
            C IL   TF
Sbjct: 1095 CSILHGPTF 1103



 Score =  125 bits (315), Expect = 4e-28
 Identities = 146/568 (25%), Positives = 208/568 (36%), Gaps = 75/568 (13%)

Query: 606  IFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
            +   SSSY +VE    + L         L + +       T GLCG +N       + S 
Sbjct: 169  LIQQSSSYTKVEARLGLVLMWNHDD--SLLLELDTKYANKTCGLCGDFNGMPVVRELLSH 226

Query: 666  NILEKTSQAFANSWEM----------MSCPKGNPSSCISIEKEKFAERHCGILLDSSGPL 715
            N  + T   F N  +M          +  P  N S+   I         C  LL      
Sbjct: 227  NT-KLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LF 275

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCE 772
            + C  +V+   Y E C++  C CE++    C+C  L  Y + C         WR    C 
Sbjct: 276  SGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP 335

Query: 773  HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN--CVLKS 830
              CP+ + +      C  +C S  E  R+C  ED  V GC CP+    ++ G   CV  S
Sbjct: 336  QKCPNNMQYHECRSPCADTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-IPIDLTLQNCSG-------GAEYV- 881
            +C C  N     PG     D   C C  G   CQ +P   T     G       G +Y  
Sbjct: 393  KCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTV 452

Query: 882  --DCS----DPKAQRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESKKCELN 930
              DCS     P            R   + D +  +       DG  T V    S +  LN
Sbjct: 453  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLN 512

Query: 931  ----------ANAYSIHTVGLYLILKFQNGIIVIWD--KNTRLSVILDPNWNGKVCGLCG 978
                      AN         ++I +   G+ +        +L + L P   G+ CGLCG
Sbjct: 513  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCG 572

Query: 979  NNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTF--PCDSNPYCKAWAVRKC 1036
            N N    DDF T    V + A  F N++KT   C + +  +F  PC  +   + +A   C
Sbjct: 573  NFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPN-IRNSFEDPCSLSVENEKYAQHWC 631

Query: 1037 EILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV 1094
              L D+   F  CH  V P  Y+  C+ + C C+     L    AV + A  C+      
Sbjct: 632  SQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL-VRRAVLLRARLCAKGVQLG 690

Query: 1095 SWR-----KPNL-CPVYCDYYNAPGECR 1116
             WR     KP + CP    Y+     C+
Sbjct: 691  GWRDGVCTKPMITCPKSMTYHYHVSACQ 718



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 24/264 (9%)

Query: 877  GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSI 936
            GA Y D +  + +R       T +  +     +V+Q  K + + +        + +   I
Sbjct: 112  GAAYEDFNI-QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLI 170

Query: 937  HTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNG-DLKDDFTTRYSSV 995
                 Y  ++ + G++++W+ +  L + LD  +  K CGLCG+ NG  +  +  +  + +
Sbjct: 171  QQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVRELLSHNTKL 230

Query: 996  ASGALEFGNSWK---TSQECSDTVAQTFPCDSNPY--CKAWAVRKCEILRDSTFRDCHNK 1050
                +EFGN  K    +++C D V +     S  +  C+       E+L    F  C   
Sbjct: 231  T--PMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGICE-------ELLHGQLFSGCVAL 281

Query: 1051 VDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYY 1109
            VD  +Y + C ++ C C+        C  +A Y+  C+ A G+   WR P+ CP  C   
Sbjct: 282  VDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNN 341

Query: 1110 NAPGECRWHYEPCGTVTAKTCKDQ 1133
                ECR    PC    A TC +Q
Sbjct: 342  MQYHECR---SPC----ADTCSNQ 358



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 11/137 (8%)

Query: 474 CPNAVGKSYEVCEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRDK---TS 529
           C + V +    C  G   C +++ G  F  C  +  + + Y   C  + C   D    + 
Sbjct: 248 CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGS-YLEACRQDLCFCEDTDLLSC 306

Query: 530 TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ 589
            C T +E SR C   G G  + WR      C  Q+CP    Y EC      TCSN    +
Sbjct: 307 VCHTLAEYSRQCTHAG-GLPQDWRGPD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSR 362

Query: 590 --DSECVSGCTCPEDKI 604
             +  CV+GC CPE  +
Sbjct: 363 ACEDHCVAGCFCPEGTV 379



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 6/80 (7%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM-SCPKG----N 688
            +++++ P       GLCG++++ A +DF +    +      F NSW++  SCP      +
Sbjct: 1020 IFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPKD 1079

Query: 689  PSSCISIEKEKFAERHCGIL 708
            P +     K  +A++ C IL
Sbjct: 1080 PCTANPFRK-SWAQKQCSIL 1098



>gi|51492791|ref|XP_379967.2|   PREDICTED: similar to SCO-spondin [Homo sapiens]
          Length = 6601

 Score =  189 bits (481), Expect = 2e-47
 Identities = 154/586 (26%), Positives = 236/586 (40%), Gaps = 102/586 (17%)

Query: 635  YVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNP-- 689
            Y+++ P       GLCG++    +DDF++    +E +  AFA+ +++     CP  +   
Sbjct: 716  YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL 775

Query: 690  -SSCIS-IEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
             S C +  ++  FAE  C IL   S     CH +V+ +P++  C    C C+   DCLC 
Sbjct: 776  LSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCP 833

Query: 748  ILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
            +L  Y + CA+ E     WR   LC   CP G  ++    AC   C     +   C    
Sbjct: 834  VLSAYARRCAQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCG----KPEDCGELG 888

Query: 807  VPVDGCTCPDAMYQNNEGNCVLKSQC-----------------DCYINDEVMQPGKLIHI 849
              V GC CP  +  + EG CV  S C                 +C   + V  PG  +  
Sbjct: 889  SCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRWELVYAPGACLLT 948

Query: 850  DDNK-------------CVCRDGILLCQ---IPIDLTLQNCSG------GAEYVDCS--- 884
             D+              CVC  G +L     +P DL     SG           DC+   
Sbjct: 949  CDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCV 1008

Query: 885  ------DPKAQRRTNRTCSTRNIP---VFDD---------QNIVLQDGKVTAVKSTESKK 926
                      QRR+ R C     P    FD          + +++++       S ++  
Sbjct: 1009 CRGRQWHCTGQRRSGR-CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLP 1067

Query: 927  CELNA----NAYSIHTVGLYL-ILKFQ----NGIIVIWDK----------NTRLSVILDP 967
            C  +      A ++   G  + +L+ +    NG+ V   K           TR+ V L P
Sbjct: 1068 CGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRTRVLVQLSP 1127

Query: 968  NWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPY 1027
             + G+V GLCG+ +GD  +D  +R   +   A    +SW+ S  C +      PC  N +
Sbjct: 1128 QFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTH 1187

Query: 1028 CKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEAC 1087
               WA  +C  L    F  CH +V P  +++ C+ +AC CD  G     C+A+A YA+ C
Sbjct: 1188 RAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADEC 1247

Query: 1088 SAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1133
            +  G  V WR   LC + C+           YE CG     TC +Q
Sbjct: 1248 ARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTCHEQ 1286



 Score =  120 bits (301), Expect = 2e-26
 Identities = 80/253 (31%), Positives = 107/253 (42%), Gaps = 30/253 (11%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-------- 687
           +S+    +  T GLCG YN   EDDFM     L   +  F NSW +     G        
Sbjct: 297 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVA 356

Query: 688 ----NPSSCISIEKEKF-----AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC 738
               +P   I  + E       A+  C  LL+  GP   CH  V+P  YHE C    C  
Sbjct: 357 QGCDSPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAG 414

Query: 739 -------ENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                  E  Q  +C    +YV+ACA +  +I   + G CE  CP G ++   V  C  S
Sbjct: 415 AMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPS 474

Query: 792 CRSLSE-RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID 850
           C ++ +  + SC  E   V GC CP  ++ N    CV  + C CY   +   PG  +   
Sbjct: 475 CEAVGQGEEESCREE--CVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQL 531

Query: 851 DNKCVCRDGILLC 863
            N CVCRDG   C
Sbjct: 532 CNPCVCRDGRWHC 544



 Score =  105 bits (261), Expect = 7e-22
 Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 13/239 (5%)

Query: 633  QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPKGN--P 689
            ++ V + P       GLCG ++  A +D  S Q +LE T++  A+SW +   CP+    P
Sbjct: 1120 RVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLP 1179

Query: 690  SSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLC 746
              C ++  +  +A   CG LL     L  CH  V P+ ++E C    C C++  D  CLC
Sbjct: 1180 HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCECLC 1237

Query: 747  TILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRSCDV 804
            + +  Y   CA +  + V WR+  LC   C  G V++     C  +C     E    C V
Sbjct: 1238 SAIATYADECA-RHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV 1296

Query: 805  EDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
                V+GC CP+    +  G C+  + C C        PG ++  D   C C++G   C
Sbjct: 1297 V-ACVEGCFCPEGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1353



 Score =  102 bits (253), Expect = 6e-21
 Identities = 69/251 (27%), Positives = 109/251 (43%), Gaps = 22/251 (8%)

Query: 907  QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILD 966
            + +++Q G V+       +      +  S+  +G +L+L    G++V  D+   +S+ +D
Sbjct: 241  EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVD 300

Query: 967  PNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSDTVAQTFPCD 1023
                G+  GLCG  NG  +DDF      +A  A  FGNSW+   +   C D V     CD
Sbjct: 301  HELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCD 360

Query: 1024 S----------NPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM---- 1069
            S            + +A A   C  L +  F  CH +V P+ YH+ C+   CA  M    
Sbjct: 361  SPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSG 420

Query: 1070 -EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD----YYNAPGECRWHYEPCGT 1124
             EG+    C   A Y +AC+   + + WRKP  C   C     Y +    C    E  G 
Sbjct: 421  QEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQ 480

Query: 1125 VTAKTCKDQLV 1135
               ++C+++ V
Sbjct: 481  GEEESCREECV 491



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 65/230 (28%), Positives = 98/230 (42%), Gaps = 13/230 (5%)

Query: 905  DDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
            +D +I L+D     V   +     + A   S+       +L    G  V+W  +  ++ I
Sbjct: 658  EDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYI 717

Query: 965  -LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE--C-SDTVAQTF 1020
             LDP    +V GLCG    + +DDF T    V +    F + ++ + +  C S+  A   
Sbjct: 718  TLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLS 777

Query: 1021 PCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            PC ++    A+A   C IL  S F++CH  VD   ++  C+   C CD     L  C  +
Sbjct: 778  PCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL--CPVL 835

Query: 1081 AMYAEACSAVGVCVSWRKPNLCPVYC----DYYNAPGECRWHY---EPCG 1123
            + YA  C+  G    WR   LCPV C    +Y      C  H    E CG
Sbjct: 836  SAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCG 885



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 38/89 (42%)

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
            C ++  SG +       C  +C  +S +            GC CP+     +EG CV   
Sbjct: 1886 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPR 1945

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
            QC C ++     PG+ I  D   C+C+DG
Sbjct: 1946 QCPCLVDGARYWPGQRIKADCQLCICQDG 1974



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 10/91 (10%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 834
            C  GLV       C  SC    + +RSC    V  +GC CP  +  ++   C+  S+C C
Sbjct: 2755 CQKGLV-----PPCPPSCLD-PKANRSCSGHCV--EGCRCPPGLLLHDT-RCLPLSECPC 2805

Query: 835  YINDEVMQPGKLIHIDD-NKCVCRDGILLCQ 864
             + +E+  PG    + + ++CVC  G LLCQ
Sbjct: 2806 LVGEELKWPGVSFLLGNCSQCVCEKGELLCQ 2836



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 3/94 (3%)

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
            CE  CP+G+        C   C  L E    C  + V   GC CP    +  +G CV   
Sbjct: 4160 CEAGCPAGMEVVTCANRCPRRCSDLQE-GIVCQDDQVCQKGCRCPKGSLE-QDGGCVPIG 4217

Query: 831  QCDCY-INDEVMQPGKLIHIDDNKCVCRDGILLC 863
             CDC         PG       N C C+ G L C
Sbjct: 4218 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSC 4251



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 14/139 (10%)

Query: 471  PGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYC---QTRDK 527
            PGD P+    +          C  ++   F  C         Y+  C+ + C      D 
Sbjct: 1175 PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEW-CLYDACGCDSGGDC 1233

Query: 528  TSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAP 587
               C   +  +  CA  G      WRS    +C  Q C    +Y+ CGP+ P TC    P
Sbjct: 1234 ECLCSAIATYADECARHGHHV--RWRSQE--LCSLQ-CEGGQVYEACGPTCPPTCHEQHP 1288

Query: 588  -----FQDSECVSGCTCPE 601
                  Q   CV GC CPE
Sbjct: 1289 EPGWHCQVVACVEGCFCPE 1307



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 11/123 (8%)

Query: 746  CTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKA------CNSSCRSLSERD 799
            C+ L      C    +      T  C   CP  ++F+   +       C   C +     
Sbjct: 2996 CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGI 3055

Query: 800  RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID--DNKCVCR 857
              C     P  GCTCP  ++ +N  +C+ +SQC C ++ ++   G +  +D  +N C C 
Sbjct: 3056 VECTGFCAP--GCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCCSCN 3112

Query: 858  DGI 860
             GI
Sbjct: 3113 VGI 3115



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 13/134 (9%)

Query: 734  YTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCR 793
            + CT   SQ  LC   G    AC +   + +      C+  C  G  F+   + C  SC 
Sbjct: 4696 HLCTAPLSQQRLCPDPG----ACPDSCQWSLWGPWSPCQVPCSGG--FRLRWRECPHSCA 4749

Query: 794  SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDE----VMQPGKLIHI 849
             L +R +       P  GC CP       +G CV  S C C +        + P + + +
Sbjct: 4750 DLWDRVQCLQGPCRP--GCRCPPGQLVQ-DGRCVPISSCRCGLPSANASWELAPAQAVQL 4806

Query: 850  DDNKCVCRDGILLC 863
            D   C C +  L+C
Sbjct: 4807 DCQNCTCVNESLVC 4820



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 15/102 (14%)

Query: 783  YNVKACNSSCRSLSERDRSCDV-EDVPV--DGCTCPDAMYQNNEGNCVLKSQCDCYINDE 839
            +   AC S C  L     S  + +D+P    GC CP  + +   G C+   +C+C+    
Sbjct: 4529 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQ-AGGCIPPEECNCWHTSA 4587

Query: 840  V-----MQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG 876
                  + PG  + +   +C CR G L C      T Q C G
Sbjct: 4588 AGAGMTLAPGDRLQLGCKECECRRGELHC------TSQGCQG 4623



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 472 GDCPNAVGKSYEVCEDGIQH-------CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQT 524
           G CP+        C    Q        C  +  + F++C ++      Y + C+   C  
Sbjct: 766 GRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY-LRCLAAVCGC 824

Query: 525 RDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
              +   C   S  +R CA +G      WR+ +  +C    CP    Y+EC P+    C 
Sbjct: 825 DPGSDCLCPVLSAYARRCAQEGASP--PWRNQT--LCPVM-CPGGQEYRECAPACGQHCG 879

Query: 584 NVAPFQD-SECVSGCTCP 600
                 +   CV+GC CP
Sbjct: 880 KPEDCGELGSCVAGCNCP 897



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 18/121 (14%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYC--------QTRDKTSTCDTYSELSRLCAS 543
           C++++   F +C    + + +Y   C+  YC        Q   + + C T++   + CA 
Sbjct: 383 CHQLLEGPFGQCHAQVSPA-EYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACAR 441

Query: 544 DGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTC 599
                   WR      C  + CP   +Y +C    P +C  V   ++     ECVSGC C
Sbjct: 442 RH--IHIRWRKPG--FC-ERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCEC 496

Query: 600 P 600
           P
Sbjct: 497 P 497



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 25/161 (15%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 834
            CP G V      +C   C  L  +  +  V++    GC CP     +N G CV  + C C
Sbjct: 4880 CPPGQVLSACATSCPCLCWHL--QPGAICVQEPCQPGCGCPGGQLLHN-GTCVPPTACPC 4936

Query: 835  YIND-------------EVMQPGKLIHIDDNKCVCRDG-----ILLCQIPIDLTLQNCSG 876
              +              + + PG ++  +  +CVC  G     ++ CQ  + L++  C+ 
Sbjct: 4937 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQGEMWLSMPCCTS 4996

Query: 877  GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVT 917
              +  DC+    Q   ++ C  R   V       L+ G V+
Sbjct: 4997 KVKARDCT----QYTQSQGCDARKWKVLSLPVRKLRSGGVS 5033



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 16/76 (21%), Positives = 28/76 (36%)

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 847
            C  +C  ++      +       GC C    +++  G CV +  C+C+       PG   
Sbjct: 5068 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEW 5127

Query: 848  HIDDNKCVCRDGILLC 863
                  C+C  G  +C
Sbjct: 5128 QEACESCLCLSGRPVC 5143



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 16/83 (19%)

Query: 538  SRLCASDG-PGTFESWRSDSDVVC--------GTQRCPEQHIYKECGPSN--PATCSNVA 586
            SR CA    PG     R+ S  VC            CP   +Y+EC P    P +C++V 
Sbjct: 3798 SRRCARPPCPGPARQSRTCSTQVCRGADVAAASEAGCPAGRLYRECQPGEGCPFSCAHVT 3857

Query: 587  P----FQDSECVSGCTCPEDKIQ 605
                 F +  C  GC CPE   Q
Sbjct: 3858 QQVGCFSEG-CEEGCHCPEGTFQ 3879



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 45/185 (24%), Positives = 65/185 (35%), Gaps = 50/185 (27%)

Query: 754  KACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-C 812
            + C E  T       G   H C          + C  SC+ LS     C    V     C
Sbjct: 3646 RPCQENSTQCTDCGGGQSLHPCG---------QPCPRSCQDLSPGS-VCQPGSVGCQPTC 3695

Query: 813  TCPDAMYQNNEGNCVLKSQCDC--------------------YINDEVMQPGKLIHIDDN 852
             CP     + +G CV  + C C                    + + E ++PG+++    +
Sbjct: 3696 GCPLGQL-SQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCD 3754

Query: 853  KCVCRDGILLCQIPIDL----------TLQNCS---GGAEYV---DCSDP--KAQRRTNR 894
             C C  GIL CQ   D             ++CS   GG E +    C+ P      R +R
Sbjct: 3755 NCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSR 3814

Query: 895  TCSTR 899
            TCST+
Sbjct: 3815 TCSTQ 3819



>gi|51466599|ref|XP_376720.2|   PREDICTED: KIAA0543 protein [Homo sapiens]
          Length = 6615

 Score =  189 bits (481), Expect = 2e-47
 Identities = 154/586 (26%), Positives = 236/586 (40%), Gaps = 102/586 (17%)

Query: 635  YVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNP-- 689
            Y+++ P       GLCG++    +DDF++    +E +  AFA+ +++     CP  +   
Sbjct: 723  YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL 782

Query: 690  -SSCIS-IEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
             S C +  ++  FAE  C IL   S     CH +V+ +P++  C    C C+   DCLC 
Sbjct: 783  LSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCP 840

Query: 748  ILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
            +L  Y + CA+ E     WR   LC   CP G  ++    AC   C     +   C    
Sbjct: 841  VLSAYARRCAQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCG----KPEDCGELG 895

Query: 807  VPVDGCTCPDAMYQNNEGNCVLKSQC-----------------DCYINDEVMQPGKLIHI 849
              V GC CP  +  + EG CV  S C                 +C   + V  PG  +  
Sbjct: 896  SCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRWELVYAPGACLLT 955

Query: 850  DDNK-------------CVCRDGILLCQ---IPIDLTLQNCSG------GAEYVDCS--- 884
             D+              CVC  G +L     +P DL     SG           DC+   
Sbjct: 956  CDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCV 1015

Query: 885  ------DPKAQRRTNRTCSTRNIP---VFDD---------QNIVLQDGKVTAVKSTESKK 926
                      QRR+ R C     P    FD          + +++++       S ++  
Sbjct: 1016 CRGRQWHCTGQRRSGR-CQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLP 1074

Query: 927  CELNA----NAYSIHTVGLYL-ILKFQ----NGIIVIWDK----------NTRLSVILDP 967
            C  +      A ++   G  + +L+ +    NG+ V   K           TR+ V L P
Sbjct: 1075 CGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRTRVLVQLSP 1134

Query: 968  NWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPY 1027
             + G+V GLCG+ +GD  +D  +R   +   A    +SW+ S  C +      PC  N +
Sbjct: 1135 QFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTH 1194

Query: 1028 CKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEAC 1087
               WA  +C  L    F  CH +V P  +++ C+ +AC CD  G     C+A+A YA+ C
Sbjct: 1195 RAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADEC 1254

Query: 1088 SAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1133
            +  G  V WR   LC + C+           YE CG     TC +Q
Sbjct: 1255 ARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTCHEQ 1293



 Score =  113 bits (283), Expect = 2e-24
 Identities = 78/260 (30%), Positives = 103/260 (39%), Gaps = 37/260 (14%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPK--------- 686
           +S+    +  T GLCG YN   EDDFM     L   +  F NSW +              
Sbjct: 297 ISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSEPSVGLPPRLS 356

Query: 687 -------GNPSSCISIEKEKFAERH--------CGILLDSSGPLASCHPIVNPKPYHEEC 731
                  G P     +        H        C  LL+  GP   CH  V+P  YHE C
Sbjct: 357 PQPQDVGGGPEGGALVLYADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEAC 414

Query: 732 KKYTCTC-------ENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYN 784
               C         E  Q  +C    +YV+ACA +  +I   + G CE  CP G ++   
Sbjct: 415 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDC 474

Query: 785 VKACNSSCRSLSE-RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP 843
           V  C  SC ++ +  + SC  E   V GC CP  ++ N    CV  + C CY   +   P
Sbjct: 475 VSLCPPSCEAVGQGEEESCREE--CVSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVP 531

Query: 844 GKLIHIDDNKCVCRDGILLC 863
           G  +    N CVCRDG   C
Sbjct: 532 GDTVRQLCNPCVCRDGRWHC 551



 Score =  105 bits (261), Expect = 7e-22
 Identities = 70/239 (29%), Positives = 108/239 (45%), Gaps = 13/239 (5%)

Query: 633  QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPKGN--P 689
            ++ V + P       GLCG ++  A +D  S Q +LE T++  A+SW +   CP+    P
Sbjct: 1127 RVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLP 1186

Query: 690  SSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLC 746
              C ++  +  +A   CG LL     L  CH  V P+ ++E C    C C++  D  CLC
Sbjct: 1187 HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCECLC 1244

Query: 747  TILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRSCDV 804
            + +  Y   CA +  + V WR+  LC   C  G V++     C  +C     E    C V
Sbjct: 1245 SAIATYADECA-RHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQV 1303

Query: 805  EDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLC 863
                V+GC CP+    +  G C+  + C C        PG ++  D   C C++G   C
Sbjct: 1304 V-ACVEGCFCPEGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1360



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 65/230 (28%), Positives = 98/230 (42%), Gaps = 13/230 (5%)

Query: 905  DDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
            +D +I L+D     V   +     + A   S+       +L    G  V+W  +  ++ I
Sbjct: 665  EDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYI 724

Query: 965  -LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE--C-SDTVAQTF 1020
             LDP    +V GLCG    + +DDF T    V +    F + ++ + +  C S+  A   
Sbjct: 725  TLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLS 784

Query: 1021 PCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            PC ++    A+A   C IL  S F++CH  VD   ++  C+   C CD     L  C  +
Sbjct: 785  PCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL--CPVL 842

Query: 1081 AMYAEACSAVGVCVSWRKPNLCPVYC----DYYNAPGECRWHY---EPCG 1123
            + YA  C+  G    WR   LCPV C    +Y      C  H    E CG
Sbjct: 843  SAYARRCAQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCG 892



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 68/258 (26%), Positives = 108/258 (41%), Gaps = 29/258 (11%)

Query: 907  QNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILD 966
            + +++Q G V+       +      +  S+  +G +L+L    G++V  D+   +S+ +D
Sbjct: 241  EEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVD 300

Query: 967  PNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT-------------SQECS 1013
                G+  GLCG  NG  +DDF      +A  A  FGNSW+              S +  
Sbjct: 301  HELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSEPSVGLPPRLSPQPQ 360

Query: 1014 DTV------AQTFPCDSNP-YCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACA 1066
            D        A     D  P + +A A   C  L +  F  CH +V P+ YH+ C+   CA
Sbjct: 361  DVGGGPEGGALVLYADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYCA 420

Query: 1067 CDM-----EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD----YYNAPGECRW 1117
              M     EG+    C   A Y +AC+   + + WRKP  C   C     Y +    C  
Sbjct: 421  GAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLCPP 480

Query: 1118 HYEPCGTVTAKTCKDQLV 1135
              E  G    ++C+++ V
Sbjct: 481  SCEAVGQGEEESCREECV 498



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 38/89 (42%)

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
            C ++  SG +       C  +C  +S +            GC CP+     +EG CV   
Sbjct: 1900 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPR 1959

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
            QC C ++     PG+ I  D   C+C+DG
Sbjct: 1960 QCPCLVDGARYWPGQRIKADCQLCICQDG 1988



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 10/91 (10%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 834
            C  GLV       C  SC    + +RSC    V  +GC CP  +  ++   C+  S+C C
Sbjct: 2769 CQKGLV-----PPCPPSCLD-PKANRSCSGHCV--EGCRCPPGLLLHDT-RCLPLSECPC 2819

Query: 835  YINDEVMQPGKLIHIDD-NKCVCRDGILLCQ 864
             + +E+  PG    + + ++CVC  G LLCQ
Sbjct: 2820 LVGEELKWPGVSFLLGNCSQCVCEKGELLCQ 2850



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 3/94 (3%)

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
            CE  CP+G+        C   C  L E    C  + V   GC CP    +  +G CV   
Sbjct: 4174 CEAGCPAGMEVVTCANRCPRRCSDLQE-GIVCQDDQVCQKGCRCPKGSLE-QDGGCVPIG 4231

Query: 831  QCDCY-INDEVMQPGKLIHIDDNKCVCRDGILLC 863
             CDC         PG       N C C+ G L C
Sbjct: 4232 HCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSC 4265



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 14/139 (10%)

Query: 471  PGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYC---QTRDK 527
            PGD P+    +          C  ++   F  C         Y+  C+ + C      D 
Sbjct: 1182 PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEW-CLYDACGCDSGGDC 1240

Query: 528  TSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAP 587
               C   +  +  CA  G      WRS    +C  Q C    +Y+ CGP+ P TC    P
Sbjct: 1241 ECLCSAIATYADECARHGHHV--RWRSQE--LCSLQ-CEGGQVYEACGPTCPPTCHEQHP 1295

Query: 588  -----FQDSECVSGCTCPE 601
                  Q   CV GC CPE
Sbjct: 1296 EPGWHCQVVACVEGCFCPE 1314



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 30/123 (24%), Positives = 50/123 (40%), Gaps = 11/123 (8%)

Query: 746  CTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKA------CNSSCRSLSERD 799
            C+ L      C    +      T  C   CP  ++F+   +       C   C +     
Sbjct: 3010 CSSLAPGDTTCPGPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGI 3069

Query: 800  RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID--DNKCVCR 857
              C     P  GCTCP  ++ +N  +C+ +SQC C ++ ++   G +  +D  +N C C 
Sbjct: 3070 VECTGFCAP--GCTCPPGLFLHN-ASCLPRSQCPCQLHGQLYASGAMARLDSCNNCCSCN 3126

Query: 858  DGI 860
             GI
Sbjct: 3127 VGI 3129



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 35/134 (26%), Positives = 52/134 (38%), Gaps = 13/134 (9%)

Query: 734  YTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCR 793
            + CT   SQ  LC   G    AC +   + +      C+  C  G  F+   + C  SC 
Sbjct: 4710 HLCTAPLSQQRLCPDPG----ACPDSCQWSLWGPWSPCQVPCSGG--FRLRWRECPHSCA 4763

Query: 794  SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDE----VMQPGKLIHI 849
             L +R +       P  GC CP       +G CV  S C C +        + P + + +
Sbjct: 4764 DLWDRVQCLQGPCRP--GCRCPPGQLVQ-DGRCVPISSCRCGLPSANASWELAPAQAVQL 4820

Query: 850  DDNKCVCRDGILLC 863
            D   C C +  L+C
Sbjct: 4821 DCQNCTCVNESLVC 4834



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 15/102 (14%)

Query: 783  YNVKACNSSCRSLSERDRSCDV-EDVPV--DGCTCPDAMYQNNEGNCVLKSQCDCYINDE 839
            +   AC S C  L     S  + +D+P    GC CP  + +   G C+   +C+C+    
Sbjct: 4543 FEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQ-AGGCIPPEECNCWHTSA 4601

Query: 840  V-----MQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG 876
                  + PG  + +   +C CR G L C      T Q C G
Sbjct: 4602 AGAGMTLAPGDRLQLGCKECECRRGELHC------TSQGCQG 4637



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 472 GDCPNAVGKSYEVCEDGIQH-------CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQT 524
           G CP+        C    Q        C  +  + F++C ++      Y + C+   C  
Sbjct: 773 GRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY-LRCLAAVCGC 831

Query: 525 RDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
              +   C   S  +R CA +G      WR+ +  +C    CP    Y+EC P+    C 
Sbjct: 832 DPGSDCLCPVLSAYARRCAQEGASP--PWRNQT--LCPVM-CPGGQEYRECAPACGQHCG 886

Query: 584 NVAPFQD-SECVSGCTCP 600
                 +   CV+GC CP
Sbjct: 887 KPEDCGELGSCVAGCNCP 904



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 30/121 (24%), Positives = 50/121 (41%), Gaps = 18/121 (14%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYC--------QTRDKTSTCDTYSELSRLCAS 543
           C++++   F +C    + + +Y   C+  YC        Q   + + C T++   + CA 
Sbjct: 390 CHQLLEGPFGQCHAQVSPA-EYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACAR 448

Query: 544 DGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTC 599
                   WR      C  + CP   +Y +C    P +C  V   ++     ECVSGC C
Sbjct: 449 RH--IHIRWRKPG--FC-ERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCEC 503

Query: 600 P 600
           P
Sbjct: 504 P 504



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 25/161 (15%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC 834
            CP G V      +C   C  L  +  +  V++    GC CP     +N G CV  + C C
Sbjct: 4894 CPPGQVLSACATSCPCLCWHL--QPGAICVQEPCQPGCGCPGGQLLHN-GTCVPPTACPC 4950

Query: 835  YIND-------------EVMQPGKLIHIDDNKCVCRDG-----ILLCQIPIDLTLQNCSG 876
              +              + + PG ++  +  +CVC  G     ++ CQ  + L++  C+ 
Sbjct: 4951 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQGEMWLSMPCCTS 5010

Query: 877  GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVT 917
              +  DC+    Q   ++ C  R   V       L+ G V+
Sbjct: 5011 KVKARDCT----QYTQSQGCDARKWKVLSLPVRKLRSGGVS 5047



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 16/76 (21%), Positives = 28/76 (36%)

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLI 847
            C  +C  ++      +       GC C    +++  G CV +  C+C+       PG   
Sbjct: 5082 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSEW 5141

Query: 848  HIDDNKCVCRDGILLC 863
                  C+C  G  +C
Sbjct: 5142 QEACESCLCLSGRPVC 5157



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 57/228 (25%)

Query: 713  GPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKA--CAEKETYIVGWRTGL 770
            GP + C   +        C +   T E  + C     GN+ ++  C E  T       G 
Sbjct: 3622 GPWSPCDMCLGQSHRSRACSRPP-TPEGGRPCP----GNHTQSRPCQENSTQCTDCGGGQ 3676

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCPDAMYQNNEGNCVLK 829
              H C          + C  SC+ LS     C    V     C CP     + +G CV  
Sbjct: 3677 SLHPCG---------QPCPRSCQDLSPGS-VCQPGSVGCQPTCGCPLGQL-SQDGLCVPP 3725

Query: 830  SQCDC--------------------YINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDL 869
            + C C                    + + E ++PG+++    + C C  GIL CQ   D 
Sbjct: 3726 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3785

Query: 870  ----------TLQNCS---GGAEYV---DCSDP--KAQRRTNRTCSTR 899
                        ++CS   GG E +    C+ P      R +RTCST+
Sbjct: 3786 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQ 3833



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 27/83 (32%), Positives = 34/83 (40%), Gaps = 16/83 (19%)

Query: 538  SRLCASDG-PGTFESWRSDSDVVC--------GTQRCPEQHIYKECGPSN--PATCSNVA 586
            SR CA    PG     R+ S  VC            CP   +Y+EC P    P +C++V 
Sbjct: 3812 SRRCARPPCPGPARQSRTCSTQVCRGADVAAASEAGCPAGRLYRECQPGEGCPFSCAHVT 3871

Query: 587  P----FQDSECVSGCTCPEDKIQ 605
                 F +  C  GC CPE   Q
Sbjct: 3872 QQVGCFSEG-CEEGCHCPEGTFQ 3893



>gi|340361|gb|AAB59512.1|   von Willebrand factor prepropeptide
          Length = 2074

 Score =  181 bits (459), Expect = 8e-45
 Identities = 110/357 (30%), Positives = 162/357 (45%), Gaps = 37/357 (10%)

Query: 809  VDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPID 868
            V GC CP  M ++ E  CV   +C C+   +   PG+ + I  N CVCRD    C   + 
Sbjct: 66   VSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVC 124

Query: 869  LTLQNCSGGAEYV-----------DC----------SDPKAQRRT--NRTCSTRNIPVFD 905
                +  G A Y+           +C          S+P   R    N+ CS  ++    
Sbjct: 125  DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVKCKK 184

Query: 906  DQNIVLQDGKVTAVKSTESKKCELNANA-YSIHTVGLYLILKFQNGIIVIWDKNTRLSVI 964
               I+++ G++       + K  +     + +   G Y+IL     + V+WD++  +SV+
Sbjct: 185  RVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVV 244

Query: 965  LDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDS 1024
            L   +  KVCGLCGN +G   +D T+    V    ++FGNSWK S +C+DT  +  P DS
Sbjct: 245  LKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDS 302

Query: 1025 NPYCKAWAVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFC 1077
            +P      + K       C IL    F+DC+  VDP  Y DVCI + C+C+  G    FC
Sbjct: 303  SPATCHNNIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFC 362

Query: 1078 TAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCK 1131
              +A YA  C+  G  V+WR   LCP  C+  N      EC W Y  C      TC+
Sbjct: 363  DTIAAYAHVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ 419



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 35/253 (13%)

Query: 648 GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPK-------GNPSSCIS-IEKE 698
           GLCG+++    +D  SS   +E+    F NSW++ S C          +P++C + I K+
Sbjct: 255 GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 314

Query: 699 KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKAC 756
              +  C IL  +S     C+ +V+P+PY + C   TC+CE+  D  C C  +  Y   C
Sbjct: 315 TMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 372

Query: 757 AEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 809
           A+    +V WRT  LC  SC       +G   ++   +C  +C+   +           V
Sbjct: 373 AQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV 431

Query: 810 DGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGKLIHI---DDNKC-VCRDGIL 861
           +GC     P  +       CV    C  C +       GK + +   D   C +C     
Sbjct: 432 EGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH---- 487

Query: 862 LCQIPIDLTLQNC 874
            C + ++LT + C
Sbjct: 488 -CDV-VNLTCEAC 498



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 55/217 (25%), Positives = 88/217 (40%), Gaps = 26/217 (11%)

Query: 633  QLYVSMPPNQFTD-TVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKG 687
            +  + + P  F   T GLCG  +    +DFM     +    +     W +     +C   
Sbjct: 1328 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 1387

Query: 688  NPSSCISIEKEKFAERHCGILLDSSGPL-ASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
                C+  +       HC +LL    PL A CH ++ P  ++  C++ +    + Q+ +C
Sbjct: 1388 LEEQCLVPDSS-----HCQVLLL---PLFAECHKVLAPATFYAICQQDS----SHQEQVC 1435

Query: 747  TILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVE 805
             ++ +Y   C       V WRT   C  SCP  LV+ +    C   C        SC   
Sbjct: 1436 EVIASYAHLCRTNGV-CVDWRTPDFCAMSCPPSLVYNHCEHGCPRHC---DGNVSSCG-- 1489

Query: 806  DVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQ 842
            D P +GC CP       EG+CV +  C   I ++ +Q
Sbjct: 1490 DHPSEGCFCPPDKVM-LEGSCVPEEACTQCIGEDGVQ 1525



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 45/189 (23%), Positives = 72/189 (38%), Gaps = 20/189 (10%)

Query: 951  IIVIWDKNTRLSVILDPN-WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            I     +N    + L P  +  K  GLCG  + +  +DF  R  +V +        W   
Sbjct: 1319 IFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQ 1378

Query: 1010 QECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDM 1069
            +       QT        C       C++L    F +CH  + P+ ++ +C +++   + 
Sbjct: 1379 RP-----GQTCQPILEEQCLVPDSSHCQVLLLPLFAECHKVLAPATFYAICQQDSSHQEQ 1433

Query: 1070 EGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCD---YYN-----APGECRWHYEP 1121
                   C  +A YA  C   GVCV WR P+ C + C     YN      P  C  +   
Sbjct: 1434 ------VCEVIASYAHLCRTNGVCVDWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNVSS 1487

Query: 1122 CGTVTAKTC 1130
            CG   ++ C
Sbjct: 1488 CGDHPSEGC 1496



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 29/116 (25%), Positives = 44/116 (37%), Gaps = 9/116 (7%)

Query: 491  HCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFE 550
            HC  ++   F +C KV A +  Y +   D   Q +     C+  +  + LC ++G     
Sbjct: 1399 HCQVLLLPLFAECHKVLAPATFYAICQQDSSHQEQ----VCEVIASYAHLCRTNG--VCV 1452

Query: 551  SWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTCPEDKIQI 606
             WR+     C    CP   +Y  C    P  C             GC CP DK+ +
Sbjct: 1453 DWRTPD--FCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVML 1505



>gi|4503681|ref|NP_003881.1|   Fc fragment of IgG binding protein [Homo sapiens]
 gi|1944352|dbj|BAA19526.1|   IgG Fc binding protein [Homo sapiens]
          Length = 5405

 Score =  162 bits (411), Expect = 3e-39
 Identities = 152/573 (26%), Positives = 227/573 (39%), Gaps = 84/573 (14%)

Query: 633  QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKG- 687
            QL +S+P        GLCG+YN    DDF++    L   +  FA+SW++      C  G 
Sbjct: 594  QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGC 653

Query: 688  --NPSSCISIEKEKF-AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDC 744
              N  +C   + + +  +R CG+L    GP A CH  ++P+P+ E+C    C     +  
Sbjct: 654  QNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS 713

Query: 745  LCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKA----CNSSCRSLSERD 799
            LC  L  Y +AC E    +  WR+   C  SCP+   ++    A    CN +    +   
Sbjct: 714  LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG 773

Query: 800  RSCDVED--------------VPVDGCTCPDAMYQNNEGNCV-----LKSQCDCY-INDE 839
            R C VE               VP   C C     Q   G  V      + +C C     +
Sbjct: 774  RPC-VEGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ 832

Query: 840  VMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVD----------------- 882
            V    K       +C  ++G+L C      T Q  SG   YV                  
Sbjct: 833  VTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQG-SGDPHYVSFDGRRFDFMGTCTYLLV 891

Query: 883  --CSDPKA----------QRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESK 925
              C    A          + R ++T S       + + + +       G+V      +  
Sbjct: 892  GSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYL 951

Query: 926  KCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLK 985
              +       +   G   +++   G+ V +D N R++  +  ++   +CGLCGN NGD  
Sbjct: 952  PFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPA 1011

Query: 986  DDFTTRYSSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD- 1041
            DD   R    A+ AL FGNSW  +T   C  T     P  DS    +  +  +C IL D 
Sbjct: 1012 DDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADP 1071

Query: 1042 -STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKP 1099
               FR+CH+K+DP      C+ + C   + G+    C A+A YA AC A G  V  WR  
Sbjct: 1072 KGPFRECHSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSE 1129

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
             LCP+ C  ++       HYE C      +C D
Sbjct: 1130 ELCPLSCPPHS-------HYEACSYGCPLSCGD 1155



 Score =  150 bits (380), Expect = 1e-35
 Identities = 140/557 (25%), Positives = 210/557 (37%), Gaps = 103/557 (18%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGNPSSCISIEKEKF 700
            GLCG+YN    DD         K        W++     C     K  PS C   ++E F
Sbjct: 4611 GLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESF 4662

Query: 701  AERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 759
                 CG++  + GPLA CH +V P  Y + C    C  +     LC  +  YV AC   
Sbjct: 4663 GGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 4722

Query: 760  ETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 818
               +  WR    C   CP+   ++    +C  SC SLS  +     E    +GC C DA 
Sbjct: 4723 GAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCESACREGCVC-DAG 4778

Query: 819  YQNNEGNCVLKSQCDC------YINDEVMQPGKLI----------HID---------DNK 853
            +  +   CV   QC C      Y   EV  PG             H+            +
Sbjct: 4779 FVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEE 4838

Query: 854  CVCRDGILLCQ---------------IPIDLTLQNCSGGAEYV--DCSDPKAQRRTNRTC 896
            C   DG+  C                I +D  + +  G   YV      PK         
Sbjct: 4839 CRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIV 4898

Query: 897  STRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHT-------VGLYLILKFQN 949
              +N      + +V   G+V ++   +    +  A A  +          G  ++L+   
Sbjct: 4899 LEKNAAGHLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK 4958

Query: 950  GIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK-- 1007
            G+ +++D +  L + +   + G++CGLCGN NG+  DDF     S AS    FG +W+  
Sbjct: 4959 GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVP 5018

Query: 1008 -TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPS 1054
             +S+ C +             +T P +SN          C  LR+    F  C   + PS
Sbjct: 5019 GSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQLRNPQGPFATCQAVLSPS 5070

Query: 1055 AYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPG 1113
             Y   C+ + CA   +G     C ++A Y  AC A GV V  WR  + CP++C  ++   
Sbjct: 5071 EYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS--- 5125

Query: 1114 ECRWHYEPCGTVTAKTC 1130
                HY  C      +C
Sbjct: 5126 ----HYSICTRTCQGSC 5138



 Score =  142 bits (358), Expect = 4e-33
 Identities = 143/571 (25%), Positives = 204/571 (35%), Gaps = 117/571 (20%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGNPSSCISIEKEKF 700
            GLCG+YN    DD         K        W++     C     K  PS C   ++E F
Sbjct: 3410 GLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESF 3461

Query: 701  AERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 759
                 CG++  + GPLA CH +V P  Y + C    C  +     LC  +  YV AC   
Sbjct: 3462 GGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 3521

Query: 760  ETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 818
               +  W R   C   CP+   ++    +C  SC SLS  +     E    +GC C DA 
Sbjct: 3522 GAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCESACREGCVC-DAG 3577

Query: 819  YQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRD-GILLCQ---------- 864
            +  +   CV   QC C  +D     G+  +     D+ C CR+ G + C+          
Sbjct: 3578 FVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETC 3637

Query: 865  ---------IPIDLTLQNCSGGAEYVDCSDPKAQRRTN------RTCSTR----NIPVFD 905
                     + +  T    SG   Y      +            +TC TR       V  
Sbjct: 3638 RPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVL- 3696

Query: 906  DQNIVLQDGKVTAVK-----------STESKKCELNANAYSIHTV-------------GL 941
             +N+   +G+V+  +             E ++ ++  N   +                G 
Sbjct: 3697 QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGS 3756

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             ++++   G+ V +D    + V +  N+   +CGLCGN NGD KDDF     S A  A E
Sbjct: 3757 DVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE 3816

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYC-------------------KAWAVRKCEILRDS 1042
            FGNSW       + V    PC   P C                   K      C +L   
Sbjct: 3817 FGNSW-------EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSP 3869

Query: 1043 T--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKP 1099
            T     CH  VDP      CI + C     G     C+ +  Y  AC A G  V  WR  
Sbjct: 3870 TGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNE 3927

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
              CP+ C   +       HYE C    +  C
Sbjct: 3928 TFCPMECPQNS-------HYELCADTCSLGC 3951



 Score =  142 bits (358), Expect = 4e-33
 Identities = 143/571 (25%), Positives = 204/571 (35%), Gaps = 117/571 (20%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGNPSSCISIEKEKF 700
            GLCG+YN    DD         K        W++     C     K  PS C   ++E F
Sbjct: 2209 GLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESF 2260

Query: 701  AERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 759
                 CG++  + GPLA CH +V P  Y + C    C  +     LC  +  YV AC   
Sbjct: 2261 GGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320

Query: 760  ETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 818
               +  W R   C   CP+   ++    +C  SC SLS  +     E    +GC C DA 
Sbjct: 2321 GAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCESACREGCVC-DAG 2376

Query: 819  YQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRD-GILLCQ---------- 864
            +  +   CV   QC C  +D     G+  +     D+ C CR+ G + C+          
Sbjct: 2377 FVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETC 2436

Query: 865  ---------IPIDLTLQNCSGGAEYVDCSDPKAQRRTN------RTCSTR----NIPVFD 905
                     + +  T    SG   Y      +            +TC TR       V  
Sbjct: 2437 RPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVL- 2495

Query: 906  DQNIVLQDGKVTAVK-----------STESKKCELNANAYSIHTV-------------GL 941
             +N+   +G+V+  +             E ++ ++  N   +                G 
Sbjct: 2496 QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGS 2555

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             ++++   G+ V +D    + V +  N+   +CGLCGN NGD KDDF     S A  A E
Sbjct: 2556 DVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE 2615

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYC-------------------KAWAVRKCEILRDS 1042
            FGNSW       + V    PC   P C                   K      C +L   
Sbjct: 2616 FGNSW-------EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSP 2668

Query: 1043 T--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKP 1099
            T     CH  VDP      CI + C     G     C+ +  Y  AC A G  V  WR  
Sbjct: 2669 TGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNE 2726

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
              CP+ C   +       HYE C    +  C
Sbjct: 2727 TFCPMECPQNS-------HYELCADTCSLGC 2750



 Score =  139 bits (349), Expect = 4e-32
 Identities = 141/573 (24%), Positives = 213/573 (37%), Gaps = 97/573 (16%)

Query: 640  PNQFTDTV-GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNPSSCISI 695
            P+ + + + GLCG++N    DD           + AF NSW+  +   C    P  C  +
Sbjct: 992  PSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL 1051

Query: 696  E----KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGN 751
            +    ++  ++  CGIL D  GP   CH  ++P+    +C    C        LC  L  
Sbjct: 1052 DSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALAT 1111

Query: 752  YVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVD 810
            Y  AC      +  WR+  LC  SCP    ++     C  SC  L      C  E    +
Sbjct: 1112 YAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHE 1168

Query: 811  GCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL----- 862
            GC C +    + E +C+  + C C        PG+  +     D+ C C++G L+     
Sbjct: 1169 GCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227

Query: 863  -------CQ--------IPIDLTLQNCSGGAEYVDCSDPKAQRRTN------RTCSTR-- 899
                   CQ        + +  +    SG   Y      +            +TC TR  
Sbjct: 1228 SCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPG 1287

Query: 900  --NIPVFDDQNIVLQDGKVTAVK-----------STESKKCELNANAYSIHTV------- 939
                 V   +N+   +G+V+  +             E ++ ++  N   +          
Sbjct: 1288 LHRFAVL-QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQ 1346

Query: 940  ------GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYS 993
                  G  ++++   G+ V +D    + V +  N+  ++CGLCGN NGD KDDF     
Sbjct: 1347 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNG 1406

Query: 994  SVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK------CEILR 1040
            S A  A EFGNSW+     S  +  T PC     D  P   C     +K      C +L 
Sbjct: 1407 SQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465

Query: 1041 DST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WR 1097
              T     CH  VDP      CI + C     G     C+ +  Y  AC A G  V  WR
Sbjct: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWR 1523

Query: 1098 KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
                CP+ C   +       HYE C    +  C
Sbjct: 1524 TETFCPMECPPNS-------HYELCADTCSLGC 1549



 Score =  131 bits (329), Expect = 9e-30
 Identities = 145/614 (23%), Positives = 227/614 (36%), Gaps = 112/614 (18%)

Query: 601  EDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 660
            + +I +   +S  L V  +    LQ+      ++ V++P +      GLCG+ +    +D
Sbjct: 1769 DGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNND 1825

Query: 661  FMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSS 712
             +     L  +   +  SW        C      SC +  +++  +      CG L   +
Sbjct: 1826 QVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT 1885

Query: 713  G-PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL- 770
            G P  +CH  V P+ + + C    C     +D LC  L +YV AC      I  WR  + 
Sbjct: 1886 GGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG 1945

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LK 829
            CE +CP    ++     C +SC S +        E   V+GC C DA +  +   CV L 
Sbjct: 1946 CEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLN 2004

Query: 830  SQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
            + C C+ N    + G     D       +C    G L+C      T  +C  G     C 
Sbjct: 2005 NGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC------TPASCGLGEV---CG 2055

Query: 885  DPKAQRRTNRTCSTRNIPVFDDQNIVLQDG---------------------------KVT 917
               + +   +  ST     + D + V  DG                            VT
Sbjct: 2056 LLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVT 2115

Query: 918  ---------AVKSTESKKCELNANAYS--------IHTVGLYLILKFQ---------NGI 951
                     AV  T S   ++  ++ +        +   G+++ L FQ         +G 
Sbjct: 2116 VANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGA 2175

Query: 952  IVIWDKNTRLSVILDPN----------WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             V+    + LS+  D +          + G +CGLCGN N D  DD        A G   
Sbjct: 2176 DVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLK------AVGGKP 2229

Query: 1002 FGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYH 1057
             G     +Q C + V++    PC             C ++   D     CH  V P+ Y 
Sbjct: 2230 AGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 2289

Query: 1058 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECR 1116
              C+ +  AC ++G   G C AVA Y  AC A G  +  WR+P+ CP  C  ++      
Sbjct: 2290 QGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS------ 2341

Query: 1117 WHYEPCGTVTAKTC 1130
             HYE CG     +C
Sbjct: 2342 -HYELCGDSCPGSC 2354



 Score =  130 bits (328), Expect = 1e-29
 Identities = 141/614 (22%), Positives = 228/614 (37%), Gaps = 112/614 (18%)

Query: 601  EDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 660
            + +I +   +S  L V  +    LQ+      ++ V++P +      GLCG+ +    +D
Sbjct: 4171 DGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNND 4227

Query: 661  FMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSS 712
             +     L  +   +  SW        C      SC +  +++  +      CG L   +
Sbjct: 4228 QVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGT 4287

Query: 713  G-PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL- 770
            G P  +CH  V P+ + + C    C      D LC  L +YV AC      I  WR  + 
Sbjct: 4288 GGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVG 4347

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LK 829
            CE +CP    ++     C +SC S +        E   V+GC C DA +  +   CV L 
Sbjct: 4348 CEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLN 4406

Query: 830  SQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
            + C C+ N    + G     D       +C    G L+C      T  +C  G     C 
Sbjct: 4407 NGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC------TPASCGLGEV---CG 4457

Query: 885  DPKAQRRTNRTCSTRNIPVFDDQNIVLQDG---------------------------KVT 917
               + + + +  ST     + D + V  DG                            VT
Sbjct: 4458 LLPSGQHSCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVT 4517

Query: 918  ---------AVKSTESKKCELNANAYS--------IHTVGLYLILKFQ------------ 948
                     AV  T S   ++  ++ +        +   G+++ L FQ            
Sbjct: 4518 VANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGA 4577

Query: 949  -------NGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
                   +G+ + +D ++ + + +   +   +CGLCGN N D  DD        A G   
Sbjct: 4578 DVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLK------AVGGKP 4631

Query: 1002 FGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYH 1057
             G     +Q C + V++    PC             C ++   D     CH  V P+ Y 
Sbjct: 4632 AGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 4691

Query: 1058 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECR 1116
              C+ +  AC ++G   G C AVA Y  AC A G  +  WR+P+ CP+ C  ++      
Sbjct: 4692 QGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS------ 4743

Query: 1117 WHYEPCGTVTAKTC 1130
             HYE CG     +C
Sbjct: 4744 -HYELCGDSCPVSC 4756



 Score =  130 bits (328), Expect = 1e-29
 Identities = 145/614 (23%), Positives = 226/614 (36%), Gaps = 112/614 (18%)

Query: 601  EDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 660
            + +I +   +S  L V  +    LQ+      ++ V++P +      GLCG+ +    +D
Sbjct: 2970 DGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNND 3026

Query: 661  FMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSS 712
             +     L  +   +  SW        C      SC +  +++  +      CG L   +
Sbjct: 3027 QVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT 3086

Query: 713  G-PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL- 770
            G P  +CH  V P+ + + C    C      D LC  L +YV AC      I  WR  + 
Sbjct: 3087 GGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRAQVG 3146

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LK 829
            CE +CP    ++     C +SC S +        E   V+GC C DA +  +   CV L 
Sbjct: 3147 CEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLN 3205

Query: 830  SQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
            + C C+ N    + G     D       +C    G L+C      T  +C  G     C 
Sbjct: 3206 NGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC------TPASCGLGEV---CG 3256

Query: 885  DPKAQRRTNRTCSTRNIPVFDDQNIVLQDG---------------------------KVT 917
               + +   +  ST     + D + V  DG                            VT
Sbjct: 3257 LLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVT 3316

Query: 918  ---------AVKSTESKKCELNANAYS--------IHTVGLYLILKFQ---------NGI 951
                     AV  T S   ++  ++ +        +   G+++ L FQ         +G 
Sbjct: 3317 VANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGA 3376

Query: 952  IVIWDKNTRLSVILDPN----------WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             V+    + LS+  D +          + G +CGLCGN N D  DD        A G   
Sbjct: 3377 DVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLK------AVGGKP 3430

Query: 1002 FGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYH 1057
             G     +Q C + V++    PC             C ++   D     CH  V P+ Y 
Sbjct: 3431 AGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 3490

Query: 1058 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECR 1116
              C+ +  AC ++G   G C AVA Y  AC A G  +  WR+P+ CP  C  ++      
Sbjct: 3491 QGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS------ 3542

Query: 1117 WHYEPCGTVTAKTC 1130
             HYE CG     +C
Sbjct: 3543 -HYELCGDSCPGSC 3555



 Score =  121 bits (303), Expect = 9e-27
 Identities = 78/270 (28%), Positives = 123/270 (45%), Gaps = 28/270 (10%)

Query: 616  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            +ET F +++   +V  ++  V++P N +    GLCG+YN   +DDF          +  F
Sbjct: 1358 IETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 1415

Query: 676  ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 718
             NSWE +           CP G+   CI        +EK+   E  CG+L   +GPL+SC
Sbjct: 1416 GNSWEEVVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474

Query: 719  HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 777
            H +V+P+   ++C    C    +   LC+ +  YV AC     ++  WRT   C   CP 
Sbjct: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534

Query: 778  GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 837
               ++     C+  C +LS   +    +D   +GC C      N +  CV   QC CY N
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 1590

Query: 838  DEVMQPGKLIHIDD--NKCVCRDGI-LLCQ 864
                +P + + ID+   +C C  G  ++CQ
Sbjct: 1591 GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620



 Score =  120 bits (300), Expect = 2e-26
 Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 28/270 (10%)

Query: 616  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            +ET F +++   +V  ++  V++P N +    GLCG+YN   +DDF          +  F
Sbjct: 2559 IETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 2616

Query: 676  ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 718
             NSWE +          +CP G+   CI        +EK+   E  CG+L   +GPL+SC
Sbjct: 2617 GNSWEEVVPDSPCLPPPTCPPGS-EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSC 2675

Query: 719  HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 777
            H +V+P+   ++C    C    +   LC+ +  YV AC     ++  WR    C   CP 
Sbjct: 2676 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQ 2735

Query: 778  GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 837
               ++     C+  C +LS         D   +GC C      N +  CV   QC CY N
Sbjct: 2736 NSHYELCADTCSLGCSALS---APLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 2791

Query: 838  DEVMQPGKLIHIDD--NKCVCRDG-ILLCQ 864
                +P + + ID+   +C C  G +++CQ
Sbjct: 2792 GAYYEPEQTVLIDNCRQQCTCHAGKVVVCQ 2821



 Score =  119 bits (298), Expect = 4e-26
 Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 28/270 (10%)

Query: 616  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            +ET F +++   +V  ++  V++P N +    GLCG+YN   +DDF          +  F
Sbjct: 3760 IETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 3817

Query: 676  ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 718
             NSWE +          +CP G+   CI        +EK+   E  CG+L   +GPL+SC
Sbjct: 3818 GNSWEEVVPDSPCLPPPTCPPGS-EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSC 3876

Query: 719  HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 777
            H +V+P+   ++C    C    +   LC+ +  YV AC     ++  WR    C   CP 
Sbjct: 3877 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQ 3936

Query: 778  GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 837
               ++     C+  C +LS         D   +GC C      N +  CV   QC CY N
Sbjct: 3937 NSHYELCADTCSLGCSALS---APLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 3992

Query: 838  DEVMQPGKLIHIDD--NKCVCRDG-ILLCQ 864
                +P + + ID+   +C C  G +++CQ
Sbjct: 3993 GVYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 4022



 Score =  105 bits (262), Expect = 5e-22
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 16/209 (7%)

Query: 929  LNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 988
            L+     ++  G   +++   G++V +D + +L++ L   +  +VCGLCGN NGD  DDF
Sbjct: 563  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622

Query: 989  TTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--DS 1042
             T   ++A  A+EF +SWK       C D      P C           R C +L   D 
Sbjct: 623  LTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDG 682

Query: 1043 TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNL 1101
             F  CH+ +DP  + + C+ + C   + G+ L  C  ++ YA+AC  +G+ V  WR P  
Sbjct: 683  PFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740

Query: 1102 CPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
            CP+ C     P   R  YE CG     +C
Sbjct: 741  CPLSC-----PANSR--YELCGPACPTSC 762



 Score = 99.0 bits (245), Expect = 5e-20
 Identities = 95/422 (22%), Positives = 159/422 (37%), Gaps = 75/422 (17%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-----N 688
            L +S+P        GLCG++N    DDF+        + + F  +W +    KG      
Sbjct: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCG 5029

Query: 689  PSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDC 744
            P  C     E+ A       CG L +  GP A+C  +++P  Y  +C    C  +  +  
Sbjct: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 5089

Query: 745  LCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCD 803
            LC  L  Y  AC      +  WRT   C   CP+   +    + C  SC +LS     C 
Sbjct: 5090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLT-GCT 5148

Query: 804  VEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQ--------------------- 842
                  +GC C D  +  ++G C+    C C  N   +                      
Sbjct: 5149 TRCF--EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSG 5205

Query: 843  ---------PGKLIHI--DDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRR 891
                     PG++  +  +   C    G+ +  +  +LT  + + GA     + P     
Sbjct: 5206 LTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGAT----TSPGVYEL 5261

Query: 892  TNRTCSTRN-IPVF----------------DDQNIVLQDGKVTAVKS----TESKKCELN 930
            ++R    +N IP +                   +I  QDG VT   +        + +L 
Sbjct: 5262 SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP 5321

Query: 931  ANAYSIHTVGLY----LILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKD 986
            A   +  +V       L+++ + G+ V    N +++VI+  +  GK+CG CGN +GD  +
Sbjct: 5322 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 5381

Query: 987  DF 988
            D+
Sbjct: 5382 DW 5383



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 38/136 (27%), Positives = 50/136 (36%), Gaps = 13/136 (9%)

Query: 472  GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 528
            G CP       E  E G   C  +    G  F  C       + +K   +D      D+ 
Sbjct: 1859 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917

Query: 529  STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 588
              C   +     C + G    E WR+   V C    CPE   Y+ CGP  PA+C + AP 
Sbjct: 1918 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 1973

Query: 589  Q-----DSECVSGCTC 599
                  +  CV GC C
Sbjct: 1974 TTPAVCEGPCVEGCQC 1989



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 38/136 (27%), Positives = 49/136 (36%), Gaps = 13/136 (9%)

Query: 472  GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 528
            G CP       E  E G   C  +    G  F  C       + +K   +D      D  
Sbjct: 4261 GSCPTCPEDRLEQYE-GPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHD 4319

Query: 529  STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 588
              C   +     C + G    E WR+   V C    CPE   Y+ CGP  PA+C + AP 
Sbjct: 4320 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 4375

Query: 589  Q-----DSECVSGCTC 599
                  +  CV GC C
Sbjct: 4376 TTPAVCEGPCVEGCQC 4391



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 38/136 (27%), Positives = 49/136 (36%), Gaps = 13/136 (9%)

Query: 472  GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 528
            G CP       E  E G   C  +    G  F  C       + +K   +D      D  
Sbjct: 3060 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHD 3118

Query: 529  STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 588
              C   +     C + G    E WR+   V C    CPE   Y+ CGP  PA+C + AP 
Sbjct: 3119 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 3174

Query: 589  Q-----DSECVSGCTC 599
                  +  CV GC C
Sbjct: 3175 TTPAVCEGPCVEGCQC 3190



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 27/139 (19%)

Query: 484 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 524
           +CEDG Q+    C      ++E    CG +  L   + +             C+ + C  
Sbjct: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707

Query: 525 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
             ++ S C   S  ++ C   G    + WRS ++       CP    Y+ CGP+ P +C+
Sbjct: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763

Query: 584 NVAPFQDSE---CVSGCTC 599
             A   +     CV GC C
Sbjct: 764 GAAAPSNCSGRPCVEGCVC 782



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 517  CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + C    ++   CD  +  +  C + G  T   WRS+   +C    CP    Y+ C 
Sbjct: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146

Query: 576  PSNPATCSN--VAPFQDSECVSGCTCPE 601
               P +C +  V     SEC  GC C E
Sbjct: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDE 1174



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 517  CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + CQ +      C   +     C + G    E  R D    C  Q CP    Y+ CG
Sbjct: 4694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 4749

Query: 576  PSNPATCSNVAPFQ--DSECVSGCTC 599
             S P +C +++  +  +S C  GC C
Sbjct: 4750 DSCPVSCPSLSAPEGCESACREGCVC 4775



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 517  CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + CQ +      C   +     C + G    E  R D    C  Q CP    Y+ CG
Sbjct: 3493 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 3548

Query: 576  PSNPATCSNVAPFQ--DSECVSGCTC 599
             S P +C +++  +  +S C  GC C
Sbjct: 3549 DSCPGSCPSLSAPEGCESACREGCVC 3574



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 517  CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + CQ +      C   +     C + G    E  R D    C  Q CP    Y+ CG
Sbjct: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 2347

Query: 576  PSNPATCSNVAPFQ--DSECVSGCTC 599
             S P +C +++  +  +S C  GC C
Sbjct: 2348 DSCPGSCPSLSAPEGCESACREGCVC 2373



>gi|5080756|gb|AAD39266.1|   Human Fc gamma BP [AA 1-2843] [Homo sapiens]
          Length = 2843

 Score =  162 bits (411), Expect = 3e-39
 Identities = 152/573 (26%), Positives = 227/573 (39%), Gaps = 84/573 (14%)

Query: 633  QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKG- 687
            QL +S+P        GLCG+YN    DDF++    L   +  FA+SW++      C  G 
Sbjct: 594  QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGC 653

Query: 688  --NPSSCISIEKEKF-AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDC 744
              N  +C   + + +  +R CG+L    GP A CH  ++P+P+ E+C    C     +  
Sbjct: 654  QNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLS 713

Query: 745  LCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKA----CNSSCRSLSERD 799
            LC  L  Y +AC E    +  WR+   C  SCP+   ++    A    CN +    +   
Sbjct: 714  LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG 773

Query: 800  RSCDVED--------------VPVDGCTCPDAMYQNNEGNCV-----LKSQCDCY-INDE 839
            R C VE               VP   C C     Q   G  V      + +C C     +
Sbjct: 774  RPC-VEGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ 832

Query: 840  VMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVD----------------- 882
            V    K       +C  ++G+L C      T Q  SG   YV                  
Sbjct: 833  VTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQG-SGDPHYVSFDGRRFDFMGTCTYLLV 891

Query: 883  --CSDPKA----------QRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESK 925
              C    A          + R ++T S       + + + +       G+V      +  
Sbjct: 892  GSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYL 951

Query: 926  KCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLK 985
              +       +   G   +++   G+ V +D N R++  +  ++   +CGLCGN NGD  
Sbjct: 952  PFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPA 1011

Query: 986  DDFTTRYSSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD- 1041
            DD   R    A+ AL FGNSW  +T   C  T     P  DS    +  +  +C IL D 
Sbjct: 1012 DDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADP 1071

Query: 1042 -STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKP 1099
               FR+CH+K+DP      C+ + C   + G+    C A+A YA AC A G  V  WR  
Sbjct: 1072 KGPFRECHSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSE 1129

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
             LCP+ C  ++       HYE C      +C D
Sbjct: 1130 ELCPLSCPPHS-------HYEACSYGCPLSCGD 1155



 Score =  142 bits (358), Expect = 4e-33
 Identities = 143/571 (25%), Positives = 204/571 (35%), Gaps = 117/571 (20%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGNPSSCISIEKEKF 700
            GLCG+YN    DD         K        W++     C     K  PS C   ++E F
Sbjct: 2209 GLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESF 2260

Query: 701  AERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 759
                 CG++  + GPLA CH +V P  Y + C    C  +     LC  +  YV AC   
Sbjct: 2261 GGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320

Query: 760  ETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 818
               +  W R   C   CP+   ++    +C  SC SLS  +     E    +GC C DA 
Sbjct: 2321 GAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCESACREGCVC-DAG 2376

Query: 819  YQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRD-GILLCQ---------- 864
            +  +   CV   QC C  +D     G+  +     D+ C CR+ G + C+          
Sbjct: 2377 FVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETC 2436

Query: 865  ---------IPIDLTLQNCSGGAEYVDCSDPKAQRRTN------RTCSTR----NIPVFD 905
                     + +  T    SG   Y      +            +TC TR       V  
Sbjct: 2437 RPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVL- 2495

Query: 906  DQNIVLQDGKVTAVK-----------STESKKCELNANAYSIHTV-------------GL 941
             +N+   +G+V+  +             E ++ ++  N   +                G 
Sbjct: 2496 QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGS 2555

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             ++++   G+ V +D    + V +  N+   +CGLCGN NGD KDDF     S A  A E
Sbjct: 2556 DVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE 2615

Query: 1002 FGNSWKTSQECSDTVAQTFPCDSNPYC-------------------KAWAVRKCEILRDS 1042
            FGNSW       + V    PC   P C                   K      C +L   
Sbjct: 2616 FGNSW-------EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSP 2668

Query: 1043 T--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKP 1099
            T     CH  VDP      CI + C     G     C+ +  Y  AC A G  V  WR  
Sbjct: 2669 TGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGQVEPWRNE 2726

Query: 1100 NLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
              CP+ C   +       HYE C    +  C
Sbjct: 2727 TFCPMECPQNS-------HYELCADTCSLGC 2750



 Score =  139 bits (349), Expect = 4e-32
 Identities = 141/573 (24%), Positives = 213/573 (37%), Gaps = 97/573 (16%)

Query: 640  PNQFTDTV-GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNPSSCISI 695
            P+ + + + GLCG++N    DD           + AF NSW+  +   C    P  C  +
Sbjct: 992  PSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL 1051

Query: 696  E----KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGN 751
            +    ++  ++  CGIL D  GP   CH  ++P+    +C    C        LC  L  
Sbjct: 1052 DSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALAT 1111

Query: 752  YVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVD 810
            Y  AC      +  WR+  LC  SCP    ++     C  SC  L      C  E    +
Sbjct: 1112 YAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHE 1168

Query: 811  GCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL----- 862
            GC C +    + E +C+  + C C        PG+  +     D+ C C++G L+     
Sbjct: 1169 GCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227

Query: 863  -------CQ--------IPIDLTLQNCSGGAEYVDCSDPKAQRRTN------RTCSTR-- 899
                   CQ        + +  +    SG   Y      +            +TC TR  
Sbjct: 1228 SCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPG 1287

Query: 900  --NIPVFDDQNIVLQDGKVTAVK-----------STESKKCELNANAYSIHTV------- 939
                 V   +N+   +G+V+  +             E ++ ++  N   +          
Sbjct: 1288 LHRFAVL-QENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQ 1346

Query: 940  ------GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYS 993
                  G  ++++   G+ V +D    + V +  N+  ++CGLCGN NGD KDDF     
Sbjct: 1347 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNG 1406

Query: 994  SVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK------CEILR 1040
            S A  A EFGNSW+     S  +  T PC     D  P   C     +K      C +L 
Sbjct: 1407 SQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465

Query: 1041 DST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WR 1097
              T     CH  VDP      CI + C     G     C+ +  Y  AC A G  V  WR
Sbjct: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWR 1523

Query: 1098 KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
                CP+ C   +       HYE C    +  C
Sbjct: 1524 TETFCPMECPPNS-------HYELCADTCSLGC 1549



 Score =  131 bits (330), Expect = 7e-30
 Identities = 145/614 (23%), Positives = 227/614 (36%), Gaps = 112/614 (18%)

Query: 601  EDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 660
            + +I +   +S  L V  +    LQ+      ++ V++P +      GLCG+ +    +D
Sbjct: 1769 DGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNND 1825

Query: 661  FMSSQNILEKTSQAFANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSS 712
             +     L  +   +  SW        C      SC +  +++  +      CG L   +
Sbjct: 1826 QVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT 1885

Query: 713  G-PLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL- 770
            G P  +CH  V P+ + + C    C     +D LC  L +YV AC      I  WR  + 
Sbjct: 1886 GGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG 1945

Query: 771  CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LK 829
            CE +CP    ++     C +SC S +        E   V+GC C DA +  +   CV L 
Sbjct: 1946 CEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLN 2004

Query: 830  SQCDCYINDEVMQPGKLIHIDDN-----KCVCRDGILLCQIPIDLTLQNCSGGAEYVDCS 884
            + C C+ N    + G     D       +C    G L+C      T  +C  G     C 
Sbjct: 2005 NGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC------TPASCGLGEV---CG 2055

Query: 885  DPKAQRRTNRTCSTRNIPVFDDQNIVLQDG---------------------------KVT 917
               + +   +  ST     + D + V  DG                            VT
Sbjct: 2056 LLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVT 2115

Query: 918  ---------AVKSTESKKCELNANAYS--------IHTVGLYLILKFQ---------NGI 951
                     AV  T S   ++  ++ +        +   G+++ L FQ         +G 
Sbjct: 2116 VANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGA 2175

Query: 952  IVIWDKNTRLSVILDPN----------WNGKVCGLCGNNNGDLKDDFTTRYSSVASGALE 1001
             V+    + LS+  D +          + G +CGLCGN N D  DD        A G   
Sbjct: 2176 DVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLK------AVGGKP 2229

Query: 1002 FGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYH 1057
             G     +Q C + V++    PC             C ++   D     CH  V P+ Y 
Sbjct: 2230 AGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYF 2289

Query: 1058 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECR 1116
              C+ +  AC ++G   G C AVA Y  AC A G  +  WR+P+ CP  C  ++      
Sbjct: 2290 QGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS------ 2341

Query: 1117 WHYEPCGTVTAKTC 1130
             HYE CG     +C
Sbjct: 2342 -HYELCGDSCPGSC 2354



 Score =  121 bits (303), Expect = 9e-27
 Identities = 78/270 (28%), Positives = 123/270 (45%), Gaps = 28/270 (10%)

Query: 616  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            +ET F +++   +V  ++  V++P N +    GLCG+YN   +DDF          +  F
Sbjct: 1358 IETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 1415

Query: 676  ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 718
             NSWE +           CP G+   CI        +EK+   E  CG+L   +GPL+SC
Sbjct: 1416 GNSWEEVVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474

Query: 719  HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 777
            H +V+P+   ++C    C    +   LC+ +  YV AC     ++  WRT   C   CP 
Sbjct: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534

Query: 778  GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 837
               ++     C+  C +LS   +    +D   +GC C      N +  CV   QC CY N
Sbjct: 1535 NSHYELCADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 1590

Query: 838  DEVMQPGKLIHIDD--NKCVCRDGI-LLCQ 864
                +P + + ID+   +C C  G  ++CQ
Sbjct: 1591 GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620



 Score =  118 bits (296), Expect = 6e-26
 Identities = 77/270 (28%), Positives = 121/270 (44%), Gaps = 28/270 (10%)

Query: 616  VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            +ET F +++   +V  ++  V++P N +    GLCG+YN   +DDF          +  F
Sbjct: 2559 IETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEF 2616

Query: 676  ANSWEMM----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASC 718
             NSWE +          +CP G+   CI        +EK+   E  CG+L   +GPL+SC
Sbjct: 2617 GNSWEEVVPDSPCLPPPTCPPGS-EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSC 2675

Query: 719  HPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPS 777
            H +V+P+   ++C    C    +   LC+ +  YV AC      +  WR    C   CP 
Sbjct: 2676 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQ 2735

Query: 778  GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIN 837
               ++     C+  C +LS         D   +GC C      N +  CV   QC CY N
Sbjct: 2736 NSHYELCADTCSLGCSALS---APLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHN 2791

Query: 838  DEVMQPGKLIHIDD--NKCVCRDG-ILLCQ 864
                +P + + ID+   +C C  G +++CQ
Sbjct: 2792 GAYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 2821



 Score =  105 bits (262), Expect = 5e-22
 Identities = 65/209 (31%), Positives = 100/209 (47%), Gaps = 16/209 (7%)

Query: 929  LNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 988
            L+     ++  G   +++   G++V +D + +L++ L   +  +VCGLCGN NGD  DDF
Sbjct: 563  LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622

Query: 989  TTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--DS 1042
             T   ++A  A+EF +SWK       C D      P C           R C +L   D 
Sbjct: 623  LTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDG 682

Query: 1043 TFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNL 1101
             F  CH+ +DP  + + C+ + C   + G+ L  C  ++ YA+AC  +G+ V  WR P  
Sbjct: 683  PFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740

Query: 1102 CPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
            CP+ C     P   R  YE CG     +C
Sbjct: 741  CPLSC-----PANSR--YELCGPACPTSC 762



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 37/136 (27%), Positives = 49/136 (36%), Gaps = 13/136 (9%)

Query: 472  GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 528
            G CP       E  E G   C  +    G  F  C       + +K   +D      D+ 
Sbjct: 1859 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917

Query: 529  STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 588
              C   +     C + G    E WR+   V C    CPE   Y+ CG   PA+C + AP 
Sbjct: 1918 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGSPCPASCPSPAPL 1973

Query: 589  Q-----DSECVSGCTC 599
                  +  CV GC C
Sbjct: 1974 TTPAVCEGPCVEGCQC 1989



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 34/139 (24%), Positives = 55/139 (39%), Gaps = 27/139 (19%)

Query: 484 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 524
           +CEDG Q+    C      ++E    CG +  L   + +             C+ + C  
Sbjct: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707

Query: 525 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
             ++ S C   S  ++ C   G    + WRS ++       CP    Y+ CGP+ P +C+
Sbjct: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763

Query: 584 NVAPFQDSE---CVSGCTC 599
             A   +     CV GC C
Sbjct: 764 GAAAPSNCSGRPCVEGCVC 782



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 7/88 (7%)

Query: 517  CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + C    ++   CD  +  +  C + G  T   WRS+   +C    CP    Y+ C 
Sbjct: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146

Query: 576  PSNPATCSN--VAPFQDSECVSGCTCPE 601
               P +C +  V     SEC  GC C E
Sbjct: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDE 1174



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 517  CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
            C+ + CQ +      C   +     C + G    E  R D    C  Q CP    Y+ CG
Sbjct: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 2347

Query: 576  PSNPATCSNVAPFQ--DSECVSGCTC 599
             S P +C +++  +  +S C  GC C
Sbjct: 2348 DSCPGSCPSLSAPEGCESACREGCVC 2373



>gi|15722000|gb|AAL04415.1|   zonadhesin splice variant 2 [Homo sapiens]
          Length = 2689

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 31/205 (15%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
                C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 2633

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGC 812
            C +SC +L++     D E   V+GC
Sbjct: 2634 CPASCANLADPG---DCEGPCVEGC 2655



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 2611 WRDRTLCAMEC 2621



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSD 555
            F  C +  A    ++  C+ + C  +D        C   S  + LC   G      WR  
Sbjct: 2557 FAACHQTVA-PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDR 2614

Query: 556  SDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGC 597
            +  +C  + CP   IY+ C    PA+C+N+A   D E  CV GC
Sbjct: 2615 T--LCAME-CPAGTIYQSCMTPCPASCANLADPGDCEGPCVEGC 2655



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|15721999|gb|AAL04414.1|   zonadhesin splice variant 4 [Homo sapiens]
          Length = 2624

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 27/159 (16%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR 767
                C+ ++    ++  C +L  Y   C E    + GWR
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWR 2612



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 46/187 (24%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLC 1102
            WR   LC
Sbjct: 2611 WRDRTLC 2617



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|15721998|gb|AAL04413.1|   zonadhesin splice variant 6 [Homo sapiens]
          Length = 2721

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 28/168 (16%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSC 775
                C+ ++    ++  C +L  Y   C E    + GWR   LCE  C
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 30/203 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC--DYYNAPGECR 1116
            WR   LC   C  +     G+CR
Sbjct: 2611 WRDRTLCESPCLQNPCQNDGQCR 2633



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|15721997|gb|AAL04412.1|   zonadhesin splice variant 5 [Homo sapiens]
          Length = 2601

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 27/147 (18%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKA 755
                C+ ++    ++  C +L  +  A
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGWAAA 2600



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 26/149 (17%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             D    F  CH  V P  + + C+ + C+
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|15721996|gb|AAL04411.1|   zonadhesin splice variant 3 [Homo sapiens]
 gi|27924006|sp|Q9Y493|ZAN_HUMAN   Zonadhesin precursor
          Length = 2812

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 27/144 (18%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNY 752
                C+ ++    ++  C +L  +
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGH 2597



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 26/149 (17%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             D    F  CH  V P  + + C+ + C+
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|15721995|gb|AAL04410.1|   zonadhesin splice variant 1 [Homo sapiens]
          Length = 2724

 Score =  148 bits (373), Expect = 7e-35
 Identities = 142/580 (24%), Positives = 223/580 (38%), Gaps = 91/580 (15%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQN------NEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N    Q    P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVK 920
            +   C+                    K ++    T + R   V+ D    + D +VT  K
Sbjct: 1949 IPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEVYID----IYDAQVTLQK 2004

Query: 921  S----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
                   SK+  L A +     S+ +  +Y I+  + G+ V +D N  L + +   + GK
Sbjct: 2005 GHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD--------- 1023
            VCG+CGN N + +D+       VA+   EF NSWK      D   Q+ P D         
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQ 2122

Query: 1024 SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1076
             NP   C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   
Sbjct: 2123 ENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQAL 2180

Query: 1077 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2181 CQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 31/205 (15%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
                C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 2633

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGC 812
            C +SC +L++     D E   V+GC
Sbjct: 2634 CPASCANLADPG---DCEGPCVEGC 2655



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 2022 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2081

Query: 663  SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
               + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 2082 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 2141

Query: 706  GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
               L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 2142 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 2200

Query: 766  WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
            WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 2201 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 2259

Query: 825  NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
             CV +SQC C        P     +      KCVC  G + C
Sbjct: 2260 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 2301



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 2611 WRDRTLCAMEC 2621



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSD 555
            F  C +  A    ++  C+ + C  +D        C   S  + LC   G      WR  
Sbjct: 2557 FAACHQTVA-PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDR 2614

Query: 556  SDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGC 597
            +  +C  + CP   IY+ C    PA+C+N+A   D E  CV GC
Sbjct: 2615 T--LCAME-CPAGTIYQSCMTPCPASCANLADPGDCEGPCVEGC 2655



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|4885627|ref|NP_005413.1|   tectorin alpha precursor [Homo sapiens]
 gi|3309151|gb|AAC26019.1|   alpha-tectorin [Homo sapiens]
 gi|48428570|sp|O75443|TECA_HUMAN   Alpha-tectorin precursor
          Length = 2155

 Score =  147 bits (372), Expect = 9e-35
 Identities = 132/577 (22%), Positives = 220/577 (38%), Gaps = 89/577 (15%)

Query: 601  EDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD 660
            + KI IF+    ++ VET F +K+       +   +++P +    T GLCG YN   +DD
Sbjct: 1195 QGKINIFSFGF-HVVVETDFGLKVVYDWKTFLS--ITVPRSMQNSTYGLCGRYNGNPDDD 1251

Query: 661  FMSSQNILEKTSQAFANSWE------MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGP 714
                  +L  +   F  SW        + C    PS C  +E     ++ C ++ + +  
Sbjct: 1252 LEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPS-CAKVEGFSKVQQLCSLIPNQNAA 1310

Query: 715  LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 773
             + CH  VNP  +++ C   +C    +    C+ L NY   C  +   + GWR    C  
Sbjct: 1311 FSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTV 1370

Query: 774  SCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCD 833
            +CP    ++  V  C   C ++  +    D     V+GC C DA Y  N  +C+L   C 
Sbjct: 1371 TCPPNSHYESCVSVCQPRCAAIRLKS---DCSHYCVEGCHC-DAGYVLNGKSCILPHSCG 1426

Query: 834  CYINDEVMQPGKL-----------------IHID------DNKCVCRDGILLCQIPIDLT 870
            CY + +  +P +L                 I  D      D +C  R+G+  C       
Sbjct: 1427 CYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGC---FSTK 1483

Query: 871  LQNCSGGAEYVDCSDPKAQRRTNRTC-------------------------STRNI---- 901
               C      V  +   A  R    C                         S  N+    
Sbjct: 1484 TSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIIS 1543

Query: 902  PVF---DDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKN 958
            PV+   +++ I++ D     V  T+     +   A  I++   +L++     I + ++  
Sbjct: 1544 PVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGF 1603

Query: 959  TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT--------SQ 1010
              + + +      KVCGLCGN NGDL DD+ T        ++    SWKT        + 
Sbjct: 1604 NVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAP 1663

Query: 1011 ECSDTVAQTFP--CDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             C++     +   CD+    K      C  L D    F+ C+  +DP  +++ C  + C 
Sbjct: 1664 SCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC- 1722

Query: 1067 CDMEGKYLGFCTAVAMYAEACSAVGV-CVSWRKPNLC 1102
                 K    C ++A Y EAC + G+    W +   C
Sbjct: 1723 --YNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757



 Score =  144 bits (362), Expect = 1e-33
 Identities = 146/609 (23%), Positives = 232/609 (38%), Gaps = 99/609 (16%)

Query: 600  PEDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAED 659
            P  K++I+   +S   VE+   V +Q   + +  LY+ +    F  T GLCG YN  A D
Sbjct: 802  PSGKLEIYRNKNS-TTVESKGVVTVQYSDIGL--LYIRLSTTYFNCTGGLCGFYNANASD 858

Query: 660  DFMSSQNILEKTSQAFANSW----EMMSCPKGNPSSCISIEKE--KF--AERHCGILLD- 710
            +F             F  SW    E+ +   G+     + + E  KF  +   CGI+ D 
Sbjct: 859  EFCLPNGKCTDNLAVFLESWTTFEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDP 918

Query: 711  SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-G 769
            S+     CH +VN   Y+  C    C    ++  LC  +  Y  AC   +  +  WRT  
Sbjct: 919  SNSSFLECHGVVNATAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYD 978

Query: 770  LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 829
             C   CP    F+  +  C  +C +L+      D      +GC C D  Y      CV +
Sbjct: 979  FCPLECPENSHFEECI-TCTETCETLTLGPICVDSCS---EGCQC-DEGYALLGSQCVTR 1033

Query: 830  SQCDCYINDEVMQPGKLIHI-------------------------DDNKCVCRDGILLCQ 864
            S+C C      +   +   +                         DD  C+   G+  CQ
Sbjct: 1034 SECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQ 1093

Query: 865  IPIDLT------------------------LQNCSGGAEYVDCSDPK---AQRRTNRTCS 897
               D +                        L  C+ G+     S PK     +  +R  S
Sbjct: 1094 ARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPS 1153

Query: 898  TR------NIPVFDDQNIVLQDGKVTAVKSTES--KKCELNANAYSIHTVGLYLILKFQN 949
                    ++ VF    ++ +  K T + ++E      +L     +I + G +++++   
Sbjct: 1154 LALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDF 1213

Query: 950  GIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS 1009
            G+ V++D  T LS+ +  +      GLCG  NG+  DD       +AS   EFG SW   
Sbjct: 1214 GLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVK- 1272

Query: 1010 QECSDTVAQTFPCDSNPYC-KAWAVRKCEIL------RDSTFRDCHNKVDPSAYHDVCIE 1062
                DT  Q    D  P C K     K + L      +++ F  CH+KV+P+ ++  C+ 
Sbjct: 1273 ---RDTFCQVGCGDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLF 1329

Query: 1063 EACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEP 1121
            ++C     G     C+ +  YA  C   G+ V+ WR    C V C   +       HYE 
Sbjct: 1330 DSCIDG--GAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNS-------HYES 1380

Query: 1122 CGTVTAKTC 1130
            C +V    C
Sbjct: 1381 CVSVCQPRC 1389



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 58/238 (24%), Positives = 91/238 (38%), Gaps = 18/238 (7%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SCPKGNPSS 691
           +S+P +    T GLCG+YN    DDF+        +      SW +      C  G   +
Sbjct: 447 ISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDN 506

Query: 692 CI----SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 747
           C     + E   F   +CG L  + GPL  C  +V+P  +   C    C+  ++   LC 
Sbjct: 507 CTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQ 566

Query: 748 ILGNYVKACAEKETYIVGWRTG---LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDV 804
            +  Y   C      I  WRT    +    CPS   +     +C  +C  L+   R+C  
Sbjct: 567 AIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLT-ASRNCAT 625

Query: 805 EDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDN---KCVCRDG 859
                +GC C    +  +   CV   +C C  +      G+      N   +C+C +G
Sbjct: 626 P--CTEGCECNQG-FVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCLCEEG 680



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 61/231 (26%), Positives = 91/231 (39%), Gaps = 24/231 (10%)

Query: 914  GKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKV 973
            G+V       S    L+     I+  G+   ++   G++V +D     S+ +  ++    
Sbjct: 398  GRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINST 457

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNS-------WKTSQECSDTVAQTFPCDSNP 1026
            CGLCGN N +  DDF       A   L+ G S       WK    C D   Q   CD+  
Sbjct: 458  CGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQ---CDAAT 514

Query: 1027 YCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYA 1084
                +    C  L   D    +C   VDP+A+   C+ + C+    G  L  C A+  YA
Sbjct: 515  EALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLL--CQAIQAYA 572

Query: 1085 EACSAVGVCV-SWRKPNLC--PVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1132
              C A+G+ +  WR    C   V C  ++       HY  C +    TC D
Sbjct: 573  LVCQALGIPIGDWRTQTGCVSTVQCPSFS-------HYSVCTSSCPDTCSD 616



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 60/285 (21%), Positives = 108/285 (37%), Gaps = 49/285 (17%)

Query: 624  LQIQIVPVMQLY--------VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 675
            L I   P +Q+Y        +S+         GLCG++N    DD+++ +     +S   
Sbjct: 1588 LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVL 1647

Query: 676  ANSWEMMSCPKGN-PSSCISIEKEKFA-------------ERHCGILLDSSGPLASCHPI 721
            A SW+     K     SC  ++  ++A             + +C  L D  G    C+ +
Sbjct: 1648 AQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGL 1707

Query: 722  VNPKPYHEECKKYTCTCENSQDC-LCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLV 780
            ++P P++E C  Y   C N +   LC  L  Y +AC         W   + + +C SG+V
Sbjct: 1708 LDPLPFYESC--YLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEW---IEKENC-SGVV 1761

Query: 781  FKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEV 840
                       C      +R+C++ +   + C C +     N  + ++ ++  C      
Sbjct: 1762 --------EDPCVGADCPNRTCELGN-GRELCGCIEPPPYGNNSHDIIDAEVTCKAAQME 1812

Query: 841  MQPGKL-----------IHIDDNKCVCRDGILLCQIPIDLTLQNC 874
            +   K            + I+D +C   +G       I+ T  NC
Sbjct: 1813 VSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNC 1857



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 488 GIQHC---NKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDK-TSTCDTYSELSRLCAS 543
           G  +C   NK  G  +E CG V      +   C+ + C  RD  T  C      + +C +
Sbjct: 520 GSDYCGFLNKTDGPLWE-CGTVVD-PTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQA 577

Query: 544 DGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTC 599
            G      WR+ +  V  T +CP    Y  C  S P TCS++   ++  + C  GC C
Sbjct: 578 LGI-PIGDWRTQTGCV-STVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCEC 633



>gi|27881494|ref|NP_775082.1|   zonadhesin isoform 6 [Homo sapiens]
 gi|12667420|gb|AAK01436.1|   zonadhesin variant 6 [Homo sapiens]
          Length = 2721

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 45/168 (26%), Positives = 69/168 (41%), Gaps = 28/168 (16%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSC 775
                C+ ++    ++  C +L  Y   C E    + GWR   LCE  C
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 30/203 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC--DYYNAPGECR 1116
            WR   LC   C  +     G+CR
Sbjct: 2611 WRDRTLCESPCLQNPCQNDGQCR 2633



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|27881492|ref|NP_775081.1|   zonadhesin isoform 5 [Homo sapiens]
 gi|12667418|gb|AAK01435.1|   zonadhesin variant 5 [Homo sapiens]
          Length = 2601

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 27/147 (18%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKA 755
                C+ ++    ++  C +L  +  A
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGWAAA 2600



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 26/149 (17%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             D    F  CH  V P  + + C+ + C+
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|27881490|ref|NP_775080.1|   zonadhesin isoform 4 [Homo sapiens]
 gi|12667416|gb|AAK01434.1|   zonadhesin variant 4 [Homo sapiens]
          Length = 2624

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 27/159 (16%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR 767
                C+ ++    ++  C +L  Y   C E    + GWR
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWR 2612



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 46/187 (24%), Positives = 73/187 (39%), Gaps = 28/187 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLC 1102
            WR   LC
Sbjct: 2611 WRDRTLC 2617



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|27881488|ref|NP_775079.1|   zonadhesin isoform 2 [Homo sapiens]
 gi|12667412|gb|AAK01432.1|   zonadhesin variant 2 [Homo sapiens]
          Length = 2689

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 31/205 (15%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
                C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 2633

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGC 812
            C +SC +L++     D E   V+GC
Sbjct: 2634 CPASCANLADPG---DCEGPCVEGC 2655



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 2611 WRDRTLCAMEC 2621



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSD 555
            F  C +  A    ++  C+ + C  +D        C   S  + LC   G      WR  
Sbjct: 2557 FAACHQTVA-PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDR 2614

Query: 556  SDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGC 597
            +  +C  + CP   IY+ C    PA+C+N+A   D E  CV GC
Sbjct: 2615 T--LCAME-CPAGTIYQSCMTPCPASCANLADPGDCEGPCVEGC 2655



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|27881486|ref|NP_775078.1|   zonadhesin isoform 1 [Homo sapiens]
 gi|12667410|gb|AAK01431.1|   zonadhesin variant 1 [Homo sapiens]
          Length = 2724

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 31/205 (15%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
                C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 2633

Query: 788  CNSSCRSLSERDRSCDVEDVPVDGC 812
            C +SC +L++     D E   V+GC
Sbjct: 2634 CPASCANLADPG---DCEGPCVEGC 2655



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 2610

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 2611 WRDRTLCAMEC 2621



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSD 555
            F  C +  A    ++  C+ + C  +D        C   S  + LC   G      WR  
Sbjct: 2557 FAACHQTVA-PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDR 2614

Query: 556  SDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGC 597
            +  +C  + CP   IY+ C    PA+C+N+A   D E  CV GC
Sbjct: 2615 T--LCAME-CPAGTIYQSCMTPCPASCANLADPGDCEGPCVEGC 2655



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|16554449|ref|NP_003377.1|   zonadhesin isoform 3 [Homo sapiens]
 gi|12667414|gb|AAK01433.1|   zonadhesin variant 3 [Homo sapiens]
          Length = 2812

 Score =  146 bits (368), Expect = 3e-34
 Identities = 137/575 (23%), Positives = 222/575 (38%), Gaps = 81/575 (14%)

Query: 619  YFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANS 678
            Y +  LQ++      + V++P +      GLCG+YNN + DD +     L   S     +
Sbjct: 1649 YTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAA 1708

Query: 679  WEMMSCPK-------GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
            W++    +       G PSSC          ++C IL++  GP + CH +V P+     C
Sbjct: 1709 WKLPESSEPGCFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASC 1768

Query: 732  KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSS 791
                C  +     LC  L  Y   CA+            C   CP G  +      C  +
Sbjct: 1769 VHGQCGTKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDT 1828

Query: 792  CRSLSE-RD--------RSCDVED---------VPVD--GCTCPDAMYQ------NNEGN 825
            C S++  RD         SC+ +          VP+   GCT P   Y         E  
Sbjct: 1829 CSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENT 1888

Query: 826  CVLKSQCDCYIN----DEVMQPGKLIHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEY 880
            C     C  + N        +P ++    D    CR  G+ +CQ+P +    +  G    
Sbjct: 1889 CTRLCTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHS 1948

Query: 881  VD--CS------------------DPKAQRRTNRTCSTR----NIPVFDDQNIVLQDGKV 916
            +   C+                    K ++    T + R     I ++D Q + LQ G  
Sbjct: 1949 IPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQ-VTLQKGHR 2007

Query: 917  TAVKSTESKKCELN-ANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCG 975
              + S +     ++     S+ +  +Y I+  + G+ V +D N  L + +   + GKVCG
Sbjct: 2008 VLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCG 2067

Query: 976  LCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ---ECSDTVA--QTFPCD--SNP-- 1026
            +CGN N + +D+       VA+   EF NSWK       C   +   Q  P +   NP  
Sbjct: 2068 MCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSG 2127

Query: 1027 YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVA 1081
             C+A  +R    KCE  LR   +  C +++D + +   C      C+  G Y   C A+ 
Sbjct: 2128 NCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQ 2185

Query: 1082 MYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
             +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 2220



 Score =  137 bits (346), Expect = 1e-31
 Identities = 139/605 (22%), Positives = 227/605 (37%), Gaps = 110/605 (18%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1252 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1309

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1310 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1369

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSG 778
              V    + + C    C  +  Q  LCT +      C +    +  WR    C  +CP  
Sbjct: 1370 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPN 1429

Query: 779  LVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDCY-- 835
              +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C   
Sbjct: 1430 SKYSLCAKPCPDTCHS-GFSGMFCS--DRCVEACECNPGFVLSGLE--CIPRSQCGCLHP 1484

Query: 836  ------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ--------- 864
                  + +   +PG  +L   + N               C  +DGI  C          
Sbjct: 1485 AGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTA 1544

Query: 865  ------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQNIVL 911
                  +  D  L +  G   YV            R C +R+   +       +++  +L
Sbjct: 1545 SGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRGGIL 1594

Query: 912  QDGKVTAVKSTES-------KKCELNANAYSIH----------TVGLY--LILKFQN-GI 951
            +   + AV  T         + C++  N + +           T+ L   L+L + N G+
Sbjct: 1595 EVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654

Query: 952  IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1011
             V +D +  + V +  ++ G++CGLCGN N +  DD       +A  +++ G +WK  + 
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714

Query: 1012 ----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1065
                C     +   C  N    AW  + C IL      F  CH  V P +    C+   C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTV 1125
                +G     C ++  YA  C+  G   +WR    CP+ C     PG     Y PC + 
Sbjct: 1774 G--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCPMRC----PPGS---SYSPCSSP 1824

Query: 1126 TAKTC 1130
               TC
Sbjct: 1825 CPDTC 1829



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 95/394 (24%), Positives = 155/394 (39%), Gaps = 73/394 (18%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCD 833
            CP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C+
Sbjct: 1044 CPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSCN 1094

Query: 834  CYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS--------------- 875
            C+ N++  +PG      +    C C  G  + CQI    T   C                
Sbjct: 1095 CFYNNDYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTA 1154

Query: 876  -----GGAEYV----------------------DCSDP--------KAQRRTNRTCSTRN 900
                 G   YV                      + +DP        + Q +   +C ++ 
Sbjct: 1155 TCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKV 1214

Query: 901  IPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 960
                 +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + +
Sbjct: 1215 YVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQ 1274

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD-T 1015
            L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC    
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334

Query: 1016 VAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1073
            V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G  
Sbjct: 1335 VVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGLQ 1392

Query: 1074 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYC 1106
               CT ++     C   G  V  WR+P+ CP+ C
Sbjct: 1393 HLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 59/251 (23%), Positives = 92/251 (36%), Gaps = 23/251 (9%)

Query: 634  LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----SC----- 684
            L + +P   +    G+CG++N++ ED+ M   + +  +   F NSW+      SC     
Sbjct: 2053 LEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLV 2112

Query: 685  --------PKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTC 736
                     + NPS        + A   C   L  +   A C   ++  P+  +C    C
Sbjct: 2113 DEQQIPAEQQENPSGNCRAADLRRAREKCEAAL-RAPVWAQCASRIDLTPFLVDCANTLC 2171

Query: 737  TCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKACNSSCRSL 795
                    LC  L  +   C  +      WR +  C   CP+   +   + +C+ SC  L
Sbjct: 2172 EFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDL 2231

Query: 796  SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD---N 852
              R     V     +GC C    Y  +E  CV +SQC C        P     +      
Sbjct: 2232 DGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTE 2290

Query: 853  KCVCRDGILLC 863
            KCVC  G + C
Sbjct: 2291 KCVCTGGAIQC 2301



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 35/144 (24%), Positives = 59/144 (40%), Gaps = 27/144 (18%)

Query: 636  VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
            +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513

Query: 690  ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                              S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 2573

Query: 732  KKYTCTCEN---SQDCLCTILGNY 752
                C+ ++    ++  C +L  +
Sbjct: 2574 VLDLCSAQDPREQEELRCQVLSGH 2597



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 26/149 (17%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 2434 LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 2491

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 2492 TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 2550

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEACA 1066
             D    F  CH  V P  + + C+ + C+
Sbjct: 2551 ADPQGPFAACHQTVAPEPFQEHCVLDLCS 2579



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 30/110 (27%), Positives = 46/110 (41%), Gaps = 11/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1752 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1806

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C   RCP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1807 FC-PMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 14/38 (36%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 562  TQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 599
            T+RCP    Y+ C  + PA+C +  P     C  GC C
Sbjct: 1041 TERCPPNARYESC--ACPASCKSPRPSCGPLCREGCVC 1076



>gi|4321127|gb|AAD15624.1|   IgG Fc binding protein [AA 4671-5405] [Homo sapiens]
          Length = 735

 Score =  133 bits (334), Expect = 2e-30
 Identities = 121/486 (24%), Positives = 184/486 (37%), Gaps = 87/486 (17%)

Query: 711  SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-G 769
            + GPLA CH +V P  Y + C    C  +     LC  +  YV AC      +  WR   
Sbjct: 4    TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD 63

Query: 770  LCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 829
             C   CP+   ++    +C  SC SLS  +     E    +GC C DA +  +   CV  
Sbjct: 64   FCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCESACREGCVC-DAGFVLSGDTCVPV 119

Query: 830  SQCDC------YINDEVMQPGKLI----------HID---------DNKCVCRDGILLCQ 864
             QC C      Y   EV  PG             H+            +C   DG+  C 
Sbjct: 120  GQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACH 179

Query: 865  ---------------IPIDLTLQNCSGGAEYV--DCSDPKAQRRTNRTCSTRNIPVFDDQ 907
                           I +D  + +  G   YV      PK           +N      +
Sbjct: 180  ATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR 239

Query: 908  NIVLQDGKVTAVKSTESKKCELNANAYSIHT-------VGLYLILKFQNGIIVIWDKNTR 960
             +V   G+V ++   +    +  A A  +          G  ++L+   G+ +++D +  
Sbjct: 240  LLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAH 299

Query: 961  LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD--- 1014
            L + +   + G++CGLCGN NG+  DDF     S AS    FG +W+   +S+ C +   
Sbjct: 300  LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 359

Query: 1015 -------TVAQTFPCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEAC 1065
                      +T P +SN          C  LR+    F  C   + PS Y   C+ + C
Sbjct: 360  PQGCPVCLAEETAPYESN--------EACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLC 411

Query: 1066 ACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGT 1124
            A   +G     C ++A Y  AC A GV V  WR  + CP++C  ++       HY  C  
Sbjct: 412  A--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYSICTR 462

Query: 1125 VTAKTC 1130
                +C
Sbjct: 463  TCQGSC 468



 Score = 98.2 bits (243), Expect = 9e-20
 Identities = 95/422 (22%), Positives = 158/422 (37%), Gaps = 75/422 (17%)

Query: 634 LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-----N 688
           L +S+P        GLCG++N    DDF+        + + F  +W      KG      
Sbjct: 300 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 359

Query: 689 PSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDC 744
           P  C     E+ A       CG L +  GP A+C  +++P  Y  +C    C  +  +  
Sbjct: 360 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 419

Query: 745 LCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCD 803
           LC  L  Y  AC      +  WRT   C   CP+   +    + C  SC +LS     C 
Sbjct: 420 LCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLT-GCT 478

Query: 804 VEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQ--------------------- 842
                 +GC C D  +  ++G C+    C C  N   +                      
Sbjct: 479 TRCF--EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSG 535

Query: 843 ---------PGKLIHI--DDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRR 891
                    PG++  +  +   C    G+ +  +  +LT  + + GA     + P     
Sbjct: 536 LTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGAT----TSPGVYEL 591

Query: 892 TNRTCSTRN-IPVF----------------DDQNIVLQDGKVTAVKS----TESKKCELN 930
           ++R    +N IP +                   +I  QDG VT   +        + +L 
Sbjct: 592 SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP 651

Query: 931 ANAYSIHTVGLY----LILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKD 986
           A   +  +V       L+++ + G+ V    N +++VI+  +  GK+CG CGN +GD  +
Sbjct: 652 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 711

Query: 987 DF 988
           D+
Sbjct: 712 DW 713



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 7/86 (8%)

Query: 517 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 575
           C+ + CQ +      C   +     C + G    E  R D    C  Q CP    Y+ CG
Sbjct: 24  CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 79

Query: 576 PSNPATCSNVAPFQ--DSECVSGCTC 599
            S P +C +++  +  +S C  GC C
Sbjct: 80  DSCPVSCPSLSAPEGCESACREGCVC 105



>gi|553810|gb|AAA61295.1|   von Willebrand factor
          Length = 958

 Score =  129 bits (325), Expect = 3e-29
 Identities = 66/170 (38%), Positives = 86/170 (50%), Gaps = 12/170 (7%)

Query: 972  KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1031
            KVCGLCGN +G   +D T+    V    ++FGNSWK S +C+DT  +  P DS+P     
Sbjct: 2    KVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADT--RKVPLDSSPATCHN 59

Query: 1032 AVRK-------CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYA 1084
             + K       C IL    F+DC+  VDP  Y DVCI + C+C+  G    FC  +A YA
Sbjct: 60   NIMKQTMVDSSCRILTSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYA 119

Query: 1085 EACSAVGVCVSWRKPNLCPVYCDYYNAPG---ECRWHYEPCGTVTAKTCK 1131
              C+  G  V+WR   LCP  C+  N      EC W Y  C      TC+
Sbjct: 120  HVCAQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQ 169



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 35/253 (13%)

Query: 648 GLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPK-------GNPSSCIS-IEKE 698
           GLCG+++    +D  SS   +E+    F NSW++ S C          +P++C + I K+
Sbjct: 5   GLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQ 64

Query: 699 KFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTILGNYVKAC 756
              +  C IL  +S     C+ +V+P+PY + C   TC+CE+  D  C C  +  Y   C
Sbjct: 65  TMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 122

Query: 757 AEKETYIVGWRTG-LCEHSC------PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 809
           A+    +V WRT  LC  SC       +G   ++   +C  +C+   +           V
Sbjct: 123 AQ-HGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCV 181

Query: 810 DGCTC---PDAMYQNNEGNCVLKSQCD-CYINDEVMQPGKLIHI---DDNKC-VCRDGIL 861
           +GC     P  +       CV    C  C +       GK + +   D   C +C     
Sbjct: 182 EGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICH---- 237

Query: 862 LCQIPIDLTLQNC 874
            C + ++LT + C
Sbjct: 238 -CDV-VNLTCEAC 248



>gi|3135306|gb|AAC78790.1|   zonadhesin [Homo sapiens]
          Length = 2379

 Score =  122 bits (307), Expect = 3e-27
 Identities = 126/539 (23%), Positives = 202/539 (37%), Gaps = 85/539 (15%)

Query: 644  TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPK-------GNPSSCISIE 696
            T +  + G+YNN + DD +     L   S     +W++    +       G PSSC    
Sbjct: 1607 TMSTRVTGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENS 1666

Query: 697  KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 756
                  ++C IL++  GP + CH +V P+     C    C  +     LC  L  Y   C
Sbjct: 1667 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1726

Query: 757  AEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSE-RD--------RSCDVED- 806
            A+       WR       CP G  +      C  +C S++  RD         SC+ +  
Sbjct: 1727 AQ-AGQAPAWRNRTFCRECPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKG 1785

Query: 807  --------VPVD--GCTCPDAMYQ------NNEGNCVLKSQCDCYIN----DEVMQPGKL 846
                    VP+   GCT P   Y         E  C     C  + N        +P ++
Sbjct: 1786 HILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQI 1845

Query: 847  IHIDDNKCVCR-DGILLCQIPIDLTLQNCSGGAEYVD--CS------------------D 885
                D    CR  G+ +CQ+P +    +  G    +   C+                   
Sbjct: 1846 CWALDGLLHCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPLFKIS 1905

Query: 886  PKAQRRTNRTCSTRNIPVFDDQ---NIVLQDGKVTAVKSTESKKCELN-ANAYSIHTVGL 941
             K ++    T + R   V+ D     + LQ G    + S +     ++     S+ +  +
Sbjct: 1906 AKHEKEEGGTEAFRLHEVYIDMYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSI 1965

Query: 942  YLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD-FTTRYSSVASGAL 1000
            Y I+  + G+ V +D N  L + +   + GKVCG+CGN N + +D+        +A+   
Sbjct: 1966 YTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEKLANSDS 2025

Query: 1001 EFGNSWKTSQECSDTVAQTFPCD---------SNP--YCKAWAVR----KCE-ILRDSTF 1044
            EF NSWK      D   Q+ P D          NP   C+A  +R    KCE  LR   +
Sbjct: 2026 EFVNSWKDKD--IDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVW 2083

Query: 1045 RDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLC 1102
              C +++D + +   C      C+  G Y   C A+  +   C + G+    WR  + C
Sbjct: 2084 AQCASRIDLTPFLVDCAN--TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFC 2140



 Score =  112 bits (280), Expect = 4e-24
 Identities = 136/627 (21%), Positives = 224/627 (35%), Gaps = 133/627 (21%)

Query: 609  ASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNIL 668
            AS  +++++T F   L+++     QLYV++         GLCG+Y+  +++D +      
Sbjct: 1163 ASGRFVELQTEFG--LRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSP 1220

Query: 669  EKTSQAFANSW-----EMMSCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCH 719
                +   NSW     E   C K     +PS   S++        CG L+D+ GP  +C 
Sbjct: 1221 AGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCL 1280

Query: 720  PIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWR-TGLCEH---SC 775
              V    + + C    C  +  Q  LCT +      C +    +  WR    C     +C
Sbjct: 1281 LHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCRELSMAC 1340

Query: 776  PSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQCDC 834
            P    +    K C  +C S       C   D  V+ C C P  +    E  C+ +SQC C
Sbjct: 1341 PPNSKYSLCAKPCPDTCHS-GFSGMFC--SDRCVEACECNPGFVLSGLE--CIPRSQCGC 1395

Query: 835  Y--------INDEVMQPG--KLIHIDDNK--------------CVCRDGILLCQ------ 864
                     + +   +PG  +L   + N               C  +DGI  C       
Sbjct: 1396 LHPAGSYFKVGERWYKPGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAAT 1455

Query: 865  ---------IPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVF-------DDQN 908
                     +  D  L +  G   YV            R C +R+   +       +++ 
Sbjct: 1456 CTASGDPHYLTFDGALHHFMGTCTYV----------LTRPCWSRSQDSYFVVSATNENRG 1505

Query: 909  IVLQDGKVTAVKSTE-------SKKCELNANAYSIH----------TVGL--YLILKFQN 949
             +L+   + AV  T         + C++  N + +           T+ L   L+L + N
Sbjct: 1506 GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTN 1565

Query: 950  -GIIVIWDKNTRLSVILDPNWNGKVCGLC-------------------GNNNGDLKDDFT 989
             G+ V +D +  + + +  ++ G++CGLC                   GN N +  DD  
Sbjct: 1566 FGLQVRYDGSHLVELTVPSSYGGQLCGLCGEFPGHLRGKAGTMSTRVTGNYNNNSLDDNL 1625

Query: 990  TRYSSVASGALEFGNSWKTSQE----CSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDST 1043
                 +A  +++ G +WK  +     C     +   C  N    AW  + C IL      
Sbjct: 1626 RPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAWN-KNCAILINPQGP 1684

Query: 1044 FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCP 1103
            F  CH  V P +    C+   C    +G     C ++  YA  C+  G   +WR    C 
Sbjct: 1685 FSQCHQVVPPQSSFASCVHGQCG--TKGDTTALCRSLQAYASLCAQAGQAPAWRNRTFCR 1742

Query: 1104 VYCDYYNAPGECRWHYEPCGTVTAKTC 1130
                    PG     Y PC +    TC
Sbjct: 1743 EC-----PPGS---SYSPCSSPCPDTC 1761



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 94/391 (24%), Positives = 152/391 (38%), Gaps = 73/391 (18%)

Query: 774  SCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-PDAMYQNNEGNCVLKSQC 832
            SCP     +Y   AC +SC+S      SC    +  +GC C P  ++ +N  +C+  S C
Sbjct: 954  SCPPNA--RYESCACPASCKSPRP---SCG--PLCREGCVCNPGFLFSDN--HCIQASSC 1004

Query: 833  DCYINDEVMQPGKLIHIDD--NKCVCRDGILL-CQIPIDLTLQNCS-------------- 875
            +C  N++  +PG      +    C C  G  + CQI    T   C               
Sbjct: 1005 NCCYNNDYYEPGAKWFTPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGT 1064

Query: 876  ------GGAEYV----------------------DCSDP--------KAQRRTNRTCSTR 899
                  G   YV                      + +DP        + Q +   +C ++
Sbjct: 1065 ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSK 1124

Query: 900  NIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 959
                  +  + L  G+ T V   +     + +    +   G ++ L+ + G+ V WD + 
Sbjct: 1125 VYVTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQ 1184

Query: 960  RLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----SQECSD- 1014
            +L V +   ++GK+CGLCGN +G+  +D      S A    E GNSW+T     QEC   
Sbjct: 1185 QLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKY 1244

Query: 1015 TVAQTFPCDSNPYCKAWAVRKCEILRDS--TFRDCHNKVDPSAYHDVCIEEACACDMEGK 1072
             V  +  CDS+          C  L D+   F  C   V  +++ D C+ + C    +G 
Sbjct: 1245 QVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG--FQGL 1302

Query: 1073 YLGFCTAVAMYAEACSAVGVCVS-WRKPNLC 1102
                CT ++     C   G  V  WR+P+ C
Sbjct: 1303 QHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1333



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 69/313 (22%), Positives = 104/313 (33%), Gaps = 56/313 (17%)

Query: 605  QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDD-F 661
            QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+  
Sbjct: 1954 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 2013

Query: 662  MSSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERH 704
            M S   L  +   F NSW+         S P          + NPS        + A   
Sbjct: 2014 MPSDEKLANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREK 2073

Query: 705  CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIV 764
            C   L  +   A C   ++  P+  +C    C        LC  L  +   C  +     
Sbjct: 2074 CEAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPP 2132

Query: 765  GWRTGLCEHSC-----------PSGLVFKYN--------------------VKACNSSCR 793
             WR     H C           P  L F  +                    + +C+ SC 
Sbjct: 2133 LWRNSSFCHECALLSPQTPPKPPFPLCFPESSLTLLPVPLECPAYSSYTNCLPSCSPSCW 2192

Query: 794  SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD-- 851
             L  R     V     +GC C    Y  +E  CV +SQC C        P     +    
Sbjct: 2193 DLDGRCEGAKVPSACAEGCICQPG-YVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGC 2251

Query: 852  -NKCVCRDGILLC 863
              KCVC  G + C
Sbjct: 2252 TEKCVCTGGAIQC 2264



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 12/110 (10%)

Query: 500  FEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDV 558
            F +C +V    + +   C+   C T+ D T+ C +    + LCA  G     +WR+ +  
Sbjct: 1685 FSQCHQVVPPQSSFAS-CVHGQCGTKGDTTALCRSLQAYASLCAQAGQAP--AWRNRT-- 1739

Query: 559  VCGTQRCPEQHIYKECGPSNPATCSNVAPFQDS----ECVSGCTCPEDKI 604
             C  + CP    Y  C    P TCS++   +D      C   C C +  I
Sbjct: 1740 FC--RECPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1787



>gi|34534638|dbj|BAC87067.1|   unnamed protein product [Homo sapiens]
          Length = 394

 Score =  115 bits (288), Expect = 5e-25
 Identities = 67/223 (30%), Positives = 102/223 (45%), Gaps = 15/223 (6%)

Query: 644 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNP---SSCIS-IE 696
           T   GLCG++    +DDF++    +E +  AFA+ +++     CP  +    S C +  +
Sbjct: 26  TQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQ 85

Query: 697 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 756
           +  FAE  C IL   S     CH +V+ +P++  C    C C+   DCLC +L  Y + C
Sbjct: 86  RHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRC 143

Query: 757 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 815
           A+ E     WR   LC   CP G  ++    AC   C     +   C      V GC CP
Sbjct: 144 AQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC----GKPEDCGELGSCVAGCNCP 198

Query: 816 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRD 858
             +  + EG CV  S C C +      PG     + N+C+C++
Sbjct: 199 LGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQE 241



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 12/162 (7%)

Query: 972  KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE--C-SDTVAQTFPCDSNPYC 1028
            +V GLCG    + +DDF T    V +    F + ++ + +  C S+  A   PC ++   
Sbjct: 27   QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 86

Query: 1029 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1088
             A+A   C IL  S F++CH  VD   ++  C+   C CD     L  C  ++ YA  C+
Sbjct: 87   HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL--CPVLSAYARRCA 144

Query: 1089 AVGVCVSWRKPNLCPVYC----DYYNAPGECRWHY---EPCG 1123
              G    WR   LCPV C    +Y      C  H    E CG
Sbjct: 145  QEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCG 186



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 472 GDCPNAVGKSYEVCEDGIQH-------CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQT 524
           G CP+        C    Q        C  +  + F++C ++      Y + C+   C  
Sbjct: 67  GRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY-LRCLAAVCGC 125

Query: 525 RDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
              +   C   S  +R CA +G      WR+ +  +C    CP    Y+EC P+    C 
Sbjct: 126 DPGSDCLCPVLSAYARRCAQEGASP--PWRNQT--LCPVM-CPGGQEYRECAPACGQHCG 180

Query: 584 NVAPFQD-SECVSGCTCP 600
                 +   CV+GC CP
Sbjct: 181 KPEDCGELGSCVAGCNCP 198



>gi|34535476|dbj|BAC87330.1|   unnamed protein product [Homo sapiens]
          Length = 1508

 Score =  114 bits (286), Expect = 9e-25
 Identities = 59/170 (34%), Positives = 88/170 (51%), Gaps = 4/170 (2%)

Query: 936  IHT--VGLYLILKF-QNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 992
            +HT  VG + ++ F Q  I ++WD+ T + V   P W G++ GLCGN +    ++  T  
Sbjct: 86   VHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 145

Query: 993  SSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVD 1052
            +   +   EFG+SW  + EC DT+     C  NP  + +A ++C IL    F  CH  VD
Sbjct: 146  NLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVD 204

Query: 1053 PSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLC 1102
             + ++  C+ + C C   G    FC +V+ YA  C   GV V WR P LC
Sbjct: 205  VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 254



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 20/167 (11%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1031
            GLCG  +GD  +D T +  SV  GA +   F +SW+     +      F  DS   C   
Sbjct: 1253 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 1309

Query: 1032 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1089
                C  ++ + TF  CH  V P ++ ++ I +        KY+   C A+ +Y   C  
Sbjct: 1310 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 1362

Query: 1090 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG 1136
              VC+ WR+ + CP  C   +    C    EP      KTC+D ++G
Sbjct: 1363 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILG 1404



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 8/140 (5%)

Query: 634 LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-NPSSC 692
           ++V   P       GLCG+++ K  ++  + +N+     Q F +SW  + CP   +P   
Sbjct: 114 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDM 173

Query: 693 ISIE--KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTI 748
             +   +E FA++ C ILL  S     CHP+V+   ++  C   TC C    D  C C  
Sbjct: 174 CVLNPLREPFAKKECSILL--SEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCAS 231

Query: 749 LGNYVKACAEKETYIVGWRT 768
           +  Y   C +     V WRT
Sbjct: 232 VSAYAHQCCQ-HGVAVDWRT 250



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 51/237 (21%), Positives = 91/237 (38%), Gaps = 37/237 (15%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERH 704
            GLCG  +  A +D       +   ++    F +SW++       PSS  S+ + +F    
Sbjct: 1253 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDS 1305

Query: 705  CG-------ILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 757
            C        + + S+   ++CH  V P+ + E   + T   +      C  L  YV  C 
Sbjct: 1306 CATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCH 1361

Query: 758  EKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCP 815
            +    I   R+  C   C S   ++  V AC              D E   V  +GC C 
Sbjct: 1362 KFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCS 1421

Query: 816  DA--MYQNNEGNCVLKSQC---DCYINDEVMQPGKLIHIDDN---------KCVCRD 858
            +   +++ +   C+ +++C   DC  +    Q G+ + +  N         +CVC +
Sbjct: 1422 EGTILHRRHSALCIPEAKCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCEN 1478



>gi|42659821|ref|XP_291816.4|   PREDICTED: otogelin [Homo sapiens]
          Length = 1508

 Score =  114 bits (286), Expect = 9e-25
 Identities = 59/170 (34%), Positives = 88/170 (51%), Gaps = 4/170 (2%)

Query: 936  IHT--VGLYLILKF-QNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 992
            +HT  VG + ++ F Q  I ++WD+ T + V   P W G++ GLCGN +    ++  T  
Sbjct: 86   VHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPE 145

Query: 993  SSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVD 1052
            +   +   EFG+SW  + EC DT+     C  NP  + +A ++C IL    F  CH  VD
Sbjct: 146  NLELTNPQEFGSSW-AAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVD 204

Query: 1053 PSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLC 1102
             + ++  C+ + C C   G    FC +V+ YA  C   GV V WR P LC
Sbjct: 205  VTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLC 254



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 48/167 (28%), Positives = 73/167 (43%), Gaps = 20/167 (11%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALE---FGNSWKTSQECSDTVAQTFPCDSNPYCKAW 1031
            GLCG  +GD  +D T +  SV  GA +   F +SW+     +      F  DS   C   
Sbjct: 1253 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS---CATT 1309

Query: 1032 AVRKC-EILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF-CTAVAMYAEACSA 1089
                C  ++ + TF  CH  V P ++ ++ I +        KY+   C A+ +Y   C  
Sbjct: 1310 DCSPCLRMVSNRTFSACHRFVPPESFCELWIRDT-------KYVQQPCVALTVYVAMCHK 1362

Query: 1090 VGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVG 1136
              VC+ WR+ + CP  C   +    C    EP      KTC+D ++G
Sbjct: 1363 FHVCIEWRRSDYCPFLCSSDSTYQACVTACEP-----PKTCQDGILG 1404



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 40/140 (28%), Positives = 63/140 (45%), Gaps = 8/140 (5%)

Query: 634 LYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-NPSSC 692
           ++V   P       GLCG+++ K  ++  + +N+     Q F +SW  + CP   +P   
Sbjct: 114 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDM 173

Query: 693 ISIE--KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD--CLCTI 748
             +   +E FA++ C ILL  S     CHP+V+   ++  C   TC C    D  C C  
Sbjct: 174 CVLNPLREPFAKKECSILL--SEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCAS 231

Query: 749 LGNYVKACAEKETYIVGWRT 768
           +  Y   C +     V WRT
Sbjct: 232 VSAYAHQCCQ-HGVAVDWRT 250



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 51/237 (21%), Positives = 91/237 (38%), Gaps = 37/237 (15%)

Query: 648  GLCGSYNNKAEDDFMSSQNILEKTSQ---AFANSWEMMSCPKGNPSSCISIEKEKFAERH 704
            GLCG  +  A +D       +   ++    F +SW++       PSS  S+ + +F    
Sbjct: 1253 GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQV-------PSSLTSVGQTRFRPDS 1305

Query: 705  CG-------ILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 757
            C        + + S+   ++CH  V P+ + E   + T   +      C  L  YV  C 
Sbjct: 1306 CATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCH 1361

Query: 758  EKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV--DGCTCP 815
            +    I   R+  C   C S   ++  V AC              D E   V  +GC C 
Sbjct: 1362 KFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCS 1421

Query: 816  DA--MYQNNEGNCVLKSQC---DCYINDEVMQPGKLIHIDDN---------KCVCRD 858
            +   +++ +   C+ +++C   DC  +    Q G+ + +  N         +CVC +
Sbjct: 1422 EGTILHRRHSALCIPEAKCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCEN 1478



>gi|37360934|dbj|BAC98376.1|   KIAA2036 protein [Homo sapiens]
          Length = 1322

 Score =  114 bits (284), Expect = 2e-24
 Identities = 58/183 (31%), Positives = 87/183 (47%), Gaps = 7/183 (3%)

Query: 951  IIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ 1010
            ++ +    TR+ V L P + G+V GLCG+ +GD  +D  +R   +   A    +SW+ S 
Sbjct: 6    LLTMLPPGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP 65

Query: 1011 ECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDME 1070
             C +      PC  N +   WA  +C  L    F  CH +V P  +++ C+ +AC CD  
Sbjct: 66   LCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSG 125

Query: 1071 GKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
            G     C+A+A YA+ C+  G  V WR   LC + C+           YE CG     TC
Sbjct: 126  GDCECLCSAIATYADECARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTC 178

Query: 1131 KDQ 1133
             +Q
Sbjct: 179  HEQ 181



 Score =  106 bits (265), Expect = 2e-22
 Identities = 72/248 (29%), Positives = 111/248 (44%), Gaps = 13/248 (5%)

Query: 624 LQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS 683
           L   + P  ++ V + P       GLCG ++  A +D  S Q +LE T++  A+SW +  
Sbjct: 6   LLTMLPPGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSP 65

Query: 684 -CPKGN--PSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCE 739
            CP+    P  C ++  +  +A   CG LL     L  CH  V P+ ++E C    C C+
Sbjct: 66  LCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCD 123

Query: 740 NSQD--CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSL- 795
           +  D  CLC+ +  Y   CA +  + V WR+  LC   C  G V++     C  +C    
Sbjct: 124 SGGDCECLCSAIATYADECA-RHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQH 182

Query: 796 SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCV 855
            E    C V    V+GC CP+    +  G C+  + C C        PG ++  D   C 
Sbjct: 183 PEPGWHCQVV-ACVEGCFCPEGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 240

Query: 856 CRDGILLC 863
           C++G   C
Sbjct: 241 CQEGQWHC 248



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 38/89 (42%)

Query: 771 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
           C ++  SG +       C  +C  +S +            GC CP+     +EG CV   
Sbjct: 815 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPR 874

Query: 831 QCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
           QC C ++     PG+ I  D   C+C+DG
Sbjct: 875 QCPCLVDGARYWPGQRIKADCQLCICQDG 903



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 14/139 (10%)

Query: 471 PGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYC---QTRDK 527
           PGD P+    +          C  ++   F  C         Y+  C+ + C      D 
Sbjct: 70  PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEW-CLYDACGCDSGGDC 128

Query: 528 TSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAP 587
              C   +  +  CA  G      WRS    +C  Q C    +Y+ CGP+ P TC    P
Sbjct: 129 ECLCSAIATYADECARHGHHV--RWRSQE--LCSLQ-CEGGQVYEACGPTCPPTCHEQHP 183

Query: 588 -----FQDSECVSGCTCPE 601
                 Q   CV GC CPE
Sbjct: 184 EPGWHCQVVACVEGCFCPE 202



>gi|51105836|gb|EAL24436.1|   KIAA2036 protein [Homo sapiens]
          Length = 1314

 Score =  113 bits (283), Expect = 2e-24
 Identities = 58/175 (33%), Positives = 84/175 (48%), Gaps = 7/175 (4%)

Query: 959  TRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1018
            TR+ V L P + G+V GLCG+ +GD  +D  +R   +   A    +SW+ S  C +    
Sbjct: 6    TRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDL 65

Query: 1019 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1078
              PC  N +   WA  +C  L    F  CH +V P  +++ C+ +AC CD  G     C+
Sbjct: 66   PHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCS 125

Query: 1079 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQ 1133
            A+A YA+ C+  G  V WR   LC + C+           YE CG     TC +Q
Sbjct: 126  AIATYADECARHGHHVRWRSQELCSLQCEGGQV-------YEACGPTCPPTCHEQ 173



 Score =  106 bits (264), Expect = 3e-22
 Identities = 71/242 (29%), Positives = 109/242 (45%), Gaps = 13/242 (5%)

Query: 630 PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-CPKGN 688
           P  ++ V + P       GLCG ++  A +D  S Q +LE T++  A+SW +   CP+  
Sbjct: 4   PGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPG 63

Query: 689 --PSSC-ISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD-- 743
             P  C ++  +  +A   CG LL     L  CH  V P+ ++E C    C C++  D  
Sbjct: 64  DLPHPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCE 121

Query: 744 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSL-SERDRS 801
           CLC+ +  Y   CA +  + V WR+  LC   C  G V++     C  +C     E    
Sbjct: 122 CLCSAIATYADECA-RHGHHVRWRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWH 180

Query: 802 CDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGIL 861
           C V    V+GC CP+    +  G C+  + C C        PG ++  D   C C++G  
Sbjct: 181 CQVV-ACVEGCFCPEGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQW 238

Query: 862 LC 863
            C
Sbjct: 239 HC 240



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 25/89 (28%), Positives = 38/89 (42%)

Query: 771 CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKS 830
           C ++  SG +       C  +C  +S +            GC CP+     +EG CV   
Sbjct: 807 CPNATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPR 866

Query: 831 QCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
           QC C ++     PG+ I  D   C+C+DG
Sbjct: 867 QCPCLVDGARYWPGQRIKADCQLCICQDG 895



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 37/139 (26%), Positives = 50/139 (35%), Gaps = 14/139 (10%)

Query: 471 PGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCGKVAALSNDYKMICIDEYC---QTRDK 527
           PGD P+    +          C  ++   F  C         Y+  C+ + C      D 
Sbjct: 62  PGDLPHPCTMNTHRAGWARARCGALLQPLFTLCHAEVPPQQHYEW-CLYDACGCDSGGDC 120

Query: 528 TSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAP 587
              C   +  +  CA  G      WRS    +C  Q C    +Y+ CGP+ P TC    P
Sbjct: 121 ECLCSAIATYADECARHGHHV--RWRSQE--LCSLQ-CEGGQVYEACGPTCPPTCHEQHP 175

Query: 588 -----FQDSECVSGCTCPE 601
                 Q   CV GC CPE
Sbjct: 176 EPGWHCQVVACVEGCFCPE 194



>gi|4322670|gb|AAD16120.1|   dentin phosphoryn [Homo sapiens]
          Length = 788

 Score =  110 bits (275), Expect = 2e-23
 Identities = 107/454 (23%), Positives = 172/454 (37%), Gaps = 15/454 (3%)

Query: 23  ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
           +S S   S  S SS   D      S       ++ D S   + + S  S D+ +    +S
Sbjct: 197 SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 256

Query: 83  SSS-SGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDK 141
           S+S S DSD +    S        + D S  S  +  S S D+        SS S DS  
Sbjct: 257 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 316

Query: 142 KKPLFSFEFGATGEDEDKSRERWDAGNSR--SEDSPAVGTGSSGLKLGAGKGDAAFGFEV 199
                     +   D   S +  D+ NS   S+ S +  + SS     +   D++     
Sbjct: 317 SSNSSDSNDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSCNS 376

Query: 200 SDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQ 259
           SDS+   D+   S +   N++ SS  S S D  D+S  S++        N  SN  DS  
Sbjct: 377 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS--DSSDSNESSNSSDSSD 434

Query: 260 EGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGS 319
                +    +  + S S+++      S+SS+S + S   +         +  +   S S
Sbjct: 435 SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 494

Query: 320 NQSGDNGNSSKDFDGNGVGDSSARNGFENS----------SGISEDSGVILGSSDQHEVE 369
           + S D+ NSS   D N    S +    ++S          S  S DS     SSD  +  
Sbjct: 495 SNSSDSSNSSDSSDSNSSDSSDSSXSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 554

Query: 370 LSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEF 429
            S   GN   SSD  ++ + S  SD SDS  ++ SSDS        + +    +   +  
Sbjct: 555 NSSDSGNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 614

Query: 430 GETGLSGSEKGSHIPEATPKYSETNAIIGQDINE 463
             +  S S   S   +++     +N+    D ++
Sbjct: 615 ESSDSSDSSDSSDSSDSSDSSESSNSSDSSDSSD 648



 Score =  106 bits (265), Expect = 2e-22
 Identities = 115/452 (25%), Positives = 175/452 (38%), Gaps = 12/452 (2%)

Query: 23  ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
           +S S   +  S+SS   D      S       ++ D S       S  S  + +    NS
Sbjct: 317 SSNSSDSNDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSCNS 376

Query: 83  SSSSGDSDRT--KPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSD 140
           S SS  SD +      S        + D S  S  +  S S D+        SS S DS 
Sbjct: 377 SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 436

Query: 141 KKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVS 200
                 S +   + +  D S     + +S S D+    + SS     +   D++     S
Sbjct: 437 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN----SNSSDSSNSSDSSDSSDSSNSS 492

Query: 201 DSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQE 260
           DS++  D+  SS + + N + SS  S S D  D+S  S++      S +S S+  DS   
Sbjct: 493 DSSNSSDSSNSSDSSDSNSSDSSDSSXSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDS 550

Query: 261 GFGINEI-GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGS 319
               N    GN    S S+++      SDSS S + S   +         +  +   S S
Sbjct: 551 SDSSNSSDSGNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 610

Query: 320 NQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKR 379
           + S ++ +SS   D +   DSS  +   NSS  S DS     SSD  +   S    NR  
Sbjct: 611 SDSSESSDSSDSSDSSDSSDSSDSSESSNSSD-SSDSSDSSDSSDSSDSSDSSDSSNRSD 669

Query: 380 SSDPDEAGNLSPGSDVSDSGGNTWSSDS--GSGGGGKSADELGVGASGLNEFGETGLSGS 437
           SSD  ++ + S  SD SDS  ++ SSDS   S     S       +S  NE  ++  S  
Sbjct: 670 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 729

Query: 438 EKGSHIPEATPKYSETNAIIGQDINEHIANSK 469
              S     +   S+++       +E  + SK
Sbjct: 730 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 761



 Score =  101 bits (252), Expect = 8e-21
 Identities = 105/446 (23%), Positives = 166/446 (37%), Gaps = 22/446 (4%)

Query: 18  DGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
           D   +++ +   S  S+SS   D      S +      + D S     + S  S D+   
Sbjct: 252 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 311

Query: 78  GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
              + SS+S DS+ +         +       S DS D+  S   D+        SS S 
Sbjct: 312 SDSSDSSNSSDSNDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 371

Query: 138 DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGF 197
           DS            + G D D S  R D+ NS      +  + SS     +   +++   
Sbjct: 372 DSCNSSDSSDSSDSSDGSDSDSSN-RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 430

Query: 198 EVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
           + SDS++  D+  S  +   N + SS  S S D  ++S  S+N      + +  SN  DS
Sbjct: 431 DSSDSSNSSDSDSSDSS---NSSDSSDSSNSSDSSESSNSSDNS-----NSSDSSNSSDS 482

Query: 258 GQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                  N    +  S S ++        SDSS S   S             +  +   S
Sbjct: 483 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSXSS------------DSSDSSDSS 530

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
            S+ S D+ +SS   D +   DSS  +   NSS  S DS     SSD  +   S    N 
Sbjct: 531 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSGNSSD-SSDSSDSSDSSDSSDSSDSSDSSNS 589

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGS 437
             SSD  ++ + S  SD SDS  ++ SSDS        + +    +   N    +  S S
Sbjct: 590 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSESSNSSDSSDSSDS 649

Query: 438 EKGSHIPEATPKYSETNAIIGQDINE 463
              S   +++     +N     D ++
Sbjct: 650 SDSSDSSDSSDSSDSSNRSDSSDSSD 675



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 104/404 (25%), Positives = 160/404 (39%), Gaps = 23/404 (5%)

Query: 30  SYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDS 89
           S  SS   D D      S       ++ D S     + S  S ++      + SS+S DS
Sbjct: 382 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 441

Query: 90  DRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFE 149
           D +    S        + D S  S  +  S S D         SS+S DS       +  
Sbjct: 442 DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD---------SSNSSDSSDSSDSSNSS 492

Query: 150 FGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTG 209
             +   D   S +  D+ +S S DS +  + SS     +   D++   + SDS+   D+ 
Sbjct: 493 DSSNSSDSSNSSDSSDSNSSDSSDS-SXSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 551

Query: 210 ISSKTVE-GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIG 268
            SS + + GN + SS  S S D  D+S  S++      S +S S+  DS       +   
Sbjct: 552 DSSNSSDSGNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS--DSSD-----SSDS 604

Query: 269 GNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 328
            +    S S+E+      SDSS S + S   E         +  +   S S+ S D+ +S
Sbjct: 605 SDSSDSSDSSESSDSSDSSDSSDSSDSSDSSESSNSSDSSDSSDSSDSSDSSDSSDSSDS 664

Query: 329 SKDFDGNGVGDSSARNGFENSSGISE-----DSGVILGSSDQHEVELSRTGGNRKRSSDP 383
           S   D +   DSS  +   +SS  S+     DS     SSD  +   S    +   SSD 
Sbjct: 665 SNRSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 724

Query: 384 DEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLN 427
            ++ + S  S+ SDS  ++ SSDS S    +S  +   G    N
Sbjct: 725 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 768



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 116/447 (25%), Positives = 179/447 (40%), Gaps = 24/447 (5%)

Query: 18  DGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
           D   + S     S  SS S D D      S +  S       S     + S  S D+   
Sbjct: 86  DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 145

Query: 78  GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
              + SS S DS  +K   S        ++ KS DS D+  S S D         SS+S 
Sbjct: 146 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS-DSSDSNSSDSSDNSDSSDSSNSSNSS 204

Query: 138 DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGF 197
           DS            +   +   S +  D+ NS SE S +  +  S         D++   
Sbjct: 205 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS-SESSDSSDSSDS---------DSSDSS 254

Query: 198 EVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
           + S+SNS  D+  S+ +   + ++SS  S S D  ++S  S++      S +S S+  DS
Sbjct: 255 DSSNSNS-SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS--DS 311

Query: 258 GQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAE-FNFRD 316
                  N    N  S S  +++      SDSS+S + S   +    ++   ++  N  D
Sbjct: 312 SDSSDSSNSSDSNDSSNS--SDSSDSSDSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 369

Query: 317 SG-SNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           S  S  S D+ +SS   DG+   DSS R+   NSS  S DS     SSD  +   S    
Sbjct: 370 SSDSCNSSDSSDSSDSSDGSD-SDSSNRSDSSNSSD-SSDSSDSSNSSDSSDSSDSNESS 427

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLS 435
           N   SSD  ++ N S  SD SDS  ++ SSDS +      +      ++  +    +  S
Sbjct: 428 N---SSDSSDSSN-SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 483

Query: 436 GSEKGSHIPEATPKYSETNAIIGQDIN 462
            S   S+  +++     +N+    D N
Sbjct: 484 DSSDSSNSSDSSNSSDSSNSSDSSDSN 510



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 103/403 (25%), Positives = 161/403 (39%), Gaps = 20/403 (4%)

Query: 24  SRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSS 83
           S S   S  S+SS   D      S +     ++ + S     + S  S D+ +    NSS
Sbjct: 391 SDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 450

Query: 84  SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
            SS  S+ +    S        + D S  S  +  S S ++        SS+S DS    
Sbjct: 451 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 510

Query: 144 PLFSFEFGATGEDEDKSRERWDAGNSRSEDSP--AVGTGSSGLKLGAGKGDAAFGFEVSD 201
              S +   + +  D S     + +S S DS   +  + SS     +  G+++   + SD
Sbjct: 511 SSDSSDSSXSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSGNSSDSSDSSD 570

Query: 202 SNSFGDTGISSKTVEG-NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQE 260
           S+   D+  SS + +  N + SS  S S D  D+S  S++      S +S S+      +
Sbjct: 571 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSD 630

Query: 261 GFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSN 320
               +E   N    S S+++      SDSS S + S          +  +  +   S S+
Sbjct: 631 SSDSSE-SSNSSDSSDSSDSSDSSDSSDSSDSSDSS---------NRSDSSDSSDSSDSS 680

Query: 321 QSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRS 380
            S D+ +SS   D +   DSS  +   +SS  S DS     SSD  +   S    N   S
Sbjct: 681 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD-SSDSSDSNESSDSSDSSDSSDSSNSSDS 739

Query: 381 SD-PDEAGNLSPGSDVSDS-----GGNTWSSDSGSGGGGKSAD 417
           SD  D + + S  +D SDS      GN   SDS S   G  ++
Sbjct: 740 SDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 782



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 100/414 (24%), Positives = 156/414 (37%), Gaps = 38/414 (9%)

Query: 33  SSSSGDLDRKKPLFSLEFGSPGETEDKSRQR---QDAGSPKSEDTPAGGFFNSSSSSGDS 89
           S+ + D + +    S   G      D+S+      D+   + +D+ +    N+S S+G+ 
Sbjct: 9   SNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNG 68

Query: 90  DRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFE 149
           +             GK++    DS D+  S             S+SS DSD      S  
Sbjct: 69  NNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 128

Query: 150 FGATGEDEDKSRERWDAGNSR--SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGD 207
             +   D   S +  D+ +S   S+ S +  + S   K  +   D+    + SDSNS   
Sbjct: 129 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 188

Query: 208 TGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEI 267
           +  S  +   N ++SS  S S D  D+S  S++           SN  DS       N  
Sbjct: 189 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS-----------SNSSDSSDSSDSSNSS 237

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
             +  S S  +++      S+S+SS   S                    S S+ S ++ +
Sbjct: 238 ESSDSSDSSDSDSSDSSDSSNSNSSDSDS-----------------SNSSDSSDSSNSSD 280

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
           SS   D +   DSS  +   NSS  S DS     SSD      S    N   SSD  ++ 
Sbjct: 281 SSDSSDSSNSSDSSDSSDSSNSSD-SSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSDSS 339

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           + S  SD SDS  ++ S  S S     S+D     +   N    +  S S  GS
Sbjct: 340 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSD----SSDSCNSSDSSDSSDSSDGS 389



 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 95/373 (25%), Positives = 146/373 (39%), Gaps = 15/373 (4%)

Query: 30  SYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDS 89
           S  SS S D        S +  +  ++ D S     + S  S D       NSS SS  S
Sbjct: 426 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNS-----NSSDSSNSS 480

Query: 90  DRTKPFFSLGLGAPGKAEDKSG--DSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFS 147
           D +    S        + D S   DS D+  S S D+        SS S DS        
Sbjct: 481 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSXSSDSSDSSDSSDSSDSSDSSD 540

Query: 148 FEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGD 207
               +   D   S    D+GNS      +  + SS     +   D++   + SDS+   D
Sbjct: 541 SSDSSDSSDSSDSSNSSDSGNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 600

Query: 208 TGISSKTVEGNQTS-SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE 266
           +  SS + + + +S SS  S S D  D+S  S++      S +S S+  DS       + 
Sbjct: 601 SSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSESSNSSDSSDSS--DSSDSSDSSDS 658

Query: 267 IGGNGMSG-SVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDN 325
              +  S  S S+++      SDSS S + S   +         +  +   S S+ S D+
Sbjct: 659 SDSSDSSNRSDSSDSSDSSDSSDSSDSSDSS---DSSDSSDSSDSSDSSDSSDSSDSSDS 715

Query: 326 GNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVE-LSRTGGNRKRSSDPD 384
            +S++  D +   DSS  +   +SS  S+ S     S+D+ + +  S  G N    SD D
Sbjct: 716 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 775

Query: 385 EAGNLSPGSDVSD 397
             G+ S  S   D
Sbjct: 776 SEGSDSNHSTSDD 788



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 100/400 (25%), Positives = 160/400 (40%), Gaps = 14/400 (3%)

Query: 23  ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
           +S S   S  S SS   D      S E  +  ++ D S       S  S  + +    NS
Sbjct: 399 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 458

Query: 83  SSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKK 142
           S SS  S+ +    S        + D S  S  +  S S D+        S+SS  SD  
Sbjct: 459 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 518

Query: 143 KPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDS 202
               S +   + +  D S     + +S S DS +  + SS     +   D++   + SDS
Sbjct: 519 XSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSNSSDSGNSSDSSDSSDSSDSSDS 577

Query: 203 NSFGDTGISSKTVEGNQTS-SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEG 261
           +   D+  SS + + + +S SS  S S D  D+S  SE+      S +S S+  DS    
Sbjct: 578 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSS--DSSDSS 635

Query: 262 FGINEIGGNGMSGSV-SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSN 320
              N    +  S S  S+++      SDSS+  + S   +         +  +   S S+
Sbjct: 636 ESSNSSDSSDSSDSSDSSDSSDSSDSSDSSNRSDSSDSSDSSDSSDSSDSSDSSDSSDSS 695

Query: 321 QSGDNGNSSKDFDGNGVGDSSARNGFENSSGI--SEDSGVILGSSDQHEVELSRTGGNRK 378
            S D+ +SS   D +   DSS  N   +SS    S DS     SSD  +   S +  N  
Sbjct: 696 DSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN-- 753

Query: 379 RSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADE 418
                DE+ + S   + +++G ++ S   GS     ++D+
Sbjct: 754 -----DESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 788



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 95/412 (23%), Positives = 156/412 (37%), Gaps = 34/412 (8%)

Query: 152 ATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGI- 210
           A  E ++ S  R DA  + S++S   G GS          D+      SDSN  G+ G  
Sbjct: 15  ANSESDNNSSSRGDASYN-SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 73

Query: 211 -SSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGG 269
            + K+  G   S S  S S D  ++S  S++        NS S+   S  +    ++   
Sbjct: 74  DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSD--S 131

Query: 270 NGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           +    S S+++      SDSS S + S        ++K  +  +  DS  + S  + + S
Sbjct: 132 DSSDSSNSSDSSDSSDSSDSSDSSDSS--------DSKSDSSKSESDSSDSDSKSDSSDS 183

Query: 330 KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
              D +   DSS  +   NSS  S+       SSD  +   S    N   SSD  ++ N 
Sbjct: 184 NSSDSSDNSDSSDSSNSSNSSDSSD-------SSDSSDSSSSSDSSNSSDSSDSSDSSNS 236

Query: 390 SPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPK 449
           S  SD SDS  +  S  S S     S  +    +   +    +  S S   S+  +++  
Sbjct: 237 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 296

Query: 450 YSETNAIIGQDINE-----HIANSKIPGDCPNAVGKSYEVCEDGIQHCNKIIGTYFEKCG 504
              +N+    D ++       +NS    D  N+   S     D     N           
Sbjct: 297 SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS--SDSSDSSN-------SSDS 347

Query: 505 KVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDS 556
             ++ S+D       +   + D + +C++        +SDG  +  S RSDS
Sbjct: 348 SDSSDSSDSDSSNSSDSSNSSDSSDSCNSSDSSDSSDSSDGSDSDSSNRSDS 399



>gi|11036632|ref|NP_055023.1|   dentin sialophosphoprotein preproprotein [Homo sapiens]
 gi|7228476|gb|AAF42472.1|   dentin sialophosphoprotein precursor [Homo sapiens]
 gi|17865470|sp|Q9NZW4|DSPP_HUMAN   Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein
            (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)]
          Length = 1253

 Score =  107 bits (268), Expect = 1e-22
 Identities = 108/413 (26%), Positives = 162/413 (39%), Gaps = 24/413 (5%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
            +S S   S  S SS   D      S       ++ D S   + + S  S D+ +    +S
Sbjct: 665  SSDSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDS 724

Query: 83   SSS-SGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDK 141
            S+S S DSD +    S        + D S  S  +  S S D+        SS S DS  
Sbjct: 725  SNSNSSDSDSSNSSDS------SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778

Query: 142  KKPLFSFEFGATGEDEDKSRERWDAGNSR--SEDSPAVGTGSSGLKLGAGKGDAAFGFEV 199
                      +   D   S    D+ NS   S+ S +  + SS     +   D++     
Sbjct: 779  SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS 838

Query: 200  SDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGS-LNSISNLWDSG 258
            SDS+   D+  SS +   N++ SS  S S D  D+S  S++      S  N  SN  DS 
Sbjct: 839  SDSSDSSDSSDSSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSS 898

Query: 259  QEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSG 318
                  +    +  + S S+++      S+SS+S + S   +         +  +   S 
Sbjct: 899  DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 958

Query: 319  SNQSGDNGNSSKDFDGNGVGDSSARNGFENS-------SGISEDSGVILGSSDQHEVELS 371
            S+ SGD+ NSS   D N    S + N  ++S       S  S DS     SSD  +   S
Sbjct: 959  SSNSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1018

Query: 372  RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSG-------SGGGGKSAD 417
                +   SSD  ++ + S  SD SDS  ++ SSDS        S G   S+D
Sbjct: 1019 SNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSD 1071



 Score =  106 bits (265), Expect = 2e-22
 Identities = 110/445 (24%), Positives = 174/445 (39%), Gaps = 15/445 (3%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
            +S S   S  S+SS   D      S +  +  ++ D S     + S  S D+      + 
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 83   SSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKK 142
            SS S DSD +    S        + D S  S  +  S S D+        S SS  SD  
Sbjct: 812  SSDSSDSDSSN---SSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSDSS 868

Query: 143  KPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDS 202
                S     + +  D S     + +S S DS       S         D++   + SDS
Sbjct: 869  DSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSS--------DSSNSSDSSDS 920

Query: 203  NSFGDTGISSKTVEG-NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEG 261
            ++  D+  SS + +  N + SS  S S D  D+S  S++   G  S +S S+  +S    
Sbjct: 921  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSS 980

Query: 262  FGINEIGGNGMSGSV-SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSN 320
               N    +  S S  S+++      SDSS S + S             +  +   S S+
Sbjct: 981  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDSS 1040

Query: 321  QSGDNGNSSKDFDGNGVGDSSARNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRK 378
             S D+ NSS   D +   DSS  +G  +SS  S+  DS     SSD  +   S    +  
Sbjct: 1041 DSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1100

Query: 379  RSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSE 438
             SSD  ++ + S  SD SDS  ++ SSDS +      + +    +   +    +  S S 
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1160

Query: 439  KGSHIPEATPKYSETNAIIGQDINE 463
              S   +++     +++    D NE
Sbjct: 1161 DSSDSSDSSDSSDSSDSSDSSDSNE 1185



 Score =  106 bits (264), Expect = 3e-22
 Identities = 113/459 (24%), Positives = 177/459 (38%), Gaps = 35/459 (7%)

Query: 24   SRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSS 83
            S +   S  SS S D D      S +  +  ++ D S     + S  S D+      N S
Sbjct: 803  SSNSSDSSDSSDSSDSDSSN---SSDSSNSSDSSDSSNSSDSSDSSDSSDSSDSDSSNRS 859

Query: 84   SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
             SS  SD +    S        + D S  ++ +  S S D         SS+S DSD   
Sbjct: 860  DSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSD---------SSNSSDSDSSD 910

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
               S +   +    D S     + NS S DS      S          D++     SDS+
Sbjct: 911  SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS----------DSSDSSNSSDSS 960

Query: 204  SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFG 263
            + GD+  SS + + N + SS  S S D  D+S  S++      S +S S+  DS      
Sbjct: 961  NSGDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS--DSSDSSDS 1018

Query: 264  INEI-GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS 322
             N     N    S S+++      SDSS+S + S             +  +   SGS+ S
Sbjct: 1019 SNSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS---------DSSDSSDSSDSSGSSDS 1069

Query: 323  GDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSD 382
             D+ +SS   D +   DSS  +    SS  S DS     SSD  +   S    +   SSD
Sbjct: 1070 SDSSDSSDSSDSSDSSDSSDSSDSSESSD-SSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1128

Query: 383  PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
               + + S  SD SDS  ++ SSDS        + +    +   +    +  S S + S 
Sbjct: 1129 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1188

Query: 443  IPEATPKYSETNAIIGQDINEHIANSKIPGDCPNAVGKS 481
              +++     +N+    D ++   ++    D  ++  KS
Sbjct: 1189 SSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1227



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 99/401 (24%), Positives = 157/401 (39%), Gaps = 32/401 (7%)

Query: 33   SSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRT 92
            S SS   D      S       ++ D S   + + S  S D+      +SS SS  SD +
Sbjct: 859  SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 918

Query: 93   KPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGA 152
                S        + D S  S  +  S S D+        SS+SGDS            +
Sbjct: 919  DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSN----------S 968

Query: 153  TGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISS 212
            +   +  S +  D+ NS      +  + SS     +   D++   + SDS++  D+  SS
Sbjct: 969  SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1028

Query: 213  KTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIG 268
             + + + +S    SS  S S D  D+S  S++    G S +S S+               
Sbjct: 1029 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSS--------------- 1073

Query: 269  GNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 328
             +    S S+++      SDSS S + S   +         +  +   S S+ S D+ NS
Sbjct: 1074 -DSSDSSDSSDSSDSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1132

Query: 329  SKDFDGNGVGDSSARNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRKRSSDPDEA 386
            S   D +   DSS  +   +SS  S+  DS     SSD  +   S    +   SSD  ++
Sbjct: 1133 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1192

Query: 387  GNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLN 427
             + S  S+ SDS  ++ SSDS S    +S  +   G    N
Sbjct: 1193 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNN 1233



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 99/371 (26%), Positives = 152/371 (40%), Gaps = 30/371 (8%)

Query: 55  ETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSG----DSDRTKPFFSLGLGAPGKAEDKS 110
           E+++ S  R DA     E    G   N S S G    DSD T    +      G   +  
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNG---NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDD 536

Query: 111 GDSQDAGGSKSE----DTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDA 166
            D  D+G  KS+    D+        SS S DSD      S +  ++  D   S +   +
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 167 GNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGS 226
            +S S DS +  + SS     +   D+      S+S+S  D+   S + + N + SS  S
Sbjct: 597 DSSNSSDS-SDSSDSSDSSDSSDSSDSKSDSSKSESDS-SDSDSKSDSSDSNSSDSSDNS 654

Query: 227 VSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG 286
            S D  ++S  S++      S +S S+   S  +         N    S S+++      
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSSSSD-------SSNSSDSSDSSDSSNSSES 707

Query: 287 SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGF 346
           SDSS S +          ++   +  N  DS S+ S D+ +SS   D +   DSS  +  
Sbjct: 708 SDSSDSSDSD------SSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDS 761

Query: 347 ENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSD 406
            NSS  S+ S     SSD  +   S    +   SSD  ++ N S  S+ SDS  ++ SSD
Sbjct: 762 SNSSDSSDSS----DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 407 SGSGGGGKSAD 417
           S S     S++
Sbjct: 818 SDSSNSSDSSN 828



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 106/446 (23%), Positives = 169/446 (37%), Gaps = 19/446 (4%)

Query: 18  DGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
           D   + S     S  SS S D D      S +  S       S     + S  S D+   
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607

Query: 78  GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
              + SS S DS  +K   S        ++ KS DS D+  S S D         SS+S 
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS-DSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 138 DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGF 197
           DS            +       S    D+ +S    + +  + SS     +   D++   
Sbjct: 667 DSSDSSDSSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD----SSDSDSSDSS 722

Query: 198 EVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
           + S+SNS  D+  S+ +   + + SS  S S D  D+S  S +        +  S+  DS
Sbjct: 723 DSSNSNS-SDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNS--------SDSSDSSDS 773

Query: 258 GQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAE-FNFRD 316
                  N    N  S S  +++      SDSS+S + S   +    ++   ++  N  D
Sbjct: 774 SDSSDSSNSSDSNDSSNS--SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831

Query: 317 SGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
           S  + +  + + S D   +   DSS R+   NSS  S DS     SSD  +   S     
Sbjct: 832 SSDSSNSSDSSDSSDSSDSSDSDSSNRSDSSNSSD-SSDSSDSSNSSDSSDSSDSSDSNE 890

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
              SSD  ++ N S  SD SDS  ++ SSDS +      +      ++  +    +  S 
Sbjct: 891 SSNSSDSSDSSN-SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 949

Query: 437 SEKGSHIPEATPKYSETNAIIGQDIN 462
           S   S+  +++     +N+    D N
Sbjct: 950 SSDSSNSSDSSNSGDSSNSSDSSDSN 975



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 96/402 (23%), Positives = 160/402 (39%), Gaps = 18/402 (4%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNS 82
            +S S   S  S+SS   D      S E  +  ++ D S       S  S  + +    NS
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 923

Query: 83   SSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKK 142
            S SS  S+ +    S        + D S  S  +  S S D+        S+SS  SD  
Sbjct: 924  SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSGDSSNSSDSSDSNSSDSSDSS 983

Query: 143  KPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDS 202
                S +   + +  D S    D+ NS      +  + SS     +   D++   + SDS
Sbjct: 984  NSSDSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSDSSDSSDS 1039

Query: 203  NSFGDTGISSKTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSG 258
            +   D+  SS + + + +S    SSG S S D  D+S  S++      S +S S+     
Sbjct: 1040 SDSSDSSNSSDSSDSSDSSDSSDSSGSSDSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1099

Query: 259  QEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSG 318
             +    ++   +    S S+++      SDSS+S + S   +         +  +   S 
Sbjct: 1100 SDSSDSSD-SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1158

Query: 319  SNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI--SEDSGVILGSSDQHEVELSRTGGN 376
            S+ S D+ +SS   D +   DSS  N   +SS    S DS     SSD  +   S +  N
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN 1218

Query: 377  RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADE 418
                   DE+ + S   + +++G ++ S   GS     ++D+
Sbjct: 1219 -------DESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1253



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 91/387 (23%), Positives = 150/387 (38%), Gaps = 20/387 (5%)

Query: 99  GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
           G G   +  +K G S + G   + D      F   S  GD        +    A  E ++
Sbjct: 425 GPGQKSEPGNKVGHS-NTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN 483

Query: 159 KSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVE 216
            S  R DA  + S++S   G GS          D+      SDSN  G+ G   + K+  
Sbjct: 484 NSSSRGDASYN-SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G   S S  S S D  ++S  S++        NS S+   S  +    ++   +    S 
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSD--SDSSDSSN 600

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
           S+++      SDSS S + S        ++K  +  +  DS  + S  + + S   D + 
Sbjct: 601 SSDSSDSSDSSDSSDSSDSS--------DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652

Query: 337 VGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVS 396
             DSS  +   NSS  S+ S     SSD      S +  +   SSD  ++ + S  S+ S
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSD----SSDSSSSSDSSSSSDSSNSSDSSDSSDSSNSSESS 708

Query: 397 DS--GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETN 454
           DS    ++ SSDS       S+D     +S  ++  ++  S +   S     +   S+++
Sbjct: 709 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 455 AIIGQDINEHIANSKIPGDCPNAVGKS 481
                  +   +NS    D  N+   S
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSS 795



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 107/472 (22%), Positives = 172/472 (36%), Gaps = 67/472 (14%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQD----AGSPKSEDT 74
           G+++   + G +  S+++G+ D+     + + G  G  ED +  ++D    AGS  S D 
Sbjct: 138 GQVSIIDNAGATNRSNTNGNTDKNTQ--NGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDN 195

Query: 75  PAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSS 134
                 NS  + G++    P  +       +AE   G  +DAG   S+ +P G       
Sbjct: 196 EDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDE 255

Query: 135 SSGDSDKKKPLFSFEFGATGED---EDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKG 191
             G  D +      E    G+D     K +E  D G     DS ++G  S   +    +G
Sbjct: 256 DEGSGDDED-----EEAGNGKDSSNNSKGQEGQDHGKEDDHDS-SIGQNSDSKEYYDPEG 309

Query: 192 DAAFGFEV-------SDSNSFG---DTGI------------SSKTVEGNQT--------- 220
                 EV       S+ NS G   D G              SK VE   T         
Sbjct: 310 KEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVG 369

Query: 221 SSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE-----------IGG 269
            S    + I    +  R+  + VG G+        D GQ G  + +           I G
Sbjct: 370 KSQDKGIEIKGPSSGNRNITKEVGKGN----EGKEDKGQHGMILGKGNVKTQGEVVNIEG 425

Query: 270 NGMSGSVSAEAGFKGFGSDSSSSVEKSWLFE---FGLGETKGGAEFNFRDSGSNQSGDNG 326
            G       + G    GSDS+S    S+ F+       +     E N  D  +++S +N 
Sbjct: 426 PGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNS 485

Query: 327 NSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEA 386
           +S  D   N        NG ++     +DS     +SD +  + +  G N    +D  ++
Sbjct: 486 SSRGDASYNSDESKDNGNGSDSKGAEDDDSD---STSDTNNSDSNGNGNNGNDDNDKSDS 542

Query: 387 GNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSE 438
           G     S  SDS  ++ SSDS       S+D      S  ++   +  S S+
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 94/382 (24%), Positives = 142/382 (37%), Gaps = 44/382 (11%)

Query: 51  GSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS 110
           G       K ++ QD G     D+  G   +S        +  P   +      K+E+ S
Sbjct: 270 GKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENS 329

Query: 111 -GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            G  +D G  + EDT                K+      E  A G+ +DK  E     + 
Sbjct: 330 AGIPEDNGSQRIEDTQKLNHRESKRVENRITKES-----ETHAVGKSQDKGIEIKGPSSG 384

Query: 170 RSEDSPAVGTGSSGLK------LGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS 223
               +  VG G+ G +      +  GKG+     EV +       G   K+  GN+   S
Sbjct: 385 NRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIE-----GPGQKSEPGNKVGHS 439

Query: 224 G-GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF 282
             GS S   G  S+  +++ + G   NS         E  G ++   N  S + S+  G 
Sbjct: 440 NTGSDSNSDGYDSYDFDDKSMQGDDPNS-------SDESNGNDD--ANSESDNNSSSRGD 490

Query: 283 KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS-------GSNQSGDNGNSSKDFDGN 335
             + SD S         + G G    GAE +  DS        SN +G+NGN   D   +
Sbjct: 491 ASYNSDESK--------DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542

Query: 336 GVGDSSARNGFENSSGISEDSGVILGS--SDQHEVELSRTGGNRKRSSDPDEAGNLSPGS 393
           G G S + +   + S  S DS     S  SD +    S +  +    S   ++ + S  S
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602

Query: 394 DVSDSGGNTWSSDSGSGGGGKS 415
           D SDS  ++ SSDS      KS
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKS 624



>gi|51105835|gb|EAL24435.1|   FLJ45737 protein [Homo sapiens]
          Length = 237

 Score =  106 bits (264), Expect = 3e-22
 Identities = 64/209 (30%), Positives = 94/209 (44%), Gaps = 15/209 (7%)

Query: 644 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNP---SSCIS-IE 696
           T   GLCG++    +DDF++    +E +  AFA+ +++     CP  +    S C +  +
Sbjct: 26  TQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQ 85

Query: 697 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 756
           +  FAE  C IL   S     CH +V+ +P++  C    C C+   DCLC +L  Y + C
Sbjct: 86  RHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRC 143

Query: 757 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 815
           A+ E     WR   LC   CP G  ++    AC   C     +   C      V GC CP
Sbjct: 144 AQ-EGASPPWRNQTLCPVMCPGGQEYRECAPACGQHC----GKPEDCGELGSCVAGCNCP 198

Query: 816 DAMYQNNEGNCVLKSQCDCYINDEVMQPG 844
             +  + EG CV  S C C +      PG
Sbjct: 199 LGLLWDPEGQCVPPSLCPCQLGARRYAPG 227



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 50/162 (30%), Positives = 72/162 (44%), Gaps = 12/162 (7%)

Query: 972  KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE--C-SDTVAQTFPCDSNPYC 1028
            +V GLCG    + +DDF T    V +    F + ++ + +  C S+  A   PC ++   
Sbjct: 27   QVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQR 86

Query: 1029 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1088
             A+A   C IL  S F++CH  VD   ++  C+   C CD     L  C  ++ YA  C+
Sbjct: 87   HAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCL--CPVLSAYARRCA 144

Query: 1089 AVGVCVSWRKPNLCPVYC----DYYNAPGECRWHY---EPCG 1123
              G    WR   LCPV C    +Y      C  H    E CG
Sbjct: 145  QEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCG 186



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 33/138 (23%), Positives = 52/138 (37%), Gaps = 15/138 (10%)

Query: 472 GDCPNAVGKSYEVCEDGIQH-------CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQT 524
           G CP+        C    Q        C  +  + F++C ++      Y + C+   C  
Sbjct: 67  GRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFY-LRCLAAVCGC 125

Query: 525 RDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 583
              +   C   S  +R CA +G      WR+ +  +C    CP    Y+EC P+    C 
Sbjct: 126 DPGSDCLCPVLSAYARRCAQEGASP--PWRNQT--LCPVM-CPGGQEYRECAPACGQHCG 180

Query: 584 NVAPFQD-SECVSGCTCP 600
                 +   CV+GC CP
Sbjct: 181 KPEDCGELGSCVAGCNCP 198



>gi|51493056|ref|XP_495859.1|   PREDICTED: similar to mucin 5 [Homo sapiens]
          Length = 657

 Score =  101 bits (252), Expect = 8e-21
 Identities = 117/454 (25%), Positives = 163/454 (35%), Gaps = 63/454 (13%)

Query: 606  IFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
            +   SSSY +VE    + L         L + +       T GLCG +N       + S 
Sbjct: 169  LIQQSSSYTKVEARLGLVLMWNHDD--SLLLELDTKYANKTCGLCGDFNGMPVVSELLSH 226

Query: 666  NILEKTSQAFANSWEM----------MSCPKGNPSSCISIEKEKFAERHCGILLDSSGPL 715
            N  + T   F N  +M          +  P  N S+   I         C  LL      
Sbjct: 227  NT-KLTPMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGI---------CEELLHGQ-LF 275

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQ--DCLCTILGNYVKACAEKETYIVGWR-TGLCE 772
            + C  +V+   Y E C++  C CE++    C+C  L  Y + C         WR    C 
Sbjct: 276  SGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCP 335

Query: 773  HSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGN--CVLKS 830
              CP+ + +      C  +C S  E  R+C  ED  V GC CP+    ++ G   CV  S
Sbjct: 336  QKCPNNMQYHECRSPCADTC-SNQEHSRAC--EDHCVAGCFCPEGTVLDDIGQTGCVPVS 392

Query: 831  QCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ-IPIDLTLQNCSG-------GAEYV- 881
            +C C  N     PG     D   C C  G   CQ +P   T     G       G +Y  
Sbjct: 393  KCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPGTCSVLGGAHFSTFDGKQYTV 452

Query: 882  --DCS----DPKAQRRTNRTCSTRNIPVFDDQNIVLQ-----DGKVTAVKSTESKKCELN 930
              DCS     P            R   + D +  +       DG  T V    S +  LN
Sbjct: 453  HGDCSYVLTKPCDSSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLN 512

Query: 931  ----------ANAYSIHTVGLYLILKFQNGIIVIWD--KNTRLSVILDPNWNGKVCGLCG 978
                      AN         ++I +   G+ +        +L + L P   G+ CGLCG
Sbjct: 513  QIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCG 572

Query: 979  NNNGDLKDDFTTRYSSVASGALEFGNSWKTSQEC 1012
            N N    DDF T    V + A  F N++KT   C
Sbjct: 573  NFNSIQADDFRTLSGVVEATAAAFFNTFKTQAAC 606



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 65/264 (24%), Positives = 113/264 (42%), Gaps = 24/264 (9%)

Query: 877  GAEYVDCSDPKAQRRTNRTCSTRNIPVFDDQNIVLQDGKVTAVKSTESKKCELNANAYSI 936
            GA Y D +  + +R       T +  +     +V+Q  K + + +        + +   I
Sbjct: 112  GAAYEDFNI-QLRRSQESAAPTLSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLI 170

Query: 937  HTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNG-DLKDDFTTRYSSV 995
                 Y  ++ + G++++W+ +  L + LD  +  K CGLCG+ NG  +  +  +  + +
Sbjct: 171  QQSSSYTKVEARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL 230

Query: 996  ASGALEFGNSWK---TSQECSDTVAQTFPCDSNPY--CKAWAVRKCEILRDSTFRDCHNK 1050
                +EFGN  K    +++C D V +     S  +  C+       E+L    F  C   
Sbjct: 231  T--PMEFGNLQKMDDPTEQCQDPVPEPPRNCSTGFGICE-------ELLHGQLFSGCVAL 281

Query: 1051 VDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS-AVGVCVSWRKPNLCPVYCDYY 1109
            VD  +Y + C ++ C C+        C  +A Y+  C+ A G+   WR P+ CP  C   
Sbjct: 282  VDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNN 341

Query: 1110 NAPGECRWHYEPCGTVTAKTCKDQ 1133
                ECR    PC    A TC +Q
Sbjct: 342  MQYHECR---SPC----ADTCSNQ 358



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 28/83 (33%), Positives = 51/83 (61%), Gaps = 1/83 (1%)

Query: 604 IQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMS 663
           + IF  S+ ++  +T   ++L +Q+VP MQL++ + P     T GLCG++N+   DDF +
Sbjct: 525 VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRT 584

Query: 664 SQNILEKTSQAFANSWE-MMSCP 685
              ++E T+ AF N+++   +CP
Sbjct: 585 LSGVVEATAAAFFNTFKTQAACP 607



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 40/137 (29%), Positives = 57/137 (41%), Gaps = 11/137 (8%)

Query: 474 CPNAVGKSYEVCEDGIQHCNKII-GTYFEKCGKVAALSNDYKMICIDEYCQTRDK---TS 529
           C + V +    C  G   C +++ G  F  C  +  + + Y   C  + C   D    + 
Sbjct: 248 CQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGS-YLEACRQDLCFCEDTDLLSC 306

Query: 530 TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQ 589
            C T +E SR C   G G  + WR      C  Q+CP    Y EC      TCSN    +
Sbjct: 307 VCHTLAEYSRQCTHAG-GLPQDWRGPD--FC-PQKCPNNMQYHECRSPCADTCSNQEHSR 362

Query: 590 --DSECVSGCTCPEDKI 604
             +  CV+GC CPE  +
Sbjct: 363 ACEDHCVAGCFCPEGTV 379



>gi|38173826|gb|AAH60868.1|   BMPER protein [Homo sapiens]
 gi|57013325|sp|Q8N8U9|BMER_HUMAN   BMP-binding endothelial regulator protein precursor (Bone
            morphogenetic protein-binding endothelial cell
            precursor-derived regulator) (Crossveinless-2 protein)
            (hCV2)
          Length = 685

 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 80/344 (23%), Positives = 136/344 (39%), Gaps = 44/344 (12%)

Query: 812  CTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQI------ 865
            C C     +     C+  S C           GK+++      +C +   +C +      
Sbjct: 322  CACVKGRTECRNKQCIPISSCP---------QGKILNRKGCCPICTEKPGVCTVFGDPHY 372

Query: 866  -PIDLTLQNCSGGAEYV---DCSDPKAQ---------RRTNRTCSTRNIPVFDDQNIVLQ 912
               D    N  G  +YV   DCS P +          RRT     T+++ +   ++ V  
Sbjct: 373  NTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432

Query: 913  DGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
               +T   +         A  + I   G  L +  + G+ + WD ++ + V+  P+  GK
Sbjct: 433  QQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK--TSQECSDTVAQTFP--CDSNPYC 1028
            +CGLCGN NG  +DD      +      +F  SW+  +++ C+    +  P  C      
Sbjct: 493  LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKV 552

Query: 1029 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1088
            K  A R+C+ L+   F+ CH+ VD + ++  C+ + C C +      +C +   Y  AC 
Sbjct: 553  KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC--YCESFLAYTRACQ 610

Query: 1089 AVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTC 1130
              G+ V W     C        A  +C+    Y+ CG    KTC
Sbjct: 611  REGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTC 646



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 60/240 (25%), Positives = 92/240 (38%), Gaps = 36/240 (15%)

Query: 619 YFHVKLQ---IQIVPVMQLYVSMPPNQFTDTV----------GLCGSYNNKAEDDFMSSQ 665
           +FH+ L    +++     L +S   + F + +          GLCG+YN    DD +   
Sbjct: 453 HFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGD 512

Query: 666 NILEKTSQAFANSWEMMS---C----PKGNPSSCISIEKEKF-AERHCGILLDSSGPLAS 717
              +     FA SW + S   C     K  P  C    K K  A R C  L   S    +
Sbjct: 513 GNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQT 570

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGW--RTGLCEHSC 775
           CH  V+   ++  C    C C   ++C C     Y +AC ++E   V W  +       C
Sbjct: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRAC-QREGIKVHWEPQQNCAATQC 629

Query: 776 PSGLVFKYNVKACNSSCRSLSE---RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 832
             G V+      C  +C + +E    ++ C      V GC CP A    ++G C+    C
Sbjct: 630 KHGAVYDTCGPGCIKTCDNWNEIGPCNKPC------VAGCHCP-ANLVLHKGRCIKPVLC 682



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 490 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGT 548
           + C K+    F+ C      +  Y+  C+ + C+    K   C+++   +R C  +G   
Sbjct: 558 RECQKLKSWEFQTCHSTVDYATFYRS-CVTDMCECPVHKNCYCESFLAYTRACQREGIKV 616

Query: 549 FESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN---VAPFQDSECVSGCTCPEDKI 604
              W    +  C   +C    +Y  CGP    TC N   + P  +  CV+GC CP + +
Sbjct: 617 H--WEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLV 670



>gi|51105884|gb|EAL24468.1|   BMP-binding endothelial regulator precursor protein [Homo sapiens]
 gi|21755569|dbj|BAC04712.1|   unnamed protein product [Homo sapiens]
 gi|37693519|ref|NP_597725.1|   BMP-binding endothelial regulator precursor protein [Homo sapiens]
 gi|32892146|gb|AAP89012.1|   crossveinless-2 [Homo sapiens]
          Length = 685

 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 80/344 (23%), Positives = 136/344 (39%), Gaps = 44/344 (12%)

Query: 812  CTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQI------ 865
            C C     +     C+  S C           GK+++      +C +   +C +      
Sbjct: 322  CACVKGRTECRNKQCIPISSCP---------QGKILNRKGCCPICTEKPGVCTVFGDPHY 372

Query: 866  -PIDLTLQNCSGGAEYV---DCSDPKAQ---------RRTNRTCSTRNIPVFDDQNIVLQ 912
               D    N  G  +YV   DCS P +          RRT     T+++ +   ++ V  
Sbjct: 373  NTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432

Query: 913  DGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
               +T   +         A  + I   G  L +  + G+ + WD ++ + V+  P+  GK
Sbjct: 433  QQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK--TSQECSDTVAQTFP--CDSNPYC 1028
            +CGLCGN NG  +DD      +      +F  SW+  +++ C+    +  P  C      
Sbjct: 493  LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKV 552

Query: 1029 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1088
            K  A R+C+ L+   F+ CH+ VD + ++  C+ + C C +      +C +   Y  AC 
Sbjct: 553  KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC--YCESFLAYTRACQ 610

Query: 1089 AVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTC 1130
              G+ V W     C        A  +C+    Y+ CG    KTC
Sbjct: 611  REGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTC 646



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 60/240 (25%), Positives = 92/240 (38%), Gaps = 36/240 (15%)

Query: 619 YFHVKLQ---IQIVPVMQLYVSMPPNQFTDTV----------GLCGSYNNKAEDDFMSSQ 665
           +FH+ L    +++     L +S   + F + +          GLCG+YN    DD +   
Sbjct: 453 HFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGD 512

Query: 666 NILEKTSQAFANSWEMMS---C----PKGNPSSCISIEKEKF-AERHCGILLDSSGPLAS 717
              +     FA SW + S   C     K  P  C    K K  A R C  L   S    +
Sbjct: 513 GNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQT 570

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGW--RTGLCEHSC 775
           CH  V+   ++  C    C C   ++C C     Y +AC ++E   V W  +       C
Sbjct: 571 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRAC-QREGIKVHWEPQQNCAATQC 629

Query: 776 PSGLVFKYNVKACNSSCRSLSE---RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 832
             G V+      C  +C + +E    ++ C      V GC CP A    ++G C+    C
Sbjct: 630 KHGAVYDTCGPGCIKTCDNWNEIGPCNKPC------VAGCHCP-ANLVLHKGRCIKPVLC 682



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 490 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGT 548
           + C K+    F+ C      +  Y+  C+ + C+    K   C+++   +R C  +G   
Sbjct: 558 RECQKLKSWEFQTCHSTVDYATFYRS-CVTDMCECPVHKNCYCESFLAYTRACQREGIKV 616

Query: 549 FESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN---VAPFQDSECVSGCTCPEDKI 604
              W    +  C   +C    +Y  CGP    TC N   + P  +  CV+GC CP + +
Sbjct: 617 H--WEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLV 670



>gi|18916818|dbj|BAB85551.1|   KIAA1965 protein [Homo sapiens]
          Length = 565

 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 80/344 (23%), Positives = 136/344 (39%), Gaps = 44/344 (12%)

Query: 812  CTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQI------ 865
            C C     +     C+  S C           GK+++      +C +   +C +      
Sbjct: 202  CACVKGRTECRNKQCIPISSCP---------QGKILNRKGCCPICTEKPGVCTVFGDPHY 252

Query: 866  -PIDLTLQNCSGGAEYV---DCSDPKAQ---------RRTNRTCSTRNIPVFDDQNIVLQ 912
               D    N  G  +YV   DCS P +          RRT     T+++ +   ++ V  
Sbjct: 253  NTFDGRTFNFQGTCQYVLTKDCSSPASPFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 312

Query: 913  DGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGK 972
               +T   +         A  + I   G  L +  + G+ + WD ++ + V+  P+  GK
Sbjct: 313  QQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 372

Query: 973  VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK--TSQECSDTVAQTFP--CDSNPYC 1028
            +CGLCGN NG  +DD      +      +F  SW+  +++ C+    +  P  C      
Sbjct: 373  LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKV 432

Query: 1029 KAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACS 1088
            K  A R+C+ L+   F+ CH+ VD + ++  C+ + C C +      +C +   Y  AC 
Sbjct: 433  KLRAHRECQKLKSWEFQTCHSTVDYATFYRSCVTDMCECPVHKNC--YCESFLAYTRACQ 490

Query: 1089 AVGVCVSWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTC 1130
              G+ V W     C        A  +C+    Y+ CG    KTC
Sbjct: 491  REGIKVHWEPQQNC--------AATQCKHGAVYDTCGPGCIKTC 526



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 60/240 (25%), Positives = 92/240 (38%), Gaps = 36/240 (15%)

Query: 619 YFHVKLQ---IQIVPVMQLYVSMPPNQFTDTV----------GLCGSYNNKAEDDFMSSQ 665
           +FH+ L    +++     L +S   + F + +          GLCG+YN    DD +   
Sbjct: 333 HFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGD 392

Query: 666 NILEKTSQAFANSWEMMS---C----PKGNPSSCISIEKEKF-AERHCGILLDSSGPLAS 717
              +     FA SW + S   C     K  P  C    K K  A R C  L   S    +
Sbjct: 393 GNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQGTVKVKLRAHRECQKL--KSWEFQT 450

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGW--RTGLCEHSC 775
           CH  V+   ++  C    C C   ++C C     Y +AC ++E   V W  +       C
Sbjct: 451 CHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRAC-QREGIKVHWEPQQNCAATQC 509

Query: 776 PSGLVFKYNVKACNSSCRSLSE---RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 832
             G V+      C  +C + +E    ++ C      V GC CP A    ++G C+    C
Sbjct: 510 KHGAVYDTCGPGCIKTCDNWNEIGPCNKPC------VAGCHCP-ANLVLHKGRCIKPVLC 562



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 29/119 (24%), Positives = 50/119 (42%), Gaps = 10/119 (8%)

Query: 490 QHCNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTR-DKTSTCDTYSELSRLCASDGPGT 548
           + C K+    F+ C      +  Y+  C+ + C+    K   C+++   +R C  +G   
Sbjct: 438 RECQKLKSWEFQTCHSTVDYATFYRS-CVTDMCECPVHKNCYCESFLAYTRACQREGIKV 496

Query: 549 FESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSN---VAPFQDSECVSGCTCPEDKI 604
              W    +  C   +C    +Y  CGP    TC N   + P  +  CV+GC CP + +
Sbjct: 497 H--WEPQQN--CAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC-NKPCVAGCHCPANLV 550



>gi|13383506|gb|AAK21011.1|   zonadhesin [Homo sapiens]
          Length = 915

 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 55/205 (26%), Positives = 89/205 (43%), Gaps = 31/205 (15%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
           +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 645 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 704

Query: 690 ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                             S C   +    + + C +L D  GP A+CH  V P+P+ E C
Sbjct: 705 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHC 764

Query: 732 KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
               C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 765 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 824

Query: 788 CNSSCRSLSERDRSCDVEDVPVDGC 812
           C +SC +L++     D E   V+GC
Sbjct: 825 CPASCANLADPG---DCEGPCVEGC 846



 Score = 89.0 bits (219), Expect = 5e-17
 Identities = 102/417 (24%), Positives = 160/417 (38%), Gaps = 84/417 (20%)

Query: 775  CPSGLVFKYNVKACNSSCRSLSE-RD--------RSCDVED---------VPVD--GCTC 814
            CP G  +      C  +C S++  RD         SC+ +          VP+   GCT 
Sbjct: 3    CPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 62

Query: 815  PDAMYQN------NEGNCVLKSQCDCYINDEVMQ----PGKLIHIDDNKCVCR-DGILLC 863
            P   Y         E  C     C  + N    Q    P ++    D    CR  G+ +C
Sbjct: 63   PAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGLLHCRASGVGVC 122

Query: 864  QIPIDLTLQNCSGGAEYVD--CS------------------DPKAQRRTNRTCSTRNIPV 903
            Q+P +    +  G    +   C+                    K ++    T + R   V
Sbjct: 123  QLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPLFKISAKHEKEEGGTEAFRLHEV 182

Query: 904  FDDQNIVLQDGKVTAVKS----TESKKCELNANAY----SIHTVGLYLILKFQNGIIVIW 955
            + D    + D +VT  K       SK+  L A +     S+ +  +Y I+  + G+ V +
Sbjct: 183  YID----IYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYTIVNIKIGVQVKF 238

Query: 956  DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1015
            D N  L + +   + GKVCG+CGN N + +D+       VA+   EF NSWK      D 
Sbjct: 239  DGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKD--IDP 296

Query: 1016 VAQTFPCD---------SNP--YCKAWAVR----KCE-ILRDSTFRDCHNKVDPSAYHDV 1059
              Q+ P D          NP   C+A  +R    KCE  LR   +  C +++D + +   
Sbjct: 297  SCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVD 356

Query: 1060 CIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGEC 1115
            C      C+  G Y   C A+  +   C + G+    WR  + CP+ C  Y++   C
Sbjct: 357  CAN--TLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNC 411



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 65/282 (23%), Positives = 104/282 (36%), Gaps = 25/282 (8%)

Query: 605 QIFNASSSYLQVETYFHVKLQIQIV--PVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 662
           QI   S     + T  ++K+ +Q+       L + +P   +    G+CG++N++ ED+ M
Sbjct: 213 QIPGVSVKSSSIYTIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELM 272

Query: 663 SSQNILEKTSQAFANSWE-------MMSCP----------KGNPSSCISIEKEKFAERHC 705
              + +  +   F NSW+         S P          + NPS        + A   C
Sbjct: 273 MPSDEVANSDSEFVNSWKDKDIDPSCQSLPVDEQQIPAEQQENPSGNCRAADLRRAREKC 332

Query: 706 GILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVG 765
              L  +   A C   ++  P+  +C    C        LC  L  +   C  +      
Sbjct: 333 EAAL-RAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPL 391

Query: 766 WR-TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG 824
           WR +  C   CP+   +   + +C+ SC  L  R     V     +GC C    Y  +E 
Sbjct: 392 WRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPG-YVLSED 450

Query: 825 NCVLKSQCDCYINDEVMQPGKLIHIDD---NKCVCRDGILLC 863
            CV +SQC C        P     +      KCVC  G + C
Sbjct: 451 KCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGAIQC 492



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 47/191 (24%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 625  LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 682

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 683  TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 741

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D    F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 742  ADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 801

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 802  WRDRTLCAMEC 812



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 11/104 (10%)

Query: 500 FEKCGKVAALSNDYKMICIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSD 555
           F  C +  A    ++  C+ + C  +D        C   S  + LC   G      WR  
Sbjct: 748 FAACHQTVA-PEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDR 805

Query: 556 SDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE--CVSGC 597
           +  +C  + CP   IY+ C    PA+C+N+A   D E  CV GC
Sbjct: 806 T--LCAME-CPAGTIYQSCMTPCPASCANLADPGDCEGPCVEGC 846



>gi|1932794|gb|AAC51208.1|   zonadhesin [Homo sapiens]
          Length = 363

 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 55/208 (26%), Positives = 89/208 (42%), Gaps = 31/208 (14%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE------MMSCPKGNP 689
           +S+P        GLCG+Y+   ++D M     L +    F NSWE      ++  P+  P
Sbjct: 80  ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 139

Query: 690 ------------------SSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEEC 731
                             S C   +    + + C +L D   P A+CH  V P+P+ E C
Sbjct: 140 AEEEGQGAELGLRTGLQVSECSPEQLASNSTQACRVLADPQAPFAACHQTVPPEPFQEHC 199

Query: 732 KKYTCTCEN---SQDCLCTILGNYVKACAEKETYIVGWR-TGLCEHSCPSGLVFKYNVKA 787
               C+ ++    ++  C +L  Y   C E    + GWR   LC   CP+G +++  +  
Sbjct: 200 VLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTP 259

Query: 788 CNSSCRSLSERDRSCDVEDVPVDGCTCP 815
           C +SC +L++     D E   V+GC  P
Sbjct: 260 CPASCANLADPG---DCEGPCVEGCADP 284



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 28/191 (14%)

Query: 941  LYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGAL 1000
            LYL+  F+  ++V +       + L   + G V GLCGN + + K+D      ++     
Sbjct: 60   LYLVTDFE--LVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLN 117

Query: 1001 EFGNSWKTSQECS---------------------DTVAQTFPCDSNPYCKAWAVRKCEIL 1039
             FGNSW+   E +                      T  Q   C S     + + + C +L
Sbjct: 118  TFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSEC-SPEQLASNSTQACRVL 176

Query: 1040 RD--STFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1095
             D  + F  CH  V P  + + C+ + C A D   +    C  ++ YA  C   G  ++ 
Sbjct: 177  ADPQAPFAACHQTVPPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAG 236

Query: 1096 WRKPNLCPVYC 1106
            WR   LC + C
Sbjct: 237  WRDRTLCAMEC 247



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 10/90 (11%)

Query: 517 CIDEYCQTRDKTST----CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYK 572
           C+ + C  +D        C   S  + LC   G      WR  +  +C  + CP   IY+
Sbjct: 199 CVLDLCSAQDPREQEELRCQVLSGYAILCQEAG-AALAGWRDRT--LCAME-CPAGTIYQ 254

Query: 573 ECGPSNPATCSNVAPFQDSE--CVSGCTCP 600
            C    PA+C+N+A   D E  CV GC  P
Sbjct: 255 SCMTPCPASCANLADPGDCEGPCVEGCADP 284



>gi|28557150|dbj|BAC57496.1|   hornerin [Homo sapiens]
          Length = 493

 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 133/509 (26%), Positives = 189/509 (37%), Gaps = 78/509 (15%)

Query: 17  KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
           + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 16  RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 75

Query: 73  D-TPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFY 131
             +P G      S SG S    P+           E  SG S   G  +S      G+  
Sbjct: 76  SYSPYG------SGSGWSSSRGPY-----------ESGSGHSSGLGHRESRSGQSSGYGQ 118

Query: 132 GSSSSGDSDK--KKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
             SSSG S    +    S +  + G+    S +    G   S  S + G G  G   G  
Sbjct: 119 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 178

Query: 190 KGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLN 249
            G +  G     S S+G  G       G+  SSS G     LG++S    ++   G S +
Sbjct: 179 PGHSQRGSGSRQSPSYGRHG------SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS 232

Query: 250 SISNLWDSGQEGFGINEIGGNGMSGSVSAEAG-FKGFGSDSSSSVEKSWLFEFGLGETKG 308
                    Q G G     G G  GS S ++   +  GS S SS   S   + G G  + 
Sbjct: 233 -------YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS---SHYGQHGSGSRQS 282

Query: 309 GAEFNFRDSGSNQSGDNG--------NSSKDFDGNGVGDSSARNGFENSSGISEDSGVIL 360
                 + SGS QS   G        +SS    G+G G SS+R  +E+ SG S   G   
Sbjct: 283 SGH-GRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFG--- 338

Query: 361 GSSDQHEVELSRTGGNRKRSSDPDEAGNL-SPGSDVSDSG-GNTWSSDSGSGGGGKSADE 418
               QHE   S +G +   S     +G+  S G   S SG  +T+  +  S G   S   
Sbjct: 339 ----QHE---SGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGH 391

Query: 419 LGVGASGLNEFGETGLSGSEKGSHIPEA-----TPKYSETNAIIGQD--INEHIANSKIP 471
            G G+S  + +G  G    +  SH         +  Y +  +  GQ    ++H + S   
Sbjct: 392 RGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQD 451

Query: 472 GDCPNAVGKSYEVCEDGIQHCNKIIGTYF 500
           G         Y  C+ G  H     G+YF
Sbjct: 452 G---------YSYCKGGSNHDGGSSGSYF 471



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 84/330 (25%), Positives = 122/330 (36%), Gaps = 17/330 (5%)

Query: 116 AGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSP 175
           +G   S      G   G SS G+        S  +G  G    +S      G S S  SP
Sbjct: 2   SGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHG-SGSGQSP 60

Query: 176 AVGTGSSGLKLGAGKGDAAFGFEVSDSNSFG--DTGISSKTVEGNQTSSSGGSVSIDLGD 233
           +   G  G   G     + +G     S+S G  ++G    +  G++ S SG S       
Sbjct: 61  SPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHG 120

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSV 293
           +S    +     GS +  S+    GQ G    +   +G  GS S+++   G+G   S S 
Sbjct: 121 SSSGHSSTHGQHGSTSGQSS--SCGQHGASSGQSSSHGQHGSGSSQSS--GYGRQGSGSG 176

Query: 294 EKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGIS 353
           +     + G G  +  +       G + SG   +SS    G+G+G+SS     E+SSG S
Sbjct: 177 QSPGHSQRGSGSRQSPSY------GRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 230

Query: 354 EDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSG 410
             S    GS   H     + G    +SS  +  G+ S  S       SG    S     G
Sbjct: 231 -SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG 289

Query: 411 GGGKSADELGVGASGLNEFGETGLSGSEKG 440
            G   +   G   SGL      G  GS  G
Sbjct: 290 SGSGQSPSRGRHGSGLGHSSSHGQHGSGSG 319



>gi|55665870|emb|CAH70026.1|   novel S-100\/ICaBP type calcium binding domain, EF hand domain and
           Filaggrin domain containing protein [Homo sapiens]
 gi|57864582|ref|NP_001009931.1|   hornerin [Homo sapiens]
 gi|45476906|sp|Q86YZ3|HORN_HUMAN   Hornerin
          Length = 2850

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 121/471 (25%), Positives = 174/471 (36%), Gaps = 71/471 (15%)

Query: 17  KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
           + G+ +     G S GSSSS    G   R+    S      G++   SR R ++GS +S 
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556

Query: 73  DTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPG--GFF 130
                G+ +  SSS     +    S GLG       +S      G S    +  G  G  
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616

Query: 131 YGSSSS-----------------GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
            G SSS                 G    +   +  +   +G+   + R   D G+S S  
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYG 676

Query: 174 SPAVGTG--SSGLKLGAGKGDAA-FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
               G+G  SS    G+  G ++ FG +     S G +   S       + SSG      
Sbjct: 677 QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS-----GSSHSSGYRKHGS 731

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA---------- 280
               S RSE      GS + +S+ +  GQ G G ++  G+G  GS S  +          
Sbjct: 732 RSGQSSRSEQH----GSSSGLSSSY--GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785

Query: 281 ------GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-GDNGNSSKDFD 333
                 G  G G+  SSS      +E G G+  G   F   +SGS Q    +G++S  F 
Sbjct: 786 GHSSSHGQHGSGTSCSSSCGH---YESGSGQASG---FGQHESGSGQGYSQHGSASGHFS 839

Query: 334 GNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEA---GNLS 390
             G   S+  +G  +SSG  + S     S  QHE       G  +  S   ++   G   
Sbjct: 840 SQGRHGST--SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897

Query: 391 PGSDVSDSGGNTWSSDSGSGGG-GKSADELGVGASGLNEFGETGLSGSEKG 440
            GS  S S G       GSG G   S+   G G+   + FG    SG   G
Sbjct: 898 SGSGQSPSYGR-----HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 120/444 (27%), Positives = 155/444 (34%), Gaps = 48/444 (10%)

Query: 25   RSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSS 84
            R G  S  SSSSG  D      S +  S G+ E  S      G   S    + G     S
Sbjct: 843  RHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898

Query: 85   SSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGFFYGSSSSGDSDKKK 143
             SG S       S    +       SG  Q +G G KS      G+    S SG S   +
Sbjct: 899  GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                 + G+      +S +      S S  S + G   SG +   G G    G   S S 
Sbjct: 959  -----QHGSRSGQSSRSEQH----GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009

Query: 204  SFGDTGISS---------KTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNS 250
            S G  G  S         ++  G  +S     SG   S  LG    RS      G   +S
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 1069

Query: 251  ISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETK 307
              +    GQ G    +    G +G S   S+  G  G GS  SS   +      G G++ 
Sbjct: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GSGQSP 1126

Query: 308  GGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVI 359
            G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  S   
Sbjct: 1127 GHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQ 1182

Query: 360  LGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGGGKSA 416
             GS   H     + G    +SS  +  G+ S  S       SG    S     G G   +
Sbjct: 1183 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS 1242

Query: 417  DELGVGASGLNEFGETGLSGSEKG 440
               G   SGL      G  GS  G
Sbjct: 1243 PSRGRHGSGLGHSSSHGQHGSGSG 1266



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 110/452 (24%), Positives = 153/452 (33%), Gaps = 39/452 (8%)

Query: 28  GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS--RQRQDAGSPKSEDTPAGGFFNSSSS 85
           G   G SS G+  R     S  +G  G    +S    RQ +GS +S      G  +  SS
Sbjct: 261 GSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS 320

Query: 86  SGDSDRTKPFFSLGLG--------APGKAEDKSGDSQDAG----GSKSEDTPPGGFFYGS 133
           S     +   +S   G          G  + +SG  Q +G    GS S  +   G    +
Sbjct: 321 SHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGST 380

Query: 134 SSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG--NSRSEDSPAVGTGSSGLKLGAGKG 191
           S    S  +    S +  + G+ E  SR     G  +S S  SP  G   SG       G
Sbjct: 381 SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG 440

Query: 192 DAAFGFEVSDSNS-----------FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSEN 240
               GF  S S+            FG    SS+   G     SG   S   G    RS  
Sbjct: 441 QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQ 500

Query: 241 QFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFE 300
              G    +S  +    GQ G G  +  G+   GS S ++     G   S S + S    
Sbjct: 501 SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560

Query: 301 FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVIL 360
            G G  +  +   +     + SG     S+    +G G   + +G  ++ G    +    
Sbjct: 561 HGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620

Query: 361 GSSDQHEV---ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWS--------SDSGS 409
            S  QH     + S  G +   SS     G    GS  S S G   S           GS
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680

Query: 410 GGGGKSADELGVGASGLNE-FGETGLSGSEKG 440
           G G  S++      SG +  FG    SG   G
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSG 712



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 112/463 (24%), Positives = 158/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1903 RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1962

Query: 73   DT-PAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
               P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1963 SYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSA 2022

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 2023 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 2081

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 2082 GRHGSGSGRSSSSGQHGPG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2139

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S  +  +G     S       
Sbjct: 2140 SGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHG 2199

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2259

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 2260 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 2319

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 2320 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 2361



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 111/463 (23%), Positives = 159/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1433 RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1492

Query: 73   D-TPAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
              +P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1493 SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 1611

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 1612 GRHGSGSGRSSSSGQHGSG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S ++  +G             
Sbjct: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 1730 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 1789

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 1790 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 1849

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 1850 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 1891



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 115/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFG--SPGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S  +G    G ++     R  AGS +S     
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR 1364

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G     S S
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGCTQHGSGS 1421

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    ER  + +  S      G+GS       + G+G G 
Sbjct: 1422 GHSS------SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1475

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+   G  S          SG S S  LG    RS      G 
Sbjct: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ 1535

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 1592

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  
Sbjct: 1593 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-S 1648

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SGL      G  GS  G
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSG 1736



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 114/448 (25%), Positives = 158/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGS--PGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S   G    G ++  S  +Q +GS +S     
Sbjct: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G+    S S
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGYTQHGSGS 2361

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    ER  + +  S      G+GS       + G+G G 
Sbjct: 2362 GHSS------SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 2415

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+   G  S          SG   S  LG    RS      G 
Sbjct: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 2476 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 2532

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  
Sbjct: 2533 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-S 2588

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 2589 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 2648

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SGL      G  GS  G
Sbjct: 2649 SGQSPSRGRHGSGLGHSSSHGQHGSGSG 2676



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 113/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGS--PGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S   G    G ++  S  +Q +GS +S     
Sbjct: 1775 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 1834

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G+    S S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGYTQHGSGS 1891

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    E+  + +  S      G+GS       + G+G G 
Sbjct: 1892 GHSS------SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1945

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+G  G  S          SG   S  LG    RS      G 
Sbjct: 1946 SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2005

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 2006 HGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 2062

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G G+G+SS     E+SSG S  
Sbjct: 2063 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS-S 2118

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SG       G  GS  G
Sbjct: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSG 2206



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 102/452 (22%), Positives = 152/452 (33%), Gaps = 42/452 (9%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R     G   S      
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
            G   SSS      R+      G    G     +     +G          G   G SS+ 
Sbjct: 1264 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323

Query: 138  DSDKKKPLFSFEFG---------------ATGEDEDKSRERWDAGNSRSEDSPAVGTGS- 181
            D +      S  +G                 G  +  SR R  +G+  S      G+GS 
Sbjct: 1324 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1383

Query: 182  ---SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSFR 237
               S  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S +
Sbjct: 1384 WSSSSGRHGSGSGQSS-GFGHHESSSWQSSGCTQ------HGSGSGHSSSYEQHGSRSGQ 1436

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S 
Sbjct: 1437 SSRGERHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1493

Query: 298  LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
               +G G     +   +    S+ SG     S+    +G G   + +G  ++ G    + 
Sbjct: 1494 YSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553

Query: 358  VILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGNTWSSDSG 408
                S  QH     ++  + +  S   ++            SPG     SG     S   
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613

Query: 409  SGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
             G G   +   G   SGL E    G   S  G
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 104/453 (22%), Positives = 156/453 (34%), Gaps = 44/453 (9%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R    +G   S      
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS 2203

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS--------------KSED 123
            G   SSS      R+      G    G     S  SQ   GS              +S  
Sbjct: 2204 GSGRSSSRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSST 2262

Query: 124  TPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGT 179
                G   G SSS    G    +   +  +   +G+   + R    +G+S S      G+
Sbjct: 2263 FDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS 2322

Query: 180  G--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSF 236
            G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S 
Sbjct: 2323 GWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQHGSRSG 2375

Query: 237  RSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
            +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S
Sbjct: 2376 QSSRGERHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 2432

Query: 297  WLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDS 356
                +G G     +   +     + SG     S+    +G G   + +G  ++ G    +
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492

Query: 357  GVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGNTWSSDS 407
                 S  QH     ++  + +  S   ++            SPG     SG     S  
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552

Query: 408  GSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
              G G   +   G   SGL E    G   S  G
Sbjct: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 105/459 (22%), Positives = 159/459 (34%), Gaps = 56/459 (12%)

Query: 28   GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS----RQRQDAGSPKSEDTPAGGFFNSS 83
            G   G SS G+        S  +G  G    +S    RQ   +G   S      G  +SS
Sbjct: 1667 GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS 1726

Query: 84   S------SSGDSDRTKPFFSLGLGAPGKAEDKSGD------SQDAGGS------------ 119
            S       SG S    P+ S    +    + +SG       SQ   GS            
Sbjct: 1727 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1786

Query: 120  --KSEDTPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
              +S      G   G SSS    G    +   +  +   +G+   + R    +G+S S  
Sbjct: 1787 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYG 1846

Query: 174  SPAVGTG--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL 231
                G+G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S + 
Sbjct: 1847 QHGSGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQ 1899

Query: 232  -GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSS 290
             G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1956

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
             S + S    +G G     +   +     + SG     S+    +G G   + +G  ++ 
Sbjct: 1957 GSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016

Query: 351  GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGN 401
            G    +     S  QH     ++  + +  S   ++            SPG     SG  
Sbjct: 2017 GQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
               S    G G   +   G    GL E    G   S  G
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 117/470 (24%), Positives = 163/470 (34%), Gaps = 66/470 (14%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPL-----FSLEFGSPGETEDKS--RQRQDAGSPKSEDTP 75
            +S S G+    S SG   R +        S  +G  G    +S    RQ +GS  S    
Sbjct: 720  SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRV 779

Query: 76   AGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS 135
              G  +  SSS     +    S   G       +SG  Q +G  + E     G+    S+
Sbjct: 780  RHGSSSGHSSSHGQHGSGTSCSSSCG-----HYESGSGQASGFGQHESGSGQGYSQHGSA 834

Query: 136  SG--DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA 193
            SG   S  +    S +  ++G+ +  S +    G   S    A G G  G   G   G  
Sbjct: 835  SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894

Query: 194  AFGFEVSDSNSFG---------------------DTGISSKTVEGNQT------SSSGGS 226
              G     S S+G                      +G   K+  G  +      S SG S
Sbjct: 895  QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHS 954

Query: 227  VSIDL-GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA----- 280
             S +  G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     
Sbjct: 955  SSYEQHGSRSGQSSRSEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSR 1011

Query: 281  GFKGFGSDSSSSV-----EKSWL-----FEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
            G  G GS  SSS         W      +E G G + G      R   S+  G +G+SS 
Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
                +G   S+  +G  +S G    S     S  QH    S++ G  ++ S   +    S
Sbjct: 1072 HSSTHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ----S 1125

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
            PG     SG     S    G G   +   G   SGL E    G   S  G
Sbjct: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 73/260 (28%), Positives = 102/260 (39%), Gaps = 36/260 (13%)

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS-GQEGF 262
           S G+    S+ V G   S   G+ SI     S R   Q    G  NS S    S G++  
Sbjct: 133 SAGENDSYSRNVRG---SLKPGTESI-----SRRLSFQRDFSGQHNSYSGQSSSYGEQNS 184

Query: 263 GINEIGGNGMSGSVSAEA---GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNF---RD 316
             ++  G G  GS S ++   G  G GS  SSS +       G G++ G ++      + 
Sbjct: 185 DSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGS---GSGQSSGFSQHKSSSGQS 241

Query: 317 SGSNQSGDNGNSSKDFDGNGV--GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG 374
           SG +Q G     S  +  +G   G SS      +SSG S   G   GS  +  +   R G
Sbjct: 242 SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ-HGSGSRQSLGHGRQG 300

Query: 375 GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS----------DSGSG-GGGKSADELGVG- 422
              ++S      G+   GS  S S G   S           +SGSG   G    E G G 
Sbjct: 301 SGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ 357

Query: 423 ASGLNEFGETGLSGSEKGSH 442
           +SG ++ G      S +G H
Sbjct: 358 SSGYSKHGSGSGHSSSQGQH 377



>gi|57546919|tpd|FAA00004.1|   TPA: Hornerin [Homo sapiens]
          Length = 2850

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 121/471 (25%), Positives = 174/471 (36%), Gaps = 71/471 (15%)

Query: 17  KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
           + G+ +     G S GSSSS    G   R+    S      G++   SR R ++GS +S 
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556

Query: 73  DTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPG--GFF 130
                G+ +  SSS     +    S GLG       +S      G S    +  G  G  
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616

Query: 131 YGSSSS-----------------GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
            G SSS                 G    +   +  +   +G+   + R   D G+S S  
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYG 676

Query: 174 SPAVGTG--SSGLKLGAGKGDAA-FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
               G+G  SS    G+  G ++ FG +     S G +   S       + SSG      
Sbjct: 677 QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS-----GSSHSSGYRKHGS 731

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA---------- 280
               S RSE      GS + +S+ +  GQ G G ++  G+G  GS S  +          
Sbjct: 732 RSGQSSRSEQH----GSSSGLSSSY--GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785

Query: 281 ------GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-GDNGNSSKDFD 333
                 G  G G+  SSS      +E G G+  G   F   +SGS Q    +G++S  F 
Sbjct: 786 GHSSSHGQHGSGTSCSSSCGH---YESGSGQASG---FGQHESGSGQGYSQHGSASGHFS 839

Query: 334 GNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEA---GNLS 390
             G   S+  +G  +SSG  + S     S  QHE       G  +  S   ++   G   
Sbjct: 840 SQGRHGST--SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897

Query: 391 PGSDVSDSGGNTWSSDSGSGGG-GKSADELGVGASGLNEFGETGLSGSEKG 440
            GS  S S G       GSG G   S+   G G+   + FG    SG   G
Sbjct: 898 SGSGQSPSYGR-----HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 120/444 (27%), Positives = 155/444 (34%), Gaps = 48/444 (10%)

Query: 25   RSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSS 84
            R G  S  SSSSG  D      S +  S G+ E  S      G   S    + G     S
Sbjct: 843  RHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898

Query: 85   SSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGFFYGSSSSGDSDKKK 143
             SG S       S    +       SG  Q +G G KS      G+    S SG S   +
Sbjct: 899  GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                 + G+      +S +      S S  S + G   SG +   G G    G   S S 
Sbjct: 959  -----QHGSRSGQSSRSEQH----GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009

Query: 204  SFGDTGISS---------KTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNS 250
            S G  G  S         ++  G  +S     SG   S  LG    RS      G   +S
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 1069

Query: 251  ISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETK 307
              +    GQ G    +    G +G S   S+  G  G GS  SS   +      G G++ 
Sbjct: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GSGQSP 1126

Query: 308  GGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVI 359
            G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  S   
Sbjct: 1127 GHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQ 1182

Query: 360  LGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGGGKSA 416
             GS   H     + G    +SS  +  G+ S  S       SG    S     G G   +
Sbjct: 1183 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS 1242

Query: 417  DELGVGASGLNEFGETGLSGSEKG 440
               G   SGL      G  GS  G
Sbjct: 1243 PSRGRHGSGLGHSSSHGQHGSGSG 1266



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 110/452 (24%), Positives = 153/452 (33%), Gaps = 39/452 (8%)

Query: 28  GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS--RQRQDAGSPKSEDTPAGGFFNSSSS 85
           G   G SS G+  R     S  +G  G    +S    RQ +GS +S      G  +  SS
Sbjct: 261 GSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS 320

Query: 86  SGDSDRTKPFFSLGLG--------APGKAEDKSGDSQDAG----GSKSEDTPPGGFFYGS 133
           S     +   +S   G          G  + +SG  Q +G    GS S  +   G    +
Sbjct: 321 SHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGST 380

Query: 134 SSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG--NSRSEDSPAVGTGSSGLKLGAGKG 191
           S    S  +    S +  + G+ E  SR     G  +S S  SP  G   SG       G
Sbjct: 381 SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG 440

Query: 192 DAAFGFEVSDSNS-----------FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSEN 240
               GF  S S+            FG    SS+   G     SG   S   G    RS  
Sbjct: 441 QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQ 500

Query: 241 QFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFE 300
              G    +S  +    GQ G G  +  G+   GS S ++     G   S S + S    
Sbjct: 501 SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560

Query: 301 FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVIL 360
            G G  +  +   +     + SG     S+    +G G   + +G  ++ G    +    
Sbjct: 561 HGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620

Query: 361 GSSDQHEV---ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWS--------SDSGS 409
            S  QH     + S  G +   SS     G    GS  S S G   S           GS
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680

Query: 410 GGGGKSADELGVGASGLNE-FGETGLSGSEKG 440
           G G  S++      SG +  FG    SG   G
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSG 712



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 112/463 (24%), Positives = 158/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1903 RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1962

Query: 73   DT-PAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
               P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1963 SYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSA 2022

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 2023 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 2081

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 2082 GRHGSGSGRSSSSGQHGPG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2139

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S  +  +G     S       
Sbjct: 2140 SGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHG 2199

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2259

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 2260 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 2319

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 2320 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 2361



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 111/463 (23%), Positives = 159/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1433 RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1492

Query: 73   D-TPAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
              +P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1493 SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 1611

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 1612 GRHGSGSGRSSSSGQHGSG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S ++  +G             
Sbjct: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 1730 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 1789

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 1790 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 1849

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 1850 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 1891



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 115/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFG--SPGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S  +G    G ++     R  AGS +S     
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR 1364

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G     S S
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGCTQHGSGS 1421

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    ER  + +  S      G+GS       + G+G G 
Sbjct: 1422 GHSS------SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1475

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+   G  S          SG S S  LG    RS      G 
Sbjct: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ 1535

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 1592

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  
Sbjct: 1593 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-S 1648

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SGL      G  GS  G
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSG 1736



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 110/422 (26%), Positives = 154/422 (36%), Gaps = 21/422 (4%)

Query: 28   GFSYGSSSSGDLDRKKPLFSLEFGSPGET--EDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
            G S G SSS          S  +G  G    +  SR R  +GS  S      G  +  SS
Sbjct: 2267 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 2326

Query: 86   SGDSDRTKPFFSLGLGAPGKAE-DKSGDSQDAGGS-KSEDTPPGGFFYGSSSSGDSDKKK 143
            S     +    S G G    +    SG +Q   GS  S      G   G SS G+     
Sbjct: 2327 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSS 2386

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
               S  +G  G    +S      G S S  SP+   G  G   G     + +G     S+
Sbjct: 2387 SGSSSSYGQHGSGSRQSLGHGQHG-SGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSS 2445

Query: 204  SFG--DTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEG 261
            S G  ++G    +  G++ S SG S       +S    +     GS +  S+    GQ G
Sbjct: 2446 SRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS--SCGQHG 2503

Query: 262  FGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQ 321
                +   +G  GS S+++   G+G   S S +     + G G  +  +       G + 
Sbjct: 2504 ASSGQSSSHGQHGSGSSQSS--GYGRQGSGSGQSPGHSQRGSGSRQSPSY------GRHG 2555

Query: 322  SGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSS 381
            SG   +SS    G+G+G+SS     E+SSG S  S    GS   H     + G    +SS
Sbjct: 2556 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQHGSGSGHSSGYGQHGSRSGQSS 2614

Query: 382  DPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSE 438
              +  G+ S  S       SG    S     G G   +   G   SGL      G  GS 
Sbjct: 2615 RGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSG 2674

Query: 439  KG 440
             G
Sbjct: 2675 SG 2676



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 113/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGS--PGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S   G    G ++  S  +Q +GS +S     
Sbjct: 1775 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 1834

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G+    S S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGYTQHGSGS 1891

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    E+  + +  S      G+GS       + G+G G 
Sbjct: 1892 GHSS------SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1945

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+G  G  S          SG   S  LG    RS      G 
Sbjct: 1946 SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2005

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 2006 HGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 2062

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G G+G+SS     E+SSG S  
Sbjct: 2063 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS-S 2118

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SG       G  GS  G
Sbjct: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSG 2206



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 102/444 (22%), Positives = 155/444 (34%), Gaps = 39/444 (8%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R    +G   S      
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS 2203

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS--------------KSED 123
            G   SSS      R+      G    G     S  SQ   GS              +S  
Sbjct: 2204 GSGRSSSRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSST 2262

Query: 124  TPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGT 179
                G   G SSS    G    +   +  +   +G+   + R    +G+S S      G+
Sbjct: 2263 FDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS 2322

Query: 180  G--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSF 236
            G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S 
Sbjct: 2323 GWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQHGSRSG 2375

Query: 237  RSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
            +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S
Sbjct: 2376 QSSRGEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 2432

Query: 297  WLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDS 356
                +G G     +   +     + SG     S+    +G G   + +G  ++ G    +
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492

Query: 357  GVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSA 416
                 S  QH     ++  + +  S   +    S G     SG       S  G G + +
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQ----SSGYGRQGSGSGQSPGHSQRGSGSRQS 2548

Query: 417  DELGVGASGLNEFGETGLSGSEKG 440
               G   SG      +G  GS  G
Sbjct: 2549 PSYGRHGSGSGRSSSSGQHGSGLG 2572



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 102/452 (22%), Positives = 152/452 (33%), Gaps = 42/452 (9%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R     G   S      
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
            G   SSS      R+      G    G     +     +G          G   G SS+ 
Sbjct: 1264 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323

Query: 138  DSDKKKPLFSFEFG---------------ATGEDEDKSRERWDAGNSRSEDSPAVGTGS- 181
            D +      S  +G                 G  +  SR R  +G+  S      G+GS 
Sbjct: 1324 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1383

Query: 182  ---SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSFR 237
               S  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S +
Sbjct: 1384 WSSSSGRHGSGSGQSS-GFGHHESSSWQSSGCTQ------HGSGSGHSSSYEQHGSRSGQ 1436

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S 
Sbjct: 1437 SSRGERHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1493

Query: 298  LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
               +G G     +   +    S+ SG     S+    +G G   + +G  ++ G    + 
Sbjct: 1494 YSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553

Query: 358  VILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGNTWSSDSG 408
                S  QH     ++  + +  S   ++            SPG     SG     S   
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613

Query: 409  SGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
             G G   +   G   SGL E    G   S  G
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 105/459 (22%), Positives = 159/459 (34%), Gaps = 56/459 (12%)

Query: 28   GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS----RQRQDAGSPKSEDTPAGGFFNSS 83
            G   G SS G+        S  +G  G    +S    RQ   +G   S      G  +SS
Sbjct: 1667 GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS 1726

Query: 84   S------SSGDSDRTKPFFSLGLGAPGKAEDKSGD------SQDAGGS------------ 119
            S       SG S    P+ S    +    + +SG       SQ   GS            
Sbjct: 1727 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1786

Query: 120  --KSEDTPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
              +S      G   G SSS    G    +   +  +   +G+   + R    +G+S S  
Sbjct: 1787 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYG 1846

Query: 174  SPAVGTG--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL 231
                G+G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S + 
Sbjct: 1847 QHGSGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQ 1899

Query: 232  -GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSS 290
             G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1956

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
             S + S    +G G     +   +     + SG     S+    +G G   + +G  ++ 
Sbjct: 1957 GSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016

Query: 351  GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGN 401
            G    +     S  QH     ++  + +  S   ++            SPG     SG  
Sbjct: 2017 GQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
               S    G G   +   G    GL E    G   S  G
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 117/470 (24%), Positives = 163/470 (34%), Gaps = 66/470 (14%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPL-----FSLEFGSPGETEDKS--RQRQDAGSPKSEDTP 75
            +S S G+    S SG   R +        S  +G  G    +S    RQ +GS  S    
Sbjct: 720  SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRV 779

Query: 76   AGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS 135
              G  +  SSS     +    S   G       +SG  Q +G  + E     G+    S+
Sbjct: 780  RHGSSSGHSSSHGQHGSGTSCSSSCG-----HYESGSGQASGFGQHESGSGQGYSQHGSA 834

Query: 136  SG--DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA 193
            SG   S  +    S +  ++G+ +  S +    G   S    A G G  G   G   G  
Sbjct: 835  SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894

Query: 194  AFGFEVSDSNSFG---------------------DTGISSKTVEGNQT------SSSGGS 226
              G     S S+G                      +G   K+  G  +      S SG S
Sbjct: 895  QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHS 954

Query: 227  VSIDL-GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA----- 280
             S +  G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     
Sbjct: 955  SSYEQHGSRSGQSSRSEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSR 1011

Query: 281  GFKGFGSDSSSSV-----EKSWL-----FEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
            G  G GS  SSS         W      +E G G + G      R   S+  G +G+SS 
Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
                +G   S+  +G  +S G    S     S  QH    S++ G  ++ S   +    S
Sbjct: 1072 HSSTHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ----S 1125

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
            PG     SG     S    G G   +   G   SGL E    G   S  G
Sbjct: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 73/260 (28%), Positives = 102/260 (39%), Gaps = 36/260 (13%)

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS-GQEGF 262
           S G+    S+ V G   S   G+ SI     S R   Q    G  NS S    S G++  
Sbjct: 133 SAGENDSYSRNVRG---SLKPGTESI-----SRRLSFQRDFSGQHNSYSGQSSSYGEQNS 184

Query: 263 GINEIGGNGMSGSVSAEA---GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNF---RD 316
             ++  G G  GS S ++   G  G GS  SSS +       G G++ G ++      + 
Sbjct: 185 DSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGS---GSGQSSGFSQHKSSSGQS 241

Query: 317 SGSNQSGDNGNSSKDFDGNGV--GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG 374
           SG +Q G     S  +  +G   G SS      +SSG S   G   GS  +  +   R G
Sbjct: 242 SGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQ-HGSGSRQSLGHGRQG 300

Query: 375 GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS----------DSGSG-GGGKSADELGVG- 422
              ++S      G+   GS  S S G   S           +SGSG   G    E G G 
Sbjct: 301 SGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ 357

Query: 423 ASGLNEFGETGLSGSEKGSH 442
           +SG ++ G      S +G H
Sbjct: 358 SSGYSKHGSGSGHSSSQGQH 377



>gi|59939295|gb|AAX12417.1|   ifapsoriasin [Homo sapiens]
          Length = 2391

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 114/432 (26%), Positives = 155/432 (35%), Gaps = 69/432 (15%)

Query: 24   SRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSS 83
            SRSG  SYG    G         S +    G+    S Q    G  +     +  F    
Sbjct: 686  SRSGHSSYGQHGFG---------SSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHG 736

Query: 84   SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
            S SG S         G G  G     SG  Q +G  + E    G   YG  SSG S    
Sbjct: 737  SGSGQSS--------GFGQHG-----SGSGQSSGFGQHESRS-GQSSYGQHSSGSSQ--- 779

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                    ++G  +  SR+    G   S  S + G G    + G+G G +A GF    S 
Sbjct: 780  --------SSGYGQHGSRQTSGFGQHGSGSSQSTGFG----QYGSGSGQSA-GFGQHGSG 826

Query: 204  SFGDTGISSKTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS-G 258
            S   +G        +Q+S     SG S S   G     S  Q  G G   S S  +   G
Sbjct: 827  SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHG-SSSGQTSGFGQHRSSSGQYSGFG 885

Query: 259  QEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW---------LFEFGLGETKGG 309
            Q G G  +  G G  G+ S +  + GFG   S S + S+            +G   +  G
Sbjct: 886  QHGSGSGQSSGFGQHGTGSGQ--YSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 943

Query: 310  AEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVE 369
              F F   G ++SG   +S     G+G G SS     E+ SG S   G       QHE  
Sbjct: 944  QTFGF---GQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFG-------QHESR 993

Query: 370  LSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEF 429
             S++   +  S     +G    GS    + G  +     S G      + G G+   + F
Sbjct: 994  SSQSNYGQHGSGSSQSSGYGQHGSSSGQTTG--FGQHRSSSGQYSGFGQHGSGSDQSSGF 1051

Query: 430  GETGL-SGSEKG 440
            G+ G  SG   G
Sbjct: 1052 GQHGTGSGQSSG 1063



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 132/483 (27%), Positives = 177/483 (36%), Gaps = 89/483 (18%)

Query: 23  ASRSGGFS----YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           +S S  FS    YGS SS     ++    L   S G  +      Q  G  +S  + + G
Sbjct: 407 SSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSS-GFEQHVCGSGQTCGQHESTSSQSLG 465

Query: 79  FFNSSSSSGDSDRTKPFFSLGLGAP-----GKAEDKSGDSQDAGGSKSEDTPPGGFFYGS 133
           +    SSSG   +T  F   G G+      G+    SG S   G   S      GF    
Sbjct: 466 YDQHGSSSG---KTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHG 522

Query: 134 SSSGDSDKKKPLFSFEFGATGEDEDKSRE----RWDAGNSRSEDSPAVGT------GSSG 183
           S SG S              G+ E +SR+    +  +G+S+S      G+      G  G
Sbjct: 523 SVSGQSS-----------GFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHG 571

Query: 184 LKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG--------NQTS----SSGGSVSIDL 231
           L  G   G   +G     S+ FG  G  S    G         Q+S    SSG S S   
Sbjct: 572 LGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY 631

Query: 232 GDTSFRSENQFVGGGSLNSISNLWD-----SGQE-GFGINEIGGNGMSG----------S 275
           G    R  + F   GS +S S  +      SGQ  GFG +  G    SG          S
Sbjct: 632 GQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHS 691

Query: 276 VSAEAGF-----KGFGSDSSSSVEKSWLFEFGLGETKGG--AEFNFRDSGSNQSGDNG-N 327
              + GF      G+G   SSS + S    FG  E   G  + F    SGS QS   G +
Sbjct: 692 SYGQHGFGSSQSSGYGQHGSSSGQTS---GFGQHELSSGQSSSFGQHGSGSGQSSGFGQH 748

Query: 328 SSKDFDGNGVGDSSARNG----FENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDP 383
            S     +G G   +R+G     ++SSG S+ SG     S Q     S  G +   SS  
Sbjct: 749 GSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQ----TSGFGQHGSGSSQS 804

Query: 384 DEAGNLSPGSDVSDSGGNTWSSDSGSGGGGK--------SADELGVGASGLNEFGETGLS 435
              G    GS  S   G   S    S G G+        S  + G G+S  + +G+ G S
Sbjct: 805 TGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSS 864

Query: 436 GSE 438
             +
Sbjct: 865 SGQ 867



 Score = 67.4 bits (163), Expect = 2e-10
 Identities = 100/395 (25%), Positives = 136/395 (34%), Gaps = 45/395 (11%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKS-- 121
           Q +G  + E  P    + S    G  +  +P    G    G ++        +GGS+S  
Sbjct: 334 QPSGCGQPESNPCSQSY-SQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCS 392

Query: 122 ---EDTPPGGFFYGSSSSGDSDK-------KKPLFSFEFGATGEDEDKSRERWDAGNSR- 170
               +    G F  SSSS +  K            SFE   TG  +    E+   G+ + 
Sbjct: 393 NGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQT 452

Query: 171 -----SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG 225
                S  S ++G    G   G   G    G     S+ FG  G  S    G     S  
Sbjct: 453 CGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVS 512

Query: 226 SVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGF 285
             S   G     S  Q  G G   S S     GQ G G ++  G G  GS        GF
Sbjct: 513 GQSSGFGQHGSVS-GQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETS----GF 567

Query: 286 GSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNG 345
           G     S + +   ++G G  +    F    SGS QS            +G G   +R+G
Sbjct: 568 GQHGLGSGQSTGFGQYGSGSGQSSG-FGQHGSGSGQS------------SGFGQHESRSG 614

Query: 346 ----FENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
                ++SSG S+ SG     S Q     S  G +   SS     G    GS  S   G 
Sbjct: 615 QSSYGQHSSGSSQSSGYGQHGSRQ----TSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQ 670

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S    S G G+     G  + G + FG +  SG
Sbjct: 671 HVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSG 705



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 105/465 (22%), Positives = 151/465 (32%), Gaps = 50/465 (10%)

Query: 16   FKDGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQ-DAGSPKSEDT 74
            F   +  + +S GF    S SG         S    S G  + +SR  Q + G   S  +
Sbjct: 948  FGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSS 1007

Query: 75   PAGGFFNSSSSSGDSD-----RTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGF 129
             + G+    SSSG +      R+      G G  G   D+S      G    + +  G +
Sbjct: 1008 QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067

Query: 130  -------FYGSSSSGDSDK----KKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVG 178
                    YG   SG S      +    S +    G+    S +    G   S    + G
Sbjct: 1068 ESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSG 1127

Query: 179  TGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRS 238
             G  G   G   G A   +  S  +S+G  G  S    G     SG   +   G     S
Sbjct: 1128 FGQHGSGTGKSSGFAQHEYR-SGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGS 1186

Query: 239  ENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWL 298
            +N    G       ++ DSGQ         G G  GS S ++   G G   S  VE S  
Sbjct: 1187 DNFSSSG------QHISDSGQS-------TGFGQYGSGSGQS--TGLGQGESQQVE-SGS 1230

Query: 299  FEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGV 358
               G  ET  G   N     + +   +G       G+ V      +  ENS     DS V
Sbjct: 1231 TVHGRQETTHGQTIN-----TTRHSQSGQGQSTQTGSRVTRRRRSSQSENS-----DSEV 1280

Query: 359  ILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADE 418
                S +H   +    G+    S          G+     G  T    SG G     + +
Sbjct: 1281 HSKVSHRHSEHIHTQAGSHYPKS--GSTVRRRQGTTHGQRGDTTRHGHSGHG----QSTQ 1334

Query: 419  LGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETNAIIGQDINE 463
             G   SG   F  +  + SE  S +        +T++  G    E
Sbjct: 1335 TGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGE 1379



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 95/438 (21%), Positives = 153/438 (34%), Gaps = 78/438 (17%)

Query: 57  EDKSRQRQDAGSPKSEDTPA--GGFFNSSSSSGDSDRTKPFFSLGL-----GAPGKAEDK 109
           E++S   +D      EDTP    G+ +SS S G+        S G      G+  +   +
Sbjct: 110 EEESETEED-----EEDTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGR 164

Query: 110 SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGN- 168
            G+   +G  +           G S SG  D+            G    + RER +  + 
Sbjct: 165 QGNLSSSGNQEGSQKRYHRSSCGHSWSGGKDRH-----------GSSSVELRERINKSHI 213

Query: 169 ---SRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVS--DSNSF----------------GD 207
                S +    G+GS+  +   G G  + G E S  +SNS                 GD
Sbjct: 214 SPSRESGEEYESGSGSNSWER-KGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGD 272

Query: 208 TGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSG-QEGFGINE 266
           +G  S     + +S  G   +      S R   Q   G   + I +   SG + G G   
Sbjct: 273 SGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQ---GNQFSYIQSGCQSGIKGGQGHGC 329

Query: 267 IGGNGMSGSVSAEAG-------FKGFGSDSSS------------SVEKSWLFEFGLGETK 307
           + G   SG    E+         +G+G+  +             S + S   ++G G ++
Sbjct: 330 VSGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQ 389

Query: 308 GGAEFNFRDSGSNQSGDNGNSSKDF---DGNGVGDSSARNGFENSSGISEDSGVILGSSD 364
             +     + GS     N +SS +F   D  G G S + +  ++ +G+S+ SG      +
Sbjct: 390 SCSNGQ-HEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGF-----E 443

Query: 365 QHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
           QH     +T G  + +S      +    S    SG     S SG   G          +S
Sbjct: 444 QHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSS 503

Query: 425 GLNEFGETGLSGSEKGSH 442
           G  + G      S  G H
Sbjct: 504 GFGQHGSVSGQSSGFGQH 521



>gi|40795897|gb|AAR91619.1|   hornerin precursor [Homo sapiens]
          Length = 2850

 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 121/471 (25%), Positives = 174/471 (36%), Gaps = 71/471 (15%)

Query: 17  KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
           + G+ +     G S GSSSS    G   R+    S      G++   SR R ++GS +S 
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSS 556

Query: 73  DTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPG--GFF 130
                G+ +  SSS     +    S GLG       +S      G S    +  G  G  
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616

Query: 131 YGSSSS-----------------GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
            G SSS                 G    +   +  +   +G+   + R   D G+S S  
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYG 676

Query: 174 SPAVGTG--SSGLKLGAGKGDAA-FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
               G+G  SS    G+  G ++ FG +     S G +   S       + SSG      
Sbjct: 677 QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS-----GSSHSSGYRKHGS 731

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA---------- 280
               S RSE      GS + +S+ +  GQ G G ++  G+G  GS S  +          
Sbjct: 732 RSGQSSRSEQH----GSSSGLSSSY--GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSS 785

Query: 281 ------GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-GDNGNSSKDFD 333
                 G  G G+  SSS      +E G G+  G   F   +SGS Q    +G++S  F 
Sbjct: 786 GHSSSHGQHGSGTSCSSSCGH---YESGSGQASG---FGQHESGSGQGYSQHGSASGHFS 839

Query: 334 GNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEA---GNLS 390
             G   S+  +G  +SSG  + S     S  QHE       G  +  S   ++   G   
Sbjct: 840 SQGRHGST--SGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897

Query: 391 PGSDVSDSGGNTWSSDSGSGGG-GKSADELGVGASGLNEFGETGLSGSEKG 440
            GS  S S G       GSG G   S+   G G+   + FG    SG   G
Sbjct: 898 SGSGQSPSYGR-----HGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSG 943



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 111/452 (24%), Positives = 153/452 (33%), Gaps = 39/452 (8%)

Query: 28  GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS--RQRQDAGSPKSEDTPAGGFFNSSSS 85
           G   G SS GD  R     S  +G  G    +S    RQ +GS +S      G  +  SS
Sbjct: 261 GSRSGQSSRGDRHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSS 320

Query: 86  SGDSDRTKPFFSLGLG--------APGKAEDKSGDSQDAG----GSKSEDTPPGGFFYGS 133
           S     +   +S   G          G  + +SG  Q +G    GS S  +   G    +
Sbjct: 321 SHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGST 380

Query: 134 SSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG--NSRSEDSPAVGTGSSGLKLGAGKG 191
           S    S  +    S +  + G+ E  SR     G  +S S  SP  G   SG       G
Sbjct: 381 SGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSG 440

Query: 192 DAAFGFEVSDSNS-----------FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSEN 240
               GF  S S+            FG    SS+   G     SG   S   G    RS  
Sbjct: 441 QHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQ 500

Query: 241 QFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFE 300
              G    +S  +    GQ G G  +  G+   GS S ++     G   S S + S    
Sbjct: 501 SSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGP 560

Query: 301 FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVIL 360
            G G  +  +   +     + SG     S+    +G G   + +G  ++ G    +    
Sbjct: 561 HGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 620

Query: 361 GSSDQHEV---ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWS--------SDSGS 409
            S  QH     + S  G +   SS     G    GS  S S G   S           GS
Sbjct: 621 SSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGS 680

Query: 410 GGGGKSADELGVGASGLNE-FGETGLSGSEKG 440
           G G  S++      SG +  FG    SG   G
Sbjct: 681 GSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSG 712



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 120/444 (27%), Positives = 155/444 (34%), Gaps = 48/444 (10%)

Query: 25   RSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSS 84
            R G  S  SSSSG  D      S +  S G+ E  S      G   S    + G     S
Sbjct: 843  RHGSTSGQSSSSGQHDSS----SGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGS 898

Query: 85   SSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGFFYGSSSSGDSDKKK 143
             SG S       S    +       SG  Q +G G KS      G+    S SG S   +
Sbjct: 899  GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958

Query: 144  PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                 + G+      +S +      S S  S + G   SG +   G G    G   S S 
Sbjct: 959  -----QHGSRSGQSSRSEQH----GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009

Query: 204  SFGDTGISS---------KTVEGNQTS----SSGGSVSIDLGDTSFRSENQFVGGGSLNS 250
            S G  G  S         ++  G  +S     SG   S  LG    RS      G   +S
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 1069

Query: 251  ISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETK 307
              +    GQ G    +    G +G S   S+  G  G GS  SS   +      G G++ 
Sbjct: 1070 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GSGQSP 1126

Query: 308  GGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVI 359
            G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  S   
Sbjct: 1127 GHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-SSYSQ 1182

Query: 360  LGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGGGKSA 416
             GS   H     + G    +SS  +  G+ S  S       SG    S     G G   +
Sbjct: 1183 HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS 1242

Query: 417  DELGVGASGLNEFGETGLSGSEKG 440
               G   SGL      G  GS  G
Sbjct: 1243 PSRGRHGSGLGHSSSHGQHGSGSG 1266



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 112/463 (24%), Positives = 158/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1903 RSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1962

Query: 73   DT-PAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
               P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1963 SYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSA 2022

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 2023 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 2081

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 2082 GRHGSGSGRSSSSGQHGPG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 2139

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S  +  +G     S       
Sbjct: 2140 SGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHG 2199

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2259

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 2260 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 2319

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 2320 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 2361



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 111/463 (23%), Positives = 159/463 (34%), Gaps = 42/463 (9%)

Query: 17   KDGKIAASRSGGFSYGSSSS----GDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE 72
            + G+ +     G S GSSSS    G   R+           G++   SR R  +GS +S 
Sbjct: 1433 RSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 1492

Query: 73   D-TPAGGFFNSSSSSGDSD------------RTKPFFSLGLGAPGKAEDKSGDSQDAGGS 119
              +P G     SSS G  +             ++   S G G  G +   S      G +
Sbjct: 1493 SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552

Query: 120  KSEDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAV 177
              + +  G  G   G SSS          S  +G  G    +S      G S S  SP+ 
Sbjct: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRG-SGSRQSPSY 1611

Query: 178  GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
            G   SG    +  G    G  + +S+ FG    SS          SG   S   G    R
Sbjct: 1612 GRHGSGSGRSSSSGQHGSG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR 1669

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S     G    +S  +    GQ G G  +  G+G  GS S ++  +G             
Sbjct: 1670 SGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729

Query: 298  LFEFGLGETKGGAEFNFRDS-----GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
                G G +     +  R       G ++SG   +S+    G+G G   ++    ++SG 
Sbjct: 1730 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 1789

Query: 353  S---EDSGVILGSSDQH------EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----- 398
            S   +  G   G S  H        + S  G     S      G    GS  S S     
Sbjct: 1790 SSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHG 1849

Query: 399  GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
             G+ WSS SG  G G S    G G    + +  +G +    GS
Sbjct: 1850 SGSGWSSSSGRHGSG-SGQSSGFGHHESSSWQSSGYTQHGSGS 1891



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 115/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFG--SPGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S  +G    G ++     R  AGS +S     
Sbjct: 1305 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGR 1364

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G     S S
Sbjct: 1365 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGCTQHGSGS 1421

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    ER  + +  S      G+GS       + G+G G 
Sbjct: 1422 GHSS------SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1475

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+   G  S          SG S S  LG    RS      G 
Sbjct: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ 1535

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 1536 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 1592

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  
Sbjct: 1593 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-S 1648

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SGL      G  GS  G
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHGSGSG 1736



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 114/448 (25%), Positives = 158/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGS--PGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S   G    G ++  S  +Q +GS +S     
Sbjct: 2245 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 2304

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G+    S S
Sbjct: 2305 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGYTQHGSGS 2361

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    ER  + +  S      G+GS       + G+G G 
Sbjct: 2362 GHSS------SYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 2415

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+   G  S          SG   S  LG    RS      G 
Sbjct: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 2476 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 2532

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G+G+G+SS     E+SSG S  
Sbjct: 2533 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS-S 2588

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 2589 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 2648

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SGL      G  GS  G
Sbjct: 2649 SGQSPSRGRHGSGLGHSSSHGQHGSGSG 2676



 Score = 71.6 bits (174), Expect = 9e-12
 Identities = 113/448 (25%), Positives = 157/448 (35%), Gaps = 42/448 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGS--PGETEDKSRQRQDAGSPKSEDTPA 76
            G   +    G + G SS+ D +      S   G    G ++  S  +Q +GS +S     
Sbjct: 1775 GHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGR 1834

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             G  +  SSS     +   +S   G  G     SG S   G  +S      G+    S S
Sbjct: 1835 HGSGSGHSSSYGQHGSGSGWSSSSGRHGSG---SGQSSGFGHHESSSWQSSGYTQHGSGS 1891

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL----KLGAGKGD 192
            G S       S+E   +   +    E+  + +  S      G+GS       + G+G G 
Sbjct: 1892 GHSS------SYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQ 1945

Query: 193  AA------FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
            +        G     S+S+G  G  S          SG   S  LG    RS      G 
Sbjct: 1946 SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2005

Query: 247  SLNSISNLWDSGQEGFGINE---IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
              +S  +    GQ G    +    G +G S   S+  G  G GS  SS   +      G 
Sbjct: 2006 HGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS---GS 2062

Query: 304  GETKGGAEFNFRDSGSNQS--------GDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
            G++ G  +   R SGS QS        G   +SS    G G+G+SS     E+SSG S  
Sbjct: 2063 GQSPGHGQ---RGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQS-S 2118

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD---VSDSGGNTWSSDSGSGGG 412
            S    GS   H     + G    +SS  +  G+ S  S       SG    S     G G
Sbjct: 2119 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSG 2178

Query: 413  GKSADELGVGASGLNEFGETGLSGSEKG 440
               +   G   SG       G  GS  G
Sbjct: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSG 2206



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 102/452 (22%), Positives = 152/452 (33%), Gaps = 42/452 (9%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R     G   S      
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGS 1263

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG 137
            G   SSS      R+      G    G     +     +G          G   G SS+ 
Sbjct: 1264 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1323

Query: 138  DSDKKKPLFSFEFG---------------ATGEDEDKSRERWDAGNSRSEDSPAVGTGS- 181
            D +      S  +G                 G  +  SR R  +G+  S      G+GS 
Sbjct: 1324 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSG 1383

Query: 182  ---SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSFR 237
               S  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S +
Sbjct: 1384 WSSSSGRHGSGSGQSS-GFGHHESSSWQSSGCTQ------HGSGSGHSSSYEQHGSRSGQ 1436

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
            S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S 
Sbjct: 1437 SSRGERHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSS 1493

Query: 298  LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
               +G G     +   +    S+ SG     S+    +G G   + +G  ++ G    + 
Sbjct: 1494 YSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS 1553

Query: 358  VILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGNTWSSDSG 408
                S  QH     ++  + +  S   ++            SPG     SG     S   
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613

Query: 409  SGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
             G G   +   G   SGL E    G   S  G
Sbjct: 1614 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1645



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 104/453 (22%), Positives = 156/453 (34%), Gaps = 44/453 (9%)

Query: 19   GKIAASRSGGFS-YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAG 77
            G+   S SG  S YG   SG   R+      +    G +  + R    +G   S      
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGS--RQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGS 2203

Query: 78   GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS--------------KSED 123
            G   SSS      R+      G    G     S  SQ   GS              +S  
Sbjct: 2204 GSGRSSSRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSST 2262

Query: 124  TPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGT 179
                G   G SSS    G    +   +  +   +G+   + R    +G+S S      G+
Sbjct: 2263 FDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGS 2322

Query: 180  G--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL-GDTSF 236
            G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S +  G  S 
Sbjct: 2323 GWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQHGSRSG 2375

Query: 237  RSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
            +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S S + S
Sbjct: 2376 QSSRGERHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSS 2432

Query: 297  WLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDS 356
                +G G     +   +     + SG     S+    +G G   + +G  ++ G    +
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492

Query: 357  GVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGNTWSSDS 407
                 S  QH     ++  + +  S   ++            SPG     SG     S  
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552

Query: 408  GSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
              G G   +   G   SGL E    G   S  G
Sbjct: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 105/459 (22%), Positives = 159/459 (34%), Gaps = 56/459 (12%)

Query: 28   GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKS----RQRQDAGSPKSEDTPAGGFFNSS 83
            G   G SS G+        S  +G  G    +S    RQ   +G   S      G  +SS
Sbjct: 1667 GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSS 1726

Query: 84   S------SSGDSDRTKPFFSLGLGAPGKAEDKSGD------SQDAGGS------------ 119
            S       SG S    P+ S    +    + +SG       SQ   GS            
Sbjct: 1727 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1786

Query: 120  --KSEDTPPGGFFYGSSSS----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
              +S      G   G SSS    G    +   +  +   +G+   + R    +G+S S  
Sbjct: 1787 SGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYG 1846

Query: 174  SPAVGTG--SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL 231
                G+G  SS  + G+G G ++ GF   +S+S+  +G +         S SG S S + 
Sbjct: 1847 QHGSGSGWSSSSGRHGSGSGQSS-GFGHHESSSWQSSGYTQ------HGSGSGHSSSYEQ 1899

Query: 232  -GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSS 290
             G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     G   S
Sbjct: 1900 HGSRSGQSSRGEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS 1956

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
             S + S    +G G     +   +     + SG     S+    +G G   + +G  ++ 
Sbjct: 1957 GSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 2016

Query: 351  GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL---------SPGSDVSDSGGN 401
            G    +     S  QH     ++  + +  S   ++            SPG     SG  
Sbjct: 2017 GQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR 2076

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
               S    G G   +   G    GL E    G   S  G
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSG 2115



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 117/470 (24%), Positives = 163/470 (34%), Gaps = 66/470 (14%)

Query: 23   ASRSGGFSYGSSSSGDLDRKKPL-----FSLEFGSPGETEDKS--RQRQDAGSPKSEDTP 75
            +S S G+    S SG   R +        S  +G  G    +S    RQ +GS  S    
Sbjct: 720  SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRV 779

Query: 76   AGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS 135
              G  +  SSS     +    S   G       +SG  Q +G  + E     G+    S+
Sbjct: 780  RHGSSSGHSSSHGQHGSGTSCSSSCG-----HYESGSGQASGFGQHESGSGQGYSQHGSA 834

Query: 136  SG--DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA 193
            SG   S  +    S +  ++G+ +  S +    G   S    A G G  G   G   G  
Sbjct: 835  SGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894

Query: 194  AFGFEVSDSNSFG---------------------DTGISSKTVEGNQT------SSSGGS 226
              G     S S+G                      +G   K+  G  +      S SG S
Sbjct: 895  QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHS 954

Query: 227  VSIDL-GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA----- 280
             S +  G  S +S      G S  S S+    GQ G G  +  G+G  GS S ++     
Sbjct: 955  SSYEQHGSRSGQSSRSEQHGSSSGSSSSY---GQHGSGSRQSLGHGQHGSGSGQSPSPSR 1011

Query: 281  GFKGFGSDSSSSV-----EKSWL-----FEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
            G  G GS  SSS         W      +E G G + G      R   S+  G +G+SS 
Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG 1071

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
                +G   S+  +G  +S G    S     S  QH    S++ G  ++ S   +    S
Sbjct: 1072 HSSTHGQHGST--SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ----S 1125

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
            PG     SG     S    G G   +   G   SGL E    G   S  G
Sbjct: 1126 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 1175



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 73/260 (28%), Positives = 103/260 (39%), Gaps = 36/260 (13%)

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS-GQEGF 262
           S G+    S+ V G   S   G+ SI     S R   Q    G  NS S    S G++  
Sbjct: 133 SAGENDSYSRNVRG---SLKPGTESI-----SRRLSFQRDFSGQHNSYSGQSSSYGEQNS 184

Query: 263 GINEIGGNGMSGSVSAEA---GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNF---RD 316
             ++  G G  GS S ++   G  G GS  SSS +       G G++ G ++      + 
Sbjct: 185 DSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGS---GSGQSSGFSQHKSSSGQS 241

Query: 317 SGSNQSGDNGNSSKDFDGNGV--GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG 374
           SG +Q G     S  +  +G   G SS  +   +SSG S   G   GS  +  +   R G
Sbjct: 242 SGYSQHGSGSGHSSGYGQHGSRSGQSSRGDRHRSSSGSSSSYGQ-HGSGSRQSLGHGRQG 300

Query: 375 GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS----------DSGSG-GGGKSADELGVG- 422
              ++S      G+   GS  S S G   S           +SGSG   G    E G G 
Sbjct: 301 SGSRQSPSHVRHGS---GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ 357

Query: 423 ASGLNEFGETGLSGSEKGSH 442
           +SG ++ G      S +G H
Sbjct: 358 SSGYSKHGSGSGHSSSQGQH 377



>gi|186398|gb|AAA59164.1|   MUC2
          Length = 984

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 64/252 (25%), Positives = 104/252 (41%), Gaps = 31/252 (12%)

Query: 636 VSMPPNQF-TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS-----CPKGNP 689
           V +P ++F  +T G CG+  N   DD +     +    +A A+ W +       CP  + 
Sbjct: 412 VRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSS 471

Query: 690 SS---CISI--------EKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC 738
           ++    +++         K+      C ++ DS    A CH +V P+ Y++ C   +C  
Sbjct: 472 TTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSL--FAQCHALVPPQHYYDACVFDSCFM 529

Query: 739 ENSQDCLCTILGNYVKACAEKETYIVGWRT---GLCEHSCPSGLVFKYNVKACNSSCRSL 795
             S    C  L  Y   CA+ +   + WR    G C   CPS   ++    A   +C+S 
Sbjct: 530 PGSS-LECASLQAYAALCAQ-QNICLDWRNHTHGACLVECPSHREYQACGPAEEPTCKSS 587

Query: 796 SERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP-GKLIHIDDNKC 854
           S +  +     V V+GC CP+       G  V    C C   D V +  G+    D   C
Sbjct: 588 SSQQNNT----VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNC 643

Query: 855 VCRDG--ILLCQ 864
           VC +G   ++CQ
Sbjct: 644 VCLEGGSGIICQ 655



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 46/184 (25%), Positives = 68/184 (36%), Gaps = 24/184 (13%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT----------SQECSDTVAQTFPCD- 1023
            G CG       DD       + S      + W            S   +   A T P   
Sbjct: 425  GQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGG 484

Query: 1024 -SNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
             + P+        C++++DS F  CH  V P  Y+D C+ ++C   M G  L  C ++  
Sbjct: 485  KTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCF--MPGSSLE-CASLQA 541

Query: 1083 YAEACSAVGVCVSWRK--PNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YA  C+   +C+ WR      C V C  +         Y+ CG     TCK     Q  +
Sbjct: 542  YAALCAQQNICLDWRNHTHGACLVECPSHR-------EYQACGPAEEPTCKSSSSQQNNT 594

Query: 1141 SLLE 1144
             L+E
Sbjct: 595  VLVE 598



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 5/111 (4%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I  + F +C  +    + Y   C+ + C     +  C +    + LCA         
Sbjct: 498 CQLIKDSLFAQCHALVPPQHYYDA-CVFDSCFMPGSSLECASLQAYAALCAQQN--ICLD 554

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSE-CVSGCTCPE 601
           WR+ +   C  + CP    Y+ CGP+   TC + +  Q++   V GC CPE
Sbjct: 555 WRNHTHGACLVE-CPSHREYQACGPAEEPTCKSSSSQQNNTVLVEGCFCPE 604



>gi|2130546|gb|AAC51344.1|   mucin [Homo sapiens]
          Length = 644

 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 47/184 (25%), Positives = 70/184 (38%), Gaps = 27/184 (14%)

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSD----------TVAQTFPCD 1023
            CG C NN    +DD   R  + A+   +   +W       D          T +   P  
Sbjct: 442  CGTCTNNQ---RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVS 498

Query: 1024 SNPYCKAWAVRK-CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
            S P       +  C+++    F +CHN V P  + + CI + C     G+    C ++  
Sbjct: 499  STPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLER 554

Query: 1083 YAEACSAVGVCVSWR--KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YAE C A GVC  WR     LC + C            Y+PCG +   TC  +    +  
Sbjct: 555  YAELCRARGVCSDWRGATGGLCDLTCPPTKV-------YKPCGPIQPATCNSRNQSPQLE 607

Query: 1141 SLLE 1144
             + E
Sbjct: 608  GMAE 611



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 37/120 (30%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C+ ++   F +C  +      +   CI ++C+ R +   C +    + LC + G      
Sbjct: 512 CDLMLSQVFAECHNLVP-PGPFFNACISDHCRGRLEVP-CQSLERYAELCRARG--VCSD 567

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATCS--NVAPFQDSECVSGCTCPEDKIQIFNA 609
           WR  +  +C    CP   +YK CGP  PATC+  N +P Q      GC CPE++I +FNA
Sbjct: 568 WRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPENQI-LFNA 624



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 49/208 (23%), Positives = 83/208 (39%), Gaps = 29/208 (13%)

Query: 645 DTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC------------PKGNPSSC 692
           +T G CG+  N   DD +        + +  A +W +               P  +P++ 
Sbjct: 437 NTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAP 496

Query: 693 ISIEKEKF---AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
           +S          +  C ++L  S   A CH +V P P+   C   +  C    +  C  L
Sbjct: 497 VSSTPTPTPCPPQPLCDLML--SQVFAECHNLVPPGPFFNAC--ISDHCRGRLEVPCQSL 552

Query: 750 GNYVKACAEKETYIVGWR---TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             Y + C  +      WR    GLC+ +CP   V+K       ++C S   R++S  +E 
Sbjct: 553 ERYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 608

Query: 807 VPVDGCTCPD--AMYQNNEGNCVLKSQC 832
           +  +GC CP+   ++  + G CV    C
Sbjct: 609 M-AEGCFCPENQILFNAHMGICVQACPC 635



>gi|2370133|emb|CAA70926.1|   mucin [Homo sapiens]
          Length = 845

 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 47/184 (25%), Positives = 70/184 (38%), Gaps = 27/184 (14%)

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSD----------TVAQTFPCD 1023
            CG C NN    +DD   R  + A+   +   +W       D          T +   P  
Sbjct: 304  CGTCTNNQ---RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVS 360

Query: 1024 SNPYCKAWAVRK-CEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1082
            S P       +  C+++    F +CHN V P  + + CI + C     G+    C ++  
Sbjct: 361  STPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEA 416

Query: 1083 YAEACSAVGVCVSWR--KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFS 1140
            YAE C A GVC  WR     LC + C            Y+PCG +   TC  +    +  
Sbjct: 417  YAELCRARGVCSDWRGATGGLCDLTCPPTKV-------YKPCGPIQPATCNSRNQSPQLE 469

Query: 1141 SLLE 1144
             + E
Sbjct: 470  GMAE 473



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C+ ++   F +C  +      +   CI ++C+ R +   C +    + LC + G      
Sbjct: 374 CDLMLSQVFAECHNLVP-PGPFFNACISDHCRGRLEVP-CQSLEAYAELCRARG--VCSD 429

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATCS--NVAPFQDSECVSGCTCPEDKIQIFNA 609
           WR  +  +C    CP   +YK CGP  PATC+  N +P Q      GC CPED+I +FNA
Sbjct: 430 WRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPEDQI-LFNA 486



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 58/241 (24%), Positives = 97/241 (40%), Gaps = 32/241 (13%)

Query: 645 DTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC------------PKGNPSSC 692
           +T G CG+  N   DD +        + +  A +W +               P  +P++ 
Sbjct: 299 NTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAP 358

Query: 693 ISIEKEKF---AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
           +S          +  C ++L  S   A CH +V P P+   C   +  C    +  C  L
Sbjct: 359 VSSTPTPTPCPPQPLCDLML--SQVFAECHNLVPPGPFFNAC--ISDHCRGRLEVPCQSL 414

Query: 750 GNYVKACAEKETYIVGWR---TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             Y + C  +      WR    GLC+ +CP   V+K       ++C S   R++S  +E 
Sbjct: 415 EAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 470

Query: 807 VPVDGCTCPD--AMYQNNEGNCVLKSQCDCYINDEVMQ-PGKLIHIDDNKCVCRDGILLC 863
           +  +GC CP+   ++  + G CV    C C   D   + PG+    +   CVC +G +  
Sbjct: 471 M-AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSV 527

Query: 864 Q 864
           Q
Sbjct: 528 Q 528



>gi|2290534|gb|AAB65151.1|   sublingual gland mucin [Homo sapiens]
          Length = 879

 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 46/186 (24%), Positives = 70/186 (37%), Gaps = 31/186 (16%)

Query: 974  CGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSD----------TVAQTFPCD 1023
            CG C NN    +DD   R  + A+   +   +W       D          T +   P  
Sbjct: 354  CGTCTNNQ---RDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVS 410

Query: 1024 SNPY---CKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1080
            S P    C    +  C+++    F +CH  + P  + + CI + C     G+    C ++
Sbjct: 411  STPTPTPCPPQLL--CDLMLSQVFAECHTLLPPGPFFNACISDHC----RGRLEVPCQSL 464

Query: 1081 AMYAEACSAVGVCVSWR--KPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1138
              YAE C A GVC  WR     LC + C            Y+PCG +   TC  +    +
Sbjct: 465  EAYAELCRARGVCSDWRGATGGLCDLTCPPTKV-------YKPCGPIQPATCNSRNQSPQ 517

Query: 1139 FSSLLE 1144
               + E
Sbjct: 518  LEGMAE 523



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C+ ++   F +C  +      +   CI ++C+ R +   C +    + LC + G      
Sbjct: 424 CDLMLSQVFAECHTLLP-PGPFFNACISDHCRGRLEVP-CQSLEAYAELCRARG--VCSD 479

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATCS--NVAPFQDSECVSGCTCPEDKIQIFNA 609
           WR  +  +C    CP   +YK CGP  PATC+  N +P Q      GC CPED+I +FNA
Sbjct: 480 WRGATGGLCDLT-CPPTKVYKPCGPIQPATCNSRNQSP-QLEGMAEGCFCPEDQI-LFNA 536



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 57/241 (23%), Positives = 97/241 (40%), Gaps = 32/241 (13%)

Query: 645 DTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSC------------PKGNPSSC 692
           +T G CG+  N   DD +        + +  A +W +               P  +P++ 
Sbjct: 349 NTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAP 408

Query: 693 ISIEKEKF---AERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTIL 749
           +S          +  C ++L  S   A CH ++ P P+   C   +  C    +  C  L
Sbjct: 409 VSSTPTPTPCPPQLLCDLML--SQVFAECHTLLPPGPFFNAC--ISDHCRGRLEVPCQSL 464

Query: 750 GNYVKACAEKETYIVGWR---TGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 806
             Y + C  +      WR    GLC+ +CP   V+K       ++C S   R++S  +E 
Sbjct: 465 EAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RNQSPQLEG 520

Query: 807 VPVDGCTCPD--AMYQNNEGNCVLKSQCDCYINDEVMQ-PGKLIHIDDNKCVCRDGILLC 863
           +  +GC CP+   ++  + G CV    C C   D   + PG+    +   CVC +G +  
Sbjct: 521 M-AEGCFCPEDQILFNAHMGICV--QACPCVGPDGFPKFPGERWVSNCQSCVCDEGSVSV 577

Query: 864 Q 864
           Q
Sbjct: 578 Q 578



>gi|51464403|ref|XP_068121.3|   PREDICTED: similar to CG15920-PB [Homo sapiens]
          Length = 553

 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 82/377 (21%), Positives = 149/377 (39%), Gaps = 35/377 (9%)

Query: 51  GSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS 110
           G+ GE+ ++   R   GS    ++     ++ + + G+S   + +   G G  G++  + 
Sbjct: 190 GTDGESLER---RGYHGSDTDRESLERRGYHGNGTDGESSEHRGYH--GNGTDGESLGRP 244

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G  ++  G+  E++   G+ +G+ + G+S +++      +   G D + S  R   GN  
Sbjct: 245 GYHRN--GTDGENSERRGY-HGNGTDGESSERRG-----YHGNGTDGESSGRRGYHGNGT 296

Query: 171 SEDSPAV----GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGS 226
             +S       G G+ G   G  +G    G +  +S+    TG    TV+  + S     
Sbjct: 297 DGESSGRRGYHGNGTDGESSGC-RGYHGNGTD-GESSEMAPTGRVQNTVDILEMSLEHRG 354

Query: 227 VSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG 286
                 D        + G G+         SG+ G+      GNG  G  S   G+ G G
Sbjct: 355 YHGSGTDGESSGRRGYHGNGTDGE-----SSGRRGYH-----GNGTDGESSGRRGYHGNG 404

Query: 287 SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGV-GDSSARNG 345
           +D  SS  + +      GE+ G   ++   +    SG  G     + GNG  G+SS R G
Sbjct: 405 TDGESSGRRGYHGNGTDGESSGRPGYHGNGTDGESSGRRG-----YHGNGTDGESSGRRG 459

Query: 346 FENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
           +  +    E SG      +  + E S   G     +D + +G      + +D   +    
Sbjct: 460 YHGNGTDGESSGRRGYHGNGTDGESSGRRGYHGNGTDGESSGRRGYHGNGTDGESSGRRG 519

Query: 406 DSGSGGGGKSADELGVG 422
             G+G  G+S++    G
Sbjct: 520 YHGNGTDGESSEMAPTG 536



>gi|54035079|gb|AAH34690.1|   Loricrin [Homo sapiens]
          Length = 316

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 72/263 (27%), Positives = 84/263 (31%), Gaps = 10/263 (3%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G G  G   G G G  + G   S     G  G S     G  +   GG      G  S  
Sbjct: 30  GGGGCGFFGGGGSGGGSSG---SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS    S  + SG  G G    GG G SG  S      G GS        S 
Sbjct: 87  SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG----SG 142

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
            F  G G   G A       G +  G +G  S  F   G G S        S G S   G
Sbjct: 143 CFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGGGSGCGG 202

Query: 358 VILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSAD 417
              G S    V  S+       +  P   G  S G      G   +SS  G G  G    
Sbjct: 203 GSSGGSGSGYVS-SQQVTQTSCAPQPSYGGGSSGGG--GSGGSGCFSSGGGGGSSGCGGG 259

Query: 418 ELGVGASGLNEFGETGLSGSEKG 440
             G+G+  +   G +   G   G
Sbjct: 260 SSGIGSGCIISGGGSVCGGGSSG 282



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 49/169 (28%), Positives = 54/169 (31%), Gaps = 37/169 (21%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG G  G      GF G G     S      +  G G + GG        G   SG  G 
Sbjct: 22  GGGGGGGGGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGC-------GGGSSGGGGG 74

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
                 G G G S   +G   SSG                      GG+   SS    +G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSG----------------------GGSGCFSSGGGGSG 112

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S G   S  GG   S    SGGGG S      G SG    G  G SG
Sbjct: 113 CFSSGGGGSSGGG---SGCFSSGGGGSSG-----GGSGCFSSGGGGFSG 153



>gi|4557725|ref|NP_000418.1|   loricrin [Homo sapiens]
 gi|2144802|pir||A38743   loricrin - human
 gi|126389|sp|P23490|LORI_HUMAN   Loricrin
 gi|187187|gb|AAA36181.1|   loricrin
 gi|187185|gb|AAA36180.1|   loricrin
          Length = 316

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 72/263 (27%), Positives = 84/263 (31%), Gaps = 10/263 (3%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G G  G   G G G  + G   S     G  G S     G  +   GG      G  S  
Sbjct: 30  GGGGCGFFGGGGSGGGSSG---SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS    S  + SG  G G    GG G SG  S      G GS        S 
Sbjct: 87  SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG----SG 142

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
            F  G G   G A       G +  G +G  S  F   G G S        S G S   G
Sbjct: 143 CFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGGGSGCGG 202

Query: 358 VILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSAD 417
              G S    V  S+       +  P   G  S G      G   +SS  G G  G    
Sbjct: 203 GSSGGSGSGYVS-SQQVTQTSCAPQPSYGGGSSGGG--GSGGSGCFSSGGGGGSSGCGGG 259

Query: 418 ELGVGASGLNEFGETGLSGSEKG 440
             G+G+  +   G +   G   G
Sbjct: 260 SSGIGSGCIISGGGSVCGGGSSG 282



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 49/169 (28%), Positives = 55/169 (32%), Gaps = 37/169 (21%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG G  G+     GF G G     S      +  G G + GG        G   SG  G 
Sbjct: 22  GGGGGGGTGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGC-------GGGSSGGGGG 74

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
                 G G G S   +G   SSG                      GG+   SS    +G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSG----------------------GGSGCFSSGGGGSG 112

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S G   S  GG   S    SGGGG S      G SG    G  G SG
Sbjct: 113 CFSSGGGGSSGGG---SGCFSSGGGGSSG-----GGSGCFSSGGGGFSG 153



>gi|49168594|emb|CAG38792.1|   LOR [Homo sapiens]
          Length = 316

 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 72/263 (27%), Positives = 84/263 (31%), Gaps = 10/263 (3%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G G  G   G G G  + G   S     G  G S     G  +   GG      G  S  
Sbjct: 30  GGGGCGFFGGGGSGGGSSG---SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS    S  + SG  G G    GG G SG  S      G GS        S 
Sbjct: 87  SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG----SG 142

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
            F  G G   G A       G +  G +G  S  F   G G S        S G S   G
Sbjct: 143 CFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGGGSGCGG 202

Query: 358 VILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSAD 417
              G S    V  S+       +  P   G  S G      G   +SS  G G  G    
Sbjct: 203 GSSGGSGSGYVS-SQQVTQTSCAPQPSYGGGSSGGG--GSGGSGCFSSGGGGGSSGCGGG 259

Query: 418 ELGVGASGLNEFGETGLSGSEKG 440
             G+G+  +   G +   G   G
Sbjct: 260 SSGIGSGCIISGGGSVCGGGSSG 282



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 50/169 (29%), Positives = 55/169 (32%), Gaps = 37/169 (21%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG G  GS     GF G G     S      +  G G + GG        G   SG  G 
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGC-------GGGSSGGGGG 74

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
                 G G G S   +G   SSG                      GG+   SS    +G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSG----------------------GGSGCFSSGGGGSG 112

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S G   S  GG   S    SGGGG S      G SG    G  G SG
Sbjct: 113 CFSSGGGGSSGGG---SGCFSSGGGGSSG-----GGSGCFSSGGGGFSG 153



>gi|56204896|emb|CAI19560.1|   loricrin [Homo sapiens]
          Length = 312

 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 81/283 (28%), Positives = 96/283 (33%), Gaps = 24/283 (8%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G G  G   G G G  + G   S     G  G S     G  +   GG      G  S  
Sbjct: 30  GGGGCGFFGGGGSGGGSSG---SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS-----VSAEAGFKGFGSDSSSS 292
           S     GGGS    S  + SG  G G    GG G SG       S   G  G GS   SS
Sbjct: 87  SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSS 146

Query: 293 VEKSWLFEFGLGETKGGAEFNFRDSGSN---QSGDNGNSSKDFDGNGVGDSSARNGFENS 349
               +  +    ++ GG        G +    SG  G S   + G G G     +G   S
Sbjct: 147 GGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGS 206

Query: 350 SGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGS 409
             +S         + Q       +GG     S     G  S G     SG    SS  GS
Sbjct: 207 GYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGS-----GCFSSGGGGGSSGCGGGSSGIGS 261

Query: 410 G----GGGKSADELGVGASGLNEFGET-GLSGSEKGSHIPEAT 447
           G    GGG      G G+SG    G + G SGS KG  I   T
Sbjct: 262 GCIISGGGSVC---GGGSSGGGGGGSSVGGSGSGKGVPICHQT 301



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 50/169 (29%), Positives = 55/169 (32%), Gaps = 37/169 (21%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG G  GS     GF G G     S      +  G G + GG        G   SG  G 
Sbjct: 22  GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGC-------GGGSSGGGGG 74

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
                 G G G S   +G   SSG                      GG+   SS    +G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSG----------------------GGSGCFSSGGGGSG 112

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S G   S  GG   S    SGGGG S      G SG    G  G SG
Sbjct: 113 CFSSGGGGSSGGG---SGCFSSGGGGSSG-----GGSGCFSSGGGGFSG 153



>gi|55961914|emb|CAI17705.1|   chromosome 6 open reading frame 205 [Homo sapiens]
 gi|58219026|ref|NP_001010909.1|   chromosome 6 open reading frame 205 [Homo sapiens]
          Length = 566

 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 82/371 (22%), Positives = 146/371 (39%), Gaps = 31/371 (8%)

Query: 83  SSSSGDSDRTKPFFSL---GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDS 139
           ++SSG S  T   FS    G+     +E  +  S  +  + SE + P     G+S++ +S
Sbjct: 82  TTSSGISTATNSEFSTASSGISIATNSESSTTSSGASTATNSESSTPSS---GASTATNS 138

Query: 140 DKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEV 199
           D           +T      +    D+  + SE S A  + SS    GA     +    V
Sbjct: 139 DS----------STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTV 188

Query: 200 SDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG-DTSFRSENQFVGGGSLNSISNLWDSG 258
           S   S      SS T  G  T+++  S +   G  T+  SE+     G+  + ++   + 
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248

Query: 259 QEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSG 318
             G G      N  S + S+ AG     ++S SS   S +       T   +E +   SG
Sbjct: 249 SSGAGT---ATNSESSTTSSGAGT---ATNSESSTVSSGI------STVTNSESSTPSSG 296

Query: 319 SNQSGDNGNSSKDFDGNGV--GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
           +N + ++ +S+     N     DSS  +   +++  SE S    G+S     E S T   
Sbjct: 297 ANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSG 356

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
              +++   +   S  S  ++S  +T SS + +    +S+      ++  N    T  SG
Sbjct: 357 ASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSG 416

Query: 437 SEKGSHIPEAT 447
           +   ++   +T
Sbjct: 417 ASTATNSESST 427



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 162/426 (38%), Gaps = 63/426 (14%)

Query: 24  SRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSS 83
           S S   S G+S++ + +   P       S     D S     A +  + D+       S+
Sbjct: 108 SESSTTSSGASTATNSESSTPSSG---ASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164

Query: 84  SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
           +++ +S  T    S G      +E  +  S+ +  + SE +       G+S++ +S+ + 
Sbjct: 165 ATNSESSTT----SSGASTATNSESSTVSSRASTATNSESSTTSS---GASTATNSESRT 217

Query: 144 PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                      E    S     A NS S  +P+ G G++     +     A G   +  +
Sbjct: 218 TSNGAGTATNSESSTTSSGASTATNSESS-TPSSGAGTATNSESSTTSSGA-GTATNSES 275

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFG 263
           S   +GIS+ T   + T SSG        +T+  SE+     G+ N+ +N          
Sbjct: 276 STVSSGISTVTNSESSTPSSG-------ANTATNSESSTTSSGA-NTATN---------S 318

Query: 264 INEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            +    +G S + ++E+     G+ ++++ E S         T  GA      S +  SG
Sbjct: 319 DSSTTSSGASTATNSESSTTSSGASTATNSESS--------TTSSGA------STATNSG 364

Query: 324 DNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDP 383
            +  SS        G S+A N        SE S V  G+S     E S T      +++ 
Sbjct: 365 SSTTSS--------GTSTATN--------SESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 384 DEAGNLSPGSDVSDSGGNTWSSDSGSG-GGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           + +   S  S  ++S  +T SS + +    G S    G G + L     T  S S   + 
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAS---TA 465

Query: 443 IPEATP 448
           + EA P
Sbjct: 466 VSEAKP 471



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 53/283 (18%), Positives = 113/283 (39%), Gaps = 39/283 (13%)

Query: 165 DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
           +A  + +E S +  TGSS +  GA           +  +S   +G+S+ T+ G+  +S+G
Sbjct: 19  EAATNSNETSTSANTGSSVISSGASTA-------TNSGSSVTSSGVSTATISGSSVTSNG 71

Query: 225 GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
            S+   + ++ F + +  +   + +  S                 +G+S + ++E+    
Sbjct: 72  VSI---VTNSEFHTTSSGISTATNSEFST--------------ASSGISIATNSESSTTS 114

Query: 285 FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARN 344
            G+ ++++ E S         + G +     DS +  SG +  ++ D        S+A N
Sbjct: 115 SGASTATNSESST-------PSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATN 167

Query: 345 GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWS 404
                   SE S    G+S     E S        +++ + +   S  S  ++S   T S
Sbjct: 168 --------SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTS 219

Query: 405 SDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEAT 447
           + +G+    +S+      ++  N    T  SG+   ++   +T
Sbjct: 220 NGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262



>gi|55961891|emb|CAI18008.1|   chromosome 6 open reading frame 205 [Homo sapiens]
          Length = 566

 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 82/371 (22%), Positives = 146/371 (39%), Gaps = 31/371 (8%)

Query: 83  SSSSGDSDRTKPFFSL---GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDS 139
           ++SSG S  T   FS    G+     +E  +  S  +  + SE + P     G+S++ +S
Sbjct: 82  TTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSS---GASTATNS 138

Query: 140 DKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEV 199
           D           +T      +    D+  + SE S A  + SS    GA     +    V
Sbjct: 139 DS----------STTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTV 188

Query: 200 SDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG-DTSFRSENQFVGGGSLNSISNLWDSG 258
           S   S      SS T  G  T+++  S +   G  T+  SE+     G+  + ++   + 
Sbjct: 189 SSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTP 248

Query: 259 QEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSG 318
             G G      N  S + S+ AG     ++S SS   S +       T   +E +   SG
Sbjct: 249 SSGAGT---ATNSESSTTSSGAGT---ATNSESSTVSSGI------STVTNSESSTPSSG 296

Query: 319 SNQSGDNGNSSKDFDGNGV--GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
           +N + ++ +S+     N     DSS  +   +++  SE S    G+S     E S T   
Sbjct: 297 ANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSG 356

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
              +++   +   S  S  ++S  +T SS + +    +S+      ++  N    T  SG
Sbjct: 357 ASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSG 416

Query: 437 SEKGSHIPEAT 447
           +   ++   +T
Sbjct: 417 ASTATNSESST 427



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 93/426 (21%), Positives = 162/426 (38%), Gaps = 63/426 (14%)

Query: 24  SRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSS 83
           S S   S G+S++ + +   P       S     D S     A +  + D+       S+
Sbjct: 108 SESSTTSSGASTATNSESSTPSSG---ASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164

Query: 84  SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
           +++ +S  T    S G      +E  +  S+ +  + SE +       G+S++ +S+ + 
Sbjct: 165 ATNSESSTT----SSGASTATNSESSTVSSRASTATNSESSTTSS---GASTATNSESRT 217

Query: 144 PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
                      E    S     A NS S  +P+ G G++     +     A G   +  +
Sbjct: 218 TSNGAGTATNSESSTTSSGASTATNSESS-TPSSGAGTATNSESSTTSSGA-GTATNSES 275

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFG 263
           S   +GIS+ T   + T SSG        +T+  SE+     G+ N+ +N          
Sbjct: 276 STVSSGISTVTNSESSTPSSG-------ANTATNSESSTTSSGA-NTATN---------S 318

Query: 264 INEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            +    +G S + ++E+     G+ ++++ E S         T  GA      S +  SG
Sbjct: 319 DSSTTSSGASTATNSESSTTSSGASTATNSESS--------TTSSGA------STATNSG 364

Query: 324 DNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDP 383
            +  SS        G S+A N        SE S V  G+S     E S T      +++ 
Sbjct: 365 SSTTSS--------GTSTATN--------SESSTVSSGASTATTSESSTTSSGASTATNS 408

Query: 384 DEAGNLSPGSDVSDSGGNTWSSDSGSG-GGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           + +   S  S  ++S  +T SS + +    G S    G G + L     T  S S   + 
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSAS---TA 465

Query: 443 IPEATP 448
           + EA P
Sbjct: 466 VSEAKP 471



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 53/283 (18%), Positives = 114/283 (40%), Gaps = 39/283 (13%)

Query: 165 DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
           +A  + +E S +  TGSS +  GA           +  +S   +G+S+ T+ G+  +S+G
Sbjct: 19  EAATNSNETSTSANTGSSVISSGASTA-------TNSGSSVTSSGVSTATISGSSVTSNG 71

Query: 225 GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
            S+   + ++ F + +  +   + +  S +               +G+S + ++E+    
Sbjct: 72  VSI---VTNSEFHTTSSGISTATNSEFSTV--------------SSGISIATNSESSTTS 114

Query: 285 FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARN 344
            G+ ++++ E S         + G +     DS +  SG +  ++ D        S+A N
Sbjct: 115 SGASTATNSESST-------PSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATN 167

Query: 345 GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWS 404
                   SE S    G+S     E S        +++ + +   S  S  ++S   T S
Sbjct: 168 --------SESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTS 219

Query: 405 SDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEAT 447
           + +G+    +S+      ++  N    T  SG+   ++   +T
Sbjct: 220 NGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESST 262



>gi|21748896|dbj|BAC03505.1|   unnamed protein product [Homo sapiens]
          Length = 294

 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 33/101 (32%), Positives = 49/101 (48%), Gaps = 1/101 (0%)

Query: 910  VLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNW 969
            +LQDG VT V         L      +   G  +IL  Q G+ V+WD  +++ V +  ++
Sbjct: 107  LLQDGAVT-VDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSY 165

Query: 970  NGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQ 1010
             G+ CGLCGN NG  +DD       +      FGNSW+  +
Sbjct: 166  QGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVQE 206



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 19/49 (38%), Positives = 30/49 (61%)

Query: 633 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM 681
           Q+ VS+P +    T GLCG++N  A+DD    + +L  +  AF NSW++
Sbjct: 156 QVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQV 204



>gi|56205087|emb|CAI19595.1|   filaggrin [Homo sapiens]
 gi|60097902|ref|NP_002007.1|   filaggrin [Homo sapiens]
          Length = 4061

 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 97/405 (23%), Positives = 152/405 (37%), Gaps = 45/405 (11%)

Query: 59  KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG 118
           +SR R+  GS  S+D       +S   S DS+R     S      G A ++S D      
Sbjct: 286 ESRTRKRRGSRVSQDR------DSEGHSEDSERHSG--SASRNHHGSAWEQSRDGSRHPR 337

Query: 119 SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSR----ERWDAGNSRSEDS 174
           S  ED    G  + + SS  S  +    S   G T    +++R    ER  +G+ +S DS
Sbjct: 338 SHDEDRASHG--HSADSSRQSGTRHAETSSR-GQTASSHEQARSSPGERHGSGHQQSADS 394

Query: 175 P---AVGTGSSGLKL---------GAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSS 222
               A G G +   +         G+   D+    E SD+ S    G +    + +Q S+
Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQEST 454

Query: 223 SGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF 282
            G S     G+ S RS      G SL  +S   +      G       G  GS   +A  
Sbjct: 455 RGRS-----GERSGRS------GSSLYQVST-HEQPDSAHGRTGTSTGGRQGSHHEQARD 502

Query: 283 KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSA 342
               S  S+S E         G ++GG + +  +   N+SG +G+        G  D+S 
Sbjct: 503 S---SRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASH 559

Query: 343 RNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGN 401
                 S+     +    G   +H         ++  SS   + G   S G   S + G+
Sbjct: 560 GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGS 619

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
           + S DS S G  + ++    G++  N  G +    S  GS  P +
Sbjct: 620 SVSQDSDSQGHSEDSERWS-GSASRNHHG-SAQEQSRDGSRHPRS 662



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 92/407 (22%), Positives = 151/407 (37%), Gaps = 56/407 (13%)

Query: 52   SPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSG 111
            S G + + SRQ       +  +T +GG    ++SS +  R+ P    G     + +  + 
Sbjct: 1642 SHGHSAESSRQ----SGTRHAETSSGG---QAASSQEQARSSP----GERHGSRHQQSAD 1690

Query: 112  DSQDAGGSKSEDTPPGGFF--YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
             S D+G  + +D+   G     GSS S  SD +        G + E + +S         
Sbjct: 1691 SSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSE--------GHSEESDTQSVSAHGQAGP 1742

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG---S 226
              +       G SG + G      +F ++VS       T   S++  G    S+GG   S
Sbjct: 1743 HQQSHQESTRGQSGERSGRS---GSFLYQVS-------THEQSESAHGRTGPSTGGRQRS 1792

Query: 227  VSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE-IGGNGMSGS-----VSAEA 280
                  D+S  S +Q  G  ++         G++G    + +  +G SGS      S E 
Sbjct: 1793 RHEQARDSSRHSASQ-EGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQER 1851

Query: 281  GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
                 G   S SV +    E   G+  G      R   ++   D+   S+   G   G  
Sbjct: 1852 SDVSRGQSGSRSVSRQTRNEKQSGD--GSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909

Query: 341  SARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSS-----DPDEAGNLSPGSDV 395
            ++RN     S +S+DS      S  H  +  R  G+  R+      +    G+  PGS  
Sbjct: 1910 TSRN---QGSSVSQDS-----DSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHH 1961

Query: 396  SDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
             D  G+  S+DS    G +  +    G +  +       +G   GSH
Sbjct: 1962 EDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSH 2008



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 94/423 (22%), Positives = 144/423 (34%), Gaps = 32/423 (7%)

Query: 17   KDGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPA 76
            + G  +ASR    +Y    SGD  R       E  S  ++   S   Q   S      P 
Sbjct: 2183 QSGSRSASRK---TYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPR 2239

Query: 77   GGFFNSSSSSG----DSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYG 132
            G   +  S S     DS+R     S      G A+++S D      S  ED        G
Sbjct: 2240 GSSVSQDSDSEGHSEDSERRSG--SASRNHHGSAQEQSRDGSRHPRSHHEDRA------G 2291

Query: 133  SSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGD 192
               S +S ++      E  ++G     S E+  +       S    +  S    G G G 
Sbjct: 2292 HGHSAESSRQSGTHHAE-NSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQ 2350

Query: 193  AAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID----------LGDTSFRSENQF 242
            A+    V DS   G +G  +   EG+   S   SVS               T  RS  + 
Sbjct: 2351 ASSA--VRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408

Query: 243  VGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFG 302
               GS     +  +  +   G       G  GS   +A      S  S+S E        
Sbjct: 2409 GRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDS---SRHSTSQEGQDTIHGH 2465

Query: 303  LGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGS 362
             G + GG + +  +   ++SG +G+        G  D+S  +    S+     +    G 
Sbjct: 2466 PGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525

Query: 363  SDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGV 421
              +H         +R  SS   + G   S G   S + G+++S DS S G  + ++    
Sbjct: 2526 GSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG 2585

Query: 422  GAS 424
             AS
Sbjct: 2586 SAS 2588



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 51/438 (11%)

Query: 26   SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
            SG   + +SS  D  R   +   +   P       R  ++ GS  S+D+      +S   
Sbjct: 1881 SGSRHHEASSRADSSRHSQVGQGQSSGP-------RTSRNQGSSVSQDS------DSQGH 1927

Query: 86   SGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPL 145
            S DS+R     S      G A ++S D     GS  ED        G   S DS ++   
Sbjct: 1928 SEDSERWSG--SASRNHLGSAWEQSRDGSRHPGSHHEDRA------GHGHSADSSRQSGT 1979

Query: 146  FSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSF 205
               E  + G+      +   +   R      + +  S    G G G A+    V DS   
Sbjct: 1980 RHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSA--VRDSGHR 2037

Query: 206  GDTGISSKTVEGNQTSSSGGSVSID-LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGI 264
            G +G  +   EG+   S   SVS         +S  +   G S  S      SG+ G  +
Sbjct: 2038 GYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES------SGRSGSFL 2091

Query: 265  NEIGGNGMSGSVSAEA-----GFKGFGSDSSSSVEKSWLFEFGL-------GETKGGAEF 312
             ++  +  S S   ++     G +G   D +    +    + G        G ++GG + 
Sbjct: 2092 YQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQG 2151

Query: 313  NFRDSGSNQSGDNGNSSKDFDGNGVGDSS-ARNGFENSSGIS---EDSGVILGSSDQHEV 368
            + ++   ++SG +G+        G  D+S  ++G  ++S  +   E SG     S  H  
Sbjct: 2152 SHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHH 2211

Query: 369  ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNE 428
            E S    + + S         S G   S   G++ S DS S G  + ++    G++  N 
Sbjct: 2212 EASSWADSSRHSL---VGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRS-GSASRNH 2267

Query: 429  FGETGLSGSEKGSHIPEA 446
             G +    S  GS  P +
Sbjct: 2268 HG-SAQEQSRDGSRHPRS 2284



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 81/408 (19%), Positives = 136/408 (33%), Gaps = 34/408 (8%)

Query: 26   SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
            SG   + +S+  D+ R            G++E   R R+   S   +    G   +S   
Sbjct: 2854 SGSRHHEASTHADISRHSQAVQ------GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907

Query: 86   SGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPL 145
            SG + R            G A+++  D      S  ED        G   S DS ++   
Sbjct: 2908 SGSASRNHH---------GSAQEQLRDGSRHPRSHQEDRA------GHGHSADSSRQSGT 2952

Query: 146  FSFEFGATGEDEDKSRE-RWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNS 204
               +  + G+      + R  AG             S    +G G+  +A    V DS  
Sbjct: 2953 RHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA----VRDSGH 3008

Query: 205  FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGI 264
             G +G  +   EG+   S   SVS      S +  +Q    G     S    S       
Sbjct: 3009 RGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVST 3068

Query: 265  NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL-------GETKGGAEFNFRDS 317
            +E   +    +  +  G +G   + +    +    ++G        G ++GG +    + 
Sbjct: 3069 HEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEH 3128

Query: 318  GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
              + SG +G+        G  D+S       S+  +  +    G S +H V         
Sbjct: 3129 SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTH 3188

Query: 378  KRSSDPDEA-GNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
               S   +A    S GS  S   G++ S DS S G  + ++     AS
Sbjct: 3189 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSAS 3236



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 99/461 (21%), Positives = 159/461 (34%), Gaps = 43/461 (9%)

Query: 26   SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
            SG   + +SS  D  R   +   +   P       R  ++ GS  S+D+      +S   
Sbjct: 584  SGSRHHEASSQADSSRHSQVGQGQSSGP-------RTSRNQGSSVSQDS------DSQGH 630

Query: 86   SGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPL 145
            S DS+R     S      G A+++S D      S  ED        G   S DS +K   
Sbjct: 631  SEDSERWSG--SASRNHHGSAQEQSRDGSRHPRSHHEDRA------GHGHSADSSRKSGT 682

Query: 146  FSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSF 205
               +  ++G+      +   +   R      + +  S    G G G A+    V DS   
Sbjct: 683  RHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSA--VRDSGHR 740

Query: 206  GDTGISSKTVEGNQTSSSGGSVSIDLGDTSF------RSENQFVGGGSLNSISNLWDSGQ 259
            G +G  +   EG+   S   SVS   G           S     G  S  S S L+    
Sbjct: 741  GSSGSQATDSEGHSEDSDTQSVS-GHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVST 799

Query: 260  EGFGINEIGGNGMSGSVSAEAGFKGFGSDS--SSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                 +  G  G S  V   +  +    +S  S+S +         G ++ G + +  + 
Sbjct: 800  HKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQ 859

Query: 318  GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
              ++SG +G+        G  D+S       S+  +  +        +H         + 
Sbjct: 860  SVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSH 919

Query: 378  KRSSDPDEAG-NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
               S   +AG   S GS  S   G++ S DS S G  + ++    G++  N  G    S 
Sbjct: 920  ADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWS-GSASRNHRG----SA 974

Query: 437  SEKGSHIPEATPKYSETNAIIGQDINEHIANSKIPGDCPNA 477
             E+  H       + E  A  G     H A+S      P+A
Sbjct: 975  QEQSRHGSRHPRSHHEDRAGHG-----HSADSSRQSGTPHA 1010



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 121/508 (23%), Positives = 181/508 (35%), Gaps = 69/508 (13%)

Query: 32   GSSSSGDLDRKKPLFSLE--FGSPGETEDKSRQRQDAGS---PKSEDTPAGGFFNSSSSS 86
            GSS S D D +      E   GS       S Q Q       P S      G  +S+ SS
Sbjct: 3536 GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESS 3595

Query: 87   GDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS----KSEDTPPGGFFYGSSSSG--DSD 140
              S       S G  A    E     + +  GS     ++ +   G  +G +SS   DS 
Sbjct: 3596 RQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3655

Query: 141  KKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVS 200
             +    S    + G  ED   +   A         +    + G   G      +F ++VS
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 3715

Query: 201  ----DSNSFGDTGISSKTVEGNQ----TSSSGGSVSIDLGDTSFRSENQFVGG--GSLN- 249
                  ++ G  G S+   +G++      SS  S S +  DT         GG  GS + 
Sbjct: 3716 THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHE 3775

Query: 250  -SISNLWDSGQEGFGINEIG----GNGMSGSVSAEA----------GFKGFGS---DSSS 291
             S+     SG         G     +G SGS SA            G +  GS   ++S+
Sbjct: 3776 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEAST 3835

Query: 292  SVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
              + S   + G GE+ G      R  GS+ S D+ + +   D     +S++RN   +S  
Sbjct: 3836 QADSSRHSQSGQGESAGSRRS--RRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSRE 3893

Query: 352  ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
             S D     GSS +      ++   +  SS   E G+ S  S   DS  ++     GS  
Sbjct: 3894 QSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLS--QDSAYHSGIQSRGSPH 3951

Query: 412  GGKS------ADELGVGASGL-----------NEFGETGLSGSEKGSHIPEATP-KYSET 453
               S        E   G SGL            ++GE+G   S+ GS    + P  + E 
Sbjct: 3952 SSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSVSYNSNPVVFKER 4011

Query: 454  NAI-----IGQDINEHIAN--SKIPGDC 474
            + I      G+D   + A   +K PG C
Sbjct: 4012 SDICKASAFGKDHPRYYATYINKDPGLC 4039



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 87/403 (21%), Positives = 138/403 (34%), Gaps = 33/403 (8%)

Query: 55   ETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQ 114
            E    SR  +  GS  S+D+      +S   S DS+R     S      G + ++S D  
Sbjct: 1255 EQSSGSRTSRHQGSSVSQDS------DSERHSDDSERLSG--SASRNHHGSSREQSRDGS 1306

Query: 115  DAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDS 174
               G   ED    G       S DS ++      E  + G+      +   A +S  E  
Sbjct: 1307 RHPGFHQEDRASHGH------SADSSRQSGTHHTESSSHGQAVSSHEQ---ARSSPGERH 1357

Query: 175  PAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI----- 229
             +    S+     +G G       V DS   G +G      EG+   S   SVS      
Sbjct: 1358 GSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAG 1417

Query: 230  ---DLGDTSFRSENQFVGGGSLNSISNL--WDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
                    S R ++    G S + +  +   +  +   G       G  GS   +A    
Sbjct: 1418 PHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNS- 1476

Query: 285  FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARN 344
              S  S+S +         G ++GG + ++ +   ++SG +G         G  D+S   
Sbjct: 1477 --SRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQ 1534

Query: 345  GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTW 403
                S+     +    G   +H          R  SS   + G   S GS  S   G++ 
Sbjct: 1535 SGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSV 1594

Query: 404  SSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
            S D  S G  + ++     AS  N +G +    S  GS  P +
Sbjct: 1595 SQDRDSEGHSEDSERRSESAS-RNHYG-SAREQSRHGSRNPRS 1635



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 92/432 (21%), Positives = 148/432 (34%), Gaps = 55/432 (12%)

Query: 26   SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
            SG   + +SS  D+ R            G++E     R+   S   +    G   +S   
Sbjct: 909  SGSRHHEASSHADISRHSQ------AGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERW 962

Query: 86   SGDSDRTKPFFSLGLGAPGKA------EDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDS 139
            SG + R     +      G        ED++G    A  S+   TP      G  ++   
Sbjct: 963  SGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSH 1022

Query: 140  DKKKPLFSFEFGATGEDE-DKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFE 198
            ++ +       G+  +   D SR    +G  R + S AV         G+   D+    E
Sbjct: 1023 EQARSSPGERHGSRHQQSADSSRH---SGIPRRQASSAVRDSGHWGSSGSQASDSEGHSE 1079

Query: 199  VSDSNSFGDTGISSKTVEGNQTSS-------SGGSVSIDLGDTSFRSENQFVGGGSLNSI 251
             SD+ S    G      + +Q S+       SG S S  +   S   +++   G +  S 
Sbjct: 1080 ESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSF-IYQVSTHEQSESAHGRTRTST 1138

Query: 252  SNLWDSGQEGFGINEIGGNGMSG--SVSAEAGFKGFGSDSS---SSVEKSWLFEFGLGET 306
                 S  E    +        G  ++ A  G +  G   S    SV++S         T
Sbjct: 1139 GRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHT 1198

Query: 307  --KGGAEFNFRDSGSN----------QSGDNG--NSSKDFDGNGVGDSSARN--GFENSS 350
              +G ++ +   SGS           QSGD    + S+  +     DSS  +  G E SS
Sbjct: 1199 TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSS 1258

Query: 351  G----------ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGG 400
            G          +S+DS     S D   +  S +  +   S +    G+  PG    D   
Sbjct: 1259 GSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRAS 1318

Query: 401  NTWSSDSGSGGG 412
            +  S+DS    G
Sbjct: 1319 HGHSADSSRQSG 1330



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 81/385 (21%), Positives = 132/385 (34%), Gaps = 38/385 (9%)

Query: 54   GETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDS 113
            G++E   R R+   S   +    G   +S   SG + R            G    +S   
Sbjct: 3200 GQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHE 3259

Query: 114  QDAGGSKSED-TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSR--ERWDAGNSR 170
              AG   S D +   G  +  +SSG              A+  ++ +S   ER  + + +
Sbjct: 3260 DRAGHGHSADRSRQSGTRHAETSSGGQ-----------AASSHEQARSSPGERHGSRHQQ 3308

Query: 171  SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVS-- 228
            S DS    +  SG+  G           V DS  +G +G  +   EG+   S   SVS  
Sbjct: 3309 SADS----SRHSGIPRGQASS------AVRDSRHWGSSGSQASDSEGHSEESDTQSVSGH 3358

Query: 229  ---IDLGDTSFRSENQFVGGGSLNSISNLW-----DSGQEGFGINEIGGNGMSGSVSAEA 280
                    +   S     GG S  S S L+     +  +   G          GS   +A
Sbjct: 3359 GQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQA 3418

Query: 281  GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
                  S  S+S E         G ++ G + +  +   ++SG +G+        G  D+
Sbjct: 3419 ---RDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDA 3475

Query: 341  SARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSG 399
            S       S+     +    G   +H          +  SS   ++G   S G   S + 
Sbjct: 3476 SRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQ 3535

Query: 400  GNTWSSDSGSGGGGKSADELGVGAS 424
            G++ S DS S G  + ++     AS
Sbjct: 3536 GSSVSQDSDSQGHSEDSERWSGSAS 3560



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 87/422 (20%), Positives = 140/422 (33%), Gaps = 34/422 (8%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQ-DAGSPKSEDTPAG 77
            G  +ASR    +     SGD  R       E  S  ++   S+  Q  +  P++      
Sbjct: 2509 GSRSASRQ---TRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGS 2565

Query: 78   GFFNSSSSSGDSDRTKPFF-SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
             F   S S G S+ ++ +  S      G A+++  D      S  ED        G   S
Sbjct: 2566 SFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA------GHGHS 2619

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSRE-RWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAF 195
             DS ++      +  + G+      + R  AG             S    +G G+  +A 
Sbjct: 2620 ADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSA- 2678

Query: 196  GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLW 255
               V DS   G +G  +   EG+   S   SVS      S +  +Q    G     S   
Sbjct: 2679 ---VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETS--- 2732

Query: 256  DSGQEGFGINEIGGNGMSGSVSAEAGFKGFG------------SDSSSSVEKSWLFEFGL 303
              G  G  + ++  +  S S     G    G            S  S+S +         
Sbjct: 2733 --GHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHP 2790

Query: 304  GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSS 363
            G ++GG +    +   + SG +G+        G  D+S       S+  +  +    G  
Sbjct: 2791 GSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG 2850

Query: 364  DQHEVELSRTGGNRKRSSDPDEA-GNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVG 422
             +H              S   +A    S GS  S   G++ S DS S G  + ++     
Sbjct: 2851 SRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGS 2910

Query: 423  AS 424
            AS
Sbjct: 2911 AS 2912



>gi|190394|gb|AAA63243.1|   profilaggrin
          Length = 1084

 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 93/421 (22%), Positives = 153/421 (36%), Gaps = 30/421 (7%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQ-DAGSPKSEDTPAG 77
           G  +ASR    ++    SGD  R       E  S  ++   S+  Q ++   ++      
Sbjct: 178 GSRSASRE---THNEEQSGDGSRHSGSRHQEASSWADSSGHSQAGQGESSGSRTSRNQGS 234

Query: 78  GFFNSSSSSGDS-DRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
            F   S S G S D  +   S      G A ++S D     GS  ED    G    SS  
Sbjct: 235 SFSQDSDSQGQSEDSERRSGSASRNHRGSAREQSRDGSRHPGSHHEDRAGHGHSADSSXQ 294

Query: 137 GDSDKKKPLFSFEFGATGEDEDKSR--ERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
             + +     S    A+ +++ +SR  +R  +G+ +S DS            G G+G A+
Sbjct: 295 SGT-RHTQTSSRRQAASSQEQARSRAGDRHGSGHQQSADSSRHS--------GIGRGQAS 345

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVS--------IDLGDTSFRSENQFVGG- 245
               V DS   G  G  +   EG+   S   SV+         +    S R +++   G 
Sbjct: 346 TA--VRDSGHRGSRGSQASDNEGHSEDSDTQSVAGQRQAGSHHESHQESTRGQSRETSGR 403

Query: 246 -GSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLG 304
            GS     +  +  +   G +     G  GS   +A      S S    +       G G
Sbjct: 404 SGSFLYQVSTHEQSESSHGWSGTSTRGRQGSHHEQAQDSSRHSASQEGQDTIHGHP-GPG 462

Query: 305 ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSD 364
            ++GG   +  +   ++SG +G+        G  D+S  +    S+     +    G   
Sbjct: 463 SSRGGRHGSHYEQSVDRSGHSGSHHSHTTSQGRSDASHGSSGSRSASRQTRNEEQSGDGS 522

Query: 365 QHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGA 423
           +H          +  SS   +AG   S G   S + G++ S DS S G  + ++     A
Sbjct: 523 RHSRSHHHEASTQADSSRHSQAGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSA 582

Query: 424 S 424
           S
Sbjct: 583 S 583



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 108/460 (23%), Positives = 166/460 (36%), Gaps = 67/460 (14%)

Query: 58   DKSRQRQDAGSPKSEDTPAGGFFNSS-SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA 116
            + S   Q A S +   + AG    S    S DS R       G+G  G+A     DS   
Sbjct: 627  ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-----GIGH-GQASSAVRDSGHR 680

Query: 117  GGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKS-RERWDAGNSRS---- 171
            G S S+ +   G       S DSD +      + G+  +   +S R R   G+ RS    
Sbjct: 681  GSSGSQASDSEGH------SEDSDTQSVSAHGQAGSHQQSHQESTRGRSQEGSGRSGSFL 734

Query: 172  -----EDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGS 226
                  +      G +G   G  +G        S  +S    G    T+ G+  S  GG 
Sbjct: 735  YQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG--QDTIRGHPGSRRGGR 792

Query: 227  VSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA----GF 282
                    S+  ++    G S +  S+    G+      + G    S     E     G 
Sbjct: 793  QG------SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS 846

Query: 283  KGFGS---DSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGD 339
            +  GS   ++S+  + S   + G GE+ G      R  GS+ S D+ + +   D     +
Sbjct: 847  RHSGSRHHEASTQADSSRHSQSGQGESAGSRRS--RRQGSSVSQDSDSEAYPEDSERRSE 904

Query: 340  SSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG 399
            S++RN   +S   S D     GSS +      ++   +  SS   E G+ S  S   DS 
Sbjct: 905  SASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLS--QDSA 962

Query: 400  GNTWSSDSGSGGGGKS------ADELGVGASGL-----------NEFGETGLSGSEKGSH 442
             ++     GS     S        E   G SGL            ++GE+G   S+ GS 
Sbjct: 963  YHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSV 1022

Query: 443  IPEATP-KYSETNAI-----IGQDINEHIAN--SKIPGDC 474
               + P  + E + I      G+D   + A   +K PG C
Sbjct: 1023 SYNSNPVLFKERSDICKASAFGKDHPRYYATYINKDPGLC 1062



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 64/271 (23%), Positives = 96/271 (35%), Gaps = 21/271 (7%)

Query: 187 GAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID----------LGDTSF 236
           G G G A+    V DS   G +G  +   EG+   S   SVS               T  
Sbjct: 14  GIGHGQASSA--VRDSGHRGSSGSQASDSEGHSEDSDTQSVSAQGQAGPHQQSHQESTRG 71

Query: 237 RSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
           RS  +    GS     +  +  +   G       G  GS   +A      S  S+S E  
Sbjct: 72  RSAGRSGRSGSFLYQVSTHEQSESAHGRARTSTRGRQGSHHEQA---RDSSRHSTSQEGQ 128

Query: 297 WLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDS 356
                  G + GG   +  +   N +G +G+        G  D+S       S+     +
Sbjct: 129 DTIRGHPGPSSGGRHGSHYEQSVNSTGHSGSHHSHTTSQGRSDASHGTSGSRSASRETHN 188

Query: 357 GVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTWSSDSGSGGGGKS 415
               G   +H     +   +   SS   +AG   S GS  S + G+++S DS S G  + 
Sbjct: 189 EEQSGDGSRHSGSRHQEASSWADSSGHSQAGQGESSGSRTSRNQGSSFSQDSDSQGQSED 248

Query: 416 ADELGVGASGLNEFG---ETGLSGS-EKGSH 442
           ++    G++  N  G   E    GS   GSH
Sbjct: 249 SERRS-GSASRNHRGSAREQSRDGSRHPGSH 278



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 24/296 (8%)

Query: 128 GFFYGSSSSG--DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLK 185
           G  +G +SS   DS  +    S    + G  ED   +   A         +    + G  
Sbjct: 14  GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAQGQAGPHQQSHQESTRGRS 73

Query: 186 LGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGN-QTSSSG--GSVSIDLGDTSFRSENQF 242
            G      +F ++VS       T   S++  G  +TS+ G  GS      D+S  S +Q 
Sbjct: 74  AGRSGRSGSFLYQVS-------THEQSESAHGRARTSTRGRQGSHHEQARDSSRHSTSQ- 125

Query: 243 VGGGSLNSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKG-----FGSDSSSSVEKS 296
            G  ++         G+ G    + +   G SGS  +    +G      G+  S S  + 
Sbjct: 126 EGQDTIRGHPGPSSGGRHGSHYEQSVNSTGHSGSHHSHTTSQGRSDASHGTSGSRSASRE 185

Query: 297 WLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDS 356
              E   G+  G      R   ++   D+   S+   G   G  ++RN     S  S+DS
Sbjct: 186 THNEEQSGD--GSRHSGSRHQEASSWADSSGHSQAGQGESSGSRTSRN---QGSSFSQDS 240

Query: 357 GVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGG 412
                S D      S +  +R  + +    G+  PGS   D  G+  S+DS    G
Sbjct: 241 DSQGQSEDSERRSGSASRNHRGSAREQSRDGSRHPGSHHEDRAGHGHSADSSXQSG 296



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 85/394 (21%), Positives = 132/394 (33%), Gaps = 33/394 (8%)

Query: 32  GSSSSGDLDRKKPLFSLE--FGSPGETEDKSRQRQDAGS---PKSEDTPAGGFFNSSSSS 86
           GSS S D D +      E   GS       S Q Q       P S      G  +S+ SS
Sbjct: 559 GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHRHSAESS 618

Query: 87  GDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS----KSEDTPPGGFFYGSSSSG--DSD 140
             S       S G  A    E     + +  GS     ++ +   G  +G +SS   DS 
Sbjct: 619 DQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 678

Query: 141 KKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVS 200
            +    S    + G  ED   +   A         +    + G          +F ++VS
Sbjct: 679 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGSHQQSHQESTRGRSQEGSGRSGSFLYQVS 738

Query: 201 DSNSFGDTGISSKTVEGNQTSSSGG---SVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
                  T   S++  G    S+GG   S      D+S  S +Q  G  ++         
Sbjct: 739 -------THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQ-EGQDTIRGHPGSRRG 790

Query: 258 GQEG-FGINEIGGNGMSGSVSAEAGFKG-----FGSDSSSSVEKSWLFEFGLGETKGGAE 311
           G++G +    +  +G SGS  +    +G      G   S S  +    E   G+  G   
Sbjct: 791 GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD--GSRH 848

Query: 312 FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELS 371
              R   ++   D+   S+   G   G   +R      S +S+DS       D      S
Sbjct: 849 SGSRHHEASTQADSSRHSQSGQGESAGSRRSRR---QGSSVSQDSDSEAYPEDSERRSES 905

Query: 372 RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
            +  +   S +    G+  PGS   D+  +  SS
Sbjct: 906 ASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSS 939



>gi|3334747|emb|CAA04738.1|   MUC5AC protein [Homo sapiens]
 gi|3334749|emb|CAA04737.1|   MUC5AC protein [Homo sapiens]
          Length = 1081

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 39/184 (21%), Positives = 65/184 (35%), Gaps = 39/184 (21%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS----QECS----------------- 1013
            G CG    D KD+  T   +V +   E    W  S      C                  
Sbjct: 488  GQCGTCTNDRKDECRTPRGTVVASCSEMSGLWNVSIPDQPACHRPHPTPTTVGPTTVGST 547

Query: 1014 ----DTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC-ACD 1068
                 TV  T    + P         C+++    F  CH  + P  +++ C+ + C   D
Sbjct: 548  TVGPTTVGSTTVGPTTPPAPCLPSPICQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD 607

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSW--RKPNLCPVYCDYYNAPGECRWHYEPCGTVT 1126
            ++      C+++ +YA  C++  +C+ W  R  ++CP  C            Y+PCG   
Sbjct: 608  LD----VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV-------YQPCGPSN 656

Query: 1127 AKTC 1130
               C
Sbjct: 657  PSYC 660



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 35/116 (30%), Positives = 47/116 (40%), Gaps = 10/116 (8%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 574 CQLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 630

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPE 601
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPE
Sbjct: 631 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALREAGPITEGCFCPE 685



>gi|2135763|pir||A57534   mucin 5AC (clone L31) - human (fragment)
 gi|1052608|emb|CAA88307.1|   apomucin [Homo sapiens]
          Length = 1042

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 39/184 (21%), Positives = 64/184 (34%), Gaps = 39/184 (21%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS----QECS----------------- 1013
            G CG    D KD+  T   +V +   E    W  S      C                  
Sbjct: 357  GQCGTCTNDRKDECRTPRGTVVASCSEMSGLWNVSIPDQPACHRPHPTPTTVGPTTVGST 416

Query: 1014 ----DTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC-ACD 1068
                 TV  T    + P         C ++    F  CH  + P  +++ C+ + C   D
Sbjct: 417  TVGPTTVGSTTVGPTTPPAPCLPSPICHLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD 476

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSW--RKPNLCPVYCDYYNAPGECRWHYEPCGTVT 1126
            ++      C+++ +YA  C++  +C+ W  R  ++CP  C            Y+PCG   
Sbjct: 477  LD----VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV-------YQPCGPSN 525

Query: 1127 AKTC 1130
               C
Sbjct: 526  PSYC 529



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 11/126 (8%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C+ I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 443 CHLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 499

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPEDKIQ 605
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPE  + 
Sbjct: 500 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEG-MT 557

Query: 606 IFNASS 611
           +F+ S+
Sbjct: 558 LFSTSA 563



>gi|46397621|sp|P98088|MU5A_HUMAN   Mucin 5AC (Mucin 5 subtype AC, tracheobronchial) (Tracheobronchial
            mucin) (TBM) (Major airway glycoprotein)
          Length = 1233

 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 39/184 (21%), Positives = 64/184 (34%), Gaps = 39/184 (21%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS----QECS----------------- 1013
            G CG    D KD+  T   +V +   E    W  S      C                  
Sbjct: 640  GQCGTCTNDRKDECRTPRGTVVASCSEMSGLWNVSIPDQPACHRPHPTPTTVGPTTVGST 699

Query: 1014 ----DTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC-ACD 1068
                 TV  T    + P         C ++    F  CH  + P  +++ C+ + C   D
Sbjct: 700  TVGPTTVGSTTVGPTTPPAPCLPSPICHLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD 759

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSW--RKPNLCPVYCDYYNAPGECRWHYEPCGTVT 1126
            ++      C+++ +YA  C++  +C+ W  R  ++CP  C            Y+PCG   
Sbjct: 760  LD----VVCSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV-------YQPCGPSN 808

Query: 1127 AKTC 1130
               C
Sbjct: 809  PSYC 812



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 11/126 (8%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C+ I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 726 CHLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 782

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPEDKIQ 605
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPE  + 
Sbjct: 783 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALREAGPITEGCFCPEG-MT 840

Query: 606 IFNASS 611
           +F+ S+
Sbjct: 841 LFSTSA 846



>gi|190400|gb|AAA63246.1|   profilaggrin
          Length = 465

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 93/405 (22%), Positives = 151/405 (37%), Gaps = 45/405 (11%)

Query: 59  KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG 118
           +SR R+  GS  S+D+      +S   S DS+R     S      G A ++S D      
Sbjct: 64  ESRTRKRRGSRFSQDS------DSEGHSEDSERHSG--SASRNHHGSAWEQSRDVSRHPR 115

Query: 119 SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSR----ERWDAGNSRSEDS 174
           S  ED    G  + + SS  S  +    S   G T    +++R    ER  +G+ +S DS
Sbjct: 116 SHDEDRASHG--HSADSSRQSGTRHAETSSR-GQTASSHEQARSSPGERHGSGHQQSADS 172

Query: 175 PAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT 234
                 S     G G+  +A    VSD    G +G  +   EG+  +S   SVS   G  
Sbjct: 173 ------SRHSATGRGQASSA----VSDRGHRGSSGSQASDSEGHSENSDTQSVS-GHGQA 221

Query: 235 SFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG-------- 286
             R ++        +       SG+ G  + ++  +  S S     G    G        
Sbjct: 222 RLRQQSHQESARGRSGER----SGRSGSFLYQVSTHEQSDSAHGRTGTSTGGRQGSHHEQ 277

Query: 287 ----SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSA 342
               S  S+S E         G ++GG + +  +   N++G +G+        G  D+S 
Sbjct: 278 ARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRTGHSGSHHSHTTSQGRSDASH 337

Query: 343 RNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGN 401
                 S+     +    G   +H         ++  SS   + G   S G   S + G+
Sbjct: 338 GTSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGS 397

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEA 446
           + S DS S G  + ++    G++  N  G +    S  GS  P +
Sbjct: 398 SVSQDSDSQGHSEDSERWS-GSASRNHHG-SAQEQSRDGSRHPRS 440



>gi|37181955|gb|AAQ88781.1|   KMQK697 [Homo sapiens]
          Length = 596

 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 62/299 (20%), Positives = 111/299 (37%), Gaps = 25/299 (8%)

Query: 165 DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
           +A  + +E S +  TGSS +  GA           +  +S   +G+S+ T+ G+  +S+G
Sbjct: 19  EAATNSNETSTSANTGSSVISSGASTA-------TNSGSSVTSSGVSTATISGSSVTSNG 71

Query: 225 GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
            S+  +       SE      G   + ++ + +   G  I     N  S + S+ A    
Sbjct: 72  VSIVTN-------SEFHTTSSGISTATNSEFSTASSGISI---ATNSESSTTSSGASTAT 121

Query: 285 FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG-----DNGNSSKDFDGNGVG- 338
               S+ S   S +   G   T  GA        S  S       N  SS    G     
Sbjct: 122 NSESSTPSSGASTVTNSGSSVTSSGASTATNSESSTVSSRASTATNSESSTLSSGASTAT 181

Query: 339 --DSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVS 396
             DSS  +   +++  SE S    G+S     E S        +++ + +   S  S  +
Sbjct: 182 NSDSSTTSSGASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 241

Query: 397 DSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETNA 455
           +S   T S+ +G+    +S+      ++  N    T  SG+   ++   +T     + A
Sbjct: 242 NSESRTTSNGAGTATNSESSTTSSGASTATNSDSSTVSSGASTATNSESSTTSSGASTA 300



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 55/286 (19%), Positives = 109/286 (38%), Gaps = 17/286 (5%)

Query: 179 TGSSGLKLGAGKGDAAFGFEVSDS----NSFGDTGISSKTVEGNQTSSSGGSVSIDL--- 231
           T SSG+ +      +      S +    +S   +G S+ T  G+  +SSG S + +    
Sbjct: 97  TASSGISIATNSESSTTSSGASTATNSESSTPSSGASTVTNSGSSVTSSGASTATNSESS 156

Query: 232 -----GDTSFRSENQFVGGGS---LNSISNLWDSGQEGFGINEIG--GNGMSGSVSAEAG 281
                  T+  SE+  +  G+    NS S+   SG      +E     +G S + ++E+ 
Sbjct: 157 TVSSRASTATNSESSTLSSGASTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESS 216

Query: 282 FKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
                + ++++ E S         T   +      +G+  + ++  +S         DSS
Sbjct: 217 TVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSDSS 276

Query: 342 ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
             +   +++  SE S    G+S     E S T      +++ D +   S     ++S  +
Sbjct: 277 TVSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSDSSTTSSGAGTATNSESS 336

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEAT 447
           T SS   +    +S+       +  N    T  SG+   ++   +T
Sbjct: 337 TVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSESST 382



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 52/239 (21%), Positives = 96/239 (40%), Gaps = 31/239 (12%)

Query: 65  DAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDT 124
           D+ +  S  + A    +S++SSG S  T    S        A +    +  +G   + ++
Sbjct: 274 DSSTVSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSDSSTTSSGAGTATNS 333

Query: 125 PPGGFFYGSSSSGDSDKKKPLFSFEFGA-TGEDEDKSRERWDAGNSRSEDSPAVGTGSSG 183
                  G S+  +S+   P      GA T  + + S     A  + + +S  V +G+S 
Sbjct: 334 ESSTVSSGISTVTNSESSTP----SSGANTATNSESSTTSSGANTATNSESSTVSSGAS- 388

Query: 184 LKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL--------GDTS 235
                     A   E S ++S    G+S+ T   + T+SSG S + +           T+
Sbjct: 389 ---------TATNSESSTTSS----GVSTATNSESSTTSSGASTATNSDSSTTSSEASTA 435

Query: 236 FRSENQFVGGGSLNSISNLWDSGQEGFGINEI--GGNGMSGSVSAEAGFKGFGSDSSSS 292
             SE+  V  G +++++N  +S     G N     G+ ++ + S  A   G  + S S+
Sbjct: 436 TNSESSTVSSG-ISTVTNS-ESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA 492



>gi|56206538|emb|CAI18456.1|   chromosome 6 open reading frame 205 [Homo sapiens]
          Length = 626

 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 62/299 (20%), Positives = 111/299 (37%), Gaps = 25/299 (8%)

Query: 165 DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
           +A  + +E S +  TGSS +  GA           +  +S   +G+S+ T+ G+  +S+G
Sbjct: 19  EAATNSNETSTSANTGSSVISSGASTA-------TNSGSSVTSSGVSTATISGSSVTSNG 71

Query: 225 GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
            S+  +       SE      G   + ++ + +   G     I  N  S + S+ A    
Sbjct: 72  VSIVTN-------SEFHTTSSGISTATNSEFSTASSGI---SIATNSESSTTSSGASTAT 121

Query: 285 FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-----GDNGNSSKDFDGNGV-- 337
               S+ S   S +   G   T  GA        S  S       N  SS    G     
Sbjct: 122 NSESSTPSSGASTVTNSGSSVTSSGASTATNSESSTVSSRASTATNSESSTLSSGASTAT 181

Query: 338 -GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVS 396
             DSS  +   +++  SE S    G+S     E S        +++ + +   S  S  +
Sbjct: 182 NSDSSTTSSGASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 241

Query: 397 DSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETNA 455
           +S   T S+ +G+    +S+      ++  N    T  SG+   ++   +T     + A
Sbjct: 242 NSESRTTSNGAGTATNSESSTTSSGASTATNSDSSTVSSGASTATNSESSTTSSGASTA 300



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 76/370 (20%), Positives = 137/370 (37%), Gaps = 44/370 (11%)

Query: 83  SSSSGDSDRTKPFFSL---GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDS 139
           ++SSG S  T   FS    G+     +E  +  S  +  + SE + P       ++SG S
Sbjct: 82  TTSSGISTATNSEFSTASSGISIATNSESSTTSSGASTATNSESSTPSSGASTVTNSGSS 141

Query: 140 DKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEV 199
                      GA+     +S          S  S A  + SS L  GA           
Sbjct: 142 VTSS-------GASTATNSES------STVSSRASTATNSESSTLSSGASTA-------T 181

Query: 200 SDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQ 259
           +  +S   +G S+ T   + T+SSG S + +   ++  S        + NS S+   SG 
Sbjct: 182 NSDSSTTSSGASTATNSESSTTSSGASTATNSESSTVSSR----ASTATNSESSTTSSGA 237

Query: 260 EGFGINE--IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                +E     NG   + ++E+     G+ ++++ + S +       + G +     +S
Sbjct: 238 STATNSESRTTSNGAGTATNSESSTTSSGASTATNSDSSTV-------SSGASTATNSES 290

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
            +  SG +  ++ D      G  +A N        SE S    G+S     E S T    
Sbjct: 291 STTSSGASTATNSDSSTTSSGAGTATN--------SESSTTSSGASTATNSESSTTSSGA 342

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGS 437
             +++ D +   S     ++S  +T SS   +    +S+       +  N    T  SG+
Sbjct: 343 STATNSDSSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGA 402

Query: 438 EKGSHIPEAT 447
              ++   +T
Sbjct: 403 NTATNSESST 412



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 56/294 (19%), Positives = 111/294 (37%), Gaps = 17/294 (5%)

Query: 179 TGSSGLKLGAGKGDAAFGFEVSDS----NSFGDTGISSKTVEGNQTSSSGGSVSIDL--- 231
           T SSG+ +      +      S +    +S   +G S+ T  G+  +SSG S + +    
Sbjct: 97  TASSGISIATNSESSTTSSGASTATNSESSTPSSGASTVTNSGSSVTSSGASTATNSESS 156

Query: 232 -----GDTSFRSENQFVGGGS---LNSISNLWDSGQEGFGINEIG--GNGMSGSVSAEAG 281
                  T+  SE+  +  G+    NS S+   SG      +E     +G S + ++E+ 
Sbjct: 157 TVSSRASTATNSESSTLSSGASTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESS 216

Query: 282 FKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
                + ++++ E S         T   +      +G+  + ++  +S         DSS
Sbjct: 217 TVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSDSS 276

Query: 342 ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
             +   +++  SE S    G+S     + S T      +++ + +   S  S  ++S  +
Sbjct: 277 TVSSGASTATNSESSTTSSGASTATNSDSSTTSSGAGTATNSESSTTSSGASTATNSESS 336

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETNA 455
           T SS + +     S+       +  N    T  SG    ++   +TP      A
Sbjct: 337 TTSSGASTATNSDSSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTA 390



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 62/290 (21%), Positives = 111/290 (38%), Gaps = 36/290 (12%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           G    S S   S G+S++ + D           +  E+   S     A +  S  T +G 
Sbjct: 253 GTATNSESSTTSSGASTATNSDSSTVSSGASTATNSESSTTSSGASTATNSDSSTTSSGA 312

Query: 79  FF-----NSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGS 133
                  +S++SSG S  T    S        A +    +  +G   + ++       G 
Sbjct: 313 GTATNSESSTTSSGASTATNSESSTTSSGASTATNSDSSTTSSGAGTATNSESSTVSSGI 372

Query: 134 SSSGDSDKKKPLFSFEFGA-TGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGD 192
           S+  +S+   P      GA T  + + S     A  + + +S  V +G+S          
Sbjct: 373 STVTNSESSTP----SSGANTATNSESSTTSSGANTATNSESSTVSSGAS---------- 418

Query: 193 AAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL--------GDTSFRSENQFVG 244
            A   E S ++S    G+S+ T   + T+SSG S + +           T+  SE+  V 
Sbjct: 419 TATNSESSTTSS----GVSTATNSESSTTSSGASTATNSDSSTTSSEASTATNSESSTVS 474

Query: 245 GGSLNSISNLWDSGQEGFGINEI--GGNGMSGSVSAEAGFKGFGSDSSSS 292
            G +++++N  +S     G N     G+ ++ + S  A   G  + S S+
Sbjct: 475 SG-ISTVTNS-ESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSA 522



>gi|631314|pir||S42718   nuclear pore complex protein nup153 - human
 gi|406225|emb|CAA80982.1|   nuclear pore complex protein hnup153 [Homo sapiens]
 gi|1709214|sp|P49790|N153_HUMAN   Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa
            nucleoporin)
          Length = 1475

 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 112/475 (23%), Positives = 180/475 (37%), Gaps = 75/475 (15%)

Query: 29   FSYGSSSSGDLDRKKPL-------FSLEFG------SPGET----EDKSRQRQDAGSPKS 71
            F +G S+ G  ++K+ L       FS   G      +P  T    E+KS         KS
Sbjct: 998  FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057

Query: 72   EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS----GDSQDAGGSKSEDTPPG 127
                      S +   +   TK  FS G   P      S    G +++    + E     
Sbjct: 1058 ASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE---KQQEPVTST 1114

Query: 128  GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG----NSRSEDSPAVGTGSSG 183
               +G  +  +  K +P+FSF      +DE+ S+  +       + +  + PA  T + G
Sbjct: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174

Query: 184  LKLGA----GKGDAAFGFEVSDSNSFGDTGISSK--TVEGNQTSSSG--------GSVSI 229
             +       G     F F +++S+S   T  +S    + G+ TSSS         G  S 
Sbjct: 1175 AQTSTTADQGAAKPVFSF-LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233

Query: 230  DLGDTSFRSENQFVGGGSL--NSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKGFG 286
             +  ++F +  +     SL  +  S L  +   G  +   + G G S + +  +GF GFG
Sbjct: 1234 PVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGF-GFG 1292

Query: 287  SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGN--GVGDSSARN 344
            + ++SS   S  F FG G +   A   F   G+NQ+   G S      N  G G  S+  
Sbjct: 1293 ATTTSSSAGS-SFVFGTGPSAPSASPAF---GANQTPTFGQSQGASQPNPPGFGSISSST 1348

Query: 345  GF--ENSSGISEDSGVILGSSD-----QHEVELSRTGGNRKRSSDPDEAGNLSPG---SD 394
                  S       G +  SS      Q   + +   G    SS   + G+ +     ++
Sbjct: 1349 ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTN 1408

Query: 395  VSDSGGNTWSSDSG--------SGGGG----KSADELGVGASGLNEFGETGLSGS 437
             S SG  T+ ++S         SG GG    +S     VG++G N F  +G S S
Sbjct: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 1/107 (0%)

Query: 273 SGSVSAEAGFKGFG-SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           S     ++GFKGF  S SSS+   S  F+FG+  +  G       +G+ + GD G     
Sbjct: 876 SAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIG 935

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRK 378
              +    +    GF+ S  I +    +   S   EV+      N K
Sbjct: 936 VSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 52/202 (25%), Positives = 65/202 (32%), Gaps = 30/202 (14%)

Query: 122  EDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR--------- 170
            E   PG    F G  +S  S       SF+FG +      S+     GN +         
Sbjct: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKI 934

Query: 171  --SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVS 228
              S DS ++   S G K     GD  FG  VS  +   +    SK        SSG S  
Sbjct: 935  GVSSDSGSINPMSEGFKFSKPIGDFKFG--VSSESKPEEVKKDSKNDNFKFGLSSGLSNP 992

Query: 229  IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSD 288
            + L    F   N     G       L  S   GF      G G+  S  A A       +
Sbjct: 993  VSLTPFQFGVSNL----GQEEKKEELPKSSSAGFSF----GTGVINSTPAPANTIVTSEN 1044

Query: 289  SSSSVEKSWLFEFGLGETKGGA 310
             SS       F  G  ETK  +
Sbjct: 1045 KSS-------FNLGTIETKSAS 1059



>gi|55957596|emb|CAI16394.1|   nucleoporin 153kDa [Homo sapiens]
 gi|55957595|emb|CAI16393.1|   OTTHUMP00000039309 [Homo sapiens]
 gi|57208790|emb|CAI40946.1|   nucleoporin 153kDa [Homo sapiens]
 gi|57208789|emb|CAI40945.1|   OTTHUMP00000039309 [Homo sapiens]
 gi|55957699|emb|CAI12247.1|   nucleoporin 153kDa [Homo sapiens]
 gi|55957698|emb|CAI12246.1|   OTTHUMP00000039309 [Homo sapiens]
 gi|24430146|ref|NP_005115.2|   nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 112/475 (23%), Positives = 180/475 (37%), Gaps = 75/475 (15%)

Query: 29   FSYGSSSSGDLDRKKPL-------FSLEFG------SPGET----EDKSRQRQDAGSPKS 71
            F +G S+ G  ++K+ L       FS   G      +P  T    E+KS         KS
Sbjct: 998  FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057

Query: 72   EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS----GDSQDAGGSKSEDTPPG 127
                      S +   +   TK  FS G   P      S    G +++    + E     
Sbjct: 1058 ASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE---KQQEPVTST 1114

Query: 128  GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG----NSRSEDSPAVGTGSSG 183
               +G  +  +  K +P+FSF      +DE+ S+  +       + +  + PA  T + G
Sbjct: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174

Query: 184  LKLGA----GKGDAAFGFEVSDSNSFGDTGISSK--TVEGNQTSSSG--------GSVSI 229
             +       G     F F +++S+S   T  +S    + G+ TSSS         G  S 
Sbjct: 1175 AQTSTTADQGAAKPVFSF-LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233

Query: 230  DLGDTSFRSENQFVGGGSL--NSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKGFG 286
             +  ++F +  +     SL  +  S L  +   G  +   + G G S + +  +GF GFG
Sbjct: 1234 PVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGF-GFG 1292

Query: 287  SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGN--GVGDSSARN 344
            + ++SS   S  F FG G +   A   F   G+NQ+   G S      N  G G  S+  
Sbjct: 1293 ATTTSSSAGS-SFVFGTGPSAPSASPAF---GANQTPTFGQSQGASQPNPPGFGSISSST 1348

Query: 345  GF--ENSSGISEDSGVILGSSD-----QHEVELSRTGGNRKRSSDPDEAGNLSPG---SD 394
                  S       G +  SS      Q   + +   G    SS   + G+ +     ++
Sbjct: 1349 ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTN 1408

Query: 395  VSDSGGNTWSSDSG--------SGGGG----KSADELGVGASGLNEFGETGLSGS 437
             S SG  T+ ++S         SG GG    +S     VG++G N F  +G S S
Sbjct: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 1/107 (0%)

Query: 273 SGSVSAEAGFKGFG-SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           S     ++GFKGF  S SSS+   S  F+FG+  +  G       +G+ + GD G     
Sbjct: 876 SAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIG 935

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRK 378
              +    +    GF+ S  I +    +   S   EV+      N K
Sbjct: 936 VSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 52/202 (25%), Positives = 65/202 (32%), Gaps = 30/202 (14%)

Query: 122  EDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR--------- 170
            E   PG    F G  +S  S       SF+FG +      S+     GN +         
Sbjct: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKI 934

Query: 171  --SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVS 228
              S DS ++   S G K     GD  FG  VS  +   +    SK        SSG S  
Sbjct: 935  GVSSDSGSINPMSEGFKFSKPIGDFKFG--VSSESKPEEVKKDSKNDNFKFGLSSGLSNP 992

Query: 229  IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSD 288
            + L    F   N     G       L  S   GF      G G+  S  A A       +
Sbjct: 993  VSLTPFQFGVSNL----GQEEKKEELPKSSSAGFSF----GTGVINSTPAPANTIVTSEN 1044

Query: 289  SSSSVEKSWLFEFGLGETKGGA 310
             SS       F  G  ETK  +
Sbjct: 1045 KSS-------FNLGTIETKSAS 1059



>gi|31418202|gb|AAH52965.1|   Nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 112/475 (23%), Positives = 180/475 (37%), Gaps = 75/475 (15%)

Query: 29   FSYGSSSSGDLDRKKPL-------FSLEFG------SPGET----EDKSRQRQDAGSPKS 71
            F +G S+ G  ++K+ L       FS   G      +P  T    E+KS         KS
Sbjct: 998  FQFGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTIETKS 1057

Query: 72   EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS----GDSQDAGGSKSEDTPPG 127
                      S +   +   TK  FS G   P      S    G +++    + E     
Sbjct: 1058 ASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEE---KQQEPVTST 1114

Query: 128  GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAG----NSRSEDSPAVGTGSSG 183
               +G  +  +  K +P+FSF      +DE+ S+  +       + +  + PA  T + G
Sbjct: 1115 SLVFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFG 1174

Query: 184  LKLGA----GKGDAAFGFEVSDSNSFGDTGISSK--TVEGNQTSSSG--------GSVSI 229
             +       G     F F +++S+S   T  +S    + G+ TSSS         G  S 
Sbjct: 1175 AQTSTTADQGAAKPVFSF-LNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSN 1233

Query: 230  DLGDTSFRSENQFVGGGSL--NSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKGFG 286
             +  ++F +  +     SL  +  S L  +   G  +   + G G S + +  +GF GFG
Sbjct: 1234 PVSSSAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGF-GFG 1292

Query: 287  SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGN--GVGDSSARN 344
            + ++SS   S  F FG G +   A   F   G+NQ+   G S      N  G G  S+  
Sbjct: 1293 ATTTSSSAGS-SFVFGTGPSAPSASPAF---GANQTPTFGQSQGASQPNPPGFGSISSST 1348

Query: 345  GF--ENSSGISEDSGVILGSSD-----QHEVELSRTGGNRKRSSDPDEAGNLSPG---SD 394
                  S       G +  SS      Q   + +   G    SS   + G+ +     ++
Sbjct: 1349 ALFPTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTN 1408

Query: 395  VSDSGGNTWSSDSG--------SGGGG----KSADELGVGASGLNEFGETGLSGS 437
             S SG  T+ ++S         SG GG    +S     VG++G N F  +G S S
Sbjct: 1409 NSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFS 1463



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 1/107 (0%)

Query: 273 SGSVSAEAGFKGFG-SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           S     ++GFKGF  S SSS+   S  F+FG+  +  G       +G+ + GD G     
Sbjct: 876 SAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIG 935

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRK 378
              +    +    GF+ S  I +    +   S   EV+      N K
Sbjct: 936 VSSDSGSINPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFK 982



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 52/202 (25%), Positives = 65/202 (32%), Gaps = 30/202 (14%)

Query: 122  EDTPPG--GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR--------- 170
            E   PG    F G  +S  S       SF+FG +      S+     GN +         
Sbjct: 875  ESAKPGTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKI 934

Query: 171  --SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVS 228
              S DS ++   S G K     GD  FG  VS  +   +    SK        SSG S  
Sbjct: 935  GVSSDSGSINPMSEGFKFSKPIGDFKFG--VSSESKPEEVKKDSKNDNFKFGLSSGLSNP 992

Query: 229  IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSD 288
            + L    F   N     G       L  S   GF      G G+  S  A A       +
Sbjct: 993  VSLTPFQFGVSNL----GQEEKKEELPKSSSAGFSF----GTGVINSTPAPANTIVTSEN 1044

Query: 289  SSSSVEKSWLFEFGLGETKGGA 310
             SS       F  G  ETK  +
Sbjct: 1045 KSS-------FNLGTIETKSAS 1059



>gi|21707329|gb|AAH33831.1|   Unknown (protein for IMAGE:3852667) [Homo sapiens]
          Length = 574

 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 11/126 (8%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I+   FE C  V      Y+  C+ + C   D    C +    + LCAS        
Sbjct: 67  CQLILSKVFEPCHTVIPPLLFYEG-CVFDRCHMTDLDVVCSSLELYAALCASHD--ICID 123

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATC------SNVAPFQDSECVSGCTCPEDKIQ 605
           WR  +  +C    CP   +Y+ CGPSNP+ C      S  A  +      GC CPE  + 
Sbjct: 124 WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSASLGALPEAGPITEGCFCPEG-MT 181

Query: 606 IFNASS 611
           +F+ S+
Sbjct: 182 LFSTSA 187



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 23/98 (23%), Positives = 45/98 (45%), Gaps = 14/98 (14%)

Query: 1036 CEILRDSTFRDCHNKVDPSAYHDVCIEEAC-ACDMEGKYLGFCTAVAMYAEACSAVGVCV 1094
            C+++    F  CH  + P  +++ C+ + C   D++      C+++ +YA  C++  +C+
Sbjct: 67   CQLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTDLD----VVCSSLELYAALCASHDICI 122

Query: 1095 SW--RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
             W  R  ++CP  C            Y+PCG      C
Sbjct: 123  DWRGRTGHMCPFTCPADKV-------YQPCGPSNPSYC 153



>gi|107415|pir||A35938   profilaggrin - human (fragments)
          Length = 2248

 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 101/460 (21%), Positives = 157/460 (34%), Gaps = 50/460 (10%)

Query: 23   ASRSGGFSYGSSSSGDLDR--KKPLFSLEFGSPGETEDKSRQ----RQDAGSPKS--EDT 74
            +SR  G   G +SS   DR  +    S      G +ED   Q    ++ AGS +   +++
Sbjct: 820  SSRHSGIGRGQASSAVRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQES 879

Query: 75   PAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSS 134
              G     S  SG              A G+    +G  Q +   ++ D+      + +S
Sbjct: 880  TRGRSQGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR----HSAS 935

Query: 135  SSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLG------- 187
              G    +    S   G  G   ++S +R  +G+S S  S     G S    G       
Sbjct: 936  QEGQDTIRAHPGSRRGGRQGSHHEQSVDR--SGHSGSHHSHTTSQGRSDASHGQSGSGSH 993

Query: 188  ----------AGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID------- 230
                      +G G       V DS   G +G  +   EG+   S   SVS         
Sbjct: 994  HQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAQGQAGPHQ 1053

Query: 231  ---LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
                  T  RS  +    GS     +  +  +   G       G  GS   +A      S
Sbjct: 1054 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRARTSTRGRQGSHHEQARDS---S 1110

Query: 288  DSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFE 347
              S+S E         G + GG   +  +   N +G +G+        G  D+S      
Sbjct: 1111 RHSTSQEGQDTIRGHPGPSSGGRHGSHYEQSVNSTGHSGSHHSHTTSQGRSDASHGTSGS 1170

Query: 348  NSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTWSSD 406
             S+     +    G   +H     +   +   SS   +AG   S GS  S + G+++S D
Sbjct: 1171 RSASRETHNEEQSGDGSRHSGSRHQEASSWADSSGHSQAGQGESSGSRTSRNQGSSFSQD 1230

Query: 407  SGSGGGGKSADELGVGASGLNEFG---ETGLSGS-EKGSH 442
            S S G  + ++    G++  N  G   E    GS   GSH
Sbjct: 1231 SDSQGQSEDSERRS-GSASRNHRGSAREQSRDGSRHPGSH 1269



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 85/419 (20%), Positives = 142/419 (33%), Gaps = 22/419 (5%)

Query: 17   KDGKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPA 76
            +D     SR    S     S D D +      + GS  E    S Q    G  +     +
Sbjct: 1340 RDSGHRGSRGSQASDNEGHSEDSDTQSVAGQRQAGSHHE----SHQESTRGQSRETSGRS 1395

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGL-GAPGKAEDKSGDS-QDAGGSKSEDTPPGGFFYGSS 134
            G F    S+   S+ +  +      G  G   +++ DS + +   + +DT  G   +   
Sbjct: 1396 GSFLYQVSTHEQSESSHGWSGTSTRGRQGSHHEQAQDSSRHSASQEGQDTIHG---HPGG 1452

Query: 135  SSGDSDKKKPLFSFEFGATGEDEDKSRE-RWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA 193
             S DS ++      E  + G+      + R  AG             S    +G G+  +
Sbjct: 1453 HSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQQSADSSRHAGIGHGQASS 1512

Query: 194  AFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISN 253
            A    V DS   G  G  +   EG+   S   SVS        +  +Q    G     S 
Sbjct: 1513 A----VRDSGHRGYRGSQATDSEGHSEDSDTQSVSAQGQAGPHQQAHQESARGQSGESSG 1568

Query: 254  LWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL-------GET 306
               S       +E   +    SV +  G +G   D +    +    + G        G +
Sbjct: 1569 RSGSFLYQVSTHEQSESTHGQSVPSTGGRQGSHHDQAQDSSRHSASQEGQDTIRGHPGSS 1628

Query: 307  KGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQH 366
            +GG   +  +   ++SG +G+        G  D+S  +    S+     +    G   +H
Sbjct: 1629 RGGRHGSHYEQSVDRSGHSGSHHSHTTSQGRSDASHGSSGSRSASRQTRNEEQSGDGSRH 1688

Query: 367  EVELSRTGGNRKRSSDPDEAG-NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
                      +  SS   +AG   S G   S + G++ S DS S G  + ++     AS
Sbjct: 1689 SRSHHHEASTQAESSRHSQAGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS 1747



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 45/422 (10%)

Query: 23  ASRSGGFSYGSSSSGDLDRKK-PLFSLEFGSPGETEDKSRQ----------------RQD 65
           +SR      G SS     R +   FS +  S  ++ED  R+                R  
Sbjct: 375 SSRHSQVGQGESSGSRTSRNQGSSFSQDRDSQAQSEDSERRSASASRNHRGSAQEQSRDG 434

Query: 66  AGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPG---KAEDKSGDSQDAGGSKSE 122
           +  P S      G   S+ SS  S       S G  A     +A   +G+   +G  +S 
Sbjct: 435 SRHPGSHQEDRAGHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGHQQSA 494

Query: 123 DTPP-GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
           D+    G  +G +SS   D     +S    +  E   ++ +       R   S       
Sbjct: 495 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQE 554

Query: 182 S--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDLGDTSF 236
           S  G   G      +F ++VS       T   S++  G    S+    GS      D+S 
Sbjct: 555 STRGQSRGRSGRSGSFLYQVS-------THEQSESAHGRSAPSTRRRQGSHHDQARDSSR 607

Query: 237 RSENQFVGGGSLNSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKG-----FGSDSS 290
            S +Q  G  ++         G++G    + +  +G SGS  +    +G      G+  S
Sbjct: 608 HSASQ-EGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASHGTSGS 666

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
            S  +    E   G+  G          ++   D+   S+   G   G  ++RN     S
Sbjct: 667 RSASRQTRDEEQSGD--GTRHSGSHHQEASTQADSSRHSQVGQGQSAGSRTSRN---QGS 721

Query: 351 GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSG 410
            +S+D      S D      S +  +R  + +    G+  PGS   D  G+  S+DS S 
Sbjct: 722 SVSQDRDSEGQSEDSERHSGSASRNHRGSAQEQSRDGSRHPGSHDEDRAGHRQSADSSSQ 781

Query: 411 GG 412
            G
Sbjct: 782 SG 783



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 89/395 (22%), Positives = 145/395 (36%), Gaps = 26/395 (6%)

Query: 61  RQRQDAGSPKSEDTPAGGFFNSSSSSGDSD-RTKPFFSLGLGAPGKAEDKSGDSQDAGG- 118
           + R  +  P+S D       +S+ SS  S  R     S G  A    + +S   +  G  
Sbjct: 106 QSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSAGERHGSH 165

Query: 119 --SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPA 176
               ++ +   G  +G +S+  SD     +     +  E   +  +       R   S  
Sbjct: 166 HQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQASDNEGHSEDSDSQSVAGQRQARSRH 225

Query: 177 VGTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDL 231
                S  G   G      +F ++VS       T   S++  G   +S+G   GS     
Sbjct: 226 QSHQESTRGRSRGGSGRSGSFLYQVS-------THEQSESSHGWARTSTGRRQGSRHDQA 278

Query: 232 GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGN-GMSGSVSAEAGFKGFGSDSS 290
            D+S  S +Q  G  ++++       G+ G+   +   + G SGS  +    +G  SD+S
Sbjct: 279 QDSSRHSTSQ-QGQDTIHAHPGSRRGGRHGYHHEQSADSTGHSGSQHSHTTTQG-RSDAS 336

Query: 291 --SSVEKSWLFEFGLGETKGGAEFNFRDSGSN-QSGDNGNSSKDFDGNGVGDSS-ARNGF 346
             SS  +S   E    E  G      R SGS+ Q       S      G G+SS +R   
Sbjct: 337 RGSSGSRSTSRETRDQEQSGDGS---RHSGSHHQEASTRAESSRHSQVGQGESSGSRTSR 393

Query: 347 ENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSD 406
              S  S+D      S D      S +  +R  + +    G+  PGS   D  G+  S++
Sbjct: 394 NQGSSFSQDRDSQAQSEDSERRSASASRNHRGSAQEQSRDGSRHPGSHQEDRAGHRQSAE 453

Query: 407 SGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           S S  G   A+    G +  ++      +G   GS
Sbjct: 454 SSSQSGTHHAENSSGGQAASSQEQARSSAGERHGS 488



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 78/346 (22%), Positives = 122/346 (35%), Gaps = 35/346 (10%)

Query: 76   AGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS 135
            +G   + ++S G SD      S G    G    +S DS    G         G    SS+
Sbjct: 968  SGSHHSHTTSQGRSDA-----SHGQSGSGSHHQQSADSSRHSGI--------GHGQASSA 1014

Query: 136  SGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAF 195
              DS  +    S    + G  ED   +   A         +    + G   G      +F
Sbjct: 1015 VRDSGHRGSSGSQASDSEGHSEDSDTQSVSAQGQAGPHQQSHQESTRGRSAGRSGRSGSF 1074

Query: 196  GFEVSDSNSFGDTGISSKTVEGN-QTSSSG--GSVSIDLGDTSFRSENQFVGGGSLNSIS 252
             ++VS       T   S++  G  +TS+ G  GS      D+S  S +Q  G  ++    
Sbjct: 1075 LYQVS-------THEQSESAHGRARTSTRGRQGSHHEQARDSSRHSTSQ-EGQDTIRGHP 1126

Query: 253  NLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKG-----FGSDSSSSVEKSWLFEFGLGET 306
                 G+ G    + +   G SGS  +    +G      G+  S S  +    E   G+ 
Sbjct: 1127 GPSSGGRHGSHYEQSVNSTGHSGSHHSHTTSQGRSDASHGTSGSRSASRETHNEEQSGD- 1185

Query: 307  KGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQH 366
             G      R   ++   D+   S+   G   G  ++RN     S  S+DS     S D  
Sbjct: 1186 -GSRHSGSRHQEASSWADSSGHSQAGQGESSGSRTSRN---QGSSFSQDSDSQGQSEDSE 1241

Query: 367  EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGG 412
                S +  +R  + +    G+  PGS   D  G+  S+DS    G
Sbjct: 1242 RRSGSASRNHRGSAREQSRDGSRHPGSHHEDRAGHGHSADSSRQSG 1287



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 108/460 (23%), Positives = 166/460 (36%), Gaps = 67/460 (14%)

Query: 58   DKSRQRQDAGSPKSEDTPAGGFFNSS-SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA 116
            + S   Q A S +   + AG    S    S DS R       G+G  G+A     DS   
Sbjct: 1791 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHS-----GIGH-GQASSAVRDSGHR 1844

Query: 117  GGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKS-RERWDAGNSRS---- 171
            G S S+ +   G       S DSD +      + G+  +   +S R R   G+ RS    
Sbjct: 1845 GSSGSQASDSEGH------SEDSDTQSVSAHGQAGSHQQSHQESTRGRSQEGSGRSGSFL 1898

Query: 172  -----EDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGS 226
                  +      G +G   G  +G        S  +S    G    T+ G+  S  GG 
Sbjct: 1899 YQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG--QDTIRGHPGSRRGGR 1956

Query: 227  VSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA----GF 282
                    S+  ++    G S +  S+    G+      + G    S     E     G 
Sbjct: 1957 QG------SYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS 2010

Query: 283  KGFGS---DSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGD 339
            +  GS   ++S+  + S   + G GE+ G      R  GS+ S D+ + +   D     +
Sbjct: 2011 RHSGSRHHEASTQADSSRHSQSGQGESAGSRRS--RRQGSSVSQDSDSEAYPEDSERRSE 2068

Query: 340  SSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG 399
            S++RN   +S   S D     GSS +      ++   +  SS   E G+ S  S   DS 
Sbjct: 2069 SASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLS--QDSA 2126

Query: 400  GNTWSSDSGSGGGGKS------ADELGVGASGL-----------NEFGETGLSGSEKGSH 442
             ++     GS     S        E   G SGL            ++GE+G   S+ GS 
Sbjct: 2127 YHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQHGSV 2186

Query: 443  IPEATP-KYSETNAI-----IGQDINEHIAN--SKIPGDC 474
               + P  + E + I      G+D   + A   +K PG C
Sbjct: 2187 SYNSNPVLFKERSDICKASAFGKDHPRYYATYINKDPGLC 2226



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 85/394 (21%), Positives = 132/394 (33%), Gaps = 33/394 (8%)

Query: 32   GSSSSGDLDRKKPLFSLE--FGSPGETEDKSRQRQDAGS---PKSEDTPAGGFFNSSSSS 86
            GSS S D D +      E   GS       S Q Q       P S      G  +S+ SS
Sbjct: 1723 GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHRHSAESS 1782

Query: 87   GDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS----KSEDTPPGGFFYGSSSSG--DSD 140
              S       S G  A    E     + +  GS     ++ +   G  +G +SS   DS 
Sbjct: 1783 DQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 1842

Query: 141  KKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVS 200
             +    S    + G  ED   +   A         +    + G          +F ++VS
Sbjct: 1843 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGSHQQSHQESTRGRSQEGSGRSGSFLYQVS 1902

Query: 201  DSNSFGDTGISSKTVEGNQTSSSGG---SVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
                   T   S++  G    S+GG   S      D+S  S +Q  G  ++         
Sbjct: 1903 -------THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQ-EGQDTIRGHPGSRRG 1954

Query: 258  GQEG-FGINEIGGNGMSGSVSAEAGFKG-----FGSDSSSSVEKSWLFEFGLGETKGGAE 311
            G++G +    +  +G SGS  +    +G      G   S S  +    E   G+  G   
Sbjct: 1955 GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD--GSRH 2012

Query: 312  FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELS 371
               R   ++   D+   S+   G   G   +R      S +S+DS       D      S
Sbjct: 2013 SGSRHHEASTQADSSRHSQSGQGESAGSRRSRR---QGSSVSQDSDSEAYPEDSERRSES 2069

Query: 372  RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
             +  +   S +    G+  PGS   D+  +  SS
Sbjct: 2070 ASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSS 2103



>gi|29653|emb|CAA45535.1|   putative oncogene [Homo sapiens]
 gi|284374|pir||S26058   probable transforming protein (can) - human
 gi|548384|sp|P35658|N214_HUMAN   Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa
            nucleoporin) (CAN protein)
          Length = 2090

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 94/387 (24%), Positives = 136/387 (35%), Gaps = 74/387 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1714 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1770

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1771 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1826

Query: 139  SDKKKPLFSF----EFGATGEDEDKSRERWDAG-----NSRSEDSPAVGTGSSGLKLGAG 189
            +      FSF     FG++       +     G      S S      G+G++G   G  
Sbjct: 1827 TTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFF 1886

Query: 190  KG-------DAA-----------FGFEVSD--SNSFGDTGISSKTVEGNQTSS------- 222
             G       DAA           FG   +   SN FG++G  +KT  G  +SS       
Sbjct: 1887 SGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG--AKTFGGFASSSFGEQKPT 1944

Query: 223  ---SGGSVSIDLGDTSFRSENQFVGGGSLNSI-SNLWDSGQEGFG-----------INEI 267
               S G  S+      F S N+  G G+     S     G  GFG            + +
Sbjct: 1945 GTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPL 2004

Query: 268  GGNG----MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            G  G      G+ +A AG  GFGS S+++        FG   ++    F    S S Q+ 
Sbjct: 2005 GSTGGKVFGEGTAAASAGGFGFGSSSNTT-------SFGTLASQNAPTFG---SLSQQTS 2054

Query: 324  DNGNSSKDFDGNGVGDSSARNGFENSS 350
              G  S  F G G G      G  NSS
Sbjct: 2055 GFGTQSSGFSGFGSGTGGFSFGSNNSS 2081



>gi|56208558|emb|CAI20354.1|   OTTHUMP00000028832 [Homo sapiens]
 gi|56202954|emb|CAI18813.1|   OTTHUMP00000028832 [Homo sapiens]
 gi|56202698|emb|CAI18982.1|   OTTHUMP00000028832 [Homo sapiens]
          Length = 1759

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 112/516 (21%), Positives = 178/516 (34%), Gaps = 118/516 (22%)

Query: 32  GSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQD--------AGSPKSE----DTPAGGF 79
           G+S  G L+      S +  + G+T  + + + +        +G  +++    D P  G 
Sbjct: 354 GTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGN 413

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS---- 135
            NS + S  +         G+G    +      SQ  G  K+      G   G S     
Sbjct: 414 TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 473

Query: 136 SGDSDKKKPLFSFEFGATGEDEDKSRERW-DAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
           SG S+          G  G +  +  + W  A   +S  S      ++    G   G   
Sbjct: 474 SGQSNS---------GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG---GSWN 521

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNL 254
           FG + S+ N +G+    +  V   +     GS  + +G+ S        G    NS +  
Sbjct: 522 FGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWS--------GPNQPNSSTGA 573

Query: 255 WDSGQEGFGINEIGGNGM-------SGSVSAEAGFKGFG-------SDSSSSVEKSW--- 297
           WD+ Q+G  + E  GN         S S  +E G +  G       SDS +S  +S+   
Sbjct: 574 WDN-QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPT 632

Query: 298 ---------------------LFEFGLGETK------GGAEFNFRDSGSNQSGDNG---N 327
                                L   G G+T+         E   R  G +  G  G    
Sbjct: 633 HPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESA 692

Query: 328 SSKDFDGNGVGDSSA-----RNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRKRS 380
           +++  +  G GD+ +     ++G+   S  +E  D     G +D      S  GG R   
Sbjct: 693 ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE 752

Query: 381 SDPDEAGNLSPGSDVSDSGGNT----WSSDSGSGGGGKSADEL--------------GVG 422
             P  + N +P  D    GG      WS  SG  G G+  D+               G G
Sbjct: 753 KTP-SSWNENPSKDQGWGGGRQPNQGWS--SGKNGWGEEVDQTKNSNWESSASKPVSGWG 809

Query: 423 ASGLNEFGETGLSG-----SEKGSHIPEATPKYSET 453
             G NE G  G  G     S+ G    + +P ++ET
Sbjct: 810 EGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 845



>gi|57208869|emb|CAI41111.1|   OTTHUMP00000064563 [Homo sapiens]
 gi|33946327|ref|NP_005076.3|   nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 94/387 (24%), Positives = 136/387 (35%), Gaps = 74/387 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1714 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1770

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1771 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1826

Query: 139  SDKKKPLFSF----EFGATGEDEDKSRERWDAG-----NSRSEDSPAVGTGSSGLKLGAG 189
            +      FSF     FG++       +     G      S S      G+G++G   G  
Sbjct: 1827 TTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFF 1886

Query: 190  KG-------DAA-----------FGFEVSD--SNSFGDTGISSKTVEGNQTSS------- 222
             G       DAA           FG   +   SN FG++G  +KT  G  +SS       
Sbjct: 1887 SGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG--AKTFGGFASSSFGEQKPT 1944

Query: 223  ---SGGSVSIDLGDTSFRSENQFVGGGSLNSI-SNLWDSGQEGFG-----------INEI 267
               S G  S+      F S N+  G G+     S     G  GFG            + +
Sbjct: 1945 GTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPL 2004

Query: 268  GGNG----MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            G  G      G+ +A AG  GFGS S+++        FG   ++    F    S S Q+ 
Sbjct: 2005 GSTGGKVFGEGTAAASAGGFGFGSSSNTT-------SFGTLASQNAPTFG---SLSQQTS 2054

Query: 324  DNGNSSKDFDGNGVGDSSARNGFENSS 350
              G  S  F G G G      G  NSS
Sbjct: 2055 GFGTQSSGFSGFGSGTGGFSFGSNNSS 2081



>gi|57208867|emb|CAI41109.1|   nucleoporin 214kDa [Homo sapiens]
          Length = 1684

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 94/387 (24%), Positives = 136/387 (35%), Gaps = 74/387 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1308 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1364

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1365 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1420

Query: 139  SDKKKPLFSF----EFGATGEDEDKSRERWDAG-----NSRSEDSPAVGTGSSGLKLGAG 189
            +      FSF     FG++       +     G      S S      G+G++G   G  
Sbjct: 1421 TTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFF 1480

Query: 190  KG-------DAA-----------FGFEVSD--SNSFGDTGISSKTVEGNQTSS------- 222
             G       DAA           FG   +   SN FG++G  +KT  G  +SS       
Sbjct: 1481 SGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG--AKTFGGFASSSFGEQKPT 1538

Query: 223  ---SGGSVSIDLGDTSFRSENQFVGGGSLNSI-SNLWDSGQEGFG-----------INEI 267
               S G  S+      F S N+  G G+     S     G  GFG            + +
Sbjct: 1539 GTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPL 1598

Query: 268  GGNG----MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            G  G      G+ +A AG  GFGS S+++        FG   ++    F    S S Q+ 
Sbjct: 1599 GSTGGKVFGEGTAAASAGGFGFGSSSNTT-------SFGTLASQNAPTFG---SLSQQTS 1648

Query: 324  DNGNSSKDFDGNGVGDSSARNGFENSS 350
              G  S  F G G G      G  NSS
Sbjct: 1649 GFGTQSSGFSGFGSGTGGFSFGSNNSS 1675



>gi|51476025|ref|XP_039385.2|   PREDICTED: KIAA1093 protein [Homo sapiens]
          Length = 1776

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 112/516 (21%), Positives = 178/516 (34%), Gaps = 118/516 (22%)

Query: 32  GSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQD--------AGSPKSE----DTPAGGF 79
           G+S  G L+      S +  + G+T  + + + +        +G  +++    D P  G 
Sbjct: 318 GTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGN 377

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS---- 135
            NS + S  +         G+G    +      SQ  G  K+      G   G S     
Sbjct: 378 TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 437

Query: 136 SGDSDKKKPLFSFEFGATGEDEDKSRERW-DAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
           SG S+          G  G +  +  + W  A   +S  S      ++    G   G   
Sbjct: 438 SGQSNS---------GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG---GSWN 485

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNL 254
           FG + S+ N +G+    +  V   +     GS  + +G+ S        G    NS +  
Sbjct: 486 FGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWS--------GPNQPNSSTGA 537

Query: 255 WDSGQEGFGINEIGGNGM-------SGSVSAEAGFKGFG-------SDSSSSVEKSW--- 297
           WD+ Q+G  + E  GN         S S  +E G +  G       SDS +S  +S+   
Sbjct: 538 WDN-QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPT 596

Query: 298 ---------------------LFEFGLGETK------GGAEFNFRDSGSNQSGDNG---N 327
                                L   G G+T+         E   R  G +  G  G    
Sbjct: 597 HPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESA 656

Query: 328 SSKDFDGNGVGDSSA-----RNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRKRS 380
           +++  +  G GD+ +     ++G+   S  +E  D     G +D      S  GG R   
Sbjct: 657 ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE 716

Query: 381 SDPDEAGNLSPGSDVSDSGGNT----WSSDSGSGGGGKSADEL--------------GVG 422
             P  + N +P  D    GG      WS  SG  G G+  D+               G G
Sbjct: 717 KTP-SSWNENPSKDQGWGGGRQPNQGWS--SGKNGWGEEVDQTKNSNWESSASKPVSGWG 773

Query: 423 ASGLNEFGETGLSG-----SEKGSHIPEATPKYSET 453
             G NE G  G  G     S+ G    + +P ++ET
Sbjct: 774 EGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 809



>gi|41016075|dbj|BAD07398.1|   KIAA0023 splice variant 1 [Homo sapiens]
          Length = 2091

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 94/387 (24%), Positives = 136/387 (35%), Gaps = 74/387 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1715 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1771

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1772 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1827

Query: 139  SDKKKPLFSF----EFGATGEDEDKSRERWDAG-----NSRSEDSPAVGTGSSGLKLGAG 189
            +      FSF     FG++       +     G      S S      G+G++G   G  
Sbjct: 1828 TTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGGGFF 1887

Query: 190  KG-------DAA-----------FGFEVSD--SNSFGDTGISSKTVEGNQTSS------- 222
             G       DAA           FG   +   SN FG++G  +KT  G  +SS       
Sbjct: 1888 SGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG--AKTFGGFASSSFGEQKPT 1945

Query: 223  ---SGGSVSIDLGDTSFRSENQFVGGGSLNSI-SNLWDSGQEGFG-----------INEI 267
               S G  S+      F S N+  G G+     S     G  GFG            + +
Sbjct: 1946 GTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPL 2005

Query: 268  GGNG----MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            G  G      G+ +A AG  GFGS S+++        FG   ++    F    S S Q+ 
Sbjct: 2006 GSTGGKVFGEGTAAASAGGFGFGSSSNTT-------SFGTLASQNAPTFG---SLSQQTS 2055

Query: 324  DNGNSSKDFDGNGVGDSSARNGFENSS 350
              G  S  F G G G      G  NSS
Sbjct: 2056 GFGTQSSGFSGFGSGTGGFSFGSNNSS 2082



>gi|38258268|sp|Q9UPQ9|K1093_HUMAN   Protein KIAA1093
          Length = 1723

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 112/516 (21%), Positives = 178/516 (34%), Gaps = 118/516 (22%)

Query: 32  GSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQD--------AGSPKSE----DTPAGGF 79
           G+S  G L+      S +  + G+T  + + + +        +G  +++    D P  G 
Sbjct: 318 GTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGN 377

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS---- 135
            NS + S  +         G+G    +      SQ  G  K+      G   G S     
Sbjct: 378 TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 437

Query: 136 SGDSDKKKPLFSFEFGATGEDEDKSRERW-DAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
           SG S+          G  G +  +  + W  A   +S  S      ++    G   G   
Sbjct: 438 SGQSNS---------GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG---GSWN 485

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNL 254
           FG + S+ N +G+    +  V   +     GS  + +G+ S        G    NS +  
Sbjct: 486 FGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWS--------GPNQPNSSTGA 537

Query: 255 WDSGQEGFGINEIGGNGM-------SGSVSAEAGFKGFG-------SDSSSSVEKSW--- 297
           WD+ Q+G  + E  GN         S S  +E G +  G       SDS +S  +S+   
Sbjct: 538 WDN-QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPT 596

Query: 298 ---------------------LFEFGLGETK------GGAEFNFRDSGSNQSGDNG---N 327
                                L   G G+T+         E   R  G +  G  G    
Sbjct: 597 HPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESA 656

Query: 328 SSKDFDGNGVGDSSA-----RNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRKRS 380
           +++  +  G GD+ +     ++G+   S  +E  D     G +D      S  GG R   
Sbjct: 657 ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE 716

Query: 381 SDPDEAGNLSPGSDVSDSGGNT----WSSDSGSGGGGKSADEL--------------GVG 422
             P  + N +P  D    GG      WS  SG  G G+  D+               G G
Sbjct: 717 KTP-SSWNENPSKDQGWGGGRQPNQGWS--SGKNGWGEEVDQTKNSNWESSASKPVSGWG 773

Query: 423 ASGLNEFGETGLSG-----SEKGSHIPEATPKYSET 453
             G NE G  G  G     S+ G    + +P ++ET
Sbjct: 774 EGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 809



>gi|14133235|dbj|BAA83045.2|   KIAA1093 protein [Homo sapiens]
          Length = 1727

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 112/516 (21%), Positives = 178/516 (34%), Gaps = 118/516 (22%)

Query: 32  GSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQD--------AGSPKSE----DTPAGGF 79
           G+S  G L+      S +  + G+T  + + + +        +G  +++    D P  G 
Sbjct: 323 GTSRKGALETDNSNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGN 382

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS---- 135
            NS + S  +         G+G    +      SQ  G  K+      G   G S     
Sbjct: 383 TNSLNLSSPNPMENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTV 442

Query: 136 SGDSDKKKPLFSFEFGATGEDEDKSRERW-DAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
           SG S+          G  G +  +  + W  A   +S  S      ++    G   G   
Sbjct: 443 SGQSNS---------GNNGNNGKEREDSWKGASVQKSTGSKNDSWDNNNRSTG---GSWN 490

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNL 254
           FG + S+ N +G+    +  V   +     GS  + +G+ S        G    NS +  
Sbjct: 491 FGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSDELKIGEWS--------GPNQPNSSTGA 542

Query: 255 WDSGQEGFGINEIGGNGM-------SGSVSAEAGFKGFG-------SDSSSSVEKSW--- 297
           WD+ Q+G  + E  GN         S S  +E G +  G       SDS +S  +S+   
Sbjct: 543 WDN-QKGHPLPENQGNAQAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPT 601

Query: 298 ---------------------LFEFGLGETK------GGAEFNFRDSGSNQSGDNG---N 327
                                L   G G+T+         E   R  G +  G  G    
Sbjct: 602 HPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEEVPRPEGKSDKGTEGWESA 661

Query: 328 SSKDFDGNGVGDSSA-----RNGFENSSGISE--DSGVILGSSDQHEVELSRTGGNRKRS 380
           +++  +  G GD+ +     ++G+   S  +E  D     G +D      S  GG R   
Sbjct: 662 ATQTKNSGGWGDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE 721

Query: 381 SDPDEAGNLSPGSDVSDSGGNT----WSSDSGSGGGGKSADEL--------------GVG 422
             P  + N +P  D    GG      WS  SG  G G+  D+               G G
Sbjct: 722 KTP-SSWNENPSKDQGWGGGRQPNQGWS--SGKNGWGEEVDQTKNSNWESSASKPVSGWG 778

Query: 423 ASGLNEFGETGLSG-----SEKGSHIPEATPKYSET 453
             G NE G  G  G     S+ G    + +P ++ET
Sbjct: 779 EGGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNET 814



>gi|60688059|gb|AAH45620.2|   NUP214 protein [Homo sapiens]
          Length = 2090

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 94/387 (24%), Positives = 136/387 (35%), Gaps = 74/387 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1714 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1770

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1771 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1826

Query: 139  SDKKKPLFSF----EFGATGEDEDKSRERWDAG-----NSRSEDSPAVGTGSSGLKLGAG 189
            +      FSF     FG++       +     G      S S      G+G++G   G  
Sbjct: 1827 TTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGNVFGSGNTGRGGGFF 1886

Query: 190  KG-------DAA-----------FGFEVSD--SNSFGDTGISSKTVEGNQTSS------- 222
             G       DAA           FG   +   SN FG++G  +KT  G  +SS       
Sbjct: 1887 SGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSG--AKTFGGFASSSFGEQKPT 1944

Query: 223  ---SGGSVSIDLGDTSFRSENQFVGGGSLNSI-SNLWDSGQEGFG-----------INEI 267
               S G  S+      F S N+  G G+     S     G  GFG            + +
Sbjct: 1945 GTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPL 2004

Query: 268  GGNG----MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSG 323
            G  G      G+ +A AG  GFGS S+++        FG   ++    F    S S Q+ 
Sbjct: 2005 GSTGGKVFGEGTAAASAGGFGFGSSSNTT-------SFGTLASQNAPTFG---SLSQQTS 2054

Query: 324  DNGNSSKDFDGNGVGDSSARNGFENSS 350
              G  S  F G G G      G  NSS
Sbjct: 2055 GFGTQSSGFSGFGSGTGGFSFGSNNSS 2081



>gi|2654425|gb|AAB87728.1|   dentin matrix protein 1
          Length = 497

 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 109/480 (22%), Positives = 170/480 (35%), Gaps = 67/480 (13%)

Query: 31  YGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSS 85
           Y ++ S D +  K   +     P   ED S   Q      S+D       AGGF  S+  
Sbjct: 22  YQNNESEDSEEWKGHLAQAPTPPLANEDPSDCTQSEEGLGSDDHQYIYRLAGGFSRSTGK 81

Query: 86  SGDS------DRTKPFFSLGLGAPGKAEDKSGDSQDAGGSK--------SEDTPPGGFFY 131
            GD       D     F      PG  + + G +   G  +        SE++ P G   
Sbjct: 82  GGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDS 141

Query: 132 GSSSSGDS---DKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGA 188
              ++ +S   D +  + S   G     E +S E W  G S  E S              
Sbjct: 142 AQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESS-------------- 187

Query: 189 GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSL 248
             GD   G E+ D     D   S ++  GN   +S G  S + G+ S ++  Q  GG  L
Sbjct: 188 -HGD---GSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQL 243

Query: 249 NSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                L    ++ F  + I        +      +   SDS+   E S   + GL + + 
Sbjct: 244 -----LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST---ENSNSRDTGLSQPR- 294

Query: 309 GAEFNFRDS-GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHE 367
                 RDS G +Q     N S++   N  G SS  +   N S   E+S     S  Q E
Sbjct: 295 ------RDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSS-QENS-----SESQEE 342

Query: 368 VELSRTGGNRKRSSD--PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
           V     G N   ++    D+  + S   D S +  ++ S         +S++ L      
Sbjct: 343 VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 402

Query: 426 LNEFGETGLSGSEKG--SHIPEATPKYSETNAIIGQDINEHIANSKIPGDCPNAVGKSYE 483
             E  E   S S++G  SH   A  +  E+++      ++  + SK   +   +   S E
Sbjct: 403 -PESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEE 461



>gi|4758172|ref|NP_004398.1|   dentin matrix acidic phosphoprotein [Homo sapiens]
 gi|2138321|gb|AAC51332.1|   dentin matrix acidic phosphoprotein 1 [Homo sapiens]
 gi|7673998|sp|Q13316|DMP1_HUMAN   Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix
           protein-1) (DMP-1)
          Length = 513

 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 102/435 (23%), Positives = 159/435 (36%), Gaps = 60/435 (13%)

Query: 60  SRQRQDAGSPKSEDTPAGG---FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDK---SGDS 113
           SR     G  K +D    G   F +  S  G  DR +   S  LG+   ++D    S +S
Sbjct: 92  SRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSR-LGSDEDSDDTIQASEES 150

Query: 114 QDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
              G   ++DT        +S S + D +  + S   G     E +S E W  G S  E 
Sbjct: 151 APQGQDSAQDT--------TSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGES 202

Query: 174 SPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGD 233
           S                GD   G E+ D     D   S ++  GN   +S G  S + G+
Sbjct: 203 S---------------HGD---GSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGE 244

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSV 293
            S ++  Q  GG  L     L    ++ F  + I        +      +   SDS+   
Sbjct: 245 NSEQANTQDSGGSQL-----LEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDST--- 296

Query: 294 EKSWLFEFGLGETKGGAEFNFRDS-GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGI 352
           E S   + GL + +       RDS G +Q     N S++   N  G SS  +   N S  
Sbjct: 297 ENSNSRDTGLSQPR-------RDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSS- 348

Query: 353 SEDSGVILGSSDQHEVELSRTGGNRKRSSD--PDEAGNLSPGSDVSDSGGNTWSSDSGSG 410
            E+S     S  Q EV     G N   ++    D+  + S   D S +  ++ S      
Sbjct: 349 QENS-----SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQ 403

Query: 411 GGGKSADELGVGASGLNEFGETGLSGSEKG--SHIPEATPKYSETNAIIGQDINEHIANS 468
              +S++ L        E  E   S S++G  SH   A  +  E+++      ++  + S
Sbjct: 404 ADSESSESLNFSEES-PESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRS 462

Query: 469 KIPGDCPNAVGKSYE 483
           K   +   +   S E
Sbjct: 463 KEDSNSTESKSSSEE 477



>gi|18490128|gb|AAH22258.1|   VWF protein [Homo sapiens]
          Length = 273

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 26/63 (41%), Positives = 34/63 (53%), Gaps = 6/63 (9%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNP-- 689
           V +    F  T GLCG++N  AEDDFM+ +  L      FANSW + S    C + +P  
Sbjct: 185 VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPS 244

Query: 690 SSC 692
           SSC
Sbjct: 245 SSC 247



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 24/70 (34%), Positives = 34/70 (48%)

Query: 940  GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGA 999
            G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+  ++ S  
Sbjct: 162  GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDP 221

Query: 1000 LEFGNSWKTS 1009
             +F NSW  S
Sbjct: 222  YDFANSWALS 231



>gi|28958131|gb|AAH47455.1|   DDX4 protein [Homo sapiens]
          Length = 690

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 54/161 (33%), Positives = 70/161 (43%), Gaps = 23/161 (14%)

Query: 309 GAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISED-SGVILGSSDQHE 367
           G  F  RD+G     DN ++   F   GVG S    GF NS     D SG    SS+  E
Sbjct: 62  GRNFGNRDAGECNKRDNTSTMGGF---GVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCE 118

Query: 368 VELSRTGGNRKRSS---DPDEAGNLSPG------SDVSDSG-GNTWSSDSGSG---GGGK 414
              +R  G  KR     DPDE    + G        +S +G G+T  S SGSG   GG K
Sbjct: 119 DNPTRNRGFSKRGDNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTSQSRSGSGSERGGYK 178

Query: 415 SADELGVGASGLN------EFGETGLSGSEKGSHIPEATPK 449
             +E  +  SG N      E GE+  +   K ++IP   P+
Sbjct: 179 GLNEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPPE 219



>gi|31874060|emb|CAD97946.1|   hypothetical protein [Homo sapiens]
          Length = 1519

 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 96/437 (21%), Positives = 140/437 (32%), Gaps = 85/437 (19%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1143 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1199

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1200 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1255

Query: 139  SDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFE 198
            +      FSF                         +   G+G++G               
Sbjct: 1256 TTAATSGFSF-----------------------CQASGFGSGNTG--------------- 1277

Query: 199  VSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSI------- 251
                + FG    +   V G Q+SSS GSV        F S N   GGG  + +       
Sbjct: 1278 ----SVFGQAASTGGIVFGQQSSSSSGSV--------FGSGNTGRGGGFFSGLGGKPSQD 1325

Query: 252  ---SNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                N + S   GFG             S    F GF S S    + +  F  G G    
Sbjct: 1326 AANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSV-- 1383

Query: 309  GAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEV 368
             A   F  S  N++G  G +         G      G     G+        GS+     
Sbjct: 1384 -ASQGFGFSSPNKTGGFGAAPV------FGSPPTFGGSPGFGGVP-----AFGSAPAFTS 1431

Query: 369  ELSRTGGN-RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVG--ASG 425
             L  TGG      +    AG    GS  + +   T +S +    G  S    G G  +SG
Sbjct: 1432 PLGSTGGKVFGEGTAAASAGGFGFGSSGNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSG 1491

Query: 426  LNEFGETGLSGSEKGSH 442
             + FG +G  G   GS+
Sbjct: 1492 FSGFG-SGTGGFSFGSN 1507



>gi|37181949|gb|AAQ88778.1|   KFQG729 [Homo sapiens]
          Length = 440

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 75/304 (24%), Positives = 118/304 (38%), Gaps = 41/304 (13%)

Query: 152 ATGEDEDKSRERWDAGNSRSEDSPAVGTGS-----SGLKLGAGKGDA-AFGFEVSDS-NS 204
           A  E   K+  +   G + S+ S A+G G+     +G++   G G A A G  V ++ ++
Sbjct: 46  ALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHA 105

Query: 205 FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGI 264
            G+TG       G Q         I  G  + R   Q V G S       W++       
Sbjct: 106 LGNTGHEI----GRQAEDV-----IRHGADAVRGSWQGVPGHS-----GAWETS------ 145

Query: 265 NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD 324
              GG+G+ GS   + G  G G  +   +   W+  +  G + G    N + +   Q G+
Sbjct: 146 ---GGHGIFGS---QGGLGGQGQGNPGGLGTPWVHGYP-GNSAGSFGMNPQGAPWGQGGN 198

Query: 325 NG------NSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRK 378
            G      N+       G G   A N  E  +     SG   GSS+      S++G +  
Sbjct: 199 GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTN-PPPSGSGGGSSNSGGGSGSQSGSSGS 257

Query: 379 RSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSE 438
            S+  +  G+ S GS    S G++    SG   GG S +  G      +E      +GS 
Sbjct: 258 GSNGDNNNGSSSGGSSSGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 317

Query: 439 KGSH 442
            G+H
Sbjct: 318 SGNH 321



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 71/278 (25%), Positives = 101/278 (36%), Gaps = 57/278 (20%)

Query: 64  QDAGSPKSEDTP--AGGFFNSSSSSGDSDRTKPFFSLGLGAPGK-------AEDKSGDSQ 114
           Q  G+P    TP   G   NS+ S G + +  P+   G G P         A  + G   
Sbjct: 160 QGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGS 219

Query: 115 DAGGSKSE---DTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRS 171
               +++E   + PP G   GSS+SG     +   S     +G + D +      G+S  
Sbjct: 220 VRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSS----GSGSNGDNNNGSSSGGSSSG 275

Query: 172 EDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL 231
             S +   GSSG   G   G++  G    DS S    G S+ +  GN   S GG      
Sbjct: 276 SSSGSSSGGSSGGSSGGSSGNS--GGSRGDSGSESSWGSSTGSSSGNHGGSGGG------ 327

Query: 232 GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG-SDSS 290
                                N    G E  G NE  G+G SG      GF+G G S + 
Sbjct: 328 ---------------------NGHKPGCEKPG-NEARGSGESGI----QGFRGQGVSSNM 361

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 328
             + K            GG+  N+R  GS+     G++
Sbjct: 362 REISKEG------NRLLGGSGDNYRGQGSSWGSGGGDA 393



>gi|21757162|dbj|BAC05041.1|   unnamed protein product [Homo sapiens]
          Length = 455

 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 76/353 (21%), Positives = 113/353 (32%), Gaps = 38/353 (10%)

Query: 54  GETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSL--------GLGAPGK 105
           G T+ K ++     +P  E T +GG  +   +  +  + K    +        G  A G 
Sbjct: 43  GATDTKKKKINHGTNP--ETTTSGGCHSPEDTQQNRAQLKEEKKMREQEDVETGGEAAGA 100

Query: 106 AEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWD 165
            E   G   +  GS +ED  PGG   G+     ++  +   + +  A GED        D
Sbjct: 101 GEADVGAGGEDAGSGAEDVGPGGEDVGAGREAAAEGGENAGAEDVAAGGEDAGGEE---D 157

Query: 166 AGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG 225
           AG    +  P       G   GAG+ DA  G +        D G   +     +  +  G
Sbjct: 158 AGAGEEDMGPG-EDARGGEHAGAGEEDAGGGGD--------DAGAGGEDAGAGRKDAGAG 208

Query: 226 SVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGF 285
              +  G     +  + VG               E  G  E  G G       E    G 
Sbjct: 209 GGDVGAGGEDVGAGREDVGAAEATGTEG------EAVGTREDAGAGEDMGAGGEDAGPG- 261

Query: 286 GSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS-SKDFDGNGVGDSSARN 344
           G D+    E     + G G    GA      +G    G  G       +  G G      
Sbjct: 262 GEDAGPGGE-----DAGAGGEDAGAGGEDVGAGGEDVGAGGEDVGPGGEDVGAGGEDVGP 316

Query: 345 GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSD 397
           G E++ G     G   G   +      R GG R+R    +E    + G D  D
Sbjct: 317 GGEDAGGRRRRCG---GRRRRCGARRRRCGGRRRRCGGQEEKMRGAGGEDAGD 366



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 22/213 (10%)

Query: 243 VGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFG 302
           VG G  ++ S   D G  G  +         G  +A A     G + +   E +   E  
Sbjct: 105 VGAGGEDAGSGAEDVGPGGEDVGAGREAAAEGGENAGAEDVAAGGEDAGGEEDAGAGEED 164

Query: 303 LG---ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVI 359
           +G   + +GG      +  +   GD+  +  +  G G  D+ A  G   + G  ED G  
Sbjct: 165 MGPGEDARGGEHAGAGEEDAGGGGDDAGAGGEDAGAGRKDAGAGGGDVGAGG--EDVGA- 221

Query: 360 LGSSDQHEVELSRTGGNRKRSSDPDEAG--------NLSPGSDVSDSGGNTWSSDSGSGG 411
            G  D    E + T G    + +   AG        +  PG + +  GG     D+G+GG
Sbjct: 222 -GREDVGAAEATGTEGEAVGTREDAGAGEDMGAGGEDAGPGGEDAGPGGE----DAGAGG 276

Query: 412 --GGKSADELGVGASGLNEFGE-TGLSGSEKGS 441
              G   +++G G   +   GE  G  G + G+
Sbjct: 277 EDAGAGGEDVGAGGEDVGAGGEDVGPGGEDVGA 309



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 56/239 (23%), Positives = 93/239 (38%), Gaps = 27/239 (11%)

Query: 215 VEGNQTSSSGGSVSIDLG--DTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEI--GGN 270
           VE    ++  G   +  G  D    +E+   GG  + +       G E  G  ++  GG 
Sbjct: 91  VETGGEAAGAGEADVGAGGEDAGSGAEDVGPGGEDVGAGREAAAEGGENAGAEDVAAGGE 150

Query: 271 GMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              G   A AG +  G    +   +      G GE   G   +  D+G+   G++  + +
Sbjct: 151 DAGGEEDAGAGEEDMGPGEDARGGE----HAGAGEEDAGGGGD--DAGAG--GEDAGAGR 202

Query: 331 DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSR--TGGNRKRSSDPDEAG- 387
              G G GD  A  G E+     ED G    +  + E   +R   G      +  ++AG 
Sbjct: 203 KDAGAGGGDVGA--GGEDVGAGREDVGAAEATGTEGEAVGTREDAGAGEDMGAGGEDAGP 260

Query: 388 ---NLSPGSDVSDSGGNTWSSDSGSGGG--GKSADELGVGASGLNEFGE-TGLSGSEKG 440
              +  PG + + +GG     D+G+GG   G   +++G G   +   GE  G  G + G
Sbjct: 261 GGEDAGPGGEDAGAGGE----DAGAGGEDVGAGGEDVGAGGEDVGPGGEDVGAGGEDVG 315



>gi|3077806|dbj|BAA25794.1|   loricrin [Homo sapiens]
          Length = 338

 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 55/186 (29%), Positives = 60/186 (32%), Gaps = 7/186 (3%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G G  G   G G G  + G   S     G  G S     G  +   GG      G  S  
Sbjct: 30  GGGGCGFFGGGGSGGGSSG---SGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGG 86

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS    S  + SG  G G    GG G SG  S      G GS        S 
Sbjct: 87  SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGG----SG 142

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
            F  G G   G A       G +  G +G  S  F   G G S        S G S   G
Sbjct: 143 CFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGGGSGCGG 202

Query: 358 VILGSS 363
              G S
Sbjct: 203 GSSGGS 208



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 49/169 (28%), Positives = 55/169 (32%), Gaps = 37/169 (21%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG G  G+     GF G G     S      +  G G + GG        G   SG  G 
Sbjct: 22  GGGGGGGTGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGC-------GGGSSGGGGG 74

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
                 G G G S   +G   SSG                      GG+   SS    +G
Sbjct: 75  GGIGGCGGGSGGSVKYSGGGGSSG----------------------GGSGCFSSGGGGSG 112

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
             S G   S  GG   S    SGGGG S      G SG    G  G SG
Sbjct: 113 CFSSGGGGSSGGG---SGCFSSGGGGSSG-----GGSGCFSSGGGGFSG 153



>gi|47132620|ref|NP_000414.2|   keratin 2a [Homo sapiens]
          Length = 639

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 32/174 (18%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLF--EFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           MSG +S+        S  SS+V     F    G G + GG       SGS+  G  G  S
Sbjct: 491 MSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGY----SSGSSSYGSGGRQS 546

Query: 330 KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
               G+G G S +  G+ +  G                       G R  S    + G++
Sbjct: 547 GSRGGSGGGGSISGGGYGSGGG----------------------SGGRYGSGGGSKGGSI 584

Query: 390 SPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHI 443
           S G     SGG   SS  GS GG  S    G G  G +     G SG   GS +
Sbjct: 585 SGGG--YGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSV--KGSSGEAFGSSV 634



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 46/159 (28%), Positives = 61/159 (38%), Gaps = 27/159 (16%)

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTV---EGNQTSSSGG-----SVSIDLGDTSFRSENQF 242
           GD +    VS ++S   + ++SK      G + SSSGG     S S   G     S    
Sbjct: 493 GDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 552

Query: 243 VGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFG 302
            GGGS++     + SG    G    GG    GS+S      G G  SS            
Sbjct: 553 GGGGSISGGG--YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSG----------- 599

Query: 303 LGETKGGAEFNFRDSGSNQSGDNGNSS-KDFDGNGVGDS 340
            G ++GG+       G   SG  G+SS K   G   G S
Sbjct: 600 -GGSRGGSS----SGGGYGSGGGGSSSVKGSSGEAFGSS 633



>gi|190406|gb|AAA36487.1|   profilaggrin
          Length = 1218

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 45/422 (10%)

Query: 23   ASRSGGFSYGSSSSGDLDRKK-PLFSLEFGSPGETEDKSRQ----------------RQD 65
            +SR      G SS     R +   FS +  S  ++ED  R+                R  
Sbjct: 597  SSRHSQVGQGESSGSRTSRNQGSSFSQDRDSQAQSEDSERRSASGSRNHRGSAQEQSRDG 656

Query: 66   AGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPG---KAEDKSGDSQDAGGSKSE 122
            +  P S      G   S+ SS  S       S G  A     +A   +G+   +G  +S 
Sbjct: 657  SRHPGSHQEDRAGHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGHQQSA 716

Query: 123  DTPP-GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
            D+    G  +G +SS   D     +S    +  E   ++ +       R   S       
Sbjct: 717  DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQE 776

Query: 182  S--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDLGDTSF 236
            S  G   G      +F ++VS       T   S++  G    S+    GS      D+S 
Sbjct: 777  STRGQSRGRSGRSGSFLYQVS-------THEQSESAHGRSAPSTRRRQGSHHDQARDSSR 829

Query: 237  RSENQFVGGGSLNSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKG-----FGSDSS 290
             S +Q  G  ++         G++G    + +  +G SGS  +    +G      G+  S
Sbjct: 830  HSASQ-EGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASHGTSGS 888

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
             S  +    E   G+  G          ++   D+   S+   G   G  ++RN     S
Sbjct: 889  RSASRQTRDEEQSGD--GTRHSGSHHQEASTQADSSRHSQVGQGQSAGSRTSRN---QGS 943

Query: 351  GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSG 410
             +S+D      S D      S +  +R  + +    G+  PGS   D  G+  S+DS S 
Sbjct: 944  SVSQDRDSEGQSEDSERHSGSASRNHRGSAQEQSRDGSRHPGSHDEDRAGHRQSADSSSQ 1003

Query: 411  GG 412
             G
Sbjct: 1004 SG 1005



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 89/395 (22%), Positives = 145/395 (36%), Gaps = 26/395 (6%)

Query: 61  RQRQDAGSPKSEDTPAGGFFNSSSSSGDSD-RTKPFFSLGLGAPGKAEDKSGDSQDAGG- 118
           + R  +  P+S D       +S+ SS  S  R     S G  A    + +S   +  G  
Sbjct: 328 QSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSAGERHGSH 387

Query: 119 --SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPA 176
               ++ +   G  +G +S+  SD     +     +  E   +  +       R   S  
Sbjct: 388 HQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQASDNEGHSEDSDSQSVAGQRQARSRH 447

Query: 177 VGTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDL 231
                S  G   G      +F ++VS       T   S++  G   +S+G   GS     
Sbjct: 448 QSHQESTRGRSRGGSGRSGSFLYQVS-------THEQSESSHGWARTSTGRRQGSRHDQA 500

Query: 232 GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGN-GMSGSVSAEAGFKGFGSDSS 290
            D+S  S +Q  G  ++++       G+ G+   +   + G SGS  +    +G  SD+S
Sbjct: 501 QDSSRHSTSQ-QGQDTIHAHPGSRRGGRHGYHHEQSADSTGHSGSQHSHTTTQG-RSDAS 558

Query: 291 --SSVEKSWLFEFGLGETKGGAEFNFRDSGSN-QSGDNGNSSKDFDGNGVGDSS-ARNGF 346
             SS  +S   E    E  G      R SGS+ Q       S      G G+SS +R   
Sbjct: 559 RGSSGSRSTSRETRDQEQSGDGS---RHSGSHHQEASTRAESSRHSQVGQGESSGSRTSR 615

Query: 347 ENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSD 406
              S  S+D      S D      S +  +R  + +    G+  PGS   D  G+  S++
Sbjct: 616 NQGSSFSQDRDSQAQSEDSERRSASGSRNHRGSAQEQSRDGSRHPGSHQEDRAGHRQSAE 675

Query: 407 SGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           S S  G   A+    G +  ++      +G   GS
Sbjct: 676 SSSQSGTHHAENSSGGQAASSQEQARSSAGERHGS 710



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 76/337 (22%), Positives = 120/337 (35%), Gaps = 31/337 (9%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSR--QRQDAGSPKSEDTPA 76
            G  +ASR    +     SGD  R       E  +  ++   S+  Q Q AGS  S +  +
Sbjct: 887  GSRSASRQ---TRDEEQSGDGTRHSGSHHQEASTQADSSRHSQVGQGQSAGSRTSRNQGS 943

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
                +  S     D  +   S      G A+++S D     GS  ED   G      SSS
Sbjct: 944  SVSQDRDSEGQSEDSERHSGSASRNHRGSAQEQSRDGSRHPGSHDEDRA-GHRQSADSSS 1002

Query: 137  GDSDKKKPLFSFEFGATGEDEDKSR--ERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
                +     S    A+ +++ +SR  +R  +G+ +S DS      S    +G G+  +A
Sbjct: 1003 QSGTRHTQTSSRRQAASSQEQARSRAGDRHGSGHQQSADS------SRHSAIGRGQASSA 1056

Query: 195  FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG----------DTSFRSENQFVG 244
                V D    G  G  +   EG+   S   SVS               T  RS+ +   
Sbjct: 1057 ----VRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQESTRGRSQGRSGR 1112

Query: 245  GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLG 304
             GS     +  +  +   G          GS   +A      S  S+S E         G
Sbjct: 1113 SGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS---SRHSASQEGQDTIRAHPG 1169

Query: 305  ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
              +GG + +  +   ++SG +G+        G  D+S
Sbjct: 1170 SRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1206



>gi|181402|gb|AAC83410.1|   epidermal cytokeratin 2 [Homo sapiens]
 gi|2565257|gb|AAB81946.1|   keratin 2e [Homo sapiens]
 gi|482387|pir||A44861   keratin, 67K type II epidermal - human
 gi|547754|sp|P35908|K22E_HUMAN   Keratin, type II cytoskeletal 2 epidermal (Cytokeratin 2e) (K2e)
           (CK 2e)
          Length = 645

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 32/174 (18%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLF--EFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           MSG +S+        S  SS+V     F    G G + GG       SGS+  G  G  S
Sbjct: 497 MSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGY----SSGSSSYGSGGRQS 552

Query: 330 KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
               G+G G S +  G+ +  G                       G R  S    + G++
Sbjct: 553 GSRGGSGGGGSISGGGYGSGGG----------------------SGGRYGSGGGSKGGSI 590

Query: 390 SPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHI 443
           S G     SGG   SS  GS GG  S    G G  G +     G SG   GS +
Sbjct: 591 SGGG--YGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSV--KGSSGEAFGSSV 640



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 46/159 (28%), Positives = 61/159 (38%), Gaps = 27/159 (16%)

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTV---EGNQTSSSGG-----SVSIDLGDTSFRSENQF 242
           GD +    VS ++S   + ++SK      G + SSSGG     S S   G     S    
Sbjct: 499 GDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGS 558

Query: 243 VGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFG 302
            GGGS++     + SG    G    GG    GS+S      G G  SS            
Sbjct: 559 GGGGSISGGG--YGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSG----------- 605

Query: 303 LGETKGGAEFNFRDSGSNQSGDNGNSS-KDFDGNGVGDS 340
            G ++GG+       G   SG  G+SS K   G   G S
Sbjct: 606 -GGSRGGSS----SGGGYGSGGGGSSSVKGSSGEAFGSS 639



>gi|190396|gb|AAA63244.1|   profilaggrin
          Length = 990

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 91/422 (21%), Positives = 147/422 (34%), Gaps = 45/422 (10%)

Query: 23  ASRSGGFSYGSSSSGDLDRKK-PLFSLEFGSPGETEDKSRQ----------------RQD 65
           +SR      G SS     R +   FS +  S  ++ED  R+                R  
Sbjct: 375 SSRHSQVGQGESSGSRTSRNQGSSFSQDRDSQAQSEDSERRSASASRNHRGSAQEQSRDG 434

Query: 66  AGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPG---KAEDKSGDSQDAGGSKSE 122
           +  P S      G   S+ SS  S       S G  A     +A   +G+   +G  +S 
Sbjct: 435 SRHPGSHQEDRAGHRQSAESSSQSGTHHAENSSGGQAASSQEQARSSAGERHGSGHQQSA 494

Query: 123 DTPP-GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
           D+    G  +G +SS   D     +S    +  E   ++ +       R   S       
Sbjct: 495 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDQEGHSENSDSQSVSGQRQARSHQQSHQE 554

Query: 182 S--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDLGDTSF 236
           S  G   G      +F ++VS       T   S++  G    S+    GS      D+S 
Sbjct: 555 STRGQSRGRSGRSGSFLYQVS-------THEQSESAHGRSAPSTRRRQGSHHDQARDSSR 607

Query: 237 RSENQFVGGGSLNSISNLWDSGQEGFGINE-IGGNGMSGSVSAEAGFKG-----FGSDSS 290
            S +Q  G  ++         G++G    + +  +G SGS  +    +G      G+  S
Sbjct: 608 HSASQ-EGQDTIRGHPGSSRGGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASHGTSGS 666

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
            S  +    E   G+  G          ++   D+   S+   G   G  ++RN     S
Sbjct: 667 RSASRQTRDEEQSGD--GTRHSGSHHQEASTQADSSRHSQVGQGQSAGSRTSRN---QGS 721

Query: 351 GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSG 410
            +S+D      S D      S +  +R  + +    G+  PGS   D  G+  S+DS S 
Sbjct: 722 SVSQDRDSEGQSEDSERHSGSASRNHRGSAQEQSRDGSRHPGSHDEDRAGHRQSADSSSQ 781

Query: 411 GG 412
            G
Sbjct: 782 SG 783



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 89/395 (22%), Positives = 145/395 (36%), Gaps = 26/395 (6%)

Query: 61  RQRQDAGSPKSEDTPAGGFFNSSSSSGDSD-RTKPFFSLGLGAPGKAEDKSGDSQDAGG- 118
           + R  +  P+S D       +S+ SS  S  R     S G  A    + +S   +  G  
Sbjct: 106 QSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSAGERHGSH 165

Query: 119 --SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPA 176
               ++ +   G  +G +S+  SD     +     +  E   +  +       R   S  
Sbjct: 166 HQQSADSSRHSGIGHGQASTAVSDSGHRGYRGSQASDNEGHSEDSDSQSVAGQRQARSRH 225

Query: 177 VGTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDL 231
                S  G   G      +F ++VS       T   S++  G   +S+G   GS     
Sbjct: 226 QSHQESTRGRSRGGSGRSGSFLYQVS-------THEQSESSHGWARTSTGRRQGSRHDQA 278

Query: 232 GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGN-GMSGSVSAEAGFKGFGSDSS 290
            D+S  S +Q  G  ++++       G+ G+   +   + G SGS  +    +G  SD+S
Sbjct: 279 QDSSRHSTSQ-QGQDTIHAHPGSRRGGRHGYHHEQSADSTGHSGSQHSHTTTQG-RSDAS 336

Query: 291 --SSVEKSWLFEFGLGETKGGAEFNFRDSGSN-QSGDNGNSSKDFDGNGVGDSS-ARNGF 346
             SS  +S   E    E  G      R SGS+ Q       S      G G+SS +R   
Sbjct: 337 RGSSGSRSTSRETRDQEQSGDGS---RHSGSHHQEASTRAESSRHSQVGQGESSGSRTSR 393

Query: 347 ENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSD 406
              S  S+D      S D      S +  +R  + +    G+  PGS   D  G+  S++
Sbjct: 394 NQGSSFSQDRDSQAQSEDSERRSASASRNHRGSAQEQSRDGSRHPGSHQEDRAGHRQSAE 453

Query: 407 SGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           S S  G   A+    G +  ++      +G   GS
Sbjct: 454 SSSQSGTHHAENSSGGQAASSQEQARSSAGERHGS 488



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 76/337 (22%), Positives = 120/337 (35%), Gaps = 31/337 (9%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSR--QRQDAGSPKSEDTPA 76
           G  +ASR    +     SGD  R       E  +  ++   S+  Q Q AGS  S +  +
Sbjct: 665 GSRSASRQ---TRDEEQSGDGTRHSGSHHQEASTQADSSRHSQVGQGQSAGSRTSRNQGS 721

Query: 77  GGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS 136
               +  S     D  +   S      G A+++S D     GS  ED   G      SSS
Sbjct: 722 SVSQDRDSEGQSEDSERHSGSASRNHRGSAQEQSRDGSRHPGSHDEDRA-GHRQSADSSS 780

Query: 137 GDSDKKKPLFSFEFGATGEDEDKSR--ERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAA 194
               +     S    A+ +++ +SR  +R  +G+ +S DS      S    +G G+  +A
Sbjct: 781 QSGTRHTQTSSRRQAASSQEQARSRAGDRHGSGHQQSADS------SRHSAIGRGQASSA 834

Query: 195 FGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG----------DTSFRSENQFVG 244
               V D    G  G  +   EG+   S   SVS               T  RS+ +   
Sbjct: 835 ----VRDRGHRGSRGSQASDQEGHSEDSDSQSVSAQRQAGSHQQSHQESTRGRSQGRSGR 890

Query: 245 GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLG 304
            GS     +  +  +   G          GS   +A      S  S+S E         G
Sbjct: 891 SGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS---SRHSASQEGQDTIRAHPG 947

Query: 305 ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
             +GG + +  +   ++SG +G+        G  D+S
Sbjct: 948 SRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 984



>gi|631466|pir||A53767   mucin MUC5B, tracheobronchial - human
 gi|488073|gb|AAA18431.1|   tracheobronchial mucin
          Length = 1056

 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 31/149 (20%), Positives = 53/149 (35%), Gaps = 30/149 (20%)

Query: 975  GLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTS----QECS----------------- 1013
            G CG    D KD+  T   +V +   E    W  S      C                  
Sbjct: 447  GQCGTCTNDRKDECRTPRGTVVASCSEMSGLWNVSIPDQPACHRPHPTPTTVGPTTVGST 506

Query: 1014 ----DTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC-ACD 1068
                 TV  T    + P         C ++    F  CH  + P  +++ C+ + C   D
Sbjct: 507  TVGPTTVGSTTVGPTTPPAPCLPSPICHLILSKVFEPCHTVIPPLLFYEGCVFDRCHMTD 566

Query: 1069 MEGKYLGFCTAVAMYAEACSAVGVCVSWR 1097
            ++      C+++ +YA  C++  +C+ WR
Sbjct: 567  LDV----VCSSLELYARLCASHDICIDWR 591



>gi|7440064|pir||G02127   fus-like protein - human (fragment)
 gi|1040970|gb|AAA79948.1|   fus-like protein
          Length = 528

 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 67/274 (24%), Positives = 99/274 (36%), Gaps = 37/274 (13%)

Query: 203 NSFGDTGISSKTVEGNQTS-----SSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDS 257
           +S+   G S  T  G Q++     S+GG  S     +S+  ++ + G G   + S+   S
Sbjct: 52  SSYSSYGQSQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGPQPTPSST--S 109

Query: 258 GQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
           G  G   ++    G   S   +  +   G    S  ++      G G+     ++N   S
Sbjct: 110 GSYGSS-SQTSSYGQPPSYGQQPSY---GGQQQSYGQQQSYNPSGYGQQN---QYNSSSS 162

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS---GISEDSGVILGSSDQHEVELSRTG 374
           GS   G  G       G+G G      G        G  + SG   G   Q +    R G
Sbjct: 163 GSGGGGSYGQDQSSMSGSGGGGGGGGGGGSGGGGGYGNQDQSGGGGGGYGQQD----RGG 218

Query: 375 GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS---GLNEFGE 431
             R RSS     G    G   + S G       G G GG+     G+G S   G N+FG 
Sbjct: 219 RGRGRSS----GGGGGSGGGYNRSSGGYEPRGRGGGRGGRG----GMGGSDRGGFNKFGG 270

Query: 432 TGLSGSEKGSHIPEATPKYSETNAIIGQDINEHI 465
               GS   S         S+ N I  Q + E++
Sbjct: 271 PRDQGSRHDSE-----QDNSDNNTIFVQGLGENV 299



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 89/410 (21%), Positives = 137/410 (33%), Gaps = 66/410 (16%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRT--------KPFFSLG-LGAPGKAEDKSGDSQ 114
           Q + S  S+ T  G   +S SS G S  T        + + S G  G+   ++   G   
Sbjct: 35  QQSYSGYSQSTDTGYGQSSYSSYGQSQNTGYGTQSAPQGYGSTGGYGSSQSSQSSYGQQS 94

Query: 115 DAGGSKSEDTPPG-GFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSED 173
              G   + TP      YGSSS   S  + P +       G+      ++   G  +S +
Sbjct: 95  SYPGYGPQPTPSSTSGSYGSSSQTSSYGQPPSY-------GQQPSYGGQQQSYGQQQSYN 147

Query: 174 SPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGD 233
               G  +      +G G              G  G    ++ G+     GG      G 
Sbjct: 148 PSGYGQQNQYNSSSSGSGGG------------GSYGQDQSSMSGSGGGGGGGGGGGSGGG 195

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF---KGFGSDSS 290
             + +++Q  GGG         D G  G G +  GG G  G  +  +G    +G G    
Sbjct: 196 GGYGNQDQSGGGGGGYGQQ---DRGGRGRGRSSGGGGGSGGGYNRSSGGYEPRGRGGGRG 252

Query: 291 SSVEKSWLFEFGLGETKGGAEFNF---RDSGSNQSGDNGNSSKD-FDGNGVGDSSARNGF 346
                      G+G +  G    F   RD GS    +  NS  +     G+G++      
Sbjct: 253 G--------RGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVT---I 301

Query: 347 ENSSGISEDSGVILGS--SDQHEVEL--SRTGGNRKRSS-----DPDEAGNLSPGSDVSD 397
           E+ +   +  G+I  +  + Q  + L   R  G  K  +     DP  A       D  +
Sbjct: 302 ESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKE 361

Query: 398 SGGN-------TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
             GN       T  +D   GGG         G  G   +G  G  G  +G
Sbjct: 362 FSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGGRG 411



>gi|223918|prf||1004351A   fibrinogen alphaA
          Length = 462

 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 72/286 (25%), Positives = 106/286 (37%), Gaps = 31/286 (10%)

Query: 47  SLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKA 106
           S  +G+  ETE          SP++  + AG + + SS  G +    P  S   G  G A
Sbjct: 203 STSYGTGSETE----------SPRNPSS-AGSWNSGSSGPGSTGNRNPGSS---GTGGTA 248

Query: 107 EDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDA 166
             K G S             G +  GSS +G +  + P  S   G+TG     S ER  A
Sbjct: 249 TWKPGSSGPGSX--------GSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNPGSSERGSA 299

Query: 167 GNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT--GISSKTVEGNQTSSSG 224
           G+  SE S +  TG    + G+ + D+        +N    T   +S     G +     
Sbjct: 300 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 359

Query: 225 GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
             +    GD   R+  + V  GS  +      S  +      IG +G    V+ E     
Sbjct: 360 EKLVTSKGDKELRTGKEKVTSGSTTTTRR---SCSKTVTKTVIGPDGHK-EVTKEVVTSE 415

Query: 285 FGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSG--SNQSGDNGNS 328
            GSD   +++   L   GLGE     E    +SG  +N   D   S
Sbjct: 416 DGSDCPEAMDLGTLSGIGLGEFVSETESRGSESGIFTNTKADEAGS 461



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           +SGS+  G  GN +    G G G ++ + G   SSG         GSS         TG 
Sbjct: 225 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSXGSWNSGSSGT-----GSTGN 275

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
               S  P   G  +PGS    S G+  S  S SG  G+   E G
Sbjct: 276 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 320



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 13/141 (9%)

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T+GG+  ++      +S  N +S+  ++    G  S  N    SSG    +    GSS  
Sbjct: 199 TRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 257

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                  +G +   S+     G+  PG   S    N  SS+ GS G   S   +      
Sbjct: 258 GSXGSWNSGSSGTGSTGNQNPGSPRPG---STGTWNPGSSERGSAGHWTSESSVS----- 309

Query: 426 LNEFGETGLSGSEKGSHIPEA 446
               G TG   SE GS  P++
Sbjct: 310 ----GSTGQWHSESGSFRPDS 326



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 40/140 (28%), Positives = 56/140 (40%), Gaps = 12/140 (8%)

Query: 345 GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN-TW 403
           G E + G S   G   GS  +     S  G     SS P   GN +PGS  S +GG  TW
Sbjct: 195 GNEITRGGSTSYGT--GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGS--SGTGGTATW 250

Query: 404 ---SSDSGSGGGGKSADELGVGASGLNEFG--ETGLSGS-EKGSHIPEATPKYSETNAII 457
              SS  GS G   S    G G++G    G    G +G+   GS    +   ++  +++ 
Sbjct: 251 KPGSSGPGSXGSWNSGSS-GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 309

Query: 458 GQDINEHIANSKIPGDCPNA 477
           G     H  +     D P +
Sbjct: 310 GSTGQWHSESGSFRPDSPGS 329



>gi|34536377|dbj|BAC87623.1|   unnamed protein product [Homo sapiens]
          Length = 555

 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 59/250 (23%), Positives = 93/250 (37%), Gaps = 30/250 (12%)

Query: 209 GISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGIN--- 265
           G   K  E     + G +      D     E+   GG    S +   D G EG  +    
Sbjct: 76  GQEEKMREQEDVETGGEAAGAGEADVGAGGEDAEAGGEDAGSGAE--DVGPEGEDVGAGR 133

Query: 266 EIGGNG--MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGE-TKGGAEFNFRDSGSNQS 322
           E  G G   +G+    AG +  G +  +   +    + G GE  +GG      +  +   
Sbjct: 134 EAAGEGGENAGAEDVAAGGEDAGGEEDAGAGEE---DMGPGEDARGGEHAGAGEEDAGGG 190

Query: 323 GDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSD 382
           GD+  +  +  G G  D+ A  G   + G  ED G   G  D    E + T G    + +
Sbjct: 191 GDDAGAGGEDAGAGRKDAGAGGGDVGAGG--EDVGA--GREDVGAAEATGTEGEAVGTRE 246

Query: 383 PDEAG--------NLSPGSDVSDSGGNTWSSDSGSGG--GGKSADELGVGASGLNEFGE- 431
              AG        +  PG + +  GG     D+G+GG   G   +++G G   +   GE 
Sbjct: 247 DAGAGEDMGAGGEDAGPGGEDAGPGGE----DAGAGGEDAGAGGEDVGAGGEDVGAGGED 302

Query: 432 TGLSGSEKGS 441
            G  G + G+
Sbjct: 303 VGPGGEDVGA 312



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 42/233 (18%)

Query: 57  EDKSRQRQDAGS------PKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS 110
           ED     +DAGS      P+ ED  AG       ++G+            G    AED +
Sbjct: 106 EDAEAGGEDAGSGAEDVGPEGEDVGAG-----REAAGEG-----------GENAGAEDVA 149

Query: 111 GDSQDAGGSKS-----EDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWD 165
              +DAGG +      ED  PG    G   +G  ++       + GA GED    R+   
Sbjct: 150 AGGEDAGGEEDAGAGEEDMGPGEDARGGEHAGAGEEDAGGGGDDAGAGGEDAGAGRKDAG 209

Query: 166 AGNSRSEDSPAVGTGSSGLKLGAGKGDA----AFGFEVSDSNSFGDTGISSKTVEGNQTS 221
           AG            G+ G  +GAG+ D     A G E     +  D G       G + +
Sbjct: 210 AGGG--------DVGAGGEDVGAGREDVGAAEATGTEGEAVGTREDAGAGEDMGAGGEDA 261

Query: 222 SSGGSVSIDLG-DTSFRSENQFVGGGSLNSISNLWDSGQE--GFGINEIGGNG 271
             GG  +   G D     E+   GG  + +      +G E  G G  ++G  G
Sbjct: 262 GPGGEDAGPGGEDAGAGGEDAGAGGEDVGAGGEDVGAGGEDVGPGGEDVGAGG 314



>gi|34482047|ref|NP_004635.2|   adaptor-related protein complex 3, beta 2 subunit [Homo sapiens]
 gi|11359858|pir||T50650   AP-3 complex beta3B chain [imported] - human
 gi|2460298|gb|AAB71894.1|   AP-3 complex beta3B subunit [Homo sapiens]
 gi|18202497|sp|Q13367|A3B2_HUMAN   Adapter-related protein complex 3 beta 2 subunit (Beta3B-adaptin)
           (Adaptor protein complex AP-3 beta-2 subunit) (AP-3
           complex beta-2 subunit) (Clathrin assembly protein
           complex 3 beta-2 large chain) (Neuron-specific vesicle
           coat protein beta-NAP)
          Length = 1082

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 42/160 (26%), Positives = 61/160 (38%), Gaps = 26/160 (16%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSED 123
           ++A  P   +     +   S+     ++ KPF+S   G  G  E    D +    S S+ 
Sbjct: 646 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKS 705

Query: 124 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSG 183
           +   G    SS S + D+             EDE+K R       S SE S   G   + 
Sbjct: 706 SSESGSGESSSESDNEDQ------------DEDEEKGR------GSESEQSEEDGKRKTK 747

Query: 184 LKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS 223
            K+   KG+A+   E SDS        SS + E   TS S
Sbjct: 748 KKVPERKGEASSSDEGSDS--------SSSSSESEMTSES 779



>gi|54035054|gb|AAH35311.1|   Dermokine [Homo sapiens]
 gi|33504489|ref|NP_201574.2|   dermokine [Homo sapiens]
 gi|49659960|gb|AAT68269.1|   dermokine-beta [Homo sapiens]
          Length = 476

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 82/326 (25%), Positives = 122/326 (37%), Gaps = 61/326 (18%)

Query: 152 ATGEDEDKSRERWDAGNSRSEDSPAVGTGS-----SGLKLGAGKGDA-AFGFEVSDS-NS 204
           A  E   K+  +   G + S+ S A+G G+     +G++   G G A A G  V ++ ++
Sbjct: 46  ALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGAADALGNRVGEAAHA 105

Query: 205 FGDTGIS------------SKTVEGNQTSSSG--GSVSIDLGDTSFRSENQFVGGGSLN- 249
            G+TG              +  V G+     G  G+     G   F S+    G G  N 
Sbjct: 106 LGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNP 165

Query: 250 -SISNLWDSGQEG-----FGINEIG------GNG----MSGSVSAEAGFKGFGSDSSSSV 293
             +   W  G  G     FG+N  G      GNG       +        G+GS  +S+ 
Sbjct: 166 GGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQ 225

Query: 294 EKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGIS 353
            +        G   GG   N      +QSG +G+ S   + NG     + +G  +     
Sbjct: 226 NEGCTNPPPSGS--GGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSG 283

Query: 354 EDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGG 413
             SG   G+S          GG+R  S      G+ S GS   + GG      SG G G 
Sbjct: 284 GSSGGSSGNS----------GGSRGDSGSESSWGS-STGSSSGNHGG------SGGGNGH 326

Query: 414 K-SADELGVGASGLNEFGETGLSGSE 438
           K   ++ G  A G    GE+G+  SE
Sbjct: 327 KPGCEKPGNEARG---SGESGIQNSE 349



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 45/179 (25%), Positives = 75/179 (41%), Gaps = 11/179 (6%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG+G+ GS   + G  G G  +   +   W+  +  G + G    N + +   Q G+ G 
Sbjct: 146 GGHGIFGS---QGGLGGQGQGNPGGLGTPWVHGYP-GNSAGSFGMNPQGAPWGQGGNGG- 200

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAG 387
              +F  N  G + A+ G+ +    +++ G             S +GG     S    +G
Sbjct: 201 -PPNFGTNTQG-AVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSG 258

Query: 388 NLSPGSDVSDSGGNTWSSDSG--SGG--GGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           +    ++ S SGG++  S SG  SGG  GG S +  G      +E      +GS  G+H
Sbjct: 259 SNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNH 317



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 59/235 (25%), Positives = 81/235 (34%), Gaps = 34/235 (14%)

Query: 72  EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFY 131
           E +   G F S    G   +  P    GLG P       G+S  + G   +  P G    
Sbjct: 143 ETSGGHGIFGSQGGLGGQGQGNPG---GLGTPW-VHGYPGNSAGSFGMNPQGAPWGQGGN 198

Query: 132 GSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKG 191
           G   +  ++ +  +    +G+          R    N    + P  G+G      G G G
Sbjct: 199 GGPPNFGTNTQGAVAQPGYGSV---------RASNQNEGCTNPPPSGSGGGSSNSGGGSG 249

Query: 192 DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSI 251
             +     S S S GD    S +   +  SSSGGS     G +S        GG S NS 
Sbjct: 250 SQSGS---SGSGSNGDNNNGSSSGGSSSGSSSGGS----SGGSS--------GGSSGNSG 294

Query: 252 SNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGET 306
            +  DSG E            +GS S   G  G G+      EK      G GE+
Sbjct: 295 GSRGDSGSES------SWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGES 343



>gi|58036935|emb|CAH18704.2|   hypothetical protein [Homo sapiens]
          Length = 1149

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 42/160 (26%), Positives = 61/160 (38%), Gaps = 26/160 (16%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSED 123
           ++A  P   +     +   S+     ++ KPF+S   G  G  E    D +    S S+ 
Sbjct: 713 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKS 772

Query: 124 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSG 183
           +   G    SS S + D+             EDE+K R       S SE S   G   + 
Sbjct: 773 SSESGSGESSSESDNEDQ------------DEDEEKGR------GSESEQSEEDGKRKTK 814

Query: 184 LKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS 223
            K+   KG+A+   E SDS        SS + E   TS S
Sbjct: 815 KKVPERKGEASSSDEGSDS--------SSSSSESEMTSES 846



>gi|51472794|ref|XP_370934.3|   PREDICTED: similar to CG15828-PA [Homo sapiens]
          Length = 679

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 37/144 (25%), Positives = 60/144 (41%), Gaps = 16/144 (11%)

Query: 945  LKFQNGIIVIWDKNTRLSVILDPNW-NGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFG 1003
            L  ++G+ V  D  T L  +    W +G   GL G N+ +  ++      S+A    E  
Sbjct: 439  LASEDGVSVSCDVPTGLCSLTLGLWQHGISAGLLGTNDNEAGNELMLPDGSMARSLEELS 498

Query: 1004 NSWKTSQECSDTVA--QTFPCDSN-PYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVC 1060
             +W+   +C  T    Q   C    P C  WA  +      S+ RDC   VDP+ +  +C
Sbjct: 499  LAWQVGGDCRATEKPQQEQACPGQLPAC--WAFFEGP---HSSLRDCFRVVDPTPFLSLC 553

Query: 1061 IEEAC-------ACDMEGKYLGFC 1077
            ++  C       AC++   Y+  C
Sbjct: 554  VQVPCGTQELQPACNLAAAYIHLC 577



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 35/171 (20%), Positives = 70/171 (40%), Gaps = 18/171 (10%)

Query: 596 GCTCPEDKIQIFNASSSYLQVETYFHVKLQIQI-VPVMQLYVSMPPNQFTDTVGLCGSYN 654
           G +CP+ K+          ++E      + +   VP     +++   Q   + GL G+ +
Sbjct: 417 GDSCPDLKLHPATTRKDVSRIELASEDGVSVSCDVPTGLCSLTLGLWQHGISAGLLGTND 476

Query: 655 NKAEDDFMSSQNILEKTSQAFANSWEMMSCPKGNPSSCISIEKEKFAERHCGILLDS--- 711
           N+A ++ M     + ++ +  + +W++          C + EK +  E+ C   L +   
Sbjct: 477 NEAGNELMLPDGSMARSLEELSLAWQV-------GGDCRATEKPQ-QEQACPGQLPACWA 528

Query: 712 --SGP---LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACA 757
              GP   L  C  +V+P P+   C +  C  +  Q   C +   Y+  CA
Sbjct: 529 FFEGPHSSLRDCFRVVDPTPFLSLCVQVPCGTQELQPA-CNLAAAYIHLCA 578



>gi|51471096|ref|XP_296117.4|   PREDICTED: similar to Heterogeneous nuclear ribonucleoprotein A1
           (Helix-destabilizing protein) (Single-strand binding
           protein) (hnRNP core protein A1) [Homo sapiens]
          Length = 441

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 67/247 (27%), Positives = 93/247 (37%), Gaps = 48/247 (19%)

Query: 187 GAGKGDAAFGFEVSDSNSFGDTGISSKTVEGN----QTSSSGGSVSIDLGDTSFRSEN-- 240
           G+GK    F F   D + F D  +  K   GN    +   +     +    +  RS+N  
Sbjct: 76  GSGK-KKRFAFVTFDGHDFVDKTVIQKYHIGNGHNCEVRKALSKQEVASASSRQRSQNCS 134

Query: 241 -QFVGG--GSLNSISNLWD----SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSV 293
             F GG  GS   I N       SG  GFG    G    SG   +E  + GFG+D+    
Sbjct: 135 GNFGGGHGGSFGGIDNFGHGENFSGHGGFG----GSCDSSGYGGSEDDYNGFGNDT---- 186

Query: 294 EKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS---SARNGFENSS 350
                   G G   GG      +S    SG  G  +K   G+G  DS    +R GF + S
Sbjct: 187 --------GYG---GGGPGYSEESQGYGSGGEGCRNK---GSGFCDSYNDGSRRGFGSGS 232

Query: 351 GISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL-SPGSDVSDSGGNTWSSDSGS 409
           G +  SG       ++         N+    +P +AGN     SD    GG  ++     
Sbjct: 233 GSNCRSGRRYNDFGKY--------NNQSSDFEPMKAGNFEGRSSDPYGGGGQYFAKPRNQ 284

Query: 410 GGGGKSA 416
           GG G S+
Sbjct: 285 GGYGGSS 291



>gi|1019902|gb|AAC50219.1|   beta-NAP
 gi|1583571|prf||2121258A   beta-NAP protein
          Length = 1081

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 42/160 (26%), Positives = 61/160 (38%), Gaps = 26/160 (16%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSED 123
           ++A  P   +     +   S+     ++ KPF+S   G  G  E    D +    S S+ 
Sbjct: 645 EEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKS 704

Query: 124 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSG 183
           +   G    SS S + D+             EDE+K R       S SE S   G   + 
Sbjct: 705 SSESGSGESSSESDNEDQ------------DEDEEKGR------GSESEQSEEDGKRKTK 746

Query: 184 LKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS 223
            K+   KG+A+   E SDS        SS + E   TS S
Sbjct: 747 KKVPERKGEASSSDEGSDS--------SSSSSESEMTSES 778



>gi|51473184|ref|XP_064152.6|   PREDICTED: sarcalumenin [Homo sapiens]
          Length = 924

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 90/427 (21%), Positives = 143/427 (33%), Gaps = 60/427 (14%)

Query: 19  GKIAASRSGG-----------FSYGSSSSGDLDR----------KKPLFSLEFGSPGETE 57
           G++  S SGG           FS G +S  + +R          KK L     G   E+ 
Sbjct: 40  GQLQVSASGGTEDVGNLLENHFSAGDASLEEKERALYADTAPQDKKLLLHYPDGREAESP 99

Query: 58  DKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG 117
            K+     +  P  E + +      S   G+ D           A G  E+K+G    + 
Sbjct: 100 KKTPASAASAGPDPEASLSNASATESPPPGERDDRD--------AAGPGEEKNGPPVASA 151

Query: 118 GSKSEDTPPGGFF------YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRS 171
                  PPGG        +   SSG+   ++      FG   E          AG    
Sbjct: 152 ------LPPGGAKGPVEEEWPEPSSGEGQGEEET---GFGLPTEGTASGEAGGQAGGHEL 202

Query: 172 EDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDL 231
            +      G S L  GA  G A    E +  +S GD G+     E   +   G   ++  
Sbjct: 203 PEEVQEVQGDS-LVQGAVAGTAEPKAEGASPHSEGD-GVGPLNAEAEGSPGPGEEPAVPE 260

Query: 232 GDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSS 291
           G     +    VGG S   I       Q   G  + G  G +   SAE G  G  S  + 
Sbjct: 261 GAPDVAA----VGGESEPDIDT-----QASEGTEDQGEPGPAAEASAEPG--GAQSVKAG 309

Query: 292 SVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
             E++   E    +    +       GS    + G  S++      GD ++    E + G
Sbjct: 310 DTEENQSPEMTEEDADEASSEEESGDGSGSEEEGGVPSEEESEEDSGDGASS---EEAEG 366

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
            SE++     + +  E    + GG+ + + +  E G+     +  + G      +   GG
Sbjct: 367 ASEEATEPQEAGEPQEAREPQEGGDLQEAEESQEGGDPQEAEEPQEGGAPQEGGEPQEGG 426

Query: 412 GGKSADE 418
             + A E
Sbjct: 427 DPQEARE 433



>gi|190404|gb|AAA63248.1|   profilaggrin
          Length = 797

 Score = 43.9 bits (102), Expect = 0.002
 Identities = 122/523 (23%), Positives = 187/523 (35%), Gaps = 83/523 (15%)

Query: 28  GFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQ----------------RQDAGSPKS 71
           G S GS +S    R+    S +  S G +ED  R+                R  +  P+S
Sbjct: 260 GQSEGSRTSR---RQGSSVSQDSDSQGHSEDSERRSGSASRNHRGSAQEQSRDGSRHPRS 316

Query: 72  EDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGS----KSEDTPPG 127
                 G  +S+ SS  S       S G  A    E     + +  GS     ++ +   
Sbjct: 317 HHEDRAGHGDSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHYQQSADSSRHS 376

Query: 128 GFFYGSSSSG--DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLK 185
           G  +G +SS   DS  +    S      G  ED   +   A         +    + G  
Sbjct: 377 GIGHGQASSAVRDSGHRGSSGSQASDNEGHSEDSDTQSVSAHRQAGRHHESHQESTRGRS 436

Query: 186 LGAGKGDAAFGFEVS----DSNSFGDTGISSKTVEGNQ----TSSSGGSVSIDLGDTSFR 237
            G      +F ++VS      ++ G  G S+   +G++      SS  S S +  DT   
Sbjct: 437 RGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRG 496

Query: 238 SENQFVGG--GSLN--SISNLWDSGQEGFGINEIG----GNGMSGSVSAEA--------- 280
                 GG  GS +  S+     SG         G     +G SGS SA           
Sbjct: 497 HPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSG 556

Query: 281 -GFKGFGS---DSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
            G +  GS   ++S+  + S   + G GE+ G      R  GS+ S D+ + +   D   
Sbjct: 557 DGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRS--RRQGSSVSQDSDSEAYPEDSER 614

Query: 337 VGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVS 396
             +S++RN   +S   S D     GSS +      ++   +  SS   E G+ S  S   
Sbjct: 615 RSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLS--Q 672

Query: 397 DSGGNTWSSDSGSGGGGKS------ADELGVGASGL-----------NEFGETGLSGSEK 439
           DS  ++     GS     S        E   G SGL            ++GE+G   S+ 
Sbjct: 673 DSAYHSGIQSRGSPHSSSSYHYQSEGTERQKGQSGLVWRHGSYGSADYDYGESGFRHSQH 732

Query: 440 GSHIPEATP-KYSETNAI-----IGQDINEHIAN--SKIPGDC 474
           GS    + P  + E + I      G+D   + A   +K PG C
Sbjct: 733 GSVSYNSNPVLFKERSDICKASAFGKDHPRYYATYINKDPGLC 775



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 65/311 (20%), Positives = 107/311 (34%), Gaps = 21/311 (6%)

Query: 153 TGEDEDKSRERWDAGNSRSEDSPAVG---------TGSSGLKLGAGKGDAAFGFEVSDSN 203
           +G    +S  R  A +S  +   + G         +  S    G G G A+    V DS 
Sbjct: 10  SGTRHTESSSRGQAASSHEQARSSAGERHGSHHQQSADSSRHAGIGHGQASSA--VRDSG 67

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFG 263
             G  G  +   EG+   S   SVS        +  +Q    G     S    S      
Sbjct: 68  HRGYRGSQATDSEGHSEDSDTQSVSAQGQAGPHQQSHQESARGQSGESSGRSGSFLYQVS 127

Query: 264 INEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL-------GETKGGAEFNFRD 316
            +E   +    SV +  G +G   D +    +    + G        G ++GG + +  +
Sbjct: 128 THEQSESTHGQSVPSTGGRQGSHHDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHHE 187

Query: 317 SGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
              ++SG +G+        G  D+S       S+          G   +H     +   +
Sbjct: 188 QSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTHDQEQSGDGSRHSGSRHQEASS 247

Query: 377 RKRSSDPDEA-GNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLS 435
              SS   +A    S GS  S   G++ S DS S G  + ++    G++  N  G +   
Sbjct: 248 WADSSRHSQAVQGQSEGSRTSRRQGSSVSQDSDSQGHSEDSERRS-GSASRNHRG-SAQE 305

Query: 436 GSEKGSHIPEA 446
            S  GS  P +
Sbjct: 306 QSRDGSRHPRS 316



>gi|346312|pir||A45135   profilaggrin - human (fragment)
 gi|553621|gb|AAA60177.1|   profilaggrin
          Length = 591

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 75/299 (25%), Positives = 114/299 (38%), Gaps = 42/299 (14%)

Query: 59  KSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGG 118
           +SR R+  GS  S+D       +S   S DS+R     S      G A ++S D      
Sbjct: 286 ESRTRKRRGSRVSQDR------DSEGHSEDSERHSG--SASRNHHGSAWEQSRDGSRHPR 337

Query: 119 SKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSR----ERWDAGNSRSEDS 174
           S  ED    G  + + SS  S  +    S   G T    +++R    ER  +G+ +S DS
Sbjct: 338 SHDEDRASHG--HSADSSRQSGTRHAETSSR-GQTASSHEQARSSPGERHGSGHQQSADS 394

Query: 175 P---AVGTGSSGLKL---------GAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSS 222
               A G G +   +         G+   D+    E SD+ S    G +    + +Q S+
Sbjct: 395 SRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQEST 454

Query: 223 SGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF 282
            G S     G+ S RS      G SL  +S   +      G       G  GS   +A  
Sbjct: 455 RGRS-----GERSGRS------GSSLYQVST-HEQPDSAHGRTGTSTGGRQGSHHEQARD 502

Query: 283 KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
               S  S+S E         G ++GG + +  +   N+SG +G+        G  D+S
Sbjct: 503 S---SRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS 558



>gi|106019|pir||A32947   filaggrin precursor - human (fragment)
 gi|1346008|sp|P20930|FILA_HUMAN   Filaggrin precursor
 gi|182605|gb|AAA52454.1|   filaggrin
          Length = 416

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 73/347 (21%), Positives = 115/347 (33%), Gaps = 45/347 (12%)

Query: 76  AGGFFNSSSSSGDSDRTKPFF-SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSS 134
           +G   + ++S G SD +     S       + +++SGD     GS+  +        G S
Sbjct: 100 SGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHS 159

Query: 135 SSGDSDKKKPLFSFEFGAT-GEDED-----KSRERWDAGNSRSEDSPAVGTGSSGLKLGA 188
             G    + P  S  +G++  +D D     +  ERW    SR+    A      G +   
Sbjct: 160 QVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR 219

Query: 189 GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSL 248
              +   G   S  +S       ++T  G Q +SS        GD       Q       
Sbjct: 220 SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGDRHGSHHQQSADSSRH 279

Query: 249 NSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
           + I +    GQ    + + G  G SGS +++       SD+ S                 
Sbjct: 280 SGIGH----GQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV---------------- 319

Query: 309 GAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEV 368
                   S   Q+G +  S ++         SAR     +SG S      + + +Q E 
Sbjct: 320 --------SAHGQAGSHQQSHQE---------SARGRSGETSGHSGSFLYQVSTHEQSES 362

Query: 369 ELSRTG-GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGK 414
               TG   R R     E    S     S  G +T     GS  GG+
Sbjct: 363 SHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGR 409



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 73/318 (22%), Positives = 116/318 (36%), Gaps = 49/318 (15%)

Query: 180 GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG---GSVSIDLGDTS- 235
           G +G   G  +G  +   +  DS+    +     T+ G++ SSSG   GS    L D S 
Sbjct: 41  GRTGTSTGGRQG--SHHQQARDSSRHSTSQEGQDTIHGHRGSSSGGRQGSHYEQLVDRSG 98

Query: 236 ------------FRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFK 283
                        RS+      GS ++     +  Q G G    G      S  A++   
Sbjct: 99  HSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGH 158

Query: 284 ---GFGSDSSSSVEKSWLFEFGL-GETKGGAEFNFRDSGSNQSGDNGNS----------- 328
              G G        ++W   F    +++G +E + R SGS     +G++           
Sbjct: 159 SQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP 218

Query: 329 ---SKDFDGNG-VGDSSARNGFENSSGISEDSGVILGSSDQHEVEL-SRTGGNRKRSSDP 383
               +D  G+G   DSS ++G  ++   +   G    S +Q       R G + ++S+D 
Sbjct: 219 RSHQEDRAGHGHSADSSRQSGTRHTQ--TSSGGQAASSHEQARSSAGDRHGSHHQQSADS 276

Query: 384 DEAGNLSPG---SDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG 440
                +  G   S V DSG   +S    S   G S D      S        G +GS + 
Sbjct: 277 SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSED------SDTQSVSAHGQAGSHQQ 330

Query: 441 SHIPEATPKYSETNAIIG 458
           SH   A  +  ET+   G
Sbjct: 331 SHQESARGRSGETSGHSG 348



>gi|57208868|emb|CAI41110.1|   nucleoporin 214kDa [Homo sapiens]
 gi|285957|dbj|BAA03515.1|   KIAA0023 [Homo sapiens]
          Length = 2093

 Score = 43.1 bits (100), Expect = 0.003
 Identities = 67/267 (25%), Positives = 99/267 (37%), Gaps = 37/267 (13%)

Query: 208  TGISSKTVEGN-QTSSSGGSVSID-------LGDTSFRSENQFVGGGSLNSISNLWDSGQ 259
            TG ++ T     Q SSSG S            G T+F   + F  G S +S ++++   Q
Sbjct: 1669 TGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQASVF--GQSASSAASVFSFSQ 1726

Query: 260  EGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGS 319
             GF      G   S + ++ +G   FG+ SS+S   S+ F      T GG          
Sbjct: 1727 PGFSSVPAFGQPASSTPTSTSG-SVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAF 1785

Query: 320  NQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEV--ELSRTGGNR 377
             QS   G     F G     ++A      +SG S       GSS+   V  + + TGG  
Sbjct: 1786 GQSPGFGQGGSVFGGTSAATTTAA-----TSGFSFCQASGFGSSNTGSVFGQAASTGGIV 1840

Query: 378  KRSSDPDEAGNLSPGSDVSDSGG----------------NTWSSDSGSGGGGKSADELGV 421
                    +G++    +    GG                N +SS SG  G   +++   +
Sbjct: 1841 FGQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNL 1900

Query: 422  -GASGLNEFGETGLSGSEKGSHIPEAT 447
             G SG   FG  G + S  G   P  T
Sbjct: 1901 FGNSGAKTFG--GFASSSFGEQKPTGT 1925



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 71/318 (22%), Positives = 100/318 (31%), Gaps = 70/318 (22%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            G  A    G  ++G +S              F  PG +   +  +  + +P S    +G 
Sbjct: 1693 GTTAPGVFGQTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTST---SGS 1749

Query: 79   FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGD 138
             F ++SS+  S      FS G  +P       G S      +S     GG  +G +S+  
Sbjct: 1750 VFGAASSTSSSSS----FSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAAT 1805

Query: 139  SDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFE 198
            +      FSF                           A G GSS                
Sbjct: 1806 TTAATSGFSF-------------------------CQASGFGSS---------------- 1824

Query: 199  VSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSI------- 251
             +  + FG    +   V G Q+SSS GSV        F S N   GGG  + +       
Sbjct: 1825 -NTGSVFGQAASTGGIVFGQQSSSSSGSV--------FGSGNTGRGGGFFSGLGGKPSQD 1875

Query: 252  ---SNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                N + S   GFG             S    F GF S S    + +  F  G G    
Sbjct: 1876 AANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSV-- 1933

Query: 309  GAEFNFRDSGSNQSGDNG 326
             A   F  S  N++G  G
Sbjct: 1934 -ASQGFGFSSPNKTGGFG 1950



>gi|7710983|emb|CAB90290.1|   insulin receptor substrate 4 [Homo sapiens]
 gi|4504733|ref|NP_003595.1|   insulin receptor substrate 4 [Homo sapiens]
 gi|2388658|gb|AAC51738.1|   insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 42.7 bits (99), Expect = 0.004
 Identities = 47/150 (31%), Positives = 58/150 (38%), Gaps = 21/150 (14%)

Query: 305 ETKGGAEFNFRDSGS-----NQSGDNG-----NSSKDFDGNGVGDSSARNG---FENSSG 351
           E  G    NF + G+     +Q G  G     N+    +G G G     NG     +SSG
Sbjct: 459 EVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSG 518

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
            ++ SG   GS          +GGN+        AG    G      GG+      GSGG
Sbjct: 519 GNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH------GSGG 572

Query: 412 GGKSADELGVGASGLNEFGETGLSGSEKGS 441
           G    D  G G  G N  G  G SGS KGS
Sbjct: 573 GQGPGDGHGSG-GGKNSGGGKG-SGSGKGS 600



>gi|4210363|emb|CAA50559.1|   FUS gycline rich protein [Homo sapiens]
 gi|3582783|gb|AAC35284.1|   FUS/TLS protein [Homo sapiens]
          Length = 525

 Score = 42.7 bits (99), Expect = 0.004
 Identities = 65/290 (22%), Positives = 106/290 (36%), Gaps = 38/290 (13%)

Query: 196 GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT--SFRSENQFVGGGSLNSISN 253
           G+    S  +G    S  + +   TS  G S     G +  S+ +++   G GS     +
Sbjct: 24  GYSQQSSQPYGQQSYSGYS-QSTDTSGYGQSSYSSYGQSQNSYGTQSTPQGYGSTGGYGS 82

Query: 254 LWDSGQEGFGI-NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEF 312
              S Q  +G  +   G G   + S+ +G  G  S SSS            G+ + G+ +
Sbjct: 83  S-QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS-----------YGQPQSGS-Y 129

Query: 313 NFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSR 372
           + + S   Q    G         G G    +N + +SSG     G   G+  Q +  +S 
Sbjct: 130 SQQPSYGGQQQSYGQQQSYNPPQGYGQ---QNQYNSSSGGGGGGGGG-GNYGQDQSSMSS 185

Query: 373 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGG------KSADELGVGASGL 426
            GG+     + D++G    G       G      SG GGGG      +S+        G 
Sbjct: 186 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGG 245

Query: 427 NEFGETGLSGSEKGSHIPEATPK-----------YSETNAIIGQDINEHI 465
              G  G+ GS++G       P+            S+ N I  Q + E++
Sbjct: 246 GRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENV 295



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 90/388 (23%), Positives = 130/388 (33%), Gaps = 68/388 (17%)

Query: 64  QDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSE 122
           Q   S  ++ TP G  + S+   G S  ++  +      PG  +  +  S     GS S+
Sbjct: 60  QSQNSYGTQSTPQG--YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQ 117

Query: 123 DTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSS 182
            +      YG   SG S  ++P +  +  + G+ +  +  +     ++   S   G    
Sbjct: 118 SSS-----YGQPQSG-SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG---- 167

Query: 183 GLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQT-SSSGGSVSIDLGDTSFRSENQ 241
               G G G   +G + S  +S G +G       GNQ  S  GGS      D   R    
Sbjct: 168 ----GGGGGGGNYGQDQSSMSSGGGSGGGY----GNQDQSGGGGSGGYGQQDRGGRGRGG 219

Query: 242 FVGGGSLNSISNLWDSG---QEGFGINEIGGNGMSGSVSAEAGFKGFG---------SDS 289
             GGG          SG     G G    G  GM G  S   GF  FG            
Sbjct: 220 SGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSE 277

Query: 290 SSSVEKSWLFEFGLGE--TKGGAEFNFRDSG----SNQSGD--------------NGNSS 329
             + + + +F  GLGE  T       F+  G    + ++G                G ++
Sbjct: 278 QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 337

Query: 330 KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN----RKRSSDPDE 385
             FD       SA+   +   G       I  S      + +R GGN    R R      
Sbjct: 338 VSFD----DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGR 393

Query: 386 AGNLSPGSDVSDSGGNTWSSDSGSGGGG 413
            G    GS     GG      SG GGGG
Sbjct: 394 GGYGGGGS----GGGGRGGFPSGGGGGG 417



>gi|30583101|gb|AAP35795.1|   fusion, derived from t(12;16) malignant liposarcoma [Homo sapiens]
 gi|12803287|gb|AAH02459.1|   Fusion (involved in t(12;16) in malignant liposarcoma), isoform a
           [Homo sapiens]
 gi|4826734|ref|NP_004951.1|   fusion (involved in t(12;16) in malignant liposarcoma) isoform a
           [Homo sapiens]
 gi|12653267|gb|AAH00402.1|   Fusion (involved in t(12;16) in malignant liposarcoma) [Homo
           sapiens]
 gi|423076|pir||S33799   RNA-binding protein FUS, nuclear - human
 gi|3582784|gb|AAC35285.1|   FUS/TLS protein [Homo sapiens]
 gi|386157|gb|AAB27102.1|   TLS [Homo sapiens]
 gi|48145611|emb|CAG33028.1|   FUS [Homo sapiens]
 gi|544357|sp|P35637|FUS_HUMAN   RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated
           in liposarcoma protein) (POMp75) (75 kDa DNA-pairing
           protein)
          Length = 526

 Score = 42.7 bits (99), Expect = 0.004
 Identities = 65/291 (22%), Positives = 106/291 (36%), Gaps = 39/291 (13%)

Query: 196 GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG---DTSFRSENQFVGGGSLNSIS 252
           G+    S  +G    S  + +   TS  G S     G   +T + +++   G GS     
Sbjct: 24  GYSQQSSQPYGQQSYSGYS-QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYG 82

Query: 253 NLWDSGQEGFGI-NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAE 311
           +   S Q  +G  +   G G   + S+ +G  G  S SSS            G+ + G+ 
Sbjct: 83  SS-QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS-----------YGQPQSGS- 129

Query: 312 FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELS 371
           ++ + S   Q    G         G G    +N + +SSG     G   G+  Q +  +S
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQ---QNQYNSSSGGGGGGGGG-GNYGQDQSSMS 185

Query: 372 RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGG------KSADELGVGASG 425
             GG+     + D++G    G       G      SG GGGG      +S+        G
Sbjct: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245

Query: 426 LNEFGETGLSGSEKGSHIPEATPK-----------YSETNAIIGQDINEHI 465
               G  G+ GS++G       P+            S+ N I  Q + E++
Sbjct: 246 GGRGGRGGMGGSDRGGFNKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENV 296



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 88/381 (23%), Positives = 128/381 (33%), Gaps = 68/381 (17%)

Query: 71  SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGF 129
           ++ TP G  + S+   G S  ++  +      PG  +  +  S     GS S+ +     
Sbjct: 68  TQSTPQG--YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS---- 121

Query: 130 FYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
            YG   SG S  ++P +  +  + G+ +  +  +     ++   S   G        G G
Sbjct: 122 -YGQPQSG-SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG--------GGG 171

Query: 190 KGDAAFGFEVSDSNSFGDTGISSKTVEGNQT-SSSGGSVSIDLGDTSFRSENQFVGGGSL 248
            G   +G + S  +S G +G       GNQ  S  GGS      D   R      GGG  
Sbjct: 172 GGGGNYGQDQSSMSSGGGSGGGY----GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227

Query: 249 NSISNLWDSG---QEGFGINEIGGNGMSGSVSAEAGFKGFG---------SDSSSSVEKS 296
                   SG     G G    G  GM G  S   GF  FG              + + +
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNN 285

Query: 297 WLFEFGLGE--TKGGAEFNFRDSG----SNQSGD--------------NGNSSKDFDGNG 336
            +F  GLGE  T       F+  G    + ++G                G ++  FD   
Sbjct: 286 TIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD--- 342

Query: 337 VGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN----RKRSSDPDEAGNLSPG 392
               SA+   +   G       I  S      + +R GGN    R R       G    G
Sbjct: 343 -DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGG 401

Query: 393 SDVSDSGGNTWSSDSGSGGGG 413
           S     GG      SG GGGG
Sbjct: 402 S----GGGGRGGFPSGGGGGG 418



>gi|547749|sp|P13645|K1CJ_HUMAN   Keratin, type I cytoskeletal 10 (Cytokeratin 10) (K10) (CK 10)
          Length = 593

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 47/170 (27%), Positives = 57/170 (33%), Gaps = 44/170 (25%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           + G  S+  G +G GS             +G G + GG+      SG    G +G SS  
Sbjct: 453 LEGEGSSGGGGRGGGSFGGG---------YGGGSSGGGS------SGGGYGGGHGGSS-- 495

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
             G G G  S+  G   SSG                      GG    SS     G  S 
Sbjct: 496 --GGGYGGGSSGGG---SSG----------------------GGYGGGSSSGGHGGGSSS 528

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           G     S G      SG GGGG      G G+S    +G    SG  K S
Sbjct: 529 GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSS 578



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 14/138 (10%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
           GGGS         SG    G    GG+G S       G  G GS             +G 
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGGGSSGGG---------YGG 515

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSS 363
           G + GG        GS+  G  G+SS  + G   G      G  +S G S   G   G S
Sbjct: 516 GSSSGG-----HGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGS 570

Query: 364 DQHEVELSRTGGNRKRSS 381
                + S +G   + SS
Sbjct: 571 SSGGHKSSSSGSVGESSS 588



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 44/177 (24%)

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G+    GG +   +  GG+  GSS  G S           G  G     S   +  G+S 
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGG---------GYGGGHGGSSGGGYGGGSS- 504

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
                  G GSSG   G G      G     S+S G  G SS    G  +   GG     
Sbjct: 505 -------GGGSSGGGYGGGSSSGGHG---GGSSSGGHGGSSSGGYGGGSSGGGGGGYG-- 552

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
            G +S        GGGS         S   G+G    GG+   G  S+ +G  G  S
Sbjct: 553 -GGSS--------GGGS---------SSGGGYG----GGSSSGGHKSSSSGSVGESS 587



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 36/131 (27%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMS------------GSVSAEAGFKGFGSDSSS 291
           GGG ++S+      G  G G +  G +G S            GS     G  GFG  S  
Sbjct: 27  GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFH 86

Query: 292 SVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
               S  F    G + GG  F          G  G  S  F G G G      GF    G
Sbjct: 87  GSYGSSSFGGSYGGSFGGGNFG--------GGSFGGGS--FGGGGFGGGGFGGGF--GGG 134

Query: 352 ISEDSGVILGS 362
              D G++ G+
Sbjct: 135 FGGDGGLLSGN 145



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 7/76 (9%)

Query: 367 EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGL 426
           E E S  GG R         G+   G     SGG +     G G GG S    G G+SG 
Sbjct: 454 EGEGSSGGGGRG-------GGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGG 506

Query: 427 NEFGETGLSGSEKGSH 442
              G     GS  G H
Sbjct: 507 GSSGGGYGGGSSSGGH 522



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 37/143 (25%), Positives = 46/143 (32%), Gaps = 18/143 (12%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           G+   S  GG+  GSS  G             G  G     S      G      +  GG
Sbjct: 463 GRGGGSFGGGYGGGSSGGGSSG----------GGYGGGHGGSSGGGYGGGSSGGGSSGGG 512

Query: 79  FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA--GGSKSEDTPPGGFFYGSSSS 136
           +   SSS G    +      G  + G     SG       GGS    +  GG + G SSS
Sbjct: 513 YGGGSSSGGHGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 572

Query: 137 GDSDKKKPLFSFEFGATGEDEDK 159
           G         S   G+ GE   K
Sbjct: 573 GGHK------SSSSGSVGESSSK 589



>gi|71528|pir||KRHU0   keratin 10, type I, cytoskeletal - human
 gi|28317|emb|CAA32649.1|   unnamed protein product [Homo sapiens]
          Length = 593

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 47/170 (27%), Positives = 57/170 (33%), Gaps = 44/170 (25%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           + G  S+  G +G GS             +G G + GG+      SG    G +G SS  
Sbjct: 453 LEGEGSSGGGGRGGGSFGGG---------YGGGSSGGGS------SGGGYGGGHGGSS-- 495

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
             G G G  S+  G   SSG                      GG    SS     G  S 
Sbjct: 496 --GGGYGGGSSGGG---SSG----------------------GGYGGGSSSGGHGGGSSS 528

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           G     S G      SG GGGG      G G+S    +G    SG  K S
Sbjct: 529 GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSS 578



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 14/138 (10%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
           GGGS         SG    G    GG+G S       G  G GS             +G 
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGGGSSGGG---------YGG 515

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSS 363
           G + GG        GS+  G  G+SS  + G   G      G  +S G S   G   G S
Sbjct: 516 GSSSGG-----HGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGS 570

Query: 364 DQHEVELSRTGGNRKRSS 381
                + S +G   + SS
Sbjct: 571 SSGGHKSSSSGSVGESSS 588



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 44/177 (24%)

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G+    GG +   +  GG+  GSS  G S           G  G     S   +  G+S 
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGG---------GYGGGHGGSSGGGYGGGSS- 504

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
                  G GSSG   G G      G     S+S G  G SS    G  +   GG     
Sbjct: 505 -------GGGSSGGGYGGGSSSGGHG---GGSSSGGHGGSSSGGYGGGSSGGGGGGYG-- 552

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
            G +S        GGGS         S   G+G    GG+   G  S+ +G  G  S
Sbjct: 553 -GGSS--------GGGS---------SSGGGYG----GGSSSGGHKSSSSGSVGESS 587



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 36/131 (27%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMS------------GSVSAEAGFKGFGSDSSS 291
           GGG ++S+      G  G G +  G +G S            GS     G  GFG  S  
Sbjct: 27  GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFH 86

Query: 292 SVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
               S  F    G + GG  F          G  G  S  F G G G      GF    G
Sbjct: 87  GSYGSSSFGGSYGGSFGGGNFG--------GGSFGGGS--FGGGGFGGGGFGGGF--GGG 134

Query: 352 ISEDSGVILGS 362
              D G++ G+
Sbjct: 135 FGGDGGLLSGN 145



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 7/76 (9%)

Query: 367 EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGL 426
           E E S  GG R         G+   G     SGG +     G G GG S    G G+SG 
Sbjct: 454 EGEGSSGGGGRG-------GGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGG 506

Query: 427 NEFGETGLSGSEKGSH 442
              G     GS  G H
Sbjct: 507 GSSGGGYGGGSSSGGH 522



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 37/143 (25%), Positives = 46/143 (32%), Gaps = 18/143 (12%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           G+   S  GG+  GSS  G             G  G     S      G      +  GG
Sbjct: 463 GRGGGSFGGGYGGGSSGGGSSG----------GGYGGGHGGSSGGGYGGGSSGGGSSGGG 512

Query: 79  FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA--GGSKSEDTPPGGFFYGSSSS 136
           +   SSS G    +      G  + G     SG       GGS    +  GG + G SSS
Sbjct: 513 YGGGSSSGGHGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 572

Query: 137 GDSDKKKPLFSFEFGATGEDEDK 159
           G         S   G+ GE   K
Sbjct: 573 GGHK------SSSSGSVGESSSK 589



>gi|244509|gb|AAB21315.1|   keratin 10 V2 subdomain 142 amino acid variant [human, Peptide
           Partial, 142 aa]
          Length = 142

 Score = 42.4 bits (98), Expect = 0.006
 Identities = 47/170 (27%), Positives = 57/170 (33%), Gaps = 44/170 (25%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           + G  S+  G +G GS             +G G + GG+      SG    G +G SS  
Sbjct: 2   LEGEGSSGGGGRGGGSFGGG---------YGGGSSGGGS------SGGGYGGGHGGSS-- 44

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
             G G G  S+  G   SSG                      GG    SS     G  S 
Sbjct: 45  --GGGYGGGSSGGG---SSG----------------------GGYGGGSSSGGHGGGSSS 77

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           G     S G      SG GGGG      G G+S    +G    SG  K S
Sbjct: 78  GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSS 127



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 38/138 (27%), Positives = 48/138 (34%), Gaps = 14/138 (10%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
           GGGS         SG    G    GG+G S       G  G GS             +G 
Sbjct: 14  GGGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGGGSSGGG---------YGG 64

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSS 363
           G + GG        GS+  G  G+SS  + G   G      G  +S G S   G   G S
Sbjct: 65  GSSSGG-----HGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGS 119

Query: 364 DQHEVELSRTGGNRKRSS 381
                + S +G   + SS
Sbjct: 120 SSGGHKSSSSGSVGESSS 137



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 44/177 (24%)

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G+    GG +   +  GG+  GSS  G S           G  G     S   +  G+S 
Sbjct: 4   GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGG---------GYGGGHGGSSGGGYGGGSS- 53

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
                  G GSSG   G G      G     S+S G  G SS    G  +   GG     
Sbjct: 54  -------GGGSSGGGYGGGSSSGGHG---GGSSSGGHGGSSSGGYGGGSSGGGGGGYG-- 101

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
            G +S        GGGS         S   G+G    GG+   G  S+ +G  G  S
Sbjct: 102 -GGSS--------GGGS---------SSGGGYG----GGSSSGGHKSSSSGSVGESS 136



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 7/76 (9%)

Query: 367 EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGL 426
           E E S  GG R         G+   G     SGG +     G G GG S    G G+SG 
Sbjct: 3   EGEGSSGGGGRG-------GGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGG 55

Query: 427 NEFGETGLSGSEKGSH 442
              G     GS  G H
Sbjct: 56  GSSGGGYGGGSSSGGH 71



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 37/143 (25%), Positives = 46/143 (32%), Gaps = 18/143 (12%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           G+   S  GG+  GSS  G             G  G     S      G      +  GG
Sbjct: 12  GRGGGSFGGGYGGGSSGGGSSG----------GGYGGGHGGSSGGGYGGGSSGGGSSGGG 61

Query: 79  FFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA--GGSKSEDTPPGGFFYGSSSS 136
           +   SSS G    +      G  + G     SG       GGS    +  GG + G SSS
Sbjct: 62  YGGGSSSGGHGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 121

Query: 137 GDSDKKKPLFSFEFGATGEDEDK 159
           G         S   G+ GE   K
Sbjct: 122 GGHK------SSSSGSVGESSSK 138



>gi|19913512|gb|AAH26062.1|   Fusion (involved in t(12;16) in malignant liposarcoma) [Homo
           sapiens]
          Length = 526

 Score = 42.0 bits (97), Expect = 0.007
 Identities = 64/272 (23%), Positives = 100/272 (36%), Gaps = 35/272 (12%)

Query: 219 QTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSA 278
           Q S SG S S D   TS   ++ +   G   +      S  +G+G    GG G S S  +
Sbjct: 35  QQSYSGYSQSTD---TSGYGQSSYSSYGQSQNTGYGTQSTPQGYG--STGGYGSSQSSQS 89

Query: 279 EAG----FKGFGSD----SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
             G    + G+G      S+S    S       G+ + G+ ++ + S   Q    G    
Sbjct: 90  SYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGS-YSQQPSYGGQQQSYGQQQS 148

Query: 331 DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
                G G    +N + +SSG     G   G+  Q +  +S  GG+     + D++G   
Sbjct: 149 YNPPQGYGQ---QNQYNSSSGGGGGGGGG-GNYGQDQSSMSSGGGSGGGYGNQDQSGGGG 204

Query: 391 PGSDVSDSGGNTWSSDSGSGGGG------KSADELGVGASGLNEFGETGLSGSEKGSHIP 444
            G       G      SG GGGG      +S+        G    G  G+ GS++G    
Sbjct: 205 SGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK 264

Query: 445 EATPK-----------YSETNAIIGQDINEHI 465
              P+            S+ N I  Q + E++
Sbjct: 265 FGGPRDQGSRHDSEQDNSDNNTIFVQGLGENV 296



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 88/381 (23%), Positives = 128/381 (33%), Gaps = 68/381 (17%)

Query: 71  SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGF 129
           ++ TP G  + S+   G S  ++  +      PG  +  +  S     GS S+ +     
Sbjct: 68  TQSTPQG--YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS---- 121

Query: 130 FYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
            YG   SG S  ++P +  +  + G+ +  +  +     ++   S   G        G G
Sbjct: 122 -YGQPQSG-SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG--------GGG 171

Query: 190 KGDAAFGFEVSDSNSFGDTGISSKTVEGNQT-SSSGGSVSIDLGDTSFRSENQFVGGGSL 248
            G   +G + S  +S G +G       GNQ  S  GGS      D   R      GGG  
Sbjct: 172 GGGGNYGQDQSSMSSGGGSGGGY----GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227

Query: 249 NSISNLWDSG---QEGFGINEIGGNGMSGSVSAEAGFKGFG---------SDSSSSVEKS 296
                   SG     G G    G  GM G  S   GF  FG              + + +
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFGGPRDQGSRHDSEQDNSDNN 285

Query: 297 WLFEFGLGE--TKGGAEFNFRDSG----SNQSGD--------------NGNSSKDFDGNG 336
            +F  GLGE  T       F+  G    + ++G                G ++  FD   
Sbjct: 286 TIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFD--- 342

Query: 337 VGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN----RKRSSDPDEAGNLSPG 392
               SA+   +   G       I  S      + +R GGN    R R       G    G
Sbjct: 343 -DPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGG 401

Query: 393 SDVSDSGGNTWSSDSGSGGGG 413
           S     GG      SG GGGG
Sbjct: 402 S----GGGGRGGFPSGGGGGG 418



>gi|29736952|ref|XP_290401.1|   PREDICTED: hypothetical protein LOC340318 [Homo sapiens]
 gi|42658477|ref|XP_379877.1|   PREDICTED: similar to Nuclear envelope pore membrane protein POM
           121 (Pore membrane protein of 121 kDa) (P145) [Homo
           sapiens]
          Length = 987

 Score = 41.6 bits (96), Expect = 0.009
 Identities = 53/173 (30%), Positives = 68/173 (39%), Gaps = 35/173 (20%)

Query: 189 GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSL 248
           G   A F F  + S+ FG T          QT+SSG S S+  G T+    + F  GGS 
Sbjct: 795 GGSTAVFSFGAATSSGFGAT---------TQTASSGSSSSV-FGSTT---PSPFTFGGSA 841

Query: 249 NSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                   +G   FGIN        GS SA  G   FG+  S S   S  F  GLG+   
Sbjct: 842 AP------AGSGSFGINV----ATPGS-SATTGAFSFGAGQSGSTATSTPFTGGLGQNAL 890

Query: 309 GA-------EFNFRDSGSNQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
           G         FN   +  ++    G ++  F  N    GVG S +   F  SS
Sbjct: 891 GTTGQSTPFAFNVGSTTESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASS 943



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 48/173 (27%), Positives = 72/173 (41%), Gaps = 28/173 (16%)

Query: 29  FSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGD 88
           FS+G+++S             FG+  +T          GS     TP+   F  S++   
Sbjct: 801 FSFGAATSSG-----------FGATTQTASSGSSSSVFGST----TPSPFTFGGSAAPAG 845

Query: 89  SDRTKPFFSLGLGAPGKAEDKSGDSQDAG--GSKSEDTP-PGGFFYGSSSSGDSDKKKPL 145
           S      F + +  PG +      S  AG  GS +  TP  GG   G ++ G + +  P 
Sbjct: 846 SGS----FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGL--GQNALGTTGQSTP- 898

Query: 146 FSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA-AFGF 197
           F+F  G+T   E K      A  +  +++PA G G+SG  L  G   A A GF
Sbjct: 899 FAFNVGST--TESKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGF 949



>gi|4210364|emb|CAA50558.1|   FUS-CHOP protein fusion [Homo sapiens]
 gi|386159|gb|AAB27103.1|   TLS-CHOP [Homo sapiens]
 gi|448294|prf||1916411A   TLS-CHOP protein
          Length = 462

 Score = 41.6 bits (96), Expect = 0.009
 Identities = 59/255 (23%), Positives = 95/255 (37%), Gaps = 28/255 (10%)

Query: 196 GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG---DTSFRSENQFVGGGSLNSIS 252
           G+    S  +G    S  + +   TS  G S     G   +T + +++   G GS     
Sbjct: 24  GYSQQSSQPYGQQSYSGYS-QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYG 82

Query: 253 NLWDSGQEGFGI-NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAE 311
           +   S Q  +G  +   G G   + S+ +G  G  S SSS            G+ + G+ 
Sbjct: 83  SS-QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS-----------YGQPQSGS- 129

Query: 312 FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELS 371
           ++ + S   Q    G         G G    +N + +SSG     G   G+  Q +  +S
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQ---QNQYNSSSGGGGGGGGG-GNYGQDQSSMS 185

Query: 372 RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGG------KSADELGVGASG 425
             GG+     + D++G    G       G      SG GGGG      +S+        G
Sbjct: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRG 245

Query: 426 LNEFGETGLSGSEKG 440
               G  G+ GS++G
Sbjct: 246 GGRGGRGGMGGSDRG 260



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 54/221 (24%), Positives = 80/221 (36%), Gaps = 27/221 (12%)

Query: 71  SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAG-GSKSEDTPPGGF 129
           ++ TP G  + S+   G S  ++  +      PG  +  +  S     GS S+ +     
Sbjct: 68  TQSTPQG--YGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS---- 121

Query: 130 FYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
            YG   SG S  ++P +  +  + G+ +  +  +     ++   S   G        G G
Sbjct: 122 -YGQPQSG-SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGG--------GGG 171

Query: 190 KGDAAFGFEVSDSNSFGDTGISSKTVEGNQT-SSSGGSVSIDLGDTSFRSENQFVGGGSL 248
            G   +G + S  +S G +G       GNQ  S  GGS      D   R      GGG  
Sbjct: 172 GGGGNYGQDQSSMSSGGGSGGGY----GNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227

Query: 249 NSISNLWDSG---QEGFGINEIGGNGMSGSVSAEAGFKGFG 286
                   SG     G G    G  GM G  S   GF  FG
Sbjct: 228 GGGGYNRSSGGYEPRGRGGGRGGRGGMGG--SDRGGFNKFG 266



>gi|55956899|ref|NP_000217.2|   keratin 9 [Homo sapiens]
          Length = 623

 Score = 41.2 bits (95), Expect = 0.012
 Identities = 47/169 (27%), Positives = 60/169 (35%), Gaps = 12/169 (7%)

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +   S G+  I LG            GGS    S     G  G G +  G  G SGS 
Sbjct: 461 GQEDFESSGAGKIGLGGRGG-------SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR 513

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
               G  G GS S       +    G G + G    +   SG N  G +G+      G G
Sbjct: 514 GGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573

Query: 337 VGDSSARNGFENS----SGISEDSGVILGSSDQHEVELSRTGGNRKRSS 381
            G S +R G   S    SG   +SG   G  ++        GG   +SS
Sbjct: 574 -GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 18/161 (11%)

Query: 170 RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
           R     + G GS G   G+  G  + G     S S G +G S     G+   S GG    
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 537

Query: 230 DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNG-MSGSVSAEAGFKGFGSD 288
             G  S  S     GG   N        G  G G    GG+G   GS  +  G  GFG +
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG--GGSGSRGGSGGSHGGGSGFGGE 595

Query: 289 SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           S  S        +G GE   G       SG    G +G SS
Sbjct: 596 SGGS--------YGGGEEASG-------SGGGYGGGSGKSS 621



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 9/124 (7%)

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSV 293
           +S+ S +   GGG L S  ++  S       +  GG G  G  S+ +G+ G GS      
Sbjct: 8   SSYLSRSGGGGGGGLGSGGSIRSSYSR---FSSSGGGGGGGRFSSSSGYGG-GSSRVCGR 63

Query: 294 EKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGIS 353
                F +  G   GG       S S+  G  G  S+ F G   G  S+  GF    G  
Sbjct: 64  GGGGSFGYSYGGGSGGGF-----SASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG 118

Query: 354 EDSG 357
              G
Sbjct: 119 SGGG 122



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 40/173 (23%), Positives = 54/173 (31%), Gaps = 10/173 (5%)

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
           G    G   +S   F  +G G    R  F +SSG    S  + G         S  GG+ 
Sbjct: 21  GLGSGGSIRSSYSRFSSSGGGGGGGR--FSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSG 78

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSG-------SGGGGKSADELGVGASGLNEFG 430
              S     G    GS           S SG        G GG      G G  G   FG
Sbjct: 79  GGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFG 138

Query: 431 ETGLSGSEKGSHIPEATPKYSETNAIIGQDINEHIANSKIPGDCPNAVGKSYE 483
             G  G + G           E N+ +   +++  A  +   D  N +   Y+
Sbjct: 139 -GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYD 190



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 45/157 (28%), Positives = 52/157 (33%), Gaps = 21/157 (13%)

Query: 181 SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS---GGSVSIDLGDTSFR 237
           SS L    G G    G   S  +S+     S     G + SSS   GG  S   G     
Sbjct: 8   SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGG 67

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS             GF  + +GG G  G      G +GFG  S      S 
Sbjct: 68  SFGYSYGGGS-----------GGGFSASSLGG-GFGG------GSRGFGGASGGGYSSSG 109

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
            F  G G   GG       SG    G  G  +   DG
Sbjct: 110 GFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146



>gi|435476|emb|CAA82315.1|   cytokeratin 9 [Homo sapiens]
          Length = 623

 Score = 41.2 bits (95), Expect = 0.012
 Identities = 47/169 (27%), Positives = 60/169 (35%), Gaps = 12/169 (7%)

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +   S G+  I LG            GGS    S     G  G G +  G  G SGS 
Sbjct: 461 GQEDFESSGAGKIGLGGRGG-------SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR 513

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
               G  G GS S       +    G G + G    +   SG N  G +G+      G G
Sbjct: 514 GGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573

Query: 337 VGDSSARNGFENS----SGISEDSGVILGSSDQHEVELSRTGGNRKRSS 381
            G S +R G   S    SG   +SG   G  ++        GG   +SS
Sbjct: 574 -GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 18/161 (11%)

Query: 170 RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
           R     + G GS G   G+  G  + G     S S G +G S     G+   S GG    
Sbjct: 478 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 537

Query: 230 DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNG-MSGSVSAEAGFKGFGSD 288
             G  S  S     GG   N        G  G G    GG+G   GS  +  G  GFG +
Sbjct: 538 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG--GGSGSRGGSGGSHGGGSGFGGE 595

Query: 289 SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           S  S        +G GE   G       SG    G +G SS
Sbjct: 596 SGGS--------YGGGEEASG-------SGGGYGGGSGKSS 621



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 45/157 (28%), Positives = 52/157 (33%), Gaps = 21/157 (13%)

Query: 181 SSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS---GGSVSIDLGDTSFR 237
           SS L    G G    G   S  +S+     S     G + SSS   GG  S   G     
Sbjct: 8   SSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGRGGGGRFSSSSGYGGGSSRVCGRGGGG 67

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS             GF  + +GG G  G      G +GFG  S      S 
Sbjct: 68  SFGYSYGGGS-----------GGGFSASSLGG-GFGG------GSRGFGGASGGGYSSSG 109

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
            F  G G   GG       SG    G  G  +   DG
Sbjct: 110 GFGGGFGGGSGGGFGGGYGSGFGGLGGFGGGAGGGDG 146



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 44/188 (23%), Positives = 59/188 (31%), Gaps = 15/188 (7%)

Query: 303 LGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGS 362
           L  + GG        GS +S  +  SS    G G         F +SSG    S  + G 
Sbjct: 11  LSRSGGGGGGGLGSGGSIRSSYSRFSSSGGRGGG-------GRFSSSSGYGGGSSRVCGR 63

Query: 363 SDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSG-------SGGGGKS 415
                   S  GG+    S     G    GS           S SG        G GG  
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGF 123

Query: 416 ADELGVGASGLNEFGETGLSGSEKGSHIPEATPKYSETNAIIGQDINEHIANSKIPGDCP 475
               G G  GL  FG  G  G + G           E N+ +   +++  A  +   D  
Sbjct: 124 GGGYGSGFGGLGGFG-GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLE 182

Query: 476 NAVGKSYE 483
           N +   Y+
Sbjct: 183 NKIQDWYD 190



>gi|545257|gb|AAC60619.1|   cytokeratin 9; CK 9 [Homo sapiens]
 gi|2119236|pir||I37984   keratin 9, type I, cytoskeletal - human
 gi|453155|emb|CAA52924.1|   keratin 9 [Homo sapiens]
 gi|547748|sp|P35527|K1C9_HUMAN   Keratin, type I cytoskeletal 9 (Cytokeratin 9) (K9) (CK 9)
          Length = 622

 Score = 41.2 bits (95), Expect = 0.012
 Identities = 47/169 (27%), Positives = 60/169 (35%), Gaps = 12/169 (7%)

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +   S G+  I LG            GGS    S     G  G G +  G  G SGS 
Sbjct: 460 GQEDFESSGAGKIGLGGRGG-------SGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSR 512

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNG 336
               G  G GS S       +    G G + G    +   SG N  G +G+      G G
Sbjct: 513 GGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 572

Query: 337 VGDSSARNGFENS----SGISEDSGVILGSSDQHEVELSRTGGNRKRSS 381
            G S +R G   S    SG   +SG   G  ++        GG   +SS
Sbjct: 573 -GGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 620



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 18/161 (11%)

Query: 170 RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
           R     + G GS G   G+  G  + G     S S G +G S     G+   S GG    
Sbjct: 477 RGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGG 536

Query: 230 DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNG-MSGSVSAEAGFKGFGSD 288
             G  S  S     GG   N        G  G G    GG+G   GS  +  G  GFG +
Sbjct: 537 SGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG--GGSGSRGGSGGSHGGGSGFGGE 594

Query: 289 SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           S  S        +G GE   G       SG    G +G SS
Sbjct: 595 SGGS--------YGGGEEASG-------SGGGYGGGSGKSS 620



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 9/114 (7%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGL 303
           GGG L S  ++  S       +  GG G  G  S+ +G+ G GS           F +  
Sbjct: 17  GGGGLGSGGSIRSSYSR---FSSSGGRGGGGRFSSSSGYGG-GSSRVCGRGGGGSFGYSY 72

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSG 357
           G   GG       S S+  G  G  S+ F G   G  S+  GF    G     G
Sbjct: 73  GGGSGGGF-----SASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGG 121



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 41/149 (27%), Positives = 49/149 (32%), Gaps = 19/149 (12%)

Query: 187 GAGKGDAAFGFEVSDSNS-FGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGG 245
           G G G    G  +  S S F  +G        + +S  GG  S   G     S     GG
Sbjct: 15  GGGGGGLGSGGSIRSSYSRFSSSGGRGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGG 74

Query: 246 GSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGE 305
           GS             GF  + +GG G  G      G +GFG  S      S  F  G G 
Sbjct: 75  GS-----------GGGFSASSLGG-GFGG------GSRGFGGASGGGYSSSGGFGGGFGG 116

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
             GG       SG    G  G  +   DG
Sbjct: 117 GSGGGFGGGYGSGFGGLGGFGGGAGGGDG 145



>gi|12643948|sp|Q9Y2N3|P121_HUMAN   Nuclear envelope pore membrane protein POM 121 (Pore membrane protein
            of 121 kDa) (P145)
          Length = 1229

 Score = 41.2 bits (95), Expect = 0.012
 Identities = 53/173 (30%), Positives = 68/173 (39%), Gaps = 35/173 (20%)

Query: 189  GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSL 248
            G   A F F  + S+ FG T          QT+SSG S S+  G T+    + F  GGS 
Sbjct: 1037 GGSTAVFSFGAATSSGFGAT---------TQTASSGSSSSV-FGSTT---PSPFTFGGSA 1083

Query: 249  NSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                    +G   FGIN        GS SA  G   FG+  S S   S  F  GLG+   
Sbjct: 1084 AP------AGSGSFGINV----ATPGS-SATTGAFSFGAGQSGSTATSTPFTGGLGQNAL 1132

Query: 309  GA-------EFNFRDSGSNQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
            G         FN   +  ++    G ++  F  N    GVG S +   F  SS
Sbjct: 1133 GTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 1185



>gi|182424|gb|AAA52426.1|   alpha-fibrinogen precursor
          Length = 644

 Score = 41.2 bits (95), Expect = 0.012
 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 28/298 (9%)

Query: 44  PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 98
           P   +E   PG  E         G+    ++P     AG + + SS  G +    P  S 
Sbjct: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313

Query: 99  GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
             G  G A  K G S             G +  GSS +G +  + P  S   G+TG    
Sbjct: 314 --GTGGTATWKPGSSGPGSA--------GSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362

Query: 159 KSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT--GISSKTVE 216
            S ER  AG+  SE S +  TG    + G+ + D+        +N    T   +S     
Sbjct: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +       +    GD   R+  + V  GS  +      S  +      IG +G    V
Sbjct: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRR---SCSKTVTKTVIGPDGHK-EV 478

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           + E      GSD   +++   L   G+G   G   F  R        D  ++ K F G
Sbjct: 479 TKEVVTSEDGSDCPEAMDLGTL--SGIGTLDG---FRHRHPDEAAFFDTASTGKTFPG 531



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           +SGS+  G  GN +    G G G ++ + G   SSG         GSS         TG 
Sbjct: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSAGSWNSGSSGT-----GSTGN 346

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
               S  P   G  +PGS    S G+  S  S SG  G+   E G
Sbjct: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 34/98 (34%), Positives = 39/98 (39%), Gaps = 8/98 (8%)

Query: 345 GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN-TW 403
           G E + G S   G   GS  +     S  G     SS P   GN +PGS  S +GG  TW
Sbjct: 266 GNEITRGGSTSYGT--GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGS--SGTGGTATW 321

Query: 404 SSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
               GS G G SA     G+SG    G         GS
Sbjct: 322 K--PGSSGPG-SAGSWNSGSSGTGSTGNQNPGSPRPGS 356



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 13/141 (9%)

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T+GG+  ++      +S  N +S+  ++    G  S  N    SSG    +    GSS  
Sbjct: 270 TRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                  +G +   S+     G+  PG   S    N  SS+ GS G   S   +      
Sbjct: 329 GSAGSWNSGSSGTGSTGNQNPGSPRPG---STGTWNPGSSERGSAGHWTSESSVS----- 380

Query: 426 LNEFGETGLSGSEKGSHIPEA 446
               G TG   SE GS  P++
Sbjct: 381 ----GSTGQWHSESGSFRPDS 397



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 373 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 426
           TG   +   +P  AG+ + GS    S GN     SG+GG      G       G   SG 
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSAGSWNSGS 338

Query: 427 NEFGETGLSGSEKGSHIPEAT 447
           +  G TG      GS  P +T
Sbjct: 339 SGTGSTG--NQNPGSPRPGST 357



>gi|51466314|ref|XP_499323.1|   PREDICTED: similar to Nuclear envelope pore membrane protein POM
           121 (Pore membrane protein of 121 kDa) (P145) [Homo
           sapiens]
 gi|51465952|ref|XP_496895.1|   PREDICTED: similar to Nuclear envelope pore membrane protein POM
           121 (Pore membrane protein of 121 kDa) (P145) [Homo
           sapiens]
          Length = 791

 Score = 40.8 bits (94), Expect = 0.016
 Identities = 53/173 (30%), Positives = 68/173 (39%), Gaps = 35/173 (20%)

Query: 189 GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSL 248
           G   A F F  + S+ FG T          QT+SSG S S+  G T+    + F  GGS 
Sbjct: 599 GGSTAVFSFGAATSSGFGAT---------TQTASSGSSSSV-FGSTT---PSPFTFGGSA 645

Query: 249 NSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKG 308
                   +G   FGIN        GS SA  G   FG+  S S   S  F  GLG+   
Sbjct: 646 AP------AGSGSFGINV----ATPGS-SATTGAFSFGAGQSGSTATSTPFAGGLGQNAL 694

Query: 309 GA-------EFNFRDSGSNQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
           G         FN   +  ++    G ++  F  N    GVG S +   F  SS
Sbjct: 695 GTTGQSTPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 747



>gi|71823|pir||FGHUA   fibrinogen alpha chain precursor, short splice form [validated] -
           human
 gi|4033511|gb|AAC97143.1|   fibrinogen alpha subunit [Homo sapiens]
 gi|11761629|ref|NP_068657.1|   fibrinogen, alpha chain isoform alpha preproprotein [Homo sapiens]
 gi|182426|gb|AAA52427.1|   A-alpha fibrinogen
 gi|458554|gb|AAA17055.1|   common fibrinogen alpha chain
          Length = 644

 Score = 40.8 bits (94), Expect = 0.016
 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 28/298 (9%)

Query: 44  PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 98
           P   +E   PG  E         G+    ++P     AG + + SS  G +    P  S 
Sbjct: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313

Query: 99  GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
             G  G A  K G S             G +  GSS +G +  + P  S   G+TG    
Sbjct: 314 --GTGGTATWKPGSSGPGS--------TGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362

Query: 159 KSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT--GISSKTVE 216
            S ER  AG+  SE S +  TG    + G+ + D+        +N    T   +S     
Sbjct: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +       +    GD   R+  + V  GS  +      S  +      IG +G    V
Sbjct: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRR---SCSKTVTKTVIGPDGHK-EV 478

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           + E      GSD   +++   L   G+G   G   F  R        D  ++ K F G
Sbjct: 479 TKEVVTSEDGSDCPEAMDLGTL--SGIGTLDG---FRHRHPDEAAFFDTASTGKTFPG 531



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           +SGS+  G  GN +    G G G ++ + G   SSG         GSS         TG 
Sbjct: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
               S  P   G  +PGS    S G+  S  S SG  G+   E G
Sbjct: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 13/141 (9%)

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T+GG+  ++      +S  N +S+  ++    G  S  N    SSG    +    GSS  
Sbjct: 270 TRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                  +G +   S+     G+  PG   S    N  SS+ GS G   S   +      
Sbjct: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPG---STGTWNPGSSERGSAGHWTSESSVS----- 380

Query: 426 LNEFGETGLSGSEKGSHIPEA 446
               G TG   SE GS  P++
Sbjct: 381 ----GSTGQWHSESGSFRPDS 397



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 373 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 426
           TG   +   +P  AG+ + GS    S GN     SG+GG      G       G   SG 
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338

Query: 427 NEFGETGLSGSEKGSHIPEAT 447
           +  G TG      GS  P +T
Sbjct: 339 SGTGSTG--NQNPGSPRPGST 357



>gi|40788304|dbj|BAA31593.2|   KIAA0618 protein [Homo sapiens]
          Length = 1052

 Score = 40.8 bits (94), Expect = 0.016
 Identities = 93/365 (25%), Positives = 136/365 (37%), Gaps = 67/365 (18%)

Query: 47   SLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKA 106
            SL    P  T   +      GS  +   PA    +S  +   S+ + P F++  G+  K+
Sbjct: 690  SLHTAVPTATSSSAADFSGFGSTLATSAPAT---SSQPTLTFSNTSTPTFNIPFGSSAKS 746

Query: 107  EDKS---GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGAT---GEDEDKS 160
               S    + Q A G+ +E  PPG               KP  +  FG++   G     +
Sbjct: 747  PLPSYPGANPQPAFGA-AEGQPPGA-------------AKPALAPSFGSSFTFGNSAAPA 792

Query: 161  RERWDAGNSRSEDSPA--------VGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT---- 208
                 A  S  +  PA        +  G++    G     +AFG   S   +FG +    
Sbjct: 793  AAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 852

Query: 209  ---GISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGIN 265
                 SS      QT+SSG S S+  G T+    + F  GGS         +G   FGIN
Sbjct: 853  FGAATSSGFGATTQTASSGSSSSV-FGSTT---PSPFTFGGSAAP------AGSGSFGIN 902

Query: 266  EIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGA-------EFNFRDSG 318
                    GS +    F  FG+  S S   S  F  GLG+   G         FN   + 
Sbjct: 903  V----ATPGSSTTTGAFS-FGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTT 957

Query: 319  SNQSGDNGNSSKDFDGN----GVGDSSARNGFENSSGISED-SGVI-LGSSDQHEVELS- 371
             ++    G ++  F  N    GVG S +   F  SS  ++   GV   G++  H+ E S 
Sbjct: 958  ESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAPFGNTFAHQQEHSP 1017

Query: 372  RTGGN 376
            R G N
Sbjct: 1018 RKGPN 1022



>gi|4503689|ref|NP_000499.1|   fibrinogen, alpha chain isoform alpha-E preproprotein [Homo
           sapiens]
 gi|13591824|gb|AAK31373.1|   fibrinogen alpha chain preproprotein, isoform alpha-E [Homo
           sapiens]
 gi|2135107|pir||D44234   fibrinogen alpha chain precursor, extended splice form - human
 gi|182407|gb|AAC97142.1|   fibrinogen alpha subunit precursor [Homo sapiens]
 gi|1706799|sp|P02671|FIBA_HUMAN   Fibrinogen alpha/alpha-E chain precursor [Contains: Fibrinopeptide
           A]
 gi|458555|gb|AAA17056.1|   fibrinogen alpha-E chain
          Length = 866

 Score = 40.8 bits (94), Expect = 0.016
 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 28/298 (9%)

Query: 44  PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 98
           P   +E   PG  E         G+    ++P     AG + + SS  G +    P  S 
Sbjct: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313

Query: 99  GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
             G  G A  K G S             G +  GSS +G +  + P  S   G+TG    
Sbjct: 314 --GTGGTATWKPGSSGPGS--------TGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362

Query: 159 KSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT--GISSKTVE 216
            S ER  AG+  SE S +  TG    + G+ + D+        +N    T   +S     
Sbjct: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +       +    GD   R+  + V  GS  +      S  +      IG +G    V
Sbjct: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRR---SCSKTVTKTVIGPDGHK-EV 478

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           + E      GSD   +++   L   G+G   G   F  R        D  ++ K F G
Sbjct: 479 TKEVVTSEDGSDCPEAMDLGTL--SGIGTLDG---FRHRHPDEAAFFDTASTGKTFPG 531



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           +SGS+  G  GN +    G G G ++ + G   SSG         GSS         TG 
Sbjct: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
               S  P   G  +PGS    S G+  S  S SG  G+   E G
Sbjct: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 13/141 (9%)

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T+GG+  ++      +S  N +S+  ++    G  S  N    SSG    +    GSS  
Sbjct: 270 TRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                  +G +   S+     G+  PG   S    N  SS+ GS G   S   +      
Sbjct: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPG---STGTWNPGSSERGSAGHWTSESSVS----- 380

Query: 426 LNEFGETGLSGSEKGSHIPEA 446
               G TG   SE GS  P++
Sbjct: 381 ----GSTGQWHSESGSFRPDS 397



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 373 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 426
           TG   +   +P  AG+ + GS    S GN     SG+GG      G       G   SG 
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338

Query: 427 NEFGETGLSGSEKGSHIPEAT 447
           +  G TG      GS  P +T
Sbjct: 339 SGTGSTG--NQNPGSPRPGST 357



>gi|13591823|gb|AAK31372.1|   fibrinogen alpha chain preproprotein, isoform alpha [Homo sapiens]
          Length = 647

 Score = 40.8 bits (94), Expect = 0.016
 Identities = 71/298 (23%), Positives = 105/298 (35%), Gaps = 28/298 (9%)

Query: 44  PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 98
           P   +E   PG  E         G+    ++P     AG + + SS  G +    P  S 
Sbjct: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313

Query: 99  GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
             G  G A  K G S             G +  GSS +G +  + P  S   G+TG    
Sbjct: 314 --GTGGTATWKPGSSGPGS--------TGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362

Query: 159 KSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT--GISSKTVE 216
            S ER  AG+  SE S +  TG    + G+ + D+        +N    T   +S     
Sbjct: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G +       +    GD   R+  + V  GS  +      S  +      IG +G    V
Sbjct: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRR---SCSKTVTKTVIGPDGHK-EV 478

Query: 277 SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           + E      GSD   +++   L   G+G   G   F  R        D  ++ K F G
Sbjct: 479 TKEVVTSEDGSDCPEAMDLGTL--SGIGTLDG---FRHRHPDEAAFFDTASTGKTFPG 531



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 9/105 (8%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           +SGS+  G  GN +    G G G ++ + G   SSG         GSS         TG 
Sbjct: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
               S  P   G  +PGS    S G+  S  S SG  G+   E G
Sbjct: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 13/141 (9%)

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T+GG+  ++      +S  N +S+  ++    G  S  N    SSG    +    GSS  
Sbjct: 270 TRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                  +G +   S+     G+  PG   S    N  SS+ GS G   S   +      
Sbjct: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPG---STGTWNPGSSERGSAGHWTSESSVS----- 380

Query: 426 LNEFGETGLSGSEKGSHIPEA 446
               G TG   SE GS  P++
Sbjct: 381 ----GSTGQWHSESGSFRPDS 397



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 8/81 (9%)

Query: 373 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 426
           TG   +   +P  AG+ + GS    S GN     SG+GG      G       G   SG 
Sbjct: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338

Query: 427 NEFGETGLSGSEKGSHIPEAT 447
           +  G TG      GS  P +T
Sbjct: 339 SGTGSTG--NQNPGSPRPGST 357



>gi|2136324|pir||I38488   trophinin - human
          Length = 749

 Score = 40.4 bits (93), Expect = 0.021
 Identities = 103/434 (23%), Positives = 155/434 (35%), Gaps = 61/434 (14%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
           GSP S  +  GG  ++S   G S  T   F   L         S  S + GG+ S     
Sbjct: 219 GSPSSSGS-FGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSI-- 275

Query: 127 GGFFYGSSSSGDSDKKKPLFSFEFGA-----TGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
              F GS S+G         S  FG+     TG     S    D G + S      G+  
Sbjct: 276 --CFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSA-DFGGTLSTSVCFGGSPG 332

Query: 182 SGLKLGAGKG-DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT---SFR 237
           + +  G+    +A +G  VS +  FG T  +S    G+ ++S+G   +++   +   +  
Sbjct: 333 TSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVS 392

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFK-------GFGSDSS 290
           +   F G  S ++  +       GFG       G  G++S  A F        GFG+  S
Sbjct: 393 TSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPS 452

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-----GDNGNSSKDFDG----NGVGDSS 341
           +SV  S+    G     GGA       GS  +     G   ++S  F G    +     S
Sbjct: 453 TSV--SFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPS 510

Query: 342 ARNGFENSSGISEDSGV------------ILGSSDQHEVELSRTGG-------NRKRSSD 382
              GF   +G+S ++G              LG+S      LS + G       +      
Sbjct: 511 TSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGG 570

Query: 383 PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGET---------G 433
           P  +     G   S        + +G GGG  ++D  G G      FG T         G
Sbjct: 571 PGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGG 630

Query: 434 LSGSEKGSHIPEAT 447
           LS S+     P A+
Sbjct: 631 LSTSDGFGSRPNAS 644



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 63/243 (25%), Positives = 85/243 (34%), Gaps = 38/243 (15%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
           G+  S +   GG  N+S+  G    T   FS GL      +   G S   GG     T  
Sbjct: 518 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 577

Query: 127 GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSS-GLK 185
           GG     +S+G S        F  G    D                    +GT +S G  
Sbjct: 578 GGGL--GTSAGFSGGLGTSAGFGGGLVTSDGFGG---------------GLGTNASFGST 620

Query: 186 LGAGKGDAAFGFEVSDSNSFG-------DTGISSKTVEGNQTSSSGGSVSIDLGDTSFRS 238
           LG   G   F   +S S+ FG       D G+S+    G+ +++S G        T F S
Sbjct: 621 LGTSAG---FSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSS 677

Query: 239 -ENQFVG--GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSD 288
             +  VG  GG    +         GF      G G  G  +  AGF        GFGS 
Sbjct: 678 GPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG 737

Query: 289 SSS 291
           ++S
Sbjct: 738 AAS 740



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 86/380 (22%), Positives = 136/380 (35%), Gaps = 61/380 (16%)

Query: 57  EDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA 116
           E ++R +++A +  + +   G    +S+ +G SDR    F+   GAP  +   SG     
Sbjct: 24  EIEARAQENADASTNVNFSRG----ASTRAGFSDRASISFN---GAPSSSGGFSGG---- 72

Query: 117 GGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPA 176
                    PG  F  + S+  S       S  FG T                 +  +  
Sbjct: 73  ---------PGITFGVAPSTSASFSNTA--SISFGGTLSTSSSFSSAASISFGCAHSTST 121

Query: 177 VGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSF 236
             +  + +  G G    +  F    S+SF     +S T  G  +S  GG++S   G +  
Sbjct: 122 SFSSEASISFG-GMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGV 180

Query: 237 RSENQFVGGG-SLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-------FGSD 288
            S +   G   + +++ +   S   GFG          GS S+   F G       FG  
Sbjct: 181 LSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGS 240

Query: 289 SSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFEN 348
             +S        FG G       F    S S   G   ++S  FDG+     S   GF  
Sbjct: 241 PCTST------GFG-GTLSTSVSFGGSSSTSANFGGTLSTSICFDGS----PSTGAGFGG 289

Query: 349 SSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNL--------SPGSDVSDSGG 400
           +   S   G +L +S         TG     S+  D  G L        SPG+ V  S G
Sbjct: 290 ALNTSASFGSVLNTS---------TGFGGAMSTSADFGGTLSTSVCFGGSPGTSV--SFG 338

Query: 401 NTWSSDSGSGGGGKSADELG 420
           +  ++++G GG   +  + G
Sbjct: 339 SALNTNAGYGGAVSTNTDFG 358



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 79/335 (23%), Positives = 112/335 (33%), Gaps = 76/335 (22%)

Query: 77  GGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDA----GGSKSEDTPP 126
           GG F++S+  G +  T   F      S+G GA        G +       GG+     P 
Sbjct: 418 GGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGA-----PS 472

Query: 127 GGFFYGSSSS-----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
               +GS+S+     G        FS     +  D   +   +  GN  S ++   G  +
Sbjct: 473 TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLN 532

Query: 182 SGLKLGAGKGDAA-FGFEVSDSNSF-GDTGISSKTVEGNQTSSS-GGSVSIDLGDTSFRS 238
           +    G G G +A F   +S S+ F G  G S+    G  TS+  GG +    G +    
Sbjct: 533 TSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLG 592

Query: 239 ENQFVGGGSLNSISNLWDSGQEGFGINEIGGN------GMSGSVSAEAGF---------- 282
            +   GGG + S     D    G G N   G+      G SG +S   GF          
Sbjct: 593 TSAGFGGGLVTS-----DGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR 647

Query: 283 -------------------------KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                                     GF S  SS V  S     G+G   G +   F   
Sbjct: 648 GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGG 707

Query: 318 GSNQSGDNG--NSSKDFDGN-----GVGDSSARNG 345
            S  +G  G  N+   F G      G G  +A  G
Sbjct: 708 PSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 742



>gi|7529568|emb|CAB86651.1|   trophinin [Homo sapiens]
 gi|17380567|sp|Q12816|TROP_HUMAN   Trophinin (MAGE-D3 antigen)
          Length = 1387

 Score = 40.4 bits (93), Expect = 0.021
 Identities = 103/434 (23%), Positives = 155/434 (35%), Gaps = 61/434 (14%)

Query: 67   GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
            GSP S  +  GG  ++S   G S  T   F   L         S  S + GG+ S     
Sbjct: 857  GSPSSSGS-FGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSI-- 913

Query: 127  GGFFYGSSSSGDSDKKKPLFSFEFGA-----TGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
               F GS S+G         S  FG+     TG     S    D G + S      G+  
Sbjct: 914  --CFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSA-DFGGTLSTSVCFGGSPG 970

Query: 182  SGLKLGAGKG-DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT---SFR 237
            + +  G+    +A +G  VS +  FG T  +S    G+ ++S+G   +++   +   +  
Sbjct: 971  TSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVS 1030

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFK-------GFGSDSS 290
            +   F G  S ++  +       GFG       G  G++S  A F        GFG+  S
Sbjct: 1031 TSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPS 1090

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-----GDNGNSSKDFDG----NGVGDSS 341
            +SV  S+    G     GGA       GS  +     G   ++S  F G    +     S
Sbjct: 1091 TSV--SFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPS 1148

Query: 342  ARNGFENSSGISEDSGV------------ILGSSDQHEVELSRTGG-------NRKRSSD 382
               GF   +G+S ++G              LG+S      LS + G       +      
Sbjct: 1149 TSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGG 1208

Query: 383  PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGET---------G 433
            P  +     G   S        + +G GGG  ++D  G G      FG T         G
Sbjct: 1209 PGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGG 1268

Query: 434  LSGSEKGSHIPEAT 447
            LS S+     P A+
Sbjct: 1269 LSTSDGFGSRPNAS 1282



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 102/451 (22%), Positives = 150/451 (33%), Gaps = 84/451 (18%)

Query: 22   AASRSGGFSYGSSSS-GDLDRKKPLFS----LEFGSPGETEDKSRQRQDAGSPKSEDTPA 76
            A S SGGFS G   + G        FS    + FG    T              +  T  
Sbjct: 700  APSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTST 759

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAP------GKAEDKSGDSQDAGGSKSEDTPPGGFF 130
                 +S S G    T   FS G+ +         A    G S   GG+ S      G  
Sbjct: 760  SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVL 819

Query: 131  YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
              S+S G +     +FS                          + +  TG  G+      
Sbjct: 820  STSTSFGSAPTTSTVFS-------------------------SALSTSTGFGGIL----S 850

Query: 191  GDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG----SVSIDLGDTSFRSENQFVGGG 246
                FG   S S SFG T  +S    G+  +S+G     S S+  G +S  S N    GG
Sbjct: 851  TSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSAN---FGG 907

Query: 247  SLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSDSSSSVEKSWLF 299
            +L S S  +D            G G  G+++  A F        GFG   S+S +     
Sbjct: 908  TL-STSICFDGSPS-------TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTL 959

Query: 300  E----FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
                 FG      G   +F  + +  +G  G  S + D  G   +S    F  S   S  
Sbjct: 960  STSVCFG---GSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSV--CFGGSPSTSAG 1014

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG-GNTWSSDSGSGG--- 411
             G  L ++      +S +       S          G+ +++ G G  +S+ +G GG   
Sbjct: 1015 FGGALNTNASFGCAVSTSAS----FSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALS 1070

Query: 412  -----GGKSADELGVGASGLNEFGETGLSGS 437
                 GG  ++ +G GA+        G  G+
Sbjct: 1071 TAADFGGTPSNSIGFGAAPSTSVSFGGAHGT 1101



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 63/243 (25%), Positives = 85/243 (34%), Gaps = 38/243 (15%)

Query: 67   GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
            G+  S +   GG  N+S+  G    T   FS GL      +   G S   GG     T  
Sbjct: 1156 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 1215

Query: 127  GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSS-GLK 185
            GG     +S+G S        F  G    D                    +GT +S G  
Sbjct: 1216 GGGL--GTSAGFSGGLGTSAGFGGGLVTSDGFGG---------------GLGTNASFGST 1258

Query: 186  LGAGKGDAAFGFEVSDSNSFG-------DTGISSKTVEGNQTSSSGGSVSIDLGDTSFRS 238
            LG   G   F   +S S+ FG       D G+S+    G+ +++S G        T F S
Sbjct: 1259 LGTSAG---FSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSS 1315

Query: 239  -ENQFVG--GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSD 288
              +  VG  GG    +         GF      G G  G  +  AGF        GFGS 
Sbjct: 1316 GPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG 1375

Query: 289  SSS 291
            ++S
Sbjct: 1376 AAS 1378



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 79/335 (23%), Positives = 112/335 (33%), Gaps = 76/335 (22%)

Query: 77   GGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDA----GGSKSEDTPP 126
            GG F++S+  G +  T   F      S+G GA        G +       GG+     P 
Sbjct: 1056 GGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGA-----PS 1110

Query: 127  GGFFYGSSSS-----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
                +GS+S+     G        FS     +  D   +   +  GN  S ++   G  +
Sbjct: 1111 TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLN 1170

Query: 182  SGLKLGAGKGDAA-FGFEVSDSNSF-GDTGISSKTVEGNQTSSS-GGSVSIDLGDTSFRS 238
            +    G G G +A F   +S S+ F G  G S+    G  TS+  GG +    G +    
Sbjct: 1171 TSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLG 1230

Query: 239  ENQFVGGGSLNSISNLWDSGQEGFGINEIGGN------GMSGSVSAEAGF---------- 282
             +   GGG + S     D    G G N   G+      G SG +S   GF          
Sbjct: 1231 TSAGFGGGLVTS-----DGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR 1285

Query: 283  -------------------------KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                                      GF S  SS V  S     G+G   G +   F   
Sbjct: 1286 GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGG 1345

Query: 318  GSNQSGDNG--NSSKDFDGN-----GVGDSSARNG 345
             S  +G  G  N+   F G      G G  +A  G
Sbjct: 1346 PSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 1380



>gi|33304374|gb|AAA79334.2|   trophinin [Homo sapiens]
          Length = 749

 Score = 40.4 bits (93), Expect = 0.021
 Identities = 103/434 (23%), Positives = 155/434 (35%), Gaps = 61/434 (14%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
           GSP S  +  GG  ++S   G S  T   F   L         S  S + GG+ S     
Sbjct: 219 GSPSSSGS-FGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSI-- 275

Query: 127 GGFFYGSSSSGDSDKKKPLFSFEFGA-----TGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
              F GS S+G         S  FG+     TG     S    D G + S      G+  
Sbjct: 276 --CFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSA-DFGGTLSTSVCFGGSPG 332

Query: 182 SGLKLGAGKG-DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT---SFR 237
           + +  G+    +A +G  VS +  FG T  +S    G+ ++S+G   +++   +   +  
Sbjct: 333 TSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVS 392

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFK-------GFGSDSS 290
           +   F G  S ++  +       GFG       G  G++S  A F        GFG+  S
Sbjct: 393 TSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPS 452

Query: 291 SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-----GDNGNSSKDFDG----NGVGDSS 341
           +SV  S+    G     GGA       GS  +     G   ++S  F G    +     S
Sbjct: 453 TSV--SFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPS 510

Query: 342 ARNGFENSSGISEDSGV------------ILGSSDQHEVELSRTGG-------NRKRSSD 382
              GF   +G+S ++G              LG+S      LS + G       +      
Sbjct: 511 TSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGG 570

Query: 383 PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGET---------G 433
           P  +     G   S        + +G GGG  ++D  G G      FG T         G
Sbjct: 571 PGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGG 630

Query: 434 LSGSEKGSHIPEAT 447
           LS S+     P A+
Sbjct: 631 LSTSDGFGSRPNAS 644



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 102/451 (22%), Positives = 150/451 (33%), Gaps = 84/451 (18%)

Query: 22  AASRSGGFSYGSSSS-GDLDRKKPLFS----LEFGSPGETEDKSRQRQDAGSPKSEDTPA 76
           A S SGGFS G   + G        FS    + FG    T              +  T  
Sbjct: 62  APSTSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTST 121

Query: 77  GGFFNSSSSSGDSDRTKPFFSLGLGAP------GKAEDKSGDSQDAGGSKSEDTPPGGFF 130
                +S S G    T   FS G+ +         A    G S   GG+ S      G  
Sbjct: 122 SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVL 181

Query: 131 YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
             S+S G +     +FS                          + +  TG  G+      
Sbjct: 182 STSTSFGSAPTTSTVFS-------------------------SALSTSTGFGGIL----S 212

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG----SVSIDLGDTSFRSENQFVGGG 246
               FG   S S SFG T  +S    G+  +S+G     S S+  G +S  S N    GG
Sbjct: 213 TSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSAN---FGG 269

Query: 247 SLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSDSSSSVEKSWLF 299
           +L S S  +D            G G  G+++  A F        GFG   S+S +     
Sbjct: 270 TL-STSICFDGSPS-------TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTL 321

Query: 300 E----FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
                FG      G   +F  + +  +G  G  S + D  G   +S    F  S   S  
Sbjct: 322 STSVCFG---GSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSV--CFGGSPSTSAG 376

Query: 356 SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG-GNTWSSDSGSGG--- 411
            G  L ++      +S +       S          G+ +++ G G  +S+ +G GG   
Sbjct: 377 FGGALNTNASFGCAVSTSAS----FSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALS 432

Query: 412 -----GGKSADELGVGASGLNEFGETGLSGS 437
                GG  ++ +G GA+        G  G+
Sbjct: 433 TAADFGGTPSNSIGFGAAPSTSVSFGGAHGT 463



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 63/243 (25%), Positives = 85/243 (34%), Gaps = 38/243 (15%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
           G+  S +   GG  N+S+  G    T   FS GL      +   G S   GG     T  
Sbjct: 518 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 577

Query: 127 GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSS-GLK 185
           GG     +S+G S        F  G    D                    +GT +S G  
Sbjct: 578 GGGL--GTSAGFSGGLGTSAGFGGGLVTSDGFGG---------------GLGTNASFGST 620

Query: 186 LGAGKGDAAFGFEVSDSNSFG-------DTGISSKTVEGNQTSSSGGSVSIDLGDTSFRS 238
           LG   G   F   +S S+ FG       D G+S+    G+ +++S G        T F S
Sbjct: 621 LGTSAG---FSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSS 677

Query: 239 -ENQFVG--GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSD 288
             +  VG  GG    +         GF      G G  G  +  AGF        GFGS 
Sbjct: 678 GPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG 737

Query: 289 SSS 291
           ++S
Sbjct: 738 AAS 740



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 79/335 (23%), Positives = 112/335 (33%), Gaps = 76/335 (22%)

Query: 77  GGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDA----GGSKSEDTPP 126
           GG F++S+  G +  T   F      S+G GA        G +       GG+     P 
Sbjct: 418 GGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGA-----PS 472

Query: 127 GGFFYGSSSS-----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
               +GS+S+     G        FS     +  D   +   +  GN  S ++   G  +
Sbjct: 473 TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLN 532

Query: 182 SGLKLGAGKGDAA-FGFEVSDSNSF-GDTGISSKTVEGNQTSSS-GGSVSIDLGDTSFRS 238
           +    G G G +A F   +S S+ F G  G S+    G  TS+  GG +    G +    
Sbjct: 533 TSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLG 592

Query: 239 ENQFVGGGSLNSISNLWDSGQEGFGINEIGGN------GMSGSVSAEAGF---------- 282
            +   GGG + S     D    G G N   G+      G SG +S   GF          
Sbjct: 593 TSAGFGGGLVTS-----DGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR 647

Query: 283 -------------------------KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                                     GF S  SS V  S     G+G   G +   F   
Sbjct: 648 GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGG 707

Query: 318 GSNQSGDNG--NSSKDFDGN-----GVGDSSARNG 345
            S  +G  G  N+   F G      G G  +A  G
Sbjct: 708 PSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 742



>gi|58257678|dbj|BAA83066.3|   KIAA1114 protein [Homo sapiens]
          Length = 1458

 Score = 40.4 bits (93), Expect = 0.021
 Identities = 103/434 (23%), Positives = 155/434 (35%), Gaps = 61/434 (14%)

Query: 67   GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
            GSP S  +  GG  ++S   G S  T   F   L         S  S + GG+ S     
Sbjct: 928  GSPSSSGS-FGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSI-- 984

Query: 127  GGFFYGSSSSGDSDKKKPLFSFEFGA-----TGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
               F GS S+G         S  FG+     TG     S    D G + S      G+  
Sbjct: 985  --CFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSA-DFGGTLSTSVCFGGSPG 1041

Query: 182  SGLKLGAGKG-DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDT---SFR 237
            + +  G+    +A +G  VS +  FG T  +S    G+ ++S+G   +++   +   +  
Sbjct: 1042 TSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVS 1101

Query: 238  SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFK-------GFGSDSS 290
            +   F G  S ++  +       GFG       G  G++S  A F        GFG+  S
Sbjct: 1102 TSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPS 1161

Query: 291  SSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS-----GDNGNSSKDFDG----NGVGDSS 341
            +SV  S+    G     GGA       GS  +     G   ++S  F G    +     S
Sbjct: 1162 TSV--SFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPS 1219

Query: 342  ARNGFENSSGISEDSGV------------ILGSSDQHEVELSRTGG-------NRKRSSD 382
               GF   +G+S ++G              LG+S      LS + G       +      
Sbjct: 1220 TSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGG 1279

Query: 383  PDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGET---------G 433
            P  +     G   S        + +G GGG  ++D  G G      FG T         G
Sbjct: 1280 PGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGG 1339

Query: 434  LSGSEKGSHIPEAT 447
            LS S+     P A+
Sbjct: 1340 LSTSDGFGSRPNAS 1353



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 102/451 (22%), Positives = 150/451 (33%), Gaps = 84/451 (18%)

Query: 22   AASRSGGFSYGSSSS-GDLDRKKPLFS----LEFGSPGETEDKSRQRQDAGSPKSEDTPA 76
            A S SGGFS G   + G        FS    + FG    T              +  T  
Sbjct: 771  APSSSGGFSGGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTST 830

Query: 77   GGFFNSSSSSGDSDRTKPFFSLGLGAP------GKAEDKSGDSQDAGGSKSEDTPPGGFF 130
                 +S S G    T   FS G+ +         A    G S   GG+ S      G  
Sbjct: 831  SFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVL 890

Query: 131  YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
              S+S G +     +FS                          + +  TG  G+      
Sbjct: 891  STSTSFGSAPTTSTVFS-------------------------SALSTSTGFGGIL----S 921

Query: 191  GDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG----SVSIDLGDTSFRSENQFVGGG 246
                FG   S S SFG T  +S    G+  +S+G     S S+  G +S  S N    GG
Sbjct: 922  TSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSAN---FGG 978

Query: 247  SLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSDSSSSVEKSWLF 299
            +L S S  +D            G G  G+++  A F        GFG   S+S +     
Sbjct: 979  TL-STSICFDGSPS-------TGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTL 1030

Query: 300  E----FGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISED 355
                 FG      G   +F  + +  +G  G  S + D  G   +S    F  S   S  
Sbjct: 1031 STSVCFG---GSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSV--CFGGSPSTSAG 1085

Query: 356  SGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG-GNTWSSDSGSGG--- 411
             G  L ++      +S +       S          G+ +++ G G  +S+ +G GG   
Sbjct: 1086 FGGALNTNASFGCAVSTSAS----FSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALS 1141

Query: 412  -----GGKSADELGVGASGLNEFGETGLSGS 437
                 GG  ++ +G GA+        G  G+
Sbjct: 1142 TAADFGGTPSNSIGFGAAPSTSVSFGGAHGT 1172



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 63/243 (25%), Positives = 85/243 (34%), Gaps = 38/243 (15%)

Query: 67   GSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPP 126
            G+  S +   GG  N+S+  G    T   FS GL      +   G S   GG     T  
Sbjct: 1227 GNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGF 1286

Query: 127  GGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSS-GLK 185
            GG     +S+G S        F  G    D                    +GT +S G  
Sbjct: 1287 GGGL--GTSAGFSGGLGTSAGFGGGLVTSDGFGG---------------GLGTNASFGST 1329

Query: 186  LGAGKGDAAFGFEVSDSNSFG-------DTGISSKTVEGNQTSSSGGSVSIDLGDTSFRS 238
            LG   G   F   +S S+ FG       D G+S+    G+ +++S G        T F S
Sbjct: 1330 LGTSAG---FSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSS 1386

Query: 239  -ENQFVG--GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGF-------KGFGSD 288
              +  VG  GG    +         GF      G G  G  +  AGF        GFGS 
Sbjct: 1387 GPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAGFGSG 1446

Query: 289  SSS 291
            ++S
Sbjct: 1447 AAS 1449



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 79/335 (23%), Positives = 112/335 (33%), Gaps = 76/335 (22%)

Query: 77   GGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDA----GGSKSEDTPP 126
            GG F++S+  G +  T   F      S+G GA        G +       GG+     P 
Sbjct: 1127 GGAFSTSAGFGGALSTAADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGA-----PS 1181

Query: 127  GGFFYGSSSS-----GDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGS 181
                +GS+S+     G        FS     +  D   +   +  GN  S ++   G  +
Sbjct: 1182 TSLCFGSASNTNLCFGGPPSTSACFSGATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLN 1241

Query: 182  SGLKLGAGKGDAA-FGFEVSDSNSF-GDTGISSKTVEGNQTSSS-GGSVSIDLGDTSFRS 238
            +    G G G +A F   +S S+ F G  G S+    G  TS+  GG +    G +    
Sbjct: 1242 TSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLG 1301

Query: 239  ENQFVGGGSLNSISNLWDSGQEGFGINEIGGN------GMSGSVSAEAGF---------- 282
             +   GGG + S     D    G G N   G+      G SG +S   GF          
Sbjct: 1302 TSAGFGGGLVTS-----DGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDR 1356

Query: 283  -------------------------KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDS 317
                                      GF S  SS V  S     G+G   G +   F   
Sbjct: 1357 GLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGG 1416

Query: 318  GSNQSGDNG--NSSKDFDGN-----GVGDSSARNG 345
             S  +G  G  N+   F G      G G  +A  G
Sbjct: 1417 PSTGAGFGGGPNTGAGFGGGPSTSAGFGSGAASLG 1451



>gi|26051278|ref|NP_742017.1|   nuclear pore membrane protein 121 [Homo sapiens]
 gi|14250658|gb|AAH08794.1|   Nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 40.0 bits (92), Expect = 0.028
 Identities = 84/336 (25%), Positives = 122/336 (36%), Gaps = 64/336 (19%)

Query: 47  SLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKA 106
           SL    P  T   +      GS  +   PA    +S  +   S+ + P F++  G+  K+
Sbjct: 637 SLHTAVPTATSSSAADFSGFGSTLATSAPAT---SSQPTLTFSNTSTPTFNIPFGSSAKS 693

Query: 107 EDKS---GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGAT---GEDEDKS 160
              S    + Q A G+ +E  PPG               KP  +  FG++   G     +
Sbjct: 694 PLPSYPGANPQPAFGA-AEGQPPGA-------------AKPALAPSFGSSFTFGNSAAPA 739

Query: 161 RERWDAGNSRSEDSPA--------VGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT---- 208
                A  S  +  PA        +  G++    G     +AFG   S   +FG +    
Sbjct: 740 AAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVF 799

Query: 209 ---GISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGIN 265
                SS      QT+SSG S S+  G T+    + F  GGS         +G   FGIN
Sbjct: 800 FGAATSSGFGATTQTASSGSSSSV-FGSTT---PSPFTFGGSAAP------AGSGSFGIN 849

Query: 266 EIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGA-------EFNFRDSG 318
                   GS +    F  FG+  S S   S  F  GLG+   G         FN   + 
Sbjct: 850 V----ATPGSSTTTGAFS-FGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTT 904

Query: 319 SNQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
            ++    G ++  F  N    GVG S +   F  SS
Sbjct: 905 ESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 940



>gi|37182908|gb|AAQ89254.1|   MATN2 [Homo sapiens]
          Length = 915

 Score = 40.0 bits (92), Expect = 0.028
 Identities = 50/246 (20%), Positives = 95/246 (38%), Gaps = 35/246 (14%)

Query: 647 VGLCGSYNNKAEDDFMSSQ-NILEKTSQAFANSWEMMSCPK---------GNPSSCISIE 696
           V  C S N+  E + +++  + L +  + FA + +  +C +         G    C+++E
Sbjct: 321 VDYCASENHGCEHECVNADGSYLCQCHEGFALNPDEKTCTRINYCALNKPGCEHECVNME 380

Query: 697 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYV 753
           +  +   H G  LD +G   +C  + +       C++     E+S  C C+   ++   +
Sbjct: 381 ESYYCRCHRGYTLDPNG--KTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDL 438

Query: 754 KACAEKETYIVGWRTGLCEHS-----------CPSGLVFKYNVKACNSSCRSLSERDRSC 802
           K C+  +  ++      CE+S           CP G V + + K C +   S +  D  C
Sbjct: 439 KTCSRVDYCLLSDHG--CEYSCVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGC 495

Query: 803 DVEDVPVDG---CTCPDAMYQNNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRD 858
           +   V  +    C C +      +G  C  K  C     D   +   +   D   C C +
Sbjct: 496 EHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLE 553

Query: 859 GILLCQ 864
           G  L +
Sbjct: 554 GFRLAE 559



>gi|51470788|ref|XP_495860.1|   PREDICTED: apomucin [Homo sapiens]
          Length = 477

 Score = 40.0 bits (92), Expect = 0.028
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 10/92 (10%)

Query: 526 DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATC--- 582
           D    C +    + LCAS        WR  +  +C    CP   +Y+ CGPSNP+ C   
Sbjct: 3   DLDVVCSSLELYAALCASHD--ICIDWRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGN 59

Query: 583 ---SNVAPFQDSECVSGCTCPEDKIQIFNASS 611
              S  A  +      GC CPE  + +F+ S+
Sbjct: 60  DSASLGALPEAGPITEGCFCPEG-MTLFSTSA 90



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 15/56 (26%), Positives = 26/56 (46%), Gaps = 9/56 (16%)

Query: 1077 CTAVAMYAEACSAVGVCVSW--RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1130
            C+++ +YA  C++  +C+ W  R  ++CP  C            Y+PCG      C
Sbjct: 8    CSSLELYAALCASHDICIDWRGRTGHMCPFTCPADKV-------YQPCGPSNPSYC 56



>gi|34327775|gb|AAQ63629.1|   heterogeneous nuclear ribonucleoprotein A3 [Homo sapiens]
 gi|34740329|ref|NP_919223.1|   heterogeneous nuclear ribonucleoprotein A3 [Homo sapiens]
 gi|51338779|sp|P51991|ROA3_HUMAN   Heterogeneous nuclear ribonucleoprotein A3 (hnRNP A3)
          Length = 378

 Score = 39.7 bits (91), Expect = 0.036
 Identities = 51/197 (25%), Positives = 70/197 (35%), Gaps = 30/197 (15%)

Query: 161 RERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQT 220
           +E   AG+ R         G SG  +G G      G       +FG  G       G++ 
Sbjct: 205 QEMQSAGSQRGRG------GGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRG 258

Query: 221 SSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA 280
           S  GG    D G   F  +    GGG   S    +  G  G+G N+ GG G  G      
Sbjct: 259 SYGGG----DGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYG-NQGGGYGGGG------ 307

Query: 281 GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
           G+ G+    +          FG G   GG   N+ D G N SG   ++     G   G  
Sbjct: 308 GYDGYNEGGN----------FGGGNYGGGG--NYNDFG-NYSGQQQSNYGPMKGGSFGGR 354

Query: 341 SARNGFENSSGISEDSG 357
           S+ + +    G    SG
Sbjct: 355 SSGSPYGGGYGSGGGSG 371



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 39/159 (24%), Positives = 50/159 (31%), Gaps = 34/159 (21%)

Query: 284 GFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSAR 343
           G   +   ++ K  +   G    +GG   NF   G N  G  GN  +       G+   R
Sbjct: 193 GHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG------GNFGGR 246

Query: 344 NGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTW 403
            G+    G S  S    G  D         GGN                      GG  +
Sbjct: 247 GGYGGGGGGSRGS---YGGGDGGYNGFGGDGGNY--------------------GGGPGY 283

Query: 404 SSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           SS  G GGGG      G G  G    G  G  G  +G +
Sbjct: 284 SSRGGYGGGGP-----GYGNQGGGYGGGGGYDGYNEGGN 317



>gi|1709063|sp|Q10571|MN1_HUMAN   Probable tumor suppressor protein MN1
          Length = 1319

 Score = 39.7 bits (91), Expect = 0.036
 Identities = 84/339 (24%), Positives = 115/339 (33%), Gaps = 63/339 (18%)

Query: 96  FSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGE 155
           F   LG  G+ +   G       + SE  PP   F  S+  G          F FGA G 
Sbjct: 701 FGGSLGGLGQLQSP-GAGVGLPSAASERRPPPPDFATSALGGQP-------GFPFGAAGR 752

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
                          S  S   G GSSG   G G       F+ S   S    G  S   
Sbjct: 753 QSTPH----SGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGS 808

Query: 216 EGNQTSSSG--GSVSIDLGDTSFRSENQFVGGGSLNSISNLWD--SGQEGFGINEIGGNG 271
               +S     G   +    T+ ++    +G  +LN   N  +   G+     NE  G  
Sbjct: 809 FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAA 868

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           ++G+          GSD            +  G T  G     R SG++ SG   +   +
Sbjct: 869 VAGNP---------GSD------------YFPGGTAPGGPRTRRPSGTSSSGSKASGPPN 907

Query: 332 FDGNGVGDSSARN-GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G G S + N   E++SG   D   + G            GG R R     ++G++S
Sbjct: 908 PPAQGDGTSLSPNYTLESTSG--NDGKPVSG------------GGGRGRGRRKRDSGHVS 953

Query: 391 PG------SDVSDSGGNTWSSD-----SGSGGGGKSADE 418
           PG      S   DSGG    S      SG+  GG SA E
Sbjct: 954 PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGE 992



>gi|14043070|ref|NP_112420.1|   heterogeneous nuclear ribonucleoprotein A1 isoform b [Homo sapiens]
          Length = 372

 Score = 38.9 bits (89), Expect = 0.061
 Identities = 50/190 (26%), Positives = 69/190 (36%), Gaps = 32/190 (16%)

Query: 257 SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRD 316
           SG   FG    GG G + +      F G G               G G ++GG  +    
Sbjct: 197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRG---------------GFGGSRGGGGYGGSG 241

Query: 317 SGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
            G N  G++G     + G G G S    G+ +      + G   G S  ++   +  GG 
Sbjct: 242 DGYNGFGNDGG----YGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGG 297

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGG-NTWSSDSG--SGG--GGKSADELGVG----ASGLN 427
               S      N   G   +D G  N  SS+ G   GG  GG+S+   G G    A   N
Sbjct: 298 FGGGS----GSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRN 353

Query: 428 EFGETGLSGS 437
           + G  G S S
Sbjct: 354 QGGYGGSSSS 363



>gi|51873980|gb|AAH80591.1|   HNRPA3 protein [Homo sapiens]
          Length = 189

 Score = 38.9 bits (89), Expect = 0.061
 Identities = 49/197 (24%), Positives = 67/197 (34%), Gaps = 30/197 (15%)

Query: 161 RERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQT 220
           +E   AG+ R     +      G   G G G+   G        +G  G       G   
Sbjct: 16  QEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGREGYGGGG-------GGSR 68

Query: 221 SSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA 280
            S GG    D G   F  +    GGG   S    +  G  G+G N+ GG G  G      
Sbjct: 69  GSYGGG---DGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYG-NQGGGYGGGG------ 118

Query: 281 GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
           G+ G+    +          FG G   GG   N+ D G N SG   ++     G   G  
Sbjct: 119 GYDGYNEGGN----------FGGGNYGGGG--NYNDFG-NYSGQQQSNYGPMKGGSFGGR 165

Query: 341 SARNGFENSSGISEDSG 357
           S+ + +    G    SG
Sbjct: 166 SSGSPYGGGYGSGGGSG 182



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 39/159 (24%), Positives = 50/159 (31%), Gaps = 34/159 (21%)

Query: 284 GFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSAR 343
           G   +   ++ K  +   G    +GG   NF   G N  G  GN  +       G+   R
Sbjct: 4   GHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG------GNFGGR 57

Query: 344 NGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTW 403
            G+    G S  S    G  D         GGN                      GG  +
Sbjct: 58  EGYGGGGGGSRGS---YGGGDGGYNGFGGDGGNY--------------------GGGPGY 94

Query: 404 SSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           SS  G GGGG      G G  G    G  G  G  +G +
Sbjct: 95  SSRGGYGGGGP-----GYGNQGGGYGGGGGYDGYNEGGN 128



>gi|10434013|dbj|BAB14097.1|   unnamed protein product [Homo sapiens]
          Length = 523

 Score = 38.9 bits (89), Expect = 0.061
 Identities = 82/335 (24%), Positives = 119/335 (35%), Gaps = 62/335 (18%)

Query: 47  SLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKA 106
           SL    P  T   +      GS  +   PA    +S  +   S+ + P F++  G+  K+
Sbjct: 176 SLPTAVPTATSSSAADFSGFGSTLATSAPAT---SSQPTLTFSNTSTPTFNIPFGSSAKS 232

Query: 107 EDKS--GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGAT---GEDEDKSR 161
              S  G +       +E  PPG               KP  +  FG++   G     + 
Sbjct: 233 PLPSYPGANPQPTFGAAEGQPPGA-------------AKPALAPSFGSSFTFGNSAAPAA 279

Query: 162 ERWDAGNSRSEDSPA--------VGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT----- 208
               A  S  +  PA        +  G++    G     +AFG   S   +FG +     
Sbjct: 280 APTPAPPSMIKVVPAHVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFF 339

Query: 209 --GISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE 266
               SS      QT+SSG S S+  G T+    + F  GGS         +G   FGIN 
Sbjct: 340 GAATSSGFGATTQTASSGSSSSV-FGSTT---PSPFTFGGSAAP------AGSGSFGINV 389

Query: 267 IGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGA-------EFNFRDSGS 319
                  GS +    F  FG+  S S   S  F  GLG+   G         FN   +  
Sbjct: 390 ----ATPGSSTTTGAFS-FGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTE 444

Query: 320 NQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
           ++    G ++  F  N    GVG S +   F  SS
Sbjct: 445 SKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 479



>gi|47077184|dbj|BAD18513.1|   unnamed protein product [Homo sapiens]
          Length = 268

 Score = 38.9 bits (89), Expect = 0.061
 Identities = 36/144 (25%), Positives = 51/144 (35%), Gaps = 24/144 (16%)

Query: 322 SGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRS- 380
           SG  G       G G  ++ +    E++S   ED        ++ +   S  GG  + S 
Sbjct: 63  SGGGGGGGGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSA 122

Query: 381 ---------SDPDEAGNLSPGSDVSDSGGNTW-----------SSDSGSGGGGKSADELG 420
                    S  DE  +LSPG+  S SG                S  G GGG  S+  + 
Sbjct: 123 ESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGGGSSSSSVVS 182

Query: 421 VGAS---GLNEFGETGLSGSEKGS 441
            G     G    G +  SG  +GS
Sbjct: 183 SGGDEGYGTGGGGSSATSGGRRGS 206



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 43/206 (20%), Positives = 72/206 (34%), Gaps = 19/206 (9%)

Query: 27  GGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKS---EDTPAGGFFNSS 83
           GG   G   +  +    P  + + G   + E+   + +D  S      E++ A     SS
Sbjct: 70  GGGGVGGGEAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSS 129

Query: 84  SSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKK 143
             S  SD T+        +PG A   SGD     G +    P G    G    G S    
Sbjct: 130 GGSS-SDETRSL------SPGAASSSSGDGDGKEGLEEPKGPRGS--QGGGGGGSS---- 176

Query: 144 PLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSN 203
              S    ++G DE        +  +      ++   S G  L     + +    + D +
Sbjct: 177 ---SSSVVSSGGDEGYGTGGGGSSATSGGRRGSLEMSSDGEPLSRMDSEDSISSTIMDVD 233

Query: 204 SFGDTGISSKTVEGNQTSSSGGSVSI 229
           S   +G S+  +   Q S++  S +I
Sbjct: 234 STISSGRSTPAMMNGQGSTTSSSKNI 259



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 29/110 (26%), Positives = 37/110 (33%), Gaps = 10/110 (9%)

Query: 302 GLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILG 361
           G GE +  AE     SG + S +  + S     +  GD   + G E   G     G   G
Sbjct: 114 GGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSGDGDGKEGLEEPKGPRGSQGGGGG 173

Query: 362 SSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
            S    V           SS  DE      G   + SGG   S +  S G
Sbjct: 174 GSSSSSVV----------SSGGDEGYGTGGGGSSATSGGRRGSLEMSSDG 213



>gi|32879987|gb|AAP88824.1|   dishevelled, dsh homolog 2 (Drosophila) [Homo sapiens]
 gi|4758216|ref|NP_004413.1|   dishevelled 2 [Homo sapiens]
 gi|15928771|gb|AAH14844.1|   Dishevelled 2 [Homo sapiens]
 gi|2291008|gb|AAB65243.1|   dishevelled 2 [Homo sapiens]
 gi|6919871|sp|O14641|DVL2_HUMAN   Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2)
           (DSH homolog 2)
          Length = 736

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%)

Query: 32  GSSSSGDLDRKKPL-----------FSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFF 80
           GSS + D D   PL           FS ++ +P     +     +  S     T  GG  
Sbjct: 526 GSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSY----TYGGGSA 581

Query: 81  NSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFF-YGSSSSGDS 139
           +S  S G           G G  G+ E+++ +S+   GS+SE +  GG    G  +SG S
Sbjct: 582 SSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESEPSSRGGSLRRGGEASGTS 641

Query: 140 DKKKP 144
           D   P
Sbjct: 642 DGGPP 646



>gi|88041|pir||A31994   keratin 10, type I, epidermal - human
 gi|623409|gb|AAA60544.1|   keratin 10
          Length = 561

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 12/119 (10%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G GSSG   G G+G  +FG      +S G +        G+ +   GGS S   G  SF 
Sbjct: 448 GEGSSG---GGGRGGGSFGGGYGGGSSGGGSS-GGGYGGGSSSGGHGGSSSGGYGGGSFG 503

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
                 GGGS    S    S   G+G    GG+   G     +   G  S SS SV +S
Sbjct: 504 GGGGGYGGGS----SGGGSSSGGGYG----GGSSSGGGYGGGSSSGGHKSSSSGSVGES 554



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 42/155 (27%), Positives = 51/155 (32%), Gaps = 27/155 (17%)

Query: 211 SSKTVEGNQTSSSGGSVSIDLGDTSFR---SENQFVGGGSLNSISNLWDSGQEGFGINEI 267
           SSK    +++   GG      G +S R   S+    GG S    S         F     
Sbjct: 8   SSKQFSSSRSGGGGG------GGSSLRISSSKGSLGGGFSSGGFSG------GSFSRGSS 55

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN 327
           GG    GS     G  GFG  S      S  F    G + GG  F          G  G 
Sbjct: 56  GGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFG--------GGSFGG 107

Query: 328 SSKDFDGNGVGDSSARNGFENSSGISEDSGVILGS 362
            S  F G G G      GF    G   D G++ G+
Sbjct: 108 GS--FGGGGFGGGGFGGGF--GGGFGGDGGLLSGN 138



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 4/122 (3%)

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSS 290
           L D   R EN+     SL  +     SG  G G    GG    GS    +   G+G  SS
Sbjct: 428 LTDIKIRLENEIQTYRSL--LEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSS 485

Query: 291 SSVEK-SWLFEFGLGETKGGAE-FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFEN 348
           S     S    +G G   GG   +    SG   S   G       G G G  S+  G ++
Sbjct: 486 SGGHGGSSSGGYGGGSFGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGGYGGGSSSGGHKS 545

Query: 349 SS 350
           SS
Sbjct: 546 SS 547



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 9/96 (9%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFF---SLGLGAPGKAEDKSGDSQDAGGSKSED 123
           G      +  GG+   SSS G    +   +   S G G  G     SG    +GG     
Sbjct: 468 GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSFGGGGGGYGGGSSGGGSSSGGGYGGG 527

Query: 124 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDK 159
           +  GG + G SSSG         S   G+ GE   K
Sbjct: 528 SSSGGGYGGGSSSGGHK------SSSSGSVGESSSK 557



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 34/119 (28%), Positives = 37/119 (31%), Gaps = 8/119 (6%)

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
           G   SG  G     F G   G SS         G    SG   GSS          GG  
Sbjct: 448 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSS------GGYGGGS 501

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
                    G  S G   S  G    SS  G  GGG S+   G  +S     GE+   G
Sbjct: 502 FGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGGYGGGSSSG--GHKSSSSGSVGESSSKG 558



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 326 GNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDE 385
           G  S    G G G      G  +S G S   G   GSS         +GG+   SS    
Sbjct: 448 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSS---------SGGHGGSSSGGYG 498

Query: 386 AGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGS 437
            G+   G      G +   S SG G GG S+   G G    +   ++  SGS
Sbjct: 499 GGSFGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGGYGGGSSSGGHKSSSSGS 550



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 13/117 (11%)

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G+    GG +   +  GG+  GSS  G S        +  G++      S      G S 
Sbjct: 448 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGG-----GYGGGSSSGGHGGSSSGGYGGGSF 502

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSV 227
                  G GSSG   G       +G   S    +G  G SS    G   SSS GSV
Sbjct: 503 GGGGGGYGGGSSG---GGSSSGGGYGGGSSSGGGYGG-GSSS----GGHKSSSSGSV 551



>gi|56788377|ref|NP_001008564.1|   nucleoporin like 1 isoform b [Homo sapiens]
          Length = 587

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 51/222 (22%), Positives = 75/222 (33%), Gaps = 20/222 (9%)

Query: 78  GFFNSSSSSGDSDRTKPFFSLGLGAPGKAED--KSGDSQDAGGSKSEDTPPGGFFYGSSS 135
           G   S++ +     T   FS G GA          G+        +   P  GF  G   
Sbjct: 10  GTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPSSGFGTGLFG 69

Query: 136 SGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAF 195
           S      KP   F  G T      +      G S   + PA       L + +       
Sbjct: 70  S------KPATGFTLGGTNTGTPATTSAATTGFSLGFNKPAASATPFALPITSTSASGLT 123

Query: 196 GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVG-GGSLNSISNL 254
                 S     TG +   + G   +++  S  + LG           G GGSL   +N 
Sbjct: 124 LSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLG-------GALAGLGGSLFQSTN- 175

Query: 255 WDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS-DSSSSVEK 295
             +G  G G N +G    + + ++ AG +G G  D SSS +K
Sbjct: 176 --TGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDK 215



>gi|32395928|gb|AAP41817.1|   MUC19 [Homo sapiens]
          Length = 701

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 89/378 (23%), Positives = 140/378 (37%), Gaps = 46/378 (12%)

Query: 68  SPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPG 127
           +P S  T A     +S  +G     +    LG  +   AE KSG +  A GSK   T   
Sbjct: 12  APGSFSTAATTSPGASGVTGTGPTAETTTFLGGSSTTGAEIKSGATTGAPGSK---TGTA 68

Query: 128 GFFYGSS-SSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKL 186
               G++ +SG S+ +   FS    A      K+     A  S+   S  V  GSSG   
Sbjct: 69  KVLSGTTVASGSSNSEATTFSGITEAV-TVPSKNGSMTTALGSQLSSSQTVIPGSSGT-- 125

Query: 187 GAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGG 246
                  A G  V+ +     TG S   V G++T ++G ++S  +   S  +E     G 
Sbjct: 126 -ISHTTVAPGSSVTGTT----TGASDDQVTGSKTGTTGVALSTTVAPGSSSTEATTSTGV 180

Query: 247 SLNSISNLWDSGQE-GFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGE 305
              ++      GQ+ G         G   ++ A   F+G G+  S             G 
Sbjct: 181 HRTTV-----VGQKTGATTRGSAKQGTRSTIEATTSFRGTGTTGSG---------MNTGT 226

Query: 306 TKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQ 365
           T   +      S  N    +G S +   G+ +G          ++GI   + V  GSS+ 
Sbjct: 227 TGVVSGNTISPSSFNTEATSGTSERPNPGSEIG----------TTGIVSGTTVAPGSSNT 276

Query: 366 HEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVG-AS 424
                   GG  +  S     G ++ G+ +     NT ++ S   G        GVG A+
Sbjct: 277 EATTSLGNGGTTEAGSKIVTTG-ITTGTTIVPGSFNTKATTSTDVGVA-----TGVGMAT 330

Query: 425 GLNEF--GETGLSGSEKG 440
           G+     G +  +GS+ G
Sbjct: 331 GITNIISGRSQPTGSKTG 348



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 82/407 (20%), Positives = 141/407 (34%), Gaps = 48/407 (11%)

Query: 51  GSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKS 110
           G    T  + +     G+P S+   A     ++ +SG S+     FS G+        K+
Sbjct: 43  GGSSTTGAEIKSGATTGAPGSKTGTAKVLSGTTVASGSSNSEATTFS-GITEAVTVPSKN 101

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G    A GS+   +       GSS +       P  S     TG  +D+       G+  
Sbjct: 102 GSMTTALGSQLSSSQT--VIPGSSGTISHTTVAPGSSVTGTTTGASDDQV-----TGSK- 153

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSID 230
                   TG++G+ L       +   E + S     TG+   TV G +T ++    +  
Sbjct: 154 --------TGTTGVALSTTVAPGSSSTEATTS-----TGVHRTTVVGQKTGATTRGSAKQ 200

Query: 231 LGDTSFRSENQFVGGGSLNSISNLWDSG--------QEGFGINEIGGNGMSGSVSAEAGF 282
              ++  +   F G G+  S  N   +G           F      G     +  +E G 
Sbjct: 201 GTRSTIEATTSFRGTGTTGSGMNTGTTGVVSGNTISPSSFNTEATSGTSERPNPGSEIGT 260

Query: 283 KGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSA 342
            G  S ++ +           G +   A  +  + G+ ++G    ++    G   G +  
Sbjct: 261 TGIVSGTTVAP----------GSSNTEATTSLGNGGTTEAGSKIVTT----GITTGTTIV 306

Query: 343 RNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSD-SGGN 401
              F   +  S D GV  G      +    +G ++   S   + G    GS  +   GG 
Sbjct: 307 PGSFNTKATTSTDVGVATGVGMATGITNIISGRSQPTGS---KTGYTVTGSGTTALPGGF 363

Query: 402 TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEATP 448
              +  GS G   S +   V +SG+    ET +SG  K +    + P
Sbjct: 364 RTGNTPGSTGVTSSQEGTTVVSSGITGIPETSISGPSKEASDKTSAP 410



>gi|244507|gb|AAB21313.1|   keratin 10 V2 subdomain 117 amino acid variant [human, Peptide
           Partial, 117 aa]
          Length = 117

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 12/119 (10%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G GSSG   G G+G  +FG      +S G +        G+ +   GGS S   G  SF 
Sbjct: 4   GEGSSG---GGGRGGGSFGGGYGGGSSGGGSS-GGGYGGGSSSGGHGGSSSGGYGGGSFG 59

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKS 296
                 GGGS    S    S   G+G    GG+   G     +   G  S SS SV +S
Sbjct: 60  GGGGGYGGGS----SGGGSSSGGGYG----GGSSSGGGYGGGSSSGGHKSSSSGSVGES 110



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 9/96 (9%)

Query: 67  GSPKSEDTPAGGFFNSSSSSGDSDRTKPFF---SLGLGAPGKAEDKSGDSQDAGGSKSED 123
           G      +  GG+   SSS G    +   +   S G G  G     SG    +GG     
Sbjct: 24  GGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSFGGGGGGYGGGSSGGGSSSGGGYGGG 83

Query: 124 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDK 159
           +  GG + G SSSG         S   G+ GE   K
Sbjct: 84  SSSGGGYGGGSSSGGHK------SSSSGSVGESSSK 113



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 34/119 (28%), Positives = 37/119 (31%), Gaps = 8/119 (6%)

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
           G   SG  G     F G   G SS         G    SG   GSS          GG  
Sbjct: 4   GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSS------GGYGGGS 57

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSG 436
                    G  S G   S  G    SS  G  GGG S+   G  +S     GE+   G
Sbjct: 58  FGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGGYGGGSSSG--GHKSSSSGSVGESSSKG 114



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 326 GNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDE 385
           G  S    G G G      G  +S G S   G   GSS         +GG+   SS    
Sbjct: 4   GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSS---------SGGHGGSSSGGYG 54

Query: 386 AGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGS 437
            G+   G      G +   S SG G GG S+   G G    +   ++  SGS
Sbjct: 55  GGSFGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGGYGGGSSSGGHKSSSSGS 106



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 2/96 (2%)

Query: 257 SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEK-SWLFEFGLGETKGGAE-FNF 314
           SG  G G    GG    GS    +   G+G  SSS     S    +G G   GG   +  
Sbjct: 8   SGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSFGGGGGGYGG 67

Query: 315 RDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSS 350
             SG   S   G       G G G  S+  G ++SS
Sbjct: 68  GSSGGGSSSGGGYGGGSSSGGGYGGGSSSGGHKSSS 103



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 13/117 (11%)

Query: 111 GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSR 170
           G+    GG +   +  GG+  GSS  G S        +  G++      S      G S 
Sbjct: 4   GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGG-----GYGGGSSSGGHGGSSSGGYGGGSF 58

Query: 171 SEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSV 227
                  G GSSG   G       +G   S    +G  G SS    G   SSS GSV
Sbjct: 59  GGGGGGYGGGSSG---GGSSSGGGYGGGSSSGGGYGG-GSSS----GGHKSSSSGSV 107



>gi|133254|sp|P09651|ROA1_HUMAN   Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
           protein) (Single-strand binding protein) (hnRNP core
           protein A1)
          Length = 372

 Score = 38.5 bits (88), Expect = 0.080
 Identities = 50/190 (26%), Positives = 69/190 (36%), Gaps = 32/190 (16%)

Query: 257 SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRD 316
           SG   FG    GG G + +      F G G               G G ++GG  +    
Sbjct: 197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRG---------------GFGGSRGGGGYGGSG 241

Query: 317 SGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
            G N  G++G     + G G G S    G+ +      + G   G S  ++   +  GG 
Sbjct: 242 DGYNGFGNDGG----YGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYD-SYNNGGG- 295

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGG-NTWSSDSG--SGG--GGKSADELGVG----ASGLN 427
             R        N   G   +D G  N  SS+ G   GG  GG+S+   G G    A   N
Sbjct: 296 --RGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRN 353

Query: 428 EFGETGLSGS 437
           + G  G S S
Sbjct: 354 QGGYGGSSSS 363



>gi|40354192|ref|NP_000412.2|   keratin 10 [Homo sapiens]
 gi|21961605|gb|AAH34697.1|   Keratin 10 [Homo sapiens]
          Length = 584

 Score = 38.1 bits (87), Expect = 0.10
 Identities = 36/133 (27%), Positives = 46/133 (34%), Gaps = 12/133 (9%)

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSS 363
           G  +GG  F     G +  G  G+S   + G   G S    G  +S G S   G   GSS
Sbjct: 461 GGGRGGGSFGGGYGGGSSGG--GSSGGGYGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS 518

Query: 364 DQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGA 423
                      G    SS     G  S G      GG++    S  GG G  +   G  +
Sbjct: 519 S----------GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKS 568

Query: 424 SGLNEFGETGLSG 436
           S     GE+   G
Sbjct: 569 SSSGSVGESSSKG 581



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 46/152 (30%), Positives = 57/152 (37%), Gaps = 28/152 (18%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G GSSG   G G+G  +FG      +S G  G S     G    SSGG      G +   
Sbjct: 455 GEGSSG---GGGRGGGSFGGGYGGGSSGG--GSSGGGYGGGHGGSSGGGYGG--GSSGGG 507

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSW 297
           S     GGGS +           G G +  GG G   S     G+ G  S   SS     
Sbjct: 508 SSGGGYGGGSSSG----------GHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG- 556

Query: 298 LFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
              +G G + GG +       S+ SG  G SS
Sbjct: 557 ---YGGGSSSGGHK-------SSSSGSVGESS 578



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 35/132 (26%), Positives = 45/132 (34%), Gaps = 14/132 (10%)

Query: 19  GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
           G+   S  GG+  GSS  G             G  G     S      G      +  GG
Sbjct: 463 GRGGGSFGGGYGGGSSGGGSSG----------GGYGGGHGGSSGGGYGGGSSGGGSSGGG 512

Query: 79  FFNSSSSSGDSDRTKPFF---SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSS 135
           +   SSS G    +   +   S G G  G     SG    +GG     +  GG    SS 
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572

Query: 136 S-GDSDKKKPLF 146
           S G+S  K P +
Sbjct: 573 SVGESSSKGPRY 584



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 36/131 (27%), Positives = 45/131 (34%), Gaps = 24/131 (18%)

Query: 244 GGGSLNSISNLWDSGQEGFGINEIGGNGMS------------GSVSAEAGFKGFGSDSSS 291
           GGG ++S+      G  G G +  G +G S            GS     G  GFG  S  
Sbjct: 27  GGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFR 86

Query: 292 SVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
               S  F    G + GG  F          G  G  S  F G G G      GF    G
Sbjct: 87  GSYGSSSFGGSYGGSFGGGSFG--------GGSFGGGS--FGGGGFGGGGFGGGF--GGG 134

Query: 352 ISEDSGVILGS 362
              D G++ G+
Sbjct: 135 FGGDGGLLSGN 145



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 36/122 (29%), Positives = 45/122 (36%), Gaps = 7/122 (5%)

Query: 318 GSNQSGDNGNSS--KDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 375
           GS+  G  G  S    + G   G  S+  G+    G S   G   GSS       S  GG
Sbjct: 457 GSSGGGGRGGGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGGG----SSGGG 512

Query: 376 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLS 435
               SS     G+ S G     SGG       GS G G S+   G G    +   ++  S
Sbjct: 513 YGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSG-GGSSSGGGYGGGSSSGGHKSSSS 571

Query: 436 GS 437
           GS
Sbjct: 572 GS 573



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 35/132 (26%), Positives = 48/132 (36%), Gaps = 16/132 (12%)

Query: 260 EGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLF----------EFGLGETKGG 309
           EG G +  GG G  GS        G+G  SS        +           +G G + GG
Sbjct: 454 EGEGSSGGGGRG-GGSFGG-----GYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGGG 507

Query: 310 AEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVE 369
           +       GS+  G  G+SS  + G   G      G  +S G S   G   G S     +
Sbjct: 508 SSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHK 567

Query: 370 LSRTGGNRKRSS 381
            S +G   + SS
Sbjct: 568 SSSSGSVGESSS 579



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 7/76 (9%)

Query: 367 EVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGL 426
           E E S  GG R         G+   G     SGG +     G G GG S    G G+SG 
Sbjct: 454 EGEGSSGGGGRG-------GGSFGGGYGGGSSGGGSSGGGYGGGHGGSSGGGYGGGSSGG 506

Query: 427 NEFGETGLSGSEKGSH 442
              G     GS  G H
Sbjct: 507 GSSGGGYGGGSSSGGH 522



>gi|55962039|emb|CAI18323.1|   corneodesmosin [Homo sapiens]
          Length = 529

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 49/162 (30%), Positives = 60/162 (37%), Gaps = 15/162 (9%)

Query: 133 SSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGD 192
           SS SG S     + S      G     S      G S     P  GTG S +   +G G 
Sbjct: 66  SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP--GTGYSQVSYSSGSGS 123

Query: 193 AAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR-SENQF-VGGGSLNS 250
           +  G   S S+  G    SS +  GN  S SG S S     +SF+ S + F VG GS   
Sbjct: 124 SLQG--ASGSSQLG----SSSSHSGNSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA-- 175

Query: 251 ISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSS 292
              L  +     GI      G S S S   G    G   SS+
Sbjct: 176 ---LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSN 214



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 36/136 (26%)

Query: 320 NQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKR 379
           + SG +  S     G+ +  SSAR+    SSG S  S +  G S                
Sbjct: 61  DSSGFSSYSGSSSSGSSI--SSARSSGGGSSGSSSGSSIAQGGS---------------- 102

Query: 380 SSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEK 439
                 AG+  PG+         +S  S S G G S      GASG ++ G +       
Sbjct: 103 ------AGSFKPGTG--------YSQVSYSSGSGSSLQ----GASGSSQLGSSSSHSGNS 144

Query: 440 GSHIPEATPKYSETNA 455
           GSH   ++   S +++
Sbjct: 145 GSHSGSSSSHSSSSSS 160



>gi|55956910|ref|NP_002421.3|   meningioma  1 [Homo sapiens]
 gi|57209160|emb|CAI17971.2|   OTTHUMP00000028743 [Homo sapiens]
 gi|57208273|emb|CAI20309.2|   OTTHUMP00000028743 [Homo sapiens]
          Length = 1320

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 84/339 (24%), Positives = 115/339 (33%), Gaps = 63/339 (18%)

Query: 96  FSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGE 155
           F   LG  G+ +   G       + SE  PP   F  S+  G          F FGA G 
Sbjct: 702 FGGSLGGLGQLQSP-GAGVGLPSAASERRPPPPDFATSALGGQP-------GFPFGAAGR 753

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
                          S  S   G GSSG   G G       F+ S   S    G  S   
Sbjct: 754 QSTPH----SGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGS 809

Query: 216 EGNQTSSSG--GSVSIDLGDTSFRSENQFVGGGSLNSISNLWD--SGQEGFGINEIGGNG 271
               +S     G   +    T+ ++    +G  +LN   N  +   G+     NE  G  
Sbjct: 810 FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAA 869

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           ++G+          GSD            +  G T  GA      SG++ SG   +   +
Sbjct: 870 VAGNP---------GSD------------YFPGGTAPGAPGPGGPSGTSSSGSKASGPPN 908

Query: 332 FDGNGVGDSSARN-GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G G S + N   E++SG   D   + G            GG R R     ++G++S
Sbjct: 909 PPAQGDGTSLSPNYTLESTSG--NDGKPVSG------------GGGRGRGRRKRDSGHVS 954

Query: 391 PG------SDVSDSGGNTWSSD-----SGSGGGGKSADE 418
           PG      S   DSGG    S      SG+  GG SA E
Sbjct: 955 PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGE 993



>gi|7705545|ref|NP_056932.1|   cytokeratin 2 [Homo sapiens]
 gi|2119218|pir||I53169   cytokeratin 2 - human
 gi|547752|sp|Q01546|K22O_HUMAN   Keratin, type II cytoskeletal 2 oral (Cytokeratin 2P) (K2P) (CK 2P)
 gi|181390|gb|AAA35746.1|   cytokeratin 2
          Length = 638

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 18/131 (13%)

Query: 202 SNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEG 261
           +++ G +G S     G   S SGG      G +S  S    V GGS         SG  G
Sbjct: 513 TSTSGSSGSSRGVFGGVSGSGSGGYKG---GSSSSSSSGYGVSGGS--------GSGYGG 561

Query: 262 FGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQ 321
                 GG G SGS  + +     G   S SV  S     G+G + G  + +       +
Sbjct: 562 VSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHS-----GMGSSSGSIQTS--GGSGYK 614

Query: 322 SGDNGNSSKDF 332
           SG  G++S  F
Sbjct: 615 SGGGGSTSIRF 625



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDG-NGVGDSSARNGFENSS----GISEDSGV 358
           GE +     +   + ++ SG +G+S   F G +G G    + G  +SS    G+S  SG 
Sbjct: 498 GECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGS 557

Query: 359 ILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG-GNTWSSDSGSGGGGKSAD 417
             G           + G+ + SS     G     S VS SG G++  S   SGG G  + 
Sbjct: 558 GYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSIS-VSHSGMGSSSGSIQTSGGSGYKS- 615

Query: 418 ELGVGASGLNEFGETGLSGSEKGS 441
             G G S    F +T  S     +
Sbjct: 616 --GGGGSTSIRFSQTTSSSQHSST 637



>gi|4501991|ref|NP_001126.1|   aggrecan 1 isoform 1 precursor [Homo sapiens]
 gi|178259|gb|AAA62824.1|   large aggregating cartilage proteoglycan core protein
          Length = 2316

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 91/354 (25%), Positives = 120/354 (33%), Gaps = 51/354 (14%)

Query: 110  SGDSQDAGGSKSEDTP--PGGFFYGSSSSGDSDKKKPLFS---FEFGATGEDEDKSRERW 164
            SG+  +   S  ED    P G    +S+SG  D  +        E  A+G  +       
Sbjct: 1377 SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGVP-- 1434

Query: 165  DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
              G      +  VGT  SGL  G        G E S S +   +G+ S    G +     
Sbjct: 1435 SGGEGLETSASEVGTDLSGLPSGRE------GLETSASGAEDLSGLPS----GKEDLVGS 1484

Query: 225  GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
             S  +DLG    +  +  +G G     S L      GF     G +  SG  S    F G
Sbjct: 1485 ASGDLDLG----KLPSGTLGSGQAPETSGL----PSGFSGEYSGVDLGSGPPSGLPDFSG 1536

Query: 285  FGSDSSS-SVEKSWLFEFGLGETKGGAEFN--FRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
              S   + S+  S L E     T    E       SG+ +     +S  D  G   G  S
Sbjct: 1537 LPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPS 1596

Query: 342  ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
                   +SG  + SG I G            G + + S  PD +G  S         G 
Sbjct: 1597 GTELSGQASGSPDVSGEIPGLF----------GVSGQPSGFPDTSGETS---------GV 1637

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG----SHIPEATPKYS 451
            T  S   SG  G S +  GV       FG T LSG   G    S  P   P +S
Sbjct: 1638 TELSGLSSGQPGVSGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1691



>gi|6995994|ref|NP_037359.1|   aggrecan 1 isoform 2 precursor [Homo sapiens]
          Length = 2415

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 91/354 (25%), Positives = 120/354 (33%), Gaps = 51/354 (14%)

Query: 110  SGDSQDAGGSKSEDTP--PGGFFYGSSSSGDSDKKKPLFS---FEFGATGEDEDKSRERW 164
            SG+  +   S  ED    P G    +S+SG  D  +        E  A+G  +       
Sbjct: 1377 SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGVP-- 1434

Query: 165  DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
              G      +  VGT  SGL  G        G E S S +   +G+ S    G +     
Sbjct: 1435 SGGEGLETSASEVGTDLSGLPSGRE------GLETSASGAEDLSGLPS----GKEDLVGS 1484

Query: 225  GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
             S  +DLG    +  +  +G G     S L      GF     G +  SG  S    F G
Sbjct: 1485 ASGDLDLG----KLPSGTLGSGQAPETSGL----PSGFSGEYSGVDLGSGPPSGLPDFSG 1536

Query: 285  FGSDSSS-SVEKSWLFEFGLGETKGGAEFN--FRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
              S   + S+  S L E     T    E       SG+ +     +S  D  G   G  S
Sbjct: 1537 LPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPS 1596

Query: 342  ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
                   +SG  + SG I G            G + + S  PD +G  S         G 
Sbjct: 1597 GTELSGQASGSPDVSGEIPGLF----------GVSGQPSGFPDTSGETS---------GV 1637

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG----SHIPEATPKYS 451
            T  S   SG  G S +  GV       FG T LSG   G    S  P   P +S
Sbjct: 1638 TELSGLSSGQPGVSGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1691



>gi|55733689|emb|CAA57693.2|   MN1 protein [Homo sapiens]
          Length = 1319

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 84/339 (24%), Positives = 115/339 (33%), Gaps = 63/339 (18%)

Query: 96  FSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGE 155
           F   LG  G+ +   G       + SE  PP   F  S+  G          F FGA G 
Sbjct: 701 FGGSLGGLGQLQSP-GAGVGLPSAASERRPPPPDFATSALGGQP-------GFPFGAAGR 752

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
                          S  S   G GSSG   G G       F+ S   S    G  S   
Sbjct: 753 QSTPH----SGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGS 808

Query: 216 EGNQTSSSG--GSVSIDLGDTSFRSENQFVGGGSLNSISNLWD--SGQEGFGINEIGGNG 271
               +S     G   +    T+ ++    +G  +LN   N  +   G+     NE  G  
Sbjct: 809 FNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAA 868

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           ++G+          GSD            +  G T  GA      SG++ SG   +   +
Sbjct: 869 VAGNP---------GSD------------YFPGGTAPGAPGPGGPSGTSSSGSKASGPPN 907

Query: 332 FDGNGVGDSSARN-GFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G G S + N   E++SG   D   + G            GG R R     ++G++S
Sbjct: 908 PPAQGDGTSLSPNYTLESTSG--NDGKPVSG------------GGGRGRGRRKRDSGHVS 953

Query: 391 PG------SDVSDSGGNTWSSD-----SGSGGGGKSADE 418
           PG      S   DSGG    S      SG+  GG SA E
Sbjct: 954 PGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGE 992



>gi|31074629|emb|CAD91891.1|   keratin 2p [Homo sapiens]
          Length = 638

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 18/131 (13%)

Query: 202 SNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEG 261
           +++ G +G S     G   S SGG      G +S  S    V GGS         SG  G
Sbjct: 513 TSTSGSSGSSRGVFGGVSGSGSGGYKG---GSSSSSSSGYGVSGGS--------GSGYGG 561

Query: 262 FGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQ 321
                 GG G SGS  + +     G   S SV  S     G+G + G  + +       +
Sbjct: 562 VSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHS-----GMGSSSGSIQTS--GGSGYK 614

Query: 322 SGDNGNSSKDF 332
           SG  G++S  F
Sbjct: 615 SGGGGSTSIRF 625



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 39/144 (27%), Positives = 58/144 (40%), Gaps = 10/144 (6%)

Query: 304 GETKGGAEFNFRDSGSNQSGDNGNSSKDFDG-NGVGDSSARNGFENSS----GISEDSGV 358
           GE +     +   + ++ SG +G+S   F G +G G    + G  +SS    G+S  SG 
Sbjct: 498 GECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGS 557

Query: 359 ILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSG-GNTWSSDSGSGGGGKSAD 417
             G           + G+ + SS     G     S VS SG G++  S   SGG G  + 
Sbjct: 558 GYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSIS-VSHSGMGSSSGSIQTSGGSGYKS- 615

Query: 418 ELGVGASGLNEFGETGLSGSEKGS 441
             G G S    F +T  S     +
Sbjct: 616 --GGGGSTSIRFSQTTSSSQHSST 637



>gi|25756916|pir||A39086   aggrecan precursor, cartilage long splice form [validated] - human
          Length = 2415

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 91/354 (25%), Positives = 120/354 (33%), Gaps = 51/354 (14%)

Query: 110  SGDSQDAGGSKSEDTP--PGGFFYGSSSSGDSDKKKPLFS---FEFGATGEDEDKSRERW 164
            SG+  +   S  ED    P G    +S+SG  D  +        E  A+G  +       
Sbjct: 1377 SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGVP-- 1434

Query: 165  DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
              G      +  VGT  SGL  G        G E S S +   +G+ S    G +     
Sbjct: 1435 SGGEGLETSASEVGTDLSGLPSGRE------GLETSASGAEDLSGLPS----GKEDLVGS 1484

Query: 225  GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
             S  +DLG    +  +  +G G     S L      GF     G +  SG  S    F G
Sbjct: 1485 ASGDLDLG----KLPSGTLGSGQAPETSGL----PSGFSGEYSGVDLGSGPPSGLPDFSG 1536

Query: 285  FGSDSSS-SVEKSWLFEFGLGETKGGAEFN--FRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
              S   + S+  S L E     T    E       SG+ +     +S  D  G   G  S
Sbjct: 1537 LPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPS 1596

Query: 342  ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
                   +SG  + SG I G            G + + S  PD +G  S         G 
Sbjct: 1597 GTELSGQASGSPDVSGEIPGLF----------GVSGQPSGFPDTSGETS---------GV 1637

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG----SHIPEATPKYS 451
            T  S   SG  G S +  GV       FG T LSG   G    S  P   P +S
Sbjct: 1638 TELSGLSSGQPGVSGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1691



>gi|11360063|pir||T46488   hypothetical protein DKFZp434J065.1 - human (fragment)
          Length = 741

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 85/425 (20%), Positives = 155/425 (36%), Gaps = 94/425 (22%)

Query: 477 AVGKSYEVCEDGIQH-----CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTC 531
           A+G++       ++H     C  I G+Y  +C +   L++D     I + C   D    C
Sbjct: 18  ALGEAKRPTRKTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--C 75

Query: 532 DTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQ 589
           +      +LC +  PG+F         VC   +C   +   E G    A   C++     
Sbjct: 76  E------QLCVNV-PGSF---------VC---QCYSGYALAEDGKRCVAVDYCASENHGC 116

Query: 590 DSECVSGCTCPEDKIQIFNASSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-V 647
           + ECV             NA  SYL Q    F                ++ P++ T T +
Sbjct: 117 EHECV-------------NADGSYLCQCHEGF----------------ALNPDEKTCTKI 147

Query: 648 GLCGSYNNKAEDDFMSSQNILE-KTSQAFANSWEMMSCPK---------GNPSSCISIEK 697
             C S N+  + + +++ +       + F  + +  +C +         G    C+++E+
Sbjct: 148 DYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEE 207

Query: 698 EKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVK 754
             +   H G  LD +G   +C  + +       C++     E+S  C C+   ++   +K
Sbjct: 208 SYYCRCHRGYTLDPNG--KTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLK 265

Query: 755 ACAEKETYIVGWRTGLCEHS-----------CPSGLVFKYNVKACNSSCRSLSERDRSCD 803
            C+  +  ++      CE+S           CP G V + + K C +   S +  D  C+
Sbjct: 266 TCSRVDYCLLSDHG--CEYSCVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCE 322

Query: 804 VEDVPVDG---CTCPDAMYQNNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
              V  +    C C +      +G  C  K  C     D   +   +   D   C C +G
Sbjct: 323 HSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEG 380

Query: 860 ILLCQ 864
             L +
Sbjct: 381 FRLAE 385



>gi|58218973|ref|NP_001010850.1|   fusion (involved in t(12;16) in malignant liposarcoma) isoform b
           [Homo sapiens]
          Length = 263

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 52/222 (23%), Positives = 83/222 (37%), Gaps = 22/222 (9%)

Query: 196 GFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLG---DTSFRSENQFVGGGSLNSIS 252
           G+    S  +G    S  + +   TS  G S     G   +T + +++   G GS     
Sbjct: 24  GYSQQSSQPYGQQSYSGYS-QSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYG 82

Query: 253 NLWDSGQEGFGI-NEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAE 311
           +   S Q  +G  +   G G   + S+ +G  G  S SSS            G+ + G+ 
Sbjct: 83  SS-QSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSS-----------YGQPQSGS- 129

Query: 312 FNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELS 371
           ++ + S   Q    G         G G    +N + +SSG     G   G+  Q +  +S
Sbjct: 130 YSQQPSYGGQQQSYGQQQSYNPPQGYGQ---QNQYNSSSGGGGGGGGG-GNYGQDQSSMS 185

Query: 372 RTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGG 413
             GG+     + D++G    G       G      SG GGGG
Sbjct: 186 SGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGG 227



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 64/288 (22%), Positives = 95/288 (32%), Gaps = 59/288 (20%)

Query: 74  TPAGGFFNSSSSSGDSDRT-KPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYG 132
           T + G + +    G S ++ +P+         ++ D SG  Q +  S  +    G   YG
Sbjct: 11  TQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTG---YG 67

Query: 133 SSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGD 192
           + S+             +G+TG            G+S+S  S            G     
Sbjct: 68  TQSTPQG----------YGSTG----------GYGSSQSSQS----------SYGQQSSY 97

Query: 193 AAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSIS 252
             +G + + S++ G  G SS++    Q  S   S     G        Q    G   S +
Sbjct: 98  PGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYG-------GQQQSYGQQQSYN 150

Query: 253 NLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEF 312
                GQ+    +  GG G  G      G   +G D SS            G   GG   
Sbjct: 151 PPQGYGQQNQYNSSSGGGGGGG------GGGNYGQDQSS---------MSSGGGSGGGYG 195

Query: 313 NFRDSGSNQSGDNGNSSKDF---DGNGVGDSSARNGFENSSGISEDSG 357
           N   SG   SG  G   +      G+G G      G+  SSG  E  G
Sbjct: 196 NQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRG 243



>gi|129886|sp|P16112|PGCA_HUMAN   Aggrecan core protein precursor (Cartilage-specific proteoglycan core
            protein) (CSPCP) (Chondroitin sulfate proteoglycan core
            protein 1)
          Length = 2415

 Score = 37.7 bits (86), Expect = 0.14
 Identities = 91/354 (25%), Positives = 120/354 (33%), Gaps = 51/354 (14%)

Query: 110  SGDSQDAGGSKSEDTP--PGGFFYGSSSSGDSDKKKPLFS---FEFGATGEDEDKSRERW 164
            SG+  +   S  ED    P G    +S+SG  D  +        E  A+G  +       
Sbjct: 1377 SGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGVP-- 1434

Query: 165  DAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSG 224
              G      +  VGT  SGL  G        G E S S +   +G+ S    G +     
Sbjct: 1435 SGGEGLETSASEVGTDLSGLPSGRE------GLETSASGAEDLSGLPS----GKEDLVGS 1484

Query: 225  GSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG 284
             S  +DLG    +  +  +G G     S L      GF     G +  SG  S    F G
Sbjct: 1485 ASGDLDLG----KLPSGTLGSGQAPETSGL----PSGFSGEYSGVDLGSGPPSGLPDFSG 1536

Query: 285  FGSDSSS-SVEKSWLFEFGLGETKGGAEFN--FRDSGSNQSGDNGNSSKDFDGNGVGDSS 341
              S   + S+  S L E     T    E       SG+ +     +S  D  G   G  S
Sbjct: 1537 LPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPS 1596

Query: 342  ARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGN 401
                   +SG  + SG I G            G + + S  PD +G  S         G 
Sbjct: 1597 GTELSGQASGSPDVSGEIPGLF----------GVSGQPSGFPDTSGETS---------GV 1637

Query: 402  TWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKG----SHIPEATPKYS 451
            T  S   SG  G S +  GV       FG T LSG   G    S  P   P +S
Sbjct: 1638 TELSGLSSGQPGVSGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFS 1691



>gi|7428712|pir||KRHU2   keratin 1, type II, cytoskeletal - human
          Length = 643

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 46/181 (25%), Positives = 63/181 (34%), Gaps = 33/181 (18%)

Query: 196 GFEVSDSNSFGDTGISS--KTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISN 253
           G+      SFG  GI +  +    + T  SGG      G   F S     GGGS  +   
Sbjct: 9   GYRSGGGFSFGFAGIINYQRRTTSSSTRRSGG------GGGRFSSSGG--GGGSFGAGG- 59

Query: 254 LWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFN 313
                  GFG   + G+G  GS+++ +G +G G  S            G G   GG  F 
Sbjct: 60  -------GFGSRSLAGSG--GSIASISGARGGGGGS------------GFGGGYGGGGFG 98

Query: 314 FRDSGSNQSGDNGNSSKDFDGNGVGDSS-ARNGFENSSGISEDSGVILGSSDQHEVELSR 372
               G    G  G     F G G G       GF    G     G +       EV +++
Sbjct: 99  GGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGGYGGGYGPVCSPGGIQEVTINQ 158

Query: 373 T 373
           +
Sbjct: 159 S 159



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 34/123 (27%), Positives = 43/123 (34%), Gaps = 11/123 (8%)

Query: 304 GETKGGAEFNFRDSGSNQ-SGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGS 362
           G ++GG    +   GS+  SG     S    G G G   +  G   S G S  SG   G 
Sbjct: 514 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGGSYGSGGSSYGSG---GG 570

Query: 363 SDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVG 422
              H       G     SS     G    G   S  G  +    SG   GG+ +   GV 
Sbjct: 571 GGGH-------GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSSGGRGSSSGGVK 623

Query: 423 ASG 425
           +SG
Sbjct: 624 SSG 626



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 38/149 (25%), Positives = 55/149 (36%), Gaps = 14/149 (9%)

Query: 215 VEGNQTSSSGG-----SVSIDLGDTSFRSE-NQFVGGGSLNSISNLWDSGQEGFGINEIG 268
           +EG ++  SG      SV++    TS     ++  GGG   S  + + SG   +G    G
Sbjct: 485 LEGEESRMSGECAPNVSVTVSTSHTSISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGG 544

Query: 269 GNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN- 327
           G G     S    +   GS   S         +G G + GG        G   SG  G+ 
Sbjct: 545 GGGRGSYGSGGGSYGSGGSSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 604

Query: 328 ---SSKDFDGNGVGDSSARNGFENSSGIS 353
              S     G G    S+  G ++S G S
Sbjct: 605 GGSSGGSSGGRG----SSSGGVKSSGGSS 629



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 45/156 (28%), Positives = 50/156 (32%), Gaps = 33/156 (21%)

Query: 135 SSGDSDKKKPLFSFEFGAT----GEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
           SSG   +    FSF F             S  R   G  R   S     G  G   GAG 
Sbjct: 5   SSGSGYRSGGGFSFGFAGIINYQRRTTSSSTRRSGGGGGRFSSS-----GGGGGSFGAGG 59

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNS 250
           G   FG     S S   +G S  ++ G +    G       G   F       GGG    
Sbjct: 60  G---FG-----SRSLAGSGGSIASISGARGGGGGSGFGGGYGGGGF-------GGGGF-- 102

Query: 251 ISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG 286
                  G  GFG   IGG G  G  S   GF G G
Sbjct: 103 -------GGGGFGGGGIGGGGFGGFGSGGGGFGGGG 131



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 40/157 (25%), Positives = 55/157 (35%), Gaps = 19/157 (12%)

Query: 166 AGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG 225
           +G      S  V T  + +  G  +G    G+  S  +S+G  G S     G+     GG
Sbjct: 493 SGECAPNVSVTVSTSHTSISGGGSRGGGGGGYG-SGGSSYGSGGGSY----GSGGGGGGG 547

Query: 226 SVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGF 285
             S   G  S+ S     G G        + SG    G     G G  GS    +G +G 
Sbjct: 548 RGSYGSGGGSYGSGGSSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGS----SGGRGS 603

Query: 286 GSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS 322
           G  SS           G G + GG     + SG + S
Sbjct: 604 GGGSSGGSSG------GRGSSSGGV----KSSGGSSS 630



>gi|4507353|ref|NP_003478.1|   TBP-associated factor 15 isoform 2 [Homo sapiens]
 gi|3763907|dbj|BAA33812.1|   RBP56/hTAFII68 [Homo sapiens]
 gi|27501920|gb|AAO13485.1|   TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated
           factor, 68kDa [Homo sapiens]
 gi|7440065|pir||S71954   RNA/ssDNA-binding protein TAFII68 - human
 gi|1628403|emb|CAA67398.1|   hTAFII68 [Homo sapiens]
          Length = 589

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 46/180 (25%), Positives = 59/180 (32%), Gaps = 26/180 (14%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD--N 325
           GG+        E G++G G                 G+  GG     R SG   SGD   
Sbjct: 388 GGDFRGRGYGGERGYRGRGGRGGDRGGYG-------GDRSGGGYGGDRSSGGGYSGDRSG 440

Query: 326 GNSSKDFDGNGV-GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPD 384
           G    D  G G  GD     G +   G   D G   G       +    GG+R      D
Sbjct: 441 GGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG------DRGGYGGDRGGGYGGD 494

Query: 385 EAGNLSPGSDVSDSGGNT--WSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
             G    G D    GG+   +  D G  GG +S      G  G +  G +G  G   G +
Sbjct: 495 RGGY---GGDRGGYGGDRGGYGGDRGGYGGDRSR-----GGYGGDRGGGSGYGGDRSGGY 546



>gi|14192943|ref|NP_115822.1|   MEGF10 protein [Homo sapiens]
 gi|14017777|dbj|BAB47409.1|   MEGF10 protein (KIAA1780) [Homo sapiens]
          Length = 1140

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 55/194 (28%), Positives = 72/194 (37%), Gaps = 47/194 (24%)

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPS 777
           C+   +P  Y E C++  C+C+N  DC          +   K T   G++   C   CP 
Sbjct: 396 CNETCSPGFYGEACQQI-CSCQNGADC---------DSVTGKCTCAPGFKGIDCSTPCPL 445

Query: 778 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCP------DAMYQNNEG----NC 826
           G    Y +  C+S C    + D  C     PVDG CTC       D   +   G     C
Sbjct: 446 G---TYGIN-CSSRCG--CKNDAVCS----PVDGSCTCKAGWHGVDCSIRCPSGTWGFGC 495

Query: 827 VLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGIL--LCQIPI-DLTL-QNCSGGAEYVD 882
            L  QC   +N      G   +  D  C C  G     C++P  D T   NC   AE  D
Sbjct: 496 NLTCQC---LN------GGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNC---AERCD 543

Query: 883 CSDPKAQRRTNRTC 896
           CS       T   C
Sbjct: 544 CSHADGCHPTTGHC 557



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 53/219 (24%), Positives = 73/219 (33%), Gaps = 34/219 (15%)

Query: 684 CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 743
           CP+G      S E     + H G   D++     C P    +   +EC   T     ++ 
Sbjct: 268 CPEGRFGKNCSQE----CQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAET 323

Query: 744 CLCTILGN--YVKACAEKETYIVGWRTGLCE-HSCPSGLVFKYNVKACNSSCRSLSERDR 800
           C C   G   +V      E    G R   CE   CP GL   Y +K C+  C    E   
Sbjct: 324 CQCVNGGKCYHVSGACLCEAGFAGER---CEARLCPEGL---YGIK-CDKRCPCHLENTH 376

Query: 801 SCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGI 860
           SC     P+ G              C  K        +E   PG         C C++G 
Sbjct: 377 SCH----PMSG-------------ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419

Query: 861 LLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTR 899
               +    T   C+ G + +DCS P         CS+R
Sbjct: 420 DCDSVTGKCT---CAPGFKGIDCSTPCPLGTYGINCSSR 455



>gi|38014361|gb|AAH01518.2|   POM121 protein [Homo sapiens]
          Length = 326

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 75/294 (25%), Positives = 109/294 (37%), Gaps = 61/294 (20%)

Query: 89  SDRTKPFFSLGLGAPGKAEDKS---GDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPL 145
           S+ + P F++  G+  K+   S    + Q A G+ +E  PPG               KP 
Sbjct: 18  SNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGA-AEGQPPGA-------------AKPA 63

Query: 146 FSFEFGAT---GEDEDKSRERWDAGNSRSEDSPA--------VGTGSSGLKLGAGKGDAA 194
            +  FG++   G     +     A  S  +  PA        +  G++    G     +A
Sbjct: 64  LAPSFGSSFTFGNSAAPAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASA 123

Query: 195 FGFEVSDSNSFGDT-------GISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGS 247
           FG   S   +FG +         SS      QT+SSG S S+  G T+    + F  GGS
Sbjct: 124 FGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSV-FGSTT---PSPFTFGGS 179

Query: 248 LNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETK 307
                    +G   FGIN        GS +    F  FG+  S S   S  F  GLG+  
Sbjct: 180 AAP------AGSGSFGINV----ATPGSSTTTGAFS-FGAGQSGSTATSTPFAGGLGQNA 228

Query: 308 GGA-------EFNFRDSGSNQSGDNGNSSKDFDGN----GVGDSSARNGFENSS 350
            G         FN   +  ++    G ++  F  N    GVG S +   F  SS
Sbjct: 229 LGTTGQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASS 282



>gi|14714613|gb|AAH10444.1|   MATN2 protein [Homo sapiens]
          Length = 937

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 82/405 (20%), Positives = 147/405 (36%), Gaps = 89/405 (21%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I G+Y  +C +   L++D     I + C   D    C+      +LC +  PG+F  
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--CE------QLCVNV-PGSF-- 301

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQDSECVSGCTCPEDKIQIFNA 609
                  VC   +C   +   E G    A   C++     + ECV             NA
Sbjct: 302 -------VC---QCYSGYALAEDGKRCVAVDYCASENHGCEHECV-------------NA 338

Query: 610 SSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-VGLCGSYNNKAEDDFMSSQNI 667
             SYL Q    F                ++ P++ T T +  C S N+  + + +++ + 
Sbjct: 339 DGSYLCQCHEGF----------------ALNPDEKTCTKIDYCASSNHGCQHECVNTDDS 382

Query: 668 LE-KTSQAFANSWEMMSCPK---------GNPSSCISIEKEKFAERHCGILLDSSGPLAS 717
                 + F  + +  +C +         G    C+++E+  +   H G  LD +G   +
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG--KT 440

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVKACAEKETYIVGWRTGLCEHS 774
           C  + +       C++     E+S  C C+   ++   +K C+  +  ++      CE+S
Sbjct: 441 CSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYS 498

Query: 775 -----------CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG---CTCPDAMYQ 820
                      CP G V + + K C +   S +  D  C+   V  +    C C +    
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYIL 557

Query: 821 NNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ 864
             +G  C  K  C     D   +   +   D   C C +G  L +
Sbjct: 558 REDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEGFRLAE 600



>gi|18044366|gb|AAH20198.1|   MEGF10 protein [Homo sapiens]
          Length = 567

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 55/194 (28%), Positives = 72/194 (37%), Gaps = 47/194 (24%)

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPS 777
           C+   +P  Y E C++  C+C+N  DC          +   K T   G++   C   CP 
Sbjct: 396 CNETCSPGFYGEACQQI-CSCQNGADC---------DSVTGKCTCAPGFKGIDCSTPCPL 445

Query: 778 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCP------DAMYQNNEG----NC 826
           G    Y +  C+S C    + D  C     PVDG CTC       D   +   G     C
Sbjct: 446 G---TYGIN-CSSRCG--CKNDAVCS----PVDGSCTCKAGWHGVDCSIRCPSGTWGFGC 495

Query: 827 VLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGIL--LCQIPI-DLTL-QNCSGGAEYVD 882
            L  QC   +N      G   +  D  C C  G     C++P  D T   NC   AE  D
Sbjct: 496 NLTCQC---LN------GGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNC---AERCD 543

Query: 883 CSDPKAQRRTNRTC 896
           CS       T   C
Sbjct: 544 CSHADGCHPTTGHC 557



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 53/219 (24%), Positives = 73/219 (33%), Gaps = 34/219 (15%)

Query: 684 CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 743
           CP+G      S E     + H G   D++     C P    +   +EC   T     ++ 
Sbjct: 268 CPEGRFGKNCSQE----CQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAET 323

Query: 744 CLCTILGN--YVKACAEKETYIVGWRTGLCE-HSCPSGLVFKYNVKACNSSCRSLSERDR 800
           C C   G   +V      E    G R   CE   CP GL   Y +K C+  C    E   
Sbjct: 324 CQCVNGGKCYHVSGACLCEAGFAGER---CEARLCPEGL---YGIK-CDKRCPCHLENTH 376

Query: 801 SCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGI 860
           SC     P+ G              C  K        +E   PG         C C++G 
Sbjct: 377 SCH----PMSG-------------ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419

Query: 861 LLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTR 899
               +    T   C+ G + +DCS P         CS+R
Sbjct: 420 DCDSVTGKCT---CAPGFKGIDCSTPCPLGTYGINCSSR 455



>gi|32425428|gb|AAH16394.1|   MATN2 protein [Homo sapiens]
          Length = 715

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 82/405 (20%), Positives = 147/405 (36%), Gaps = 89/405 (21%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I G+Y  +C +   L++D     I + C   D    C+      +LC +  PG+F  
Sbjct: 12  CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--CE------QLCVNV-PGSF-- 60

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQDSECVSGCTCPEDKIQIFNA 609
                  VC   +C   +   E G    A   C++     + ECV             NA
Sbjct: 61  -------VC---QCYSGYALAEDGKRCVAVDYCASENHGCEHECV-------------NA 97

Query: 610 SSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-VGLCGSYNNKAEDDFMSSQNI 667
             SYL Q    F                ++ P++ T T +  C S N+  + + +++ + 
Sbjct: 98  DGSYLCQCHEGF----------------ALNPDEKTCTKIDYCASSNHGCQHECVNTDDS 141

Query: 668 LE-KTSQAFANSWEMMSCPK---------GNPSSCISIEKEKFAERHCGILLDSSGPLAS 717
                 + F  + +  +C +         G    C+++E+  +   H G  LD +G   +
Sbjct: 142 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG--KT 199

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVKACAEKETYIVGWRTGLCEHS 774
           C  + +       C++     E+S  C C+   ++   +K C+  +  ++      CE+S
Sbjct: 200 CSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYS 257

Query: 775 -----------CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG---CTCPDAMYQ 820
                      CP G V + + K C +   S +  D  C+   V  +    C C +    
Sbjct: 258 CVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYIL 316

Query: 821 NNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ 864
             +G  C  K  C     D   +   +   D   C C +G  L +
Sbjct: 317 REDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEGFRLAE 359



>gi|21327701|ref|NP_631961.1|   TBP-associated factor 15 isoform 1 [Homo sapiens]
 gi|3763906|dbj|BAA33811.1|   RBP56/hTAFII68 [Homo sapiens]
 gi|1613775|gb|AAC50932.1|   putative RNA binding protein RBP56
 gi|8928305|sp|Q92804|RB56_HUMAN   TATA-binding protein associated factor 2N (RNA-binding protein 56)
           (TAFII68) (TAF(II)68)
          Length = 592

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 46/180 (25%), Positives = 59/180 (32%), Gaps = 26/180 (14%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD--N 325
           GG+        E G++G G                 G+  GG     R SG   SGD   
Sbjct: 391 GGDFRGRGYGGERGYRGRGGRGGDRGGYG-------GDRSGGGYGGDRSSGGGYSGDRSG 443

Query: 326 GNSSKDFDGNGV-GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPD 384
           G    D  G G  GD     G +   G   D G   G       +    GG+R      D
Sbjct: 444 GGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG------DRGGYGGDRGGGYGGD 497

Query: 385 EAGNLSPGSDVSDSGGNT--WSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
             G    G D    GG+   +  D G  GG +S      G  G +  G +G  G   G +
Sbjct: 498 RGGY---GGDRGGYGGDRGGYGGDRGGYGGDRSR-----GGYGGDRGGGSGYGGDRSGGY 549



>gi|55662302|emb|CAH72941.1|   novel protein similar to mouse Jedi soluble isoform 736 protein
           [Homo sapiens]
 gi|55662090|emb|CAH70011.1|   novel protein similar to mouse Jedi soluble isoform 736 protein
           [Homo sapiens]
          Length = 1037

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 51/194 (26%), Positives = 73/194 (37%), Gaps = 54/194 (27%)

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPS 777
           C  +  P  Y   C    C+CEN+  C   I G  V  C E      GW+ G C   CP 
Sbjct: 434 CASLCPPDTYGVNCSA-RCSCENAIAC-SPIDGECV--CKE------GWQRGNCSVPCPP 483

Query: 778 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-----------PDAMYQNNEGNC 826
           G  + +   +CN+SC+   E      V       CTC           P    Q  EG  
Sbjct: 484 G-TWGF---SCNASCQCAHEA-----VCSPQTGACTCTPGWHGAHCQLPCPKGQFGEG-- 532

Query: 827 VLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDP 886
              S+CDC  +D        +H    +C C+ G +  +  +     +C  G   V+CS+ 
Sbjct: 533 -CASRCDCDHSDGC----DPVH---GRCQCQAGWMGARCHL-----SCPEGLWGVNCSN- 578

Query: 887 KAQRRTNRTCSTRN 900
                   TC+ +N
Sbjct: 579 --------TCTCKN 584



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 51/181 (28%), Positives = 60/181 (33%), Gaps = 44/181 (24%)

Query: 716 ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSC 775
           A CH       +   C   TCTC+N   CL    GN V  CA       G+R   C+ SC
Sbjct: 561 ARCHLSCPEGLWGVNCSN-TCTCKNGGTCL-PENGNCV--CAP------GFRGPSCQRSC 610

Query: 776 PSGLVFKYNV--KACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG----NCVLK 829
             G   K  V  K  N S    S     C      + G T PD       G    NC   
Sbjct: 611 QPGRYGKRCVPCKCANHSFCHPSNGTCYC------LAGWTGPDCSQPCPPGHWGENCAQT 664

Query: 830 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLT----LQNCSGGAEYVDCSD 885
            QC           G   H  D  C+C         P+  T    L+ C  G    +CS 
Sbjct: 665 CQC---------HHGGTCHPQDGSCIC---------PLGWTGHHCLEGCPLGTFGANCSQ 706

Query: 886 P 886
           P
Sbjct: 707 P 707



>gi|51458803|ref|XP_371320.2|   PREDICTED: FLJ00193 protein [Homo sapiens]
          Length = 1429

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 51/194 (26%), Positives = 73/194 (37%), Gaps = 54/194 (27%)

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPS 777
           C  +  P  Y   C    C+CEN+  C   I G  V  C E      GW+ G C   CP 
Sbjct: 785 CASLCPPDTYGVNCSA-RCSCENAIAC-SPIDGECV--CKE------GWQRGNCSVPCPP 834

Query: 778 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTC-----------PDAMYQNNEGNC 826
           G  + +   +CN+SC+   E      V       CTC           P    Q  EG  
Sbjct: 835 G-TWGF---SCNASCQCAHEA-----VCSPQTGACTCTPGWHGAHCQLPCPKGQFGEG-- 883

Query: 827 VLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDP 886
              S+CDC  +D        +H    +C C+ G +  +  +     +C  G   V+CS+ 
Sbjct: 884 -CASRCDCDHSDGC----DPVH---GRCQCQAGWMGARCHL-----SCPEGLWGVNCSN- 929

Query: 887 KAQRRTNRTCSTRN 900
                   TC+ +N
Sbjct: 930 --------TCTCKN 935



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 45/150 (30%), Positives = 53/150 (35%), Gaps = 31/150 (20%)

Query: 716  ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSC 775
            A CH       +   C   TCTC+N   CL    GN V  CA       G+R   C+ SC
Sbjct: 912  ARCHLSCPEGLWGVNCSN-TCTCKNGGTCL-PENGNCV--CAP------GFRGPSCQRSC 961

Query: 776  PSGLVFKYNV--KACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG----NCVLK 829
              G   K  V  K  N S    S     C      + G T PD   +   G    NC   
Sbjct: 962  QPGRYGKRCVPCKCANHSFCHPSNGTCYC------LAGWTGPDCSQRCPLGTFGANCSQP 1015

Query: 830  SQCDCYINDEVMQPGKLIHIDDNKCVCRDG 859
             QC          PG+  H +   CVC  G
Sbjct: 1016 CQCG---------PGEKCHPETGACVCPPG 1036



>gi|28279785|gb|AAH46099.1|   TAF15 protein [Homo sapiens]
          Length = 501

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 46/180 (25%), Positives = 59/180 (32%), Gaps = 26/180 (14%)

Query: 268 GGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD--N 325
           GG+        E G++G G                 G+  GG     R SG   SGD   
Sbjct: 300 GGDFRGRGYGGERGYRGRGGRGGDRGGYG-------GDRSGGGYGGDRSSGGGYSGDRSG 352

Query: 326 GNSSKDFDGNGV-GDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPD 384
           G    D  G G  GD     G +   G   D G   G       +    GG+R      D
Sbjct: 353 GGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGG------DRGGYGGDRGGGYGGD 406

Query: 385 EAGNLSPGSDVSDSGGNT--WSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
             G    G D    GG+   +  D G  GG +S      G  G +  G +G  G   G +
Sbjct: 407 RGGY---GGDRGGYGGDRGGYGGDRGGYGGDRSR-----GGYGGDRGGGSGYGGDRSGGY 458



>gi|13518039|ref|NP_085072.1|   matrilin 2 precursor [Homo sapiens]
          Length = 937

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 82/405 (20%), Positives = 147/405 (36%), Gaps = 89/405 (21%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I G+Y  +C +   L++D     I + C   D    C+      +LC +  PG+F  
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--CE------QLCVNV-PGSF-- 301

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQDSECVSGCTCPEDKIQIFNA 609
                  VC   +C   +   E G    A   C++     + ECV             NA
Sbjct: 302 -------VC---QCYSGYALAEDGKRCVAVDYCASENHGCEHECV-------------NA 338

Query: 610 SSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-VGLCGSYNNKAEDDFMSSQNI 667
             SYL Q    F                ++ P++ T T +  C S N+  + + +++ + 
Sbjct: 339 DGSYLCQCHEGF----------------ALNPDEKTCTKIDYCASSNHGCQHECVNTDDS 382

Query: 668 LE-KTSQAFANSWEMMSCPK---------GNPSSCISIEKEKFAERHCGILLDSSGPLAS 717
                 + F  + +  +C +         G    C+++E+  +   H G  LD +G   +
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG--KT 440

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVKACAEKETYIVGWRTGLCEHS 774
           C  + +       C++     E+S  C C+   ++   +K C+  +  ++      CE+S
Sbjct: 441 CSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYS 498

Query: 775 -----------CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG---CTCPDAMYQ 820
                      CP G V + + K C +   S +  D  C+   V  +    C C +    
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYIL 557

Query: 821 NNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ 864
             +G  C  K  C     D   +   +   D   C C +G  L +
Sbjct: 558 REDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEGFRLAE 600



>gi|13518037|ref|NP_002371.2|   matrilin 2 precursor [Homo sapiens]
          Length = 956

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 82/405 (20%), Positives = 147/405 (36%), Gaps = 89/405 (21%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I G+Y  +C +   L++D     I + C   D    C+      +LC +  PG+F  
Sbjct: 253 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--CE------QLCVNV-PGSF-- 301

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQDSECVSGCTCPEDKIQIFNA 609
                  VC   +C   +   E G    A   C++     + ECV             NA
Sbjct: 302 -------VC---QCYSGYALAEDGKRCVAVDYCASENHGCEHECV-------------NA 338

Query: 610 SSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-VGLCGSYNNKAEDDFMSSQNI 667
             SYL Q    F                ++ P++ T T +  C S N+  + + +++ + 
Sbjct: 339 DGSYLCQCHEGF----------------ALNPDEKTCTKIDYCASSNHGCQHECVNTDDS 382

Query: 668 LE-KTSQAFANSWEMMSCPK---------GNPSSCISIEKEKFAERHCGILLDSSGPLAS 717
                 + F  + +  +C +         G    C+++E+  +   H G  LD +G   +
Sbjct: 383 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG--KT 440

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVKACAEKETYIVGWRTGLCEHS 774
           C  + +       C++     E+S  C C+   ++   +K C+  +  ++      CE+S
Sbjct: 441 CSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYS 498

Query: 775 -----------CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG---CTCPDAMYQ 820
                      CP G V + + K C +   S +  D  C+   V  +    C C +    
Sbjct: 499 CVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYIL 557

Query: 821 NNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ 864
             +G  C  K  C     D   +   +   D   C C +G  L +
Sbjct: 558 REDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEGFRLAE 600



>gi|21739491|emb|CAD38787.1|   hypothetical protein [Homo sapiens]
          Length = 1016

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 82/405 (20%), Positives = 147/405 (36%), Gaps = 89/405 (21%)

Query: 492 CNKIIGTYFEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFES 551
           C  I G+Y  +C +   L++D     I + C   D    C+      +LC +  PG+F  
Sbjct: 313 CINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHN--CE------QLCVNV-PGSF-- 361

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPAT--CSNVAPFQDSECVSGCTCPEDKIQIFNA 609
                  VC   +C   +   E G    A   C++     + ECV             NA
Sbjct: 362 -------VC---QCYSGYALAEDGKRCVAVDYCASENHGCEHECV-------------NA 398

Query: 610 SSSYL-QVETYFHVKLQIQIVPVMQLYVSMPPNQFTDT-VGLCGSYNNKAEDDFMSSQNI 667
             SYL Q    F                ++ P++ T T +  C S N+  + + +++ + 
Sbjct: 399 DGSYLCQCHEGF----------------ALNPDEKTCTKIDYCASSNHGCQHECVNTDDS 442

Query: 668 LE-KTSQAFANSWEMMSCPK---------GNPSSCISIEKEKFAERHCGILLDSSGPLAS 717
                 + F  + +  +C +         G    C+++E+  +   H G  LD +G   +
Sbjct: 443 YSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNG--KT 500

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCT---ILGNYVKACAEKETYIVGWRTGLCEHS 774
           C  + +       C++     E+S  C C+   ++   +K C+  +  ++      CE+S
Sbjct: 501 CSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHG--CEYS 558

Query: 775 -----------CPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG---CTCPDAMYQ 820
                      CP G V + + K C +   S +  D  C+   V  +    C C +    
Sbjct: 559 CVNMDRSFACQCPEGHVLRSDGKTC-AKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYIL 617

Query: 821 NNEG-NCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQ 864
             +G  C  K  C     D   +   +   D   C C +G  L +
Sbjct: 618 REDGKTCRRKDVCQAI--DHGCEHICVNSDDSYTCECLEGFRLAE 660



>gi|21307718|gb|AAK62026.1|   GW182 autoantigen [Homo sapiens]
 gi|21702742|ref|NP_055309.1|   trinucleotide repeat containing 6A [Homo sapiens]
          Length = 1709

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 21/191 (10%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG- 374
           DS S+   +  N +    GN  G+   ++G  NS+G+   +  ++GSS  +    S TG 
Sbjct: 4   DSASSSESER-NITIMASGNTGGE---KDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGP 59

Query: 375 ---------GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                       + S D  E+      S+ S++  N W + S S  GG +   L   AS 
Sbjct: 60  WGFSHGAIISTCQVSVDAPES-----KSESSNNRMNAWGTVSSSSNGGLNPSTLN-SASN 113

Query: 426 LNEFGETGLSGSEKGSHIPEATPKYSETNAIIGQDINEHIANSKIPGDCPNAV-GKSYEV 484
              +     +G      +   +   +   + IGQ  N    NSK+ G   +   G   E 
Sbjct: 114 HGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQET 173

Query: 485 CEDGIQHCNKI 495
           CE  +    K+
Sbjct: 174 CESEVSGTQKV 184



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 49/190 (25%)

Query: 105 KAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERW 164
           + E K+ +  +A GS +  T         +S    DK  P  +     +G  + K   RW
Sbjct: 488 RGERKTDNGTEAWGSSATQT--------FNSGACIDKTSPNGNDTSSVSGWGDPKPALRW 539

Query: 165 DAGNSRS--------EDSPAVGTGSSGL-----------------KLGAGKGD-AAFGFE 198
             G+S+         +DS A G   S                   K G G G  ++ G+ 
Sbjct: 540 --GDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWS 597

Query: 199 VSDSNSFGDTGISSKTVEGNQTSSSGGSVS-------IDLGDTSFRSENQFVGGGSLN-S 250
           VS S+++G+T  ++   E N+ SSSGGS S        +LG TS      F  G ++N +
Sbjct: 598 VSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTS-----SFTWGNNINPN 652

Query: 251 ISNLWDSGQE 260
            S+ WD   +
Sbjct: 653 NSSGWDESSK 662



>gi|186629|gb|AAA59199.1|   keratin 10
          Length = 384

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 41/125 (32%), Positives = 49/125 (39%), Gaps = 21/125 (16%)

Query: 178 GTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFR 237
           G GSSG   G G+G  +FG      +S G +        G    SSGG      G +   
Sbjct: 259 GEGSSG---GGGRGGGSFGGGYGGGSSGGGSS------GGGHGGSSGGGYGG--GSSGGG 307

Query: 238 SENQFVGGGSLNSISNLWDSGQEGFGINEIG------GNGMSGSVSAEAGFKGFGSDSSS 291
           S     GGGS  S      S   G+G    G      G G SG  S+  G  G+G  SSS
Sbjct: 308 SSGGGYGGGS--SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGG--GYGGGSSS 363

Query: 292 SVEKS 296
              KS
Sbjct: 364 GGHKS 368



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 39/136 (28%), Positives = 47/136 (34%), Gaps = 10/136 (7%)

Query: 302 GLGETKGGAEFNFRDSGSNQSGDNGNSSKD-FDGNGVGDSSARNGFENSSGISEDSGVIL 360
           GL E +G +    R  GS   G  G SS     G G G SS       SSG     G   
Sbjct: 255 GLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGSSGGGYGGGSSGGGSSGGGYG 314

Query: 361 GSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG 420
           G S         + G    SS     G  S G      GG++    S  GG G  +   G
Sbjct: 315 GGS---------SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 365

Query: 421 VGASGLNEFGETGLSG 436
             +S     GE+   G
Sbjct: 366 HKSSSSGSVGESSSKG 381



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 39/124 (31%), Positives = 43/124 (34%), Gaps = 13/124 (10%)

Query: 318 GSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNR 377
           G   SG  G     F G   G SS         G S   G   GSS       S  GG  
Sbjct: 259 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGSSGGGYGGGSSGGG----SSGGGYG 314

Query: 378 KRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGS 437
             SS     G+ S G     SGG       G G GG S+   G G+S    +G    SG 
Sbjct: 315 GGSSSGGHGGSSSGGYGGGSSGGG------GGGYGGGSS---GGGSSSGGGYGGGSSSGG 365

Query: 438 EKGS 441
            K S
Sbjct: 366 HKSS 369



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 35/125 (28%), Positives = 43/125 (34%), Gaps = 16/125 (12%)

Query: 26  SGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSS 85
           S G  YG  SSG             GS G     S      G      +  GG+   SSS
Sbjct: 272 SFGGGYGGGSSGG------------GSSGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 319

Query: 86  SGDSDRTKPFF---SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS-GDSDK 141
            G    +   +   S G G  G     SG    +GG     +  GG    SS S G+S  
Sbjct: 320 GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSS 379

Query: 142 KKPLF 146
           K P +
Sbjct: 380 KGPRY 384



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 17/44 (38%), Positives = 20/44 (45%)

Query: 399 GGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           GG++    SG G GG S    G G+SG    G     GS  G H
Sbjct: 279 GGSSGGGSSGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGH 322



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 35/138 (25%), Positives = 46/138 (33%), Gaps = 22/138 (15%)

Query: 78  GFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDA-------GGSKSEDTPPGGFF 130
           G      SSG   R    F  G G        SG            GGS    +  GG+ 
Sbjct: 255 GLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGSSGGGYGGGSSGGGSSGGGYG 314

Query: 131 YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
            GSSS G          +  G++G            G      S   G+ S G   G G 
Sbjct: 315 GGSSSGGHGGSSSG--GYGGGSSG----------GGGGGYGGGSSGGGSSSGG---GYGG 359

Query: 191 GDAAFGFEVSDSNSFGDT 208
           G ++ G + S S S G++
Sbjct: 360 GSSSGGHKSSSSGSVGES 377



>gi|21702733|ref|NP_065898.1|   trinucleotide repeat containing 6A [Homo sapiens]
 gi|21693029|emb|CAD37348.1|   EDIE protein [Homo sapiens]
          Length = 1962

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 21/191 (10%)

Query: 316 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTG- 374
           DS S+   +  N +    GN  G+   ++G  NS+G+   +  ++GSS  +    S TG 
Sbjct: 257 DSASSSESER-NITIMASGNTGGE---KDGLRNSTGLGSQNKFVVGSSSNNVGHGSSTGP 312

Query: 375 ---------GNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASG 425
                       + S D  E+      S+ S++  N W + S S  GG +   L   AS 
Sbjct: 313 WGFSHGAIISTCQVSVDAPES-----KSESSNNRMNAWGTVSSSSNGGLNPSTLN-SASN 366

Query: 426 LNEFGETGLSGSEKGSHIPEATPKYSETNAIIGQDINEHIANSKIPGDCPNAV-GKSYEV 484
              +     +G      +   +   +   + IGQ  N    NSK+ G   +   G   E 
Sbjct: 367 HGAWPVLENNGLALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSLQET 426

Query: 485 CEDGIQHCNKI 495
           CE  +    K+
Sbjct: 427 CESEVSGTQKV 437



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 49/190 (25%)

Query: 105 KAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERW 164
           + E K+ +  +A GS +  T         +S    DK  P  +     +G  + K   RW
Sbjct: 741 RGERKTDNGTEAWGSSATQT--------FNSGACIDKTSPNGNDTSSVSGWGDPKPALRW 792

Query: 165 DAGNSRS--------EDSPAVGTGSSGL-----------------KLGAGKGD-AAFGFE 198
             G+S+         +DS A G   S                   K G G G  ++ G+ 
Sbjct: 793 --GDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWS 850

Query: 199 VSDSNSFGDTGISSKTVEGNQTSSSGGSVS-------IDLGDTSFRSENQFVGGGSLN-S 250
           VS S+++G+T  ++   E N+ SSSGGS S        +LG TS      F  G ++N +
Sbjct: 851 VSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTS-----SFTWGNNINPN 905

Query: 251 ISNLWDSGQE 260
            S+ WD   +
Sbjct: 906 NSSGWDESSK 915



>gi|55741878|ref|NP_065798.1|   zinc finger protein 608 [Homo sapiens]
          Length = 1512

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 12/156 (7%)

Query: 287 SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGF 346
           + SS+S +       G G T   A+   + +    S   GNS K+   + V  S      
Sbjct: 57  TSSSNSKDCGGPASSGAGATAALAD-GLKFASVQASAPQGNSHKETSKSKVKRSKT---- 111

Query: 347 ENSSGISEDSGVILGSSDQHEV-ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
                 S+D+   L S+  + + E+S TG  ++    P EA  ++     S S G + + 
Sbjct: 112 ------SKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNP 165

Query: 406 DSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           +S S     SA   G G+ G ++  + G S S +G+
Sbjct: 166 NSNSTSTSTSAATAGAGSCGKSKEEKPGKSQSSRGA 201



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 57/287 (19%), Positives = 97/287 (33%), Gaps = 54/287 (18%)

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
           D +K R++++  NS +       T SS  K   G   +  G   + ++      + +   
Sbjct: 40  DLEKDRQKFEMNNSTTT------TSSSNSKDCGGPASSGAGATAALADGLKFASVQASAP 93

Query: 216 EGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS 275
           +GN    +  S  +    TS +  N+ +   +L             +GI EI   G    
Sbjct: 94  QGNSHKETSKS-KVKRSKTS-KDANKSLPSAAL-------------YGIPEISSTGKRQE 138

Query: 276 VSAEAG-FKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           V    G   G  S    SV        G G     +      + +  +G  G S ++  G
Sbjct: 139 VQGRPGEATGMNSALGQSVSSG-----GSGNPNSNSTSTSTSAATAGAGSCGKSKEEKPG 193

Query: 335 NGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD 394
                       ++S G   D        D+H++      G+          G+ +P   
Sbjct: 194 KS----------QSSRGAKRDKDAGKSRKDKHDLLQGHQNGS----------GSQAP--- 230

Query: 395 VSDSGGNTWSSDSGSGGGGKSADELG-VGASGLNEFGETGLSGSEKG 440
              SGG+ +   + S GGG S    G  G+  +   GE   S  + G
Sbjct: 231 ---SGGHLYGFGAKSNGGGASPFHCGGTGSGSVAAAGEVSKSAPDSG 274



>gi|50660400|gb|AAT80901.1|   striated muscle preferentially expressed protein [Homo sapiens]
          Length = 3094

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 27/173 (15%)

Query: 76   AGGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGF 129
            A G    SS  G S R  P        S  L        +SG S+D+GG+    TP  G 
Sbjct: 2302 ARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSSEDSGGASGRSTPLFGR 2361

Query: 130  FYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
               ++S G+S ++  L   +  A       S E   +  S +  S A G   S L+ G  
Sbjct: 2362 LRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGF- 2420

Query: 190  KGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQF 242
                        S    D G+S   +          SV  +LG    RSE+ F
Sbjct: 2421 ------------SRPRKDKGLSPPNL--------SASVQEELGHQYVRSESDF 2453



>gi|27894378|ref|NP_444507.1|   chloride intracellular channel 6 [Homo sapiens]
 gi|25990942|gb|AAN76729.1|   chloride channel form A [Homo sapiens]
          Length = 686

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 61/255 (23%), Positives = 98/255 (38%), Gaps = 46/255 (18%)

Query: 51  GSPGETEDKS-RQRQDAGSPK----SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPG- 104
           G+ GE   ++ R+ +D+ +P+    +E  P     ++S  +GDS   +      + A G 
Sbjct: 116 GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGP 175

Query: 105 -----KAEDKSGDSQDA----GGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGE 155
                +AE + GDS DA    G S   + P G        +GDS   +        A G 
Sbjct: 176 AGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGP 235

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA--AFGFEVSDSNSFGDTGISSK 213
             D        G+S     PA      G++ G   GD+  A G      ++ G  G  ++
Sbjct: 236 AGDSVDAEGRVGDSVEAGDPA----GDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG-RAR 290

Query: 214 TVEGNQTSSSGGSVS-------IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE 266
            V G    S  GS+S       +  G+++ RS  +             WD+ +E     E
Sbjct: 291 RVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELA-----------WDAAEEA----E 335

Query: 267 IGGNGMSGSVSAEAG 281
           +   G+ GS  A  G
Sbjct: 336 V--PGVKGSEEAAPG 348



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 77/365 (21%), Positives = 133/365 (36%), Gaps = 44/365 (12%)

Query: 51  GSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGL---------- 100
           G PG    ++   +  GS  +E+ P G      +  G  DR     + G           
Sbjct: 29  GEPGAAGGEAEGPE--GSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAE 86

Query: 101 -GAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDK 159
            GAP  AE   G  + +G  + E   PG    G    G++ ++             ++  
Sbjct: 87  EGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG-EPRGEAQRE------------PEDSA 133

Query: 160 SRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQ 219
           + ER +    R E      +G +G  + A   +   G  +      GD+  +   V  + 
Sbjct: 134 APERQEEAEQRPEVPEGSASGEAGDSVDA---EGPLGDNIEAEGPAGDSVEAEGRVGDSV 190

Query: 220 TSSSGGSVSIDL-GDTSFRSENQFVGGGSLNSISNLWDS-GQEGFGINEIGGNGMSGSVS 277
            +      S+D  G      + +   G S+++   + DS   EG   + +   G  G  S
Sbjct: 191 DAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGD-S 249

Query: 278 AEAGF-KGFGSDSSSSVEKSWLFEFGLGET---KGGAEFNFRDSGSNQSGDNGNSSKDFD 333
            EAG   G G ++      S   E   G++   +G A    R SG  Q   +G+ S   +
Sbjct: 250 VEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAE 309

Query: 334 GNGV--GDSSARNGFENSSGISEDSGV--ILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
              V  G+S+ R+  E +   +E++ V  + GS +    +     G  +    P +    
Sbjct: 310 AIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQ---- 365

Query: 390 SPGSD 394
            PG D
Sbjct: 366 EPGED 370



>gi|25990944|gb|AAN76730.1|   chloride channel form B [Homo sapiens]
 gi|38372885|sp|Q96NY7|CLIC6_HUMAN   Chloride intracellular channel 6
          Length = 704

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 61/255 (23%), Positives = 98/255 (38%), Gaps = 46/255 (18%)

Query: 51  GSPGETEDKS-RQRQDAGSPK----SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPG- 104
           G+ GE   ++ R+ +D+ +P+    +E  P     ++S  +GDS   +      + A G 
Sbjct: 116 GAQGEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGP 175

Query: 105 -----KAEDKSGDSQDA----GGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGE 155
                +AE + GDS DA    G S   + P G        +GDS   +        A G 
Sbjct: 176 AGDSVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGP 235

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDA--AFGFEVSDSNSFGDTGISSK 213
             D        G+S     PA      G++ G   GD+  A G      ++ G  G  ++
Sbjct: 236 AGDSVDAEGRVGDSVEAGDPA----GDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG-RAR 290

Query: 214 TVEGNQTSSSGGSVS-------IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINE 266
            V G    S  GS+S       +  G+++ RS  +             WD+ +E     E
Sbjct: 291 RVSGEPQQSGDGSLSPQAEAIEVAAGESAGRSPGELA-----------WDAAEEA----E 335

Query: 267 IGGNGMSGSVSAEAG 281
           +   G+ GS  A  G
Sbjct: 336 V--PGVKGSEEAAPG 348



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 77/365 (21%), Positives = 133/365 (36%), Gaps = 44/365 (12%)

Query: 51  GSPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGL---------- 100
           G PG    ++   +  GS  +E+ P G      +  G  DR     + G           
Sbjct: 29  GEPGAAGGEAEGPE--GSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAE 86

Query: 101 -GAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDK 159
            GAP  AE   G  + +G  + E   PG    G    G++ ++             ++  
Sbjct: 87  EGAPEGAEVPQGGEETSGAQQVEGASPGRGAQG-EPRGEAQRE------------PEDSA 133

Query: 160 SRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQ 219
           + ER +    R E      +G +G  + A   +   G  +      GD+  +   V  + 
Sbjct: 134 APERQEEAEQRPEVPEGSASGEAGDSVDA---EGPLGDNIEAEGPAGDSVEAEGRVGDSV 190

Query: 220 TSSSGGSVSIDL-GDTSFRSENQFVGGGSLNSISNLWDS-GQEGFGINEIGGNGMSGSVS 277
            +      S+D  G      + +   G S+++   + DS   EG   + +   G  G  S
Sbjct: 191 DAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGDSVDAEGRVGD-S 249

Query: 278 AEAGF-KGFGSDSSSSVEKSWLFEFGLGET---KGGAEFNFRDSGSNQSGDNGNSSKDFD 333
            EAG   G G ++      S   E   G++   +G A    R SG  Q   +G+ S   +
Sbjct: 250 VEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAE 309

Query: 334 GNGV--GDSSARNGFENSSGISEDSGV--ILGSSDQHEVELSRTGGNRKRSSDPDEAGNL 389
              V  G+S+ R+  E +   +E++ V  + GS +    +     G  +    P +    
Sbjct: 310 AIEVAAGESAGRSPGELAWDAAEEAEVPGVKGSEEAAPGDARADAGEDRVGDGPQQ---- 365

Query: 390 SPGSD 394
            PG D
Sbjct: 366 EPGED 370



>gi|52545626|emb|CAB70853.2|   hypothetical protein [Homo sapiens]
          Length = 672

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 41/196 (20%), Positives = 74/196 (37%), Gaps = 25/196 (12%)

Query: 687 GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
           G    C+++E+  +   H G  LD +G   +C  + +       C++     E+S  C C
Sbjct: 128 GCEHECVNMEESYYCRCHRGYTLDPNG--KTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 185

Query: 747 T---ILGNYVKACAEKETYIVGWRTGLCEHS-----------CPSGLVFKYNVKACNSSC 792
           +   ++   +K C+  +  ++      CE+S           CP G V + + K C +  
Sbjct: 186 SEGFLINEDLKTCSRVDYCLLSDHG--CEYSCVNMDRSFACQCPEGHVLRSDGKTC-AKL 242

Query: 793 RSLSERDRSCDVEDVPVDG---CTCPDAMYQNNEG-NCVLKSQCDCYINDEVMQPGKLIH 848
            S +  D  C+   V  +    C C +      +G  C  K  C     D   +   +  
Sbjct: 243 DSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAI--DHGCEHICVNS 300

Query: 849 IDDNKCVCRDGILLCQ 864
            D   C C +G  L +
Sbjct: 301 DDSYTCECLEGFRLAE 316



>gi|51476585|emb|CAH18275.1|   hypothetical protein [Homo sapiens]
          Length = 1140

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 53/219 (24%), Positives = 73/219 (33%), Gaps = 34/219 (15%)

Query: 684 CPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 743
           CP+G      S E     + H G   D++     C P    +   +EC   T     ++ 
Sbjct: 268 CPEGRFGKNCSQE----CQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAET 323

Query: 744 CLCTILGN--YVKACAEKETYIVGWRTGLCE-HSCPSGLVFKYNVKACNSSCRSLSERDR 800
           C C   G   +V      E    G R   CE   CP GL   Y +K C+  C    E   
Sbjct: 324 CQCVNGGKCYHVSGACLCEAGFAGER---CEARLCPEGL---YGIK-CDKRCPCHLENTH 376

Query: 801 SCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGI 860
           SC     P+ G              C  K        +E   PG         C C++G 
Sbjct: 377 SCH----PMSG-------------ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419

Query: 861 LLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTR 899
               +    T   C+ G + +DCS P         CS+R
Sbjct: 420 DCDSVTGKCT---CAPGFKGIDCSTPCPLGTYGINCSSR 455



 Score = 36.6 bits (83), Expect = 0.30
 Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 49/181 (27%)

Query: 718 CHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPS 777
           C+   +P  Y E C++  C+C+N  DC          +   K T   G++   C   CP 
Sbjct: 396 CNETCSPGFYGEACQQI-CSCQNGADC---------DSVTGKCTCAPGFKGIDCSTPCPL 445

Query: 778 GLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDG-CTCP------DAMYQNNEG----NC 826
           G    Y +  C+S C    + D  C     PVDG CTC       D   +   G     C
Sbjct: 446 G---TYGIN-CSSRCG--CKNDAVCS----PVDGSCTCKAGWHGVDCSIRCPSGTWGFGC 495

Query: 827 VLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDGIL--LCQIPIDLTLQNCSGGAEYVDCS 884
            L  QC   +N      G   +  D  C C  G     C++P       C  G   ++C+
Sbjct: 496 NLTCQC---LN------GGACNTLDGTCTCAPGWRGEKCELP-------CQDGTYGLNCA 539

Query: 885 D 885
           +
Sbjct: 540 E 540



>gi|8699046|gb|AAF78570.1|   corneodesmosin [Homo sapiens]
 gi|8699044|gb|AAF78569.1|   corneodesmosin [Homo sapiens]
 gi|8699042|gb|AAF78568.1|   corneodesmosin [Homo sapiens]
          Length = 500

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 45/163 (27%), Positives = 59/163 (36%), Gaps = 17/163 (10%)

Query: 133 SSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGD 192
           SS SG S     + S      G     S      G S     P  GTG S +   +G G 
Sbjct: 37  SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP--GTGYSQVSYSSGSGS 94

Query: 193 AAFGFEVSDSNSFGDTGI---SSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLN 249
           +  G   S S+  G +     SS +  GN +S S  S S     +SF+  N    G +L 
Sbjct: 95  SLQG--ASGSSQLGSSSSHSGSSGSHSGNSSSHSSSSSSFQFSSSSFQVGN----GSALP 148

Query: 250 SISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSS 292
           +  N +       GI      G S S S   G    G   SS+
Sbjct: 149 TNDNSYR------GILNPSQPGQSSSSSQTFGVSSSGQSVSSN 185



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 34/136 (25%), Positives = 51/136 (37%), Gaps = 36/136 (26%)

Query: 320 NQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKR 379
           + SG +  S     G+ +  SSAR+    SSG S  S +  G S                
Sbjct: 32  DSSGFSSYSGSSSSGSSI--SSARSSGGGSSGSSSGSSIAQGGS---------------- 73

Query: 380 SSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLSGSEK 439
                 AG+  PG+         +S  S S G G S      GASG ++ G +       
Sbjct: 74  ------AGSFKPGTG--------YSQVSYSSGSGSSLQ----GASGSSQLGSSSSHSGSS 115

Query: 440 GSHIPEATPKYSETNA 455
           GSH   ++   S +++
Sbjct: 116 GSHSGNSSSHSSSSSS 131



>gi|7242949|dbj|BAA92535.1|   KIAA1297 protein [Homo sapiens]
          Length = 2242

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 45/173 (26%), Positives = 62/173 (35%), Gaps = 27/173 (15%)

Query: 76   AGGFFNSSSSSGDSDRTKPFF------SLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGF 129
            A G    SS  G S R  P        S  L        +SG S+D+GG+    TP  G 
Sbjct: 1450 ARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSSEDSGGASGRSTPLFGR 1509

Query: 130  FYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAG 189
               ++S G+S ++  L   +  A       S E   +  S +  S A G   S L+ G  
Sbjct: 1510 LRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGF- 1568

Query: 190  KGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQF 242
                        S    D G+S   +          SV  +LG    RSE+ F
Sbjct: 1569 ------------SRPRKDKGLSPPNL--------SASVQEELGHQYVRSESDF 1601



>gi|20521822|dbj|BAA86595.2|   KIAA1281 protein [Homo sapiens]
          Length = 1534

 Score = 37.0 bits (84), Expect = 0.23
 Identities = 39/156 (25%), Positives = 66/156 (42%), Gaps = 12/156 (7%)

Query: 287 SDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGF 346
           + SS+S +       G G T   A+   + +    S   GNS K+   + V  S      
Sbjct: 79  TSSSNSKDCGGPASSGAGATAALAD-GLKFASVQASAPQGNSHKETSKSKVKRSKT---- 133

Query: 347 ENSSGISEDSGVILGSSDQHEV-ELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
                 S+D+   L S+  + + E+S TG  ++    P EA  ++     S S G + + 
Sbjct: 134 ------SKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNP 187

Query: 406 DSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGS 441
           +S S     SA   G G+ G ++  + G S S +G+
Sbjct: 188 NSNSTSTSTSAATAGAGSCGKSKEEKPGKSQSSRGA 223



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 57/287 (19%), Positives = 97/287 (33%), Gaps = 54/287 (18%)

Query: 156 DEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTV 215
           D +K R++++  NS +       T SS  K   G   +  G   + ++      + +   
Sbjct: 62  DLEKDRQKFEMNNSTTT------TSSSNSKDCGGPASSGAGATAALADGLKFASVQASAP 115

Query: 216 EGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS 275
           +GN    +  S  +    TS +  N+ +   +L             +GI EI   G    
Sbjct: 116 QGNSHKETSKS-KVKRSKTS-KDANKSLPSAAL-------------YGIPEISSTGKRQE 160

Query: 276 VSAEAG-FKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
           V    G   G  S    SV        G G     +      + +  +G  G S ++  G
Sbjct: 161 VQGRPGEATGMNSALGQSVSSG-----GSGNPNSNSTSTSTSAATAGAGSCGKSKEEKPG 215

Query: 335 NGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSD 394
                       ++S G   D        D+H++      G+          G+ +P   
Sbjct: 216 KS----------QSSRGAKRDKDAGKSRKDKHDLLQGHQNGS----------GSQAP--- 252

Query: 395 VSDSGGNTWSSDSGSGGGGKSADELG-VGASGLNEFGETGLSGSEKG 440
              SGG+ +   + S GGG S    G  G+  +   GE   S  + G
Sbjct: 253 ---SGGHLYGFGAKSNGGGASPFHCGGTGSGSVAAAGEVSKSAPDSG 296



>gi|2765322|emb|CAA73867.1|   RB18A protein [Homo sapiens]
          Length = 1566

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 73/334 (21%), Positives = 113/334 (33%), Gaps = 36/334 (10%)

Query: 99   GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
            G G   K   +S    + G  KS+D PP           D++ K P  S           
Sbjct: 970  GPGLDSKPGKRSRTPSNDG--KSKDKPP------KRKKADTEGKSPSHSSSNRPFTPPTS 1021

Query: 159  KSRERWDAGNSRSEDSPAVGTGS-SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG 217
                +      RS+  P V T     + +   KG    G   S S       +SS   + 
Sbjct: 1022 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1081

Query: 218  NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVS 277
            + + SS  S S     TS + ++    G S + +S+   S Q   G ++   +  SG   
Sbjct: 1082 HHSHSSSSSSS---ASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1138

Query: 278  AEAGFKGFGSDSSSSVEK-------SWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              +     G  S SS  K       S L    L +       +    GS++     +  K
Sbjct: 1139 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA---SPMK 1195

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G     S A++   + SG S  SG             + +    K SS    +G+LS
Sbjct: 1196 PVPGTPPS-SKAKSPISSGSGGSHMSG-------------TSSSSGMKSSSGLGSSGSLS 1241

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
              +  S +     SS   S G   S+ +   G+S
Sbjct: 1242 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1275



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 66/307 (21%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            GK+ +S+S G S    SS        ++S + GS G ++ K+   Q  G P S      G
Sbjct: 1097 GKMKSSKSEGSSSSKLSSS-------MYSSQ-GSSGSSQSKNSS-QSGGKPGSSPITKHG 1147

Query: 79   FFNSSSSS-----------------------------GDSDRTKPFFSLGLGAPGKAEDK 109
              + SSS+                             G SD+         G P  ++ K
Sbjct: 1148 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1207

Query: 110  SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            S  S  +GGS    T        SSSSG         S   G++G    K+     + NS
Sbjct: 1208 SPISSGSGGSHMSGT--------SSSSGMKS------SSGLGSSGSLSQKTP---PSSNS 1250

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
             +  S +  +  S +     +  ++ G   S +     T +  K   G  TS  GG   +
Sbjct: 1251 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1310

Query: 230  DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS 289
            D G            G S NS S+   S     G    G    S    ++    G   DS
Sbjct: 1311 D-GQM----------GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1359

Query: 290  SSSVEKS 296
            S    +S
Sbjct: 1360 SKKTSES 1366



>gi|55958451|emb|CAI12730.1|   OTTHUMP00000018488 [Homo sapiens]
          Length = 276

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 40/150 (26%), Positives = 48/150 (32%), Gaps = 22/150 (14%)

Query: 284 GFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSAR 343
           G   +   ++ K  +   G     GG   NF   G N  G  GN      G G G+   R
Sbjct: 90  GHNCEVKKALSKQEMQSAGSQRGHGGGSGNFMGRGGNFGGAGGNF-----GLG-GNFGGR 143

Query: 344 NGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTW 403
            G+    G S  S    G  D       R GGN          G           GG  +
Sbjct: 144 GGYGGGGGGSRGS---YGRGDGGYNRFGRDGGNYGGGPGYSSRGGYG-------GGGTGY 193

Query: 404 SSDSGSGGGGKSADELGVGASGLNEFGETG 433
            +  G  GGG      G G  G NE G  G
Sbjct: 194 GNQGGGYGGG------GGGYDGYNEGGNFG 217



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 50/197 (25%), Positives = 69/197 (35%), Gaps = 29/197 (14%)

Query: 161 RERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQT 220
           +E   AG+ R         G SG  +G G      G       +FG  G       G++ 
Sbjct: 102 QEMQSAGSQRGHG------GGSGNFMGRGGNFGGAGGNFGLGGNFGGRGGYGGGGGGSRG 155

Query: 221 SSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA 280
           S   G    D G   F  +    GGG   S    +  G  G+G N+ GG G  G      
Sbjct: 156 SYGRG----DGGYNRFGRDGGNYGGGPGYSSRGGYGGGGTGYG-NQGGGYGGGGG----- 205

Query: 281 GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
           G+ G+    +          FG G   GG   N+ D G N SG   ++     G   G  
Sbjct: 206 GYDGYNEGGN----------FGGGNYGGGG--NYNDFG-NHSGQQQSNYGPMKGGSFGGR 252

Query: 341 SARNGFENSSGISEDSG 357
           S+ + +    G    SG
Sbjct: 253 SSGSPYGGGYGSGGGSG 269



>gi|51493076|ref|XP_370728.2|   PREDICTED: similar to heterogeneous nuclear ribonucleoprotein A3
           [Homo sapiens]
          Length = 319

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 40/150 (26%), Positives = 48/150 (32%), Gaps = 22/150 (14%)

Query: 284 GFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSAR 343
           G   +   ++ K  +   G     GG   NF   G N  G  GN      G G G+   R
Sbjct: 133 GHNCEVKKALSKQEMQSAGSQRGHGGGSGNFMGRGGNFGGAGGNF-----GLG-GNFGGR 186

Query: 344 NGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTW 403
            G+    G S  S    G  D       R GGN          G           GG  +
Sbjct: 187 GGYGGGGGGSRGS---YGRGDGGYNRFGRDGGNYGGGPGYSSRGGYG-------GGGTGY 236

Query: 404 SSDSGSGGGGKSADELGVGASGLNEFGETG 433
            +  G  GGG      G G  G NE G  G
Sbjct: 237 GNQGGGYGGG------GGGYDGYNEGGNFG 260



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 50/197 (25%), Positives = 69/197 (35%), Gaps = 29/197 (14%)

Query: 161 RERWDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQT 220
           +E   AG+ R         G SG  +G G      G       +FG  G       G++ 
Sbjct: 145 QEMQSAGSQRGHG------GGSGNFMGRGGNFGGAGGNFGLGGNFGGRGGYGGGGGGSRG 198

Query: 221 SSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEA 280
           S   G    D G   F  +    GGG   S    +  G  G+G N+ GG G  G      
Sbjct: 199 SYGRG----DGGYNRFGRDGGNYGGGPGYSSRGGYGGGGTGYG-NQGGGYGGGGG----- 248

Query: 281 GFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDS 340
           G+ G+    +          FG G   GG   N+ D G N SG   ++     G   G  
Sbjct: 249 GYDGYNEGGN----------FGGGNYGGGG--NYNDFG-NHSGQQQSNYGPMKGGSFGGR 295

Query: 341 SARNGFENSSGISEDSG 357
           S+ + +    G    SG
Sbjct: 296 SSGSPYGGGYGSGGGSG 312



>gi|51468696|ref|XP_372445.2|   PREDICTED: similar to VsaA -like protein [Homo sapiens]
          Length = 322

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 28/127 (22%), Positives = 51/127 (40%), Gaps = 16/127 (12%)

Query: 52  SPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSG 111
           +PG+ E  ++     G   ++DTP  G   + ++SG +  T          PG  E  + 
Sbjct: 141 TPGDGEMPTQDTPGDGEMPTQDTPGDGEMPTQNTSGHTQDT----------PGDGEMPTQ 190

Query: 112 DSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRS 171
           D+   G   ++DTP  G      + GD +             G+ E  +++    G   +
Sbjct: 191 DTSGDGEMPTQDTPGDGEMPTQDTPGDGEMPTQ------DTPGDGEMPTQDTPGDGEMPT 244

Query: 172 EDSPAVG 178
           +D+P  G
Sbjct: 245 QDTPGDG 251



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 21/89 (23%), Positives = 36/89 (40%), Gaps = 6/89 (6%)

Query: 52  SPGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSG 111
           +PG+ E  ++     G   ++DTP  G   +  + GD +            PG  E  + 
Sbjct: 181 TPGDGEMPTQDTSGDGEMPTQDTPGDGEMPTQDTPGDGEMPTQ------DTPGDGEMPTQ 234

Query: 112 DSQDAGGSKSEDTPPGGFFYGSSSSGDSD 140
           D+   G   ++DTP  G      + GD +
Sbjct: 235 DTPGDGEMPTQDTPGDGEMPTQDTPGDGE 263



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 35/139 (25%), Positives = 58/139 (41%), Gaps = 13/139 (9%)

Query: 53  PGETEDKSRQRQDAGSPKSEDTPAGGFFNSSSSSGDSDR-TKPFFSLG----LGAPGKAE 107
           PG+ E  ++     G   ++DTP  G   + ++SGD +  T+     G       PG  E
Sbjct: 69  PGDGEMPTQDTPGDGEMPTQDTPGDGEMPTQNTSGDGEMPTQDMPGDGEMPTQDTPGDGE 128

Query: 108 ----DKSGDSQDAGGS---KSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGAT-GEDEDK 159
               + SG +QD  G     ++DTP  G      + GD +      S     T G+ E  
Sbjct: 129 MPTQNTSGHTQDTPGDGEMPTQDTPGDGEMPTQDTPGDGEMPTQNTSGHTQDTPGDGEMP 188

Query: 160 SRERWDAGNSRSEDSPAVG 178
           +++    G   ++D+P  G
Sbjct: 189 TQDTSGDGEMPTQDTPGDG 207



>gi|28559039|ref|NP_004765.2|   peroxisome proliferator-activated receptor binding protein [Homo
            sapiens]
          Length = 1581

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 73/334 (21%), Positives = 113/334 (33%), Gaps = 36/334 (10%)

Query: 99   GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
            G G   K   +S    + G  KS+D PP           D++ K P  S           
Sbjct: 985  GPGLDSKPGKRSRTPSNDG--KSKDKPP------KRKKADTEGKSPSHSSSNRPFTPPTS 1036

Query: 159  KSRERWDAGNSRSEDSPAVGTGS-SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG 217
                +      RS+  P V T     + +   KG    G   S S       +SS   + 
Sbjct: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1096

Query: 218  NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVS 277
            + + SS  S S     TS + ++    G S + +S+   S Q   G ++   +  SG   
Sbjct: 1097 HHSHSSSSSSS---ASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153

Query: 278  AEAGFKGFGSDSSSSVEK-------SWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              +     G  S SS  K       S L    L +       +    GS++     +  K
Sbjct: 1154 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA---SPMK 1210

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G     S A++   + SG S  SG             + +    K SS    +G+LS
Sbjct: 1211 PVPGTPPS-SKAKSPISSGSGGSHMSG-------------TSSSSGMKSSSGLGSSGSLS 1256

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
              +  S +     SS   S G   S+ +   G+S
Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 66/307 (21%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            GK+ +S+S G S    SS        ++S + GS G ++ K+   Q  G P S      G
Sbjct: 1112 GKMKSSKSEGSSSSKLSSS-------MYSSQ-GSSGSSQSKNSS-QSGGKPGSSPITKHG 1162

Query: 79   FFNSSSSS-----------------------------GDSDRTKPFFSLGLGAPGKAEDK 109
              + SSS+                             G SD+         G P  ++ K
Sbjct: 1163 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1222

Query: 110  SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            S  S  +GGS    T        SSSSG         S   G++G    K+     + NS
Sbjct: 1223 SPISSGSGGSHMSGT--------SSSSGMKS------SSGLGSSGSLSQKTP---PSSNS 1265

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
             +  S +  +  S +     +  ++ G   S +     T +  K   G  TS  GG   +
Sbjct: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325

Query: 230  DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS 289
            D G            G S NS S+   S     G    G    S    ++    G   DS
Sbjct: 1326 D-GQM----------GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1374

Query: 290  SSSVEKS 296
            S    +S
Sbjct: 1375 SKKTSES 1381



>gi|3319290|gb|AAC39854.1|   thyroid hormone receptor-associated protein complex component TRAP220
            [Homo sapiens]
          Length = 1581

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 73/334 (21%), Positives = 113/334 (33%), Gaps = 36/334 (10%)

Query: 99   GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
            G G   K   +S    + G  KS+D PP           D++ K P  S           
Sbjct: 985  GPGLDSKPGKRSRTPSNDG--KSKDKPP------KRKKADTEGKSPSHSSSNRPFTPPTS 1036

Query: 159  KSRERWDAGNSRSEDSPAVGTGS-SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG 217
                +      RS+  P V T     + +   KG    G   S S       +SS   + 
Sbjct: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1096

Query: 218  NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVS 277
            + + SS  S S     TS + ++    G S + +S+   S Q   G ++   +  SG   
Sbjct: 1097 HHSHSSSSSSS---ASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153

Query: 278  AEAGFKGFGSDSSSSVEK-------SWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              +     G  S SS  K       S L    L +       +    GS++     +  K
Sbjct: 1154 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA---SPMK 1210

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G     S A++   + SG S  SG             + +    K SS    +G+LS
Sbjct: 1211 PVPGTPPS-SKAKSPISSGSGGSHMSG-------------TSSSSGMKSSSGLGSSGSLS 1256

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
              +  S +     SS   S G   S+ +   G+S
Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 66/307 (21%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            GK+ +S+S G S    SS        ++S + GS G ++ K+   Q  G P S      G
Sbjct: 1112 GKMKSSKSEGSSSSKLSSS-------MYSSQ-GSSGSSQSKNSS-QSGGKPGSSPITKHG 1162

Query: 79   FFNSSSSS-----------------------------GDSDRTKPFFSLGLGAPGKAEDK 109
              + SSS+                             G SD+         G P  ++ K
Sbjct: 1163 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1222

Query: 110  SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            S  S  +GGS    T        SSSSG         S   G++G    K+     + NS
Sbjct: 1223 SPISSGSGGSHMSGT--------SSSSGMKS------SSGLGSSGSLSQKTP---PSSNS 1265

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
             +  S +  +  S +     +  ++ G   S +     T +  K   G  TS  GG   +
Sbjct: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325

Query: 230  DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS 289
            D G            G S NS S+   S     G    G    S    ++    G   DS
Sbjct: 1326 D-GQM----------GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1374

Query: 290  SSSVEKS 296
            S    +S
Sbjct: 1375 SKKTSES 1381



>gi|28558772|sp|Q15648|PPRB_HUMAN   Peroxisome proliferator-activated receptor binding protein (PBP)
            (PPAR binding protein) (Thyroid hormone
            receptor-associated protein complex 220 kDa component)
            (Trap220) (Thyroid receptor interacting protein 2)
            (TRIP2) (p53 regulatory protein RB18A) (Vitamin D
            receptor-interacting protein complex component DRIP205)
            (Activator-recruited cofactor 205 kDa component) (ARC205)
          Length = 1581

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 73/334 (21%), Positives = 113/334 (33%), Gaps = 36/334 (10%)

Query: 99   GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
            G G   K   +S    + G  KS+D PP           D++ K P  S           
Sbjct: 985  GPGLDSKPGKRSRTPSNDG--KSKDKPP------KRKKADTEGKSPSHSSSNRPFTPPTS 1036

Query: 159  KSRERWDAGNSRSEDSPAVGTGS-SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG 217
                +      RS+  P V T     + +   KG    G   S S       +SS   + 
Sbjct: 1037 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1096

Query: 218  NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVS 277
            + + SS  S S     TS + ++    G S + +S+   S Q   G ++   +  SG   
Sbjct: 1097 HHSHSSSSSSS---ASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1153

Query: 278  AEAGFKGFGSDSSSSVEK-------SWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              +     G  S SS  K       S L    L +       +    GS++     +  K
Sbjct: 1154 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA---SPMK 1210

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G     S A++   + SG S  SG             + +    K SS    +G+LS
Sbjct: 1211 PVPGTPPS-SKAKSPISSGSGGSHMSG-------------TSSSSGMKSSSGLGSSGSLS 1256

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
              +  S +     SS   S G   S+ +   G+S
Sbjct: 1257 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 66/307 (21%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            GK+ +S+S G S    SS        ++S + GS G ++ K+   Q  G P S      G
Sbjct: 1112 GKMKSSKSEGSSSSKLSSS-------MYSSQ-GSSGSSQSKNSS-QSGGKPGSSPITKHG 1162

Query: 79   FFNSSSSS-----------------------------GDSDRTKPFFSLGLGAPGKAEDK 109
              + SSS+                             G SD+         G P  ++ K
Sbjct: 1163 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1222

Query: 110  SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            S  S  +GGS    T        SSSSG         S   G++G    K+     + NS
Sbjct: 1223 SPISSGSGGSHMSGT--------SSSSGMKS------SSGLGSSGSLSQKTP---PSSNS 1265

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
             +  S +  +  S +     +  ++ G   S +     T +  K   G  TS  GG   +
Sbjct: 1266 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1325

Query: 230  DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS 289
            D G            G S NS S+   S     G    G    S    ++    G   DS
Sbjct: 1326 D-GQM----------GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1374

Query: 290  SSSVEKS 296
            S    +S
Sbjct: 1375 SKKTSES 1381



>gi|9789555|gb|AAF98352.1|   vitamin D receptor-interacting protein complex component DRIP205
            [Homo sapiens]
          Length = 1566

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 73/334 (21%), Positives = 113/334 (33%), Gaps = 36/334 (10%)

Query: 99   GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 158
            G G   K   +S    + G  KS+D PP           D++ K P  S           
Sbjct: 970  GPGLDSKPGKRSRTPSNDG--KSKDKPP------KRKKADTEGKSPSHSSSNRPFTPPTS 1021

Query: 159  KSRERWDAGNSRSEDSPAVGTGS-SGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEG 217
                +      RS+  P V T     + +   KG    G   S S       +SS   + 
Sbjct: 1022 TGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKS 1081

Query: 218  NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVS 277
            + + SS  S S     TS + ++    G S + +S+   S Q   G ++   +  SG   
Sbjct: 1082 HHSHSSSSSSS---ASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKP 1138

Query: 278  AEAGFKGFGSDSSSSVEK-------SWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSK 330
              +     G  S SS  K       S L    L +       +    GS++     +  K
Sbjct: 1139 GSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLA---SPMK 1195

Query: 331  DFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
               G     S A++   + SG S  SG             + +    K SS    +G+LS
Sbjct: 1196 PVPGTPPS-SKAKSPISSGSGGSHMSG-------------TSSSSGMKSSSGLGSSGSLS 1241

Query: 391  PGSDVSDSGGNTWSSDSGSGGGGKSADELGVGAS 424
              +  S +     SS   S G   S+ +   G+S
Sbjct: 1242 QKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1275



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 71/307 (23%), Positives = 104/307 (33%), Gaps = 66/307 (21%)

Query: 19   GKIAASRSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSEDTPAGG 78
            GK+ +S+S G S    SS        ++S + GS G ++ K+   Q  G P S      G
Sbjct: 1097 GKMKSSKSEGSSSSKLSSS-------MYSSQ-GSSGSSQSKNSS-QSGGKPGSSPITKHG 1147

Query: 79   FFNSSSSS-----------------------------GDSDRTKPFFSLGLGAPGKAEDK 109
              + SSS+                             G SD+         G P  ++ K
Sbjct: 1148 LSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAK 1207

Query: 110  SGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNS 169
            S  S  +GGS    T        SSSSG         S   G++G    K+     + NS
Sbjct: 1208 SPISSGSGGSHMSGT--------SSSSGMKS------SSGLGSSGSLSQKTP---PSSNS 1250

Query: 170  RSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSI 229
             +  S +  +  S +     +  ++ G   S +     T +  K   G  TS  GG   +
Sbjct: 1251 CTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPL 1310

Query: 230  DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS 289
            D G            G S NS S+   S     G    G    S    ++    G   DS
Sbjct: 1311 D-GQM----------GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDS 1359

Query: 290  SSSVEKS 296
            S    +S
Sbjct: 1360 SKKTSES 1366



>gi|7959181|dbj|BAA95984.1|   KIAA1460 protein [Homo sapiens]
          Length = 1400

 Score = 36.6 bits (83), Expect = 0.30
 Identities = 50/190 (26%), Positives = 78/190 (41%), Gaps = 49/190 (25%)

Query: 105 KAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERW 164
           + E K+ +  +A GS +  T         +S    DK  P  +     +G  + K   RW
Sbjct: 179 RGERKTDNGTEAWGSSATQT--------FNSGACIDKTSPNGNDTSSVSGWGDPKPALRW 230

Query: 165 DAGNSRS--------EDSPAVGTGSSGL-----------------KLGAGKGD-AAFGFE 198
             G+S+         +DS A G   S                   K G G G  ++ G+ 
Sbjct: 231 --GDSKGSNCQGGWEDDSAATGMVKSNQWGNCKEEKAAWNDSQKNKQGWGDGQKSSQGWS 288

Query: 199 VSDSNSFGDTGISSKTVEGNQTSSSGGSVS-------IDLGDTSFRSENQFVGGGSLN-S 250
           VS S+++G+T  ++   E N+ SSSGGS S        +LG TS      F  G ++N +
Sbjct: 289 VSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNELGKTS-----SFTWGNNINPN 343

Query: 251 ISNLWDSGQE 260
            S+ WD   +
Sbjct: 344 NSSGWDESSK 353



>gi|386854|gb|AAA36153.1|   type II keratin subunit protein
          Length = 493

 Score = 36.2 bits (82), Expect = 0.40
 Identities = 40/157 (25%), Positives = 56/157 (35%), Gaps = 19/157 (12%)

Query: 166 AGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGG 225
           +G      S  V T  + +  G  +G    G+  S  +S+G  G S     G+     GG
Sbjct: 343 SGECAPNVSVTVSTSHTSMSGGGSRGGGGGGYG-SGGSSYGSGGCSY----GSGGGGGGG 397

Query: 226 SVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGF 285
             S   G +S+ S     G G        + SG    G     G G  GS    +G +G 
Sbjct: 398 RGSYGSGGSSYGSGGSSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGS----SGGRGS 453

Query: 286 GSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQS 322
           G  SS           G G + GG     + SG + S
Sbjct: 454 GGGSSGGSSG------GRGSSSGGV----KSSGGSSS 480



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 45/145 (31%), Positives = 53/145 (36%), Gaps = 25/145 (17%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           MSG  S   G  G+GS  SS    S    +G G   GG   ++   GS  S  +G SS  
Sbjct: 361 MSGGGSRGGGGGGYGSGGSS--YGSGGCSYGSGGGGGGGRGSYGSGGS--SYGSGGSSYG 416

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
             G G G  S  +G  +S G    SG                GG    S      G  S 
Sbjct: 417 SGGGGGGHGSYGSG-SSSGGYRGGSG----------------GGGGGSSGGRGSGGGSSG 459

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSA 416
           GS    SGG   SS      GG S+
Sbjct: 460 GS----SGGRGSSSGGVKSSGGSSS 480



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 38/146 (26%), Positives = 52/146 (35%), Gaps = 21/146 (14%)

Query: 212 SKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNG 271
           S TV  + TS SGG              ++  GGG   S  + + SG   +G    GG G
Sbjct: 351 SVTVSTSHTSMSGGG-------------SRGGGGGGYGSGGSSYGSGGCSYGSGGGGGGG 397

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGN---- 327
                S  + +   GS   S         +G G + GG        G   SG  G+    
Sbjct: 398 RGSYGSGGSSYGSGGSSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGS 457

Query: 328 SSKDFDGNGVGDSSARNGFENSSGIS 353
           S     G G    S+  G ++S G S
Sbjct: 458 SGGSSGGRG----SSSGGVKSSGGSS 479



>gi|9663124|emb|CAC01124.1|   ILF3 [Homo sapiens]
          Length = 441

 Score = 36.2 bits (82), Expect = 0.40
 Identities = 68/271 (25%), Positives = 93/271 (34%), Gaps = 38/271 (14%)

Query: 178 GTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVEGNQTSSSGGSVSIDLGD 233
           G G S  G   G G G A  G  ++    +G  G   +S T   +Q  S+GG        
Sbjct: 190 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGG-------- 241

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-FGSDSSSS 292
               S N   GGG           G  G+G    G N  S      AG K   G     S
Sbjct: 242 ---HSGNASGGGGG-------GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 291

Query: 293 VEKSWLFEFGLG-ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
                   +G G ++  G + ++  S  +  G      K ++ +G G  S  N + NS G
Sbjct: 292 --------YGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYN-HGQGSYSYSNSY-NSPG 341

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
               S     S   +     R+GGN   S       + +PGS     GG+   S      
Sbjct: 342 GGRGSDYNYESKFNYSGSGGRSGGNSYGSG----GASYNPGSHGGYGGGSGGGSSYQGKQ 397

Query: 412 GGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           GG S        SG N  G      S +G +
Sbjct: 398 GGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 428



>gi|8017378|emb|CAB92132.1|   hypothetical protein [Homo sapiens]
          Length = 554

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 47/179 (26%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 731 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCP-----------SGL 779
           CK   C   N   C     G   K C++ +    G +   C+H C            SG 
Sbjct: 69  CKFGECVGPNKCRCFPGYTG---KTCSQ-DVNECGMKPRPCQHRCVNTHGSYKCFCLSGH 124

Query: 780 VFKYNVKACNSSCRSLSERDRSC-DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND 838
           +   +    NS   ++     SC D E+ P   C CP +      G  +  +  DC   D
Sbjct: 125 MLMPDATCVNSRTCAMINCQYSCEDTEEGPQ--CLCPSS------GLRLAPNGRDCLDID 176

Query: 839 EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
           E    GK+I   + +CV   G   C+  I   LQ  SG     DC D       + TCS
Sbjct: 177 ECAS-GKVICPYNRRCVNTFGSYYCKCHIGFELQYISG---RYDCIDINECTMDSHTCS 231



>gi|13124888|ref|NP_056322.2|   epidermal growth factor-like protein 6 precursor [Homo sapiens]
 gi|24047224|gb|AAH38587.1|   Epidermal growth factor-like protein 6, precursor [Homo sapiens]
          Length = 553

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 47/179 (26%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 731 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCP-----------SGL 779
           CK   C   N   C     G   K C++ +    G +   C+H C            SG 
Sbjct: 69  CKFGECVGPNKCRCFPGYTG---KTCSQ-DVNECGMKPRPCQHRCVNTHGSYKCFCLSGH 124

Query: 780 VFKYNVKACNSSCRSLSERDRSC-DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND 838
           +   +    NS   ++     SC D E+ P   C CP +      G  +  +  DC   D
Sbjct: 125 MLMPDATCVNSRTCAMINCQYSCEDTEEGPQ--CLCPSS------GLRLAPNGRDCLDID 176

Query: 839 EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
           E    GK+I   + +CV   G   C+  I   LQ  SG     DC D       + TCS
Sbjct: 177 ECAS-GKVICPYNRRCVNTFGSYYCKCHIGFELQYISG---RYDCIDINECTMDSHTCS 231



>gi|37181791|gb|AAQ88699.1|   EGFL6 [Homo sapiens]
          Length = 338

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 47/179 (26%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 731 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCP-----------SGL 779
           CK   C   N   C     G   K C++ +    G +   C+H C            SG 
Sbjct: 69  CKFGECVGPNKCRCFPGYTG---KTCSQ-DVNECGMKPRPCQHRCVNTHGSYKCFCLSGH 124

Query: 780 VFKYNVKACNSSCRSLSERDRSC-DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND 838
           +   +    NS   ++     SC D E+ P   C CP +      G  +  +  DC   D
Sbjct: 125 MLMPDATCVNSRTCAMINCQYSCEDTEEGPQ--CLCPSS------GLRLAPNGRDCLDID 176

Query: 839 EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
           E    GK+I   + +CV   G   C+  I   LQ  SG     DC D       + TCS
Sbjct: 177 ECAS-GKVICPYNRRCVNTFGSYYCKCHIGFELQYISG---RYDCIDINECTMDSHTCS 231



>gi|22761159|dbj|BAC11477.1|   unnamed protein product [Homo sapiens]
          Length = 553

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 47/179 (26%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 731 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCP-----------SGL 779
           CK   C   N   C     G   K C++ +    G +   C+H C            SG 
Sbjct: 69  CKFGECVGPNKCRCFPGYTG---KTCSQ-DVNECGMKPRPCQHRCVNTHGSYKCFCLSGH 124

Query: 780 VFKYNVKACNSSCRSLSERDRSC-DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND 838
           +   +    NS   ++     SC D E+ P   C CP +      G  +  +  DC   D
Sbjct: 125 MLMPDATCVNSRTCAMINCQYSCEDTEEGPQ--CLCPSS------GLRLAPNGRDCLDID 176

Query: 839 EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
           E    GK+I   + +CV   G   C+  I   LQ  SG     DC D       + TCS
Sbjct: 177 ECAS-GKVICPYNRRCVNTFGSYYCKCHIGFELQYISG---RYDCIDINECTMDSHTCS 231



>gi|57209317|emb|CAI40809.1|   proprotein convertase subtilisin\/kexin type 5 [Homo sapiens]
 gi|57209231|emb|CAI40675.1|   proprotein convertase subtilisin\/kexin type 5 [Homo sapiens]
 gi|57208981|emb|CAI41234.1|   proprotein convertase subtilisin\/kexin type 5 [Homo sapiens]
          Length = 1560

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 27/110 (24%)

Query: 726  PYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNV 785
            P H++C +  C+   + DC         + C E    +     GLC   CP+G  ++   
Sbjct: 1070 PCHKDCLE--CSGPKADDC---------ELCLESSWVLYD---GLCLEECPAGTYYEKET 1115

Query: 786  KA---CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 832
            K    C+ SC + S    +C          TC   +  N  G+C+   +C
Sbjct: 1116 KECRDCHKSCLTCSS-SGTC---------TTCQKGLIMNPRGSCMANEKC 1155



>gi|57209230|emb|CAI40674.1|   OTTHUMP00000063526 [Homo sapiens]
          Length = 612

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 27/110 (24%)

Query: 726 PYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNV 785
           P H++C +  C+   + DC         + C E    +     GLC   CP+G  ++   
Sbjct: 122 PCHKDCLE--CSGPKADDC---------ELCLESSWVLYD---GLCLEECPAGTYYEKET 167

Query: 786 KA---CNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQC 832
           K    C+ SC + S    +C          TC   +  N  G+C+   +C
Sbjct: 168 KECRDCHKSCLTCSS-SGTC---------TTCQKGLIMNPRGSCMANEKC 207



>gi|11935049|gb|AAG41947.1|   keratin 1 [Homo sapiens]
 gi|17318569|ref|NP_006112.2|   keratin 1 [Homo sapiens]
 gi|39794653|gb|AAH63697.1|   Keratin 1 [Homo sapiens]
          Length = 644

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 41/153 (26%), Positives = 59/153 (38%), Gaps = 22/153 (14%)

Query: 215 VEGNQTSSSGG-----SVSIDLGDTSFRSE-NQFVGGGSLNSISNLWDSGQEGFGINEIG 268
           +EG ++  SG      SVS+    T+     ++  GGG   S  + + SG   +G    G
Sbjct: 486 LEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGG 545

Query: 269 GNGM----SGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD 324
           G G     SG  S  +G   +GS        S    +G G + GG        G   SG 
Sbjct: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGS----YGSGSSSGGYRGGSGGGGGGSSGG 601

Query: 325 NGN----SSKDFDGNGVGDSSARNGFENSSGIS 353
            G+    S     G G    S+  G ++S G S
Sbjct: 602 RGSGGGSSGGSIGGRG----SSSGGVKSSGGSS 630



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 14/118 (11%)

Query: 182 SGLKLGAGKGDAAFGF--------EVSDSNSFGDTGISSKTVEGNQTSSSGGSVS----I 229
           SG + G G    + G           S   S G  G  S    G  +  +GG       +
Sbjct: 9   SGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLV 68

Query: 230 DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
           +LG +   S +   GGG  +     +  G  GFG    GG G  G      GF GFGS
Sbjct: 69  NLGGSKSISISVARGGGRGSGFGGGYGGG--GFGGGGFGGGGFGGGGIGGGGFGGFGS 124



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 39/162 (24%), Positives = 51/162 (31%), Gaps = 36/162 (22%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           MS   S+ +G++  G  SS S               G   +  R + S+     G   + 
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSA--------------GIINYQRRTTSSSTRRSGGGGGRF 46

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
               G G S    G     G    S V LG S    + ++R GG                
Sbjct: 47  SSCGGGGGSFGAGG-----GFGSRSLVNLGGSKSISISVARGGGR--------------- 86

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETG 433
           GS      G       G GGGG      G+G  G   FG  G
Sbjct: 87  GSGFGGGYGGGGFGGGGFGGGGFGGG--GIGGGGFGGFGSGG 126



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 39/146 (26%), Positives = 48/146 (32%), Gaps = 27/146 (18%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           +SG  S   G  G+GS  SS         +G     GG  +     G    G  G+    
Sbjct: 512 ISGGGSRGGGGGGYGSGGSS---------YG----SGGGSYGSGGGGGGGRGSYGSGGSS 558

Query: 332 F-DGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
           +  G G   S    G   S G    SG   G S          GG    SS    +G  S
Sbjct: 559 YGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGS----------GGGGGGSSGGRGSGGGS 608

Query: 391 PGSDVSDSGGNTWSSDSGSGGGGKSA 416
            G  +   GG   SS      GG S+
Sbjct: 609 SGGSI---GGRGSSSGGVKSSGGSSS 631



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 39/134 (29%), Positives = 48/134 (35%), Gaps = 14/134 (10%)

Query: 160 SRERWDAGNSRSEDSPAV------GTGSSGLKLGAGKGDAAFGFEVSDSNSFG-DTGISS 212
           SR  + +G   S  S  +       T SS  + G G G   F        SFG   G  S
Sbjct: 7   SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGG--RFSSCGGGGGSFGAGGGFGS 64

Query: 213 KTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGM 272
           +++      + GGS SI +            GGG           G  GFG   IGG G 
Sbjct: 65  RSLV-----NLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGF 119

Query: 273 SGSVSAEAGFKGFG 286
            G  S   GF G G
Sbjct: 120 GGFGSGGGGFGGGG 133



>gi|9055270|ref|NP_061027.1|   low density lipoprotein-related protein 1B [Homo sapiens]
 gi|7861733|gb|AAF70379.1|   low density lipoprotein receptor related protein-deleted in tumor
            [Homo sapiens]
          Length = 4599

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 58/259 (22%), Positives = 90/259 (34%), Gaps = 47/259 (18%)

Query: 684  CPKG--------NPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYT 735
            CP+G        N  S +    +   E     +L+  G L  CH    P    E C+   
Sbjct: 4196 CPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLR-CH--CWPSYSGERCEVNH 4252

Query: 736  CT--CENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSG---LVFKYNVKACNS 790
            C+  C+N   C+ ++LG    +CA   T     +T +CE  C +G   +V   N   C+ 
Sbjct: 4253 CSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKT-VCEDFCQNGGTCIVTAGNQPYCHC 4311

Query: 791  S------------CRSLSERDRSCDVEDVPVDGCTCP----------DAMYQNNEGNCVL 828
                         C        SC + D     C CP          D   + + G+C++
Sbjct: 4312 QPEYTGDRCQYYVCHHYCVNSESCTIGDDGSXECVCPTRYEGPKCEVDKCVRCHGGHCII 4371

Query: 829  -KSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILL---CQIPIDLTLQNCSGGAEYVDCS 884
             K   D + N    +      + D  C       L     +P+ L   N SG      C 
Sbjct: 4372 NKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSG----TQCE 4427

Query: 885  DPKAQRRTNRTCSTRNIPV 903
             P  +   +   STR+I +
Sbjct: 4428 RPAPKSSKSDHISTRSIAI 4446



>gi|6752658|gb|AAF27812.1|   epidermal growth factor repeat containing protein [Homo sapiens]
          Length = 553

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 47/179 (26%), Positives = 65/179 (36%), Gaps = 28/179 (15%)

Query: 731 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCP-----------SGL 779
           CK   C   N   C     G   K C++ +    G +   C+H C            SG 
Sbjct: 69  CKFGECVGPNKCRCFPGYTG---KTCSQ-DVNECGMKPRPCQHRCVNTHGSYKCFCLSGH 124

Query: 780 VFKYNVKACNSSCRSLSERDRSC-DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND 838
           +   +    NS   ++     SC D E+ P   C CP +      G  +  +  DC   D
Sbjct: 125 MLMPDATCVNSRTCAMINCQYSCEDTEEGPQ--CLCPSS------GLRLAPNGRDCLDID 176

Query: 839 EVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCS 897
           E    GK+I   + +CV   G   C+  I   LQ  SG     DC D       + TCS
Sbjct: 177 ECAS-GKVICPYNRRCVNTFGSYYCKCHIGFELQYISG---RYDCIDINECTMDSHTCS 231



>gi|1346343|sp|P04264|K2C1_HUMAN   Keratin, type II cytoskeletal 1 (Cytokeratin 1) (K1) (CK 1) (67 kDa
           cytokeratin) (Hair alpha protein)
 gi|186772|gb|AAB47721.1|   keratin 1
 gi|7331218|gb|AAF60327.1|   keratin 1 [Homo sapiens]
          Length = 644

 Score = 35.8 bits (81), Expect = 0.52
 Identities = 41/153 (26%), Positives = 59/153 (38%), Gaps = 22/153 (14%)

Query: 215 VEGNQTSSSGG-----SVSIDLGDTSFRSE-NQFVGGGSLNSISNLWDSGQEGFGINEIG 268
           +EG ++  SG      SVS+    T+     ++  GGG   S  + + SG   +G    G
Sbjct: 486 LEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGG 545

Query: 269 GNGM----SGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD 324
           G G     SG  S  +G   +GS        S    +G G + GG        G   SG 
Sbjct: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGS----YGSGSSSGGYRGGSGGGGGGSSGG 601

Query: 325 NGN----SSKDFDGNGVGDSSARNGFENSSGIS 353
            G+    S     G G    S+  G ++S G S
Sbjct: 602 RGSGGGSSGGSIGGRG----SSSGGVKSSGGSS 630



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 14/118 (11%)

Query: 182 SGLKLGAGKGDAAFGF--------EVSDSNSFGDTGISSKTVEGNQTSSSGGSVS----I 229
           SG + G G    + G           S   S G  G  S    G  +  +GG       +
Sbjct: 9   SGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLV 68

Query: 230 DLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS 287
           +LG +   S +   GGG  +     +  G  GFG    GG G  G      GF GFGS
Sbjct: 69  NLGGSKSISISVARGGGRGSGFGGGYGGG--GFGGGGFGGGGFGGGGIGGGGFGGFGS 124



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 39/162 (24%), Positives = 51/162 (31%), Gaps = 36/162 (22%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           MS   S+ +G++  G  SS S               G   +  R + S+     G   + 
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSA--------------GIINYQRRTTSSSTRRSGGGGGRF 46

Query: 332 FDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSP 391
               G G S    G     G    S V LG S    + ++R GG                
Sbjct: 47  SSCGGGGGSFGAGG-----GFGSRSLVNLGGSKSISISVARGGGR--------------- 86

Query: 392 GSDVSDSGGNTWSSDSGSGGGGKSADELGVGASGLNEFGETG 433
           GS      G       G GGGG      G+G  G   FG  G
Sbjct: 87  GSGFGGGYGGGGFGGGGFGGGGFGGG--GIGGGGFGGFGSGG 126



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 39/146 (26%), Positives = 48/146 (32%), Gaps = 27/146 (18%)

Query: 272 MSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKD 331
           +SG  S   G  G+GS  SS         +G     GG  +     G    G  G+    
Sbjct: 512 ISGGGSRGGGGGGYGSGGSS---------YG----SGGGSYGSGGGGGGGRGSYGSGGSS 558

Query: 332 F-DGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS 390
           +  G G   S    G   S G    SG   G S          GG    SS    +G  S
Sbjct: 559 YGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGS----------GGGGGGSSGGRGSGGGS 608

Query: 391 PGSDVSDSGGNTWSSDSGSGGGGKSA 416
            G  +   GG   SS      GG S+
Sbjct: 609 SGGSI---GGRGSSSGGVKSSGGSSS 631



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 39/134 (29%), Positives = 48/134 (35%), Gaps = 14/134 (10%)

Query: 160 SRERWDAGNSRSEDSPAV------GTGSSGLKLGAGKGDAAFGFEVSDSNSFG-DTGISS 212
           SR  + +G   S  S  +       T SS  + G G G   F        SFG   G  S
Sbjct: 7   SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGG--RFSSCGGGGGSFGAGGGFGS 64

Query: 213 KTVEGNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGM 272
           +++      + GGS SI +            GGG           G  GFG   IGG G 
Sbjct: 65  RSLV-----NLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGF 119

Query: 273 SGSVSAEAGFKGFG 286
            G  S   GF G G
Sbjct: 120 GGFGSGGGGFGGGG 133



>gi|15079614|gb|AAH11625.1|   Zinc finger protein 503 [Homo sapiens]
 gi|24432032|ref|NP_116161.2|   zinc finger protein 503 [Homo sapiens]
          Length = 646

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 47/171 (27%), Positives = 62/171 (36%), Gaps = 35/171 (20%)

Query: 269 GNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 328
           G G  G+    AG K    D+ S   K  L + G+ +      ++   S   + G  G  
Sbjct: 141 GGGAGGAGGGAAGDK----DTKSGPLK--LSDIGVEDKSSFKPYSKPGSDKKEPGGGGGG 194

Query: 329 SKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGN 388
                G G G SS ++GF   S   +                 RTG      S    A  
Sbjct: 195 GGGGGGGGGGVSSEKSGFRVPSATCQPF-------------TPRTG------SPSSSASA 235

Query: 389 LSPGSDVSDSG----GNTWSSDSGSGGGGKSADELGVGASGLNEFGETGLS 435
            SPG  +S +G    G     D+  GGGGK       GAS   E G TGL+
Sbjct: 236 CSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTG----GASA--EGGPTGLA 280



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 28/102 (27%), Positives = 34/102 (33%), Gaps = 25/102 (24%)

Query: 348 NSSGISEDSGVILGSSDQHE--VELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSS 405
           N  G     G   G  D     ++LS  G   K S  P       PGSD  + GG     
Sbjct: 140 NGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYS----KPGSDKKEPGGGGGGG 195

Query: 406 DSGSGGGGKSADELGVGASGLNEFGETGLSGSEKGSHIPEAT 447
             G GGGG                   G+S  + G  +P AT
Sbjct: 196 GGGGGGGG-------------------GVSSEKSGFRVPSAT 218



>gi|30582787|gb|AAP35620.1|   ring finger protein 10 [Homo sapiens]
 gi|34452681|ref|NP_055683.3|   ring finger protein 10 [Homo sapiens]
 gi|16741642|gb|AAH16622.1|   Ring finger protein 10 [Homo sapiens]
 gi|5931614|dbj|BAA84708.1|   RIE2 sid2705 [Homo sapiens]
 gi|20521864|dbj|BAA13392.2|   Contains C3HC4 type zinc finger signature [Homo sapiens]
          Length = 811

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 11/154 (7%)

Query: 25  RSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE-----DTPAGGF 79
           ++ G +  S+SSG    ++P  S   G  GE++ KS  +  +GS +         P    
Sbjct: 17  KNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYPKNES 76

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSE--DTPPGGFFYGSSSSG 137
           FN+ S    S ++K F  +     G    K   S   GG + E  +     F     S  
Sbjct: 77  FNNQSRRSSSQKSKTFNKMP-PQRGGGSSKLFSSSFNGGRRDEVAEAQRAEFSPAQFSGP 135

Query: 138 DSDKKKPLFSFEF---GATGEDEDKSRERWDAGN 168
                  L +F F   G TG  E      W   N
Sbjct: 136 KKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRN 169



>gi|225922|prf||1403304A   von Willebrand factor
          Length = 177

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 18/52 (34%), Positives = 25/52 (48%)

Query: 940 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 991
           G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+
Sbjct: 125 GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQ 176



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
           V +    F  T GLCG++N  AEDDFM+ +
Sbjct: 148 VLLSDRYFNKTCGLCGNFNIFAEDDFMTQE 177



>gi|45594508|ref|NP_996669.1|   similar to Hypothetical protein CBG21647 [Homo sapiens]
          Length = 508

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 68/336 (20%), Positives = 120/336 (35%), Gaps = 42/336 (12%)

Query: 104 GKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRER 163
           G   +  G  Q   GS    T       GS  SG    +    S +   TG  +  +   
Sbjct: 38  GSVRNGKGSIQHGTGSIQSGTRKVQHGKGSIQSGMGSVQSGTGSIQ-NVTGSIQSGTGNV 96

Query: 164 WDAGNSRSEDSPAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSS 223
                S    + ++ +G+  ++ G G      G   S  +  G+    + +++    S  
Sbjct: 97  QHGTGSIKNVTGSIQSGTGNVQHGTGSIQNVTG---SIQSGTGNVQHGTGSIQNVTGSIQ 153

Query: 224 GGSVSIDLGDTSFRSENQFVGGGSLN------SISNLWDSGQEGFGINEIGGNGM---SG 274
            G+ ++  G  S ++    +  G+ N      SI N+  S Q G G  + G   +   +G
Sbjct: 154 SGTGNVQHGTGSIKNVTGSIQSGTGNVQHGTGSIQNVTGSIQHGTGSIQSGTRNVQHGTG 213

Query: 275 SV-----SAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNSS 329
           S+     S ++G +     + S    +   + G G  + G       +GS QSG  G+  
Sbjct: 214 SIQHVTGSIQSGTRNVQHGTGSIQHGTGSIQHGTGSIQSGTRNVQHGTGSIQSG-MGSVQ 272

Query: 330 KDFDGNGVGDSSARNGFENSSGISEDSGVI--LGSSDQHEVELSRTGGNRKRSSDPDEAG 387
           +   G G   S  RN    +  +   +G I  +  S QH                    G
Sbjct: 273 R---GTGSIQSGTRNVQRGTGSVQHGTGSIQNVTGSIQHGT------------------G 311

Query: 388 NLSPGSDVSDSGGNTWSSDSGSGGGGKSADELGVGA 423
           ++ PG+     G  +    +GS   GK + + G G+
Sbjct: 312 SVQPGAGSVQCGAGSVQRGTGSVQRGKGSIQRGTGS 347



>gi|24234750|ref|NP_036350.2|   interleukin enhancer binding factor 3 isoform a [Homo sapiens]
          Length = 894

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 68/271 (25%), Positives = 93/271 (34%), Gaps = 38/271 (14%)

Query: 178 GTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVEGNQTSSSGGSVSIDLGD 233
           G G S  G   G G G A  G  ++    +G  G   +S T   +Q  S+GG        
Sbjct: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGG-------- 694

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-FGSDSSSS 292
               S N   GGG           G  G+G    G N  S      AG K   G     S
Sbjct: 695 ---HSGNASGGGGG-------GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 744

Query: 293 VEKSWLFEFGLG-ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
                   +G G ++  G + ++  S  +  G      K ++ +G G  S  N + NS G
Sbjct: 745 --------YGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYN-HGQGSYSYSNSY-NSPG 794

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
               S     S   +     R+GGN   S       + +PGS     GG+   S      
Sbjct: 795 GGGGSDYNYESKFNYSGSGGRSGGNSYGSG----GASYNPGSHGGYGGGSGGGSSYQGKQ 850

Query: 412 GGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           GG S        SG N  G      S +G +
Sbjct: 851 GGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 881



>gi|21619487|gb|AAH31596.1|   Ring finger protein 10 [Homo sapiens]
          Length = 811

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 38/154 (24%), Positives = 56/154 (36%), Gaps = 11/154 (7%)

Query: 25  RSGGFSYGSSSSGDLDRKKPLFSLEFGSPGETEDKSRQRQDAGSPKSE-----DTPAGGF 79
           ++ G +  S+SSG    ++P  S   G  GE++ KS  +  +GS +         P    
Sbjct: 17  KNSGSNSSSASSGSSKGQQPPRSASAGPAGESKPKSDGKNSSGSKRYNRKRELSYPKNES 76

Query: 80  FNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSE--DTPPGGFFYGSSSSG 137
           FN+ S    S ++K F  +     G    K   S   GG + E  +     F     S  
Sbjct: 77  FNNQSRRSSSQKSKTFNKMP-PQRGGGSSKLFSSSFNGGRRDEVAEAQRAEFSPAQFSGP 135

Query: 138 DSDKKKPLFSFEF---GATGEDEDKSRERWDAGN 168
                  L +F F   G TG  E      W   N
Sbjct: 136 KKINLNHLLNFTFEPRGQTGHFEGSGHGSWGKRN 169



>gi|5762315|gb|AAD51099.1|   nuclear factor associated with dsRNA NFAR-2 [Homo sapiens]
 gi|20138587|sp|Q12906|ILF3_HUMAN   Interleukin enhancer-binding factor 3 (Nuclear factor of activated
           T cells-90) (NF-AT-90) (Double-stranded RNA-binding
           protein 76) (DRBP76) (Translational control protein 80)
           (TCP80) (Nuclear factor associated with dsRNA) (NFAR)
           (M-phase phosphoprotein 4) (MPP4)
          Length = 894

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 68/271 (25%), Positives = 93/271 (34%), Gaps = 38/271 (14%)

Query: 178 GTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVEGNQTSSSGGSVSIDLGD 233
           G G S  G   G G G A  G  ++    +G  G   +S T   +Q  S+GG        
Sbjct: 643 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGG-------- 694

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-FGSDSSSS 292
               S N   GGG           G  G+G    G N  S      AG K   G     S
Sbjct: 695 ---HSGNASGGGGG-------GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 744

Query: 293 VEKSWLFEFGLG-ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
                   +G G ++  G + ++  S  +  G      K ++ +G G  S  N + NS G
Sbjct: 745 --------YGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYN-HGQGSYSYSNSY-NSPG 794

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
               S     S   +     R+GGN   S       + +PGS     GG+   S      
Sbjct: 795 GGGGSDYNYESKFNYSGSGGRSGGNSYGSG----GASYNPGSHGGYGGGSGGGSSYQGKQ 850

Query: 412 GGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           GG S        SG N  G      S +G +
Sbjct: 851 GGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 881



>gi|11125762|gb|AAC51260.2|   matrilin-2 precursor [Homo sapiens]
 gi|14549163|sp|O00339|MTN2_HUMAN   Matrilin-2 precursor
          Length = 956

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 23/164 (14%)

Query: 687 GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLC 746
           G    C+++E+  +   H G  LD +G   +C  + +       C++     E+S  C C
Sbjct: 412 GCEHECVNMEESYYCRCHRGYTLDPNG--KTCSRVDHCAQQDHGCEQLCLNTEDSFVCQC 469

Query: 747 T---ILGNYVKACAEKETYIVGWRTGLCEHS-----------CPSGLVFKYNVKACNSSC 792
           +   ++   +K C+  +  ++      CE+S           CP G V + + K C +  
Sbjct: 470 SEGFLINEDLKTCSRVDYCLLSDHG--CEYSCVNMDRSFACQCPEGHVLRSDGKTC-AKL 526

Query: 793 RSLSERDRSCDVEDVPVDG---CTCPDAMYQNNEG-NCVLKSQC 832
            S +  D  C+   V  +    C C +      +G  C  K  C
Sbjct: 527 DSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVC 570



>gi|1200090|emb|CAA29985.1|   von Willebrand factor [Homo sapiens]
          Length = 178

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 18/52 (34%), Positives = 25/52 (48%)

Query: 940 GLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 991
           G Y +     G +   D +    V+L   +  K CGLCGN N   +DDF T+
Sbjct: 125 GYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQ 176



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 636 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ 665
           V +    F  T GLCG++N  AEDDFM+ +
Sbjct: 148 VLLSDRYFNKTCGLCGNFNIFAEDDFMTQE 177



>gi|9081981|gb|AAF82685.1|   dsRNA binding protein NFAR-2/MPP4 [Homo sapiens]
          Length = 709

 Score = 35.4 bits (80), Expect = 0.68
 Identities = 66/273 (24%), Positives = 95/273 (34%), Gaps = 40/273 (14%)

Query: 178 GTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVEGNQTSSSGGSVSIDLGD 233
           G G S  G   G G G A  G  ++    +G  G   +S T   +Q  S+GG        
Sbjct: 456 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGG-------- 507

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-FGSDSSSS 292
               S N   GGG           G  G+G    G N  S      AG K   G     S
Sbjct: 508 ---HSGNASGGGGG-------GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 557

Query: 293 VEKSWLFEFGLG-ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
                   +G G ++  G + ++  S  +  G      K ++ +G G  S  N + +  G
Sbjct: 558 --------YGSGYQSHQGQQQSYNQSPYSNYGPPQGKQKGYN-HGQGSYSYSNSYNSPGG 608

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLS--PGSDVSDSGGNTWSSDSGS 409
                G   GS   +E + + +G   +   +   +G  S  PGS     GG+   S    
Sbjct: 609 -----GGGSGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGGGSGGGSSYQG 663

Query: 410 GGGGKSADELGVGASGLNEFGETGLSGSEKGSH 442
             GG S        SG N  G      S +G +
Sbjct: 664 KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 696



>gi|33413425|ref|NP_061869.2|   trinucleotide repeat containing 6C [Homo sapiens]
          Length = 1690

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 77/349 (22%), Positives = 110/349 (31%), Gaps = 56/349 (16%)

Query: 71  SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFF 130
           S   PA G  NS  S G+ D      S        A  K G    +GG+  +  PP G  
Sbjct: 252 SPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG----SGGNAWDSGPPAG-- 305

Query: 131 YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
            G  + G       + +   GA G              SRS  +   G            
Sbjct: 306 PGILAWGRGSGNNGVGNIHSGAWGHP------------SRSTSNGVNGEW---------- 343

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTVEG-NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLN 249
           G        SD N  G TG  S +V   N T   GG             E+      + +
Sbjct: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGG-------------EHMNSWAKAAS 390

Query: 250 SISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS-----SSSVEKSWLFEFGLG 304
           S +   +   +G G +  G  G  G+       KG           + ++   L   G G
Sbjct: 391 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 450

Query: 305 ET--KGGAEFNFRDS-GSNQSGDNGNSSKDFDGNGVGDSSARN--GFENSSGISEDSGVI 359
           +T  K    + F +S  S +  DNG  +         +S  +N     NS+  S  SG +
Sbjct: 451 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV 510

Query: 360 LGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----GGNTWS 404
                           N K  S P   G+    + VS +     G+ WS
Sbjct: 511 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWS 559



>gi|56789238|gb|AAH88362.1|   DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Homo sapiens]
 gi|13518015|ref|NP_077726.1|   DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Homo sapiens]
 gi|9507237|ref|NP_061912.1|   DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Homo sapiens]
 gi|8102021|gb|AAF72705.1|   VASA protein [Homo sapiens]
 gi|20138033|sp|Q9NQI0|DDX4_HUMAN   DEAD-box protein 4 (VASA homolog)
          Length = 724

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 51/195 (26%), Positives = 70/195 (35%), Gaps = 57/195 (29%)

Query: 309 GAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENS------------------- 349
           G  F  RD+G     DN ++   F   GVG S    GF NS                   
Sbjct: 62  GRNFGNRDAGECNKRDNTSTMGGF---GVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCE 118

Query: 350 ------SGISEDSGVILGSSDQHEVELSRTG-------------GNRKRSSDPDEAGNLS 390
                  G S+  G   G++ +      R G             G+     DPDE    +
Sbjct: 119 DNPTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRT 178

Query: 391 PG------SDVSDSG-GNTWSSDSGSG---GGGKSADELGVGASGLN------EFGETGL 434
            G        +S +G G+T  S SGSG   GG K  +E  +  SG N      E GE+  
Sbjct: 179 GGLFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSD 238

Query: 435 SGSEKGSHIPEATPK 449
           +   K ++IP   P+
Sbjct: 239 TQGPKVTYIPPPPPE 253



>gi|17318572|ref|NP_476429.1|   keratin 3 [Homo sapiens]
 gi|88053|pir||A29666   keratin, 65K type II cytoskeletal - human
          Length = 629

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 39/118 (33%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 176 AVGTGSSGLKLGA---GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSS----SGGSVS 228
           AV +GSS +   A   G G  A+GF  S +  FG   + +  + GN++ S    +GGS +
Sbjct: 21  AVVSGSSRMSCVAHSGGAGGGAYGFR-SGAGGFGSRSLYN--LGGNKSISISVAAGGSRA 77

Query: 229 IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG 286
              G    RS   F GG      S        GFG    GG GM G      GF G G
Sbjct: 78  GGFGGG--RSSCAFAGGYGGGFGSGYGGGFGGGFG----GGRGMGGGFGGAGGFGGAG 129



>gi|52545795|emb|CAH56330.1|   hypothetical protein [Homo sapiens]
          Length = 461

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 7/65 (10%)

Query: 552 WRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPFQDSEC-----VSGCTCPEDKIQI 606
           WR  +  +C    CP   +Y+ CGPSNP+ C          C        C CPE  + +
Sbjct: 12  WRGRTGHMCPFT-CPADKVYQPCGPSNPSYCYGNDSATSGLCRRRPHHRSCFCPEG-MTL 69

Query: 607 FNASS 611
           F+ S+
Sbjct: 70  FSTSA 74



>gi|12746296|gb|AAK07425.1|   110 kDa NFAR protein [Homo sapiens]
          Length = 894

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 48/203 (23%), Positives = 73/203 (35%), Gaps = 39/203 (19%)

Query: 269 GNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 328
           G G  G++      +GFG  +      +     G G    G   N   +G +Q   NG  
Sbjct: 641 GRGRGGTIRGRGRGRGFGGANHGGYMNA-----GAGYGSYGYGGNSATAGYSQFYSNGGH 695

Query: 329 SKDFDGNGVGDSSARNGFEN-SSGISEDSGVILGSSDQHEVELSRTGGNRKRS------- 380
           S +  G G G     +G+ +   G + +S V      +H  +    GG +K S       
Sbjct: 696 SGNASGGGGGGGGGSSGYGSYYQGDNYNSPV----PPKHAGKKQPHGGQQKPSYGSGYQS 751

Query: 381 -SDPDEAGNLSPGSDVS-----------DSGGNTWSSDSGSGGGGKSAD---------EL 419
                ++ N SP S+               G  ++S+   S GGG+ +D           
Sbjct: 752 HQGQQQSYNQSPYSNYGPPQGKQKGYNHGQGSYSYSNSYNSPGGGRGSDYNYESKFNYSG 811

Query: 420 GVGASGLNEFGETGLSGSEKGSH 442
             G SG N +G  G S    GSH
Sbjct: 812 SEGRSGGNSYGSGGAS-YNPGSH 833



>gi|34041|emb|CAA28991.1|   keratin type II (AA1-215) [Homo sapiens]
          Length = 215

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 39/118 (33%), Positives = 50/118 (42%), Gaps = 16/118 (13%)

Query: 176 AVGTGSSGLKLGA---GKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSS----SGGSVS 228
           AV +GSS +   A   G G  A+GF  S +  FG   + +  + GN++ S    +GGS +
Sbjct: 21  AVVSGSSRMSCVAHSGGAGGGAYGFR-SGAGGFGSRSLYN--LGGNKSISISVAAGGSRA 77

Query: 229 IDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFG 286
              G    RS   F GG      S        GFG    GG GM G      GF G G
Sbjct: 78  GGFGGG--RSSCAFAGGYGGGFGSGYGGGFGGGFG----GGRGMGGGFGGAGGFGGAG 129



>gi|57015418|sp|Q9NZR2|LR1B_HUMAN   Low-density lipoprotein receptor-related protein 1B precursor
            (Low-density lipoprotein receptor-related protein-deleted
            in tumor) (LRP-DIT)
          Length = 4599

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 58/259 (22%), Positives = 90/259 (34%), Gaps = 47/259 (18%)

Query: 684  CPKG--------NPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYT 735
            CP+G        N  S +    +   E     +L+  G L  CH    P    E C+   
Sbjct: 4196 CPEGKYLINGTCNDDSLLDDSCKLTCENGGRCILNEKGDLR-CH--CWPSYSGERCEVNH 4252

Query: 736  CT--CENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSG---LVFKYNVKACNS 790
            C+  C+N   C+ ++LG    +CA   T     +T +CE  C +G   +V   N   C+ 
Sbjct: 4253 CSNYCQNGGTCVPSVLGRPTCSCALGFTGPNCGKT-VCEDFCQNGGTCIVTAGNQPYCHC 4311

Query: 791  S------------CRSLSERDRSCDVEDVPVDGCTCP----------DAMYQNNEGNCVL 828
                         C        SC + D     C CP          D   + + G+C++
Sbjct: 4312 QPEYTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCVRCHGGHCII 4371

Query: 829  -KSQCDCYINDEVMQPGKLIHIDDNKCVCRDGILL---CQIPIDLTLQNCSGGAEYVDCS 884
             K   D + N    +      + D  C       L     +P+ L   N SG      C 
Sbjct: 4372 NKDSEDIFCNCTNGKIASSCQLCDGYCYNGGTCQLDPETNVPVCLCSTNWSG----TQCE 4427

Query: 885  DPKAQRRTNRTCSTRNIPV 903
             P  +   +   STR+I +
Sbjct: 4428 RPAPKSSKSDHISTRSIAI 4446



>gi|9438227|gb|AAF86585.1|   DEAD box RNA helicase [Homo sapiens]
          Length = 724

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 51/195 (26%), Positives = 70/195 (35%), Gaps = 57/195 (29%)

Query: 309 GAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENS------------------- 349
           G  F  RD+G     DN ++   F   GVG S    GF NS                   
Sbjct: 62  GRNFGNRDAGECNKRDNTSTMGGF---GVGKSFGNRGFSNSRFEDGDSSGFWRESSNDCE 118

Query: 350 ------SGISEDSGVILGSSDQHEVELSRTG-------------GNRKRSSDPDEAGNLS 390
                  G S+  G   G++ +      R G             G+     DPDE    +
Sbjct: 119 DNPTRNRGFSKRGGYRDGNNSEASGPYRRGGRGSFRGCRGGFGLGSPNNDLDPDECMQRT 178

Query: 391 PG------SDVSDSG-GNTWSSDSGSG---GGGKSADELGVGASGLN------EFGETGL 434
            G        +S +G G+T  S SGSG   GG K  +E  +  SG N      E GE+  
Sbjct: 179 GGLFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLNEEVITGSGKNSWKSEAEGGESSD 238

Query: 435 SGSEKGSHIPEATPK 449
           +   K ++IP   P+
Sbjct: 239 TQGPKVTYIPPPPPE 253



>gi|20521948|dbj|BAB13408.2|   KIAA1582 protein [Homo sapiens]
          Length = 1740

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 77/349 (22%), Positives = 110/349 (31%), Gaps = 56/349 (16%)

Query: 71  SEDTPAGGFFNSSSSSGDSDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFF 130
           S   PA G  NS  S G+ D      S        A  K G    +GG+  +  PP G  
Sbjct: 302 SPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG----SGGNAWDSGPPAG-- 355

Query: 131 YGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGLKLGAGK 190
            G  + G       + +   GA G              SRS  +   G            
Sbjct: 356 PGILAWGRGSGNNGVGNIHSGAWGHP------------SRSTSNGVNGEW---------- 393

Query: 191 GDAAFGFEVSDSNSFGDTGISSKTVEG-NQTSSSGGSVSIDLGDTSFRSENQFVGGGSLN 249
           G        SD N  G TG  S +V   N T   GG             E+      + +
Sbjct: 394 GKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGG-------------EHMNSWAKAAS 440

Query: 250 SISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDS-----SSSVEKSWLFEFGLG 304
           S +   +   +G G +  G  G  G+       KG           + ++   L   G G
Sbjct: 441 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 500

Query: 305 ET--KGGAEFNFRDS-GSNQSGDNGNSSKDFDGNGVGDSSARN--GFENSSGISEDSGVI 359
           +T  K    + F +S  S +  DNG  +         +S  +N     NS+  S  SG +
Sbjct: 501 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV 560

Query: 360 LGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDS----GGNTWS 404
                           N K  S P   G+    + VS +     G+ WS
Sbjct: 561 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWS 609



>gi|18676590|dbj|BAB84947.1|   FLJ00193 protein [Homo sapiens]
          Length = 491

 Score = 35.0 bits (79), Expect = 0.89
 Identities = 51/181 (28%), Positives = 60/181 (33%), Gaps = 44/181 (24%)

Query: 716 ASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSC 775
           A CH       +   C   TCTC+N   CL    GN V  CA       G+R   C+ SC
Sbjct: 15  ARCHLSCPEGLWGVNCSN-TCTCKNGGTCL-PENGNCV--CAP------GFRGPSCQRSC 64

Query: 776 PSGLVFKYNV--KACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEG----NCVLK 829
             G   K  V  K  N S    S     C      + G T PD       G    NC   
Sbjct: 65  QPGRYGKRCVPCKCANHSFCHPSNGTCYC------LAGWTGPDCSQPCPPGHWGENCAQT 118

Query: 830 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLT----LQNCSGGAEYVDCSD 885
            QC           G   H  D  C+C         P+  T    L+ C  G    +CS 
Sbjct: 119 CQC---------HHGGTCHPQDGSCIC---------PLGWTGHHCLEGCPLGTFGANCSQ 160

Query: 886 P 886
           P
Sbjct: 161 P 161



>gi|4503667|ref|NP_001990.1|   fibrillin 2 (congenital contractural arachnodactyly) [Homo sapiens]
 gi|1345961|sp|P35556|FBN2_HUMAN   Fibrillin 2 precursor
 gi|437972|gb|AAA18950.1|   fibrillin-2
          Length = 2911

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 41/136 (30%), Positives = 48/136 (35%), Gaps = 18/136 (13%)

Query: 371 SRTGGNRKRSSDPDEAGN-LSPGSD--VSDSGGNTWSSDSGSGGGGKSADELGVGASGLN 427
           SR GG       P   GN   PG    +   GGN +S   G GG G  A   G   +GL 
Sbjct: 431 SRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSP--GVGGAGVGAGGQGPIITGLT 488

Query: 428 EFGET------GLSGSEKGSHIPEATPKYSETNAIIGQDIN-------EHIANSKIPGDC 474
              +T        +    G  IP  +    E N    QD N       E  +N    GDC
Sbjct: 489 ILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDC 548

Query: 475 PNAVGKSYEVCEDGIQ 490
            N  G  Y  C  G Q
Sbjct: 549 VNTPGSYYCKCHAGFQ 564



>gi|10257390|gb|AAG15395.1|   serine protease TADG15 [Homo sapiens]
          Length = 855

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 464 CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 521

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 522 ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 577

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 578 LCLSKGNPECDGKEDCSDGSDEKDC 602



>gi|34782939|gb|AAH05826.2|   ST14 protein [Homo sapiens]
          Length = 526

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 135 CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 192

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 193 ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 248

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 249 LCLSKGNPECDGKEDCSDGSDEKDC 273



>gi|17390323|gb|AAH18146.1|   ST14 protein [Homo sapiens]
          Length = 422

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 31  CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 88

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 89  ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 144

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 145 LCLSKGNPECDGKEDCSDGSDEKDC 169



>gi|13938287|gb|AAH07271.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|15080451|gb|AAH11972.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|17511973|gb|AAH18949.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|14424524|gb|AAH09284.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|5803036|ref|NP_006796.1|   heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|20810403|gb|AAH28976.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|20987729|gb|AAH30249.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|15278047|gb|AAH12980.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|12654371|gb|AAH01008.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|17939453|gb|AAH19271.1|   Heterogeneous nuclear ribonucleoprotein A0 [Homo sapiens]
 gi|8134660|sp|Q13151|ROA0_HUMAN   Heterogeneous nuclear ribonucleoprotein A0 (hnRNP A0)
 gi|773644|gb|AAA65094.1|   heterogeneous ribonucleoprotein A0
 gi|48146089|emb|CAG33267.1|   HNRPA0 [Homo sapiens]
          Length = 305

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 37/127 (29%), Positives = 44/127 (34%), Gaps = 10/127 (7%)

Query: 217 GNQTSSSGGSVSIDLGDTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSV 276
           G   SS GG      G    ++     GGG  NS       G  G G N  GG G   S 
Sbjct: 186 GGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGG--GGGYNAYGGGGGGSSY 243

Query: 277 SAEAGFKGFGSDSSSSVEKSWL--FEFGLGETKGGAEFNFRDSGSNQSGDNGNSSKDFDG 334
                  GFG   S S  +S     + G G   GG+ +  R +     G  G       G
Sbjct: 244 GGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGG------G 297

Query: 335 NGVGDSS 341
            G G SS
Sbjct: 298 GGYGGSS 304



>gi|57162675|emb|CAI39902.1|   nucleoporin like 1 [Homo sapiens]
          Length = 463

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 42/173 (24%), Positives = 61/173 (35%), Gaps = 18/173 (10%)

Query: 125 PPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPAVGTGSSGL 184
           P  GF  G   S      KP   F  G T      +      G S   + PA       L
Sbjct: 18  PSSGFGTGLFGS------KPATGFTLGGTNTGTPATTSAATTGFSLGFNKPAASATPFAL 71

Query: 185 KLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSENQFVG 244
            + +             S     TG +   + G   +++  S  + LG           G
Sbjct: 72  PITSTSASGLTLSSALTSTPAASTGFTLNNLGGTTATTTTASTGLSLG-------GALAG 124

Query: 245 -GGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKGFGS-DSSSSVEK 295
            GGSL   +N   +G  G G N +G    + + ++ AG +G G  D SSS +K
Sbjct: 125 LGGSLFQSTN---TGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDK 174



>gi|41150277|ref|XP_370982.1|   PREDICTED: similar to Heterogeneous nuclear ribonucleoprotein A1
           (Helix-destabilizing protein) (Single-strand binding
           protein) (hnRNP core protein A1) (HDP-1)
           (Topoisomerase-inhibitor suppressed) [Homo sapiens]
          Length = 320

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 36/154 (23%), Positives = 55/154 (35%), Gaps = 33/154 (21%)

Query: 257 SGQEGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVEKSWLFEFGLGETKGGAEFNFRD 316
           SG   FG    GG G + +      F G G               G G ++GG  +    
Sbjct: 197 SGSGNFGGGRGGGFGGNDNFGRGGNFSGRG---------------GFGGSRGGGGYGGSG 241

Query: 317 SGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGN 376
            G N  G+        DG+  G   + N F N +  S + G + G + +        GG 
Sbjct: 242 DGYNGFGN--------DGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFEGRSSGPHGGGG 293

Query: 377 RKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSG 410
           +  +   ++ G           GG++ SS  GSG
Sbjct: 294 QYFAKPRNQGG----------YGGSSSSSSYGSG 317



>gi|9714272|emb|CAC01407.1|   double stranded RNA binding nuclear protein, ILF3 [Homo sapiens]
          Length = 591

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 68/271 (25%), Positives = 93/271 (34%), Gaps = 38/271 (14%)

Query: 178 GTGSS--GLKLGAGKGDAAFGFEVSDSNSFGDTGI--SSKTVEGNQTSSSGGSVSIDLGD 233
           G G S  G   G G G A  G  ++    +G  G   +S T   +Q  S+GG        
Sbjct: 340 GRGGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGG-------- 391

Query: 234 TSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGSVSAEAGFKG-FGSDSSSS 292
               S N   GGG           G  G+G    G N  S      AG K   G     S
Sbjct: 392 ---HSGNASGGGGG-------GGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPS 441

Query: 293 VEKSWLFEFGLG-ETKGGAEFNFRDSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSG 351
                   +G G ++  G + ++  S  +  G      K ++ +G G  S  N + NS G
Sbjct: 442 --------YGSGYQSHQGQQQSYNQSLYSNYGPPQGKQKGYN-HGQGSYSYSNSY-NSPG 491

Query: 352 ISEDSGVILGSSDQHEVELSRTGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG 411
               S     S   +     R+GGN   S       + +PGS     GG+   S      
Sbjct: 492 GGGGSDYNYESKFNYSGSGGRSGGNSYGSG----GASYNPGSHGGYGGGSGGGSSYQGKQ 547

Query: 412 GGKSADELGVGASGLNEFGETGLSGSEKGSH 442
           GG S        SG N  G      S +G +
Sbjct: 548 GGYSQSNYNSPGSGQNYSGPPSSYQSSQGGY 578



>gi|11415040|ref|NP_068813.1|   matriptase [Homo sapiens]
 gi|20988875|gb|AAH30532.1|   Matriptase [Homo sapiens]
 gi|6647302|gb|AAD42765.2|   matriptase [Homo sapiens]
 gi|6002714|gb|AAF00109.1|   membrane-type serine protease 1 [Homo sapiens]
 gi|13124575|sp|Q9Y5Y6|ST14_HUMAN   Suppressor of tumorigenicity 14 (Matriptase) (Membrane-type serine
           protease 1) (MT-SP1) (Prostamin) (Serine protease
           TADG-15) (Tumor associated differentially-expressed
           gene-15 protein)
          Length = 855

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 464 CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 521

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 522 ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 577

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 578 LCLSKGNPECDGKEDCSDGSDEKDC 602



>gi|627438|pir||A54105   fibrillin-2 precursor - human
          Length = 2918

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 41/136 (30%), Positives = 48/136 (35%), Gaps = 18/136 (13%)

Query: 371 SRTGGNRKRSSDPDEAGN-LSPGSD--VSDSGGNTWSSDSGSGGGGKSADELGVGASGLN 427
           SR GG       P   GN   PG    +   GGN +S   G GG G  A   G   +GL 
Sbjct: 431 SRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSP--GVGGAGVGAGGQGPIITGLT 488

Query: 428 EFGET------GLSGSEKGSHIPEATPKYSETNAIIGQDIN-------EHIANSKIPGDC 474
              +T        +    G  IP  +    E N    QD N       E  +N    GDC
Sbjct: 489 ILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCIDVDECTSNPCTNGDC 548

Query: 475 PNAVGKSYEVCEDGIQ 490
            N  G  Y  C  G Q
Sbjct: 549 VNTPGSYYCKCHAGFQ 564



>gi|10179932|gb|AAG13949.1|   serine protease SNC19 [Homo sapiens]
          Length = 325

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 125 CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 182

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 183 ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 238

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 239 LCLSKGNPECDGKEDCSDGSDEKDC 263



>gi|12249015|dbj|BAB20376.1|   prostamin [Homo sapiens]
          Length = 855

 Score = 34.7 bits (78), Expect = 1.2
 Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 23/145 (15%)

Query: 756 CAEKETYIVGWRTGLCEHS------CPSGLVFKYNVKACNSS---CRSLSERDRSCDVED 806
           C  KE    GW     +HS      C +G  F    K C      C S+++   + D + 
Sbjct: 464 CIRKELRCDGW-ADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSVNDCGDNSDEQ- 521

Query: 807 VPVDGCTCPDAMYQNNEGNCVLKS-QC----DCYI-NDEVMQPG-KLIHIDDNKCVCRDG 859
               GC+CP   ++ + G C+ KS QC    DC   +DE   P   ++    +   C +G
Sbjct: 522 ----GCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTCTKHTYRCLNG 577

Query: 860 ILLCQ-IPIDLTLQNCSGGAEYVDC 883
           + L +  P     ++CS G++  DC
Sbjct: 578 LCLSKGNPECDGKEDCSDGSDEKDC 602



>gi|45827750|ref|NP_996672.1|   Fraser syndrome 1 isoform 2 [Homo sapiens]
          Length = 1975

 Score = 34.3 bits (77), Expect = 1.5
 Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 41/185 (22%)

Query: 724  PKPYHEE---CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLV 780
            P  Y+ E   CKK   +C   Q       G    +C+  +T +V   TG C  +C  G  
Sbjct: 847  PSGYYAERGACKKCHSSCRTCQ-------GRGPFSCSSCDTNLVLSHTGTCSTTCFPGHY 899

Query: 781  FKYN--VKACNSSCRSLSERDRSCDVED---------VPVDGC-----------TCPDAM 818
               N   + CN+ C S   +       D            + C           TC +  
Sbjct: 900  LDDNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECD 959

Query: 819  YQNNEGNCVLKSQCDCYINDEVMQPGKLI-------HIDDNKCVCRDGILLCQIPIDLTL 871
            +  +  +  LK+ C   ++  V+Q G  +       + D   C C    L CQ P + T 
Sbjct: 960  WSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQDSGLCKCDSYCLQCQGPHECT- 1018

Query: 872  QNCSG 876
              C G
Sbjct: 1019 -RCKG 1022






  Database: All non-redundant GenBank CDS
  translations+PDB+SwissProt+PIR+PRF excluding environmental samples
    Posted date:  Mar 15, 2005 10:11 AM
  Number of letters in database: 802,797,248
  Number of sequences in database:  2,367,365
  
Lambda     K      H
   0.313    0.132    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,463,235
Number of Sequences: 2367365
Number of extensions: 1004290
Number of successful extensions: 2574
Number of sequences better than 10.0: 97
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 2145
Number of HSP's gapped (non-prelim): 316
length of query: 1144
length of database: 46,038,991
effective HSP length: 119
effective length of query: 1025
effective length of database: 30,552,212
effective search space: 31316017300
effective search space used: 31316017300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)







 


 
Format
  


 


 
Show
  Graphical OverviewLinkoutSequence RetrievalNCBI-giAlignmentPSSMBioseq in HTMLPlain textASN.1XMLformat


 


 
Use new formatter
  Masking CharacterDefault(X for protein, n for nucleotide)Lower Case
Masking ColorBlackGreyRed



 


 
Number of:
  Descriptions01050100250500
Alignments01050100250500



 


 
Alignment view
  PairwisePairwise with identitiesquery-anchored with identitiesquery-anchored without identitiesflat query-anchored with identitiesflat query-anchored without identitiesHit Table


 


 
Format for PSI-BLAST
  with inclusion threshold:


 


 
Limit results by entrez query
   or select from:All organismsViruses [ORGN]Archaea [ORGN]Bacteria [ORGN]Eukaryota [ORGN]Viridiplantae [ORGN]Fungi [ORGN]Metazoa [ORGN]Arthropoda [ORGN]Vertebrata [ORGN]Mammalia [ORGN]Rodentia [ORGN]Primates [ORGN]-------------------Aeropyrum pernix [ORGN]Aquifex aeolicus [ORGN]Arabidopsis thaliana [ORGN]Bacillus subtilis [ORGN]Bos taurus [ORGN]Caenorhabditis elegans [ORGN]Canis familiaris[ORGN]Danio rerio [ORGN]Dictyostelium discoideum [ORGN]Drosophila melanogaster [ORGN]Escherichia coli [ORGN]Gallus gallus [ORGN]Homo sapiens [ORGN]Human immunodeficiency virus type 1 [ORGN]Methanococcus jannaschii [ORGN]Mus musculus [ORGN]Oryctolagus cuniculus [ORGN]Oryza sativa [ORGN]Ovis aries [ORGN]Plasmodium falciparum [ORGN]Rattus norvegicus [ORGN]Saccharomyces cerevisiae [ORGN]Schizosaccharomyces pombe [ORGN]Xenopus tropicalis[ORGN]Simian immunodeficiency virus [ORGN]Sus scrofa[ORGN]Synechocystis PCC6803 [ORGN]Takifugu rubripes [ORGN]Xenopus laevis [ORGN]Zea mays [ORGN]


 


 
Expect value range:
    







 or