BLASTP 2.2.10 [Oct-19-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. RID: 1111132484-5878-130412826072.BLASTQ2 Query= FGENESH: 4 8 exon (s) 203739 - 236802 689 aa, chain - (689 letters) Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters If you have any problems or questions with the results of this search please refer to the BLAST FAQs Taxonomy reports
RID: 1111132484-5878-130412826072.BLASTQ2
Query= FGENESH: 4 8 exon (s) 203739 - 236802 689 aa, chain - (689 letters)
Database: Non-redundant SwissProt sequences 164,271 sequences; 60,490,055 total letters
If you have any problems or questions with the results of this search please refer to the BLAST FAQs
Taxonomy reports
Score E Sequences producing significant alignments: (bits) Value gi|60391728|sp|Q6Q788|APOA5_HUMAN Apolipoprotein A-V precur... 690 0.0 gi|114006|sp|P06727|APOA4_HUMAN Apolipoprotein A-IV precurs... 394 e-110 gi|113992|sp|P02647|APOA1_HUMAN Apolipoprotein A-I precurso... 71 1e-12 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 61 1e-09 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 59 4e-09 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 55 8e-08 gi|114039|sp|P02649|APOE_HUMAN Apolipoprotein E precursor (... 55 1e-07 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 52 9e-07 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 51 2e-06 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 50 3e-06 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 49 4e-06 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 49 4e-06 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 49 8e-06 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 49 8e-06 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 49 8e-06 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 48 1e-05 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 47 2e-05 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 47 2e-05 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 46 4e-05 gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentri... 46 5e-05 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 45 6e-05 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 45 6e-05 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 45 6e-05 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 45 8e-05 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 45 1e-04 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 44 2e-04 gi|464541|sp|P35241|RADI_HUMAN Radixin 43 3e-04 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 42 0.001 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 42 0.001 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 42 0.001 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 41 0.001 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 41 0.001 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 41 0.001 gi|42558938|sp|Q8TD31|HCR_HUMAN Alpha helical coiled-coil r... 40 0.002 gi|37537846|sp|Q9H8L6|MRN2_HUMAN Multimerin 2 precursor (EM... 40 0.002 gi|2501668|sp|Q13474|DRP2_HUMAN Dystrophin-related protein 2 39 0.006 gi|730299|sp|P41219|PERI_HUMAN Peripherin 39 0.008 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 39 0.008 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 38 0.013 gi|23822112|sp|Q9P2E9|RRB1_HUMAN Ribosome-binding protein 1... 38 0.013 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 37 0.017 gi|119862|sp|P06734|FCER2_HUMAN Low affinity immunoglobulin... 37 0.017 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 37 0.017 gi|29337005|sp|Q9UQE7|SMC3_HUMAN Structural maintenance of ... 37 0.023 gi|41688595|sp|Q9UJC3|HOOK1_HUMAN Hook homolog 1 (h-hook1) ... 37 0.023 gi|2501084|sp|Q16623|STX1A_HUMAN Syntaxin-1A (Neuron-specif... 37 0.023 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 37 0.030 gi|125962|sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin) 36 0.039 gi|47117086|sp|P61266|STX1C_HUMAN Syntaxin-1B2 36 0.039 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 36 0.039 gi|23831094|sp|O00291|HIP1_HUMAN Huntingtin interacting pro... 36 0.039 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 36 0.039 gi|13123943|sp|O43707|ACTN4_HUMAN Alpha-actinin 4 (Non-musc... 36 0.051 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 36 0.051 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 35 0.066 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 35 0.066 gi|2501085|sp|Q15531|STX1B_HUMAN Syntaxin-1B1 (Syntaxin 1B) 35 0.066 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 35 0.066 gi|26400672|sp|Q96F44|TRI11_HUMAN Tripartite motif protein ... 35 0.066 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 35 0.066 gi|547750|sp|P35900|K1CT_HUMAN Keratin, type I cytoskeletal... 35 0.087 gi|32470611|sp|Q08379|GOA2_HUMAN Golgi autoantigen, golgin ... 35 0.087 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 35 0.087 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 35 0.11 gi|547749|sp|P13645|K1CJ_HUMAN Keratin, type I cytoskeletal... 35 0.11 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 34 0.15 gi|125081|sp|P19012|K1CO_HUMAN Keratin, type I cytoskeletal... 34 0.15 gi|12643547|sp|O15519|CFLA_HUMAN CASP8 and FADD-like apopto... 34 0.15 gi|400793|sp|Q00722|PIB2_HUMAN 1-phosphatidylinositol-4,5-b... 34 0.15 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 34 0.15 gi|2495703|sp|Q14139|UB4A_HUMAN Ubiquitin conjugation facto... 34 0.15 gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, eryth... 34 0.15 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 34 0.19 gi|33860140|sp|Q13625|ASP2_HUMAN Apoptosis stimulating of p... 34 0.19 gi|2497600|sp|Q13751|LAMB3_HUMAN Laminin beta-3 chain precu... 33 0.25 gi|1730573|sp|Q01970|PIB3_HUMAN 1-phosphatidylinositol-4,5-... 33 0.25 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 33 0.25 gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting pro... 33 0.25 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 33 0.25 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 33 0.25 gi|41688581|sp|Q86VS8|HOK3_HUMAN Hook homolog 3 (hHK3) 33 0.25 gi|47117845|sp|P32856|EPMO_HUMAN Epimorphin (Syntaxin 2) 33 0.33 gi|51704330|sp|Q93045|STN2_HUMAN Stathmin 2 (SCG10 protein)... 33 0.33 gi|56405385|sp|Q9HCM9|TM39_HUMAN Tripartite motif protein 3... 33 0.33 gi|46397807|sp|O76014|K1M7_HUMAN Keratin, type I cuticular ... 33 0.33 gi|41688592|sp|Q96ED9|HOK2_HUMAN Hook homolog 2 (h-hook2) (... 33 0.33 gi|41702296|sp|Q8NI27|THO2_HUMAN THO complex subunit 2 (Tho2) 33 0.33 gi|37537873|sp|Q9Y6C2|EMIL1_HUMAN EMILIN 1 precursor (Elast... 33 0.33 gi|38605067|sp|Q9NSB8|HOM2_HUMAN Homer protein homolog 2 (H... 33 0.43 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 33 0.43 gi|13123953|sp|Q9Y6Q5|AP1M2_HUMAN Adaptor-related protein c... 33 0.43 gi|55976724|sp|Q7Z7L9|ZSCA2_HUMAN Zinc finger and SCAN doma... 33 0.43 gi|134798|sp|P11277|SPTB1_HUMAN Spectrin beta chain, erythr... 33 0.43 gi|13431284|sp|Q9UPM8|A4E1_HUMAN Adapter-related protein co... 33 0.43 gi|26006960|sp|O75955|FLOT1_HUMAN Flotillin-1 32 0.56 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 32 0.56 gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p1... 32 0.56 gi|20978868|sp|Q9BY12|Z291_HUMAN Zinc finger protein 291 32 0.56 gi|1346343|sp|P04264|K2C1_HUMAN Keratin, type II cytoskelet... 32 0.56 gi|27923958|sp|O94833|BPAEA_HUMAN Bullous pemphigoid antige... 32 0.56 gi|12230855|sp|Q99543|ZRF1_HUMAN Zuotin related factor-1 (M... 32 0.56 gi|417216|sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquit... 32 0.73 gi|23503078|sp|Q03252|LAM2_HUMAN Lamin B2 32 0.73 gi|46396501|sp|Q9BRK4|LZT2_HUMAN Leucine zipper putative tu... 32 0.73 gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 32 0.73 gi|18266794|sp|O76015|K1M8_HUMAN Keratin, type I cuticular ... 32 0.73 gi|32699621|sp|Q9NZW0|GOG67_HUMAN Golgi autoantigen golgin-... 32 0.73 gi|37537841|sp|Q9BXX0|EMIL2_HUMAN EMILIN 2 precursor (Elast... 32 0.73 gi|56749614|sp|Q6NZI2|PTRF_HUMAN Polymerase I and transcrip... 32 0.96 gi|48428272|sp|Q9UIF7|MUTYH_HUMAN A/G-specific adenine DNA ... 32 0.96 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 32 0.96 gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,... 32 0.96 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 32 0.96 gi|48474780|sp|P78386|K2H5_HUMAN Keratin, type II cuticular... 32 0.96 gi|30316105|sp|Q96PK2|MAC4_HUMAN Microtubule-actin crosslin... 32 0.96 gi|51316936|sp|Q9UPW8|U13A_HUMAN Unc-13 homolog A (Munc13-1) 32 0.96 gi|25091514|sp|O43895|XPP2_HUMAN Xaa-Pro aminopeptidase 2 p... 31 1.3 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 31 1.3 gi|543742|sp|P35609|AAC2_HUMAN Alpha-actinin 2 (Alpha actin... 31 1.3 gi|6175045|sp|Q13277|STX3_HUMAN Syntaxin-3 31 1.3 gi|6016414|sp|Q14532|K1M2_HUMAN Keratin, type I cuticular H... 31 1.3 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 31 1.3 gi|25452905|sp|Q9H501|CT06_HUMAN Hypothetical protein C20orf6 31 1.6 gi|38605459|sp|Q9C035|TRM5_HUMAN Tripartite motif protein 5... 31 1.6 gi|13959419|sp|Q9UJF2|NGAP_HUMAN Ras GTPase-activating prot... 31 1.6 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 31 1.6 gi|122824|sp|P13196|HEM1_HUMAN 5-aminolevulinate synthase, ... 31 1.6 gi|8928247|sp|Q15185|TEBP_HUMAN Telomerase-binding protein ... 31 1.6 gi|22096362|sp|P54252|MJD1_HUMAN Machado-Joseph disease pro... 31 1.6 gi|21362900|sp|Q9BYV6|RN29_HUMAN RING finger protein 29 (Mu... 30 2.1 gi|20455319|sp|Q92994|TF3B_HUMAN Transcription factor IIIB ... 30 2.1 gi|37999757|sp|Q96PP8|GBP5_HUMAN Interferon-induced guanyla... 30 2.1 gi|134461|sp|P05060|SCG1_HUMAN Secretogranin-1 precursor (S... 30 2.1 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 30 2.1 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 30 2.1 gi|25453223|sp|Q9ULU4|PKCB_HUMAN Protein kinase C binding p... 30 2.1 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 30 2.1 gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M prote... 30 2.1 gi|8134735|sp|O60664|M6P1_HUMAN Mannose-6-phosphate recepto... 30 2.1 gi|41688524|sp|Q9UMD9|CA1G_HUMAN Collagen alpha 1(XVII) cha... 30 2.1 gi|1708851|sp|P55268|LMB2_HUMAN Laminin beta-2 chain precur... 30 2.1 gi|23396777|sp|Q9Y6Q9|NCOA3_HUMAN Nuclear receptor coactiva... 30 2.8 gi|20139068|sp|Q96PB7|NOE3_HUMAN Noelin 3 precursor (Olfact... 30 2.8 gi|51338744|sp|O75426|FX24_HUMAN F-box only protein 24 30 2.8 gi|123408|sp|P28069|PIT1_HUMAN Pituitary-specific positive ... 30 2.8 gi|12643528|sp|O00311|CDC7_HUMAN Cell division cycle 7-rela... 30 2.8 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 30 2.8 gi|6225268|sp|O60610|DIAP1_HUMAN Diaphanous protein homolog... 30 2.8 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 30 2.8 gi|48474671|sp|Q9NSB2|K2H4_HUMAN Keratin, type II cuticular... 30 2.8 gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein ty... 30 3.6 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 30 3.6 gi|132517|sp|P14373|RFP_HUMAN Zinc-finger protein RFP (Ret ... 30 3.6 gi|48474260|sp|O43790|KRHB6_HUMAN Keratin, type II cuticula... 30 3.6 gi|47606192|sp|Q8WV44|TM41_HUMAN Tripartite motif protein 41 30 3.6 gi|14916980|sp|P26232|CTN2_HUMAN Alpha-2 catenin (Alpha-cat... 30 3.6 gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-... 30 3.6 gi|23396625|sp|Q9NQT8|K13B_HUMAN Kinesin-like protein KIF13... 30 3.6 gi|51701437|sp|Q8TF61|FBX41_HUMAN F-box only protein 41 30 3.6 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 30 3.6 gi|47606049|sp|Q9H5N1|RAP2_HUMAN Rab GTPase binding effecto... 30 3.6 gi|1171955|sp|P42338|P11B_HUMAN Phosphatidylinositol-4,5-bi... 29 4.8 gi|1346344|sp|P02538|K2C6A_HUMAN Keratin, type II cytoskele... 29 4.8 gi|23503075|sp|P08779|K1CP_HUMAN Keratin, type I cytoskelet... 29 4.8 gi|29427676|sp|Q16891|IMMT_HUMAN Mitochondrial inner membra... 29 4.8 gi|46397468|sp|Q14533|K2H1_HUMAN Keratin, type II cuticular... 29 4.8 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 29 4.8 gi|37999758|sp|Q96PP9|GBP4_HUMAN Guanylate binding protein 4 29 4.8 gi|20981708|sp|P47972|NPTX2_HUMAN Neuronal pentraxin-2 prec... 29 6.2 gi|18202738|sp|Q9BXS5|AP1M1_HUMAN Adaptor-related protein c... 29 6.2 gi|6136547|sp|O60299|Y552_HUMAN Hypothetical protein KIAA0552 29 6.2 gi|48475013|sp|Q9UMX0|UBQ1_HUMAN Ubiquilin 1 (Protein linki... 29 6.2 gi|46397817|sp|P12814|AAC1_HUMAN Alpha-actinin 1 (Alpha-act... 29 6.2 gi|34925430|sp|Q9HCN4|XAB1_HUMAN XPA-binding protein 1 (HUS... 29 6.2 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 29 6.2 gi|56417894|sp|Q8NE71|ABF1_HUMAN ATP-binding cassette, sub-... 29 6.2 gi|2497603|sp|Q13753|LMG2_HUMAN Laminin gamma-2 chain precu... 29 6.2 gi|20455507|sp|P07910|HNRPC_HUMAN Heterogeneous nuclear rib... 29 6.2 gi|2506774|sp|P05787|K2C8_HUMAN Keratin, type II cytoskelet... 29 6.2 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 28 8.1 gi|25014073|sp|O43615|TIM44_HUMAN Import inner membrane tra... 28 8.1 gi|1710877|sp|P48594|SCCA2_HUMAN Squamous cell carcinoma an... 28 8.1 gi|50401600|sp|Q8N0X7|SP20_HUMAN Spartin (Trans-activated b... 28 8.1 gi|37999907|sp|Q9P275|UBP36_HUMAN Ubiquitin carboxyl-termin... 28 8.1 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 28 8.1 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 28 8.1 gi|13432173|sp|P02533|K1CN_HUMAN Keratin, type I cytoskelet... 28 8.1 gi|56757580|sp|P13647|K2C5_HUMAN Keratin, type II cytoskele... 28 8.1 gi|25009281|sp|Q9P2P6|STR9_HUMAN StAR-related lipid transfe... 28 8.1 gi|12230848|sp|O95049|ZO3_HUMAN Tight junction protein ZO-3... 28 8.1 Alignments
Score E Sequences producing significant alignments: (bits) Value gi|60391728|sp|Q6Q788|APOA5_HUMAN Apolipoprotein A-V precur... 690 0.0 gi|114006|sp|P06727|APOA4_HUMAN Apolipoprotein A-IV precurs... 394 e-110 gi|113992|sp|P02647|APOA1_HUMAN Apolipoprotein A-I precurso... 71 1e-12 gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Cen... 61 1e-09 gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmusc... 59 4e-09 gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast sk... 55 8e-08 gi|114039|sp|P02649|APOE_HUMAN Apolipoprotein E precursor (... 55 1e-07 gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skele... 52 9e-07 gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smoot... 51 2e-06 gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus... 50 3e-06 gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac ... 49 4e-06 gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (He... 49 4e-06 gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory fac... 49 8e-06 gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmus... 49 8e-06 gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin ... 49 8e-06 gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin 48 1e-05 gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skelet... 47 2e-05 gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin... 47 2e-05 gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker p... 46 4e-05 gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentri... 46 5e-05 gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skelet... 45 6e-05 gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR 45 6e-05 gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skelet... 45 6e-05 gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac... 45 8e-05 gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeleta... 45 1e-04 gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A... 44 2e-04 gi|464541|sp|P35241|RADI_HUMAN Radixin 43 3e-04 gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precu... 42 0.001 gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-assoc... 42 0.001 gi|118685|sp|P11532|DMD_HUMAN Dystrophin 42 0.001 gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 41 0.001 gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor... 41 0.001 gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) 41 0.001 gi|42558938|sp|Q8TD31|HCR_HUMAN Alpha helical coiled-coil r... 40 0.002 gi|37537846|sp|Q9H8L6|MRN2_HUMAN Multimerin 2 precursor (EM... 40 0.002 gi|2501668|sp|Q13474|DRP2_HUMAN Dystrophin-related protein 2 39 0.006 gi|730299|sp|P41219|PERI_HUMAN Peripherin 39 0.008 gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing ... 39 0.008 gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin ... 38 0.013 gi|23822112|sp|Q9P2E9|RRB1_HUMAN Ribosome-binding protein 1... 38 0.013 gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein... 37 0.017 gi|119862|sp|P06734|FCER2_HUMAN Low affinity immunoglobulin... 37 0.017 gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interact... 37 0.017 gi|29337005|sp|Q9UQE7|SMC3_HUMAN Structural maintenance of ... 37 0.023 gi|41688595|sp|Q9UJC3|HOOK1_HUMAN Hook homolog 1 (h-hook1) ... 37 0.023 gi|2501084|sp|Q16623|STX1A_HUMAN Syntaxin-1A (Neuron-specif... 37 0.023 gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 37 0.030 gi|125962|sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin) 36 0.039 gi|47117086|sp|P61266|STX1C_HUMAN Syntaxin-1B2 36 0.039 gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) 36 0.039 gi|23831094|sp|O00291|HIP1_HUMAN Huntingtin interacting pro... 36 0.039 gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) 36 0.039 gi|13123943|sp|O43707|ACTN4_HUMAN Alpha-actinin 4 (Non-musc... 36 0.051 gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of ... 36 0.051 gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of... 35 0.066 gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP... 35 0.066 gi|2501085|sp|Q15531|STX1B_HUMAN Syntaxin-1B1 (Syntaxin 1B) 35 0.066 gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9... 35 0.066 gi|26400672|sp|Q96F44|TRI11_HUMAN Tripartite motif protein ... 35 0.066 gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein ty... 35 0.066 gi|547750|sp|P35900|K1CT_HUMAN Keratin, type I cytoskeletal... 35 0.087 gi|32470611|sp|Q08379|GOA2_HUMAN Golgi autoantigen, golgin ... 35 0.087 gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (... 35 0.087 gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like ... 35 0.11 gi|547749|sp|P13645|K1CJ_HUMAN Keratin, type I cytoskeletal... 35 0.11 gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin ... 34 0.15 gi|125081|sp|P19012|K1CO_HUMAN Keratin, type I cytoskeletal... 34 0.15 gi|12643547|sp|O15519|CFLA_HUMAN CASP8 and FADD-like apopto... 34 0.15 gi|400793|sp|Q00722|PIB2_HUMAN 1-phosphatidylinositol-4,5-b... 34 0.15 gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L prote... 34 0.15 gi|2495703|sp|Q14139|UB4A_HUMAN Ubiquitin conjugation facto... 34 0.15 gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, eryth... 34 0.15 gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 34 0.19 gi|33860140|sp|Q13625|ASP2_HUMAN Apoptosis stimulating of p... 34 0.19 gi|2497600|sp|Q13751|LAMB3_HUMAN Laminin beta-3 chain precu... 33 0.25 gi|1730573|sp|Q01970|PIB3_HUMAN 1-phosphatidylinositol-4,5-... 33 0.25 gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation init... 33 0.25 gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting pro... 33 0.25 gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex prote... 33 0.25 gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein... 33 0.25 gi|41688581|sp|Q86VS8|HOK3_HUMAN Hook homolog 3 (hHK3) 33 0.25 gi|47117845|sp|P32856|EPMO_HUMAN Epimorphin (Syntaxin 2) 33 0.33 gi|51704330|sp|Q93045|STN2_HUMAN Stathmin 2 (SCG10 protein)... 33 0.33 gi|56405385|sp|Q9HCM9|TM39_HUMAN Tripartite motif protein 3... 33 0.33 gi|46397807|sp|O76014|K1M7_HUMAN Keratin, type I cuticular ... 33 0.33 gi|41688592|sp|Q96ED9|HOK2_HUMAN Hook homolog 2 (h-hook2) (... 33 0.33 gi|41702296|sp|Q8NI27|THO2_HUMAN THO complex subunit 2 (Tho2) 33 0.33 gi|37537873|sp|Q9Y6C2|EMIL1_HUMAN EMILIN 1 precursor (Elast... 33 0.33 gi|38605067|sp|Q9NSB8|HOM2_HUMAN Homer protein homolog 2 (H... 33 0.43 gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domai... 33 0.43 gi|13123953|sp|Q9Y6Q5|AP1M2_HUMAN Adaptor-related protein c... 33 0.43 gi|55976724|sp|Q7Z7L9|ZSCA2_HUMAN Zinc finger and SCAN doma... 33 0.43 gi|134798|sp|P11277|SPTB1_HUMAN Spectrin beta chain, erythr... 33 0.43 gi|13431284|sp|Q9UPM8|A4E1_HUMAN Adapter-related protein co... 33 0.43 gi|26006960|sp|O75955|FLOT1_HUMAN Flotillin-1 32 0.56 gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isofor... 32 0.56 gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p1... 32 0.56 gi|20978868|sp|Q9BY12|Z291_HUMAN Zinc finger protein 291 32 0.56 gi|1346343|sp|P04264|K2C1_HUMAN Keratin, type II cytoskelet... 32 0.56 gi|27923958|sp|O94833|BPAEA_HUMAN Bullous pemphigoid antige... 32 0.56 gi|12230855|sp|Q99543|ZRF1_HUMAN Zuotin related factor-1 (M... 32 0.56 gi|417216|sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquit... 32 0.73 gi|23503078|sp|Q03252|LAM2_HUMAN Lamin B2 32 0.73 gi|46396501|sp|Q9BRK4|LZT2_HUMAN Leucine zipper putative tu... 32 0.73 gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 32 0.73 gi|18266794|sp|O76015|K1M8_HUMAN Keratin, type I cuticular ... 32 0.73 gi|32699621|sp|Q9NZW0|GOG67_HUMAN Golgi autoantigen golgin-... 32 0.73 gi|37537841|sp|Q9BXX0|EMIL2_HUMAN EMILIN 2 precursor (Elast... 32 0.73 gi|56749614|sp|Q6NZI2|PTRF_HUMAN Polymerase I and transcrip... 32 0.96 gi|48428272|sp|Q9UIF7|MUTYH_HUMAN A/G-specific adenine DNA ... 32 0.96 gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) 32 0.96 gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,... 32 0.96 gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crossli... 32 0.96 gi|48474780|sp|P78386|K2H5_HUMAN Keratin, type II cuticular... 32 0.96 gi|30316105|sp|Q96PK2|MAC4_HUMAN Microtubule-actin crosslin... 32 0.96 gi|51316936|sp|Q9UPW8|U13A_HUMAN Unc-13 homolog A (Munc13-1) 32 0.96 gi|25091514|sp|O43895|XPP2_HUMAN Xaa-Pro aminopeptidase 2 p... 31 1.3 gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein ... 31 1.3 gi|543742|sp|P35609|AAC2_HUMAN Alpha-actinin 2 (Alpha actin... 31 1.3 gi|6175045|sp|Q13277|STX3_HUMAN Syntaxin-3 31 1.3 gi|6016414|sp|Q14532|K1M2_HUMAN Keratin, type I cuticular H... 31 1.3 gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelop... 31 1.3 gi|25452905|sp|Q9H501|CT06_HUMAN Hypothetical protein C20orf6 31 1.6 gi|38605459|sp|Q9C035|TRM5_HUMAN Tripartite motif protein 5... 31 1.6 gi|13959419|sp|Q9UJF2|NGAP_HUMAN Ras GTPase-activating prot... 31 1.6 gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) 31 1.6 gi|122824|sp|P13196|HEM1_HUMAN 5-aminolevulinate synthase, ... 31 1.6 gi|8928247|sp|Q15185|TEBP_HUMAN Telomerase-binding protein ... 31 1.6 gi|22096362|sp|P54252|MJD1_HUMAN Machado-Joseph disease pro... 31 1.6 gi|21362900|sp|Q9BYV6|RN29_HUMAN RING finger protein 29 (Mu... 30 2.1 gi|20455319|sp|Q92994|TF3B_HUMAN Transcription factor IIIB ... 30 2.1 gi|37999757|sp|Q96PP8|GBP5_HUMAN Interferon-induced guanyla... 30 2.1 gi|134461|sp|P05060|SCG1_HUMAN Secretogranin-1 precursor (S... 30 2.1 gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precurs... 30 2.1 gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domai... 30 2.1 gi|25453223|sp|Q9ULU4|PKCB_HUMAN Protein kinase C binding p... 30 2.1 gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal... 30 2.1 gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M prote... 30 2.1 gi|8134735|sp|O60664|M6P1_HUMAN Mannose-6-phosphate recepto... 30 2.1 gi|41688524|sp|Q9UMD9|CA1G_HUMAN Collagen alpha 1(XVII) cha... 30 2.1 gi|1708851|sp|P55268|LMB2_HUMAN Laminin beta-2 chain precur... 30 2.1 gi|23396777|sp|Q9Y6Q9|NCOA3_HUMAN Nuclear receptor coactiva... 30 2.8 gi|20139068|sp|Q96PB7|NOE3_HUMAN Noelin 3 precursor (Olfact... 30 2.8 gi|51338744|sp|O75426|FX24_HUMAN F-box only protein 24 30 2.8 gi|123408|sp|P28069|PIT1_HUMAN Pituitary-specific positive ... 30 2.8 gi|12643528|sp|O00311|CDC7_HUMAN Cell division cycle 7-rela... 30 2.8 gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 ... 30 2.8 gi|6225268|sp|O60610|DIAP1_HUMAN Diaphanous protein homolog... 30 2.8 gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin ... 30 2.8 gi|48474671|sp|Q9NSB2|K2H4_HUMAN Keratin, type II cuticular... 30 2.8 gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein ty... 30 3.6 gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin 30 3.6 gi|132517|sp|P14373|RFP_HUMAN Zinc-finger protein RFP (Ret ... 30 3.6 gi|48474260|sp|O43790|KRHB6_HUMAN Keratin, type II cuticula... 30 3.6 gi|47606192|sp|Q8WV44|TM41_HUMAN Tripartite motif protein 41 30 3.6 gi|14916980|sp|P26232|CTN2_HUMAN Alpha-2 catenin (Alpha-cat... 30 3.6 gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-... 30 3.6 gi|23396625|sp|Q9NQT8|K13B_HUMAN Kinesin-like protein KIF13... 30 3.6 gi|51701437|sp|Q8TF61|FBX41_HUMAN F-box only protein 41 30 3.6 gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit as... 30 3.6 gi|47606049|sp|Q9H5N1|RAP2_HUMAN Rab GTPase binding effecto... 30 3.6 gi|1171955|sp|P42338|P11B_HUMAN Phosphatidylinositol-4,5-bi... 29 4.8 gi|1346344|sp|P02538|K2C6A_HUMAN Keratin, type II cytoskele... 29 4.8 gi|23503075|sp|P08779|K1CP_HUMAN Keratin, type I cytoskelet... 29 4.8 gi|29427676|sp|Q16891|IMMT_HUMAN Mitochondrial inner membra... 29 4.8 gi|46397468|sp|Q14533|K2H1_HUMAN Keratin, type II cuticular... 29 4.8 gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein ty... 29 4.8 gi|37999758|sp|Q96PP9|GBP4_HUMAN Guanylate binding protein 4 29 4.8 gi|20981708|sp|P47972|NPTX2_HUMAN Neuronal pentraxin-2 prec... 29 6.2 gi|18202738|sp|Q9BXS5|AP1M1_HUMAN Adaptor-related protein c... 29 6.2 gi|6136547|sp|O60299|Y552_HUMAN Hypothetical protein KIAA0552 29 6.2 gi|48475013|sp|Q9UMX0|UBQ1_HUMAN Ubiquilin 1 (Protein linki... 29 6.2 gi|46397817|sp|P12814|AAC1_HUMAN Alpha-actinin 1 (Alpha-act... 29 6.2 gi|34925430|sp|Q9HCN4|XAB1_HUMAN XPA-binding protein 1 (HUS... 29 6.2 gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 29 6.2 gi|56417894|sp|Q8NE71|ABF1_HUMAN ATP-binding cassette, sub-... 29 6.2 gi|2497603|sp|Q13753|LMG2_HUMAN Laminin gamma-2 chain precu... 29 6.2 gi|20455507|sp|P07910|HNRPC_HUMAN Heterogeneous nuclear rib... 29 6.2 gi|2506774|sp|P05787|K2C8_HUMAN Keratin, type II cytoskelet... 29 6.2 gi|55977767|sp|P08670|VIME_HUMAN Vimentin 28 8.1 gi|25014073|sp|O43615|TIM44_HUMAN Import inner membrane tra... 28 8.1 gi|1710877|sp|P48594|SCCA2_HUMAN Squamous cell carcinoma an... 28 8.1 gi|50401600|sp|Q8N0X7|SP20_HUMAN Spartin (Trans-activated b... 28 8.1 gi|37999907|sp|Q9P275|UBP36_HUMAN Ubiquitin carboxyl-termin... 28 8.1 gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of ... 28 8.1 gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motilit... 28 8.1 gi|13432173|sp|P02533|K1CN_HUMAN Keratin, type I cytoskelet... 28 8.1 gi|56757580|sp|P13647|K2C5_HUMAN Keratin, type II cytoskele... 28 8.1 gi|25009281|sp|Q9P2P6|STR9_HUMAN StAR-related lipid transfe... 28 8.1 gi|12230848|sp|O95049|ZO3_HUMAN Tight junction protein ZO-3... 28 8.1
>gi|60391728|sp|Q6Q788|APOA5_HUMAN Apolipoprotein A-V precursor (Apolipoprotein A5) (ApoAV) (ApoA-V) (Regeneration associated protein 3) (UNQ411/PRO773) Length = 366 Score = 690 bits (1780), Expect = 0.0 Identities = 356/394 (90%), Positives = 356/394 (90%), Gaps = 28/394 (7%) Query: 296 MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDD 355 MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPA Sbjct: 1 MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPA------ 54 Query: 356 LGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM 415 TLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM Sbjct: 55 ----------------------TLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM 92 Query: 416 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR 475 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR Sbjct: 93 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR 152 Query: 476 VVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRS 535 VVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRS Sbjct: 153 VVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRS 212 Query: 536 VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXP 595 VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAF P Sbjct: 213 VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272 Query: 596 DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTD 655 DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTD Sbjct: 273 DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTD 332 Query: 656 SGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP 689 SGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP Sbjct: 333 SGKVLSKLQARLDDLWEDITHSLHDQGHSHLGDP 366
Score = 71.2 bits (173), Expect = 1e-12 Identities = 56/240 (23%), Positives = 99/240 (41%), Gaps = 33/240 (13%) Query: 23 SADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYA 82 SA Q WDYFSQ S + K VE + + ++ RE L+ L Sbjct: 19 SATQARKGFWDYFSQTSGD-KGRVEQIHQQKMA-------------REPATLKDSLEQDL 64 Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 M + L + LRP + ++ Q+ ++ +L + +EE++ Sbjct: 65 NNMNKFLEK--------LRPLSGSEAPRLPQDPVGMRRQL-----------QEELEEVKA 105 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN 202 L PY + E + LEGL Q+K +L +++ +EL+++L + ED + L G Sbjct: 106 RLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGG 165 Query: 203 TEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLS 262 + L L + F+ PY E+ + + +++L + + PHA LS Sbjct: 166 VDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLS 225
Score = 68.6 bits (166), Expect = 7e-12 Identities = 60/239 (25%), Positives = 108/239 (45%), Gaps = 26/239 (10%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRP 102 ++ E L++ + Q + G E LR+QL PY + + LQ LR Sbjct: 94 RQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRV 153 Query: 103 HADELKAKIDQNVEE-------LKGRLT-----------PYADEFKVKIDQTVEELRRSL 144 ++ KA++ V+E L+ R+ PYA+ I + V+EL RS+ Sbjct: 154 VGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSV 213 Query: 145 APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE 204 AP+A + +L+ ++ L+ ++ A+ L ARI + ++LR+ L+ G E Sbjct: 214 APHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGT-----GTEE 268 Query: 205 GLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF 263 G L + Q+++ FR+ F +A+ Q+ E+++Q+L P GH +F Sbjct: 269 GAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAP---PPPGHSAF 324
Score = 44.7 bits (104), Expect = 1e-04 Identities = 55/276 (19%), Positives = 115/276 (41%), Gaps = 38/276 (13%) Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 245 ++L PL+ L + G+++ L E ++EE + R++PY ++ + +E Sbjct: 72 EKLRPLSGSEAPRLPQDPVGMRRQLQE-------ELEEVKARLQPYMAEAHELVGWNLEG 124 Query: 246 LRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTW 305 LRQ+L P+ D+ ++ ++L+++ V E A + + Sbjct: 125 LRQQLKPYTMDLMEQVALRVQELQEQL----------------RVVGEDTKAQLLGGVDE 168 Query: 306 ALALLSAFSAT------QARKGFWDYF-SQTSGDKGRVEQIHQQKMAREPAGSVRDDLGT 358 A ALL + + ++ F Y S SG V+++H+ PA R Sbjct: 169 AWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCV 228 Query: 359 KEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 418 + + +L A + L ++Q+L+ + + L + +G+E P DP + + Sbjct: 229 QVLSRKLTLKA-------KALHARIQQNLDQLREELSRAFAGTGTEEGAGP-DPQMLSEE 280 Query: 419 LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKP 454 +++ L+ + +A + E ++QQL P Sbjct: 281 VRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAP 316
>gi|114006|sp|P06727|APOA4_HUMAN Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV) Length = 396 Score = 394 bits (1011), Expect = e-110 Identities = 200/202 (99%), Positives = 202/202 (100%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 129 +AEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF Sbjct: 149 QAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 208 Query: 130 KVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA 189 KVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA Sbjct: 209 KVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA 268 Query: 190 PLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 PLAEDVRGNL+GNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK Sbjct: 269 PLAEDVRGNLKGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 328 Query: 250 LGPHAGDVEGHLSFLEKDLRDK 271 LGPHAGDVEGHLSFLEKDLRDK Sbjct: 329 LGPHAGDVEGHLSFLEKDLRDK 350
Score = 110 bits (275), Expect = 2e-24 Identities = 93/348 (26%), Positives = 161/348 (46%), Gaps = 51/348 (14%) Query: 300 AAVLTWALALLSA----FSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDD 355 A VLT AL ++ SA Q WDYFSQ S + A+E Sbjct: 5 AVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNN------------AKEAV------ 46 Query: 356 LGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM 415 E ++ S LT ++ F +D L + +KL P + RL +D + Sbjct: 47 ----EHLQKSELTQQLNALF----QDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKL 98 Query: 416 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR 475 + ++ +ELEE++ARL P+ E + +G NL L+Q+L+PY L QV + ++L+ QL Sbjct: 99 KEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQLT 158 Query: 476 VVGEDTKAQLLGGVDEAWALLQ----GLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQE 531 + + L D A L+ L++++ + K PYA+ I + V+E Sbjct: 159 PYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEE 218 Query: 532 LHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXX 591 L RS+AP+A + +L+ ++ L+ ++ A+ L ARI + ++LR+ L+ Sbjct: 219 LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA---------- 268 Query: 592 XXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAP 639 L+E+VR L+ + +A +DQ+ EE ++++ P Sbjct: 269 -------PLAEDVRGNLKGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 309
Score = 73.9 bits (180), Expect = 2e-13 Identities = 80/404 (19%), Positives = 162/404 (40%), Gaps = 76/404 (18%) Query: 71 AEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK 130 A+Q+ + Y ++ +E + LQ S EL +++ ++ G + YA + + Sbjct: 24 ADQVATVMWDYFSQLSNNAKEAVEHLQKS------ELTQQLNALFQDKLGEVNTYAGDLQ 77 Query: 131 VKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAP 190 K+ EL LA ++ +E++ +LE L ++ +A E+ +I + EL+QRL P Sbjct: 78 KKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEP 137 Query: 191 LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 A+ +R + + Q E+ RR++ PY + + L + + L+ L Sbjct: 138 YADQLRTQV------------------NTQAEQLRRQLTPYAQRMERVLRENADSLQASL 179 Query: 251 GPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALL 310 PHA +++ + ++L+ G L P +V Sbjct: 180 RPHADELKAKIDQNVEELK--------------GRLTPYADEFKVKIDQ----------- 214 Query: 311 SAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAW 370 + + R+ Y T Q+K+ + G L + A L A Sbjct: 215 ---TVEELRRSLAPYAQDT-----------QEKLNHQLEG-----LTFQMKKNAEELKAR 255 Query: 371 ISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARL 430 IS S E+ + E +R L + + L +++EE + R+ Sbjct: 256 ISA--------SAEELRQRLAPLAEDVRGNLKGNTEGLQKSLAELGGHLDQQVEEFRRRV 307 Query: 431 QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQL 474 +PY ++ + +E LRQ+L P+ D+ ++ ++L++++ Sbjct: 308 EPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKV 351
Score = 73.6 bits (179), Expect = 2e-13 Identities = 79/384 (20%), Positives = 149/384 (38%), Gaps = 79/384 (20%) Query: 165 QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF 224 Q+ NA+E + S EL Q+L L +D G + LQK L E Sbjct: 37 QLSNNAKEAVEHLQKS--ELTQQLNALFQDKLGEVNTYAGDLQKKLVPFA-------TEL 87 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVG 284 R+ E + + +++E+LR +L PHA +V + ++L+ + Sbjct: 88 HERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQR------------- 134 Query: 285 GLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKM 344 L P +++Q+ + A Q R+ Y + +++ Sbjct: 135 -LEP--YADQLRTQVNT------------QAEQLRRQLTPYAQR------------MERV 167 Query: 345 AREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSE 404 RE A S++ L P + LK ++Q N+ + +L P + Sbjct: 168 LRENADSLQASLR----------------PHADELKAKIDQ---NVEELKGRLTPYADE- 207 Query: 405 APRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVA 464 + ++ + +EE++ L PY + E + LEGL Q+K +L +++ Sbjct: 208 ----------FKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 257 Query: 465 LRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSG 524 +EL+++L + ED + L G + L L + F+ PY E+ Sbjct: 258 ASAEELRQRLAPLAEDVRGNLKGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKA 317 Query: 525 IGRHVQELHRSVAPHAPASPARLS 548 + + +++L + + PHA LS Sbjct: 318 LVQQMEQLRQKLGPHAGDVEGHLS 341
Score = 45.4 bits (106), Expect = 6e-05 Identities = 33/140 (23%), Positives = 63/140 (45%), Gaps = 7/140 (5%) Query: 23 SADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYA 82 SA+++ + + N K E LQKS L + G G ++ E+ RR++ PY Sbjct: 259 SAEELRQRLAPLAEDVRGNLKGNTEGLQKS-----LAELG--GHLDQQVEEFRRRVEPYG 311 Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 + + L + + L+ L PHA +++ + ++L+ ++ + FK K Q Sbjct: 312 ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLP 371 Query: 143 SLAPYAQDTQEKLNHQLEGL 162 L + QE+ Q++ L Sbjct: 372 ELEQQQEQQQEQQQEQVQML 391
>gi|113992|sp|P02647|APOA1_HUMAN Apolipoprotein A-I precursor (Apo-AI) (ApoA-I) Length = 267 Score = 70.9 bits (172), Expect = 1e-12 Identities = 65/284 (22%), Positives = 127/284 (44%), Gaps = 23/284 (8%) Query: 300 AAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTK 359 AAVLT A+ L+ +QAR FW RV+ + + V D G Sbjct: 3 AAVLTLAVLFLTG---SQARH-FWQQDEPPQSPWDRVKDLATVYV------DVLKDSGRD 52 Query: 360 --EMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRR 417 E S+L +++ L D+ + + +K E+L P++ L ++ G+R+ Sbjct: 53 YVSQFEGSALGKQLNLK----LLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQ 108 Query: 418 QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVV 477 ++ ++LEEVKA++QPY+ + + +E RQ+++P +L E ++ ELQE+L + Sbjct: 109 EMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPL 168 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 537 GE+ + D A A + L++ + ++ ++ E+L G + E H Sbjct: 169 GEEMR-------DRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKAT 221 Query: 538 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELS 581 H + ++ L + L ++ L++ ++L+ Sbjct: 222 EHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLN 265
Score = 70.5 bits (171), Expect = 2e-12 Identities = 53/229 (23%), Positives = 102/229 (44%), Gaps = 17/229 (7%) Query: 25 DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQL--KKTGPSGIKGREAEQLRRQLTPYA 82 D+V + Y L ++ ++ V + S L +QL K +LR QL P Sbjct: 33 DRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVT 92 Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 Q +L + L+ ++ +++EE+K ++ PY D+F+ K + +E R+ Sbjct: 93 QEF-----------WDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 141 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN 202 + P + QE +L L ++ EE++ R A + LR LAP ++++R L Sbjct: 142 KVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAAR 201 Query: 203 TEGLQKS----LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR 247 E L+++ LAE + + + +P E+ + L+ +E + Sbjct: 202 LEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFK 250
Score = 57.0 bits (136), Expect = 2e-08 Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 22/199 (11%) Query: 25 DQVATVMWDYFSQLSNNAKEAVEHLQKSE--LTQQLKKTGPSGIKGREAEQLRRQLTPYA 82 D V + QL +E ++L+K L Q++ K + E+++ ++ PY Sbjct: 75 DSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSK---------DLEEVKAKVQPYL 125 Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 ++ +E + + + P EL+ Q + EL+ +L+P +E + + V+ LR Sbjct: 126 DDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRT 185 Query: 143 SLAPYAQDTQEKLNHQLEGLT-----------FQMKKNAEELKARISASAEELRQRLAPL 191 LAPY+ + +++L +LE L + ++ L + + E+LRQ L P+ Sbjct: 186 HLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPV 245 Query: 192 AEDVRGNLRGNTEGLQKSL 210 E + + E K L Sbjct: 246 LESFKVSFLSALEEYTKKL 264
Score = 51.6 bits (122), Expect = 9e-07 Identities = 31/130 (23%), Positives = 61/130 (46%), Gaps = 7/130 (5%) Query: 133 IDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLA 192 + T +LR L P Q+ + L + EGL +M K+ EE+KA++ ++ +++ Sbjct: 77 VTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEM 136 Query: 193 EDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP 252 E R + ++ AEL Q++ E + ++ P GE ++ LR L P Sbjct: 137 ELYR-------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAP 189 Query: 253 HAGDVEGHLS 262 ++ ++ L+ Sbjct: 190 YSDELRQRLA 199
Score = 50.1 bits (118), Expect = 3e-06 Identities = 31/124 (25%), Positives = 64/124 (51%), Gaps = 9/124 (7%) Query: 137 VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAED 194 V++L +D+ Q EG + N + L ++++ +LR++L P+ ++ Sbjct: 35 VKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQE 94 Query: 195 VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA 254 NL TEGL++ +++ +EE + +V+PY ++F K ++ME RQK+ P Sbjct: 95 FWDNLEKETEGLRQEMSK-------DLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLR 147 Query: 255 GDVE 258 +++ Sbjct: 148 AELQ 151
Score = 43.5 bits (101), Expect = 2e-04 Identities = 25/110 (22%), Positives = 50/110 (45%) Query: 69 REAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADE 128 ++ +L+ +L+P + M R + D+L+ L P++DEL+ ++ +E LK E Sbjct: 156 QKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAE 215 Query: 129 FKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 178 + K + + L P +D ++ L LE EE +++ Sbjct: 216 YHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLN 265
>gi|30580364|sp|Q9BV73|CEP2_HUMAN Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) (C-NAP1) (Centrosome protein 250) (Centrosome associated protein CEP250) Length = 2442 Score = 61.2 bits (147), Expect = 1e-09 Identities = 108/472 (22%), Positives = 195/472 (41%), Gaps = 57/472 (12%) Query: 41 NAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASL 100 +A + +E L++ Q+LK+ +GI L+ QL + ++ R++ D L A Sbjct: 943 DASQQLERLRQDMKVQKLKEQETTGI-------LQTQLQEAQRELKEAARQHRDDLAALQ 995 Query: 101 RPHADELKAKID--QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ 158 + L+ K+D + VE+LK +L D ++ ++Q V+E R Y + Q++L + Sbjct: 996 EESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRL-VEQEVQEKLRETQEYNR-IQKELERE 1053 Query: 159 LEGLTFQMKKNAEELKARISASAEELRQR-LAPLAEDVRGNLRGNTEGLQKSLAELGGHL 217 LT + + +E + + A+ +RQ+ L+ L +D++ +G QK L+ Sbjct: 1054 KASLTLSLME--KEQRLLVLQEADSIRQQELSALRQDMQ-----EAQGEQKELS------ 1100 Query: 218 DQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYEL 277 Q+E R+ V+ +F L Q+ + L + H + + S ++ + + L Sbjct: 1101 -AQMELLRQEVKEKEADF---LAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRL 1156 Query: 278 EDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVE 337 T + +EQ + A L S +SA Q G S + R E Sbjct: 1157 RST---ESQLEALAAEQQPGNQAQA---QAQLASLYSALQQALG--------SVCESRPE 1202 Query: 338 QIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKL 397 A G D G + + + L +S + L QDL + + L Sbjct: 1203 LSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVL 1262 Query: 398 RPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTM 457 R RL D + Q+ EL++++ +L E + W EG + L+ M Sbjct: 1263 RDQVQKLEERL-TDTEAEKSQVHTELQDLQRQLSQNQEEKSK---W--EGKQNSLESELM 1316 Query: 458 DLMEQVA-----LRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVV 504 +L E +A LR ELQ R+ + + L + A ++ LQ+ VV Sbjct: 1317 ELHETMASLQSRLRRAELQ---RMEAQGERELLQAAKENLTAQVEHLQAAVV 1365
Score = 35.0 bits (79), Expect = 0.087 Identities = 50/217 (23%), Positives = 96/217 (44%), Gaps = 24/217 (11%) Query: 43 KEAVEHLQ--KSELTQQL----KKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 +E + LQ K +L QQL +K G + + + EQ ++ Q+++ RE + Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ---EIVVLQQQLQEA-REQGELK 1797 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 + SL+ DE + + Q +EL+ A + + + Q EE + A Q E+ + Sbjct: 1798 EQSLQSQLDEAQRALAQRDQELE------ALQQEQQQAQGQEERVKEKADALQGALEQAH 1851 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH 216 L+ +++ + E+ + A E R+ A E+V G+LR + +K+L L Sbjct: 1852 MTLKERHGELQDHKEQARRLEEELAVEGRRVQA--LEEVLGDLRAESREQEKALLALQQQ 1909 Query: 217 LDQQVEEFRRRVEPYGENFNKALV------QQMEQLR 247 +Q +E +++ +A Q++E LR Sbjct: 1910 CAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALR 1946
Score = 33.9 bits (76), Expect = 0.19 Identities = 55/224 (24%), Positives = 90/224 (40%), Gaps = 31/224 (13%) Query: 422 ELEEVKARLQPYMAEAHELVGWNLEGLRQQ------LKPYTMDLMEQVALRVQELQEQLR 475 EL+E+K +L+ + H VG L Q+ L+ + EQ L+ Q LQ QL Sbjct: 1747 ELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQL- 1805 Query: 476 VVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRH---VQEL 532 D + L D+ LQ Q + R KE A++L + + ++E Sbjct: 1806 ----DEAQRALAQRDQELEALQQEQQQAQGQEERVKEK----ADALQGALEQAHMTLKER 1857 Query: 533 HRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXX 592 H + H + + L +L ++ + + A +++ L LR E SR Sbjct: 1858 HGELQDHKEQA--------RRLEEELAVEGRRVQA-LEEVLGDLRAE-SREQEKALLALQ 1907 Query: 593 XXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQ 636 Q EV R QD++LQ A + DQE E ++ + Sbjct: 1908 QQCAEQAQEHEVETRAL---QDSWLQAQAVLKERDQELEALRAE 1948
>gi|6166599|sp|P35579|MYH9_HUMAN Myosin heavy chain, nonmuscle type A (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) Length = 1960 Score = 59.3 bits (142), Expect = 4e-09 Identities = 130/642 (20%), Positives = 246/642 (38%), Gaps = 143/642 (22%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 129 EAE+LR +LT Q +E + + L+A++++ E + + Sbjct: 898 EAEELRARLTAKKQELEEICHD---------------LEARVEEEEERCQ-----HLQAE 937 Query: 130 KVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA--------EELKARISASA 181 K K+ Q ++EL L + ++KL QLE +T + K E+ +++ Sbjct: 938 KKKMQQNIQELEEQLEE-EESARQKL--QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994 Query: 182 EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQ 241 + L R+A ++ E KSLA+L + + + R+ + Q Sbjct: 995 KLLEDRIAEFTTNLT-----EEEEKSKSLAKLKNKHEAMITDLEERLRR-----EEKQRQ 1044 Query: 242 QMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAA 301 ++E+ R+KL + D+ ++ L+ + + K ++ E++ A++A Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE-------------EELQAALAR 1091 Query: 302 VLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTK-E 360 V A A K + SQ S + E + ++ +R A + DLG + E Sbjct: 1092 VEE------EAAQKNMALKKIRELESQISELQ---EDLESERASRNKAEKQKRDLGEELE 1142 Query: 361 MMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQ 420 ++ S + L+ EQ++N + K LE+ ++ + Q +L Sbjct: 1143 ALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELA 1202 Query: 421 EELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLME----------QVALRVQEL 470 E+LE+ K R++ + +A + LE R +L L++ +V ++QEL Sbjct: 1203 EQLEQTK-RVKANLEKAKQ----TLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257 Query: 471 Q------EQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSG 524 Q E++R D +L +D LL S+ T F L ES + Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL-----ESQLQD 1312 Query: 525 IGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAF 584 +QE +R +KL+L K +++ + RE+L Sbjct: 1313 TQELLQEENR---------------------QKLSLSTKL--KQVEDEKNSFREQLEE-- 1347 Query: 585 XXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAID------QETEEVQQQLA 638 EE + L+ + Q+A + ++ + EEV+++L Sbjct: 1348 ----------------EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ 1391 Query: 639 PPPPG----HSAFAPEFQQTDSGKVLSKLQARLDDLWEDITH 676 G H + + + K ++LQ LDDL D+ H Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLE--KTKTRLQQELDDLLVDLDH 1431
Score = 42.0 bits (97), Expect = 7e-04 Identities = 52/223 (23%), Positives = 102/223 (45%), Gaps = 27/223 (12%) Query: 51 KSELTQQLKKTGPSGIKGREAE--QLRRQLTPYAQRMERVLRENADSLQASL-------- 100 + E+ Q K+ +K EAE QL+ +L A+R +R ++ D L + Sbjct: 1661 REEILAQAKENEKK-LKSMEAEMIQLQEELAA-AERAKRQAQQERDELADEIANSSGKGA 1718 Query: 101 -----RPHADELKAKIDQNVEELKGRLTPYADEFK---VKIDQ--TVEELRRSLAPYAQD 150 + + A++++ +EE +G D K ++IDQ T L RS A ++ Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778 Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL 210 +++L Q + L ++++ +K++ AS L ++A L E + + + K + Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETK-ERQAACKQV 1837 Query: 211 AELGGHLDQ---QVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 L QV++ RR E Y + +KA +++QL+++L Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKAST-RLKQLKRQL 1879
Score = 34.7 bits (78), Expect = 0.11 Identities = 90/445 (20%), Positives = 178/445 (40%), Gaps = 83/445 (18%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 129 E E+L +Q + ME ++ + D + S+ ++ K ++Q VEE+K +L DE Sbjct: 1494 ELERLNKQ---FRTEMEDLM-SSKDDVGKSVH-ELEKSKRALEQQVEEMKTQLEELEDEL 1548 Query: 130 KVKIDQTVE---ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ 186 + D + L+ A + +D Q + + Q E Q+ + E++A + +E +Q Sbjct: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGR-DEQSEEKKKQLVRQVREMEAELE---DERKQ 1604 Query: 187 RLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQL 246 R +A + L+ L +L H+D + NK + ++QL Sbjct: 1605 RSMAVAA---------RKKLEMDLKDLEAHID---------------SANKNRDEAIKQL 1640 Query: 247 RQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGG--LPPPVFSEQVMASMAAVLT 304 R+ L+ ++D EL+DT L +E+ + SM A + Sbjct: 1641 RK---------------LQAQMKD--CMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683 Query: 305 WALALLSAF-----SATQARKGFWDYFSQTSGD-----------KGRVEQIHQQKMAREP 348 L+A A Q R D + +SG + R+ Q+ ++ + Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743 Query: 349 AGSVRDDLGTKEMMEASSLTAWISVPFSRTLK-DSLEQDLNNMNKFLE-KLRPLSGSEAP 406 + +D K ++ + +++ S K ++ Q L NK L+ KL+ + G+ Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803 Query: 407 R-------LPQDPVGMRRQLQEELEEVKARLQPYMAEAHEL--VGWNLEGLRQQLKPYTM 457 + L + QL E +E +A + +L V ++ R+ + Y Sbjct: 1804 KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQY-K 1862 Query: 458 DLMEQVALRVQELQEQLRVVGEDTK 482 D ++ + R+++L+ QL E+ + Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQ 1887
Score = 31.2 bits (69), Expect = 1.3 Identities = 32/155 (20%), Positives = 67/155 (43%), Gaps = 12/155 (7%) Query: 85 MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL---- 140 +ER + ++ + L ELK K+ + +K + + KI Q E+L Sbjct: 1768 LERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNET 1827 Query: 141 --RRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ--RLAPLAEDVR 196 R++ + T++KL L + + ++NAE+ K + ++ L+Q R AE+ Sbjct: 1828 KERQAACKQVRRTEKKLKDVLLQVDDE-RRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886 Query: 197 GNLRGNTEGLQKSL---AELGGHLDQQVEEFRRRV 228 + LQ+ L E ++++V + ++ Sbjct: 1887 QRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 30.8 bits (68), Expect = 1.6 Identities = 34/131 (25%), Positives = 63/131 (48%), Gaps = 11/131 (8%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTP------- 124 E R+QL + ++ L+E ++++ + L+AKI Q E+L Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQ 1836 Query: 125 -YADEFKVK-IDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE 182 E K+K + V++ RR+ Y +D +K + +L+ L Q+++ AEE R +AS Sbjct: 1837 VRRTEKKLKDVLLQVDDERRNAEQY-KDQADKASTRLKQLKRQLEE-AEEEAQRANASRR 1894 Query: 183 ELRQRLAPLAE 193 +L++ L E Sbjct: 1895 KLQRELEDATE 1905
>gi|3043372|sp|P11055|MYH3_HUMAN Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE) Length = 1940 Score = 55.1 bits (131), Expect = 8e-08 Identities = 102/484 (21%), Positives = 198/484 (40%), Gaps = 61/484 (12%) Query: 40 NNAKEAVEHLQK-----SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENAD 94 N K E L ++LT++ K + + + Q + + L + + Sbjct: 974 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE 1033 Query: 95 SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKID----QTVEELRRSLAPYAQD 150 L++SL +L+ +++N +L+G L A E + ++ Q E L++ Y Q Sbjct: 1034 DLESSLEQEK-KLRVDLERNKRKLEGDLK-LAQESILDLENDKQQLDERLKKKDFEYCQL 1091 Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLA--EDVRGNLRGNTEGLQK 208 + + Q GL FQ K +EL+ARI EE+ A A E R + E L + Sbjct: 1092 QSKVEDEQTLGLQFQ--KKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE 1149 Query: 209 SLAELGGHLDQQVEEFRRRVEPY---GENFNKALVQQMEQLRQKLGPHA------GDVEG 259 L E GG Q+E ++R + + +A +Q + HA G+ Sbjct: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQID 1209 Query: 260 HLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQAR 319 +L +++ L +K ++LE + + +SM +V S + + Sbjct: 1210 NLQRVKQKLEKEKSEFKLE-------------IDDLSSSMESVSK------SKANLEKIC 1250 Query: 320 KGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTL 379 + D S+ G +++ + ++ ++++ E S+ + +S Sbjct: 1251 RTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS-----RS 1305 Query: 380 KDSLEQDLNNMNKFLEKLRPLSGSEAPRL--PQDPVGMRRQLQEELEEVKARLQPYMAEA 437 K + Q + + LE+ + A L + + R+ EE +E KA LQ +++A Sbjct: 1306 KQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA 1365 Query: 438 H-ELVGWNLEGLRQQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLLG 487 + E+ W + ++ T +L E ++A R+Q+ +EQ+ V E TK +L G Sbjct: 1366 NSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQG 1424 Query: 488 GVDE 491 V++ Sbjct: 1425 EVED 1428
Score = 40.8 bits (94), Expect = 0.002 Identities = 105/523 (20%), Positives = 203/523 (38%), Gaps = 74/523 (14%) Query: 165 QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF 224 + +K +EL A+ A +EL ++L L ++ + +L+ + ++L + DQ ++ Sbjct: 856 EFQKTKDEL-AKSEAKRKELEEKLVTLVQE-KNDLQLQVQAESENLLDAEERCDQLIKAK 913 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWY---ELEDTC 281 + E +A + E++ +L +E S L+KD+ D + E E Sbjct: 914 FQLEAKIKEVTERA--EDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA 971 Query: 282 PVGGLPPPVFSEQVMASMAAVLTWALALLS-----AFSATQARKGFWDYFSQTSGDKGRV 336 + + A LT L A QA + D + + K ++ Sbjct: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEE---DKVNSLNKTKSKL 1028 Query: 337 EQ-IHQQKMAREPAGSVRDDLG-TKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFL 394 EQ + + + E +R DL K +E A S+ LE D +++ L Sbjct: 1029 EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESIL-------DLENDKQQLDERL 1081 Query: 395 EKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKP 454 +K + + +D + Q Q++++E++AR++ E + + Sbjct: 1082 KK-KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEA---------ERATRA 1131 Query: 455 YTMDLMEQVALRVQELQEQLRVVGEDTKAQL-LGGVDEA--WALLQGLQSRVVHHTGRFK 511 T A ++EL E+L G T Q+ L EA L + L+ + H Sbjct: 1132 KTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVA 1191 Query: 512 ELFHPYAESLVSGIGRHVQELHR--------------------SVAPHAPASPARLSRCV 551 L +A+S V+ +G + L R S S A L + Sbjct: 1192 TLRKKHADS-VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKIC 1250 Query: 552 QVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAF 611 + L +L+ +A+ + IQ++L +L + SR Q + E+ ++L+ Sbjct: 1251 RTLEDQLS-EARGKNEEIQRSLSELTTQKSRL--------------QTEAGELSRQLEE- 1294 Query: 612 RQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQT 654 ++ Q++ +A Q+TEE+++QL +A A Q + Sbjct: 1295 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSS 1337
>gi|114039|sp|P02649|APOE_HUMAN Apolipoprotein E precursor (Apo-E) Length = 317 Score = 54.7 bits (130), Expect = 1e-07 Identities = 52/189 (27%), Positives = 88/189 (46%), Gaps = 21/189 (11%) Query: 28 ATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIK-----GREAEQLRRQLTPYA 82 A ++ + + ++AVE + EL QQ + SG + GR + LR + Sbjct: 6 AALLVTFLAGCQAKVEQAVETEPEPELRQQTE--WQSGQRWELALGRFWDYLR-----WV 58 Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 Q + ++E S Q + EL+A +D+ ++ELK Y E + ++ EE R Sbjct: 59 QTLSEQVQEELLSSQVT-----QELRALMDETMKELKA----YKSELEEQLTPVAEETRA 109 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN 202 L+ Q Q +L +E + ++ + E++A + S EELR RLA +R L + Sbjct: 110 RLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRD 169 Query: 203 TEGLQKSLA 211 + LQK LA Sbjct: 170 ADDLQKRLA 178
Score = 46.6 bits (109), Expect = 3e-05 Identities = 35/158 (22%), Positives = 74/158 (46%), Gaps = 3/158 (1%) Query: 68 GREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYAD 127 G+ E+LR +L + +++ + L +AD LQ L + + ++ + ++ RL P + Sbjct: 145 GQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVE 204 Query: 128 EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK---ARISASAEEL 184 + +V+ + L AQ E+L ++E + + + +E+K A + A EE Sbjct: 205 QGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQ 264 Query: 185 RQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE 222 Q++ AE + L+ E L + + L ++V+ Sbjct: 265 AQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQ 302
Score = 41.6 bits (96), Expect = 0.001 Identities = 40/193 (20%), Positives = 80/193 (41%), Gaps = 17/193 (8%) Query: 450 QQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALL----QGLQSRVVH 505 Q+L+ + M+++ EL+EQL V E+T+A+L + A A L + + R+V Sbjct: 76 QELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQ 135 Query: 506 HTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKAL 565 + G + + +G+ +EL +A H RL R L ++L + Sbjct: 136 YRGEVQAM-----------LGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGA 184 Query: 566 HARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRA 625 ++ L +RE L + + +++R QA+ + ++ Sbjct: 185 REGAERGLSAIRERLGPLVEQGRVRAATV--GSLAGQPLQERAQAWGERLRARMEEMGSR 242 Query: 626 IDQETEEVQQQLA 638 +EV++Q+A Sbjct: 243 TRDRLDEVKEQVA 255
Score = 38.9 bits (89), Expect = 0.006 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 9/132 (6%) Query: 147 YAQDTQEKLNHQL--EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE 204 + Q E++ +L +T +++ +E + A EL ++L P+AE+ R L ++ Sbjct: 57 WVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRARL---SK 113 Query: 205 GLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFL 264 LQ + A LG + E+ R+ Y L Q E+LR +L H + L Sbjct: 114 ELQAAQARLGADM----EDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRD 169 Query: 265 EKDLRDKKFWYE 276 DL+ + Y+ Sbjct: 170 ADDLQKRLAVYQ 181
Score = 32.0 bits (71), Expect = 0.73 Identities = 54/257 (21%), Positives = 98/257 (38%), Gaps = 55/257 (21%) Query: 415 MRRQLQEEL--EEVKARLQPYMAEA-HELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQ 471 + Q+QEEL +V L+ M E EL + E L +QL P + +++ +Q Q Sbjct: 61 LSEQVQEELLSSQVTQELRALMDETMKELKAYKSE-LEEQLTPVAEETRARLSKELQAAQ 119 Query: 472 EQLRVVGEDTKAQLLGGVDEAWALL----QGLQSRVVHHTGRFKELFHPYAESLV----- 522 +L ED +L+ E A+L + L+ R+ H + ++ A+ L Sbjct: 120 ARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAV 179 Query: 523 ------SGIGRHVQELHRSVAPHAPASPAR-----------LSRCVQVLSRKLTLKAKAL 565 G R + + + P R L Q +L + + + Sbjct: 180 YQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEM 239 Query: 566 HARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRA 625 +R + LD+++E+++ EVR +L+ Q LQ AF Sbjct: 240 GSRTRDRLDEVKEQVA---------------------EVRAKLEEQAQQIRLQAEAFQAR 278 Query: 626 I----DQETEEVQQQLA 638 + + E++Q+Q A Sbjct: 279 LKSWFEPLVEDMQRQWA 295
>gi|13431717|sp|Q9UKX3|MYH13_HUMAN Myosin heavy chain, skeletal muscle, extraocular (MyHC-eo) Length = 1938 Score = 51.6 bits (122), Expect = 9e-07 Identities = 106/484 (21%), Positives = 202/484 (41%), Gaps = 66/484 (13%) Query: 41 NAKEAVEHLQK--SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQA 98 N E + L++ S+LT++ K + + + Q+ ++ L + D L+ Sbjct: 981 NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040 Query: 99 SLRPHADELKAKIDQNVEELKGRLTPYAD---EFKVKIDQTVEELRRSLAPYAQDTQEKL 155 SL +L+A +++ +L+G L + + + + Q E+L++ +Q Sbjct: 1041 SLEQEK-KLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARID 1099 Query: 156 NHQLEGLTFQMKKNAEELKARISASAEEL--RQRLAPLAEDVRGNLRGNTEGLQKSLAEL 213 + Q+ L FQ K +EL+ARI EE+ L E R +L E + + L E Sbjct: 1100 DEQVHSLQFQ--KKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157 Query: 214 GGHLDQQVEEFRRRVEPYGE---NFNKALVQQ---MEQLRQK-------LGPHAGDVEGH 260 G Q+E ++R + + + +A +Q LR+K LG +++ Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217 Query: 261 LSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARK 320 LEK+ + K E++D MAS L+ + + + T Sbjct: 1218 KQKLEKEKSELKM--EIDD----------------MASNIEALSKSKSNIERTCRTVE-- 1257 Query: 321 GFWDYFSQTSG-DKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTL 379 D FS+ D+ + + IH M + + +L + + E SL + ++ Sbjct: 1258 ---DQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGEL-SHRVEEKESLISQLT-----KS 1308 Query: 380 KDSLEQDLNNMNKFLEKLRPLSGSEAPRL--PQDPVGMRRQLQEELEEVKARLQPYMAEA 437 K +L Q L + + +E+ + A L + + R+ EE +E KA LQ +++A Sbjct: 1309 KQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKA 1368 Query: 438 H-ELVGWNLEGLRQQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLLG 487 + E+ W + ++ T +L E ++A R+QE +E+ E TK +L G Sbjct: 1369 NSEVAQWKTKYETDAIQ-RTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQG 1427 Query: 488 GVDE 491 V++ Sbjct: 1428 EVED 1431
>gi|13432177|sp|P35749|MYH11_HUMAN Myosin heavy chain, smooth muscle isoform (SMMHC) Length = 1972 Score = 50.8 bits (120), Expect = 2e-06 Identities = 153/737 (20%), Positives = 284/737 (38%), Gaps = 142/737 (19%) Query: 52 SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQ--------------RMERVLRENADSLQ 97 SEL +LKK S +E E+L+R+L A ++ L + + LQ Sbjct: 1037 SELEVRLKKEEKSR---QELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ 1093 Query: 98 ASLRPHADELKAKID--QNVEELKGRLTPY-------------ADEFKVKIDQTVEELRR 142 A+L DE+ K + + + EL+G ++ A++ K + + +E L+ Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153 Query: 143 SLAPYAQDT--QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDV----- 195 L T Q++L + E +KK +E A +E+RQ+ A E++ Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE 1213 Query: 196 -----RGNLRGNTEGLQKSLAELGGHL------DQQVEEFRRRVEPY----------GEN 234 + NL N + L+K A+L G L Q+VE ++++E GE Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273 Query: 235 FNKALVQQMEQLRQKLGPHAG---DVEGHLSFLEKD-------------LRDKKFWYELE 278 L ++ +L+ ++ G + EG L KD L ++ +L Sbjct: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLN 1333 Query: 279 DTCPVGGLPPP--VFSEQVMASMAAV--LTWALALLSAFSATQARKGFWDYFSQT----S 330 + + L +Q+ M A L ++ L+ + ++K D+ S Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN-IQLSDSKKKLQDFASTVEALEE 1392 Query: 331 GDKGRVEQIHQQKMAREPAGSVRDDL-GTKEMMEASSLTAWISVPFSRTLKDSLEQDLNN 389 G K ++I E + D L TK ++ + + R L +LE+ Sbjct: 1393 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRK 1452 Query: 390 MNKFLEKLRPLSG----------SEAPRLPQDPVGMRRQLQEEL---EEVKARLQPYMAE 436 ++ L + + +S +EA + + R L+E L EE++ + AE Sbjct: 1453 FDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAE 1512 Query: 437 AHEL------VGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD 490 +L VG N+ L + + ME++ +++EL+++L+ ED K +L + Sbjct: 1513 MEDLVSSKDDVGKNVHELEKSKRALETQ-MEEMKTQLEELEDELQAT-EDAKLRLEVNMQ 1570 Query: 491 EAWALLQ-GLQSRVVHHTGRFKEL---FHPYAESLVSGIGRHVQELHRSVAPHAPASPAR 546 + LQ+R + + ++L H Y L E R A A+ + Sbjct: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL---------EDERKQRALAAAAKKK 1621 Query: 547 LSRCVQVLSRKLTLKAKALHARIQQ------NLDQLREELSRAFXXXXXXXXXXPDPQML 600 L ++ L + K I+Q + + EL A + + Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681 Query: 601 SEEVRQRLQAFRQDTYLQIAAFTRA---IDQETEEVQQQLAPPPPGHSAFAPEFQQTDSG 657 ++ + L ++D +AA RA D E EE+ ++LA G +A E + Sbjct: 1682 AKSLEADLMQLQED----LAAAERARKQADLEKEELAEELASSLSGRNALQDEKR----- 1732 Query: 658 KVLSKLQARLDDLWEDI 674 +L+AR+ L E++ Sbjct: 1733 ----RLEARIAQLEEEL 1745
Score = 39.7 bits (91), Expect = 0.004 Identities = 119/580 (20%), Positives = 224/580 (38%), Gaps = 81/580 (13%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPY--AQRMERVLRENAD 94 QLS++ K+ + E ++ KK I+ +Q + Y ++ + L++ D Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENL-TQQYEEKAAAYDKLEKTKNRLQQELD 1430 Query: 95 SL------QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA--- 145 L Q L + ++ + K DQ + E K + YADE + E+ ++L+ Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490 Query: 146 --PYAQDTQEKLNHQLEGLTFQMK----------KNAEEL---KARISASAEELRQRLAP 190 A + +E+L + L +M+ KN EL K + EE++ +L Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550 Query: 191 L------AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME 244 L ED + L N + L+ D+Q EE RR+++ + L + + Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610 Query: 245 QLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLT 304 Q + L A LE DL+D EL+ + G + +Q+ A + Sbjct: 1611 Q--RALAAAA------KKKLEGDLKD----LELQADSAIKGREEAI--KQLRKLQAQMKD 1656 Query: 305 WALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIH------QQKMAREPAGSVRDDLGT 358 + L AR + F+ ++ + + + Q+ +A + DL Sbjct: 1657 FQREL------EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEK 1710 Query: 359 KEMME--ASSLTAWISVPFSR--------TLKDSLEQDLNNMNKFLEKLRPLSGSEAPRL 408 +E+ E ASSL+ ++ + L++ LE++ NM +++R + +A +L Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT-QQAEQL 1769 Query: 409 PQDPVGMRRQLQ------EELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQ 462 + R Q ++LE L+ + E V + L+ L EQ Sbjct: 1770 SNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQ 1829 Query: 463 VALRVQELQEQLRVVGEDTK--AQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPY--A 518 V +E Q + + + K ++L V++ + + + + R K+L A Sbjct: 1830 VEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEA 1889 Query: 519 ESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKL 558 E I + ++L R + A S + R V L KL Sbjct: 1890 EEESQRINANRRKLQREL-DEATESNEAMGREVNALKSKL 1928
Score = 32.3 bits (72), Expect = 0.56 Identities = 34/126 (26%), Positives = 67/126 (53%), Gaps = 23/126 (18%) Query: 105 DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK--LNHQLEGL 162 +E++AK D+ +++ K R + K + ++EL + ++Q T+EK L QL+ Sbjct: 852 EEMQAKEDE-LQKTKER--------QQKAENELKELEQK---HSQLTEEKNLLQEQLQAE 899 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPL-----AEDVRGNLRGNTEGLQKSLAELGGHL 217 T ++ AEE++ R++A +EL + L + E+ RG + +K +A+ L Sbjct: 900 T-ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQ---QLQAERKKMAQQMLDL 955 Query: 218 DQQVEE 223 ++Q+EE Sbjct: 956 EEQLEE 961
>gi|50400858|sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen) Length = 2115 Score = 49.7 bits (117), Expect = 3e-06 Identities = 100/468 (21%), Positives = 175/468 (37%), Gaps = 65/468 (13%) Query: 59 KKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEEL 118 +K S ++ +E E+LR + R+ L++ D L+ ++ KI+Q EE Sbjct: 266 EKQAASPLEPKELEELRDKNESLTMRLHETLKQCQD-----LKTEKSQMDRKINQLSEE- 319 Query: 119 KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE-----GLTFQMKKNAEEL 173 G L+ EF + Q + L +++ TQE L Q + Q KK EE Sbjct: 320 NGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEK 379 Query: 174 KARISASAEELRQRLAPLAEDV---RGNLRGNT---EGLQKSLAELGGHLDQQVEEFRRR 227 + +L + L+ L ++ +G + G+ E L++ A L + Q Sbjct: 380 NEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEML 439 Query: 228 VEPYGENFNKALVQQ--MEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGG 285 G+ K L ++ E+ +Q+L D++ +S L + ELE G Sbjct: 440 ETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKE------ELEQASQAHG 493 Query: 286 LPPPVFSEQVMASMAAVLTWALALLSAF---------SATQARKGFWDYFSQTSGDKGRV 336 + + A LT L L+A Q K +QT + + Sbjct: 494 AR--------LTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQA 545 Query: 337 EQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEK 396 Q + ++ + + + + KE+ E T T + E L + L++ Sbjct: 546 SQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQ 605 Query: 397 LRPLSGSEAPRLP----------------QDPVGM----RRQLQEELEEVKARLQPYMAE 436 L L +A +L Q V + +L ++EE++A ++ E Sbjct: 606 LEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665 Query: 437 AHELVGWNLEGLRQQLKPYTMDLMEQ--VALRVQELQEQLRVVGEDTK 482 HE E L QL+ E+ VA +LQEQL+ + E K Sbjct: 666 QHEAQAQVAE-LELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLK 712
Score = 43.5 bits (101), Expect = 2e-04 Identities = 146/715 (20%), Positives = 266/715 (37%), Gaps = 127/715 (17%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 +L+ ++A E + T Q ++ G++ + EQL L ++ E+ L+E A+ Sbjct: 520 ELAGLKQQAKEKQAQLAQTLQQQEQASQGLR-HQVEQLSSSL----KQKEQQLKEVAEKQ 574 Query: 97 QASLRPHADELKAKIDQNVEELKGR----------------------------------- 121 +A+ + HA +L ++ L+ R Sbjct: 575 EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 634 Query: 122 --LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEEL--KARI 177 A K ++ + VEEL ++ A+ Q + Q+ L Q++ ++ K R+ Sbjct: 635 QTSVTQAQREKAELSRKVEEL-QACVETARQEQHEAQAQVAELELQLRSEQQKATEKERV 693 Query: 178 SASAEELRQRLAPLAEDV---RGNLRGN-------TEGLQKSLAELGGHLDQQVEEFRR- 226 + ++L+++L L E + +G+L E Q+ ++EL VE+ +R Sbjct: 694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRE 753 Query: 227 ----RVEPYGENFNKALVQQM--------EQLRQKLGPHAGDVEGHLSFLEKDLRDKKFW 274 E G +A +QQ+ E LR++L S E+ +++ W Sbjct: 754 RKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAW 813 Query: 275 YE-LEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDK 333 E ED+ +F EQ+M L A + + Q S + Sbjct: 814 RERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSEL--QISRQQ 871 Query: 334 GRVEQIH-------QQKMARE-PAGSVRDDLGT-KEMMEASSLTAWISVPFSRTLKDSLE 384 + ++H QQ +E A + DDL T +E M A+S V TL Sbjct: 872 NELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSK----EVARLETLVRKAG 927 Query: 385 QDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWN 444 + ++ L K +G P ++ G + +A LQ EA E +G Sbjct: 928 EQQETASRELVKEPARAGDRQPEWLEEQQG------RQFCSTQAALQAMEREA-EQMGNE 980 Query: 445 LEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEA--WALLQGLQSR 502 LE LR L E+ R Q+ +E R+ E +AQ +++A L LQ+ Sbjct: 981 LERLRAALMESQGQQQEE---RGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNA 1037 Query: 503 VVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKA 562 + F L A +L G+ QEL A+L ++L Sbjct: 1038 LNEQRVEFATLQEALAHALTEKEGKD-QEL------------AKLRGLEAAQIKEL---- 1080 Query: 563 KALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAF 622 ++Q + QL+E+L++ + +E +L+A R A Sbjct: 1081 ----EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALR--------AE 1128 Query: 623 TRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHS 677 ++Q+ ++ Q+Q S A + + L LQ +L++ +++ HS Sbjct: 1129 VSKLEQQCQKQQEQ--ADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHS 1181
Score = 32.0 bits (71), Expect = 0.73 Identities = 45/219 (20%), Positives = 87/219 (39%), Gaps = 16/219 (7%) Query: 418 QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVV 477 QL EE ++ +L+ + + +L L L ++ T + +E+ A +L+++L Sbjct: 315 QLSEENGDLSFKLREFASHLQQLQD-ALNELTEEHSKATQEWLEKQA----QLEKELSAA 369 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 537 +D K ++E +LQG S++ H + ++ P + V G ++ L + A Sbjct: 370 LQDKKC-----LEEKNEILQGKLSQLEEHLSQLQDN-PPQEKGEVLGDVLQLETLKQEAA 423 Query: 538 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDP 597 A + +R + + + +AK L R EE + + Sbjct: 424 TLAANNTQLQARVEMLETERGQQEAKLLAER-----GHFEEEKQQLSSLITDLQSSISNL 478 Query: 598 QMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQ 636 EE+ Q QA Q+A+ T + +QQQ Sbjct: 479 SQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQ 517
Score = 31.2 bits (69), Expect = 1.3 Identities = 96/462 (20%), Positives = 176/462 (38%), Gaps = 54/462 (11%) Query: 36 SQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREA-EQLRRQLTPYAQRMERVLRENAD 94 ++ ++N+ A E + S L ++++ K R A E LR++LT A+R E + Sbjct: 1274 AETASNSARAAE--RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEEL------ 1325 Query: 95 SLQASLRPHADELKA---KIDQNVEELKG-RLTPYADEFKVKIDQTVEELRRSLAPYAQD 150 ELKA K Q + L +L + + V + L + L Sbjct: 1326 ---------GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAA 1376 Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEE------LRQRLAP---LAEDVRGNLRG 201 +++ +LE Q K+ A L+A + + E LRQ++A A+ +R Sbjct: 1377 AEKRHREELE----QSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKAS 1432 Query: 202 NTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL 261 E L L + G L ++ R + L Q E+ Q+L D E L Sbjct: 1433 YAEQL-SMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRL 1491 Query: 262 SFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKG 321 + ++++ + E+ G + Q LT + L F Q ++ Sbjct: 1492 AEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQ- 1550 Query: 322 FWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKD 381 + S+ D + ++ QQK+ A G + EA L A ++ + Sbjct: 1551 -VEELSKKLADSDQASKVQQQKLKAVQA------QGGESQQEAQRLQAQLNE--LQAQLS 1601 Query: 382 SLEQDLNNMNKFLEKLRPLSGSEAPRLP--QDPVGMRRQLQEELEEVKARLQPYMAEAHE 439 EQ + +EK + ++ + Q+ + QLQ+E +E++A + HE Sbjct: 1602 QKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERL---GHE 1658 Query: 440 L--VGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 479 L G + Q + T + + +V +QLR +G+ Sbjct: 1659 LQQAGLKTKEAEQTCRHLTAQ-VRSLEAQVAHADQQLRDLGK 1699
>gi|547966|sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta) Length = 1935 Score = 49.3 bits (116), Expect = 4e-06 Identities = 105/474 (22%), Positives = 195/474 (41%), Gaps = 86/474 (18%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRP--HADELKAKIDQNVEELKGRLTPYADEF 129 +++ +LT + ++ ++ D LQA + K K++Q V++L+G L E Sbjct: 986 DEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE---QEK 1042 Query: 130 KVKIDQTVEELRRSLAPYAQDTQEK------------------------LNHQLE---GL 162 KV++D +E +R L + TQE LN ++E L Sbjct: 1043 KVRMD--LERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQAL 1100 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPLA--EDVRGNLRGNTEGLQKSLAELGGHLDQQ 220 Q++K +EL+ARI EEL A E +R +L E + + L E GG Q Sbjct: 1101 GSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ 1160 Query: 221 VEEFRRRVEPYGE---NFNKALVQQMEQLRQKLGPHA------GDVEGHLSFLEKDLRDK 271 +E ++R + + + +A +Q HA G+ +L +++ L + Sbjct: 1161 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1220 Query: 272 KFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSG 331 K ++LE + V ++M ++ A A L T ++ S+ Sbjct: 1221 KSEFKLE-------------LDDVTSNMEQIIK-AKANLEKMCRT-LEDQMNEHRSKAEE 1265 Query: 332 DKGRVEQIHQQKMAREPA-GSVRDDLGTKEMMEASSLTAWISVPFSRTLKD---SLEQDL 387 + V + Q+ + G + L KE + S LT + +++ L+D LE+++ Sbjct: 1266 TQRSVNDLTSQRAKLQTENGELSRQLDEKEAL-ISQLTRG-KLTYTQQLEDLKRQLEEEV 1323 Query: 388 NNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAH-ELVGWNLE 446 N L+ + + R+ EE E KA LQ +++A+ E+ W + Sbjct: 1324 KAKNALAHALQS---------ARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374 Query: 447 GLRQQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLLGGVDE 491 ++ T +L E ++A R+QE +E + V E TK +L +++ Sbjct: 1375 YETDAIQ-RTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIED 1427
Score = 35.8 bits (81), Expect = 0.051 Identities = 100/509 (19%), Positives = 200/509 (39%), Gaps = 48/509 (9%) Query: 166 MKKNAEELKARISASA---EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE 222 MK+ LK + S +EL +++ L ++ + +L+ + Q +LA+ DQ ++ Sbjct: 852 MKEEFTRLKEALEKSEARRKELEEKMVSLLQE-KNDLQLQVQAEQDNLADAEERCDQLIK 910 Query: 223 EFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCP 282 + ++E + N+ L + E++ +L +E S L++D+ D LE T Sbjct: 911 N-KIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKRDIDD------LELT-- 960 Query: 283 VGGLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGD----KGRV 336 L + + LT +A L A T+ +K + Q D + +V Sbjct: 961 ---LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKV 1017 Query: 337 EQIHQQKMAREPA-----GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMN 391 + + K+ E GS+ + + +E + + ++ LE D ++ Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLD 1077 Query: 392 KFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQ 451 + L+K + R+ +D + QLQ++L+E++AR++ E + Sbjct: 1078 ERLKKKDFELNALNARI-EDEQALGSQLQKKLKELQARIEELEEELES---------ERT 1127 Query: 452 LKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD---EAWALLQGLQSRVVHHTG 508 + L ++ ++E+ E+L G T Q+ E + + L+ + H Sbjct: 1128 ARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1187 Query: 509 RFKELFHPYAESLVSGIGRHVQELHR-SVAPHAPASPARLSRCVQVLSRKLTLKAKALHA 567 L +A+S V+ +G + L R S +L + + +KAKA Sbjct: 1188 TAAALRKKHADS-VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1246 Query: 568 RIQQNL-DQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTR-- 624 ++ + L DQ+ E S+A L E + + + L I+ TR Sbjct: 1247 KMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL-ISQLTRGK 1305 Query: 625 -AIDQETEEVQQQLAPPPPGHSAFAPEFQ 652 Q+ E++++QL +A A Q Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQ 1334
Score = 33.9 bits (76), Expect = 0.19 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 39/204 (19%) Query: 48 HLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL 107 H Q + L Q KK + QL+ ++ Q R E A A+EL Sbjct: 1717 HSQNTSLINQKKKMDA------DLSQLQTEVEEAVQEC-RNAEEKAKKAITDAAMMAEEL 1769 Query: 108 KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK 167 K + D + + + K ++QT+++L+ L D E++ L+G K Sbjct: 1770 KKEQDTSA---------HLERMKKNMEQTIKDLQHRL-----DEAEQI--ALKG----GK 1809 Query: 168 KNAEELKARISASAEELRQRLAPLAEDVRG---------NLRGNTEGLQKSLAELGGHLD 218 K ++L+AR+ EL AE V+G L TE +K+L L +D Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869 Query: 219 Q---QVEEFRRRVEPYGENFNKAL 239 + +V+ ++R+ E E N L Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNL 1893
>gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1) Length = 4684 Score = 49.3 bits (116), Expect = 4e-06 Identities = 116/494 (23%), Positives = 186/494 (37%), Gaps = 63/494 (12%) Query: 44 EAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPH 103 +A QK E ++ ++ G K E +R+L +R L E + + Sbjct: 1796 QAEAEKQKEEAEREARRRG----KAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQE 1851 Query: 104 ADELKAKIDQN------VEELKGRL-------TPYADEFKVKIDQTVEELRRSLAPYAQ- 149 L+A+ +Q +EE RL T E + ++ + E+ LA A+ Sbjct: 1852 LIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAKA 1911 Query: 150 -----DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE 204 T EK +LE + ++ AEE AR+ A AEE + R LAE+ R E Sbjct: 1912 EEESRSTSEKSKQRLEAEAGRFRELAEE-AARLRALAEEAK-RQRQLAEEDAARQRAEAE 1969 Query: 205 G-LQKSLAELG--GHLDQQVEEFRRRVEPYGENFNKALVQ---QMEQLRQKLGPHAGDVE 258 L + LA +G L + E + E E + Q +L ++ H D+E Sbjct: 1970 RVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIE 2029 Query: 259 GHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQA 318 L+ L K ELE GL E + V LAL ++F A Sbjct: 2030 ERLAQLRKASDS-----ELERQ---KGL-----VEDTLRQRRQVEEEILALKASFEKAAA 2076 Query: 319 RKGFWDY----FSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVP 374 K + + D R ++ + + AR+ + ++ +E E + Sbjct: 2077 GKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEE 2136 Query: 375 FSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYM 434 +R K +LE ++ + +E+ R L R Q+ RQLQ E + RLQ Sbjct: 2137 AARQRKAALE-EVERLKAKVEEARSL----RERAEQESA---RQLQLAQEAAQKRLQA-E 2187 Query: 435 AEAHELVGWNLEGLRQQLKPYTMDLME------QVALRVQELQEQLRVVGEDTKAQLLGG 488 +AH E QQ +++ + A R E E+ RV E AQ Sbjct: 2188 EKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQ 2247 Query: 489 VDEAWALLQGLQSR 502 V+EA L Q + + Sbjct: 2248 VEEAERLKQSAEEQ 2261
Score = 43.5 bits (101), Expect = 2e-04 Identities = 92/441 (20%), Positives = 182/441 (41%), Gaps = 65/441 (14%) Query: 25 DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQR 84 D ++ + +L A EA Q+S++ ++L ++ E +L+ ++ A+ Sbjct: 2336 DHQKNLLDEELQRLKAEATEAAR--QRSQVEEELFSVR---VQMEELSKLKARIE--AEN 2388 Query: 85 MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL 144 +LR+ D+ Q L+ A+++K V E RL+ A E ++ Q EE L Sbjct: 2389 RALILRDK-DNTQRFLQEEAEKMK-----QVAEEAARLSVAAQE-AARLRQLAEE---DL 2438 Query: 145 APYAQDTQEKLNHQLEGLTFQMKKNAE-ELKARISASAEELRQRLAPLAEDVRGNLRGNT 203 A ++ L +++ + + AE EL + A+E +RL E + L T Sbjct: 2439 AQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2498 Query: 204 EGLQKSL---------------------AELG---GHLDQQVEEFRRRVEPYGENFNK-- 237 +G Q++L AE+ ++ + FR++ E GE ++ Sbjct: 2499 QGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTE 2558 Query: 238 -------ALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPV 290 LVQ +E RQ+ A + ++ LE++ +K E + V Sbjct: 2559 LATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE--KEKLQQEAKLLQLKSEEMQTV 2616 Query: 291 FSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAG 350 EQ++ A+ + LS + R+ F + +K ++EQ+ Q ++A+ A Sbjct: 2617 QQEQLLQETQAL---QQSFLSEKDSLLQRERFIEQ------EKAKLEQLFQDEVAK--AQ 2665 Query: 351 SVRDD-LGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP 409 +R++ ++ ME S+ +R + E+ + + L++L + L Sbjct: 2666 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLA 2725 Query: 410 QDPVGMRRQLQEELEEVKARL 430 ++ +R QLQ E+ +A L Sbjct: 2726 EENQRLREQLQLLEEQHRAAL 2746
Score = 42.0 bits (97), Expect = 7e-04 Identities = 100/463 (21%), Positives = 190/463 (41%), Gaps = 38/463 (8%) Query: 35 FSQLSNNAKEAVEHLQKSELTQQLKKTG-PSGIKGREAEQLRRQLTPYAQRMERVLRENA 93 F++ + K VE + + L QL++T + E ++L+ + T A++ +V E Sbjct: 2310 FAEQTLRQKAQVEQ-ELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV-EEEL 2367 Query: 94 DSLQASLRPHADELKAKIDQNVEEL----KGRLTPYADEFKVKIDQTVEELRRSLAPYAQ 149 S++ + +LKA+I+ L K + E K+ Q EE R L+ AQ Sbjct: 2368 FSVRVQME-ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR-LSVAAQ 2425 Query: 150 DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL-APLAEDVRGNLRGNTEGLQK 208 + E L Q + LK ++ A E R + A L + + + LQ+ Sbjct: 2426 EAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2485 Query: 209 SLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL 268 ++ L ++ + F+R +E + + L E R KL ++ + E+D Sbjct: 2486 DKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKL--RVAEMSRAQARAEEDA 2540 Query: 269 RDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQ 328 + +F + E+ + + ++ L L + S A + + ++ Sbjct: 2541 Q--RFRKQAEE------IGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAER-LREAIAE 2591 Query: 329 TSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLN 388 +K +++Q + K+ + + +++ T + + T + F KDSL Q Sbjct: 2592 LEREKEKLQQ--EAKLLQLKS----EEMQTVQQEQLLQETQALQQSFLSE-KDSLLQRER 2644 Query: 389 NMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGL 448 + + KL L E + Q +RQ Q+++E+ + RL M EA EG+ Sbjct: 2645 FIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGV 2703 Query: 449 R------QQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQL 485 R QQL+ E +A Q L+EQL+++ E +A L Sbjct: 2704 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAAL 2746
Score = 36.2 bits (82), Expect = 0.039 Identities = 133/619 (21%), Positives = 233/619 (37%), Gaps = 99/619 (15%) Query: 53 ELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR----ENADSLQASLRPHADELK 108 EL ++K + + + A Q +L A+ ER L E A +Q +L + Sbjct: 1653 ELASRVKAEAEAAREKQRALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAE 1712 Query: 109 AKIDQ---NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD--TQEKLNHQLEGLT 163 A++ + E +L E V + Q EE R A+ +E+ QLE Sbjct: 1713 AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQLE--R 1770 Query: 164 FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH-----LD 218 +Q+K N E L+ R+ A E L+Q+ AE + E ++ AE + Sbjct: 1771 WQLKAN-EALRLRLQAE-EVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAE 1828 Query: 219 QQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELE 278 Q++E+ R+ E + + L + E +R + G+ + L LE++L L+ Sbjct: 1829 QELEKQRQLAEGTAQ---QRLAAEQELIRLRAETEQGEQQRQL--LEEELA------RLQ 1877 Query: 279 DTCPVGGLPPPVFSEQVMASMAAVLTWALALLS--AFSATQARKGFWDYFSQTSGDKGRV 336 +++ A +A V LL+ A + ++R + + GR Sbjct: 1878 REAAAATQK----RQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGRF 1933 Query: 337 EQI---------------HQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKD 381 ++ Q+++A E A R + E + A L A + + LK Sbjct: 1934 RELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA---ERVLAEKLAA---IGEATRLKT 1987 Query: 382 SLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELV 441 E L E+LR RL +D RR+L+E+ + KA ++ +A+ + Sbjct: 1988 EAEIALKEKEAENERLR--------RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 2039 Query: 442 GWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQS 501 LE RQ+ L+E + ++++E++ + + G + L G Sbjct: 2040 DSELE--RQK------GLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELEL--GRIR 2089 Query: 502 RVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKL 558 T R K EL L + R +E V A + L Sbjct: 2090 SNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVE 2149 Query: 559 TLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQ 618 LKAK AR + ++ +E +R Q+ E ++RLQA + Sbjct: 2150 RLKAKVEEARSLR--ERAEQESARQL-------------QLAQEAAQKRLQA-------E 2187 Query: 619 IAAFTRAIDQETEEVQQQL 637 A A+ Q+ +E+QQ L Sbjct: 2188 EKAHAFAVQQKEQELQQTL 2206
Score = 33.9 bits (76), Expect = 0.19 Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 33/212 (15%) Query: 69 REAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADE 128 REA++L++++ R E + A + S++ +L+ + ++ K R A+ Sbjct: 1525 REAKELQQRIQEEVVRREEAAVD-AQQQKRSIQEELQQLRQSSEAEIQA-KARQAEAAER 1582 Query: 129 FKVKIDQTVEELRRSLAP---------------------------YAQDTQEKLNHQLEG 161 +++I++ + +R L AQ+ E+L Q++ Sbjct: 1583 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642 Query: 162 LTFQMKKNAE-ELKARISASAEELR--QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLD 218 + Q K+ AE EL +R+ A AE R QR E++R L ++ E + Sbjct: 1643 ES-QRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERWLCQAEVERARQVQ 1701 Query: 219 QQVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 +E +R E ++ + ++ QL + L Sbjct: 1702 VALETAQRSAEAELQSKRASFAEKTAQLERSL 1733
Score = 32.3 bits (72), Expect = 0.56 Identities = 42/232 (18%), Positives = 93/232 (40%), Gaps = 19/232 (8%) Query: 420 QEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 479 Q ELE++ +L+ Y A L W + R+Q + M L + A+R Q QEQ + Sbjct: 1336 QRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEI 1395 Query: 480 DTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQEL 532 + + V+E ++ + ++V + + + + P + V V + Sbjct: 1396 ERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQE 1452 Query: 533 HRSVAPHAPASPARLSRCVQVLSRKLTLK------AKALHARIQQNLDQLREELSRAFXX 586 + + H S+ ++ +S L A+ A ++ L ++ L + Sbjct: 1453 YVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQL 1512 Query: 587 XXXXXXXXPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQETEEVQQ 635 + ++E++QR+Q R++ + R+I +E ++++Q Sbjct: 1513 AEAHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQ 1564
>gi|8134736|sp|P82094|TMF1_HUMAN TATA element modulatory factor (TMF) Length = 1093 Score = 48.5 bits (114), Expect = 8e-06 Identities = 57/254 (22%), Positives = 111/254 (43%), Gaps = 33/254 (12%) Query: 38 LSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR------E 91 + K + + L S + ++L+ K +E E + +L + +E L+ + Sbjct: 559 MEEGEKLSKQQLHNSNIIKKLRA------KDKENENMVAKLNKKVKELEEELQHLKQVLD 612 Query: 92 NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVK---IDQTVEELRRSLAPYA 148 + ++ R + +L + +++ ++L GRL DE + K I ++ + L Sbjct: 613 GKEEVEKQHRENIKKLNSMVERQEKDL-GRLQVDMDELEEKNRSIQAALDSAYKELTDLH 671 Query: 149 QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 + K + E + K EEL A + + EE RQ+ LA V G+LR + ++ Sbjct: 672 KANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQV-GDLRLALQRTEQ 730 Query: 209 SLAELGGHLDQQVEEFRRRVEPYGENFN-----------KALVQQMEQLRQKLGPHAGDV 257 + A +L ++ E ++R++ EN N + L++Q+E L+ LG Sbjct: 731 AAARKEDYLRHEIGELQQRLQE-AENRNQELSQSVSSTTRPLLRQIENLQATLGSQTSSW 789 Query: 258 EGHLSFLEKDLRDK 271 E LEK+L D+ Sbjct: 790 EK----LEKNLSDR 799
>gi|1346640|sp|P35580|MYH10_HUMAN Myosin heavy chain, nonmuscle type B (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B) Length = 1976 Score = 48.5 bits (114), Expect = 8e-06 Identities = 148/719 (20%), Positives = 269/719 (37%), Gaps = 135/719 (18%) Query: 52 SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI 111 S+L ++LKK E+ R++L ++++ + D + A L+ DELK ++ Sbjct: 1037 SDLEERLKKE----------EKTRQELEKAKRKLDGETTDLQDQI-AELQAQIDELKLQL 1085 Query: 112 DQNVEELKGRLTPYADE--FKVKIDQTVEELRRSLAPYAQDTQEK-------------LN 156 + EEL+G L DE K + V EL+ +A +D + + L+ Sbjct: 1086 AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLS 1145 Query: 157 HQLEGL------------------------TFQMKKNAEELKARISASAEELRQRLAPLA 192 +LE L ++KK EE A +++RQR A Sbjct: 1146 EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATAL 1205 Query: 193 EDV----------RGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQ 242 E++ + NL N +GL+ EL + + ++V+ E+ K L Q Sbjct: 1206 EELSEQLEQAKRFKANLEKNKQGLETDNKELACEV-----KVLQQVKAESEHKRKKLDAQ 1260 Query: 243 MEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELED--TCPVGGLPPPVFSEQVMASMA 300 +++L HA EG +E + K EL++ T + + AS+ Sbjct: 1261 VQEL------HAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLE 1314 Query: 301 AVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRV-EQIHQQKMAR------------- 346 + L LL T+ + Q +K + EQ +++ AR Sbjct: 1315 SQLQDTQELLQ--EETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQ 1372 Query: 347 --EPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSE 404 + V DDLGT E +E + + + L LE+ +K LEK + E Sbjct: 1373 LADTKKKVDDDLGTIESLEEAKKKL---LKDAEALSQRLEEKALAYDK-LEKTKNRLQQE 1428 Query: 405 APRLPQDPVGMRRQLQEELEEVKARLQPYMAE--------AHELVGWNLEGLRQQLKPYT 456 L D + +RQ+ LE+ + + +AE A E E ++ K + Sbjct: 1429 LDDLTVD-LDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS 1487 Query: 457 MDLMEQVALRVQE----LQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKE 512 + + AL +E +QLR ED L+ D+ + VH + K Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMED----LMSSKDDV--------GKNVHELEKSKR 1535 Query: 513 LFHPYAESLVSGIGRHVQELHRS------VAPHAPASPARLSRCVQVLSRKLTLKAKALH 566 E + + + EL + + + A A+ R +Q + K + L Sbjct: 1536 ALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLI 1595 Query: 567 ARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAI 626 ++++ +L +E + D + L ++ +A R + Q+ R + Sbjct: 1596 KQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKA-RDEVIKQL----RKL 1650 Query: 627 DQETEEVQQQLAPPPPGH-SAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGHS 684 + ++ Q++L FA Q +S K L L+A + L E++ S + H+ Sbjct: 1651 QAQMKDYQRELEEARASRDEIFA---QSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
Score = 38.9 bits (89), Expect = 0.006 Identities = 120/604 (19%), Positives = 229/604 (37%), Gaps = 123/604 (20%) Query: 36 SQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERV------L 89 SQL++ K+ + L E ++ KK ++AE L ++L A +++ L Sbjct: 1371 SQLADTKKKVDDDLGTIESLEEAKKK-----LLKDAEALSQRLEEKALAYDKLEKTKNRL 1425 Query: 90 RENADSL------QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS 143 ++ D L Q + + ++ + K DQ + E K YA+E + E+ ++ Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485 Query: 144 LA-----PYAQDTQEKLNHQLEGLTFQMK----------KNAEEL---KARISASAEELR 185 L+ A + +E+ Q + L M+ KN EL K + EE+R Sbjct: 1486 LSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMR 1545 Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 245 +L L ++++ TE + L + Q E + + E + L++Q+ + Sbjct: 1546 TQLEELEDELQA-----TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600 Query: 246 LRQKLGPHAGD---VEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAV 302 L +L +E DL+D LE +Q+ A + Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKD------LEAQIEAANKARDEVIKQLRKLQAQM 1654 Query: 303 LTWALALLSAFSATQARKGFWDYFSQTSGDKGRV-----------EQIHQQKMAREPAGS 351 + L +AR + F+Q+ + ++ E++ + AR A Sbjct: 1655 KDYQREL------EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQ 1708 Query: 352 VRDDLGTKEMMEASSLTAWISVPFS-----RTLKDSLEQDLNNMNKFLEKLRP------- 399 RD+L + AS +A + L++ LE++ +NM ++ R Sbjct: 1709 ERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDT 1768 Query: 400 ----LSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPY 455 L+ + D R+QL+ + +E+KA+LQ LEG + Sbjct: 1769 LNAELAAERSAAQKSD--NARQQLERQNKELKAKLQ------------ELEGAVKSKFKA 1814 Query: 456 TMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHT-GRFKELF 514 T+ +E ++ +L+EQL ++ A +++V T + KE+F Sbjct: 1815 TISALE---AKIGQLEEQLEQEAKERAA----------------ANKLVRRTEKKLKEIF 1855 Query: 515 HPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLD 574 V RH + ++ A A +L R ++ + T +A A ++Q+ LD Sbjct: 1856 -----MQVEDERRHADQ-YKEQMEKANARMKQLKRQLEEAEEEAT-RANASRRKLQRELD 1908 Query: 575 QLRE 578 E Sbjct: 1909 DATE 1912
Score = 38.1 bits (87), Expect = 0.010 Identities = 38/158 (24%), Positives = 75/158 (47%), Gaps = 19/158 (12%) Query: 69 REAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELK--------- 119 ++++ R+QL + ++ L+E ++++ + L+AKI Q E+L+ Sbjct: 1781 QKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAA 1840 Query: 120 GRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISA 179 +L ++ +I VE+ RR Y ++ EK N +++ L Q+++ AEE R +A Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQY-KEQMEKANARMKQLKRQLEE-AEEEATRANA 1898 Query: 180 SAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL 217 S +L++ L E EGL + ++ L L Sbjct: 1899 SRRKLQRELDDATE--------ANEGLSREVSTLKNRL 1928
Score = 35.4 bits (80), Expect = 0.066 Identities = 135/637 (21%), Positives = 244/637 (38%), Gaps = 115/637 (18%) Query: 105 DELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK--LNHQLEGL 162 +EL+AK D+ + ++K + T K++ +EE+ R + Q +EK L QL+ Sbjct: 852 EELQAK-DEELLKVKEKQT--------KVEGELEEMERK---HQQLLEEKNILAEQLQAE 899 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE 222 T ++ AEE++AR++A +EL + L L V N + LQ ++ H+ Q +E Sbjct: 900 T-ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERN-QILQNEKKKMQAHI-QDLE 956 Query: 223 EFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL-----RDKKFWYE- 276 E + + E RQKL E + +E+++ ++ KF E Sbjct: 957 E---------------QLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK 1001 Query: 277 --LEDTCPVGGLPPPVFSEQVMA-SMAAVLTWALALLSAF---------SATQARKGFWD 324 +ED + + E+ A ++A + ++S + + K Sbjct: 1002 KLMEDR--IAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059 Query: 325 YFSQTSGDKGRVEQIHQQ---------KMAREPAGSV-RDDLGTKEMMEASSLTAWISVP 374 +T+ + ++ ++ Q K E G++ R D T A + + Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQ 1119 Query: 375 FSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYM 434 + L++ E + + NK ++ R LS ++ ++ +L++ L+ A+ Q Sbjct: 1120 IAE-LQEDFESEKASRNKAEKQKRDLS--------EELEALKTELEDTLDTTAAQ-QELR 1169 Query: 435 AEAHELVGWNLEGLRQQLKPY---TMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDE 491 + + V + L ++ K + D+ ++ A ++EL EQL + KA L Sbjct: 1170 TKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLE-QAKRFKANLEKN--- 1225 Query: 492 AWALLQGLQSRVVHHTGRFKELFHPYAES--LVSGIGRHVQELHRSV----------APH 539 QGL++ K L AES + VQELH V A Sbjct: 1226 ----KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281 Query: 540 APASPARLSRCVQVLSR------KLTLKAKALHARIQQNLDQLREE------LSRAFXXX 587 A L +L K A +L +++Q + L+EE LS Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL 1341 Query: 588 XXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAID------QETEEVQQQLAPPP 641 + Q EE R+ L+ Q+A + +D + EE +++L Sbjct: 1342 EEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA 1401 Query: 642 PGHSAFAPE--FQQTDSGKVLSKLQARLDDLWEDITH 676 S E K ++LQ LDDL D+ H Sbjct: 1402 EALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDH 1438
Score = 32.0 bits (71), Expect = 0.73 Identities = 33/157 (21%), Positives = 65/157 (41%), Gaps = 10/157 (6%) Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 ER + +D+ + L ELKAK+ + +K + + KI Q E+L + Sbjct: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835 Query: 146 PYAQDTQ--EKLNHQLEGLTFQM---KKNAEELKARISASAEELRQRLAPLAEDVRGNLR 200 A + + +L+ + Q+ +++A++ K ++ + ++Q L E R Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATR 1895 Query: 201 GNT--EGLQKSL---AELGGHLDQQVEEFRRRVEPYG 232 N LQ+ L E L ++V + R+ G Sbjct: 1896 ANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGG 1932
>gi|12643718|sp|Q13439|GOA4_HUMAN Golgi autoantigen, golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (72.1 protein) Length = 2230 Score = 48.5 bits (114), Expect = 8e-06 Identities = 133/686 (19%), Positives = 270/686 (39%), Gaps = 70/686 (10%) Query: 37 QLSNNAKEAVEHLQKSELT--QQLKKTGPSGIKGREAEQ-LRRQLTPYAQRMERVLRENA 93 Q++ +E E +KSE ++L+K + K EA + L+ ++ + +E+ E Sbjct: 393 QMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 452 Query: 94 DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE 153 SLQ L E+ + ++ EE +L ++ + +Q EL + L ++ QE Sbjct: 453 ISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ---ELTKKLQTREREFQE 509 Query: 154 KLNHQLEGLTFQMKKNAEELKARISASAEEL---RQRLAPLAEDVRGNLRGNTEGLQKSL 210 ++ LE + K ++E + + S + EEL ++ + +E+ +L+ E + + Sbjct: 510 QMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569 Query: 211 AELGGHLDQQVEEFRRR-------VEPYGENFNKALVQQMEQLRQKLG--PHAGDV---- 257 EL L++ ++E + + +E NK + +E+ + +L H D Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTE 629 Query: 258 ------EGHLSFLEKDLRDKKFWYE---LEDTCPVGGLPPPVFSEQVMASMAAVLTWALA 308 + + + +EK LR+K + L+D + +E+ + + T + Sbjct: 630 KLQVLKQQYQTEMEK-LREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELES 688 Query: 309 LLSAFS-ATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSL 367 L S S +AR + S +++Q + KM D+ + S+ Sbjct: 689 LSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM---------DEQKNHHQQQVDSI 739 Query: 368 TAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVK 427 V RT K +L+ +N + L++ + ++R + EL++ Sbjct: 740 IKEHEVSIQRTEK-ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRS-EGELQQAS 797 Query: 428 ARL---QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQ 484 A+L Q Y + HE E L QL+ +DL + L +++ E + +D + Sbjct: 798 AKLDVFQSYQSATHEQTKAYEEQL-AQLQQKLLDLETERILLTKQVAE-VEAQKKDVCTE 855 Query: 485 LLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASP 544 L + L+Q L+ + + K L Y L G Q V Sbjct: 856 LDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQ 915 Query: 545 AR--LSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSE 602 R + +++L++KL+ K ++H L EE F + + E Sbjct: 916 MREGQKKEIEILTQKLSAKEDSIHI--------LNEEYETKF----------KNQEKKME 957 Query: 603 EVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSK 662 +V+Q+ + ++ ++ + +E E +L+ +A E Q +S + S Sbjct: 958 KVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI-SD 1016 Query: 663 LQARLDDLWEDITHSLHDQGHSHLGD 688 +RL+ ++ SL + L D Sbjct: 1017 AVSRLETNQKEQIESLTEVHRRELND 1042
Score = 40.4 bits (93), Expect = 0.002 Identities = 100/498 (20%), Positives = 200/498 (40%), Gaps = 70/498 (14%) Query: 41 NAKEAVEH---LQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRME-RVLRENADSL 96 N ++ +EH +QK + Q+L + + +K E + L + Y+ + E ++ + + Sbjct: 1552 NQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHV 1611 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 S++ +ELKA D+ E +L E K K +Q + +++ L Sbjct: 1612 NLSVKSKEEELKALEDRLESESAAKLA----ELKRKAEQKIAAIKKQLLS---------- 1657 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL--QKSLAELG 214 Q+E Q KK E + ++ +E + + L E ++ +E L +S + Sbjct: 1658 -QMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVA 1716 Query: 215 GHLDQQVEEFRRRVEPYGENFNKAL---VQQMEQLRQKLGPH-----AGDVEGHLSFLEK 266 + +Q+ + + V+ E L + + E+L Q++G + E + E+ Sbjct: 1717 AYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQER 1776 Query: 267 DLR-DKKFWYELEDTCPVGGLPPPVFSEQVMASM-AAVLTWALALLSAFSATQARKGFWD 324 ++ + + ED +G L + + S+ A + A Q + +D Sbjct: 1777 LIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFD 1836 Query: 325 YFSQTSGDKGRVEQIHQQKMAREPAGSVR---------DDLGTK---------------- 359 +T +K QI +QK+ + VR ++L +K Sbjct: 1837 DVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKP 1896 Query: 360 -EMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFL---EKLRPLSGSEAPRLPQDPVGM 415 E++E ++ S L ++E N++ L E+ + G E RL +D + Sbjct: 1897 TELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML 1956 Query: 416 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGL----RQQLKPYTMDLMEQVALRVQELQ 471 R++ Q+ELE +K + Y E E + E L LK + Q+A + QEL+ Sbjct: 1957 RKEHQQELEILK---KEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2013 Query: 472 EQLRVV---GEDTKAQLL 486 ++ ++ +A+LL Sbjct: 2014 MTIKETINKAQEVEAELL 2031
Score = 34.3 bits (77), Expect = 0.15 Identities = 139/714 (19%), Positives = 263/714 (36%), Gaps = 108/714 (15%) Query: 36 SQLSNNAKEAVEHLQ--KSELTQQLKKTGPSGIKGRE-AEQLRRQLTPYAQRMERVLREN 92 S+L++ K E Q KS + K ++ ++ +E+L QL ++ E +L Sbjct: 1172 SELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAK 1231 Query: 93 ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ 152 + L + + ++I + R T + +K TV EL L ++ Q Sbjct: 1232 TNELINISSSKTNAILSRISH----CQHRTTKVKEALLIKTC-TVSELEAQLRQLTEE-Q 1285 Query: 153 EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE 212 LN + T Q+++ ++K+ + A E L L ++ GN + + + + Sbjct: 1286 NTLNISFQQATHQLEEKENQIKS-MKADIESLVTEKEALQKE-GGNQQQAASEKESCITQ 1343 Query: 213 LGGHLDQQVEEFRRRVEPYGE------NFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK 266 L L + + E E + +K L QL+ + + E +S L K Sbjct: 1344 LKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRK 1401 Query: 267 DLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQAR------- 319 ++K EL D S++ ++++ V W+ Q+R Sbjct: 1402 QYDEEKC--ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNT 1459 Query: 320 ------------KGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSL 367 K ++ Q + K ++Q Q K G + DD E E S+L Sbjct: 1460 VKELQIQLELKSKEAYEKDEQINLLKEELDQ--QNKRFDCLKGEMEDDKSKMEKKE-SNL 1516 Query: 368 TAWISVPFSRTLK------------DSLEQDLNNMNK--------FLEKLRPLS--GSEA 405 + +R ++ +SL + L N N+ ++KL+ G E Sbjct: 1517 ETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEK 1576 Query: 406 PRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVAL 465 ++ L+ ++ +KA L+ E E V +++ ++LK L + A Sbjct: 1577 DNRVKEAEEKILTLENQVYSMKAELETKKKEL-EHVNLSVKSKEEELKALEDRLESESAA 1635 Query: 466 RVQELQEQLRVVGEDTKAQLLGGVDEAWALLQ-GLQSRVVHHTGRFKEL---FHPYAESL 521 ++ EL+ + K QLL ++E + G +S + + +E H E L Sbjct: 1636 KLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL 1695 Query: 522 VSGIGRHVQEL-----HRSVAPHAPASPARLSRCVQ--------VLSRKLTLKAKALHAR 568 S + L ++VA + A CVQ VL R LT K K L Sbjct: 1696 KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLL--- 1752 Query: 569 IQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQ 628 Q + Q +EE +S R Q + L+ A + DQ Sbjct: 1753 --QRVGQEKEET-------------------VSSHFEMRCQYQERLIKLEHAEAKQHEDQ 1791 Query: 629 ET-EEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQ 681 +Q++L +S + + + GK + + L+++++D+ +L ++ Sbjct: 1792 SMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEK 1845
Score = 30.0 bits (66), Expect = 2.8 Identities = 46/257 (17%), Positives = 107/257 (41%), Gaps = 45/257 (17%) Query: 38 LSNNAKEAVEHLQKSELT-----QQLKKTGPSGIKGREAEQLR-RQLTPYAQRME----- 86 L N + + LQ+ ELT Q++K+ ++ +E ++ +LT ++++ Sbjct: 1831 LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM 1890 Query: 87 -------RVLRENADS----------LQASLRPHADELKAKI---DQNVEELKGRLTPYA 126 +L EN + L +++ ++L+ K+ ++ ++L + Sbjct: 1891 DGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1950 Query: 127 DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ----MKKNAEELKARISASAE 182 + ++ + +EL Y Q+ +EK+ + E L + +K+ E +++ + Sbjct: 1951 KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQ 2010 Query: 183 ELRQRLAPL---AEDVRGNL----RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF 235 EL + A++V L + T L K +AE L + + + ++ E Sbjct: 2011 ELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2070 Query: 236 N---KALVQQMEQLRQK 249 + L Q+E+L++K Sbjct: 2071 TAKVRDLQTQLEELQKK 2087
Score = 30.0 bits (66), Expect = 2.8 Identities = 51/266 (19%), Positives = 110/266 (41%), Gaps = 31/266 (11%) Query: 372 SVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQ 431 SV TL+ +++ N + + E ++ + L + ++ QL E L+E++ Sbjct: 277 SVKTLETLQQRVKRQENLLKRCKETIQSHK-EQCTLLTSEKEALQEQLDERLQELEKIKD 335 Query: 432 PYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDE 491 +MAE +L+ QL+ +L+EQ L++ +V +TK Q+ ++ Sbjct: 336 LHMAEKTKLI--------TQLRD-AKNLIEQ-------LEQDKGMVIAETKRQMHETLEM 379 Query: 492 AWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCV 551 + L+SR+ T + +EL +S + +EL ++++ AR Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQKEKSERAAF----EELEKALSTAQKTEEAR----- 430 Query: 552 QVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAF 611 + L ++ + K + ++ L++ELSR + Q+ + + Sbjct: 431 RKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELA 490 Query: 612 RQDTYLQIAAFTRAIDQETEEVQQQL 637 R++ L T+ + E Q+Q+ Sbjct: 491 RKEQEL-----TKKLQTREREFQEQM 511
>gi|27923755|sp|Q9P2M7|CING_HUMAN Cingulin Length = 1197 Score = 47.8 bits (112), Expect = 1e-05 Identities = 129/589 (21%), Positives = 232/589 (39%), Gaps = 87/589 (14%) Query: 119 KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 178 +G LT +E + K+D+ V++ R+ L P + +L + E + ++++ E K Sbjct: 355 QGELTRKVEELQRKLDEEVKK-RQKLEPSQVGLERQLEEKTEECS-RLQELLERRKGEAQ 412 Query: 179 ASAEELR--QRLAPLAEDVRGNLRGNTEGLQKSLAELGGH------LDQQVEEFRRRVEP 230 S +EL+ +RL ED+R L LQ L + G L + + E R +E Sbjct: 413 QSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEE 472 Query: 231 YGENFNKALVQQMEQLRQK-LGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPP 289 E K V++ +LR++ L G ++ ++ ++++ + Y+ + + Sbjct: 473 VLEG--KQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDA 530 Query: 290 VFSEQVM-ASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRV--EQIHQQKMAR 346 V+ A + L T G W Q + + R +++ Q +M + Sbjct: 531 TQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEK 590 Query: 347 EPAGSVRDDLGTK-EMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEA 405 E + ++LG K E+++ A S +R + + L+++L + L++L +A Sbjct: 591 E---EMEEELGEKIEVLQRELEQARASAGDTRQV-EVLKKELLRTQEELKEL------QA 640 Query: 406 PRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLME---- 461 R Q+ G R ELE+ A L+ EL NL+ L++ L+ D E Sbjct: 641 ERQSQEVAGRHRD--RELEKQLAVLRVEADRGRELEEQNLQ-LQKTLQQLRQDCEEASKA 697 Query: 462 -QVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAES 520 VA + Q R E T + DE + GL+ ++ G Sbjct: 698 KMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRG------------ 745 Query: 521 LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRK---LTLKAKALHARIQQ------ 571 LV G G V+ R A +L + + L +AL AR+++ Sbjct: 746 LVDG-GEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLA 804 Query: 572 NLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETE 631 L Q ++ L+RA L EE +QR R L+ R +D+ + Sbjct: 805 RLGQEQQTLNRA----------------LEEEGKQREVLRRGKAELEEQK--RLLDRTVD 846 Query: 632 EVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHD 680 + ++L E DS + L +LQA+L+D E + D Sbjct: 847 RLNKEL------------EKIGEDSKQALQQLQAQLEDYKEKARREVAD 883
Score = 40.8 bits (94), Expect = 0.002 Identities = 107/505 (21%), Positives = 199/505 (39%), Gaps = 93/505 (18%) Query: 44 EAVEHL--QKSELTQQLKKTGPSGIKGREAEQLRRQ-LTPYAQRMERVLRENADSL---Q 97 + VEH+ Q T+QL+++ + + RQ ++ + ++R L E ++ Q Sbjct: 507 QEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQ 566 Query: 98 ASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ----- 152 + + + ++L+A Q + +L+ +E KI+ EL ++ A Q Sbjct: 567 SMFQKNKEDLRAT-KQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLK 625 Query: 153 -EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL-AEDVRGN-LRGNTEGLQKS 209 E L Q E Q ++ ++E+ R EL ++LA L E RG L LQK+ Sbjct: 626 KELLRTQEELKELQAERQSQEVAGR--HRDRELEKQLAVLRVEADRGRELEEQNLQLQKT 683 Query: 210 LAELG--------------------GHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 L +L G VE R + + F + ++ +QL++ Sbjct: 684 LQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKET 743 Query: 250 LGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALAL 309 G G +E LRDK E E +Q+ ++ A +L Sbjct: 744 RGLVDGG-----EAVEARLRDKLQRLEAE-------------KQQLEEALNASQEEEGSL 785 Query: 310 LSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQ-KMAREPAGSVRDDL--GTKEMMEASS 366 +A A +AR + R+ Q Q A E G R+ L G E+ E Sbjct: 786 AAAKRALEAR------LEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKR 839 Query: 367 LTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEV 426 L L++ ++ +NK LEK+ S +L + + + E+ + Sbjct: 840 L---------------LDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADA 884 Query: 427 KARLQPYMAEAHELVGW------NLEGLRQQLKPYTMDL------MEQVALRVQELQEQL 474 + + + + +EA + G ++ LRQ L+ + E +A R+Q L+++ Sbjct: 885 QRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEA 944 Query: 475 --RVVGEDTKAQLLGGVDEAWALLQ 497 + +D +A+ L G++E + L+ Sbjct: 945 ENKKRSQDDRARQLKGLEEKVSRLE 969
Score = 36.2 bits (82), Expect = 0.039 Identities = 71/293 (24%), Positives = 124/293 (42%), Gaps = 51/293 (17%) Query: 24 ADQVATVMWDYFSQLSNNAKEAVEHLQKSE-----LTQQLKKTGPSGIKGREAEQLRRQL 78 A+ ATV+ + + +E E + L QQLK+T + G EA + R L Sbjct: 701 AEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGL-VDGGEAVEAR--L 757 Query: 79 TPYAQRMERVLRENADSLQASLRPHADELKAK--IDQNVEELKGRLTPYADEFKVKIDQT 136 QR+E ++ ++L AS AK ++ +EE + L E + +++ Sbjct: 758 RDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQT-LNRA 816 Query: 137 VEE-------LRRSLAPYAQD------TQEKLNHQLEGLTFQMKKNAEELKARISASAEE 183 +EE LRR A + T ++LN +LE + K+ ++L+A++ E+ Sbjct: 817 LEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEK 876 Query: 184 LRQRLAPL----------AEDVRGNL-------RGNTEGLQKSLAELG-GHLDQQVEEFR 225 R+ +A AE G L + + LQ S AE LD+++ R Sbjct: 877 ARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQR 936 Query: 226 -RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYEL 277 + +E EN ++ + QL+ +E +S LE +L ++K EL Sbjct: 937 LQGLEQEAENKKRSQDDRARQLK--------GLEEKVSRLETELDEEKNTVEL 981
Score = 30.0 bits (66), Expect = 2.8 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 10/119 (8%) Query: 73 QLRRQLTPYAQRMERVLRENA--DSLQASLRPHADELKAKID---QNVEELKGRLTPYAD 127 QL Q +R++ RE S L EL +I+ Q+V + K +L+ Sbjct: 1043 QLESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVK 1102 Query: 128 EFKVKIDQTVEELRR--SLAPYAQ---DTQEKLNHQLEGLTFQMKKNAEELKARISASA 181 K ++D+ EE+ R L AQ + Q ++N QL+ ++K++ +R +A + Sbjct: 1103 ALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAES 1161
>gi|13638390|sp|P12882|MYH1_HUMAN Myosin heavy chain, skeletal muscle, adult 1 (Myosin heavy chain IIx/d) (MyHC-IIx/d) Length = 1939 Score = 47.4 bits (111), Expect = 2e-05 Identities = 101/471 (21%), Positives = 195/471 (41%), Gaps = 90/471 (19%) Query: 77 QLTPYAQRMERVLRENADSLQASLRPHADELKAKI--DQNVEELKGRLTPYADEFKVKID 134 +LT + ++ ++ D LQA KAKI +Q V++L+G L E K+++D Sbjct: 995 KLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE---QEKKIRMD 1051 Query: 135 QTVEELRRSL----------APYAQDTQEKLNHQL-----------------EGLTFQMK 167 +E +R L A ++ +++L+ +L + L Q++ Sbjct: 1052 --LERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQ 1109 Query: 168 KNAEELKARISASAEELRQRLA--PLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR 225 K +EL+ARI EE+ A AE R +L E + + L E GG Q+E + Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169 Query: 226 RRVEPYGE---NFNKALVQQ---MEQLRQK-------LGPHAGDVEGHLSFLEKDLRDKK 272 +R + + + +A +Q LR+K LG +++ LEK+ + K Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1229 Query: 273 FWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGD 332 E++D +AS ++ A L + D S+ Sbjct: 1230 M--EIDD----------------LASNMETVSKAKGNLEKMC-----RALEDQLSEIKTK 1266 Query: 333 KGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNK 392 + +++ A+ ++++ E +L + +S K + Q + + + Sbjct: 1267 EEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLS-----RGKQAFTQQIEELKR 1321 Query: 393 FL-EKLRPLSG-SEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAH-ELVGWNLEGLR 449 L E+++ S + A + + + R+ EE +E KA LQ M++A+ E+ W + Sbjct: 1322 QLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYET 1381 Query: 450 QQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLLGGVDE 491 ++ T +L E ++A R+Q+ +E + V E TK +L V++ Sbjct: 1382 DAIQ-RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVED 1431
Score = 44.7 bits (104), Expect = 1e-04 Identities = 101/518 (19%), Positives = 209/518 (40%), Gaps = 50/518 (9%) Query: 158 QLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL 217 ++ + + +K EEL A+ A +EL +++ L ++ + +L+ + SLA+ Sbjct: 852 EMANMKEEFEKTKEEL-AKTEAKRKELEEKMVTLMQE-KNDLQLQVQAEADSLADAEERC 909 Query: 218 DQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYEL 277 DQ ++ + E +A + E++ +L +E S L+KD+ D L Sbjct: 910 DQLIKTKIQLEAKIKEVTERA--EDEEEINAELTAKKRKLEDECSELKKDIDD------L 961 Query: 278 EDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGD--- 332 E T L + + LT +A L A T+ +K + QT D Sbjct: 962 ELT-----LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQA 1016 Query: 333 -KGRVEQIHQQKMAREPA-----GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQD 386 + +V + + K+ E GS+ + + +E + + ++ +E D Sbjct: 1017 EEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIEND 1076 Query: 387 LNNMNKFLEKLR-PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNL 445 +++ L+K +SG ++ + +GM QLQ++++E++AR++ E Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSKIEDEQALGM--QLQKKIKELQARIEELEEEIEAERASRA 1134 Query: 446 EGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD---EAWALLQGLQSR 502 + +Q+ ++ ++E+ E+L G T AQ+ E + + L+ Sbjct: 1135 KAEKQR---------SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185 Query: 503 VVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKA 562 + H L +A+S V+ +G + L R V + + + L+ + + Sbjct: 1186 TLQHEATAATLRKKHADS-VAELGEQIDNLQR-VKQKLEKEKSEMKMEIDDLASNMETVS 1243 Query: 563 KALHARIQQNLDQLREELSRAFXXXXXXXXXXPD-----PQMLSEEVRQRLQAFRQDTYL 617 KA +++ L ++LS D ++ +E Q +DT + Sbjct: 1244 KA-KGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLV 1302 Query: 618 -QIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQT 654 Q++ +A Q+ EE+++QL SA A Q + Sbjct: 1303 SQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
Score = 30.8 bits (68), Expect = 1.6 Identities = 40/165 (24%), Positives = 72/165 (43%), Gaps = 15/165 (9%) Query: 42 AKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLR 101 A+E + S +++KK +K L+ +L Q + ++ L+A +R Sbjct: 1770 AEELKKEQDTSAHLERMKKNLEQTVK-----DLQHRLDEAEQLALKGGKKQIQKLEARVR 1824 Query: 102 PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG 161 E++++ +NVE +KG L + + K QT E+ + L QD +KL +++ Sbjct: 1825 ELEGEVESEQKRNVEAVKG-LRKHERKVKELTYQTEEDRKNILR--LQDLVDKLQAKVKS 1881 Query: 162 LTFQMKKNAEELKA------RISASAEELRQRLAPLAEDVRGNLR 200 Q ++ E+ RI EE +R A +AE LR Sbjct: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEER-ADIAESQVNKLR 1925
Score = 30.0 bits (66), Expect = 2.8 Identities = 46/224 (20%), Positives = 97/224 (43%), Gaps = 26/224 (11%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKG--REAEQLRRQLTPYAQRMERVLRENAD 94 QL++ + A E L+ TQ + K + R E L+ QL +R A+ Sbjct: 1632 QLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERR--------AN 1683 Query: 95 SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK 154 LQA + +EL+A ++Q K A++ + + V+ L +T++K Sbjct: 1684 LLQAEI----EELRATLEQTERSRK-----IAEQELLDASERVQLLHTQNTSLI-NTKKK 1733 Query: 155 LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELG 214 L + + +M+ +E + A++ A +AE+++ + L + Sbjct: 1734 LETDISQIQGEMEDIIQEAR-NAEEKAKKAITDAAMMAEELK-----KEQDTSAHLERMK 1787 Query: 215 GHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE 258 +L+Q V++ + R++ + K +Q+++L ++ G+VE Sbjct: 1788 KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1831
>gi|28201804|sp|Q14789|GOGB1_HUMAN Golgi autoantigen, golgin subfamily B member 1 (Giantin) (Macrogolgin) (Golgi complex-associated protein, 372-kDa) (GCP372) Length = 3259 Score = 47.0 bits (110), Expect = 2e-05 Identities = 128/692 (18%), Positives = 268/692 (38%), Gaps = 97/692 (14%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR-- 90 +Y ++ KE EL + LK+ K +E +QL++ Y +++ + R Sbjct: 1989 EYLEKIQGAQKEPGNKSHAKELQELLKE------KQQEVKQLQKDCIRYQEKISALERTV 2042 Query: 91 ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD 150 + + +Q + + K + Q VE K A FKV +D T E R LA + Sbjct: 2043 KALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS-FKVLLDDTQSEAARVLADNLK- 2100 Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL 210 +++L E + QMK+ E+L+ R+ AEE + ++ LR L++++ Sbjct: 2101 LKKELQSNKESVKSQMKQKDEDLERRLE-QAEEKHLKEKKNMQEKLDALRREKVHLEETI 2159 Query: 211 AELGGHLDQQVEEFRRRVEPYGENFNKALVQ---------QMEQLRQKLGPHAGDVEGHL 261 E+ L+++ +E V+ EN + + Q ++ R ++ A E Sbjct: 2160 GEIQVTLNKKDKE----VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2215 Query: 262 S----FLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQ 317 S E+++R K ED C V + + + L S + Sbjct: 2216 SDAIQSKEEEIRLK------EDNCSV-----------LKDQLRQMSIHMEELKINISRLE 2258 Query: 318 ARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSR 377 K W+ K + E QQK+ G ++ L E ++ + Sbjct: 2259 HDKQIWE-------SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLE 2311 Query: 378 TLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMR------RQLQEELE---EVKA 428 + SL+ L +++ LEK + G+ + Q ++ QL+ +L+ E+ + Sbjct: 2312 SELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTS 2371 Query: 429 RLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQEL------QEQLRVVGEDTK 482 RL + + + L G + ++ +L +Q ++EL +E+ +V E+ Sbjct: 2372 RLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEEN 2431 Query: 483 AQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYA-----ESLVSGIGRHVQELHRSV- 536 + + ++ L+ ++ + + + + G + ++E H S+ Sbjct: 2432 KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII 2491 Query: 537 ------APHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXX 590 A A +L ++ L + + +A++ L Q RE+L++ Sbjct: 2492 LEKDQLIQEAAAENNKLKEEIRGLRSHMD-DLNSENAKLDAELIQYREDLNQVI-----T 2545 Query: 591 XXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPE 650 Q+L +++Q + ++ Y ++ + E+EE + L S A + Sbjct: 2546 IKDSQQKQLLEVQLQQNKEL--ENKYAKLEEKLK----ESEEANEDLR-----RSFNALQ 2594 Query: 651 FQQTDSGKVLSKLQARLDDLWEDITHSLHDQG 682 ++ D K + L+ + L +T +L ++G Sbjct: 2595 EEKQDLSKEIESLKVSISQLTRQVT-ALQEEG 2625
Score = 43.9 bits (102), Expect = 2e-04 Identities = 117/578 (20%), Positives = 221/578 (38%), Gaps = 57/578 (9%) Query: 32 WDYFSQLSNNAKEAVEH---LQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERV 88 +D S +KE ++H L K E Q+ +K + I R++L R+E Sbjct: 963 YDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALIN-------RKELLQRVSRLEEE 1015 Query: 89 LRENADSLQASLRPHADELKAKIDQ---NVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 L D + + P ++ + ++++ N E + +T E ++ + QT+ E L Sbjct: 1016 LANLKDESKKEI-PLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQ 1074 Query: 146 PYAQDTQEKL--NHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL---R 200 +D +EKL Q + L QM + ++ +I E+ + A + + + N Sbjct: 1075 HIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASD 1134 Query: 201 GNTEGLQKSLAEL-------GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPH 253 G++ L K + H ++EE +E E K L Q+ R+ + Sbjct: 1135 GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKL-QEALTSRKAILKK 1193 Query: 254 AGDVEGHLSFLEKDLRDKKFWY-ELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSA 312 A + E H L ++L+ +K Y L++ F EQ + + Sbjct: 1194 AQEKERH---LREELKQQKDDYNRLQEQ----------FDEQSKENENIGDQLRQLQIQV 1240 Query: 313 FSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDL---GTKEMMEASSLTA 369 + + D S G E + + + +L +AS+L Sbjct: 1241 RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQG 1300 Query: 370 WISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE-LEEVKA 428 SV + +E + LE + SE + ++ ++ Q+ ++ LE Sbjct: 1301 GTSVAQIKAQLKEIEAE----KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESL 1356 Query: 429 RLQPYMAEAH-ELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLG 487 + + AE H E + LE QL+ ++ + ++ ++ ELQ+ + ED + L G Sbjct: 1357 KTVSHEAEVHAESLQQKLES--SQLQIAGLEHLRELQPKLDELQKLISKKEEDV-SYLSG 1413 Query: 488 GVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA--PHAPASPA 545 + E A L +Q+ ++ K L H E +++L + P Sbjct: 1414 QLSEKEAALTKIQTEIIEQEDLIKAL-HTQLEMQAKEHDERIKQLQVELCEMKQKPEEIG 1472 Query: 546 RLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRA 583 SR Q + RKL + +++N L+EELS A Sbjct: 1473 EESRAKQQIQRKLQAALISRKEALKEN-KSLQEELSLA 1509
Score = 39.7 bits (91), Expect = 0.004 Identities = 92/486 (18%), Positives = 201/486 (41%), Gaps = 68/486 (13%) Query: 26 QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRM 85 Q+ V +L N + E L++SE + + + ++ E + L +++ + Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ-EEKQDLSKEIESLKVSI 2611 Query: 86 ERVLRE-NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL---R 141 ++ R+ A + +L + +LK K EE RL+ + +I + EEL + Sbjct: 2612 SQLTRQVTALQEEGTLGLYHAQLKVK-----EEEVHRLSALFSSSQKRIAELEEELVCVQ 2666 Query: 142 RSLAPYAQDTQEKLNHQLE------GLTFQMKKNAEELKARISASAEELRQRLAPLAEDV 195 + A + ++KL +L+ G+ + AEE A ++ E+ Q+L + ++ Sbjct: 2667 KEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKEN 2726 Query: 196 RGNLRGNTEGLQKSLAELGG---HLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP 252 +G L + +S++ L H +++++E +R+ + A ++++ QL++ Sbjct: 2727 KG-LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYD--------ASLKELAQLKE---- 2773 Query: 253 HAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSA 312 +G L+ E+D + + + T ++Q+++ +L + L + Sbjct: 2774 -----QGLLN-RERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2827 Query: 313 FSATQA-----------RKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEM 361 ++ Q+ R W+ +K R + +Q+ A +P+ S + K+ Sbjct: 2828 YNQVQSFSKAMASLQNERDHLWNEL-----EKFRKSEEGKQRSAAQPSTSPAEVQSLKKA 2882 Query: 362 MEASSLTAWISVPFSRTLKD--SLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQL 419 M + + R LK+ +L+Q +N+ + +L PL QD + + Sbjct: 2883 MSS------LQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEY--QDKTKAFQIM 2934 Query: 420 QEELEEVKARLQPYMAEAH-ELVGWNLEGLRQQLKPYTMDL--MEQVALRVQELQEQLRV 476 QEEL + Q + + E W + R+ + Y M + +Q +Q L +LR Sbjct: 2935 QEELRQENLSWQHELHQLRMEKSSWEIHE-RRMKEQYLMAISDKDQQLSHLQNLIRELRS 2993 Query: 477 VGEDTK 482 T+ Sbjct: 2994 SSSQTQ 2999
Score = 36.6 bits (83), Expect = 0.030 Identities = 111/637 (17%), Positives = 255/637 (40%), Gaps = 99/637 (15%) Query: 30 VMWDYFSQLSNNAKEAVEHL------QKSELTQQLKKTGPSGIKG--------REAEQLR 75 ++ + +SN A E ++H+ +K EL +L+ T + + +E E+++ Sbjct: 1617 ILLQSYENVSNEA-ERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK 1675 Query: 76 RQLTPYAQRMERV---LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF-KV 131 ++ +A+ ++ L E D L+A + P D K + +E L +E +V Sbjct: 1676 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAK----ECMETLLSSNASMKEELERV 1731 Query: 132 KID-QTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAP 190 K++ +T+ + +SL ++ L+ +++ L Q++ N + + + A E Sbjct: 1732 KMEYETLSKKFQSL----MSEKDSLSEEVQDLKHQIEDNVSK---QANLEATEKHDNQTN 1784 Query: 191 LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKA-----LVQQMEQ 245 + E+ ++ G TE + V + ++F+ +QQ++Q Sbjct: 1785 VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1844 Query: 246 LRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTW 305 L++++ E+ ++K+F LE+ + + S + Sbjct: 1845 LKERIA----------GLEEEKQKNKEFSQTLEN------------EKNTLLSQISTKDG 1882 Query: 306 ALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEAS 365 L +L + ++ E++ + +E A +DDL + M + + Sbjct: 1883 ELKMLQE-----------EVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLA 1931 Query: 366 SLTAWIS-----VPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQ 420 L I V ++ + LE ++ N+ K + +L E +L ++ + +++ Sbjct: 1932 ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE----EEKQQLVKEKTKVESEIR 1987 Query: 421 EE-LEEVK-ARLQP----YMAEAHELVGWNLEGLRQQLKPYT-----MDLMEQVALRVQE 469 +E LE+++ A+ +P + E EL+ + ++Q K + +E+ ++ Sbjct: 1988 KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF 2047 Query: 470 LQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHV 529 +Q + + E TK L V+ L S V E A++L Sbjct: 2048 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL-------- 2099 Query: 530 QELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXX 589 +L + + + + +++ + + L R+L +A+ H + ++N+ + + L R Sbjct: 2100 -KLKKELQSNKESVKSQMKQKDEDLERRLE-QAEEKHLKEKKNMQEKLDALRREKVHLEE 2157 Query: 590 XXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAI 626 ++ Q+LQ T Q+AAFT+++ Sbjct: 2158 TIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSM 2194
Score = 35.8 bits (81), Expect = 0.051 Identities = 127/669 (18%), Positives = 257/669 (38%), Gaps = 111/669 (16%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 129 E L R L Q E + E A+ ++ I VEEL L+ E Sbjct: 828 EQSTLIRSLQSQLQNKESEVLEGAERVR------------HISSKVEELSQALSQKELEI 875 Query: 130 KVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEEL---------------- 173 K+DQ + E +R + Q +EK + Q+ ++F M + +L Sbjct: 876 -TKMDQLLLEKKRDVETLQQTIEEK-DQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKE 933 Query: 174 KARISASAEELRQRLAPLAEDVRGNLRGNTEGL----QKSLAELGGHLD---QQVEEFRR 226 + + + AEE ++ +V L+ N + + Q S EL D ++ E+ +R Sbjct: 934 QLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKR 993 Query: 227 RVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKD---LRDKKFWYELEDTCPV 283 +++ N K L+Q++ +L ++L + + + E + + + K E + C Sbjct: 994 KLQAALIN-RKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVT 1052 Query: 284 GGLPP-PVFSEQVMASMAAVLTWALA-LLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQ 341 ++ +Q ++ L L +A + + +QT DK + Q Sbjct: 1053 SKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQ 1112 Query: 342 QKMAREPAGSVRDDLGTKEMMEASSL-----TAWISVPF---SRTLKDSLEQDLNNMNKF 393 +++ A + + + S+ T IS P S K LE+ + + K Sbjct: 1113 AEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKE 1172 Query: 394 LEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLK 453 E QLQ++L+E + + +A E E L+QQ Sbjct: 1173 KE----------------------QLQKKLQEALTSRKAILKKAQEKERHLREELKQQKD 1210 Query: 454 PYT--MDLMEQVALRVQELQEQLRVVGEDTKAQLLGGV-----DEAWALLQGLQSRVV-- 504 Y + ++ + + + +QLR + + + G + E+ + GL+ + Sbjct: 1211 DYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKA 1270 Query: 505 ---HHTGRFKEL-------FHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVL 554 HHT E H S + G G V ++ ++ A L V Sbjct: 1271 TEQHHTQPVLESNLCPDWPSHSEDASALQG-GTSVAQI-KAQLKEIEAEKVELELKVSST 1328 Query: 555 SRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQD 614 + +LT K+ + + QL+E++++ + ++ +E ++Q+L++ Sbjct: 1329 TSELTKKS--------EEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES---- 1376 Query: 615 TYLQIAAF--TRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWE 672 + LQIA R + + +E+Q+ ++ S + + + ++ L+K+Q + + E Sbjct: 1377 SQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEA--ALTKIQTEIIE-QE 1433 Query: 673 DITHSLHDQ 681 D+ +LH Q Sbjct: 1434 DLIKALHTQ 1442
Score = 35.8 bits (81), Expect = 0.051 Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 33/216 (15%) Query: 377 RTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRR------QLQEELEEVKARL 430 + LK + L ++NK++E+++ G+ P PQ + + + + E+E++K +L Sbjct: 94 KKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKL 153 Query: 431 QPYMAEAHELVGW---NLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLG 487 Q E EL+ L + + + ME+ + Q+LQE+ + +AQL Sbjct: 154 Q----EKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFI-STLQAQLSQ 208 Query: 488 GVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARL 547 E Q Q V RF+ + + L+ + + E + Sbjct: 209 TQAE-----QAAQQVVREKDARFETQVRLHEDELLQLVTQADVE-------------TEM 250 Query: 548 SRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRA 583 + ++VL RKL ++L R Q +D L++EL+ A Sbjct: 251 QQKLRVLQRKLEEHEESLVGRAQV-VDLLQQELTAA 285
Score = 35.0 bits (79), Expect = 0.087 Identities = 60/246 (24%), Positives = 96/246 (39%), Gaps = 53/246 (21%) Query: 23 SADQVATVMWDYFSQLSNNAKEAVE-HLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPY 81 SA Q T + +QL E VE L+ S T +L K K E QL+ Q+ Sbjct: 1296 SALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTK------KSEEVFQLQEQINKQ 1349 Query: 82 AQRMERV------LRENADSLQASLRP---------HADELKAKIDQ------------- 113 +E + +A+SLQ L H EL+ K+D+ Sbjct: 1350 GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS 1409 Query: 114 ----NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN 169 + E + LT E ++ + ++ L L A++ E++ QL+ +MK+ Sbjct: 1410 YLSGQLSEKEAALTKIQTEI-IEQEDLIKALHTQLEMQAKEHDERIK-QLQVELCEMKQK 1467 Query: 170 AEELKARISASAEELRQRLAPLA---EDVRGN---------LRGNTEGLQKSLAELGGHL 217 EE+ A + R+ A L E ++ N RG E L KSLA++ + Sbjct: 1468 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1527 Query: 218 DQQVEE 223 Q +E Sbjct: 1528 SAQNKE 1533
Score = 33.5 bits (75), Expect = 0.25 Identities = 72/422 (17%), Positives = 177/422 (41%), Gaps = 56/422 (13%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQ---ASLRPHADELKAKI---DQNVEELKGRLTPY 125 ++L+++ Q E V E A+ +Q ++R EL K+ + N +E + +L Sbjct: 1609 KELQKEYEILLQSYENVSNE-AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ-- 1665 Query: 126 ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR 185 + +Q +EE++ + +A+ Q+K+ ++++ + L+A + + + + Sbjct: 1666 ------EAEQEMEEMKEKMRKFAKSKQQKI--------LELEEENDRLRAEVHPAGDTAK 1711 Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 245 + ++L + +++E + E + F ++L+ + + Sbjct: 1712 E-------------------CMETLLSSNASMKEELERVKMEYETLSKKF-QSLMSEKDS 1751 Query: 246 LRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTW 305 L +++ +E ++S +K + T P EQ SM+ T Sbjct: 1752 LSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC 1811 Query: 306 ALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEAS 365 + ++ SA SA A + + + +++Q+ ++ E + E + Sbjct: 1812 SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1871 Query: 366 SLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEE 425 +L + IS L++++ MN ++++ E R+ + ++ +EE ++ Sbjct: 1872 TLLSQISTKDGEL--KMLQEEVTKMNLLNQQIQ----EELSRVTK----LKETAEEEKDD 1921 Query: 426 VKARLQPYMAEAHELVGWNLEGLRQ-QLKPYTMDL-MEQVALRVQELQEQ-LRVVGEDTK 482 ++ RL +AE + +G + + Q+K ++ M+ + V EL+E+ ++V E TK Sbjct: 1922 LEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTK 1981 Query: 483 AQ 484 + Sbjct: 1982 VE 1983
Score = 31.2 bits (69), Expect = 1.3 Identities = 61/271 (22%), Positives = 110/271 (40%), Gaps = 69/271 (25%) Query: 46 VEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD 105 +E +KSE +Q PS E + L++ ++ +R+L+E + Q L+ Sbjct: 2852 LEKFRKSEEGKQRSAAQPS-TSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ---- 2906 Query: 106 ELKAKIDQNVEEL---KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL 162 I+Q + EL K +L Y D K K Q ++E R QE L+ Q E Sbjct: 2907 -----INQEITELHPLKAQLQEYQD--KTKAFQIMQEELR---------QENLSWQHELH 2950 Query: 163 TFQMKKNAEELKAR---------ISASAEELRQRLAPLAEDVRGN--------------- 198 +M+K++ E+ R IS ++L L L ++R + Sbjct: 2951 QLRMEKSSWEIHERRMKEQYLMAISDKDQQL-SHLQNLIRELRSSSSQTQPLKVQYQRQA 3009 Query: 199 ---LRGNTEGLQKSLAE---LGGHLDQQVEEFRR---RVEPYGENFNKALVQQ------- 242 + +G Q + E L L+ ++E + R++ NF++ L ++ Sbjct: 3010 SPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQL 3069 Query: 243 ---MEQLRQKLGPHAGDVEGHLSFLEKDLRD 270 + LR+ H GD+ H + LEK +++ Sbjct: 3070 CDTSQSLRENQ-QHYGDLLNHCAVLEKQVQE 3099
Score = 29.6 bits (65), Expect = 3.6 Identities = 58/265 (21%), Positives = 108/265 (40%), Gaps = 51/265 (19%) Query: 43 KEAVEHLQKSELTQ-QLKKTGPSGIKGREAEQLRRQL----------------TPYAQRM 85 KE + +++LTQ Q ++ S + E +++QL T Q Sbjct: 156 KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAA 215 Query: 86 ERVLRENADSLQASLRPHADEL---------KAKIDQNVEELKGRLTPYADEFKVKIDQT 136 ++V+RE + +R H DEL + ++ Q + L+ +L + +E V Q Sbjct: 216 QQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH-EESLVGRAQV 274 Query: 137 VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVR 196 V+ L++ L A+ + L+ QL+ QM+ L+ + EE + L + +V Sbjct: 275 VDLLQQELTA-AEQRNQILSQQLQ----QMEAEHNTLRNTVETEREESKILLEKMELEV- 328 Query: 197 GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGD 256 + + LQ+ + L +E+F + + E L + L QK H + Sbjct: 329 AERKLSFHNLQEEMHHL-------LEQFEQAGQAQAE-----LESRYSALEQK---HKAE 373 Query: 257 VEGHLSFLEKDLRDKKFWYELEDTC 281 +E S + L +K EL+ C Sbjct: 374 MEEKTSHI---LSLQKTGQELQSAC 395
Score = 28.9 bits (63), Expect = 6.2 Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 18/111 (16%) Query: 103 HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL 162 H DEL+ ++ + EL+ + ++ +D+ +E+ LN +E Sbjct: 682 HQDELE-RLKSQILELELNFHKAQEIYEKNLDEKAKEI------------SNLNQLIE-- 726 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPLAE-DVRGNLRGNTEGLQKSLAE 212 + KKNA+ + +A +EE Q L+ + E + LR + L+ +LAE Sbjct: 727 --EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAE 775
Score = 28.5 bits (62), Expect = 8.1 Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 15/221 (6%) Query: 39 SNNAKEAVEHLQK--SELTQQLKKTGPSGIKGREAEQLRRQLT----PYAQRMERVLREN 92 +N KE + L+ +L + K I+ RE L + +T Q +E L++N Sbjct: 2505 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE--DLNQVITIKDSQQKQLLEVQLQQN 2562 Query: 93 ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQ 152 + L+ ++LK + N E+L+ +E K + + +E L+ S++ + Sbjct: 2563 KE-LENKYAKLEEKLKESEEAN-EDLRRSFNALQEE-KQDLSKEIESLKVSISQLTRQVT 2619 Query: 153 EKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAED---VRGNLRGNTEGLQKS 209 GL K EE R+SA ++R+A L E+ V+ ++ Sbjct: 2620 ALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDK 2679 Query: 210 LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 L + HL R E E + L + + ++ QKL Sbjct: 2680 LKKELKHLHHDAGIMRNETETAEERVAE-LARDLVEMEQKL 2719
Score = 28.5 bits (62), Expect = 8.1 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 10/123 (8%) Query: 70 EAEQLRRQLTPYAQRMERVLREN---ADSLQASLRPHADELKAKIDQNVEELKGR----- 121 E + + RQ Q+ + L+E AD+ L+ HA +++ +EE+K + Sbjct: 63 ELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVL 122 Query: 122 -LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISAS 180 P ++E K D++ E + QEK + L Q+ + E A+ S Sbjct: 123 PTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEK-EELISTLQAQLTQAQAEQPAQSSTE 181 Query: 181 AEE 183 EE Sbjct: 182 MEE 184
>gi|266902|sp|P30622|REST_HUMAN Restin (Cytoplasmic linker protein-170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament associated protein) Length = 1427 Score = 46.2 bits (108), Expect = 4e-05 Identities = 46/201 (22%), Positives = 101/201 (50%), Gaps = 18/201 (8%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMER----VLRENADSLQA 98 KE ++ S+L + + K RE ++ QL +++E +++ + D+ + Sbjct: 873 KEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDN-SS 931 Query: 99 SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL-------RRSLAPYAQDT 151 L DEL+ K +++VEEL+ +LT A+E + +++E++ ++ A ++ Sbjct: 932 QLTKMNDELRLK-ERDVEELQLKLTK-ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 989 Query: 152 QEKLNHQLEGLTFQMKKN---AEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 +++L +L L +M+ + +ELKAR + E + + + ++++ L +TE K Sbjct: 990 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLL-DTEDKLK 1048 Query: 209 SLAELGGHLDQQVEEFRRRVE 229 E L Q++EE R++ + Sbjct: 1049 GAREENSGLLQELEELRKQAD 1069
Score = 35.8 bits (81), Expect = 0.051 Identities = 62/270 (22%), Positives = 108/270 (40%), Gaps = 48/270 (17%) Query: 42 AKEAVEHLQKS--ELTQQLKKTGPSGIKGREAE--QLRRQLTPYAQRME---------RV 88 A E LQKS ++T + +++ K E E +L R+L+ ++ME + Sbjct: 957 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 1016 Query: 89 LRENADS------------LQASLRPHADELKAKIDQN------VEEL-----KGRLTPY 125 E A S LQ +L D+LK ++N +EEL K + Sbjct: 1017 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1076 Query: 126 ADEFKVKIDQTVEELRRSLAPY--AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEE 183 A++ ++Q +E +LA + T KL ++L+ L KN EEL Sbjct: 1077 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNK-------- 1128 Query: 184 LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALV-QQ 242 + L + R E L+++ A+ L EE + E G + ++ Q+ Sbjct: 1129 -SKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 1187 Query: 243 MEQLRQKLGPHAGDVEGHLSFLEKDLRDKK 272 +E+ R L +++ S KD ++K Sbjct: 1188 LEEERSVLNNQLLEMKKRESKFIKDADEEK 1217
>gi|50403702|sp|O95613|PCNT2_HUMAN Pericentrin 2 (Pericentrin B) (Kendrin) Length = 3336 Score = 45.8 bits (107), Expect = 5e-05 Identities = 92/449 (20%), Positives = 171/449 (38%), Gaps = 48/449 (10%) Query: 66 IKGREAEQLRRQLTP-YAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTP 124 + G E E LR L+ + ++E + +L + L ++ Q + L+ R Sbjct: 242 VHGLELEALRLSLSNMHTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQH 301 Query: 125 YADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL 184 + + + + EE+ A + +EKL ++E +K E+ ++ E L Sbjct: 302 ELELLREQHAREKEEVVLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENL 361 Query: 185 RQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME 244 R+ L+ + +L+ QK LAE L++ ++ + + E N +E Sbjct: 362 RKELSAKHQSEMEDLQNQ---FQKELAEQRAELEKIFQD-KNQAERALRNLESHHQAAIE 417 Query: 245 QLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLT 304 +LR+ L G L F K+ +K +LE E + AS Sbjct: 418 KLREDLQSEHGRCLEDLEFKFKESEKEK---QLE-------------LENLQASYED--- 458 Query: 305 WALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEA 364 L A S + R+ W + + ++H+Q +AR + L +E + Sbjct: 459 -----LKAQSQEEIRR-LWSQLDSARTSRQELSELHEQLLARTSRVEDLEQLKQREKTQH 512 Query: 365 SSLTAWISVPFSRTLKD---SLEQDLNNMNKFLEKLRPLS-------GSEAPRLPQDPVG 414 S + + F + L+D + ++DL + + L+ R + G L + P Sbjct: 513 ESELEQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGAREDALLDSVEVGLSCVGLEEKPEK 572 Query: 415 MRRQLQEEL--EEVKARLQPYMAEAHELVGWNLEGLRQQL-KPYTMDLMEQVALRVQELQ 471 R+ +EL E K L + AE E LE L L + + ++ + L Sbjct: 573 GRKDHVDELEPERHKESLPRFQAELEESHRHQLEALESPLCIQHEGHVSDRCCVETSALG 632 Query: 472 EQLRVVGEDTKAQLLGGVDEAWALLQGLQ 500 + R+ + +Q L W LQG+Q Sbjct: 633 HEWRLEPSEGHSQEL-----PWVHLQGVQ 656
Score = 40.0 bits (92), Expect = 0.003 Identities = 65/278 (23%), Positives = 116/278 (41%), Gaps = 49/278 (17%) Query: 48 HLQKSELTQ----QLKKTGPSGIK----GREAEQLRRQLTPYAQRMERVLRENA-DSLQA 98 H + ELTQ + K+T + ++ R A++L + +E + ++A + + Sbjct: 258 HTAQLELTQANLQKEKETALTELREMLNSRRAQELALLQSRQQHELELLREQHAREKEEV 317 Query: 99 SLR--PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 LR A ELK K+ +E+ + ++++ + D +E LR+ L+ Q E L Sbjct: 318 VLRCGQEAAELKEKLQSEMEKNAQIVKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQ 377 Query: 157 HQLE----------GLTFQMKKNAE----ELKARISASAEELRQRL----APLAEDVR-- 196 +Q + FQ K AE L++ A+ E+LR+ L ED+ Sbjct: 378 NQFQKELAEQRAELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFK 437 Query: 197 ------------GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL----- 239 NL+ + E L+ E L Q++ R + E + L Sbjct: 438 FKESEKEKQLELENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHEQLLARTSR 497 Query: 240 VQQMEQLRQK-LGPHAGDVEGHLSFLEKDLRDKKFWYE 276 V+ +EQL+Q+ H ++E + EK LRD + Y+ Sbjct: 498 VEDLEQLKQREKTQHESELEQLRIYFEKKLRDAEKTYQ 535
Score = 35.4 bits (80), Expect = 0.066 Identities = 53/241 (21%), Positives = 99/241 (41%), Gaps = 37/241 (15%) Query: 26 QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRM 85 +V T D+ L +EA E Q+ + + + S + G + +R+ Sbjct: 2441 EVPTACPDWRGDLLQVVQEAFEKEQEMQGVELQPRLSGSDLGGHSS---------LLERL 2491 Query: 86 ERVLRENADSLQASLR----PHADELKAKID-----------QNVEELKGRLTPYADEFK 130 E+++RE D + SL P L ++I QN E+L+ L + Sbjct: 2492 EKIIREQGDLQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQNQEKLQ-HLRTALTSAE 2550 Query: 131 VKIDQTVEELRR--SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL 188 + Q +LRR L Y + ++ + L+ + ++ A ++ ++A +R Sbjct: 2551 ARGSQQEHQLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSVQKLLAAEQTVVRDLK 2610 Query: 189 APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ 248 + L E R +E L +SL E + Q+V + R + EN KA +Q++E + Sbjct: 2611 SDLCES-----RQKSEQLSRSLCE----VQQEVLQLRSMLSS-KENELKAALQELESEQG 2660 Query: 249 K 249 K Sbjct: 2661 K 2661
Score = 33.1 bits (74), Expect = 0.33 Identities = 43/199 (21%), Positives = 80/199 (40%), Gaps = 22/199 (11%) Query: 70 EAEQLRRQLTPYAQRMERVLRE-------------NADSLQASLRPHADELKAKIDQNVE 116 E E LRRQL AQ + E +A++ +A+LR ++L + + + Sbjct: 1364 ELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEAREAALRKEVEDLTKEQSETRK 1423 Query: 117 ELKGRLTPYADEFKVKIDQTVEEL--RRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE--- 171 + + + + K+ + E+L R A A+ L Q+ L ++ + Sbjct: 1424 QAEKDRSALLSQMKILESELEEQLSQHRGCAKQAEAVTA-LEQQVASLDKHLRNQRQFMD 1482 Query: 172 ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY 231 E A EE +Q + L +R + G + S LD +VE ++++ Sbjct: 1483 EQAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRDSQQ---APLDGEVELLQQKLREK 1539 Query: 232 GENFNKALVQQMEQLRQKL 250 + FN+ +Q+ RQ L Sbjct: 1540 LDEFNELAIQKESADRQVL 1558
Score = 32.7 bits (73), Expect = 0.43 Identities = 58/269 (21%), Positives = 109/269 (40%), Gaps = 40/269 (14%) Query: 53 ELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRME-----RVLRENADSLQA--SLRPHAD 105 +L +QL+K ++ + E L L Q + R L E SL+ + + Sbjct: 1657 DLKEQLEKM-KGDLESKNEEILHLNLKLDMQNSQTAVSLRELEEENTSLKVIYTRSSEIE 1715 Query: 106 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ 165 ELKA I+ N++E + RL E ++ + +E+L+ L+ E + Q L + Sbjct: 1716 ELKATIE-NLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHEVSDSQAGSLQSE 1774 Query: 166 MK----------------KNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS 209 + + A E K +S + +R + E ++ L+G E + Sbjct: 1775 LLCSQAGGPRGQALQGELEAALEAKEALSRLLADQERRHSQALEALQQRLQGAEEAAELQ 1834 Query: 210 LAELGGHL---DQQVEEFRRRVEPY--GENFNKALVQ----QMEQLRQKLGPHAGDVEGH 260 LAEL ++ + +VE+ R++ + +A + +++ L Q+ H+ ++E Sbjct: 1835 LAELERNVALREAEVEDMASRIQEFEAALKAKEATIAERNLEIDALNQRKAAHSAELEAV 1894 Query: 261 LSFLEKDLRDKKFWYELEDTCPVGGLPPP 289 L L + R LE G PP Sbjct: 1895 LLALARIRR------ALEQQPLAAGAAPP 1917
Score = 32.7 bits (73), Expect = 0.43 Identities = 128/611 (20%), Positives = 235/611 (38%), Gaps = 127/611 (20%) Query: 87 RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP 146 +V+R++ + L+ A KA++ + + +G L + FKV+ +L+ LA Sbjct: 1304 QVVRKHQELLECLKEESA--AKAELALELHKTQGTL----EGFKVE----TADLKEVLAG 1353 Query: 147 YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL 206 +D++ +L +LE L Q+++ A+E A+ E RL E + L Sbjct: 1354 -KEDSEHRLVLELESLRRQLQQAAQE-----QAALREECTRLWSRGEATATDAEAREAAL 1407 Query: 207 QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME----QLRQKLGPHAG------- 255 +K + + L ++ E R++ E AL+ QM+ +L ++L H G Sbjct: 1408 RKEVED----LTKEQSETRKQ----AEKDRSALLSQMKILESELEEQLSQHRGCAKQAEA 1459 Query: 256 --DVEGHLSFLEKDLRDKKFWYE-------------------LEDTCPVGGLPPPVFSEQ 294 +E ++ L+K LR+++ + + LE P P Sbjct: 1460 VTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAKPQPWGPRD 1519 Query: 295 VMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRD 354 S A L + LL Q + D F++ + K E +Q + +E + Sbjct: 1520 ---SQQAPLDGEVELLQ-----QKLREKLDEFNELAIQK---ESADRQVLMQEEEIKRLE 1568 Query: 355 DLGTKEMMEASSLTAWISVPFSRTLKDSLEQD-----LNNMNKFLEKLRPLSGSEAPRLP 409 ++ + + L V + + LEQD M+ L S +A R P Sbjct: 1569 EMNINIRKKVAQLQE--EVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQSTLDAGRCP 1626 Query: 410 QDPVG-----------------MRRQ-----LQEELEEVKARLQPYMAEAHELVGWNLEG 447 + P G +RR+ L+E+LE++K L+ ++ E++ NL+ Sbjct: 1627 EPPSGSPPEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKGDLE---SKNEEILHLNLK- 1682 Query: 448 LRQQLKPYTMDLM-EQVALRVQELQEQ---LRVVGEDTKAQLLGGVDEAWALLQGLQSRV 503 +D+ Q A+ ++EL+E+ L+V+ T++ + + LQ Q R+ Sbjct: 1683 ---------LDMQNSQTAVSLRELEEENTSLKVI--YTRSSEIEELKATIENLQENQKRL 1731 Query: 504 VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAK 563 E H E L +H L V S A + + S+ + + Sbjct: 1732 QKEKAEEIEQLHEVIEKL-----QHELSLMGPVVHEVSDSQAGSLQSELLCSQAGGPRGQ 1786 Query: 564 ALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFT 623 AL ++ L + +E LSR E ++QRLQ + LQ+A Sbjct: 1787 ALQGELEAAL-EAKEALSRLLADQERRH------SQALEALQQRLQGAEEAAELQLAELE 1839 Query: 624 RAIDQETEEVQ 634 R + EV+ Sbjct: 1840 RNVALREAEVE 1850
>gi|13431716|sp|Q9UKX2|MYH2_HUMAN Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa) Length = 1941 Score = 45.4 bits (106), Expect = 6e-05 Identities = 91/428 (21%), Positives = 171/428 (39%), Gaps = 52/428 (12%) Query: 89 LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYA 148 L + D L+ SL +L+ +++ +L+G L A E + I+ ++L L Sbjct: 1033 LEQQVDDLEGSLEQEK-KLRMDLERAKRKLEGDLK-LAQESIMDIENEKQQLDEKLKKKE 1090 Query: 149 ---QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLRGNT 203 + Q K+ + + L Q++K +EL+ARI EE+ A AE R +L Sbjct: 1091 FEISNLQSKIEDE-QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL 1149 Query: 204 EGLQKSLAELGGHLDQQVEEFRRRVEPYGE---NFNKALVQQMEQLRQKLGPHA------ 254 E + + L E GG Q+E ++R + + + +A +Q HA Sbjct: 1150 EEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAEL 1209 Query: 255 GDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFS 314 G+ +L +++ L +K ++E + ++ + M L L+ L + Sbjct: 1210 GEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE 1269 Query: 315 ATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKE-MMEASSLTAWISV 373 Q R + + +GR++ +G L KE ++ S Sbjct: 1270 EEQQR-----LINDLTAQRGRLQ---------TESGEFSRQLDEKEALVSQLSRGKQAFT 1315 Query: 374 PFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPY 433 LK LE+++ N L+ + + R+ EE +E KA LQ Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQS---------SRHDCDLLREQYEEEQESKAELQRA 1366 Query: 434 MAEAH-ELVGWNLEGLRQQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKA 483 +++A+ E+ W + ++ T +L E ++A R+Q +E + V E TK Sbjct: 1367 LSKANTEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQ 1425 Query: 484 QLLGGVDE 491 +L V++ Sbjct: 1426 RLQNEVED 1433
Score = 32.7 bits (73), Expect = 0.43 Identities = 93/512 (18%), Positives = 201/512 (39%), Gaps = 50/512 (9%) Query: 166 MKKNAEELK---ARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE 222 MK+ +++K A+ A +EL +++ L ++ + +L+ + + LA+ DQ ++ Sbjct: 858 MKEEFQKIKDELAKSEAKRKELEEKMVTLLKE-KNDLQLQVQAEAEGLADAEERCDQLIK 916 Query: 223 EFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCP 282 + E +A + E++ +L +E S L+KD+ D LE T Sbjct: 917 TKIQLEAKIKEVTERA--EDEEEINAELTAKKRKLEDECSELKKDIDD------LELT-- 966 Query: 283 VGGLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGD----KGRV 336 L + + LT +A L A T+ +K + QT D + +V Sbjct: 967 ---LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023 Query: 337 EQIHQQKMAREPA-----GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMN 391 + + K+ E GS+ + + +E + + ++ +E + ++ Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083 Query: 392 KFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQ 451 + L+K + S +D + QLQ++++E++AR++ E + +Q+ Sbjct: 1084 EKLKK-KEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQR 1142 Query: 452 LKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD---EAWALLQGLQSRVVHHTG 508 ++ ++E+ E+L G T AQ+ E + + L+ + H Sbjct: 1143 ---------SDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1193 Query: 509 RFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKA---- 564 L +A+S V+ +G + L R V + + + L+ + +KA Sbjct: 1194 TAATLRKKHADS-VAELGEQIDNLQR-VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251 Query: 565 --LHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAF 622 + ++ L +L+ + Q S E ++L ++ Q++ Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE-KEALVSQLSRG 1310 Query: 623 TRAIDQETEEVQQQLAPPPPGHSAFAPEFQQT 654 +A Q+ EE+++QL +A A Q + Sbjct: 1311 KQAFTQQIEELKRQLEEEIKAKNALAHALQSS 1342
>gi|1730009|sp|P12270|TPR_HUMAN Nucleoprotein TPR Length = 2349 Score = 45.4 bits (106), Expect = 6e-05 Identities = 48/208 (23%), Positives = 95/208 (45%), Gaps = 19/208 (9%) Query: 67 KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID-QNVEELKGRLTPY 125 K + Q+++ Y + E + + ++ S + D + + Q ++ELK L Sbjct: 1427 KVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486 Query: 126 ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR 185 + K ++ VE L+++L+ + + L Q L ++ + ++L+ R + E+LR Sbjct: 1487 ETKSK-SLESQVENLQKTLSEKETEARN-LQEQTVQLQSELSRLRQDLQDR-TTQEEQLR 1543 Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ---QVEEFRRRVEPYGENFNKALVQQ 242 Q++ E R + + +A L G DQ + EE ++R N AL QQ Sbjct: 1544 QQITEKEEKTRKAI----VAAKSKIAHLAGVKDQLTKENEELKQR--------NGALDQQ 1591 Query: 243 MEQLRQKLGPHAGDVEGHLSFLEKDLRD 270 ++L ++ EG +S LE++LR+ Sbjct: 1592 KDELDVRITALKSQYEGRISRLERELRE 1619
Score = 42.7 bits (99), Expect = 4e-04 Identities = 60/254 (23%), Positives = 109/254 (42%), Gaps = 24/254 (9%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLREN 92 D + L N KE +++ QK T K S ++ + A Q Q T Q + E+ Sbjct: 881 DTETNLHLNTKELLKNAQKEIATL---KQHLSNMEVQVASQ-SSQRTGKGQPSNK---ED 933 Query: 93 ADSLQASLRP---HADELKAKID---QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP 146 D L + LR ++LK ++ NVE+ + +T + K Q EE+R+++ Sbjct: 934 VDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLN-KEKQVTEEVRKNIEV 992 Query: 147 YAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL 206 +++ E QLE +++K +EL+ + E + Q+L+ L + + E L Sbjct: 993 RLKESAE-FQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEAL 1051 Query: 207 QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK 266 Q++ L ++ RR + K V+ + ++L HA DVE + E+ Sbjct: 1052 QRASTALSNE-----QQARRDCQEQA----KIAVEAQNKYERELMLHAADVEALQAAKEQ 1102 Query: 267 DLRDKKFWYELEDT 280 + LE+T Sbjct: 1103 VSKMASVRQHLEET 1116
Score = 40.8 bits (94), Expect = 0.002 Identities = 113/513 (22%), Positives = 201/513 (39%), Gaps = 91/513 (17%) Query: 36 SQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGR------EAEQ----LRRQLTPYAQRM 85 ++L+ K L+K QQ + G+KGR E+EQ + ++L+ +R+ Sbjct: 12 TELNKLPKSVQNKLEKFLADQQSEI---DGLKGRHEKFKVESEQQYFEIEKRLSHSQERL 68 Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 RE SL+ L ++LKA ++N E A + + I + L Sbjct: 69 VNETRE-CQSLRLELEKLNNQLKALTEKNKE------LEIAQDRNIAIQSQFTRTKEELE 121 Query: 146 PYAQD---TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL-AEDVRGNLRG 201 +D T E+L+ +LE LT +K+ E+LK + + EL+ +L L A DV R Sbjct: 122 AEKRDLIRTNERLSQELEYLTEDVKRLNEKLK-ESNTTKGELQLKLDELQASDVSVKYRE 180 Query: 202 -----------------NTEGLQKS--LAELGGHLDQQVEEFRRRVEPYGENFNKALVQQ 242 NTE K+ L LG ++ E + +E E ++ L +Q Sbjct: 181 KRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSR-LEEQ 239 Query: 243 MEQLR---QKLGPHAGDVEGHLSFLEKD--LRDKKFWYELEDTCPVGGLPPPVFSEQVMA 297 M L+ + L H D+ L ++ ++KF EL + L + Sbjct: 240 MNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAK 299 Query: 298 SMAAVLTWALALLSAF--SATQARKGFWDYFSQTSGDKGRVEQIHQQKMAR--------- 346 S LT A+ L A +A K D+ + K ++E+ +K+ R Sbjct: 300 SNE--LTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENAN 357 Query: 347 ------EPAGSVRDDLGTKEMMEASSLTAWISVP----------FSRTLKDSLEQDLNN- 389 + G++ + M ++ A I P + T L + L N Sbjct: 358 DLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENK 417 Query: 390 -MNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHEL-------- 440 +NK+L+++ ++AP L + R Q+ + + +L+ M E L Sbjct: 418 RINKYLDEIVKEVEAKAPILKRQREEYER-AQKAVASLSVKLEQAMKEIQRLQEDTDKAN 476 Query: 441 -VGWNLEGLRQQLKPYTMDLMEQVALRVQELQE 472 LE ++++ DL +Q+ + + EL+E Sbjct: 477 KQSSVLERDNRRMEIQVKDLSQQIRVLLMELEE 509
Score = 35.8 bits (81), Expect = 0.051 Identities = 101/517 (19%), Positives = 202/517 (39%), Gaps = 61/517 (11%) Query: 85 MERVL-RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS 143 +++VL R + L S++ ++ A ++ LKGR ++FKV+ +Q E+ + Sbjct: 5 LQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGR----HEKFKVESEQQYFEIEKR 60 Query: 144 LAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE-ELRQRLAPLAEDVRGNLRGN 202 L+ ++Q+ + + L +++K +LKA + E E+ Q + + Sbjct: 61 LS-HSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEE 119 Query: 203 TEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGP-HAGDVEGHL 261 E ++ L L Q++E V+ E ++ + E L+ KL A DV + Sbjct: 120 LEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGE-LQLKLDELQASDVS--V 176 Query: 262 SFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKG 321 + EK L +K ++T + + T L L + + Sbjct: 177 KYREKRLEQEKELLHSQNTW--------------LNTELKTKTDELLALGREKGNEILEL 222 Query: 322 FWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKD 381 + ++ EQ++ K + E +DL TK + EA A Sbjct: 223 KCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK-LKEAKEQQA------------ 269 Query: 382 SLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELV 441 S+E+ +N KL L S A D +L +EE+ +L EA++ + Sbjct: 270 SMEEKFHNELNAHIKLSNLYKSAA----DDSEAKSNELTRAVEELH-KLLKEAGEANKAI 324 Query: 442 GWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWAL--LQGL 499 +L + Q +++E++ +EL+ ++ + + +E A+ Sbjct: 325 QDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAA 384 Query: 500 QSRVVHHTGRFKELFHPYAESL---------VSGIGRHVQELHRSVAPHAP------ASP 544 +++V + EL++ Y E+ I +++ E+ + V AP Sbjct: 385 VAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEY 444 Query: 545 ARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELS 581 R + V LS KL K + R+Q++ D+ ++ S Sbjct: 445 ERAQKAVASLSVKLEQAMKEIQ-RLQEDTDKANKQSS 480
Score = 30.8 bits (68), Expect = 1.6 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 17/126 (13%) Query: 39 SNNAKEAVEHLQK--SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 + N +E LQ S L Q L+ + + EQLR+Q+T ++ + + + Sbjct: 1511 ARNLQEQTVQLQSELSRLRQDLQD------RTTQEEQLRQQITEKEEKTRKAIVAAKSKI 1564 Query: 97 ------QASLRPHADELKAK---IDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY 147 + L +ELK + +DQ +EL R+T +++ +I + ELR + Sbjct: 1565 AHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERH 1624 Query: 148 AQDTQE 153 + E Sbjct: 1625 LEQRDE 1630
>gi|13431724|sp|Q9Y623|MYH4_HUMAN Myosin heavy chain, skeletal muscle, fetal (Myosin heavy chain IIb) (MyHC-IIb) Length = 1939 Score = 45.4 bits (106), Expect = 6e-05 Identities = 96/435 (22%), Positives = 174/435 (40%), Gaps = 82/435 (18%) Query: 108 KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA---PYAQDT-------QEKLNH 157 K K++Q V++L+G L E + K+ +E +R L AQ++ +++LN Sbjct: 1028 KTKLEQQVDDLEGSL-----EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNE 1082 Query: 158 QL-----------------EGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGN 198 +L + L Q++K +EL+ARI EE+ A AE R + Sbjct: 1083 KLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142 Query: 199 LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ-------LRQKLG 251 L E + + L E GG Q+E ++R E + + L + Q LR+K Sbjct: 1143 LSRELEEISERLEEAGGATSAQIELNKKR-EAEFQKMRRDLEESTLQHEATAAALRKKHA 1201 Query: 252 PHAGDVEGHLSFLEK---DLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALA 308 ++ + L++ L +K ++E + ++ M L L+ Sbjct: 1202 DSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLS 1261 Query: 309 LLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLT 368 + Q R ++ S K R +H + +G L K+ M S L+ Sbjct: 1262 EIKTKEEEQQR-----LINELSAQKAR---LHTE------SGEFSRQLDEKDAM-VSQLS 1306 Query: 369 AWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRL--PQDPVGMRRQLQEELEEV 426 K + Q + + + LE+ + A L + + R+ EE +E Sbjct: 1307 RG---------KQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEA 1357 Query: 427 KARLQPYMAEAH-ELVGWNLEGLRQQLKPYTMDLME---QVALRVQELQEQLRVVG---- 478 KA LQ M++A+ E+ W + ++ T +L E ++A R+Q+ +E + V Sbjct: 1358 KAELQRGMSKANSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416 Query: 479 --EDTKAQLLGGVDE 491 E TK +L V++ Sbjct: 1417 SLEKTKQRLQNEVED 1431
Score = 38.9 bits (89), Expect = 0.006 Identities = 106/514 (20%), Positives = 204/514 (39%), Gaps = 46/514 (8%) Query: 158 QLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL 217 ++ + + +K EEL A+ A +EL +++ L ++ + +L+ + +LA+ Sbjct: 852 EMANMKEEFEKTKEEL-AKTEAKRKELEEKMVTLMQE-KNDLQLQVQAEADALADAEERC 909 Query: 218 DQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYEL 277 DQ ++ + E +A + E++ +L +E S L+KD+ D L Sbjct: 910 DQLIKTKIQLEAKIKEVTERA--EDEEEINAELTAKKRKLEDECSELKKDIDD------L 961 Query: 278 EDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGDKGR 335 E T L + + LT +A L A T+ +K + QT D Sbjct: 962 ELT-----LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQM 1016 Query: 336 VE-QIHQQKMAREPAGSVRDDL-GTKEM-------MEASSLTAWISVPFSRTLKDSLEQD 386 E +++ A+ DDL G+ E +E + + ++ E D Sbjct: 1017 EEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTEND 1076 Query: 387 LNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLE 446 +N+ L+K + S +D + QLQ++++E++AR++ E + Sbjct: 1077 KQQLNEKLKK-KEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAK 1135 Query: 447 GLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQL-LGGVDEA--WALLQGLQSRV 503 +Q+ ++ ++E+ E+L G T AQ+ L EA + + L+ Sbjct: 1136 AEKQR---------SDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEEST 1186 Query: 504 VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKL--TLK 561 + H L +A+S V+ +G+ + L R V + L + L+ + K Sbjct: 1187 LQHEATAAALRKKHADS-VAELGKQIDSLQR-VKQKLEKEKSELKMEINDLASNMETVSK 1244 Query: 562 AKALHARIQQNL-DQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQ-RLQAFRQDTYL-Q 618 AKA ++ + L DQL E ++ L E + Q +D + Q Sbjct: 1245 AKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQ 1304 Query: 619 IAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQ 652 ++ +A Q+ EE+++QL S A Q Sbjct: 1305 LSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQ 1338
Score = 28.5 bits (62), Expect = 8.1 Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 12/152 (7%) Query: 42 AKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLR 101 A+E + S +++KK +K L+ +L Q + ++ L+A +R Sbjct: 1770 AEELKKEQDTSAHLERMKKNMEQTVK-----DLQLRLGEAEQLALKGGKKQIQKLEARVR 1824 Query: 102 PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG 161 E++++ NVE +KG L + K QT E+ + L QD +KL +++ Sbjct: 1825 ELESEVESEQKHNVEAVKG-LRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQTKVKA 1881 Query: 162 LTFQMKKNAEELKARISASAEELRQRLAPLAE 193 K+ AEE + + + + + R+ L E Sbjct: 1882 ----YKRQAEEAEEQSNVNLAKFRKLQHELEE 1909
>gi|3041706|sp|P13533|MYH6_HUMAN Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha) Length = 1939 Score = 45.1 bits (105), Expect = 8e-05 Identities = 100/470 (21%), Positives = 191/470 (40%), Gaps = 78/470 (16%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRP--HADELKAKIDQNVEELKGRLTPYADEF 129 +++ +LT + ++ ++ D LQ + K K++Q V++L+G L E Sbjct: 988 DEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLE---QEK 1044 Query: 130 KVKIDQTVEELRRSLAPYAQDTQEKL------------------------NHQLE---GL 162 KV++D +E +R L + TQE + N ++E L Sbjct: 1045 KVRMD--LERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQAL 1102 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPLA--EDVRGNLRGNTEGLQKSLAELGGHLDQQ 220 Q++K +E +ARI EEL A E +R +L E + + L E GG Q Sbjct: 1103 ALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ 1162 Query: 221 VEEFRRRVEPYGE---NFNKALVQQMEQLRQKLGPHA------GDVEGHLSFLEKDLRDK 271 +E ++R + + + +A +Q HA G+ +L +++ L + Sbjct: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222 Query: 272 KFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSG 331 K ++LE + V ++M ++ A A L S T + Sbjct: 1223 KSEFKLE-------------LDDVTSNMEQIIK-AKANLEKVSRTLEDQANEYRVKLEEA 1268 Query: 332 DKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMN 391 + + Q+ + G + L KE + S LT + +++ ++D L++ L Sbjct: 1269 QRSLNDFTTQRAKLQTENGELARQLEEKEAL-ISQLTRG-KLSYTQQMED-LKRQLEEEG 1325 Query: 392 KFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAH-ELVGWNLEGLRQ 450 K L + A + + + R+ EE E KA LQ +++A+ E+ W + Sbjct: 1326 KAKNAL-----AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1380 Query: 451 QLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLLGGVDE 491 ++ T +L E ++A R+Q+ +E + V E TK +L +++ Sbjct: 1381 AIQ-RTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIED 1429
Score = 34.7 bits (78), Expect = 0.11 Identities = 98/509 (19%), Positives = 203/509 (39%), Gaps = 53/509 (10%) Query: 165 QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF 224 ++K+ E+ +AR +EL +++ L ++ + +L+ + Q +L + DQ ++ Sbjct: 860 RIKETLEKSEAR----RKELEEKMVSLLQE-KNDLQLQVQAEQDNLNDAEERCDQLIKN- 913 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVG 284 + ++E + N+ L + E++ +L +E S L+KD+ D LE T Sbjct: 914 KIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKKDIDD------LELT---- 962 Query: 285 GLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGD----KGRVEQ 338 L + + LT +A L A T+ +K + Q D + +V Sbjct: 963 -LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNS 1021 Query: 339 IHQQKMAREPA-----GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKF 393 + + K+ E GS+ + + +E + + ++ LE D + + Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081 Query: 394 LEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPY--MAEAHELVGWNLEGLRQQ 451 L+K + ++ +D + QLQ++L+E +AR++ EA +E LR Sbjct: 1082 LKKKEFDINQQNSKI-EDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSD 1140 Query: 452 LKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD---EAWALLQGLQSRVVHHTG 508 L + ++E+ E+L G T Q+ E + + L+ + H Sbjct: 1141 L-----------SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1189 Query: 509 RFKELFHPYAESLVSGIGRHVQELHR-SVAPHAPASPARLSRCVQVLSRKLTLKAKALHA 567 L +A+S V+ +G + L R S +L + + +KAKA Sbjct: 1190 TAAALRKKHADS-VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1248 Query: 568 RIQQNLD----QLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFT 623 ++ + L+ + R +L A Q + E+ ++L+ ++ Q+ Sbjct: 1249 KVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE-KEALISQLTRGK 1307 Query: 624 RAIDQETEEVQQQLAPPPPGHSAFAPEFQ 652 + Q+ E++++QL +A A Q Sbjct: 1308 LSYTQQMEDLKRQLEEEGKAKNALAHALQ 1336
Score = 33.5 bits (75), Expect = 0.25 Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 32/207 (15%) Query: 47 EHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE 106 E ++ SE Q L S I + +++ LT +E ++E ++ + + + D Sbjct: 1707 ELIETSERVQLLHSQNTSLIN--QKKKMEADLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764 Query: 107 LKAKIDQNVEELKGR--LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTF 164 EELK + + + K ++QT+++L+ L D E++ L+G Sbjct: 1765 AMM-----AEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-----DEAEQI--ALKG--- 1809 Query: 165 QMKKNAEELKARISASAEELRQRLAPLAEDVRG---------NLRGNTEGLQKSLAELGG 215 KK ++L+AR+ EL AE V+G L TE +K+L L Sbjct: 1810 -GKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQD 1868 Query: 216 HLDQ---QVEEFRRRVEPYGENFNKAL 239 +D+ +V+ ++R+ E E N L Sbjct: 1869 LVDKLQLKVKAYKRQAEEAEEQANTNL 1895
Score = 30.8 bits (68), Expect = 1.6 Identities = 126/631 (19%), Positives = 237/631 (37%), Gaps = 129/631 (20%) Query: 36 SQLSNNAKEAVEHLQKS------ELTQQLKKTGPSGIKGREAEQ--LRRQLTPYAQRMER 87 S LS +E E L+++ ++ K+ R+ E+ L+ + T A R + Sbjct: 1139 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKH 1198 Query: 88 V-----LRENADSLQA---SLRPHADELKAKIDQ-------------NVEELKGRLTPYA 126 L E D+LQ L E K ++D N+E++ L A Sbjct: 1199 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQA 1258 Query: 127 DEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ 186 +E++VK+ EE +RSL + T ++ Q E N E A +L + Sbjct: 1259 NEYRVKL----EEAQRSLNDF---TTQRAKLQTE--------NGE--------LARQLEE 1295 Query: 187 RLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQL 246 + A +++ RG L QQ+E+ +R++E G+ N AL ++ Sbjct: 1296 KEALISQLTRGKL----------------SYTQQMEDLKRQLEEEGKAKN-ALAHALQSA 1338 Query: 247 RQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWA 306 R H D+ LR++ YE E + A + VL+ A Sbjct: 1339 R-----HDCDL----------LREQ---YEEE--------------TEAKAELQRVLSKA 1366 Query: 307 LALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDL-GTKEMMEAS 365 + ++ + K +++ + A E + L TK ++ Sbjct: 1367 NSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNE 1426 Query: 366 SLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEE 425 + V S +L++ N +K L + + L + R L EL + Sbjct: 1427 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL-ESSQKEARSLSTELFK 1485 Query: 426 VKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQL 485 +K + + N + L++++ T L E V EL E++R E K +L Sbjct: 1486 LKNAYEESLEHLETFKREN-KNLQEEISDLTEQLGEG-GKNVHEL-EKVRKQLEVEKLEL 1542 Query: 486 LGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH-APASP 544 ++EA A L+ + +++ R + F+ + + +E+ ++ H Sbjct: 1543 QSALEEAEASLEHEEGKIL----RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDS 1598 Query: 545 ARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEV 604 + S + SR L+ K +++ +L+++ +LS A +M +E Sbjct: 1599 LQTSLDAETRSRNEVLRVK---KKMEGDLNEMEIQLSHA-------------NRMAAEAQ 1642 Query: 605 RQ--RLQAFRQDTYLQIAAFTRAIDQETEEV 633 +Q LQ+ +DT +Q+ RA D E + Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENI 1673
>gi|3041707|sp|P13535|MYH8_HUMAN Myosin heavy chain, skeletal muscle, perinatal (MyHC-perinatal) Length = 1937 Score = 44.7 bits (104), Expect = 1e-04 Identities = 101/485 (20%), Positives = 197/485 (40%), Gaps = 81/485 (16%) Query: 44 EAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPH 103 E + L K + + L++T + +AE+ + + A+ L + D L+ SL Sbjct: 990 ETIAKLSKEK--KALQETHQQTLDDLQAEEDKVNILTKAKTK---LEQQVDDLEGSLEQE 1044 Query: 104 ADELKAKIDQNVEELKGRL------TPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNH 157 +L+ +++ +L+G L T + K ++D+ +E+ ++ +++ Sbjct: 1045 K-KLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDE--- 1100 Query: 158 QLEGLTFQMKKNAEELKARISASAEELRQRLA--PLAEDVRGNLRGNTEGLQKSLAELGG 215 + + Q++K +EL+ARI EE+ A AE R +L E + + L E GG Sbjct: 1101 --QAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1158 Query: 216 HLDQQVEEFRRRVEPYGE---NFNKALVQ---QMEQLRQK-------LGPHAGDVEGHLS 262 QVE ++R + + + +A +Q + LR+K LG +++ Sbjct: 1159 ATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQ 1218 Query: 263 FLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGF 322 LEK+ + K E +D ++S A ++ A L + Sbjct: 1219 KLEKEKSELKM--ETDD----------------LSSNAEAISKAKGNLEKMC-----RSL 1255 Query: 323 WDYFSQTSGDKGRVEQI-----HQQKMAREPAGSVRDDLGTKE-MMEASSLTAWISVPFS 376 D S+ + +++ Q+ + AG L K+ ++ S + S Sbjct: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI 1315 Query: 377 RTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAE 436 LK LE++ N L+ + + R+ EE +E KA LQ +++ Sbjct: 1316 EELKHQLEEETKAKNALAHALQS---------SRHDCDLLREQYEEEQEGKAELQRALSK 1366 Query: 437 AH-ELVGWNLEGLRQQLKPYTMDLME---QVALRVQELQEQLRVVG------EDTKAQLL 486 A+ E+ W + ++ T +L E ++A R+QE +E + V E TK +L Sbjct: 1367 ANSEVAQWRTKYETDAIQ-RTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 1425 Query: 487 GGVDE 491 V++ Sbjct: 1426 NEVED 1430
Score = 33.9 bits (76), Expect = 0.19 Identities = 100/512 (19%), Positives = 200/512 (39%), Gaps = 52/512 (10%) Query: 165 QMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEF 224 + +K +EL A+ A +EL +++ L ++ + +L+ + SLA+ +Q ++ Sbjct: 858 EFQKTKDEL-AKSEAKRKELEEKMVTLLKE-KNDLQLQVQSEADSLADAEERCEQLIKNK 915 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVG 284 + E +A ++ E++ +L +E S L+KD+ D LE T Sbjct: 916 IQLEAKIKEVTERA--EEEEEINAELTAKKRKLEDECSELKKDIDD------LELT---- 963 Query: 285 GLPPPVFSEQVMASMAAVLTWALALLSAFSA--TQARKGFWDYFSQTSGD----KGRVEQ 338 L + + LT +A L A ++ +K + QT D + +V Sbjct: 964 -LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022 Query: 339 IHQQKMAREPA-----GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKF 393 + + K E GS+ + + +E + + ++ +E D +++ Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082 Query: 394 LEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLK 453 LEK + S +D + QLQ++++E++AR+ E +G +E R + Sbjct: 1083 LEK-KEFEISNLISKIEDEQAVEIQLQKKIKELQARI--------EELGEEIEAERAS-R 1132 Query: 454 PYTMDLMEQVALRVQELQEQLRVVGEDTKAQL-LGGVDEA--WALLQGLQSRVVHHTGRF 510 ++ ++E+ E+L G T AQ+ L EA L + L+ + H Sbjct: 1133 AKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMV 1192 Query: 511 KELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQ 570 L +A+S+ +G + L R V + L LS +KA ++ Sbjct: 1193 AALRKKHADSMAE-LGEQIDNLQR-VKQKLEKEKSELKMETDDLSSNAEAISKA-KGNLE 1249 Query: 571 QNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYL--------QIAAF 622 + L +++S D + ++ R + +A L Q++ Sbjct: 1250 KMCRSLEDQVSELKTKEEEQQRLIND--LTAQRARLQTEAGEYSRQLDEKDALVSQLSRS 1307 Query: 623 TRAIDQETEEVQQQLAPPPPGHSAFAPEFQQT 654 +A Q+ EE++ QL +A A Q + Sbjct: 1308 KQASTQQIEELKHQLEEETKAKNALAHALQSS 1339
Score = 29.3 bits (64), Expect = 4.8 Identities = 48/228 (21%), Positives = 101/228 (44%), Gaps = 34/228 (14%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKG--REAEQLRRQLTPYAQRMERVLRENAD 94 QL++ + A E L+ TQ + K + R E L+ QL ++ A+ Sbjct: 1631 QLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA--------IVERRAN 1682 Query: 95 SLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK 154 LQA + +EL A ++Q K A++ + + V+ L +T++K Sbjct: 1683 LLQAEI----EELWATLEQTERSRK-----IAEQELLDASERVQLLHTQNTSLI-NTKKK 1732 Query: 155 LNHQLEGLTFQMKKNAEELKARISASAEELRQRL----APLAEDVRGNLRGNTEGLQKSL 210 L + + L ++++ +E S +AEE ++ A +AE+++ + L Sbjct: 1733 LENDVSQLQSEVEEVIQE-----SRNAEEKAKKAITDAAMMAEELK-----KEQDTSAHL 1782 Query: 211 AELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVE 258 + +L+Q V++ + R++ + K +Q+++L ++ G+VE Sbjct: 1783 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVE 1830
>gi|33301318|sp|Q92614|MY18A_HUMAN Myosin XVIIIA (Myosin 18A) (Myosin containing PDZ domain) Length = 2054 Score = 43.5 bits (101), Expect = 2e-04 Identities = 114/618 (18%), Positives = 232/618 (37%), Gaps = 109/618 (17%) Query: 39 SNNAKEAVEHLQKS--ELTQQLKKTG----PSGIKGREAEQLRR-------QLTPYAQRM 85 S ++ A++ L+K LT +L+ T ++ E E+ +R Q AQR Sbjct: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR- 1476 Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 E++ RE + L A LK ++++ ++ G F K+ EL+ + Sbjct: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAG--------FTQKVVSLEAELQDISS 1528 Query: 146 PYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLA--EDVRGNLRGNT 203 ++D E ++KK +L+A++ EEL ++ + E + L Sbjct: 1529 QESKD---------EASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579 Query: 204 EGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF 263 E ++++ ++ D++VEE R+ + + L ++ E +QK+ ++EG L+ Sbjct: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED-KQKVLREKRELEGKLAT 1638 Query: 264 LEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFW 323 L + + F E + + A+L A +L Sbjct: 1639 LSDQVNRRDFESEKR-------------LRKDLKRTKALLADAQLML------------- 1672 Query: 324 DYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSL 383 D+ ++ K + Q+ K +E S T +V + ++ + Sbjct: 1673 DHLKNSAPSKREIAQL-------------------KNQLEESEFTCAAAVKARKAMEVEI 1713 Query: 384 EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVG- 442 E DL+ + K + + RL ++ ++ +L+E+ E++ ++ + A + Sbjct: 1714 E-DLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772 Query: 443 -WNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQS 501 + L+ QL E+ QELQE+L+ + + VD++ Q + Sbjct: 1773 LAQINDLQAQL--------EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKI 1824 Query: 502 RVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLK 561 R + F+ ESL S + ++++L A + Sbjct: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN----------------R 1868 Query: 562 AKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQM---LSEEVRQRLQAFRQDTYLQ 618 K + R+Q+ L +EE+ + +M E Q LQA + + + Sbjct: 1869 EKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKR 1928 Query: 619 IAAFTRAIDQETEEVQQQ 636 I AI+ E E + + Sbjct: 1929 IGDLQAAIEDEMESDENE 1946
Score = 34.3 bits (77), Expect = 0.15 Identities = 52/270 (19%), Positives = 113/270 (41%), Gaps = 38/270 (14%) Query: 38 LSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQ 97 L K+ E L + T Q+ + ++ E E++R+ + + + + E S Q Sbjct: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLE-MEMERMRQTHSKEMESRDEEVEEARQSCQ 1605 Query: 98 ASLRPHADEL------KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL---APYA 148 L+ +L K K+ + EL+G+L +D+ + ++ + LR+ L Sbjct: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665 Query: 149 QDTQEKLNH---------QLEGLTFQMKKN----AEELKAR--ISASAEELRQRLAPLAE 193 D Q L+H ++ L Q++++ A +KAR + E+L ++ +A+ Sbjct: 1666 ADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK 1725 Query: 194 DVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGE------------NFNKALVQ 241 + L LQ+ E+ L++ E+ ++ + N +A ++ Sbjct: 1726 -AKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLE 1784 Query: 242 QMEQLRQKLGPHAGDVEGHLSFLEKDLRDK 271 + + +Q+L ++ + FLE+ + DK Sbjct: 1785 EANKEKQELQEKLQALQSQVEFLEQSMVDK 1814
>gi|464541|sp|P35241|RADI_HUMAN Radixin Length = 583 Score = 43.1 bits (100), Expect = 3e-04 Identities = 61/237 (25%), Positives = 99/237 (41%), Gaps = 34/237 (14%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGR-----------EAEQLRRQLTPYAQRM 85 +++ KE +E +K EL ++LK+ IK + E +Q R++ A+R+ Sbjct: 331 EIAEKEKERIER-EKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERL 389 Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 E+ R ++ A + AD++K N E+L L EF KI +EE ++ Sbjct: 390 EKERRAAEEAKSAIAKQAADQMK-----NQEQLAAELA----EFTAKI-ALLEEAKKKKE 439 Query: 146 PYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEG 205 A + Q K E L +K EELK +SA + P E+ + E Sbjct: 440 EEATEWQHKAFAAQEDL----EKTKEELKTVMSAPPPPPPPPVIPPTENEHDE---HDEN 492 Query: 206 LQKSLAELG--GHLDQQVEEFRRRVEPYGENFNK---ALVQQMEQLRQKLGPHAGDV 257 ++ AEL G ++ + EE R E K AL ++ Q R + DV Sbjct: 493 NAEASAELSNEGVMNHRSEEERVTETQKNERVKKQLQALSSELAQARDETKKTQNDV 549
>gi|2506805|sp|P24043|LMA2_HUMAN Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain) Length = 3110 Score = 41.6 bits (96), Expect = 0.001 Identities = 99/503 (19%), Positives = 204/503 (40%), Gaps = 77/503 (15%) Query: 54 LTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQ 113 LT+ K T G++AE+ + A+ + ++E A +A +E K+++ Sbjct: 1651 LTRATKVTADGEQTGQDAERTNTR----AKSLGEFIKELARDAEA-----VNEKAIKLNE 1701 Query: 114 NVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEEL 173 + + + +IDQ ++ELRR ++ E E L ++KK E Sbjct: 1702 TLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEIAEDELVAAEALLKKVKKLFGES 1761 Query: 174 KARISASAEELRQRLAPL---AEDVRGNLRGNTEGL----------QKSLAELGGHLDQQ 220 + ++LR++LA +D LR T+ + QK++ L + Sbjct: 1762 RGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTAL-EKKKEA 1820 Query: 221 VEEFRRRVEPYGENFN-------------KALVQQMEQLRQKLGPHAGDVEGHLSFLEKD 267 VE +R++E + N +++ +E ++ KL P + ++ + L ++ Sbjct: 1821 VESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQE 1880 Query: 268 LRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWAL--ALLSAFSATQARKGF--- 322 ++D+K ++ + Q+ S +AVL L A +F+AT A K + Sbjct: 1881 IKDRKLAEKVSQA--------ESHAAQLNDS-SAVLDGILDEAKNISFNATAAFKAYSNI 1931 Query: 323 WDYFSQTSGDKGRVEQIHQQ--KMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLK 380 DY + + + + K+A P G +++D K ++ S + + +K Sbjct: 1932 KDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKED--AKGCLQKSFRILNEAKKLANDVK 1989 Query: 381 DSLEQDLNNMNKFLEK--------LRPLSGS--EAPRLPQDPVGMRRQLQEELEEVKARL 430 ++ E LN + +E LR L+ + + +P D + ++++ + Sbjct: 1990 EN-EDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTA 2048 Query: 431 QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD 490 + +A+ EL NL+GL++ L + VA + VV + +K +++ D Sbjct: 2049 KDVLAQITEL-HQNLDGLKKNYN----KLADSVA-------KTNAVVKDPSKNKIIADAD 2096 Query: 491 EAWALLQGLQSRVVHHTGRFKEL 513 L+ R++ KEL Sbjct: 2097 ATVKNLEQEADRLIDKLKPIKEL 2119
>gi|48474907|sp|Q8WYA0|CDV1_HUMAN Carnitine deficiency-associated protein expressed in ventricle 1 (CDV-1 protein) Length = 676 Score = 41.6 bits (96), Expect = 0.001 Identities = 49/244 (20%), Positives = 99/244 (40%), Gaps = 44/244 (18%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRP 102 K+ E++Q+ T + KK GI G Q + +ERV ++L+ Sbjct: 436 KQRHENIQQQLQTMEEKK----GISGYSYTQ---------EELERV---------SALKS 473 Query: 103 HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE--KLNHQLE 160 DE+K + ++ E+ +L E K + ++ELR+ Y + TQE + Q + Sbjct: 474 EVDEMKGRTLDDMSEMVKKLYSLVSEKKSALASVIKELRQLRQKYQELTQECDEKKSQYD 533 Query: 161 GLTFQMKKNAEELKARISASAEELRQRLAP------LAEDVRGNLRGNTEGLQKSLAELG 214 ++ N +L+ + EE Q + + +++ LR T+ ++ ++ Sbjct: 534 SCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMKAYISSDQ 593 Query: 215 GHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFW 274 + + E + EN K L ++ + +R+ GP +++ K W Sbjct: 594 QEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGP--------------NMKQAKMW 639 Query: 275 YELE 278 +LE Sbjct: 640 RDLE 643
>gi|118685|sp|P11532|DMD_HUMAN Dystrophin Length = 3685 Score = 41.6 bits (96), Expect = 0.001 Identities = 41/181 (22%), Positives = 78/181 (43%), Gaps = 23/181 (12%) Query: 71 AEQLRRQLTPYAQRMERVLRENADSLQASLRPH---ADELKAKIDQNVEELKGRLTPYAD 127 AE+ L Y + ME +N D + + DE + K Q E++ RL + Sbjct: 1667 AEEWLNLLLEYQKHME-TFDQNVDHITKWIIQADTLLDESEKKKPQQKEDVLKRLKAELN 1725 Query: 128 EFKVKIDQTVEELRRSLAPYAQDTQE-------KLNHQLEGLTFQMK--------KNAEE 172 + + K+D T ++ +A ++ +LNH+ ++ ++K K E+ Sbjct: 1726 DIRPKVDSTRDQAANLMANRGDHCRKLVEPQISELNHRFAAISHRIKTGKASIPLKELEQ 1785 Query: 173 LKARISASAE----ELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRV 228 + I E E++Q + ED ++ + EG K L + G +L Q++ + R+R Sbjct: 1786 FNSDIQKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKRE 1845 Query: 229 E 229 E Sbjct: 1846 E 1846
Score = 33.5 bits (75), Expect = 0.25 Identities = 70/353 (19%), Positives = 141/353 (39%), Gaps = 59/353 (16%) Query: 25 DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLK------KTGPSGIKGREAEQLRRQL 78 DQ A +M + ++ ++ VE Q SEL + KTG + I +E EQ + Sbjct: 1736 DQAANLM----ANRGDHCRKLVEP-QISELNHRFAAISHRIKTGKASIPLKELEQFNSDI 1790 Query: 79 TPYAQRMERVLRENADSLQASLRPHADE----LKAKIDQNVEELKGRLTPYADEFKVKID 134 + +E +++ + + +E ++ Q + L+ R+T ++KI Sbjct: 1791 QKLLEPLEAEIQQGVNLKEEDFNKDMNEDNEGTVKELLQRGDNLQQRITDERKREEIKIK 1850 Query: 135 QTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAED 194 Q + + + + + + K ++ +Q K+ A++L + +++ ++LA L E Sbjct: 1851 QQLLQTKHNALKDLRSQRRKKALEISHQWYQYKRQADDLLKCL----DDIEKKLASLPEP 1906 Query: 195 VRGNLRGNTEGLQKSLAELGGHLDQQVEEF---RRRVEPYGENFNKALVQQMEQLRQKLG 251 ++ + E+ L ++ EE RR+ E E+ +E + +L Sbjct: 1907 RD----------ERKIKEIDRELQKKKEELNAVRRQAEGLSED---GAAMAVEPTQIQLS 1953 Query: 252 PHAGDVEG------HLSFLE-KDLRDKKFWYELED-TCPVGGLPPPVFSEQVMASMAAVL 303 ++E L+F + +R++ ED + +P +E S A L Sbjct: 1954 KRWREIESKFAQFRRLNFAQIHTVREETMMVMTEDMPLEISYVPSTYLTEITHVSQA--L 2011 Query: 304 TWALALLSA-----------FSATQARKGFWDYFSQTSGDKGRVEQIHQQKMA 345 LL+A F ++ K D Q+S GR++ IH +K A Sbjct: 2012 LEVEQLLNAPDLCAKDFEDLFKQEESLKNIKDSLQQSS---GRIDIIHSKKTA 2061
Score = 30.8 bits (68), Expect = 1.6 Identities = 57/226 (25%), Positives = 101/226 (44%), Gaps = 37/226 (16%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 ++S A + +SE + I+GR ++L QL + Q++E E + L Sbjct: 1005 EMSKKAPSEISRKYQSEFEE---------IEGRW-KKLSSQLVEHCQKLE----EQMNKL 1050 Query: 97 QASLRPHADELK---AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE 153 + ++ H LK A++D ++E L ++ K ++ Q R L Q Q Sbjct: 1051 R-KIQNHIQTLKKWMAEVDVFLKEEWPALGD-SEILKKQLKQC-----RLLVSDIQTIQP 1103 Query: 154 KLNHQLEGLTFQMKKNAE-ELKARISASAEELR-------QRLAPLAEDVRGNLRGNTEG 205 LN EG ++K AE E +R+ +EL Q++ E ++G L T Sbjct: 1104 SLNSVNEGGQ-KIKNEAEPEFASRLETELKELNTQWDHMCQQVYARKEALKGGLE-KTVS 1161 Query: 206 LQKSLAELGGHLDQQVEEFRRRVEPY--GENFNKALVQQMEQLRQK 249 LQK L+E+ + Q EE+ R Y + KA V++M++ +++ Sbjct: 1162 LQKDLSEMHEWMTQAEEEYLERDFEYKTPDELQKA-VEEMKRAKEE 1206
Score = 30.4 bits (67), Expect = 2.1 Identities = 15/57 (26%), Positives = 30/57 (52%), Gaps = 3/57 (5%) Query: 354 DDLGTKEMMEASSLTAWISVPFSRTLKDSLE---QDLNNMNKFLEKLRPLSGSEAPR 407 +D +E ++ + T W++ FS+ K +E DL + + L+ L L+G + P+ Sbjct: 8 EDCYEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPK 64
>gi|10720353|sp|O15078|CE29_HUMAN Centrosomal protein Cep290 Length = 1539 Score = 41.2 bits (95), Expect = 0.001 Identities = 53/233 (22%), Positives = 99/233 (42%), Gaps = 14/233 (6%) Query: 43 KEAVEHL--QKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASL 100 KE E L +K+E+ ++L SG G+ +L + + + +E+V REN + L+ + Sbjct: 1157 KEMCEFLKKEKAEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQREN-EQLKKAS 1215 Query: 101 RPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE 160 E A I+Q E+LK L ++ E + + E+L +L+ Sbjct: 1216 GILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTEKIIAE-NERLRKELK 1274 Query: 161 GLTFQMKK------NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELG 214 T +K N E L +++ EE +RL AE L G KS+ + Sbjct: 1275 KETDAAEKLRIAKNNLEILNEKMTVQLEETGKRL-QFAESRGPQLEGADSKSWKSIV-VT 1332 Query: 215 GHLDQQVEEFRRRVEPYGENFN--KALVQQMEQLRQKLGPHAGDVEGHLSFLE 265 + +++E + ++ K LV++ + QK+ + D+E + L+ Sbjct: 1333 RMYETKLKELETDIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILK 1385
>gi|34098465|sp|Q86UP2|KTN1_HUMAN Kinectin (Kinesin receptor) (CG-1 antigen) Length = 1357 Score = 41.2 bits (95), Expect = 0.001 Identities = 101/495 (20%), Positives = 202/495 (40%), Gaps = 80/495 (16%) Query: 23 SADQVATVMWDYFSQLSNNAKEAVEHLQKSELT---QQLK---------KTGPSGIKGRE 70 S D+ V+ D + S ++A++ K ELT QL+ K + K R Sbjct: 297 SEDEALCVV-DLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDR- 354 Query: 71 AEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK 130 +QL +++ +R V+ D + + H + + KI + +E + + + Sbjct: 355 CKQLTQEMMTEKERSNVVITRMKDRIGTLEKEH-NVFQNKIHVSYQETQ--------QMQ 405 Query: 131 VKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAP 190 +K Q E++ +A Q+ L + +L+++ SA +LRQ A Sbjct: 406 MKFQQVREQMEAEIAHLKQENGI--------LRDAVSNTTNQLESKQSAELNKLRQDYAR 457 Query: 191 LAEDVR---GNLRGNTEGLQKSLAELGG-HLDQQVEEFRRRVEPYGENFNKALVQQMEQL 246 L ++ G L+ E +QK AE L Q++E RR E + + Sbjct: 458 LVNELTEKTGKLQ--QEEVQKKNAEQAATQLKVQLQEAERRWE-----------EVQSYI 504 Query: 247 RQKLGPH-AGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTW 305 R++ H A + F+ K+ + +L DT V +Q+ + ++ Sbjct: 505 RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTL--------VSKQQLEQRLMQLMES 556 Query: 306 ALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDL----GTKEM 361 ++ + Q + D Q K +++Q H Q A+ A + ++L K+ Sbjct: 557 EQKRVNKEESLQMQ--VQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDK 614 Query: 362 MEASSLTAWISVPFSRTLKDSLEQDLNNMNKFL----EKLRPLSGSEAPRLP-----QDP 412 + + S T K+ +D+ NMN L +KL+ L+ +A Q Sbjct: 615 QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQS 674 Query: 413 VGMR----RQLQEELE-EVKARLQPY--MAEAHELVGWNLEGLRQQLKPY-TMDLMEQVA 464 V ++ R L+E+L+ E+ +++ + + + ++ + ++ L+ + D++EQ+ Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQME 734 Query: 465 LRVQELQEQLRVVGE 479 +QE E+L+ V E Sbjct: 735 KCIQEKDEKLKTVEE 749
Score = 33.5 bits (75), Expect = 0.25 Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 17/186 (9%) Query: 85 MERVLRENADSLQASLRPHADELKAKIDQN---VEELKGRLTPYADEFKVKIDQTVEELR 141 +E L+E AD + L+ ++ K+ + + +++L+ + +++KVK+D++ + ++ Sbjct: 1118 LEHKLKE-ADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIK 1176 Query: 142 RSLAPYAQDTQEKLNHQLEGLTFQMK--KNAEELKARISASAEELRQRLAPLAEDVRGNL 199 + + + QE LE L + K +N + + E+ + +VR L Sbjct: 1177 QMQSSFTSSEQE-----LERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVR-EL 1230 Query: 200 RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEG 259 + LQK L + +Q EE E K +Q E RQK+ AGD+ Sbjct: 1231 KDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNE--RQKV---AGDLHK 1285 Query: 260 HLSFLE 265 LE Sbjct: 1286 AQQSLE 1291
>gi|50400772|sp|Q8N4C6|NIN_HUMAN Ninein (hNinein) Length = 2090 Score = 41.2 bits (95), Expect = 0.001 Identities = 54/252 (21%), Positives = 105/252 (41%), Gaps = 38/252 (15%) Query: 36 SQLSNNAKEAVEHLQKSE-LTQQLKKT------------GPSGIKGREAEQLRRQLTPYA 82 S+L N E E L + E LT +L++ PS + E+ Q+ Sbjct: 481 SRLENELLENAEKLAEYENLTNKLQRNLENVLAEKFGDLDPSSAEFFLQEERLTQMRNEY 540 Query: 83 QRMERVLRENADSLQASLRPHADE-------LKAKIDQNVEELKGRLTP----------- 124 +R RVL++ D LQ+ L + + LK + VE G + P Sbjct: 541 ERQCRVLQDQVDELQSELEEYRAQGRVLRLPLKNSPSEEVEANSGGIEPEHGLGSEECNP 600 Query: 125 --YADEFKVKIDQTVEELRRSLAPYAQDTQEKLNH---QLEGLTFQMKKNAEELKARISA 179 + E ++ I+Q E+ R + + ++K+ H QL+ KK E +K R Sbjct: 601 LNMSIEAELVIEQMKEQHHRDICCLRLELEDKVRHYEKQLDETVVSCKKAQENMKQRHEN 660 Query: 180 SAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL 239 L ++++ L ++ L+G L+++ E +++ ++ + ++E + + L Sbjct: 661 ETHTLEKQISDLKNEI-AELQGQAAVLKEAHHEATCRHEEEKKQLQVKLEEEKTHLQEKL 719 Query: 240 VQQME-QLRQKL 250 Q E +L+ +L Sbjct: 720 RLQHEMELKARL 731
Score = 28.9 bits (63), Expect = 6.2 Identities = 38/195 (19%), Positives = 77/195 (39%), Gaps = 19/195 (9%) Query: 44 EAVEHLQKSELTQQLKK--TGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLR 101 + +E + +LT ++K ++ E+ +R+L ++ME ++A + Sbjct: 760 QELEQFHQEQLTSLVEKHTLEKEELRKELLEKHQRELQEGREKMETECNRRTSQIEAQFQ 819 Query: 102 PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL------RRSLAPYAQDTQEKL 155 ++ + + ++ L+GR Y E K +Q EE + L + QE L Sbjct: 820 SDCQKVTERCESALQSLEGR---YRQELKDLQEQQREEKSQWEFEKDELTQECAEAQELL 876 Query: 156 NHQLEG-------LTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 L+ LT + + + K +++ E RQ+L ED+R L Sbjct: 877 KETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVE-RQQLLQDLEDLRNVSETQQSLLSD 935 Query: 209 SLAELGGHLDQQVEE 223 + EL +++ E Sbjct: 936 QILELKSSHKRELRE 950
>gi|42558938|sp|Q8TD31|HCR_HUMAN Alpha helical coiled-coil rod protein (Putative gene 8 protein) (Pg8) Length = 782 Score = 40.4 bits (93), Expect = 0.002 Identities = 35/136 (25%), Positives = 64/136 (47%), Gaps = 17/136 (12%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEE---LKGRLTPYA 126 + E R+QL+ AQ++E+ L++ +SL ASL + + ++ EE L+ LT Sbjct: 536 QGEAERQQLSKVAQQLEQELQQTQESL-ASLGLQLEVARQGQQESTEEAASLRQELTQQQ 594 Query: 127 DEFKVKIDQTVEELRRSLAPYAQDTQEKLN-------------HQLEGLTFQMKKNAEEL 173 + + + + V E+ L DT+ +LN Q++ Q K+ ++EL Sbjct: 595 ELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQEL 654 Query: 174 KARISASAEELRQRLA 189 + + +E QRLA Sbjct: 655 RRLQEEARKEEGQRLA 670
Score = 35.8 bits (81), Expect = 0.051 Identities = 93/505 (18%), Positives = 204/505 (40%), Gaps = 62/505 (12%) Query: 25 DQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPS---GIKGREAEQLRRQLTPY 81 +Q++++ + LS+ +A E L+KS + + ++ G + REAE LR+QL+ Sbjct: 177 EQLSSLTQAHEEALSSLTSKA-EGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKT 235 Query: 82 AQRMER--VLREN-----ADSLQASLRPHADELK----AKIDQNVEELKGRLTPYADEFK 130 + +E L EN + + + + EL+ + Q+++E + L A+ + Sbjct: 236 QEDLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQ 295 Query: 131 VKIDQTV-------EELRRSLAP-------YAQDTQEKLNHQLEGL-TFQMKKNAEELKA 175 V++ EEL R + P + + Q LN E + ++ A+EL+ Sbjct: 296 VRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEH 355 Query: 176 RISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF 235 S S ++L+ ++A L E V + LQ+SL + ++ VE G Sbjct: 356 --SDSVKQLKGQVASLQEKVTSQSQEQAI-LQRSLQDKAAEVE---------VERMGAKG 403 Query: 236 NKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPP-PVFSEQ 294 + + + ++ R++ E L + + + W E G P + + Sbjct: 404 LQLELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNR 463 Query: 295 VMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQ------------ 342 + ++ V T + + Q R+ + ++Q+ ++ Sbjct: 464 LSYAVRKVHTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSA 523 Query: 343 KMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKD--SLEQDLNNMNKFLEKLRPL 400 ++ ++ G R+ G E + S + + +T + SL L + ++ Sbjct: 524 RLIQQEVGRAREQ-GEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEE 582 Query: 401 SGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKP-YTMDL 459 + S L Q + LQE++ EV+ RL+ +++ + E R+ K ++ Sbjct: 583 AASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLN---EARREHAKAVVSLRQ 639 Query: 460 MEQVALRVQELQEQLRVVGEDTKAQ 484 +++ A + +E ++LR + E+ + + Sbjct: 640 IQRRAAQEKERSQELRRLQEEARKE 664
Score = 29.6 bits (65), Expect = 3.6 Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 18/105 (17%) Query: 166 MKKNAEELKARISASAEELRQR----LAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQV 221 ++KN EE R + L Q L E+ +L EGL+KSL+ L Sbjct: 156 VRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLSSL-------- 207 Query: 222 EEFRRRVEPYGENFNKALVQ-QMEQLRQKLGPHAGDVEGHLSFLE 265 E RR GE A Q + E LR++L D+E ++ +E Sbjct: 208 -ETRRA----GEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVE 247
>gi|37537846|sp|Q9H8L6|MRN2_HUMAN Multimerin 2 precursor (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit) Length = 949 Score = 40.4 bits (93), Expect = 0.002 Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 13/118 (11%) Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 +EL A+ A +E QR+ L +DV L L +S++EL +D +++ + E Sbjct: 287 QELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEA 346 Query: 231 YGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL---------RDKKFWYELED 279 G N + L R P ++ L L+++L R+++ Y LED Sbjct: 347 PGTNGSLVLATPGAGAR----PEPDSLQARLGQLQRNLSELHMTTARREEELQYTLED 400
Score = 35.8 bits (81), Expect = 0.051 Identities = 91/419 (21%), Positives = 156/419 (37%), Gaps = 71/419 (16%) Query: 73 QLRRQLTPY---AQRMERVLRENADSLQASLRPHADELK-------------AKIDQNVE 116 QL+R L+ R E L+ + ++A+L H DE+K +K+++ VE Sbjct: 375 QLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVE 434 Query: 117 ELKGRLTPYAD------EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA 170 EL+ T + E + +++ EE+ R L Q + + + N Sbjct: 435 ELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNC 494 Query: 171 EELKARISASAEELRQRLAPLAE-----DVRGNLRGNT-EGLQKSLAELGGHLDQQVEEF 224 ++L + E R L E D R L G++ + LQ ++ + +D E Sbjct: 495 QKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEG 554 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD--KKFWYELEDTCP 282 R +A ++ Q L G ++ + ++R F LED Sbjct: 555 ERA---------RAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALR 605 Query: 283 VGGLPPPVFSEQVMASMAAVLTWAL---------ALLSAFSATQARKGFWDYFSQTSGDK 333 + +F E+V+ M+ L AL A S Q + WD + Sbjct: 606 HEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELA------ 659 Query: 334 GRVEQIHQQKMAREPAGSVR--DDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMN 391 RV + Q PA + D G +E ++ TA + +R L+ SL D+ N+ Sbjct: 660 ARVTALEQASEPPRPAEHLEPSHDAGREE----AATTALAGL--ARELQ-SLSNDVKNVG 712 Query: 392 KFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQ 450 + E +G+ A L G L L + L+ + H L G N +GL + Sbjct: 713 RCCE---AEAGAGAASLNASLDG----LHNALFATQRSLEQHQRLFHSLFG-NFQGLME 763
>gi|2501668|sp|Q13474|DRP2_HUMAN Dystrophin-related protein 2 Length = 954 Score = 38.9 bits (89), Expect = 0.006 Identities = 47/192 (24%), Positives = 87/192 (45%), Gaps = 27/192 (14%) Query: 397 LRPLSGSEAPRLPQDPVGMR---RQLQEELEEVKARLQPYMAEA-------HELVGWNLE 446 L+ L+GS P +P M +++++ ++ARL+ + + E++ W L Sbjct: 58 LKLLNGSVGASGPLEPPAMNLCWNEIKKKSHNLRARLEAFSDHSGKLQLPLQEIIDW-LS 116 Query: 447 GLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHH 506 ++L + L VAL VQ+ +E E+ K++ +++L+ Q+ + H Sbjct: 117 QKDEELSAQ-LPLQGDVAL-VQQEKETHAAFMEEVKSR----APYIYSVLESAQAFLSQH 170 Query: 507 TGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALH 566 F+EL P++ES + + +Q L R V A + L KLT + H Sbjct: 171 P--FEELEEPHSESKDTSPKQRIQNLSRFVWKQATVASE--------LWEKLTARCVDQH 220 Query: 567 ARIQQNLDQLRE 578 I++ L+QL E Sbjct: 221 RHIERTLEQLLE 232
>gi|730299|sp|P41219|PERI_HUMAN Peripherin Length = 471 Score = 38.5 bits (88), Expect = 0.008 Identities = 56/266 (21%), Positives = 112/266 (42%), Gaps = 40/266 (15%) Query: 41 NAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASL 100 N E V L++ + + + G + A+QL +Q +R +L D +Q Sbjct: 110 NFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQELRELRRELELLGRERDRVQVER 169 Query: 101 RPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE 160 A++L A + Q +EE + R A+ V + V++ S + + K+ ++ Sbjct: 170 DGLAEDLAA-LKQRLEE-ETRKREDAEHNLVLFRKDVDDATLSRL----ELERKIESLMD 223 Query: 161 GLTFQMKKNAEELK-ARISASAEELRQ---------RLAPLAEDVRG--------NLRGN 202 + F K + EEL+ ++S +++++Q L D+R NL+ Sbjct: 224 EIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRDIRAQYESIAAKNLQEA 283 Query: 203 TEGLQKSLAELGGHLD----------QQVEEFRRRVEPYG------ENFNKALVQQMEQL 246 E + A+L + Q++ E RR+++ N+AL++Q+ +L Sbjct: 284 EEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVDGLRGTNEALLRQLREL 343 Query: 247 RQKLGPHAGDVEGHLSFLEKDLRDKK 272 ++ AG + + LE++LR K Sbjct: 344 EEQFALEAGGYQAGAARLEEELRQLK 369
>gi|127234|sp|P26038|MOES_HUMAN Moesin (Membrane-organizing extension spike protein) Length = 577 Score = 38.5 bits (88), Expect = 0.008 Identities = 45/181 (24%), Positives = 79/181 (43%), Gaps = 25/181 (13%) Query: 70 EAEQLRRQLTP--YAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYAD 127 E +Q++ Q + ++MER + EN + R A++ K KI++ EEL RL + Sbjct: 301 EVQQMKAQAREEKHQKQMERAMLEN----EKKKREMAEKEKEKIEREKEELMERLKQIEE 356 Query: 128 EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR 187 + K + E+ RR+L +LE + + AE+L A+ AEE ++ Sbjct: 357 QTKKAQQELEEQTRRAL-------------ELEQERKRAQSEAEKL-AKERQEAEEAKEA 402 Query: 188 LAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR 247 L + D + E L +AEL + Q+E R++ E + + E L Sbjct: 403 LLQASRD----QKKTQEQLALEMAELTARI-SQLEMARQKKESEAVEWQQKAQMVQEDLE 457 Query: 248 Q 248 + Sbjct: 458 K 458
Score = 28.9 bits (63), Expect = 6.2 Identities = 45/210 (21%), Positives = 87/210 (41%), Gaps = 21/210 (10%) Query: 85 MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL 144 M R + + Q + ++ + ++++ + E + + A++ K KI++ EEL L Sbjct: 292 MRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERL 351 Query: 145 APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE 204 + T +K +LE T + + +E K R + AE+L + E L+ + + Sbjct: 352 KQIEEQT-KKAQQELEEQTRRALELEQERK-RAQSEAEKLAKERQEAEEAKEALLQASRD 409 Query: 205 GLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFL 264 QK E L ++ E R + Q+E RQK A + + + Sbjct: 410 --QKKTQE---QLALEMAELTAR------------ISQLEMARQKKESEAVEWQQKAQMV 452 Query: 265 EKDLRDKKFWYELEDTCPVGGLPPPVFSEQ 294 ++DL +K EL+ + P +EQ Sbjct: 453 QEDL--EKTRAELKTAMSTPHVAEPAENEQ 480
>gi|32470610|sp|Q08378|GOA3_HUMAN Golgi autoantigen, golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170) Length = 1498 Score = 37.7 bits (86), Expect = 0.013 Identities = 56/257 (21%), Positives = 114/257 (44%), Gaps = 40/257 (15%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 +++++A + L++ +LT + ++ +E L +QLT + L+ SL Sbjct: 686 RMADSAASLEQQLEQVKLTLLQRDQQLEALQ-QEHLDLMKQLT----LTQEALQSREQSL 740 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEF-KVKIDQTVEELRRSLAPYAQDTQEKL 155 A L+ H DEL+A++ EL+G D ++ ++ + E A ++ ++ Sbjct: 741 DA-LQTHYDELQARLG----ELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRG 795 Query: 156 NHQLEGLTFQMKKNAEELKARI---SASAEELRQRLAPLAEDVRG-------------NL 199 +LE T + + E+L+ + S E L+Q A L + ++ Sbjct: 796 ARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAY 855 Query: 200 RGNTEGLQKSLAELGG---HLDQQVEEFRRRV-EPYGENFN-----KALVQQMEQLRQKL 250 R + + ++EL LD +++E R+ + + +GE L +++ Q+RQ Sbjct: 856 RRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQ-- 913 Query: 251 GPHAGDVEGHLSFLEKD 267 H D+EGHL +K+ Sbjct: 914 --HMADLEGHLQSAQKE 928
Score = 31.2 bits (69), Expect = 1.3 Identities = 125/655 (19%), Positives = 252/655 (38%), Gaps = 95/655 (14%) Query: 46 VEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD 105 VEHLQ+ T LKK ++ + + L++++ A R + ++ S + R D Sbjct: 824 VEHLQQE--TAALKKQ----MQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLD 877 Query: 106 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPY------AQDTQEKLNHQL 159 ++ Q + ++ G E ++ + V ++R+ +A AQ ++++ L Sbjct: 878 SELKELRQELMQVHGEKRTAEAELS-RLHREVAQVRQHMADLEGHLQSAQKERDEMETHL 936 Query: 160 EGLTFQ-------------MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL 206 + L F +KK EEL+ + E +Q++ L D+ + + + Sbjct: 937 QSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLT-SAQKEMKTK 995 Query: 207 QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQ--------QMEQLRQKLGPHAGDVE 258 K+ G L ++++E E + Q + + Q L V Sbjct: 996 HKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVS 1055 Query: 259 GHLSFLEKDLRD------------KKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWA 306 + LEK+L++ ++ ELED F +++ + A Sbjct: 1056 HSKTLLEKELQEVIALTSQELEESREKVLELEDELQ----ESRGFRKKIKRLEESNKKLA 1111 Query: 307 LALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASS 366 L L + KG Q++ I + +A+ A V+ +L + +++ Sbjct: 1112 LEL-------EHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKE 1164 Query: 367 LTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEV 426 + L+ SLE++ +N E++ + EA + +L E +E+ Sbjct: 1165 EEDRQMKHLVQALQASLEKEKEKVNSLKEQV-AAAKVEAGHNRRHFKAASLELSEVKKEL 1223 Query: 427 KAR---LQPYMAEAHELVGWNLEGLR-QQLKPYTMDLME---QVALRVQELQEQL--RVV 477 +A+ +Q AEA +L EG Q++ + +L E Q+ L ++L EQL + V Sbjct: 1224 QAKEHLVQKLQAEADDL--QIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPV 1281 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVA 537 G L VD+ +Q L+ ++ +L + G+ + +Q + +S Sbjct: 1282 GNQEMENLKWEVDQKEREIQSLKQQL--------DLTEQQGRKELEGLQQLLQNV-KSEL 1332 Query: 538 PHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSR------------AFX 585 A + + +L K++ + +QQN QL+ +L R A Sbjct: 1333 EMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQN-QQLKLDLRRGAAKTRKEPKGEASS 1391 Query: 586 XXXXXXXXXPD---PQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 637 PD P L EE+ + A ++ + + + + QE + +Q+Q+ Sbjct: 1392 SNPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQM 1446
>gi|23822112|sp|Q9P2E9|RRB1_HUMAN Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130 related protein) Length = 1410 Score = 37.7 bits (86), Expect = 0.013 Identities = 111/500 (22%), Positives = 192/500 (38%), Gaps = 67/500 (13%) Query: 49 LQKSELTQQLKKTGPSGIKGR--EAEQLRRQLTPYAQRMERVLR----ENADSLQASLRP 102 LQ SE + K SG+ G+ EA QLT + +E +L +A +QAS + Sbjct: 922 LQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQAS-QA 980 Query: 103 HADELKAKIDQNVEELKG------RLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 AD+ + ++ + ++ G L ++ KVK + E+ +++ A ++ Sbjct: 981 EADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALAT-AEQACK 1039 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH 216 +L LT Q K+ +E+ I A E L P + + TE LQ L E G Sbjct: 1040 EKLLSLT-QAKEESEKQLCLIEAQTMEALLALLPELSVLAQ--QNYTEWLQ-DLKEKGPT 1095 Query: 217 LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYE 276 L ++ EP + +K +++ E+ + L L+ E LRD + E Sbjct: 1096 L---LKHPPAPAEPSSDLASK--LREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVE 1150 Query: 277 LEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRV 336 E+ V+ +V A+ + + + + KG + Q + Sbjct: 1151 EEEQ---------VWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHL 1201 Query: 337 EQIHQQKMAREPA---GSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSL---EQDLNNM 390 E ++ MA A ++ G ++++ S + ++ D L Q L+ M Sbjct: 1202 EAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEM 1261 Query: 391 NKFLEKL----RPLSGSEAPRLPQDPVGMRRQL---QEELEEVKARLQPYMAEAHELVGW 443 +E P S EAP QDPV ++ QL + LE+ + + Q AE E Sbjct: 1262 KSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEE---- 1317 Query: 444 NLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG--EDTKAQLLGGVDEAWALLQGLQS 501 + A R+QE E+LR G E ++ + + E + L S Sbjct: 1318 ----------------AQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTS 1361 Query: 502 RVVHHTGRFKELFHPYAESL 521 + R +EL E L Sbjct: 1362 DLGRAATRLQELLKTTQEQL 1381
Score = 34.3 bits (77), Expect = 0.15 Identities = 101/456 (22%), Positives = 171/456 (37%), Gaps = 77/456 (16%) Query: 24 ADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTG--PSGIKGREAEQLRRQ---- 77 ADQ T + + SQ+S KEA+E L+++ Q++K K EA Q Sbjct: 982 ADQQQTRLKELESQVSGLEKEAIE-LREAVEQQKVKNNDLREKNWKAMEALATAEQACKE 1040 Query: 78 ----LTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEE------------LKGR 121 LT + E+ L +L EL QN E LK Sbjct: 1041 KLLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHP 1100 Query: 122 LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE----LKARI 177 P + E +S D + + EG+ ++K+ EE +A++ Sbjct: 1101 PAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKV 1160 Query: 178 SASAEELRQRLAPL--AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF 235 A+ EEL++ + E++ L+G E + E HL+ ++E+ +N+ Sbjct: 1161 GAAEEELQKSRVTVKHLEEIVEKLKGELES-SDQVREHTSHLEAELEKHMAAASAECQNY 1219 Query: 236 NK---ALVQQMEQLRQKLGPHAGDVE---GHLSFLEKDLRDKKFWYELEDTCPVGGLP-- 287 K L Q + + + +L + + L+ + + L + K E D + G P Sbjct: 1220 AKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGD---IAGAPAS 1276 Query: 288 ----PPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQK 343 PP +EQ + L W A+L TQ +K F + R+++ ++ Sbjct: 1277 SPEAPP--AEQDPVQLKTQLEWTEAILED-EQTQRQK-LTAEFEEAQTSACRLQEELEKL 1332 Query: 344 MAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGS 403 P L + E EAS LK+ LE++ +KL G Sbjct: 1333 RTAGP-------LESSETEEASQ------------LKERLEKE--------KKLTSDLGR 1365 Query: 404 EAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHE 439 A RL + + QL E + VK +LQ + +A + Sbjct: 1366 AATRLQELLKTTQEQLAREKDTVK-KLQEQLEKAED 1400
>gi|1345731|sp|P49454|CENPF_HUMAN CENP-F kinetochore protein (Centromere protein F) (Mitosin) (AH antigen) Length = 3210 Score = 37.4 bits (85), Expect = 0.017 Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 27/217 (12%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 QL NN +E + L ++E Q + + ++ R E+++++ E+ RE L Sbjct: 448 QLENNLEEFKQKLCRAEQAFQASQIKENELR-RSMEEMKKENNLLKSHSEQKAREVCH-L 505 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 +A L+ N+++ + +A+E K K LR D QEK+N Sbjct: 506 EAELK------------NIKQCLNQSQNFAEEMKAKNTSQETMLR--------DLQEKIN 545 Query: 157 HQLEGLTFQ-MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG 215 Q LT + +K +L+ + S + L++R + E + L TE K+L Sbjct: 546 QQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI-EQLNDKL-SKTEKESKALLSALE 603 Query: 216 HLDQQVEEFRRRVEPYG--ENFNKALVQQMEQLRQKL 250 ++ EE + + ++ N+ L+ QME ++ L Sbjct: 604 LKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENL 640
Score = 35.8 bits (81), Expect = 0.051 Identities = 103/437 (23%), Positives = 162/437 (37%), Gaps = 72/437 (16%) Query: 89 LRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYA 148 LR + L+ +R ADE K E+LK R D K K++ EL+ S Sbjct: 2213 LRRGIEKLR--VRIEADEKKQL--HIAEKLKEREREN-DSLKDKVENLERELQMS----- 2262 Query: 149 QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 ++ QE + E K E LK +I A L+ L LR E L K Sbjct: 2263 EENQELVILDAEN----SKAEVETLKTQIEEMARSLKVFELDLV-----TLRSEKENLTK 2313 Query: 209 SLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL 268 + E G Q+ E + + + K+L+++ EQ ++ + L K+L Sbjct: 2314 QIQEKQG----QLSELDKLLSSF-----KSLLEEKEQAEIQIKEESKTAVEMLQNQLKEL 2364 Query: 269 R--------DKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARK 320 D++ E + L PP+ E + + L A L A Q Sbjct: 2365 NEAVAALCGDQEIMKATEQS-----LDPPIEEEHQLRNSIEKLR---ARLEADEKKQLCV 2416 Query: 321 GFWDYFSQTSGD--KGRVEQI------------HQQKMAREPAGSVRDDLGTKEMMEASS 366 S+ D KGRVE + H A G V E M S Sbjct: 2417 LQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSL 2476 Query: 367 LTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEV 426 + V R+ K+ L +L + + +L ++ S + +E E+ Sbjct: 2477 RGLELDVVTIRSEKEDLTNELQKEQERISELEIINSSF------------ENILQEKEQE 2524 Query: 427 KARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLL 486 K +++ + A E++ L+ L +++ D E + Q L Q+ + E KAQLL Sbjct: 2525 KVQMKEKSSTAMEMLQTQLKELNERVAALHND-QEACKAKEQNLSSQVECL-ELEKAQLL 2582 Query: 487 GGVDEAWALLQGLQSRV 503 G+DEA LQS V Sbjct: 2583 QGLDEAKNNYIVLQSSV 2599
Score = 30.8 bits (68), Expect = 1.6 Identities = 43/238 (18%), Positives = 93/238 (39%), Gaps = 44/238 (18%) Query: 403 SEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLME- 461 S +P L ++L+ ++ E++ RLQ + E V + L+ QL+ ++L+E Sbjct: 274 SSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVN-KFQELQLQLEKAKVELIEK 332 Query: 462 -------------------QVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSR 502 Q + + L+++L+ + ED Q +L Q ++ + Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEK 392 Query: 503 ---VVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLT 559 R + F + + R QEL ++ H VL +L Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMH------------NVLQAELD 440 Query: 560 LKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYL 617 K ++ +++ NL++ +++L RA Q+ E+R+ ++ +++ L Sbjct: 441 -KLTSVKQQLENNLEEFKQKLCRAEQAFQAS-------QIKENELRRSMEEMKKENNL 490
>gi|119862|sp|P06734|FCER2_HUMAN Low affinity immunoglobulin epsilon Fc receptor (Lymphocyte IgE receptor) (Fc-epsilon-RII) (CD23 antigen) (BLAST-2) (Immunoglobulin E-binding factor) Length = 321 Score = 37.4 bits (85), Expect = 0.017 Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 16/111 (14%) Query: 376 SRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMA 435 +++LK E+ N+++ + L G + + Q Q+ +ELEE++A Q + Sbjct: 50 TQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQST-----QISQELEELRAEQQRLKS 104 Query: 436 EAHELVGWNLEGLRQQLKPY----------TMDLMEQVALRVQELQEQLRV 476 + EL WNL GL+ L + DL+E++ V +L+ +L+V Sbjct: 105 QDLEL-SWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQV 154
>gi|33302627|sp|Q15643|TRIPB_HUMAN Thyroid receptor interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution related gene on chromosome 14) Length = 1979 Score = 37.4 bits (85), Expect = 0.017 Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 34/244 (13%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 QL+ ++ +E + +L + K PS +K + + ++ + +E V R L Sbjct: 338 QLNVEKRQIMEECENLKL--ECSKLQPSAVKQSDTMTEKERILAQSASVEEVFR-----L 390 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 Q +L +E+ N + D K+K+ V E +SL L+ Sbjct: 391 QQALSDAENEIMRLSSLNQDNSLAE-----DNLKLKMRIEVLEKEKSL----------LS 435 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH 216 + E L + K E + S + ++ L D+R NL + L +S++E Sbjct: 436 QEKEELQMSLLKLNNEYEVIKSTATRDIS--LDSELHDLRLNLEAKEQELNQSISEKET- 492 Query: 217 LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD-KKFWY 275 L ++EE R+ N+ + M ++ +L + + +S L++DL D KK + Sbjct: 493 LIAEIEELDRQ--------NQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVH 544 Query: 276 ELED 279 +LED Sbjct: 545 QLED 548
Score = 28.5 bits (62), Expect = 8.1 Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 29/192 (15%) Query: 100 LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL 159 + P Q+ E L+ + E + Q +EELR+SL QEK Sbjct: 1312 ISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSL-------QEK----- 1359 Query: 160 EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAE----LGG 215 + +++N L I+A++E R+ +++ L+ + LQK L E + Sbjct: 1360 DATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIK-QLKEKQDVLQKLLKEKDLLIKA 1418 Query: 216 HLDQQV---EEFRRRVEPYGENFNKALVQQMEQLRQK---LGPHAGDVEGHLSFLEKDLR 269 DQ + E F +V N N+ L Q + L+++ L G ++G + + R Sbjct: 1419 KSDQLLSSNENFTNKV-----NENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYR 1473 Query: 270 DKKFWYE-LEDT 280 K+ Y+ L++T Sbjct: 1474 GKETEYQALQET 1485
>gi|29337005|sp|Q9UQE7|SMC3_HUMAN Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) Length = 1217 Score = 37.0 bits (84), Expect = 0.023 Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 35/187 (18%) Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE 171 +Q + E + +L DE K +T E R L QD ++K+ +++ Sbjct: 229 NQELNETRAKL----DELSAK-RETSGEKSRQLRDAQQDARDKME--------DIERQVR 275 Query: 172 ELKARISASAEELRQ-------------RLAPLAEDVRGNLRGNTEGLQKSLAELGGHLD 218 ELK +ISA EE Q +L A+D++ L GN+E ++ L E L Sbjct: 276 ELKTKISAMKEEKEQLSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKE-RQKLL 334 Query: 219 QQVEEFRRRVEPYGENFN-------KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK 271 +++EE ++ + FN + + + + +++ +A G F K+ RDK Sbjct: 335 EKIEEKQKELAETEPKFNSVKEKEERGIARLAQATQERTDLYAKQGRGS-QFTSKEERDK 393 Query: 272 KFWYELE 278 EL+ Sbjct: 394 WIKKELK 400
>gi|41688595|sp|Q9UJC3|HOOK1_HUMAN Hook homolog 1 (h-hook1) (hHK1) Length = 728 Score = 37.0 bits (84), Expect = 0.023 Identities = 44/193 (22%), Positives = 83/193 (43%), Gaps = 26/193 (13%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 Q + E +E LQ+ +L Q+ +K + R +++ R+L + +++ L+E Sbjct: 480 QQEGSENERIEELQE-QLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKS 538 Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 + E +K+ Q +E +LT +E + K +EL L P +K+N Sbjct: 539 EG-------ESSSKLKQKLEAHMEKLTEVHEELQKK-----QELIEDLQPDINQNVQKIN 586 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH 216 L ++K E++KA + +R E R ++ L + AE+ Sbjct: 587 E----LEAALQKKDEDMKA--------MEERYKMYLEKARNVIKTLDPKLNPASAEI-ML 633 Query: 217 LDQQVEEFRRRVE 229 L +Q+ E RR+E Sbjct: 634 LRKQLAEKERRIE 646
>gi|2501084|sp|Q16623|STX1A_HUMAN Syntaxin-1A (Neuron-specific antigen HPC-1) Length = 288 Score = 37.0 bits (84), Expect = 0.023 Identities = 35/149 (23%), Positives = 63/149 (42%), Gaps = 26/149 (17%) Query: 87 RVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SL 144 R +++ D ++ D + + VEE++G F KI + VEE++R S Sbjct: 9 RTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRG--------FIDKIAENVEEVKRKHSA 60 Query: 145 APYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTE 204 + + EK +LE L +KK A ++++++ + + + Q E Sbjct: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQE----------------E 104 Query: 205 GLQKSLAELGGHLDQQVEEFRRRVEPYGE 233 GL +S A+L Q R+ VE E Sbjct: 105 GLNRSSADLRIRKTQHSTLSRKFVEVMSE 133
>gi|30912698|sp|Q8NB25|CF60_HUMAN Hypothetical protein C6orf60 Length = 1020 Score = 36.6 bits (83), Expect = 0.030 Identities = 29/137 (21%), Positives = 57/137 (41%) Query: 115 VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK 174 +EE + L + Q + EL + + + QE +L+ L ++++ +L Sbjct: 297 LEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLN 356 Query: 175 ARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGEN 234 S + EEL + E V N + + LQ L E +EE + +++ EN Sbjct: 357 EAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELEN 416 Query: 235 FNKALVQQMEQLRQKLG 251 + L ++ Q++G Sbjct: 417 LKEVLEDKLNTANQEIG 433
Score = 34.7 bits (78), Expect = 0.11 Identities = 47/237 (19%), Positives = 100/237 (42%), Gaps = 24/237 (10%) Query: 40 NNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQAS 99 N A + + HLQ + + G+ AE L L +R++ L DSL+ + Sbjct: 426 NTANQEIGHLQ------DMVRKSEQGLGS--AEGLIASLQDSQERLQNELDLTKDSLKET 477 Query: 100 LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL 159 + ++ +++Q ++ + + +E K+K+D+ +L + KL +L Sbjct: 478 -KDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREEL 536 Query: 160 EGLTFQMKKNAE----ELKARISASA--------EELRQRLAPLAEDVRGNLRGNTEGLQ 207 + KK+A +LK R +A E+L +++ L +++ L + LQ Sbjct: 537 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQ 596 Query: 208 KSLAEL---GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL 261 + A+ L Q++EE + + ++ +A V + + ++ +E HL Sbjct: 597 QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 653
>gi|125962|sp|P02545|LAMA_HUMAN Lamin A/C (70 kDa lamin) Length = 664 Score = 36.2 bits (82), Expect = 0.039 Identities = 32/161 (19%), Positives = 73/161 (45%), Gaps = 10/161 (6%) Query: 71 AEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK 130 +E+LR + R+ + ++ L EL+A+ + VE+ K L + Sbjct: 212 SEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKEL---EKTYS 268 Query: 131 VKIDQTVEELRR--SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL 188 K+D + R +L A + ++ +++ L+ Q+ +L+ +++A +LR Sbjct: 269 AKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQL----SQLQKQLAAKEAKLRDLE 324 Query: 189 APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVE 229 LA + R R ++ +AE+ + QQ++E++ ++ Sbjct: 325 DSLARE-RDTSRRLLAEKEREMAEMRARMQQQLDEYQELLD 364
>gi|47117086|sp|P61266|STX1C_HUMAN Syntaxin-1B2 Length = 288 Score = 36.2 bits (82), Expect = 0.039 Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 26/141 (18%) Query: 91 ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SLAPYA 148 +++D + + D + + VEE++G + K+ + VE++++ S A Sbjct: 12 KDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIE--------KLSEDVEQVKKQHSAILAA 63 Query: 149 QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 + EK +LE LT +KK A ++++++ A + + Q EGL + Sbjct: 64 PNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQE----------------EGLNR 107 Query: 209 SLAELGGHLDQQVEEFRRRVE 229 S A+L Q R+ VE Sbjct: 108 SSADLRIRKTQHSTLSRKFVE 128
>gi|51827892|sp|Q8IUD2|ERC1_HUMAN ERC protein 1 (ELKS protein) Length = 1116 Score = 36.2 bits (82), Expect = 0.039 Identities = 51/229 (22%), Positives = 96/229 (41%), Gaps = 39/229 (17%) Query: 53 ELTQQLKKTGPSGIKGREA-------EQLRRQLTPYAQRMERVLRENADSLQASLRPHAD 105 ++ QLKK + ++ R + + L R++T Y + E D L L+ + Sbjct: 712 KMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAE-VDRLLEILKEVEN 770 Query: 106 ELKAKIDQNVEELKGRLTPYADEF----------KVKIDQTVEELRR------SLAPYAQ 149 E K D+ + EL+ ++ + K K Q +EE RR + Q Sbjct: 771 EKNDK-DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQ 829 Query: 150 DTQEKLNHQLEGLTFQMKKN-----------AEELKARISAS--AEELRQRLAPLAEDVR 196 D+ K + ++E L ++++ A+E AR +A EEL + + +++ Sbjct: 830 DSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELE 889 Query: 197 GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 245 +++ Q+SLAE HL E R+ +E E +AL+ + + Sbjct: 890 -SMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE 937
>gi|23831094|sp|O00291|HIP1_HUMAN Huntingtin interacting protein 1 (HIP-I) Length = 1030 Score = 36.2 bits (82), Expect = 0.039 Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%) Query: 134 DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE 193 D +E L R ++ E + + + + Q+K + EL+A + A + LRQ+ A E Sbjct: 367 DHLIERLYREISGLKAQL-ENMKTESQRVVLQLKGHVSELEADL-AEQQHLRQQAADDCE 424 Query: 194 DVRGNL------RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLR 247 +R L R +TE Q+SL+E+ + + + E Y E LVQ L Sbjct: 425 FLRAELDELRRQREDTEKAQRSLSEIERKAQANEQRYSKLKEKYSE-----LVQNHADLL 479 Query: 248 QK 249 +K Sbjct: 480 RK 481
>gi|32699565|sp|Q8IUG5|MY18B_HUMAN Myosin XVIIIB (Myosin 18B) Length = 2567 Score = 36.2 bits (82), Expect = 0.039 Identities = 96/440 (21%), Positives = 168/440 (38%), Gaps = 76/440 (17%) Query: 67 KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL---KAKIDQNVEELKG--- 120 K E LRR+L ++++ LR+N D L++ + +L + K D + L+ Sbjct: 1407 KEEELTTLRRKLEK-SEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERA 1465 Query: 121 -RLTPYAD--EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARI 177 RL + + E K K +Q ++L + ++ Q+K+ QL L A+E + R Sbjct: 1466 ERLQAFREVQELKSKHEQVQKKLG-DVNKQLEEAQQKI--QLNDLERNPTGGADEWQMRF 1522 Query: 178 SASAEE---LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGEN 234 + E LR+RL E + L E L++ L EL D Sbjct: 1523 DCAQMENEFLRKRLQQCEERLDSELTARKE-LEQKLGELQSAYD---------------- 1565 Query: 235 FNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK--------DLRDKKFWYELEDTCPVGGL 286 + QL++K D+E LE + + KKF +L L Sbjct: 1566 ---GAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQA-----L 1617 Query: 287 PPPVFSEQVMASMAAVLT---WALALLSAFSATQARKGFWDYFSQTSGDKGRVEQI--HQ 341 VF + + + T W L Q ++ + S K +VE + H+ Sbjct: 1618 GESVFEKGLREKVTQENTSVRWELG--------QLQQQLKQKEQEASQLKQQVEMLQDHK 1669 Query: 342 QKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLS 401 +++ P+ G KE + W + S + ++ N K LE+LR Sbjct: 1670 RELLGSPSLGENCVAGLKERL-------W-KLESSALEQQKIQSQQENTIKQLEQLRQRF 1721 Query: 402 GSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGL------RQQLKPY 455 E R+ Q R +EELE+V+ Q + + + E +Q L+ Sbjct: 1722 ELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGL 1781 Query: 456 TMDLMEQVALRVQELQEQLR 475 L +Q+ R +++++LR Sbjct: 1782 IGTLCDQIGHRDFDVEKRLR 1801
Score = 33.1 bits (74), Expect = 0.33 Identities = 37/179 (20%), Positives = 79/179 (44%), Gaps = 23/179 (12%) Query: 53 ELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENA--DSLQASLRPHADELKAK 110 +L QQLK+ K +EA QL++Q+ +L + ++ A L+ +L++ Sbjct: 1643 QLQQQLKQ------KEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESS 1696 Query: 111 I--DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK 168 Q ++ + ++ + + + +E +++ +D +E +LE + +K Sbjct: 1697 ALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEE----ELEDVRQSCQK 1752 Query: 169 NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR 227 +L+ ++ EE + L + + + EGL +L + GH D VE+ RR Sbjct: 1753 RLHQLEMQLEQEYEEKQMVL---------HEKQDLEGLIGTLCDQIGHRDFDVEKRLRR 1802
>gi|13123943|sp|O43707|ACTN4_HUMAN Alpha-actinin 4 (Non-muscle alpha-actinin 4) (F-actin cross linking protein) Length = 911 Score = 35.8 bits (81), Expect = 0.051 Identities = 52/244 (21%), Positives = 94/244 (38%), Gaps = 55/244 (22%) Query: 32 WDYFSQLSNNAKEAVEHLQKS-ELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR 90 WD L+++ +EA+E +K E QL + ++ P+ ME + Sbjct: 502 WDALGSLTHSRREALEKTEKQLEAIDQLHL------------EYAKRAAPFNNWMESAME 549 Query: 91 ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA----- 145 + D I +EE++G ++ + D+FK + E LA Sbjct: 550 DLQDMF--------------IVHTIEEIEGLISAH-DQFKSTLPDADREREAILAIHKEA 594 Query: 146 ---------------PYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS--ASAEELRQRL 188 PY T + +N + E + + K L S S E LR++ Sbjct: 595 QRIAESNHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQF 654 Query: 189 APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQ---VEEFRRRVEPYGENFNKALVQQMEQ 245 A A V ++ E + + E+ G L+ Q ++++ R + Y N + L++Q Q Sbjct: 655 ASQANVVGPWIQTKMEEIGRISIEMNGTLEDQLSHLKQYERSIVDYKPNLD--LLEQQHQ 712 Query: 246 LRQK 249 L Q+ Sbjct: 713 LIQE 716
>gi|30173386|sp|Q9NTJ3|SMC4_HUMAN Structural maintenance of chromosomes 4-like 1 protein (Chromosome-associated polypeptide C) (hCAP-C) (XCAP-C homolog) Length = 1288 Score = 35.8 bits (81), Expect = 0.051 Identities = 61/272 (22%), Positives = 110/272 (40%), Gaps = 46/272 (16%) Query: 36 SQLSNNAKEAVE-HLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRM---ERVLRE 91 SQL N++K+A++ QK +L +++ K S RE + T QR+ E L Sbjct: 781 SQLQNDSKKAMQIQEQKVQLEERVVKLRHSE---REMRNTLEKFTASIQRLIEQEEYLNV 837 Query: 92 NADSLQASLRPHADELKAK--IDQNVEELKGRLTPYAD-----EFKVK-IDQTVEELRRS 143 L+A++ A + K + +++NV K A+ E +VK + T+ E+ Sbjct: 838 QVKELEANVLATAPDKKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNTIVEINNH 897 Query: 144 LAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA-----------------RISASAEELRQ 186 QD +K+N QL+ + K +K I + +E+ Sbjct: 898 KLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKDTEKEVDD 957 Query: 187 RLAPL--AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME 244 A L ED + NT ++SL E + ++ + ++ EN AL + Sbjct: 958 LTAELKSLEDKAAEVVKNTNAAEESLPE----IQKEHRNLLQELKVIQEN-EHALQKDAL 1012 Query: 245 QLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYE 276 ++ KL G + H S + K+W++ Sbjct: 1013 SIKLKLEQIDGHIAEHNSKI-------KYWHK 1037
>gi|29336622|sp|Q14683|SMC1A_HUMAN Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (SB1.8/DXS423E protein) (Sb1.8) Length = 1233 Score = 35.4 bits (80), Expect = 0.066 Identities = 50/213 (23%), Positives = 89/213 (41%), Gaps = 37/213 (17%) Query: 42 AKEAVEH-LQKSELTQQLKKTGPSGIKGREAE--QLRRQLTPYA---QRMERVLRENADS 95 AKE H ++K E ++ + K R+ + +L +++ Q E + E + S Sbjct: 301 AKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQS 360 Query: 96 LQASLRPHADELKAKIDQNVEELKGRLTPYADEF-KVKIDQTVEELRRSLAPYAQ-DTQE 153 L +++K K + EE R A E K DQ ++ R L + +T+ Sbjct: 361 QGRDLTLEENQVK-KYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEA 419 Query: 154 KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL 213 K+ +L + + +K E+L+ I+ S + L ++ +L Sbjct: 420 KIKQKLREIE-ENQKRIEKLEEYITTSKQSLEEQ-----------------------KKL 455 Query: 214 GGHLDQQVEEFRRRVEPYGENFNKALVQQMEQL 246 G L ++VE +RR+ + NK L Q MEQL Sbjct: 456 EGELTEEVEMAKRRI----DEINKELNQVMEQL 484
>gi|399227|sp|Q02224|CENPE_HUMAN Centromeric protein E (CENP-E protein) Length = 2663 Score = 35.4 bits (80), Expect = 0.066 Identities = 120/686 (17%), Positives = 255/686 (37%), Gaps = 127/686 (18%) Query: 42 AKEAVEHLQKSELTQQLKKTGPSGIKGRE-AEQLRRQLTPYAQRMERVLRENADSLQASL 100 A+ +E L+ +E Q+ ++ S K R+ + ++ L +++ +RE +Q S Sbjct: 1324 ARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQ 1383 Query: 101 RPHADELKAKIDQNVEELKGRLTPYADEFKVK-------------IDQTVEELRRSLAPY 147 L K N ++ ++FK K + + ++E + Sbjct: 1384 SKQEQSLNMKEKDNETT---KIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSV 1440 Query: 148 AQ--DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE------DVRGNL 199 A+ D ++L L+ + Q+K+N +E+ A+ + EEL+ L E ++R NL Sbjct: 1441 AKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL 1500 Query: 200 ---RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYG--------ENFNKALVQQMEQLRQ 248 +QK L + L +++E + E EN N+ ++Q ++ R+ Sbjct: 1501 SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNE--LKQFKEHRK 1558 Query: 249 KLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALA 308 +E + L L++ + ++ + ++ M + L Sbjct: 1559 AKDSALQSIESKMLELTNRLQESQEEIQI-----------MIKEKEEMKRVQEAL----- 1602 Query: 309 LLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLT 368 Q ++ + ++ + + Q + E + + KE E L Sbjct: 1603 ---QIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN 1659 Query: 369 ----AWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQL----- 419 ++ ++ L ++LE ++ ++ K + LR + + Q +R + Sbjct: 1660 LENIETENIRLTQILHENLE-EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE 1718 Query: 420 -QEELEEVKARLQPYMAEAHELVG-------------WNLEGLRQQLKPYTMDLMEQVAL 465 QEEL+ V L+ + +L G +LE LK + + E++ + Sbjct: 1719 KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRI 1778 Query: 466 RVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYA--ESLVS 523 L+EQ ++T +L G V E L +Q + + + +E E + Sbjct: 1779 AHMHLKEQ-----QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833 Query: 524 GIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLK---------AKALHARIQQ--- 571 + + V E + V+ Q+ + LTL A+ LH +++ Sbjct: 1834 TLKKDVNETQKKVSEMEQLKK-------QIKDQSLTLSKLEIENLNLAQELHENLEEMKS 1886 Query: 572 ------NL-----------DQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQ- 613 NL DQL+E L +MLS+E ++ + R+ Sbjct: 1887 VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1946 Query: 614 --DTYLQIAAFTRAIDQETEEVQQQL 637 + +QI+ + +D+ +E+Q+++ Sbjct: 1947 ISEKTIQISDIQKDLDKSKDELQKKI 1972
>gi|2501085|sp|Q15531|STX1B_HUMAN Syntaxin-1B1 (Syntaxin 1B) Length = 288 Score = 35.4 bits (80), Expect = 0.066 Identities = 22/99 (22%), Positives = 48/99 (48%), Gaps = 10/99 (10%) Query: 90 RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR--SLAPY 147 R N+D + + D + + EE++G + K+ + VE++++ S Sbjct: 11 RRNSDDKEEVVHVDRDHFMDEFFEQEEEIRGCIE--------KLSEDVEQVKKQHSAILA 62 Query: 148 AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ 186 A + E+ +LE LT +KK A ++++++ A + + Q Sbjct: 63 APNPDERTKQELEDLTADIKKTANKVRSKLKAIEQSIEQ 101
>gi|14194461|sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9 (Protein kinase A anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120 like protein) (Hyperion protein) (Yotiao protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) Length = 3911 Score = 35.4 bits (80), Expect = 0.066 Identities = 78/391 (19%), Positives = 153/391 (39%), Gaps = 39/391 (9%) Query: 50 QKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKA 109 QK E T+ LK + E + R QL + E V+ AD K Sbjct: 1897 QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADE------------KT 1944 Query: 110 KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKN 169 ++ ++E K + ++ + ++EL Q+ +E L+ Q E MK Sbjct: 1945 LFERQIQE-KTDIIDRLEQELLCASNRLQELEAE-QQQIQEERELLSRQKEA----MKAE 1998 Query: 170 AEELKARISASAEELRQRLAPL---AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR 226 A ++ ++ E+L + + AE VR +L+ + L+ + E + +E Sbjct: 1999 AGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNT 2058 Query: 227 RVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGL 286 + + N+AL +Q+E++R+ L A D E +++++ +LE V Sbjct: 2059 ELMDLRQQ-NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ------KLEQQLKVVPR 2111 Query: 287 PPPVFSEQV-----MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQ 341 P+ Q +A+ T + L S Q ++ + + + RV ++ Q Sbjct: 2112 FQPISEHQTREVEQLANHLKEKTDKCSEL-LLSKEQLQRDIQERNEEIEKLEFRVRELEQ 2170 Query: 342 QKMAREPAGSVRDDLGTKEMMEAS-SLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPL 400 + +D +EA L+ + + R D E+++ N+ + LE+ R Sbjct: 2171 ALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFR-- 2228 Query: 401 SGSEAPRLPQDPVGMRRQLQEELEEVKARLQ 431 E ++ + QL+ + +E RLQ Sbjct: 2229 --EELENKNEEVQQLHMQLEIQKKESTTRLQ 2257
Score = 30.0 bits (66), Expect = 2.8 Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 11/142 (7%) Query: 115 VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK 174 +++L ++T + K+ D V E + L + E L E +K+N EE Sbjct: 2306 IDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQE----CVKRNREEEI 2361 Query: 175 ARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG------HLDQQVEEFRRRV 228 +++ E+L+Q LA + + N +E +L L+QQVE + Sbjct: 2362 EQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEM 2421 Query: 229 EPYGENFNKALVQQMEQLRQKL 250 + +N K +M QL Q+L Sbjct: 2422 -TFMKNVLKETNFKMNQLTQEL 2442
>gi|26400672|sp|Q96F44|TRI11_HUMAN Tripartite motif protein 11 (RING finger protein 92) (BIA1 protein) Length = 468 Score = 35.4 bits (80), Expect = 0.066 Identities = 36/136 (26%), Positives = 68/136 (50%), Gaps = 14/136 (10%) Query: 100 LRPHADELKAKIDQNVEELKGRL------TPYADEFKVKIDQTVEELRRSLAPYAQDTQE 153 L+ A++LKAK+++++E L+ ++ ADE V + VE R+++ + + Sbjct: 128 LQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRR 187 Query: 154 KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAEL 213 L + + L ++++ E+ R+ A L Q+ A LAE + L G + L L Sbjct: 188 LLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELI-AELEGRCQ-----LPAL 241 Query: 214 GGHLDQQVEEFRRRVE 229 G L Q +++ RRV+ Sbjct: 242 G--LLQDIKDALRRVQ 255
Score = 35.4 bits (80), Expect = 0.066 Identities = 37/129 (28%), Positives = 53/129 (41%), Gaps = 5/129 (3%) Query: 142 RSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRG 201 R L A+D + KL LE L QM+ A A+E + E R N+ G Sbjct: 126 RPLQDAAEDLKAKLEKSLEHLRKQMQD-----ALLFQAQADETCVLWQKMVESQRQNVLG 180 Query: 202 NTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL 261 E L++ LAE L Q++EE V P L QQ L + + G + Sbjct: 181 EFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPA 240 Query: 262 SFLEKDLRD 270 L +D++D Sbjct: 241 LGLLQDIKD 249
>gi|42558942|sp|O75334|LPA2_HUMAN Liprin-alpha 2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 2) (PTPRF-interacting protein alpha 2) Length = 1257 Score = 35.4 bits (80), Expect = 0.066 Identities = 86/402 (21%), Positives = 149/402 (37%), Gaps = 60/402 (14%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRPHAD----------ELKAKIDQNVEELKGR 121 EQL + R+ LRE +SL + + D +L + + Q++E L G Sbjct: 32 EQLMVNMLDERDRLLDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGG 91 Query: 122 LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA 181 L + +EL + +E +L+ + E L+ +S Sbjct: 92 LAGSKGADPPEFAALTKELNACREQLLEKEEEI--SELKAERNNTRLLLEHLECLVSRHE 149 Query: 182 EELRQRLAPLAEDVRGNLRGNTEGLQ--KSLAELGGHLDQQVEEFRR----RVEPYGENF 235 LR + + E L+ KSL E LD++V E R RV E Sbjct: 150 RSLRMTVVKRQAQSPSGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEEL 209 Query: 236 ---NKALVQQMEQ---LRQKLGPHAGDVEG-HLSFLEKDLRDKKFWYELEDTCPVGGLPP 288 N+ +V EQ +++K+ G E HL +E + E G + Sbjct: 210 AAANQEIVALREQNVHIQRKMASSEGSTESEHLEGMEPGQKVH------EKRLSNGSIDS 263 Query: 289 PVFSEQV--MASMAAVLTWALALLSA-FSATQARKGFWDYFSQTSGDKGRVEQIHQQKMA 345 + Q+ + + + +A + +A +R G + ++T+ R + I ++M Sbjct: 264 TDETSQIVELQELLEKQNYEMAQMKERLAALSSRVGEVEQEAETA----RKDLIKTEEMN 319 Query: 346 REPAGSVRDDLGTKEMMEASSLTA---WISVPFSRT----LKDSLEQDLNNMNKFLEKLR 398 + +R+ + KE ME T ++S T + D LE +L N L ++ Sbjct: 320 TKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQME 379 Query: 399 PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHEL 440 + RQLQE LE + +LQ M +A L Sbjct: 380 EKN---------------RQLQERLELAEEKLQQTMRKAETL 406
>gi|547750|sp|P35900|K1CT_HUMAN Keratin, type I cytoskeletal 20 (Cytokeratin 20) (K20) (CK 20) (Protein IT) Length = 424 Score = 35.0 bits (79), Expect = 0.087 Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 26/171 (15%) Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 Q+ E + ++N + L+ ++ N EELKG + + ELRR Sbjct: 244 QKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKG------------TEVQLTELRR 291 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE---DVRGNL 199 + +Q + +L L + ++ EE KAR S+ L+ L+ L +R N+ Sbjct: 292 T----SQSLEIELQSHL-SMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNM 346 Query: 200 -RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 R N E L ++ L+Q++ +RR +E GE+ K Q+ L ++ Sbjct: 347 ERQNNE--YHILLDIKTRLEQEIATYRRLLE--GEDV-KTTEYQLSTLEER 392
>gi|32470611|sp|Q08379|GOA2_HUMAN Golgi autoantigen, golgin subfamily A member 2 (Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95) Length = 990 Score = 35.0 bits (79), Expect = 0.087 Identities = 44/201 (21%), Positives = 92/201 (45%), Gaps = 17/201 (8%) Query: 62 GPSGIKGR---EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL-----KAKIDQ 113 GPS ++ + EAE LR++L A +++ +++N + L R + L A++ Sbjct: 445 GPSEVEQQLQAEAEHLRKELEGLAGQLQAQVQDN-EGLSRLNREQEERLLELERAAELWG 503 Query: 114 NVEELKGRLTPYADEFKVKIDQTV---EELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA 170 E + ++ + I + + EL+ LA + N +E +T + ++ Sbjct: 504 EQAEARRQILETMQNDRTTISRALSQNRELKEQLAELQSGFVKLTNENME-ITSAL-QSE 561 Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 + +K + EL+++L+ L E V + + LQ+ + GHL Q V +++ Sbjct: 562 QHVKRELGKKLGELQEKLSELKETVELKSQ-EAQSLQQQRDQYLGHLQQYVAAYQQLTSE 620 Query: 231 YGENFNKALVQQ--MEQLRQK 249 N+ L+Q ++QL+Q+ Sbjct: 621 KEVLHNQLLLQTQLVDQLQQQ 641
Score = 33.1 bits (74), Expect = 0.33 Identities = 78/366 (21%), Positives = 142/366 (38%), Gaps = 59/366 (16%) Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNT------- 203 T EKL Q + +T Q+++ +E + A E+L+ + + V T Sbjct: 171 TIEKLKQQNQEITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQH 230 Query: 204 -----EGLQKSLAELGGHLDQQVEEFRRRV------EPYGENFNKALVQQMEQLRQKLGP 252 EG + LA + ++V E R + + + +NK L ++ + LR +L Sbjct: 231 AARQKEGESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYK 290 Query: 253 HAGDVEGHLSFLEKDLRDKKFWYELEDTCPV-----GGLPPPVFSEQVMASMAAVLTWAL 307 + E DL+ +K ELE+ V G+ + Q M +L Sbjct: 291 NTQSNE--------DLKQEK--SELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQF 340 Query: 308 -ALLSAFSATQARKGFWDYFSQTSGDKGRV-EQIHQQKMAREP-AGSVRDD--LGTKEMM 362 + A A Q + + +Q G+V E + Q +M R+ A +++ + + + M Sbjct: 341 SSRCEAPDANQQLQQAMEERAQLEAHLGQVMESVRQLQMERDKYAENLKGESAMWRQRMQ 400 Query: 363 EASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEA----PRLPQDPVGMRRQ 418 + S TL++ E ++ + + L L A P P P + +Q Sbjct: 401 QMSEQV--------HTLREEKECSMSRVQELETSLAELRNQMAEPPPPEPPAGPSEVEQQ 452 Query: 419 LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 478 LQ E E ++ L+ + V N EGL + L + R+ EL+ + G Sbjct: 453 LQAEAEHLRKELEGLAGQLQAQVQDN-EGLSR--------LNREQEERLLELERAAELWG 503 Query: 479 EDTKAQ 484 E +A+ Sbjct: 504 EQAEAR 509
>gi|34222508|sp|Q15075|EEA1_HUMAN Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain containing protein 2) Length = 1411 Score = 35.0 bits (79), Expect = 0.087 Identities = 49/235 (20%), Positives = 109/235 (46%), Gaps = 28/235 (11%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIK---GREAEQLRRQLTPYAQR--------- 84 +L+N + V LQK ++ ++ T S +K + ++ L+ + + + Sbjct: 829 ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAIL 888 Query: 85 -MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS 143 +E+ +E LQ + E K ++ +++E+ K + + K++++ E+L ++ Sbjct: 889 DLEKTCKELKHQLQVQMENTLKEQK-ELKKSLEKEKEA----SHQLKLELNSMQEQLIQA 943 Query: 144 LAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNT 203 Q+ EK QL+G ++K+++E+ K +I A EL+ + E + T Sbjct: 944 QNTLKQN--EKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLT 1001 Query: 204 EGLQKSLAE------LGGHLDQQVEEFRR-RVEPYG-ENFNKALVQQMEQLRQKL 250 + Q+ AE L + ++ E F++ + + YG E+ A Q ++ + +KL Sbjct: 1002 QAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKL 1056
Score = 33.1 bits (74), Expect = 0.33 Identities = 40/227 (17%), Positives = 96/227 (42%), Gaps = 15/227 (6%) Query: 51 KSELTQQLK--KTGPSGIKGREAEQLRRQLTPYAQ-RMERVLRENADSLQASLRPHADEL 107 +++L Q+LK K ++ +QL+ + + E+ L+E + S +E+ Sbjct: 1073 QNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEI 1132 Query: 108 KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK 167 K + ++ + +L L + E +K +++ ++ L + Q K + L+ Q K Sbjct: 1133 KCRQEKEITKLNEELKSHKLE-SIKEITNLKDAKQLLIQQKLELQGKAD-SLKAAVEQEK 1190 Query: 168 KNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRR 227 +N + LK ++ EEL++ + ++ G++K ++ + + Sbjct: 1191 RNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKH--------EENEAKLTMQ 1242 Query: 228 VEPYGENFN--KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKK 272 + EN K Q ++ +L D+ G ++ LE +++ + Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQ 1289
Score = 29.3 bits (64), Expect = 4.8 Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 6/96 (6%) Query: 97 QASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE---ELRRSLAPYAQD--T 151 +A L+ H D + + +EL ++T D+ K+ E +L L Y + + Sbjct: 662 RADLQNHLDTAQNALQDKQQELN-KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLS 720 Query: 152 QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR 187 E+ +LEG +++ ++ E+KA + ++L+Q+ Sbjct: 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQ 756
>gi|17368936|sp|Q9H169|STN4_HUMAN Stathmin 4 (Stathmin-like protein B3) (RB3) Length = 189 Score = 34.7 bits (78), Expect = 0.11 Identities = 24/88 (27%), Positives = 43/88 (48%) Query: 184 LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQM 243 L +R P E+++ L E + AEL HL ++ E R ++ E N + Sbjct: 83 LPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAK 142 Query: 244 EQLRQKLGPHAGDVEGHLSFLEKDLRDK 271 E+L QK+ + + E HL+ + + L++K Sbjct: 143 EKLAQKMESNKENREAHLAAMLERLQEK 170
Score = 34.3 bits (77), Expect = 0.15 Identities = 23/99 (23%), Positives = 47/99 (47%), Gaps = 1/99 (1%) Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 EE++ ++ A+ E + + A L + + E +QK++ E + E+ +++E Sbjct: 92 EEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKMES 151 Query: 231 YGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLR 269 EN L +E+L++K HA +V + E+ R Sbjct: 152 NKENREAHLAAMLERLQEK-DKHAEEVRKNKELKEEASR 189
>gi|547749|sp|P13645|K1CJ_HUMAN Keratin, type I cytoskeletal 10 (Cytokeratin 10) (K10) (CK 10) Length = 593 Score = 34.7 bits (78), Expect = 0.11 Identities = 32/164 (19%), Positives = 72/164 (43%), Gaps = 21/164 (12%) Query: 74 LRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKI 133 L + L + E++ +N +A + EL +ID N+E+ ++ Y E Sbjct: 314 LTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQ----ISSYKSE----- 364 Query: 134 DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE 193 + ELRR++ + Q +L L ++ + E + R +++ +++ L E Sbjct: 365 ---ITELRRNVQALEIELQSQL-----ALKQSLEASLAETEGRYCVQLSQIQAQISALEE 416 Query: 194 DVRGNLRGNTEGLQ---KSLAELGGHLDQQVEEFRRRVEPYGEN 234 ++ +R TE + L ++ L+ +++ +R +E G + Sbjct: 417 QLQ-QIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSS 459
>gi|32469749|sp|Q8TBA6|GOA5_HUMAN Golgi autoantigen, golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein) Length = 731 Score = 34.3 bits (77), Expect = 0.15 Identities = 49/210 (23%), Positives = 96/210 (45%), Gaps = 23/210 (10%) Query: 381 DSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM---RRQLQEELEEVKARLQPYMAEA 437 D +L+N+ + LR +E L Q+ + ++ QEEL + +AR++ + A+ Sbjct: 218 DGKSHELSNLRLENQLLR----NEVQSLNQEMASLLQRSKETQEELNKARARVEKWNAD- 272 Query: 438 HELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQE-QLRVVGEDTKAQLLGGVDEAWALL 496 H GLR Q+ DL E VA + +L ++R+ D QLL EA L Sbjct: 273 HSKSDRMTRGLRAQVD----DLTEAVAAKDSQLAVLKVRLQEAD---QLLSTRTEALEAL 325 Query: 497 QGLQSRVVHHTGRFKELFHPYAESLVSGIG------RHVQELHRSVAPHAPASPARLSRC 550 Q +SR++ L + ++L + + QE ++ + A ++ Sbjct: 326 QSEKSRIMQDQSEGNSLQNQALQTLQERLHEADATLKREQESYKQMQSEFAARLNKVEME 385 Query: 551 VQVLSRKLTLKAKALHARIQQNLDQLREEL 580 Q L+ +TL A+ ++ ++ +D+L++++ Sbjct: 386 RQNLAEAITL-AERKYSDEKKRVDELQQQV 414
>gi|125081|sp|P19012|K1CO_HUMAN Keratin, type I cytoskeletal 15 (Cytokeratin 15) (K15) (CK 15) Length = 456 Score = 34.3 bits (77), Expect = 0.15 Identities = 43/191 (22%), Positives = 80/191 (41%), Gaps = 19/191 (9%) Query: 86 ERVLRENADSLQASLRPHA---DELKAKIDQNVEELKGRLTPYADEFKV-KIDQTVEELR 141 E++ +N + AS +E A ++ + + + TP + E + +T+EELR Sbjct: 105 EKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPASPECDYSQYFKTIEELR 164 Query: 142 RSLAPYAQDTQEKL----NHQLEGLTFQMK-KNAEELKARISASAEELRQRLAPLAEDVR 196 + D + N +L F++K +N L+ + A LR+ L L R Sbjct: 165 DKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTL-AR 223 Query: 197 GNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY---------GENFNKALVQQMEQLR 247 +L EGL + LA L + +++++EF ++ G + + L + EQ Sbjct: 224 TDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYE 283 Query: 248 QKLGPHAGDVE 258 + DVE Sbjct: 284 AMAEKNRRDVE 294
Score = 29.6 bits (65), Expect = 3.6 Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 32/152 (21%) Query: 74 LRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKI 133 L R L ++ E + +N ++A +EL ++ N E ++ T D Sbjct: 271 LTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITD------ 324 Query: 134 DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE 193 LRR++ Q+ + +L QL +KA + S E R A + Sbjct: 325 ------LRRTM----QELEIELQSQL------------SMKAGLENSLAETECRYATQLQ 362 Query: 194 DVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR 225 ++G + GL+ L+EL ++ Q +E++ Sbjct: 363 QIQGLI----GGLEAQLSELRCEMEAQNQEYK 390
>gi|12643547|sp|O15519|CFLA_HUMAN CASP8 and FADD-like apoptosis regulator precursor (Cellular FLICE-like inhibitory protein) (c-FLIP) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (MACH-related inducer of toxicity) (MRIT) (Caspase homolog) (CASH) (Inhibitor of FLICE) (I-FLICE) (FADD-like antiapoptotic molecule 1) (Flame-1) (Usurpin) Length = 480 Score = 34.3 bits (77), Expect = 0.15 Identities = 32/137 (23%), Positives = 67/137 (48%), Gaps = 5/137 (3%) Query: 83 QRMERVLRENADSLQASLRP-HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELR 141 +++ V + D L+ L+ H +LK KI + + ++G T Y + + I +++++ Sbjct: 139 EKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPS 198 Query: 142 RSLAPY-AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL--APLAEDVRGN 198 + + + +++L QL +KK+ +E +A + S E R ++ PL + + Sbjct: 199 NNFRLHNGRSKEQRLKEQLGAQQEPVKKSIQESEAFLPQSIPEERYKMKSKPLGICLIID 258 Query: 199 LRGN-TEGLQKSLAELG 214 GN TE L+ + LG Sbjct: 259 CIGNETELLRDTFTSLG 275
>gi|400793|sp|Q00722|PIB2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (Phosphoinositide phospholipase C) (PLC-beta-2) (Phospholipase C-beta-2) Length = 1181 Score = 34.3 bits (77), Expect = 0.15 Identities = 45/220 (20%), Positives = 83/220 (37%), Gaps = 15/220 (6%) Query: 57 QLKKTGPSGIKGREAEQLRRQLTPYAQRMERVL-RENADSLQASLRPHADELKAKIDQNV 115 QL + GP G+ G A +L R +R L RE + P +D V Sbjct: 926 QLAELGPPGVGGVGACKLG---PGKGSRKKRSLPREESAGAAPGEGPEG------VDGRV 976 Query: 116 EELKGRLT-----PYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA 170 ELK RL ++++ + + + + ++ + +EK +L+ L + + Sbjct: 977 RELKDRLELELLRQGEEQYECVLKRKEQHVAEQISKMMELAREKQAAELKALKETSENDT 1036 Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 +E+K ++ E Q + + D R E + E+ + Q E R E Sbjct: 1037 KEMKKKLETKRLERIQGMTKVTTDKMAQERLKREINNSHIQEVVQVIKQMTENLERHQEK 1096 Query: 231 YGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRD 270 E L Q E +Q + E + LE ++++ Sbjct: 1097 LEEKQAACLEQIREMEKQFQKEALAEYEARMKGLEAEVKE 1136
>gi|128142|sp|P07196|NFL_HUMAN Neurofilament triplet L protein (68 kDa neurofilament protein) (Neurofilament light polypeptide) (NF-L) Length = 544 Score = 34.3 bits (77), Expect = 0.15 Identities = 51/222 (22%), Positives = 94/222 (42%), Gaps = 33/222 (14%) Query: 66 IKGREAEQLRRQLTPYAQRMERVL--RENADSLQASLRPHADEL---KAKIDQNVEELKG 120 ++G E L L R E + RE+A+ R ADE +A++++ ++ L Sbjct: 160 LRGEREEGLEETLRNLQARYEEEVLSREDAEGRLMERRKGADEAALARAELEKRIDSLMD 219 Query: 121 RLTPYADEFKVKI-DQTVEELRRSLAPYAQDTQEK--LNHQLEGLTFQMKKNAEELKARI 177 ++ F K+ ++ + EL+ + YAQ + E L ++ E+L A+ Sbjct: 220 EIS-----FLKKVHEEEIAELQAQIQ-YAQISVEMDVTKPDLSAALKDIRAQYEKLAAKN 273 Query: 178 SASAEE-LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYG---- 232 +AEE + R L E N T+ ++ + E V E RR ++ Sbjct: 274 MQNAEEWFKSRFTVLTESAAKN----TDAVRAAKDE--------VSESRRLLKAKTLEIE 321 Query: 233 --ENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKK 272 N+AL +Q+++L K ++ ++ LE +LR K Sbjct: 322 ACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTK 363
>gi|2495703|sp|Q14139|UB4A_HUMAN Ubiquitin conjugation factor E4 A Length = 1073 Score = 34.3 bits (77), Expect = 0.15 Identities = 29/112 (25%), Positives = 43/112 (38%), Gaps = 9/112 (8%) Query: 574 DQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEV 633 D LRE+ R +PQML + ++ + + AI E + Sbjct: 562 DNLREQFERLMTIYLSTKTAMTEPQMLQNCLNLQVS-------MAVLLVQLAIGNEGSQP 614 Query: 634 QQQLAPPPPGHS--AFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGH 683 + P P G+S A+ PEF + G L L+ DD+ E SL H Sbjct: 615 IELTFPLPDGYSSLAYVPEFFADNLGDFLIFLRRFADDILETSADSLEHVLH 666
>gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin) Length = 2418 Score = 34.3 bits (77), Expect = 0.15 Identities = 101/495 (20%), Positives = 182/495 (36%), Gaps = 69/495 (13%) Query: 104 ADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYA---------QDTQEK 154 ADE AK EE+ RL D +K Q ++E R L YA ++ +E Sbjct: 1462 ADEHYAK-----EEIATRLQRVLDRWKALKAQLIDE-RTKLGDYANLKQFYRDLEELEEW 1515 Query: 155 LNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLR-----------GNT 203 ++ L + K+A ++ + + + +E V G + GN Sbjct: 1516 ISEMLPTACDESYKDATNIQRKY-LKHQTFAHEVDGRSEQVHGVINLGNSLIERSCDGNE 1574 Query: 204 EGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF 263 E +++ L +L H D +E R G+ N+A Q Q+ D E LS Sbjct: 1575 EAMKEQLEQLKEHWDHLLE----RTNDKGKKLNEASRQ------QRFNTSIRDFEFWLSE 1624 Query: 264 LEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFW 323 E L K + D G L + Q++ AL L+ + G + Sbjct: 1625 AETLLAMKD---QARDLASAGNL---LKKHQLLEREMLAREDALKDLNTLAEDLLSSGTF 1678 Query: 324 DYFSQTSGDKGRVEQ--IHQQKMAREPAGSVRDDLGTKE-MMEASSLTAWISVPFSRTLK 380 + Q K V + ++ Q++A +++ + + +WI R Sbjct: 1679 N-VDQIVKKKDNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSS 1737 Query: 381 DSLEQDLNNMNKFLEKLRPLSGSEAPRLP--QDPVGMRRQLQEEL----EEVKARLQPYM 434 +DL + L+K + L G P Q+ + M +L+++ EE++ RL ++ Sbjct: 1738 QDYGRDLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEEIQLRLAQFV 1797 Query: 435 AEAHELVGWNLEGLRQQLKPYTMDLMEQVALR--VQELQEQLRVVGEDTKAQLLGGVDEA 492 W E L++ K + L E + +Q +E+ + E + G + Sbjct: 1798 EH------W--EKLKELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDT 1849 Query: 493 WALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQ 552 A Q L + H H E+ V + +++ V H + +S ++ Sbjct: 1850 LAATQSLLMK--HEALENDFAVH---ETRVQNVCAQGEDILNKVL-HEESQNKEISSKIE 1903 Query: 553 VLSRKLTLKAKALHA 567 L+ K AKA+ A Sbjct: 1904 ALNEKTPSLAKAIAA 1918
>gi|51701377|sp|O15083|ERC2_HUMAN ERC protein 2 Length = 957 Score = 33.9 bits (76), Expect = 0.19 Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 27/204 (13%) Query: 52 SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI 111 S+L QLKK E R +A +++++ +E + R + +A++ Sbjct: 679 SKLEAQLKKA-------HNIEDDSRMNPEFADQIKQLDKE-----ASYYRDECGKAQAEV 726 Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA- 170 D+ +E LK + K D+ + EL + +D +K+ + + KKNA Sbjct: 727 DRLLEILKE-----VENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQ 781 Query: 171 --EELKARISASAEELR----QRLAPLAEDVRGNL---RGNTEGLQKSLAELGGHLDQQV 221 EE++ R + A+ + + L E R L + Q+SLAE HL Sbjct: 782 LLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLR 841 Query: 222 EEFRRRVEPYGENFNKALVQQMEQ 245 E R+++E E +AL+ + + Sbjct: 842 IERRKQLEEILEMKQEALLAAISE 865
Score = 33.5 bits (75), Expect = 0.25 Identities = 50/233 (21%), Positives = 97/233 (41%), Gaps = 13/233 (5%) Query: 43 KEAVEHLQKSEL-TQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLR 101 K+ +E LQ L ++ L+ + EAE L + E+ + L + Sbjct: 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQ 365 Query: 102 PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEG 161 + K K Q V E+K + ++ ++ L+ + +D +E++ Q+E Sbjct: 366 LQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIK-QIEV 424 Query: 162 LTFQ---MKKNAEELKARISASAEEL---RQRLAPLAEDVRGNLRGNTEGLQKSLA---E 212 MK ++LK +S EL + +L L+ + + + E L++SL + Sbjct: 425 YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQ-NSDCKQHIEVLKESLTAKEQ 483 Query: 213 LGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLE 265 L +V+ R R+E E+F +Q++ L ++ G AG++ LE Sbjct: 484 RAAILQTEVDALRLRLEEK-ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLE 535
Score = 29.6 bits (65), Expect = 3.6 Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 18/169 (10%) Query: 106 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ 165 E + K N+E+ R+ P EF +I Q +E A Y +D K +++ L Sbjct: 682 EAQLKKAHNIED-DSRMNP---EFADQIKQLDKE-----ASYYRDECGKAQAEVDRLLEI 732 Query: 166 MKK--NAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE 223 +K+ N + K + A E L R NL+ N + +K A+L +EE Sbjct: 733 LKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQL-------LEE 785 Query: 224 FRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKK 272 RRR + +N ++++ +K + L+ ++ L +K+ Sbjct: 786 VRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKE 834
>gi|33860140|sp|Q13625|ASP2_HUMAN Apoptosis stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (53BP2) (Bcl2-binding protein) (Bbp) Length = 1128 Score = 33.9 bits (76), Expect = 0.19 Identities = 51/200 (25%), Positives = 83/200 (41%), Gaps = 17/200 (8%) Query: 50 QKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKA 109 Q+ E QQL T +K + + R+Q Q + L+E A++ +A L+ LK Sbjct: 140 QQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLK-KVRALKG 198 Query: 110 KIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL---TFQM 166 ++Q G+L ++ Q EL A E+L QLE L Sbjct: 199 HVEQK-RLSNGKLVEEIEQMNNLFQQKQREL-----VLAVSKVEELTRQLEMLKNGRIDS 252 Query: 167 KKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRR 226 + + A + +EL+ R L ++ L+ E L K +E+ +D++V E R Sbjct: 253 HHDNQSAVAELDRLYKELQLR-NKLNQEQNAKLQQQRECLNKRNSEV-AVMDKRVNELRD 310 Query: 227 RVEPYGENFNKALVQQMEQL 246 R+ KA +QQ E L Sbjct: 311 RLWK-----KKAALQQKENL 325
>gi|2497600|sp|Q13751|LAMB3_HUMAN Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain) Length = 1172 Score = 33.5 bits (75), Expect = 0.25 Identities = 42/171 (24%), Positives = 74/171 (43%), Gaps = 23/171 (13%) Query: 68 GREAEQLR--RQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGR--LT 123 G+ AEQLR ++M R E+A +Q+S + ++ A Q E+++ L Sbjct: 833 GQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLI 892 Query: 124 PYADEFKVKIDQ---TVEELRRSLAPYAQDTQ-----EKLNH------QLEGLTFQMKKN 169 +F D T++E+ ++ T +K+N +L + + + Sbjct: 893 QQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT 952 Query: 170 AEELKA--RISASAEELRQRLAPL---AEDVRGNLRGNTEGLQKSLAELGG 215 +++ R+ A AEE R R + EDV GNLR T LQ++ + G Sbjct: 953 KQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQG 1003
>gi|1730573|sp|Q01970|PIB3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (Phosphoinositide phospholipase C) (PLC-beta-3) (Phospholipase C-beta-3) Length = 1234 Score = 33.5 bits (75), Expect = 0.25 Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 10/121 (8%) Query: 377 RTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM------RRQLQEELEEVKARL 430 + LK+ E++ + K L++ R S SEA + RR + E + ++ RL Sbjct: 1081 KRLKEMNEREKKELQKILDRKRHNSISEAKMRDKHKKEAELTEINRRHITESVNSIR-RL 1139 Query: 431 QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVD 490 + + H+ + + + QQL L+ Q+A QE QEQ + ++ + LLG + Sbjct: 1140 EEAQKQRHDRLVAGQQQVLQQLAEEEPKLLAQLA---QECQEQRARLPQEIRRSLLGEMP 1196 Query: 491 E 491 E Sbjct: 1197 E 1197
>gi|6685537|sp|Q14152|IF3A_HUMAN Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) Length = 1382 Score = 33.5 bits (75), Expect = 0.25 Identities = 35/154 (22%), Positives = 72/154 (46%), Gaps = 16/154 (10%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSL 96 Q KE +E L ++L++ K R+AE+ R + + ER+L+E+ Sbjct: 573 QTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIK 632 Query: 97 QASLRPHADEL-------KAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ 149 + ++R +++ KA D ++E+L+ L P D K + +E+ ++ L + Sbjct: 633 KKTVRERLEQIKKTELGAKAFKDIDIEDLE-ELDP--DFIMAKQVEQLEKEKKELQERLK 689 Query: 150 DTQEKLNHQLEGLTFQMKKNAEELKARISASAEE 183 + ++K+++ F+ K EE+ SA E+ Sbjct: 690 NQEKKIDY------FERAKRLEEIPLIKSAYEEQ 717
>gi|13431563|sp|O75146|HIPR_HUMAN Huntingtin interacting protein 1 related (Hip1-related) (Hip 12) Length = 1068 Score = 33.5 bits (75), Expect = 0.25 Identities = 66/249 (26%), Positives = 101/249 (40%), Gaps = 40/249 (16%) Query: 419 LQEELEEVKARLQPYMAEAHELVGWNLEG-LRQQLKPYTMDLMEQVALRVQELQEQLRVV 477 L+ ELE++K Q Y+A+ V LEG L +Q K L++ LR EL + Sbjct: 366 LRSELEKIKLEAQRYIAQLKSQVN-ALEGELEEQRKQKQKALVDNEQLR-HELAQLRAAQ 423 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSG------------- 524 E ++Q G +EA ++R + EL H +AE L Sbjct: 424 LEGERSQ--GLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNADTAKQLTVTQQS 481 Query: 525 ---IGRHVQELHRSVAPHAPASPARL---SRCVQVLSRKLTLKAKALHARIQQNL---DQ 575 + R ++L V S +L S ++ L R+L KA L AR Q+ L +Q Sbjct: 482 QEEVARVKEQLAFQVEQVKRESELKLEEKSDQLEKLKRELEAKAGEL-ARAQEALSHTEQ 540 Query: 576 LREELSRAFXXXXXXXXXXPDPQMLSEEVRQR------LQAFRQDTYLQIAAFTRAIDQE 629 + ELS + LS VRQR Q+ ++T ++ + QE Sbjct: 541 SKSELSSRLDTLSA------EKDALSGAVRQREADLLAAQSLVRETEAALSREQQRSSQE 594 Query: 630 TEEVQQQLA 638 E+Q +LA Sbjct: 595 QGELQGRLA 603
Score = 31.2 bits (69), Expect = 1.3 Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 20/188 (10%) Query: 34 YFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENA 93 Y +QL K V L+ EL +Q K+ + + + EQLR +L R ++ E + Sbjct: 380 YIAQL----KSQVNALE-GELEEQRKQKQKALV---DNEQLRHELAQL--RAAQLEGERS 429 Query: 94 DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE 153 L+ A +A+ ++ E+ + +A+ + D T ++L Q +QE Sbjct: 430 QGLREEAERKASATEARYNKLKEKHSELVHVHAELLRKNAD-TAKQLT-----VTQQSQE 483 Query: 154 KLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGL---QKSL 210 ++ E L FQ+++ E + ++ +++L ++L E G L E L ++S Sbjct: 484 EVARVKEQLAFQVEQVKRESELKLEEKSDQL-EKLKRELEAKAGELARAQEALSHTEQSK 542 Query: 211 AELGGHLD 218 +EL LD Sbjct: 543 SELSSRLD 550
Score = 29.6 bits (65), Expect = 3.6 Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 20/135 (14%) Query: 134 DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE 193 D +E L+R + E L +LE + + ++ +LK++++A EL ++ + Sbjct: 353 DLQIESLKREV--------EMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQK 404 Query: 194 DVRGNLRGNTEGLQKSLAELGGHLDQQV-EEFRRRVEPYGENFNKALVQQMEQLRQKLGP 252 + N + E Q A+L G Q + EE R+ +NK L++K Sbjct: 405 ALVDNEQLRHELAQLRAAQLEGERSQGLREEAERKASATEARYNK--------LKEK--- 453 Query: 253 HAGDVEGHLSFLEKD 267 H+ V H L K+ Sbjct: 454 HSELVHVHAELLRKN 468
>gi|3024609|sp|Q15431|SYCP1_HUMAN Synaptonemal complex protein 1 (SCP-1 protein) Length = 976 Score = 33.5 bits (75), Expect = 0.25 Identities = 46/257 (17%), Positives = 106/257 (41%), Gaps = 20/257 (7%) Query: 29 TVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERV 88 T + + ++LS KE + + S++T +LK ++ E+ + Q E Sbjct: 514 TELTSHCNKLSLENKELTQ--ETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ 571 Query: 89 LRENADSLQASLRPHADELKAKIDQNVEELKG--RLTPYADEFKVKIDQTVEELRRSLAP 146 LR + ++ L+ DE+K K+D++ E + +++ ++ Q + L++ Sbjct: 572 LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTA 631 Query: 147 YAQDTQ------EKLNHQLEG-------LTFQMKKNAEELKARISASAEELRQRLAPLAE 193 ++ KL +LE +T +K E+ K EE+ ++ +A+ Sbjct: 632 ESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEV-EKAKVIAD 690 Query: 194 DVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN--KALVQQMEQLRQKLG 251 + + + Q +AE+ +++ ++ + +E K+ Q+ LR L Sbjct: 691 EAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLE 750 Query: 252 PHAGDVEGHLSFLEKDL 268 +++ L ++K L Sbjct: 751 IELSNLKAELLSVKKQL 767
>gi|50403793|sp|Q96L93|SNXN_HUMAN Kinesin-like motor protein C20orf23 (Sorting nexin 23) Length = 1317 Score = 33.5 bits (75), Expect = 0.25 Identities = 58/237 (24%), Positives = 108/237 (45%), Gaps = 38/237 (16%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQ-LRRQLTPYAQRMERVLRENADSLQASLR 101 K +E +Q+ E+ Q K+T ++ R+ E+ L+R+ +++ +L E + LR Sbjct: 627 KAELERMQQ-EVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLR 685 Query: 102 PHAD-ELKAKIDQN-----VEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKL 155 + EL+ K + V+E RL + K + Q +EL Q++ Sbjct: 686 EQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQEL--------DQLQKEK 737 Query: 156 NHQLEGLTFQMKKNAEELKARISASA---EELRQRLAPLAEDVRGNL------RGNTEGL 206 + Q L + K+ E+ K ++ A E+LR++ + RG + + + EG+ Sbjct: 738 DEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGI 797 Query: 207 QKSL-----AELGGHLD-QQVE-------EFRRRVEPYGENFNKALVQQMEQLRQKL 250 ++SL A GG D +++E EF+RR N K LVQQ + L++++ Sbjct: 798 RESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEV 854
Score = 28.5 bits (62), Expect = 8.1 Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 10/90 (11%) Query: 418 QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVV 477 Q+++E+EE + +L Y A A++L Q+L+ T + +A + ++++++ + + Sbjct: 944 QVEKEMEEKEEQLAQYQANANQL---------QKLQA-TFEFTANIARQEEKVRKKEKEI 993 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHT 507 E + Q ++ A A L+ S + H+ Sbjct: 994 LESREKQQREALERALARLERRHSALQRHS 1023
>gi|41688581|sp|Q86VS8|HOK3_HUMAN Hook homolog 3 (hHK3) Length = 718 Score = 33.5 bits (75), Expect = 0.25 Identities = 46/218 (21%), Positives = 98/218 (44%), Gaps = 28/218 (12%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRP 102 +E+V+H+ + + + + K P L RQL + + L + Q R Sbjct: 143 EESVQHVVMTAIQELMSKESPVSAGNDAYVDLDRQLKKTTEELNEALSAKEEIAQ---RC 199 Query: 103 HADELKAKIDQNVEELKGRLTPYADEFKVKIDQ-----TVEELRRSLAPYAQDTQEKLNH 157 H ++D V L+ + E +V +++ ++E+ Q +L Sbjct: 200 H------ELDMQVAALQEEKSSLLAENQVLMERLNQSDSIEDPNSPAGRRHLQLQTQL-E 252 Query: 158 QLEGLTFQMKKNAEELKAR---ISASAEELRQR---LAPLAEDVRGNLRGNTEGLQKSLA 211 QL+ TF+++ ++ + R + ELRQ+ L LA++ + +L+ + L+ S + Sbjct: 253 QLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTLADEAQ-SLKDEIDVLRHS-S 310 Query: 212 ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 + L+ QVE +++++E G+ L +Q++ L +K Sbjct: 311 DKVSKLEGQVESYKKKLEDLGD-----LRRQVKLLEEK 343
>gi|47117845|sp|P32856|EPMO_HUMAN Epimorphin (Syntaxin 2) Length = 288 Score = 33.1 bits (74), Expect = 0.33 Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 2/57 (3%) Query: 132 KIDQTVEELRR--SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQ 186 KI Q VEE+++ S+ A + + K+ +LE L ++KK A +++A++ A + Q Sbjct: 45 KITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ 101
Score = 29.3 bits (64), Expect = 4.8 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 11/84 (13%) Query: 127 DEFKVKIDQTVEELRRSLAPYAQDTQE-KLNHQL-------EGLTFQMKKNAEELKARIS 178 D F VEE+R S+ Q +E K NH + EG ++K+ E+L I Sbjct: 26 DHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEG---KIKEELEDLNKEIK 82 Query: 179 ASAEELRQRLAPLAEDVRGNLRGN 202 +A ++R +L + + + GN Sbjct: 83 KTANKIRAKLKAIEQSFDQDESGN 106
>gi|51704330|sp|Q93045|STN2_HUMAN Stathmin 2 (SCG10 protein) (Superior cervical ganglion-10 protein) Length = 179 Score = 33.1 bits (74), Expect = 0.33 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 19/147 (12%) Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA-PYAQDTQEKLNHQLEGLTFQMKKNA 170 D V+++ R + A E +K + E R+LA P +D + Sbjct: 39 DMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDL-----------------SL 81 Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 EE++ ++ A+ E + + A + + + E LQK+L E E+ ++E Sbjct: 82 EEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQ 141 Query: 231 YGENFNKALVQQMEQLRQKLGPHAGDV 257 EN L +E+L++K HA +V Sbjct: 142 IKENREANLAAIIERLQEK-ERHAAEV 167
>gi|56405385|sp|Q9HCM9|TM39_HUMAN Tripartite motif protein 39 (RING finger protein 23) (Testis-abundant finger protein) Length = 518 Score = 33.1 bits (74), Expect = 0.33 Identities = 43/161 (26%), Positives = 65/161 (40%), Gaps = 32/161 (19%) Query: 128 EFKVKIDQTVEELRRSLAPYAQ--DTQEK----LNHQLEGLTFQMKKNAEELKARISASA 181 E+K K+ + +E L + L + ++EK L +E Q+ + EEL R+ Sbjct: 149 EYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQ 208 Query: 182 EELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQ 241 + L RL +D+ LR N L +L HL +VE K L Sbjct: 209 QVLLSRLEEEEQDILQRLRENAAHLGDKRRDL-AHLAAEVE-------------GKCLQS 254 Query: 242 QMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCP 282 E L+ DV+ S LEK++ +KF L CP Sbjct: 255 GFEMLK--------DVK---STLEKNI-PRKFGGSLSTICP 283
Score = 30.0 bits (66), Expect = 2.8 Identities = 27/115 (23%), Positives = 51/115 (44%), Gaps = 10/115 (8%) Query: 85 MERVLRENADSLQASLRPHADELK--AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 ++ +E + LQ L P +L+ + + E+ G L + + +I + EEL R Sbjct: 143 LDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRG 197 L Q +L + + + ++++NA L + R+ LA LA +V G Sbjct: 203 RLDEEQQVLLSRLEEEEQDILQRLRENAAHL--------GDKRRDLAHLAAEVEG 249
>gi|46397807|sp|O76014|K1M7_HUMAN Keratin, type I cuticular HA7 (Hair keratin, type I HA7) Length = 449 Score = 33.1 bits (74), Expect = 0.33 Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 31/176 (17%) Query: 90 RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSL---- 144 + + ++ Q SL+ LK+ +Q V+ L+ +L ++F++++D + +L R L Sbjct: 221 KADLEAQQESLKEEQLSLKSNHEQEVKILRSQL---GEKFRIELDIEPTIDLNRVLGEMR 277 Query: 145 APYA-------QDTQEKLNHQLEGLTFQMKKNAEELKA--------RISASAEELRQRLA 189 A Y QD ++ Q EG++ Q +EEL+ R + +A E+ ++ Sbjct: 278 AQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQ 337 Query: 190 PLAEDVRGNL------RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL 239 +D N R TE Q + L +L++Q+ E R +E + + L Sbjct: 338 HTLKDCLQNSLCEAEDRYGTELAQ--MQSLISNLEEQLSEIRADLERQNQEYQVLL 391
Score = 30.8 bits (68), Expect = 1.6 Identities = 42/221 (19%), Positives = 97/221 (43%), Gaps = 22/221 (9%) Query: 62 GPSGIKGREAEQLR---RQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEEL 118 G + + G E E ++ +L Y +++ ++ +ENA EL+ + + + Sbjct: 96 GKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENA------------ELETTLLERSKCH 143 Query: 119 KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 178 + + P + I++ +++ S A A+ + N +L F++K +E ++ Sbjct: 144 ESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLV 203 Query: 179 ASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKA 238 + + Q+L A + +L E L++ L + +Q+V+ R ++ GE F Sbjct: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQL---GEKFRIE 260 Query: 239 L-VQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELE 278 L ++ L + LG E + +E + +D + W++ + Sbjct: 261 LDIEPTIDLNRVLGEMRAQYE---AMVETNHQDVEQWFQAQ 298
>gi|41688592|sp|Q96ED9|HOK2_HUMAN Hook homolog 2 (h-hook2) (hHK2) Length = 719 Score = 33.1 bits (74), Expect = 0.33 Identities = 53/225 (23%), Positives = 92/225 (40%), Gaps = 24/225 (10%) Query: 69 REAEQLRRQLTPYAQRMERVLRE--NADSLQASLRPHADELKAKIDQNVE--------EL 118 R+ ++L+ QL A + E+ L E N + S+ + L A+ D E +L Sbjct: 367 RQVQELQGQLQEEAMKAEKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCAQL 426 Query: 119 KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNA-----EEL 173 + R AD V+ L + P A+ + L QLE ++ A EEL Sbjct: 427 QPRGLTQADPSLDPTSTPVDNLAAEILP-AELRETLLRLQLENKRLCRQEAADRERQEEL 485 Query: 174 KARISASAEELRQRLAP---LAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE-EFRRRVE 229 + + A R L L + LR E LQK+L E GG + + +R++E Sbjct: 486 QRHLE-DANRARHGLETQHRLNQQQLSELRAQVEDLQKALQEQGGKTEDAISILLKRKLE 544 Query: 230 PYGENFNKA---LVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK 271 + + ++A L ++ E + + P + L+ +L+ K Sbjct: 545 EHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNLQKK 589
>gi|41702296|sp|Q8NI27|THO2_HUMAN THO complex subunit 2 (Tho2) Length = 1478 Score = 33.1 bits (74), Expect = 0.33 Identities = 37/168 (22%), Positives = 72/168 (42%), Gaps = 28/168 (16%) Query: 67 KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYA 126 KG+E E+ +++ TP RVL ++ RP+ DE E K R TP + Sbjct: 1158 KGKEKEKEKKEKTPATTPEARVLGKDGKEKPKEERPNKDE-------KARETKER-TPKS 1209 Query: 127 DEFKVKI---DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEE 183 D+ K K ++ +E ++ P A+ + ++ E+ +R A+E Sbjct: 1210 DKEKEKFKKEEKAKDEKFKTTVPNAESKSTQ------------EREREKEPSRERDIAKE 1257 Query: 184 LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY 231 ++ + E+V+G + G KS + + E+ RR+++ + Sbjct: 1258 MKSK-----ENVKGGEKTPVSGSLKSPVPRSDIPEPEREQKRRKIDTH 1300
>gi|37537873|sp|Q9Y6C2|EMIL1_HUMAN EMILIN 1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1) Length = 1016 Score = 33.1 bits (74), Expect = 0.33 Identities = 49/202 (24%), Positives = 81/202 (40%), Gaps = 34/202 (16%) Query: 44 EAVEHLQKS--ELTQQLK--KTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQAS 99 E V+ L++ LT++L+ + G+ GR AE ++R + E A+ Sbjct: 176 EKVQQLEEQVQSLTKELQGLRGVLQGLSGRLAEDVQRAV-------ETAFNGRQQPADAA 228 Query: 100 LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQ---------------------TVE 138 RP E +I ++ L R++ + E + E Sbjct: 229 ARPGVHETLNEIQHQLQLLDTRVSTHDQELGHLNNHHGGSSSSGGSRAPAPASAPPGPSE 288 Query: 139 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAEDVR 196 EL R L Q++ L+G Q +++ E L+A ++ AS EE ++ LA LA R Sbjct: 289 ELLRQLEQRLQESCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVEERQRHLAGLAVGRR 348 Query: 197 GNLRGNTEGLQKSLAELGGHLD 218 + L + LAEL LD Sbjct: 349 PPQECCSPELGRRLAELERRLD 370
>gi|38605067|sp|Q9NSB8|HOM2_HUMAN Homer protein homolog 2 (Homer-2) Length = 354 Score = 32.7 bits (73), Expect = 0.43 Identities = 39/179 (21%), Positives = 73/179 (40%), Gaps = 17/179 (9%) Query: 23 SADQVATVMWDYFSQLSNNAKEAVEHLQK-----SELTQQLKKTGPSGIKGREAEQLRRQ 77 S++Q T + F ++ AK A + Q+ S +Q+ + PS + + Sbjct: 91 SSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIETSSNHSQESGRETPSSTQASSVNGTDDE 150 Query: 78 LTPYAQRMERVLRENADSLQASLRPHADELKA-KID-QNVEELKGRLTPYADEFKVKIDQ 135 +A L+ D L+ +L A +K +I+ Q + E RLT E ++Q Sbjct: 151 KASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRESNARLTTALQESAASVEQ 210 Query: 136 TVEELR---------RSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR 185 + R+ ++ ++N + E T Q+K+ EEL+A + EL+ Sbjct: 211 WKRQFSICRDENDRLRNKIDELEEQCSEINREKEKNT-QLKRRIEELEAELREKETELK 268
>gi|32699595|sp|Q96CN9|GCC1_HUMAN GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1) Length = 775 Score = 32.7 bits (73), Expect = 0.43 Identities = 77/326 (23%), Positives = 124/326 (38%), Gaps = 67/326 (20%) Query: 161 GLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRG--NLRGNTEGLQKSLAELGGHLD 218 G+ F + ++L I ++L Q A L + VR +L E L+ S+ L + Sbjct: 5 GMNFGGGPSKKDLLETIETQKKQLLQYQARLKDVVRAYKSLLKEKEALEASIKVLS--VS 62 Query: 219 QQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEK--DLRDKKFWYE 276 + + V+ G F + + + H+ D G + L+ L K + Sbjct: 63 HEADVGLAGVQLPGLTFP-------DSVDDRCSTHSEDSTGTATSLDTAASLTSTKGEFG 115 Query: 277 LEDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRV 336 +ED P G PPP E +W+ + +S+ S G G V Sbjct: 116 VEDDRPARGPPPPKSEEA---------SWSESGVSSSSGDGPFAG------------GEV 154 Query: 337 EQ-IHQQKMAREP-AGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFL 394 ++ +HQ K S+ K MEAS L K ++QDL + + Sbjct: 155 DKRLHQLKTQLATLTSSLATVTQEKSRMEASYLAD----------KKKMKQDLEDASNKA 204 Query: 395 EKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARL------QPYMAEAHELVGWNLEGL 448 E+ E RL G + LQE++ E KARL + H L+ L+ L Sbjct: 205 EE-------ERARLE----GELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKL 253 Query: 449 RQQLKPYTMDLMEQVALRVQELQEQL 474 Q+ + DL LR++E +E L Sbjct: 254 LQEERTQRQDL----ELRLEETREAL 275
Score = 30.0 bits (66), Expect = 2.8 Identities = 33/139 (23%), Positives = 65/139 (46%), Gaps = 17/139 (12%) Query: 146 PYAQDTQEKLNHQLEG----LTFQMKKNAEELKARISAS----AEELRQRLAPL---AED 194 P+A +K HQL+ LT + +E K+R+ AS ++++Q L AE+ Sbjct: 148 PFAGGEVDKRLHQLKTQLATLTSSLATVTQE-KSRMEASYLADKKKMKQDLEDASNKAEE 206 Query: 195 VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA 254 R L G +GLQ+ +AE L Q + + ++ + +++++++L Q+ Sbjct: 207 ERARLEGELKGLQEQIAETKARLITQQHDRAQE-----QSDHALMLRELQKLLQEERTQR 261 Query: 255 GDVEGHLSFLEKDLRDKKF 273 D+E L + L + + Sbjct: 262 QDLELRLEETREALAGRAY 280
>gi|13123953|sp|Q9Y6Q5|AP1M2_HUMAN Adaptor-related protein complex 1, mu 2 subunit (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B) Length = 423 Score = 32.7 bits (73), Expect = 0.43 Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 9/97 (9%) Query: 418 QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQL--R 475 Q +LE K+R+ P + A V W EG++ + +D++E V L V L Sbjct: 137 QQSNKLETGKSRVPPTVTNA---VSWRSEGIKYKKNEVFIDVIESVNLLVNANGSVLLSE 193 Query: 476 VVGEDTKAQLLGGVDEAWALLQGLQSRVVHH-TGRFK 511 +VG L G+ E L GL RV+ TGR K Sbjct: 194 IVGTIKLKVFLSGMPE---LRLGLNDRVLFELTGRSK 227
>gi|55976724|sp|Q7Z7L9|ZSCA2_HUMAN Zinc finger and SCAN domain containing protein 2 (Zinc finger protein 29 homolog) (Zfp-29) Length = 613 Score = 32.7 bits (73), Expect = 0.43 Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 3/71 (4%) Query: 62 GPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGR 121 GP G GR E RR L P E++L +QA L+ H E + VE+L Sbjct: 72 GPQGALGRLRELCRRWLRPEVHTKEQMLTMLPKEIQAWLQEHRPESSEEAAALVEDLTQT 131 Query: 122 LTPYADEFKVK 132 L D F+++ Sbjct: 132 L---QDNFEIQ 139
>gi|134798|sp|P11277|SPTB1_HUMAN Spectrin beta chain, erythrocyte (Beta-I spectrin) Length = 2137 Score = 32.7 bits (73), Expect = 0.43 Identities = 43/183 (23%), Positives = 69/183 (37%), Gaps = 36/183 (19%) Query: 113 QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMK-KNAE 171 +N++ +L +F + Q +E L R T+EK H + ++ + Sbjct: 1330 ENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHA 1389 Query: 172 ELKARISASAEELR------------QRLAPLAE-----DVRGNLRGNTEGLQKSLAELG 214 +L ISA ++LR + LA L +VR G S+ E G Sbjct: 1390 DLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEG 1449 Query: 215 GHLDQQVEE-FRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKF 273 G D +E+ F +EP G +Q+E R KL + +DL D+ Sbjct: 1450 GDADLSIEKRFLDLLEPLGRR-----KKQLESSRAKLQ------------ISRDLEDETL 1492 Query: 274 WYE 276 W E Sbjct: 1493 WVE 1495
Score = 31.2 bits (69), Expect = 1.3 Identities = 49/262 (18%), Positives = 104/262 (39%), Gaps = 56/262 (21%) Query: 384 EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQ---------PYM 434 ++ ++N+N F+E+L SEA + + G+ + LE + R+Q Y Sbjct: 1744 QERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYF 1803 Query: 435 AEAHELVGWNLEGLRQQLKPYTMDL----------------MEQVALRVQELQE---QLR 475 E++G E R+ + +D + + ++VQ+ Q+ +L+ Sbjct: 1804 YTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQ 1863 Query: 476 VVGEDTKAQLLGG----VDEAWALL----QGLQSRVVHHTGRFKELFHPYAESLVSGIGR 527 KA+ + V AW L G ++++V +F+ F A L+S + Sbjct: 1864 TAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFR--FFSMARDLLSWMES 1921 Query: 528 HVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXX 587 ++++ P +S L + Q ++ ++ ++K A ++ L+ + Sbjct: 1922 IIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQ-------- 1973 Query: 588 XXXXXXXPDPQMLSEEVRQRLQ 609 SEE+R++LQ Sbjct: 1974 ----------HQASEEIREKLQ 1985
Score = 29.3 bits (64), Expect = 4.8 Identities = 65/284 (22%), Positives = 112/284 (39%), Gaps = 46/284 (16%) Query: 237 KALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVM 296 + + +M L Q + G + LE+ R KF++E+++ + EQ+ Sbjct: 606 QVIQDRMSHLEQCFEELSNMAAGARTQLEQSKRLWKFFWEMDEA--ESWIKE---KEQIY 660 Query: 297 ASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQK---MAREPAGSVR 353 +S L + L S + K F D + G +EQI Q+ +AR G + Sbjct: 661 SS----LDYGKDLTSVLILQRKHKAFED---ELRGLDAHLEQIFQEAHGMVARNEFGHPQ 713 Query: 354 DDLGTKEMMEASSLTAWISVPFSRTLKDS-----LEQDLNNMNKFLEKL-RPLSGSEAPR 407 + KE+ ++ + L+D+ + D +++ +L+ R LSG + Sbjct: 714 IEARIKEVSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADDLKAWLQDAHRLLSGED--- 770 Query: 408 LPQDPVGMR------RQLQEELEEVKARLQPYMAEAHEL---------VGWNLEGLRQQL 452 + QD R + EELEE + ++ +A V L+ LR+ Sbjct: 771 VGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSPDVTHRLQALRELY 830 Query: 453 KPYTMDLMEQVALRVQELQEQL---RVVGEDTKAQLLGGVDEAW 493 + ++ Q LR Q LQE L V GE +L G E W Sbjct: 831 Q----QVVAQADLRQQRLQEALDLYTVFGETDACELWMGEKEKW 870
Score = 28.5 bits (62), Expect = 8.1 Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 20/107 (18%) Query: 365 SSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELE 424 + L WIS + D +DL ++N+ L KL+ + +D V +R+ EEL Sbjct: 1389 ADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRV---------EDQVNVRK---EELG 1436 Query: 425 EVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQ 471 E+ A++ P M E ++E +DL+E + R ++L+ Sbjct: 1437 ELFAQV-PSMGEEGGDADLSIE-------KRFLDLLEPLGRRKKQLE 1475
>gi|13431284|sp|Q9UPM8|A4E1_HUMAN Adapter-related protein complex 4 epsilon 1 subunit (Epsilon subunit of AP-4) (AP-4 adapter complex epsilon subunit) Length = 1137 Score = 32.7 bits (73), Expect = 0.43 Identities = 38/124 (30%), Positives = 53/124 (42%), Gaps = 15/124 (12%) Query: 85 MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV------- 137 +ER++ E SL +R HA ELK + +NVE +K L + +D ++ Sbjct: 571 VERLIHEFTISLDTCMRQHAFELK-HLHENVELMKSLLPVDRSCEDLVVDASLSFLDGFV 629 Query: 138 -EELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLA--PLAED 194 E L + APY Q Q E L+ + N E S+S RQ A L D Sbjct: 630 AEGLSQGAAPYKPPHQ----RQEEKLSQEKVLNFEPYGLSFSSSGFTGRQSPAGISLGSD 685 Query: 195 VRGN 198 V GN Sbjct: 686 VSGN 689
>gi|26006960|sp|O75955|FLOT1_HUMAN Flotillin-1 Length = 427 Score = 32.3 bits (72), Expect = 0.56 Identities = 52/245 (21%), Positives = 94/245 (38%), Gaps = 37/245 (15%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLREN 92 DY L K +QK + + +GI+ +A+Q E+V + Sbjct: 159 DYLHSLG---KARTAQVQKDARIGEAEAKRDAGIREAKAKQ------------EKVSAQY 203 Query: 93 ADSLQASLRPHADELKAK---IDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQ 149 ++ + ELK I+ N + L K K Q +EE R + + Sbjct: 204 LSEIEMAKAQRDYELKKAAYDIEVNTRRAQADLAYQLQVAKTK--QQIEEQRVQVQVVER 261 Query: 150 DTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKS 209 Q + Q ++ + +EL+AR+ AE R +L LAE + L E S Sbjct: 262 AQQVAVQEQ------EIARREKELEARVRKPAEAERYKLERLAEAEKSQLIMQAEAEAAS 315 Query: 210 LA--------ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHL 261 + +G + E+ ++ E + + + +A Q++ L +KL A ++ G L Sbjct: 316 VRMRGEAEAFAIGARARAEAEQMAKKAEAF-QLYQEA--AQLDMLLEKLPQVAEEISGPL 372 Query: 262 SFLEK 266 + K Sbjct: 373 TSANK 377
>gi|13124319|sp|O60282|KF5C_HUMAN Kinesin heavy chain isoform 5C (Kinesin heavy chain neuron-specific 2) Length = 957 Score = 32.3 bits (72), Expect = 0.56 Identities = 50/256 (19%), Positives = 105/256 (41%), Gaps = 22/256 (8%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRR--QLTPYAQRMERVLRENAD 94 QL + E L K +++ + + +E E L R + +E+ + + + Sbjct: 656 QLEESQDSLSEELAKLRAQEKMHEVS---FQDKEKEHLTRLQDAEEMKKALEQQMESHRE 712 Query: 95 SLQASLRPHADEL--KAKIDQNVEELKGRLTPYADEF-----KVKIDQTVEELRRSLAPY 147 + Q L DE+ K KI + +L +L ++ K+KI+ E++ Sbjct: 713 AHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLL 772 Query: 148 AQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQ 207 D +E+ L+GL + + + L ++L R+ E + + G + + Sbjct: 773 LNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVE-LDNDDGGGSAAQK 831 Query: 208 KSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFL--- 264 + ++ L +L+Q + ++ V N L ++ +L ++L A V+ S L Sbjct: 832 QKISFLENNLEQLTKVHKQLVRD-----NADLRCELPKLEKRLRATAERVKALESALKEA 886 Query: 265 -EKDLRDKKFWYELED 279 E +RD+K + + D Sbjct: 887 KENAMRDRKRYQQEVD 902
>gi|134973|sp|P16949|STMN1_HUMAN Stathmin (Phosphoprotein p19) (pp19) (Oncoprotein 18) (Op18) (Leukemia-associated phosphoprotein p18) (pp17) (Prosolin) (Metablastin) (Pr22 protein) Length = 149 Score = 32.3 bits (72), Expect = 0.56 Identities = 18/79 (22%), Positives = 37/79 (46%) Query: 171 EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEP 230 EE++ ++ A+ E + A + + + E LQK++ E E+ ++E Sbjct: 48 EEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEA 107 Query: 231 YGENFNKALVQQMEQLRQK 249 EN + ++E+LR+K Sbjct: 108 NKENREAQMAAKLERLREK 126
>gi|20978868|sp|Q9BY12|Z291_HUMAN Zinc finger protein 291 Length = 1399 Score = 32.3 bits (72), Expect = 0.56 Identities = 41/171 (23%), Positives = 76/171 (44%), Gaps = 22/171 (12%) Query: 82 AQRMERVLRENA--DSLQASLRPHADELKAK-IDQNVEELKGRLTPYADEFKVKIDQTVE 138 AQ E + E A ++L+A + H K K +Q + EL+ +E + + D+ V+ Sbjct: 615 AQEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQAR-DEAVQ 673 Query: 139 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGN 198 E +R+L Q E+L MK+ +E A E+ RQ ED Sbjct: 674 ERKRALEAERQARVEEL---------LMKRKEQE------ARIEQQRQEKEKAREDAA-- 716 Query: 199 LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 R ++ LA L + +EE +++++ + + ++Q+EQ ++K Sbjct: 717 -RERARDREERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIEQRKEK 766
>gi|1346343|sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 (Cytokeratin 1) (K1) (CK 1) (67 kDa cytokeratin) (Hair alpha protein) Length = 644 Score = 32.3 bits (72), Expect = 0.56 Identities = 49/251 (19%), Positives = 102/251 (40%), Gaps = 17/251 (6%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLREN 92 + L+N ++ ++ E Q+ +T ++ + L PY + LR Sbjct: 182 EQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRR 241 Query: 93 ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQ-----TVEELRRSLAPY 147 D L++ ELK D VE+ + + Y DE + + T+++ Sbjct: 242 VDQLKSDQSRLDSELKNMQDM-VEDYRNK---YEDEINKRTNAENEFVTIKKDVDGAYMT 297 Query: 148 AQDTQEKLNH---QLEGLTFQMKKNAEELKARISASAEEL---RQRLAPLAEDVRGNLRG 201 D Q KL++ +++ LT + +++ +IS + L R L + Sbjct: 298 KVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQ 357 Query: 202 NTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENF--NKALVQQMEQLRQKLGPHAGDVEG 259 N + QKS AE + EE + +G++ +K + ++ ++ Q+L +V+ Sbjct: 358 NEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKK 417 Query: 260 HLSFLEKDLRD 270 +S L++ + D Sbjct: 418 QISNLQQSISD 428
>gi|27923958|sp|O94833|BPAEA_HUMAN Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin) Length = 5171 Score = 32.3 bits (72), Expect = 0.56 Identities = 57/264 (21%), Positives = 116/264 (43%), Gaps = 32/264 (12%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLREN 92 D +Q N E + T +LKK + E+L++ + AQ + V++ Sbjct: 1242 DLLTQTENRLIGHQEAFMIGDGTVELKKYQS------KQEELQKDMQGSAQALAEVVKNT 1295 Query: 93 ADSLQASLRPHADELKAKIDQNVEELK---GRLTPYADEFKVKIDQTV-----EELRRSL 144 + L+ + + E KA I+Q + E K +L A++ K ++D+ V EE + Sbjct: 1296 ENFLKENGEKLSQEDKALIEQKLNEAKIKCEQLNLKAEQSKKELDKVVTTAIKEETEKVA 1355 Query: 145 A-PYAQDTQEKLNHQLEGLTFQMKKNAEEL----KARISASAEELRQRLAPLA----EDV 195 A ++++ K+ + L+ L+ + K++E K I + ++ A ++V Sbjct: 1356 AVKQLEESKTKIENLLDWLS-NVDKDSERAGTKHKQVIEQNGTHFQEGDGKSAIGEEDEV 1414 Query: 196 RGN-LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALV--QQMEQLRQKLGP 252 GN L + +G + E +L+QQ ++ + + E ++ Q + L +K G Sbjct: 1415 NGNLLETDVDGQVGTTQE---NLNQQYQKVKAQHEKIISQHQAVIIATQSAQVLLEKQGQ 1471 Query: 253 HAGDVEGHLSFLEKDLRDKKFWYE 276 + E L+K++++ K YE Sbjct: 1472 YLSPEEKEK--LQKNMKELKVHYE 1493
>gi|12230855|sp|Q99543|ZRF1_HUMAN Zuotin related factor-1 (M-phase phosphoprotein 11) Length = 568 Score = 32.3 bits (72), Expect = 0.56 Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 19/182 (10%) Query: 32 WDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRE 91 W FS L KE E + + K+ G + + R+ E++ R R L + Sbjct: 224 WREFSYLDEEEKEKAECRDERRWIE--KQNGATRAQ-RKKEEMNRI---------RTLVD 271 Query: 92 NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRS-LAPYAQD 150 NA S ++ +E KAK + E K + E + K Q EL + LA ++ Sbjct: 272 NAYSCDPRIKKFKEEEKAKKEA---EKKAKAEAKRKEQEAKEKQRQAELEAARLAKEKEE 328 Query: 151 TQEKLNHQLEGLTFQMKKNA---EELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQ 207 + + L ++K A E K R S EE+ +++ E+ +R ++ + Sbjct: 329 EEVRQQALLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQASKNTE 388 Query: 208 KS 209 KS Sbjct: 389 KS 390
>gi|417216|sp|P33176|KINH_HUMAN Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC) Length = 963 Score = 32.0 bits (71), Expect = 0.73 Identities = 56/256 (21%), Positives = 111/256 (43%), Gaps = 23/256 (8%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTP--YAQRMERVLRENAD 94 Q +E+V+ L SE QL+ + E E L + T Q +E+ ++ + + Sbjct: 655 QKKRQLEESVDAL--SEELVQLR--AQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRE 710 Query: 95 SLQASLRPHADEL--KAKIDQNVEELKGRLTPYADEFKV---KIDQTVEELRRSLAPYA- 148 + Q + DE+ KAK+ ++++ ++ + +V K+ T +E R L Sbjct: 711 THQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTV 770 Query: 149 -QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQ 207 QD +E+ L+GL + K + L ++L R+ AE + + G + + Sbjct: 771 MQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE-IDSDDTGGSAAQK 829 Query: 208 KSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFL--- 264 + ++ L +L+Q + ++ V N L ++ +L ++L A V+ S L Sbjct: 830 QKISFLENNLEQLTKVHKQLVRD-----NADLRCELPKLEKRLRATAERVKALESALKEA 884 Query: 265 -EKDLRDKKFWYELED 279 E RD+K + + D Sbjct: 885 KENASRDRKRYQQEVD 900
>gi|23503078|sp|Q03252|LAM2_HUMAN Lamin B2 Length = 600 Score = 32.0 bits (71), Expect = 0.73 Identities = 33/157 (21%), Positives = 72/157 (45%), Gaps = 22/157 (14%) Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE---- 138 +R ER L E S Q E K+ Q +EEL+ + +K++++QT + Sbjct: 215 RRHERRLVEVDSSRQ-------QEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLD 267 Query: 139 ------ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLA 192 + A A++ ++ +LE L++Q+ L+ + SA+ + +R+ +A Sbjct: 268 SAKLSSDQNDKAASAAREELKEARMRLESLSYQL----SGLQKQASAAEDRIRELEEAMA 323 Query: 193 EDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVE 229 + R R + ++ + E+ + QQ+ E++ ++ Sbjct: 324 GE-RDKFRKMLDAKEQEMTEMRDVMQQQLAEYQELLD 359
>gi|46396501|sp|Q9BRK4|LZT2_HUMAN Leucine zipper putative tumor suppressor 2 (Protein LAPSER1) Length = 669 Score = 32.0 bits (71), Expect = 0.73 Identities = 51/227 (22%), Positives = 92/227 (40%), Gaps = 17/227 (7%) Query: 419 LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 478 L+ E E+ RL+ E + G + L+QQLK +L+++ + V LRV Sbjct: 425 LEREQRELGPRLEETKWEVCQKSG-EISLLKQQLKESQAELVQKGSELVA-----LRVAL 478 Query: 479 EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKEL--FHPYAESLVSGIGRHVQE---LH 533 + +A L A L + ++R + +EL AE L G+ E L Sbjct: 479 REARATLRVSEGRARGLQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLR 538 Query: 534 RSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXX 593 P A A P L+ + K+ A + ++ +++LR EL R Sbjct: 539 EPPVPPATADPFLLAESDEA---KVQRAAAGVGGSLRAQVERLRVELQRERRRGEEQRDS 595 Query: 594 XPDPQMLSEEVRQ---RLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 637 ++ + ++ R Q Q Y+Q+ R ++QE +++ +L Sbjct: 596 FEGERLAWQAEKEQVIRYQKQLQHNYIQMYRRNRQLEQELQQLSLEL 642
Score = 29.6 bits (65), Expect = 3.6 Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 27/208 (12%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENA--DSLQASL 100 ++ Q+++ QQL + ++ +E QL+ Q E++ R A + Q L Sbjct: 374 EDCAAQAQRAQRAQQLLQLQVFQLQ-QEKRQLQDDFAQLLQEREQLERRCATLEREQREL 432 Query: 101 RPHADELKAKI----------DQNVEELKGRLTPYADEFKVKIDQTVEELRRSL------ 144 P +E K ++ Q ++E + L E V + + E R +L Sbjct: 433 GPRLEETKWEVCQKSGEISLLKQQLKESQAELVQKGSEL-VALRVALREARATLRVSEGR 491 Query: 145 APYAQDTQEKLNHQLEGLTFQMKKNAEELK------ARISASAEELRQRLAPLAEDVRGN 198 A Q+ +LE + +++++ +E + ++ A A LR+ P A Sbjct: 492 ARGLQEAARARELELEACSQELQRHRQEAEQLREKAGQLDAEAAGLREPPVPPATADPFL 551 Query: 199 LRGNTEG-LQKSLAELGGHLDQQVEEFR 225 L + E +Q++ A +GG L QVE R Sbjct: 552 LAESDEAKVQRAAAGVGGSLRAQVERLR 579
>gi|26392576|sp|Q9NUD7|CT96_HUMAN Protein C20orf96 Length = 363 Score = 32.0 bits (71), Expect = 0.73 Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 13/148 (8%) Query: 100 LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQL 159 L A++L AKI++ EE+ T E+ +K Q + L R L Q ++ +L Sbjct: 190 LEQQAEQLNAKIEKTQEEVNFLSTYMDHEYSIKSVQ-ISTLMRQL----QQVKDSQQDEL 244 Query: 160 EGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ 219 + L +K E L +I +++ L+ V R E L + + E L + Sbjct: 245 DDLGEMRRKVLESLSDKIQKKKKKI------LSSVVAETQRPYEEALLQKMWESQDFL-K 297 Query: 220 QVEEFRRRVEPYGENFNKALVQQMEQLR 247 ++ FR ++ + EN L ++E+L+ Sbjct: 298 CMQRFREIIDQFEENM-PVLRAEVEELQ 324
>gi|18266794|sp|O76015|K1M8_HUMAN Keratin, type I cuticular HA8 (Hair keratin, type I HA8) Length = 456 Score = 32.0 bits (71), Expect = 0.73 Identities = 44/221 (19%), Positives = 96/221 (43%), Gaps = 22/221 (9%) Query: 62 GPSGIKGREAEQ---LRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEEL 118 G + + G E E L +L Y +++ ++ +ENA EL+A + + + Sbjct: 96 GENTLNGHEKETMQFLNDRLANYLEKVRQLEQENA------------ELEATLLERSKCH 143 Query: 119 KGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 178 + + P + I++ +++ S A A+ + N +L F++K +E ++ Sbjct: 144 ESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLV 203 Query: 179 ASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKA 238 + + Q+L A + +L E L++ L + +Q+V+ R ++ GE Sbjct: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQL---GEKLRIE 260 Query: 239 L-VQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELE 278 L ++ L + LG E + LE + +D + W++ + Sbjct: 261 LDIEPTIDLNRVLGEMRAQYE---AMLETNRQDVEQWFQAQ 298
Score = 29.6 bits (65), Expect = 3.6 Identities = 37/174 (21%), Positives = 79/174 (45%), Gaps = 27/174 (15%) Query: 90 RENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKID--------QTVEELR 141 + + ++ Q SL+ LK+ +Q V+ L+ +L ++ ++++D + + E+R Sbjct: 221 KADLEAQQESLKEEQLSLKSNHEQEVKILRSQL---GEKLRIELDIEPTIDLNRVLGEMR 277 Query: 142 RS----LAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--------RISASAEEL-RQRL 188 L QD ++ Q EG++ Q +EEL+ R + +A E+ RQ Sbjct: 278 AQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQ 337 Query: 189 APLAEDVRGNLRGNTEGLQKSLAE---LGGHLDQQVEEFRRRVEPYGENFNKAL 239 L + ++ +L + LA+ L ++++Q+ E R +E + + L Sbjct: 338 HTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLL 391
>gi|32699621|sp|Q9NZW0|GOG67_HUMAN Golgi autoantigen golgin-67 (88-kDa Golgi protein) (Gm88 autoantigen) Length = 460 Score = 32.0 bits (71), Expect = 0.73 Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 7/107 (6%) Query: 378 TLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMR-----RQLQEELEEVKARLQP 432 TLK+ + D + + + L L A LP D + + L++ELE V LQ Sbjct: 114 TLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQA 173 Query: 433 YMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 479 E ++ + G +++L+ L EQ R++E +++L+ + E Sbjct: 174 -QVENNQCISLLNRGQKERLREQEERLQEQQE-RLREREKRLQQLAE 218
Score = 29.3 bits (64), Expect = 4.8 Identities = 53/263 (20%), Positives = 99/263 (37%), Gaps = 63/263 (23%) Query: 417 RQLQEELEEVKARLQPYMAEAHELVGWNLEGLR--QQLKP--------------YTMDLM 460 R +EE +++ RLQ EL W+L + Q+ KP + Sbjct: 6 RYFEEESKDLAGRLQRSSQRIGELE-WSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIR 64 Query: 461 EQVALR--VQELQEQLRVVG--EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHP 516 EQ+ L+ V +L+E L+ V D A+ + G W S+ V K+ Sbjct: 65 EQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTH 124 Query: 517 YAESLVSGIGRHVQELHRSVAPHAPASPARL----------------------SRCVQVL 554 E L + R ++ + P APA + + ++C+ +L Sbjct: 125 RVEELERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLL 184 Query: 555 SRKLTLKAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQD 614 +R + + R+Q+ ++LRE R +PQ EE++ ++ Q Sbjct: 185 NRGQKERLREQEERLQEQQERLREREKR--------LQQLAEPQSDLEELKHENKSALQ- 235 Query: 615 TYLQIAAFTRAIDQETEEVQQQL 637 ++Q+ +E+Q++L Sbjct: 236 -----------LEQQVKELQEKL 247
>gi|37537841|sp|Q9BXX0|EMIL2_HUMAN EMILIN 2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (FOAP-10 protein) Length = 1053 Score = 32.0 bits (71), Expect = 0.73 Identities = 27/124 (21%), Positives = 55/124 (44%), Gaps = 17/124 (13%) Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE 171 + ++++K L D K K D+ +EEL + Y ++ L +G T M N E Sbjct: 256 ESGMKDIKSELAEVKDTLKNKSDK-LEELDGKVKGYEGQLRQ-LQEAAQGPTVTMTTN-E 312 Query: 172 ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY 231 +A + + + LR+ L EG+ + LA+L + ++ +++ + Y Sbjct: 313 LYQAYVDSKIDALREELM--------------EGMDRKLADLKNSCEYKLTGLQQQCDDY 358 Query: 232 GENF 235 G ++ Sbjct: 359 GSSY 362
>gi|56749614|sp|Q6NZI2|PTRF_HUMAN Polymerase I and transcript release factor (PTRF protein) (FKSG13 protein) Length = 390 Score = 31.6 bits (70), Expect = 0.96 Identities = 28/140 (20%), Positives = 67/140 (47%), Gaps = 14/140 (10%) Query: 37 QLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERV-LRENADS 95 +LS++ VE + + +++K++G R + ++ + +V REN + Sbjct: 200 ELSSDEAVEVEEVIEESRAERIKRSGL-----RRVDDFKKAFSKEKMEKTKVRTRENLEK 254 Query: 96 LQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAP----YAQDT 151 + + + ++ + +++ + +L RL P E + K+ + ++LR+S P YA+ Sbjct: 255 TRLKTKENLEKTRHTLEKRMNKLGTRLVP--AERREKLKTSRDKLRKSFTPDHVVYAR-- 310 Query: 152 QEKLNHQLEGLTFQMKKNAE 171 + +++ TF +KK E Sbjct: 311 SKTAVYKVPPFTFHVKKIRE 330
>gi|48428272|sp|Q9UIF7|MUTYH_HUMAN A/G-specific adenine DNA glycosylase (MutY homolog) (hMYH) Length = 546 Score = 31.6 bits (70), Expect = 0.96 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 2/55 (3%) Query: 178 SASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYG 232 SAS EE+ Q A L RG R EG +K + ELGGH+ + E ++ + G Sbjct: 161 SASLEEVNQLWAGLGYYSRG--RRLQEGARKVVEELGGHMPRTAETLQQLLPGVG 213
>gi|13431713|sp|Q9NQX4|MYO5C_HUMAN Myosin Vc (Myosin 5C) Length = 1742 Score = 31.6 bits (70), Expect = 0.96 Identities = 53/228 (23%), Positives = 86/228 (37%), Gaps = 50/228 (21%) Query: 46 VEHLQKSELTQQLKKTGPSGI--KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPH 103 VE +QK E + T KG+ + Q+ L + +Q L+ Sbjct: 923 VEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEK 982 Query: 104 ADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLT 163 +ELK K+D ++L D EE +R L L E T Sbjct: 983 TEELKEKMDNLTKQLFD-------------DVQKEERQRML----------LEKSFELKT 1019 Query: 164 FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE 223 +K + LK I A +E Q L V G ++GL+ +A L + + + E Sbjct: 1020 QDYEKQIQSLKEEIKALKDEKMQ----LQHLVEGE-HVTSDGLKAEVARLSKQV-KTISE 1073 Query: 224 FRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDK 271 F + +E L+Q QK+ DVE H+ ++++R+K Sbjct: 1074 FEKEIE---------LLQ-----AQKI-----DVEKHVQSQKREMREK 1102
>gi|12643814|sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (PLC-beta-1) (Phospholipase C-beta-1) (PLC-I) (PLC-154) Length = 1216 Score = 31.6 bits (70), Expect = 0.96 Identities = 43/238 (18%), Positives = 100/238 (42%), Gaps = 25/238 (10%) Query: 36 SQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKG-------REAEQLRRQLTPYAQRMERV 88 S L+ + +E L++ + +L+K +K + + ++ T Y + Sbjct: 900 SVLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDY 959 Query: 89 LRENA--------DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEEL 140 LR A DS + S D + I+Q++ L +T + K K Q + L Sbjct: 960 LRRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNL 1019 Query: 141 RRSLAPYAQDTQEKLNH------QLEGLTFQMKKNA-EELKARISASAEELRQRLAPLAE 193 R+ Y + +K H +L + + + N ++LK +EL++++ + Sbjct: 1020 RQE--QYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQ 1077 Query: 194 DVRGNLRGNTEG-LQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 + + + +++ E+ Q+V ++ +R+E + LV++ +++RQ++ Sbjct: 1078 EKITEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQI 1135
>gi|56405387|sp|Q9UPN3|MACF1_HUMAN Microtubule-actin crosslinking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin 1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620) Length = 5430 Score = 31.6 bits (70), Expect = 0.96 Identities = 56/290 (19%), Positives = 107/290 (36%), Gaps = 38/290 (13%) Query: 417 RQLQEELEEVKARLQPYMAEAHELVGW------NLEGLRQQLKPYTMDLMEQVALRVQEL 470 R+L+EE + V+ Q ++ + EL+GW N +G + +E+ L Q L Sbjct: 1411 RRLEEEEKVVEEEKQEHVEKVKELLGWVSTLARNTQGKATSSETKESTDIEKAILEQQVL 1470 Query: 471 QEQLRV----VGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIG 526 E+L V E K + L + + ++ + +H L G Sbjct: 1471 SEELTTKKEQVSEAIKTSQIFLAKHGHKLSEKEKKQISEQLNALNKAYH----DLCDGSA 1526 Query: 527 RHVQELHRSVAPHAPASPARLSR--CVQVLSRKLTLKAKALHA--------------RIQ 570 +Q+L +A + + C Q L + +A A +Q Sbjct: 1527 NQLQQLQSQLAHQTEQKTLQKQQNTCHQQLEDLCSWVGQAERALAGHQGRTTQQDLSALQ 1586 Query: 571 QNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQ-----AFRQDTYLQIAAFTRA 625 +N L++ D + EE + +L A R+ + Q A Sbjct: 1587 KNQSDLKDLQDDIQNRATSFATVVKDIEGFMEENQTKLSPRELTALREKLH-QAKEQYEA 1645 Query: 626 IDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDIT 675 + +ET Q++L SA E +++ + K L++ + ++D L + +T Sbjct: 1646 LQEETRVAQKELEEAVT--SALQQETEKSKAAKELAENKKKIDALLDWVT 1693
Score = 28.9 bits (63), Expect = 6.2 Identities = 63/296 (21%), Positives = 109/296 (36%), Gaps = 48/296 (16%) Query: 381 DSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHEL 440 DSL+ + +EKL + + P + Q+ + +QLQEEL E + ++ A ++ Sbjct: 1942 DSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDI 2001 Query: 441 VGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQ 500 + +EG + + + + Q L L A+ + +A A Q +Q Sbjct: 2002 M--EIEGEPAPDHRHVQETTDSILSHFQSLSYSL--------AERSSLLQKAIAQSQSVQ 2051 Query: 501 SRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTL 560 + ESL+ IG Q L + LS V + + Sbjct: 2052 ESL---------------ESLLQSIGEVEQNLEGK-------QVSSLSSGVIQEALATNM 2089 Query: 561 KAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIA 620 K K AR + +L+ RE ++R +L ++ + Q F Q Q Sbjct: 2090 KLKQDIARQKSSLEATREMVTRFMETADSTTAA-----VLQGKLAEVSQRFEQLCLQQ-- 2142 Query: 621 AFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITH 676 QE E ++L P + + QQ K S++ A + +DITH Sbjct: 2143 -------QEKESSLKKLLPQAEMFEHLSGKLQQFMENK--SRMLASGNQPDQDITH 2189
>gi|48474780|sp|P78386|K2H5_HUMAN Keratin, type II cuticular HB5 (Hair keratin, type II HB5) Length = 507 Score = 31.6 bits (70), Expect = 0.96 Identities = 34/153 (22%), Positives = 67/153 (43%), Gaps = 20/153 (13%) Query: 92 NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDT 151 N D + A ++ D++ ++ + E + +E K + + E LRR+ ++ Sbjct: 287 NMDCIIAEIKAQYDDVASR---SRAEAESWYRSKCEEMKATVIRHGETLRRT-----KEE 338 Query: 152 QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLA 211 +LN ++ LT +++ NA+ +A++ A+ E Q+ D R LA Sbjct: 339 INELNRMIQRLTAEIE-NAKCQRAKLEAAVAEAEQQGEAALSDAR-----------CKLA 386 Query: 212 ELGGHLDQQVEEFRRRVEPYGENFNKALVQQME 244 EL G L + ++ ++ Y E N L +E Sbjct: 387 ELEGALQKAKQDMACLLKEYQEVMNSKLGLDIE 419
>gi|30316105|sp|Q96PK2|MAC4_HUMAN Microtubule-actin crosslinking factor 1, isoform 4 Length = 5938 Score = 31.6 bits (70), Expect = 0.96 Identities = 34/161 (21%), Positives = 69/161 (42%), Gaps = 30/161 (18%) Query: 113 QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE 172 Q E+LK + E K ++D +++ ++ +AQD + N Q+ L +++++ ++ Sbjct: 1964 QQYEDLKQPMA----ERKAQLDALAFDIQFFISEHAQDLSPQQNRQMLRLLNELQRSFQD 2019 Query: 173 LKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYG 232 + + +A + L+ L + + E L K+L + QQ+E+ Sbjct: 2020 ILEQTAAQVDALQGHLQQMEQ----------EALVKTLQKQQNTCHQQLED--------- 2060 Query: 233 ENFNKALVQQMEQLRQKLGPHAG-DVEGHLSFLEKDLRDKK 272 L + Q + L H G + LS L+K+ D K Sbjct: 2061 ------LCSWVGQAERALAGHQGRTTQQDLSALQKNQSDLK 2095
Score = 28.9 bits (63), Expect = 6.2 Identities = 63/296 (21%), Positives = 109/296 (36%), Gaps = 48/296 (16%) Query: 381 DSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHEL 440 DSL+ + +EKL + + P + Q+ + +QLQEEL E + ++ A ++ Sbjct: 2444 DSLQAWMQACEANVEKLLSDTVASDPGVLQEQLATTKQLQEELAEHQVPVEKLQKVARDI 2503 Query: 441 VGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQ 500 + +EG + + + + Q L L A+ + +A A Q +Q Sbjct: 2504 M--EIEGEPAPDHRHVQETTDSILSHFQSLSYSL--------AERSSLLQKAIAQSQSVQ 2553 Query: 501 SRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTL 560 + ESL+ IG Q L + LS V + + Sbjct: 2554 ESL---------------ESLLQSIGEVEQNLEGK-------QVSSLSSGVIQEALATNM 2591 Query: 561 KAKALHARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIA 620 K K AR + +L+ RE ++R +L ++ + Q F Q Q Sbjct: 2592 KLKQDIARQKSSLEATREMVTRFMETADSTTAA-----VLQGKLAEVSQRFEQLCLQQ-- 2644 Query: 621 AFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITH 676 QE E ++L P + + QQ K S++ A + +DITH Sbjct: 2645 -------QEKESSLKKLLPQAEMFEHLSGKLQQFMENK--SRMLASGNQPDQDITH 2691
>gi|51316936|sp|Q9UPW8|U13A_HUMAN Unc-13 homolog A (Munc13-1) Length = 1157 Score = 31.6 bits (70), Expect = 0.96 Identities = 38/177 (21%), Positives = 73/177 (41%), Gaps = 18/177 (10%) Query: 33 DYFSQLSNNAKEAVEHLQKSE------LTQQLKKTGPSGIKGREAEQLRRQLTPYAQRME 86 D FSQL N + E ++ L+ + ++ KT S + + A+ + + Y + + Sbjct: 645 DVFSQL-NQSFEIIKKLECPDPQIVGHYMRRFAKT-ISNVLLQYADIISKDFASYCSKEK 702 Query: 87 R----VLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 +L N L+ L + + K EL + E +VK++ ++EL R Sbjct: 703 EKVPCILMNNTQQLRVQLEKMFEAMGGK------ELDAEASDILKELQVKLNNVLDELSR 756 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNL 199 A Q E+ Q+ + Q+K + S+ A++ L P+ + + NL Sbjct: 757 VFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNVLQPIMDLLDSNL 813
>gi|25091514|sp|O43895|XPP2_HUMAN Xaa-Pro aminopeptidase 2 precursor (X-Pro aminopeptidase 2) (Membrane-bound aminopeptidase P) (Membrane-bound APP) (Membrane-bound AmP) (mAmP) (Aminoacylproline aminopeptidase) Length = 674 Score = 31.2 bits (69), Expect = 1.3 Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 12/74 (16%) Query: 373 VPFSRTLKD-SL--EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKAR 429 VP+ R L D SL + L +N++ + +R G E RRQL EE E ++ Sbjct: 594 VPYDRNLIDVSLLSPEHLQYLNRYYQTIREKVGPEL---------QRRQLLEEFEWLQQH 644 Query: 430 LQPYMAEAHELVGW 443 +P A A + W Sbjct: 645 TEPLAARAPDTASW 658
>gi|12643358|sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 (Lymphocyte-oriented kinase) Length = 968 Score = 31.2 bits (69), Expect = 1.3 Identities = 20/58 (34%), Positives = 36/58 (62%), Gaps = 2/58 (3%) Query: 418 QLQEELEEVKARLQP-YMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQL 474 QLQE + VK +L+ Y + HEL+ + E R+Q++ Y ++EQ+ +R Q+ + +L Sbjct: 750 QLQERHQLVKQQLKDQYFLQRHELLRKH-EKEREQMQRYNQRMIEQLKVRQQQEKARL 806
>gi|543742|sp|P35609|AAC2_HUMAN Alpha-actinin 2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross linking protein) Length = 894 Score = 31.2 bits (69), Expect = 1.3 Identities = 42/227 (18%), Positives = 95/227 (41%), Gaps = 43/227 (18%) Query: 32 WDYFSQLSNNAKEAVEHLQK-SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR 90 WD L+ +EA+E ++K E QL + ++ P+ ME + Sbjct: 490 WDRLGTLTQKRREALERMEKLLETIDQLHL------------EFAKRAAPFNNWMEGAME 537 Query: 91 E--------NADSLQASLRPHADELKAKID------QNVEELKGRLTPYADEFKVKIDQT 136 + + + +Q+ + H ++ KA + Q++ ++ + + ++I Sbjct: 538 DLQDMFIVHSIEEIQSLITAH-EQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRIS-- 594 Query: 137 VEELRRSLAPYAQDTQEKLN---HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAE 193 S PY+ T ++L +++ L ++ +E AR A+ E LR++ A A Sbjct: 595 ------SSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHAN-ERLRRQFAAQAN 647 Query: 194 DVRGNLRGNTEGLQKSLAELGGHLD---QQVEEFRRRVEPYGENFNK 237 + ++ E + +S ++ G L+ Q++++ + Y N +K Sbjct: 648 AIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDK 694
>gi|6175045|sp|Q13277|STX3_HUMAN Syntaxin-3 Length = 289 Score = 31.2 bits (69), Expect = 1.3 Identities = 32/145 (22%), Positives = 64/145 (44%), Gaps = 18/145 (12%) Query: 100 LRPHADELKAKI-----DQNVEELKGRLTPYADEFKVKIDQT----------VEELRR-- 142 ++ ++LKAK D + E+ T + DEF +I++T VEE ++ Sbjct: 1 MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGN 202 S+ A + K LE LT ++KK A ++ ++ + + + + + D+R + Sbjct: 61 SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIR-KSQ 119 Query: 203 TEGLQKSLAELGGHLDQQVEEFRRR 227 L + E+ ++ +FR R Sbjct: 120 HSVLSRKFVEVMTKYNEAQVDFRER 144
>gi|6016414|sp|Q14532|K1M2_HUMAN Keratin, type I cuticular HA2 (Hair keratin, type I HA2) Length = 448 Score = 31.2 bits (69), Expect = 1.3 Identities = 52/227 (22%), Positives = 95/227 (41%), Gaps = 38/227 (16%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKI---DQNVEELKGRLT-PY 125 EAE RQL R + ++ +A L + LK ++ +N EE G L Sbjct: 186 EAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQL 245 Query: 126 ADEFKVKID--------QTVEELRRSLAPYAQ----DTQEKLNHQLEGLTFQMKKNAEEL 173 D +++D + +EE+R + D +E N Q+E L Q+ ++E+L Sbjct: 246 GDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQL 305 Query: 174 KARISASAEELRQRLAPLAEDVRG--NLRGNTEG-LQKSLAELGGHLDQ----------Q 220 + + +LR+ + L +++ +LR + E L +S A L Q Q Sbjct: 306 Q-NYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQ 364 Query: 221 VEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKD 267 + E R +E + + Q + +R +L G++ + S LE + Sbjct: 365 LAEIRAELERQNQEY-----QVLLDVRARL---EGEINTYRSLLESE 403
>gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin) Length = 8797 Score = 31.2 bits (69), Expect = 1.3 Identities = 44/225 (19%), Positives = 91/225 (40%), Gaps = 18/225 (8%) Query: 39 SNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQA 98 S+ A+E V +++ +QL + +R + + Q +E L + + + Sbjct: 6022 SSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQ 6081 Query: 99 S-----LRPHADELKAKIDQNVEELKGRLTPYADEFKVKID-----QTVEELRRSLAPYA 148 R ADEL + + L L+P + ++ + E+ + + + Sbjct: 6082 EQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALS 6141 Query: 149 QDTQEKLNHQLEGLTFQMKKNAEELKA---RISASAEELRQRLAPLAEDVRGNLRGNTEG 205 + + N LEG K AE+L R+ S EL++ L D + N++G + Sbjct: 6142 ELSVHNENLLLEGKA-HTKDEAEQLAGKLRRLKGSLLELQRAL----HDKQLNMQGTAQE 6196 Query: 206 LQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKL 250 ++S +L V+E+ + ++ +QQ ++L Q+L Sbjct: 6197 KEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQEL 6241
Score = 29.3 bits (64), Expect = 4.8 Identities = 13/47 (27%), Positives = 26/47 (55%) Query: 453 KPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGL 499 K T+D + Q L++ + + + A+ LG ++++W +LQGL Sbjct: 6963 KQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGL 7009
>gi|25452905|sp|Q9H501|CT06_HUMAN Hypothetical protein C20orf6 Length = 851 Score = 30.8 bits (68), Expect = 1.6 Identities = 30/123 (24%), Positives = 53/123 (43%), Gaps = 4/123 (3%) Query: 34 YFSQLSNNAKEAVEHLQKSE--LTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRE 91 Y + S + +E E LQ + ++ KT S E RQL Q E+ +E Sbjct: 539 YLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKE 598 Query: 92 NADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDT 151 N ++ P E ++ +N E K +LTP+ + K ++ + L+R A++ Sbjct: 599 NDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEK--KRLKRKQKALAEEA 656 Query: 152 QEK 154 E+ Sbjct: 657 SEE 659
>gi|38605459|sp|Q9C035|TRM5_HUMAN Tripartite motif protein 5 (RING finger protein 88) Length = 493 Score = 30.8 bits (68), Expect = 1.6 Identities = 26/119 (21%), Positives = 47/119 (39%), Gaps = 5/119 (4%) Query: 126 ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR 185 A E++VK+ +E LR+ Q E+L + K + K + A E+LR Sbjct: 135 AREYQVKLQAALEMLRQK-----QQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLR 189 Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQME 244 L + NL E + KSL + QQ + R + ++++ ++ Sbjct: 190 DILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELLQ 248
>gi|13959419|sp|Q9UJF2|NGAP_HUMAN Ras GTPase-activating protein nGAP (RAS protein activator like 1) Length = 1139 Score = 30.8 bits (68), Expect = 1.6 Identities = 34/143 (23%), Positives = 68/143 (47%), Gaps = 15/143 (10%) Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE 171 +QN++E K +A++++ +I + E LR S E+ +L QM+K Sbjct: 977 EQNLDEAK-----HAEKYEQEITKLKERLRVS-----SRRLEEYERRLLVQEQQMQKLLL 1026 Query: 172 ELKARISASAEELRQRLAPLAEDVR---GNLRGNTEGLQKSLAELGGHLD--QQVEEFRR 226 E KAR+ S E LR++ ++ L E L+K AE+ +D Q++ + + Sbjct: 1027 EYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQE 1086 Query: 227 RVEPYGENFNKALVQQMEQLRQK 249 + ++ N L+ + Q++++ Sbjct: 1087 KRIVSLDSANTRLMSALTQVKER 1109
>gi|2498204|sp|Q05682|CALD1_HUMAN Caldesmon (CDM) Length = 793 Score = 30.8 bits (68), Expect = 1.6 Identities = 97/516 (18%), Positives = 198/516 (38%), Gaps = 82/516 (15%) Query: 36 SQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRR--QLTPYAQRMERVLRENA 93 +Q+ +E Q+ + LK S + ++ E+ + + ++ME +E A Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA 265 Query: 94 DSLQASLRPHADE-LKAKIDQNVEELKGRLTPY----ADEFKVKIDQTVEELRRSLAPYA 148 ++ +A L E +KA+ D+ + + + R+ A E + + + E +R A Sbjct: 266 EAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAA 325 Query: 149 QDTQ------EKLNHQLEGLTFQMKKNAEE---LKARISASAEELRQRLAPLAEDVRGNL 199 ++ Q ++ + + + + K+ AEE +K +AEE ++ A E + Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEE 385 Query: 200 RGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ-LRQKLGPHAGDV- 257 + + L++ + + E+ +++E N KA +++ + +K G G Sbjct: 386 QKRNKQLEEKKRAMQ-ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444 Query: 258 --------EGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAVLTWALAL 309 E +F +++++D+K + E E+V + M Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEP------------KEEVKSFM---------- 482 Query: 310 LSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTA 369 +KGF + SQ +G+ + H + P G R + TKE A + A Sbjct: 483 -------DRKKGFTEVKSQ-NGEFMTHKLKHTENTFSRPGG--RASVDTKEAEGAPQVEA 532 Query: 370 WISVPFSRTLKDSLEQD---------------LNNMNKFLEKLRPLSGSEAPRLPQDPVG 414 + R + E + L + K E+ R + E R Q+ Sbjct: 533 GKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEAD 592 Query: 415 MRRQLQEELEEVKARLQPYMAEAHE-LVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQ 473 + + +EE +K ++ AEA E +GL KP+ + +L+++E E Sbjct: 593 RKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEF 652 Query: 474 LRVVGEDTKAQLLGGVDEAW--ALLQGLQSRVVHHT 507 L + Q GV A++ + SR+ +T Sbjct: 653 L-----NKSVQKSSGVKSTHQAAIVSKIDSRLEQYT 683
>gi|122824|sp|P13196|HEM1_HUMAN 5-aminolevulinate synthase, nonspecific, mitochondrial precursor (5-aminolevulinic acid synthase) (Delta-aminolevulinate synthase) (Delta-ALA synthetase) (ALAS-H) (OK/SW-cl.121) Length = 640 Score = 30.8 bits (68), Expect = 1.6 Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 4/126 (3%) Query: 66 IKGREAEQLRRQLTPYAQRMERVLRENADSL---QASLRPHADELKAKIDQNVEELKGRL 122 +K E LRRQ + M ++L + + + + P AK + +EL R Sbjct: 492 LKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRH 551 Query: 123 TPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE 182 Y EEL R +AP T + +N+ LE L K+ ELK SA Sbjct: 552 NIYVQAINYPTVPRGEELLR-IAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECN 610 Query: 183 ELRQRL 188 R+ L Sbjct: 611 FCRRPL 616
>gi|8928247|sp|Q15185|TEBP_HUMAN Telomerase-binding protein p23 (Hsp90 co-chaperone) (Progesterone receptor complex p23) Length = 160 Score = 30.8 bits (68), Expect = 1.6 Identities = 13/43 (30%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 370 WISVPFS--RTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQ 410 W+SV F+ + +D ++D++N ++F E + + G E LP+ Sbjct: 98 WLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPE 140
>gi|22096362|sp|P54252|MJD1_HUMAN Machado-Joseph disease protein 1 (Ataxin-3) (Spinocerebellar ataxia type 3 protein) Length = 376 Score = 30.8 bits (68), Expect = 1.6 Identities = 19/86 (22%), Positives = 45/86 (52%), Gaps = 3/86 (3%) Query: 166 MKKNAEELKARISASAEEL--RQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEE 223 + ++ E+L+ ++ S +E+ A L ++ +++G++ + + + + G + EE Sbjct: 222 LDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSG-TNLTSEE 280 Query: 224 FRRRVEPYGENFNKALVQQMEQLRQK 249 R+R E Y E + QQ +Q +Q+ Sbjct: 281 LRKRREAYFEKQQQKQQQQQQQQQQQ 306
Score = 30.0 bits (66), Expect = 2.8 Identities = 26/136 (19%), Positives = 56/136 (41%), Gaps = 14/136 (10%) Query: 47 EHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE 106 + + K++L + L+ SG+ + E L+R L R E + + L+ +++ Sbjct: 202 QRVHKTDLERMLEANDGSGMLDEDEEDLQRALA--LSRQEIDMEDEEADLRRAIQLSMQG 259 Query: 107 LKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM 166 I Q++ + G + T EELR+ Y + Q+K Q + Q Sbjct: 260 SSRNISQDMTQTSGT------------NLTSEELRKRREAYFEKQQQKQQQQQQQQQQQQ 307 Query: 167 KKNAEELKARISASAE 182 ++ ++ + + S + Sbjct: 308 QQQQQQQQQQRDLSGQ 323
>gi|21362900|sp|Q9BYV6|RN29_HUMAN RING finger protein 29 (Muscle specific ring finger protein 2) (MuRF2) Length = 436 Score = 30.4 bits (67), Expect = 2.1 Identities = 50/224 (22%), Positives = 94/224 (41%), Gaps = 29/224 (12%) Query: 36 SQLSNNAKEAVE--HLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENA 93 SQL + K E QK EL ++ GI E+ + ++T Q + R E Sbjct: 175 SQLEDTCKTIEECCRKQKQELCEKFDYL--YGI----LEERKNEMT---QVITRTQEEKL 225 Query: 94 DSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKID-QTVEELRRSLAPYAQDTQ 152 + ++A ++ ++D L +NV +L + DE ++ + Q + L + ++ ++ Q Sbjct: 226 EHVRALIKKYSDHL-----ENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQ 280 Query: 153 -EKLNHQLEGLT-FQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSL 210 EK+ H E + F + N EE ++ + + ED EG ++ Sbjct: 281 MEKIEHGYENMNHFTVNLNREE----------KIIREIDFYREDEDEEEEEGGEGEKEGE 330 Query: 211 AELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHA 254 E+GG + E + E GE+ N ++ Q+ + P A Sbjct: 331 GEVGGEAVEVEEVENVQTEFPGEDENPEKASELSQVELQAAPGA 374
>gi|20455319|sp|Q92994|TF3B_HUMAN Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (hBRF) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) (TAF3B2) Length = 677 Score = 30.4 bits (67), Expect = 2.1 Identities = 21/96 (21%), Positives = 48/96 (50%), Gaps = 5/96 (5%) Query: 106 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ 165 +L+ + + +EE++G ++ Y D +++++ + + + LA A+D + L + Sbjct: 305 QLEQVLSKKLEEVEGEISSYQDAIEIELENSRPKAKGGLASLAKDGSTE--DTASSLCGE 362 Query: 166 MKKNAEELKARISASAEELRQRL---APLAEDVRGN 198 EEL+A S ++L + L AP + + G+ Sbjct: 363 EDTEDEELEAAASHLNKDLYRELLGGAPGSSEAAGS 398
>gi|37999757|sp|Q96PP8|GBP5_HUMAN Interferon-induced guanylate-binding protein 5 (GTP-binding protein 5) (Guanine nucleotide-binding protein 5) (GBP-TA antigen) (UNQ2427/PRO4987) Length = 586 Score = 30.4 bits (67), Expect = 2.1 Identities = 34/123 (27%), Positives = 57/123 (46%), Gaps = 15/123 (12%) Query: 42 AKEAVEH--LQKSE-LTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQA 98 +KE+V H LQ + LT+ KK + +K EAE+ AQR+ + R+N +Q Sbjct: 465 SKESVSHAILQTDQALTETEKKKKEAQVKA-EAEKAE------AQRLAAIQRQNEQMMQE 517 Query: 99 SLRPHADELK----AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEK 154 R H ++++ AK + E+ K + E ++ T + RSL Q Q Sbjct: 518 RERLHQEQVRQMEIAKQNWLAEQQKMQ-EQQMQEQAAQLSTTFQAQNRSLLSELQHAQRT 576 Query: 155 LNH 157 +N+ Sbjct: 577 VNN 579
>gi|134461|sp|P05060|SCG1_HUMAN Secretogranin-1 precursor (Secretogranin I) (SgI) (Chromogranin B) (CgB) [Contains: GAWK peptide; CCB peptide] Length = 677 Score = 30.4 bits (67), Expect = 2.1 Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 139 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGN 198 E R+ L +D ++K + E F+++ + A + + + AP ED++G Sbjct: 56 ECRQVLKTSRKDVKDKETTENENTKFEVRLLRDPADASEAHESSSRGEAGAPGEEDIQGP 115 Query: 199 LRGNTEGLQKSLAELGGHLDQQVEE 223 + +TE AE GGH ++ +E Sbjct: 116 TKADTE----KWAEGGGHSRERADE 136
>gi|126366|sp|P07942|LMB1_HUMAN Laminin beta-1 chain precursor (Laminin B1 chain) Length = 1786 Score = 30.4 bits (67), Expect = 2.1 Identities = 31/137 (22%), Positives = 61/137 (44%), Gaps = 8/137 (5%) Query: 135 QTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA------EELRQRL 188 Q + L S+ ++E L + + ++ ++++N EELK + + ++ E++ + Sbjct: 1621 QGTQNLLTSIESETAASEETLFNASQRIS-ELERNVEELKRKAAQNSGEAEYIEKVVYTV 1679 Query: 189 APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ 248 AEDV+ L G + K + L ++ + RR+ E +N K L+ Q Q Sbjct: 1680 KQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEML-QNEAKTLLAQANSKLQ 1738 Query: 249 KLGPHAGDVEGHLSFLE 265 L E + +LE Sbjct: 1739 LLKDLERKYEDNQRYLE 1755
>gi|32469733|sp|Q8IWJ2|GCC2_HUMAN GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW-11) Length = 1583 Score = 30.4 bits (67), Expect = 2.1 Identities = 29/139 (20%), Positives = 59/139 (42%), Gaps = 3/139 (2%) Query: 132 KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPL 191 +I+ EL + Y++D + L QLE + +E+LK ++E+ ++L Sbjct: 29 EIENLKNELMAVRSKYSED-KANLQKQLEEAMNTQLELSEQLK--FQNNSEDNVKKLQEE 85 Query: 192 AEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLG 251 E +R LQK L + V + + +E +++ K + E+L Q Sbjct: 86 IEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKA 145 Query: 252 PHAGDVEGHLSFLEKDLRD 270 H +V+ + +E ++ Sbjct: 146 IHQEEVKELMCQIEASAKE 164
>gi|25453223|sp|Q9ULU4|PKCB_HUMAN Protein kinase C binding protein 1 (Rack7) (Cutaneous T-cell lymphoma associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain containing protein 8) Length = 1186 Score = 30.4 bits (67), Expect = 2.1 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 10/148 (6%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENAD-SLQASLR 101 ++AV+ +Q+ E+TQ + + + ++ L +T V NAD + + Sbjct: 864 RQAVKAVQQKEITQSPSTSTITLVTSTQSSPL---VTSSGSMSTLVSSVNADLPIATASA 920 Query: 102 PHADELKAKIDQNVEELKGRLTP-YADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLE 160 A ++ + ++ +KG +T Y D K T+ E+RR EKL + Sbjct: 921 DVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEI-----EKLQWLHQ 975 Query: 161 GLTFQMKKNAEELKARISASAEELRQRL 188 +MK N E A + S E+ R RL Sbjct: 976 QELSEMKHNLELTMAEMRQSLEQERDRL 1003
>gi|34098604|sp|Q8TD16|BCD2_HUMAN Cytoskeleton-like bicaudal D protein homolog 2 Length = 824 Score = 30.4 bits (67), Expect = 2.1 Identities = 35/121 (28%), Positives = 51/121 (42%), Gaps = 18/121 (14%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEF 129 E +QLR LT N S L A ELK +I+QNVE +GRL E+ Sbjct: 124 ELKQLRNVLT------------NTQSENERLASVAQELK-EINQNVEIQRGRLRDDIKEY 170 Query: 130 K---VKIDQTVEELRRSLAPYAQDTQEKLNHQL--EGLTFQMKKNAEELKARISASAEEL 184 K ++ Q EL + +Q+ EGL ++K+ EE + S + + Sbjct: 171 KFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAI 230 Query: 185 R 185 R Sbjct: 231 R 231
>gi|128147|sp|P07197|NFM_HUMAN Neurofilament triplet M protein (160 kDa neurofilament protein) (Neurofilament medium polypeptide) (NF-M) (Neurofilament 3) Length = 916 Score = 30.4 bits (67), Expect = 2.1 Identities = 27/170 (15%), Positives = 72/170 (42%), Gaps = 10/170 (5%) Query: 88 VLRENADSLQASLRPHADELKAKIDQNVEELKGRL------TPYADEFKVKIDQTVEELR 141 +++ D SL+ L++ ++ V +L ++ D K I ++E+R Sbjct: 215 LVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIR 274 Query: 142 RSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL---RQRLAPLAEDVRGN 198 L ++ + + ++ + AE+ K I ++ EE+ R++L + ++ + Sbjct: 275 SQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELE-S 333 Query: 199 LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQ 248 +RG E L++ L+++ + + ++ ++ + LR+ Sbjct: 334 VRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLRE 383
>gi|8134735|sp|O60664|M6P1_HUMAN Mannose-6-phosphate receptor binding protein 1 (Cargo selection protein TIP47) (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Placental protein 17) Length = 434 Score = 30.4 bits (67), Expect = 2.1 Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 16/164 (9%) Query: 336 VEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNK--- 392 VE+ QQ + S+ T +M+ A+ + S P +T+ D+ E+ + + Sbjct: 16 VEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHVKTVCDAAEKGVRTLTAAAV 75 Query: 393 -----FLEKLRP--LSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNL 445 L KL P S SE D +L+E L ++ + +A+ ELV + Sbjct: 76 SGAQPILSKLEPQIASASEYAHRGLD------KLEENLPILQQPTEKVLADTKELVSSKV 129 Query: 446 EGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGV 489 G ++ + + Q++ V + ++ + TK+ + GGV Sbjct: 130 SGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGV 173
Score = 30.0 bits (66), Expect = 2.8 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 18/159 (11%) Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTV---EE 139 QR E+ SL LR HA E ++ +L+ A E +++ Q + E Sbjct: 229 QRQEQSYFVRLGSLSERLRQHAYE------HSLGKLRAT-KQRAQEALLQLSQALSLMET 281 Query: 140 LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKA--RISASAEELRQRLAPLAEDVRG 197 +++ + + QEKL HQ+ + N ++L+ + E++ R + D+ Sbjct: 282 VKQGVDQKLVEGQEKL-HQM-----WLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQ 335 Query: 198 NLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFN 236 L+ L S+ L ++ QV++ RR+VE F+ Sbjct: 336 QLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFS 374
>gi|41688524|sp|Q9UMD9|CA1G_HUMAN Collagen alpha 1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2) Length = 1497 Score = 30.4 bits (67), Expect = 2.1 Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 8/79 (10%) Query: 128 EFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEEL--- 184 + K ++D+ +E +RRS+ PY +L+G+ + +++ S S EEL Sbjct: 494 KLKARVDE-LERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGLH-SDSQEELWMF 551 Query: 185 -RQRLAPLAEDVRGNLRGN 202 R++L + E GNLRG+ Sbjct: 552 VRKKL--MMEQENGNLRGS 568
>gi|1708851|sp|P55268|LMB2_HUMAN Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain) Length = 1798 Score = 30.4 bits (67), Expect = 2.1 Identities = 84/343 (24%), Positives = 136/343 (39%), Gaps = 37/343 (10%) Query: 189 APLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQ------Q 242 A A+ G R LQ++LAE GG + +V E RR+ + AL + Q Sbjct: 1446 AATADLALGRARHTQAELQRALAE-GGSILSRVAETRRQASEAQQRAQAALDKANASRGQ 1504 Query: 243 MEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTCPVGGLPPPVFSEQVMASMAAV 302 +EQ Q+L V+ FL ++ D E+ T V L P +EQ+ +A Sbjct: 1505 VEQANQELQELIQSVK---DFLNQEGADPDS-IEMVAT-RVLELSIPASAEQIQ-HLAGA 1558 Query: 303 LTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMM 362 + + L+ A AR T GD R EQ+ Q AR D+ E + Sbjct: 1559 IAERVRSLADVDAILAR---------TVGDVRRAEQLLQD--ARRARSWAEDEKQKAETV 1607 Query: 363 EASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRP-LSGSEAPRLPQDPVGMRRQLQE 421 +A+ A + ++ D + + L +++ ++G+E R RQL Sbjct: 1608 QAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAE--RALSSAGERARQLDA 1665 Query: 422 ELEEVKARL--QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR--VV 477 LE +K + A E + +G Q+ + + V+ L E+ V+ Sbjct: 1666 LLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVL 1725 Query: 478 GEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAES 520 +A+ L DEA LLQ Q ++ R +EL Y E+ Sbjct: 1726 AAQARAEQLR--DEARDLLQAAQDKL----QRLQELEGTYEEN 1762
>gi|23396777|sp|Q9Y6Q9|NCOA3_HUMAN Nuclear receptor coactivator 3 (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP) Length = 1424 Score = 30.0 bits (66), Expect = 2.8 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 3/92 (3%) Query: 395 EKLRPL-SGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQ-QL 452 E L PL S S +LP D G E + + Y+ E EL+ NL + + Sbjct: 6 ENLDPLASDSRKRKLPCDTPGQGLTCSGEKRR-REQESKYIEELAELISANLSDIDNFNV 64 Query: 453 KPYTMDLMEQVALRVQELQEQLRVVGEDTKAQ 484 KP ++++ ++++++EQ + + D Q Sbjct: 65 KPDKCAILKETVRQIRQIKEQGKTISNDDDVQ 96
>gi|20139068|sp|Q96PB7|NOE3_HUMAN Noelin 3 precursor (Olfactomedin 3) (Optimedin) (UNQ1924/PRO4399) Length = 478 Score = 30.0 bits (66), Expect = 2.8 Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 8/143 (5%) Query: 67 KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADE--LKAKIDQNVEELKGRLTP 124 K R+ QL ++ +Q +E + Q L+ LKAK Q ++ K +T Sbjct: 82 KSRQLRQLLEKVQNMSQSIEVLNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTK 141 Query: 125 YADEFKVKIDQTVEELRRSLAPYAQDTQ--EKLNHQLEGLTFQMKKNAEELKARISASAE 182 + E K K+D+ + L L Y D + + ++ L+ + EE+ A E Sbjct: 142 HFQELKEKMDELL-PLIPVLEQYKTDAKLITQFKEEIRNLSAVLTGIQEEIGA---YDYE 197 Query: 183 ELRQRLAPLAEDVRGNLRGNTEG 205 EL QR+ L +R ++ T G Sbjct: 198 ELHQRVLSLETRLRDCMKKLTCG 220
>gi|51338744|sp|O75426|FX24_HUMAN F-box only protein 24 Length = 580 Score = 30.0 bits (66), Expect = 2.8 Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 2/39 (5%) Query: 407 RLPQDPVGMRRQLQEELEEVKA--RLQPYMAEAHELVGW 443 R PQDP GM + +E L ++ + LQ + E+VGW Sbjct: 507 RAPQDPGGMAQACEEYLSQIHSCQTLQDRTEKMKEIVGW 545
>gi|123408|sp|P28069|PIT1_HUMAN Pituitary-specific positive transcription factor 1 (Pit-1) (Growth hormone factor 1) (GHF-1) Length = 291 Score = 30.0 bits (66), Expect = 2.8 Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 9/151 (5%) Query: 93 ADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKV---KIDQTVEELRRSLAP-YA 148 A + LR + ++ ID + E++ L +A+EFKV K+ T + +LA + Sbjct: 104 AADFKQELRRKSKLVEEPIDMDSPEIR-ELEKFANEFKVRRIKLGYTQTNVGEALAAVHG 162 Query: 149 QDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQK 208 + + + E L K NA +LKA +S EE Q A E V N R Sbjct: 163 SEFSQTTICRFENLQLSFK-NACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTI 221 Query: 209 SLA---ELGGHLDQQVEEFRRRVEPYGENFN 236 S+A L H +Q + + + E N Sbjct: 222 SIAAKDALERHFGEQNKPSSQEIMRMAEELN 252
>gi|12643528|sp|O00311|CDC7_HUMAN Cell division cycle 7-related protein kinase (CDC7-related kinase) (HsCdc7) (huCdc7) Length = 574 Score = 30.0 bits (66), Expect = 2.8 Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 523 SGIGRHVQELHRSVAPHAPASPA-RLSRCVQVLSRKLTLKAKALHARIQQN 572 S G +H S++ +PA + S+ V VLSRKL K KA+ ++ + Sbjct: 285 SVFGERNFNIHSSISHESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNS 335
>gi|12644130|sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) Length = 2871 Score = 30.0 bits (66), Expect = 2.8 Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 13/148 (8%) Query: 314 SATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPAGSVRDDLGTKEMMEASSLTAWISV 373 S ++ K + +QT+ + RVE+ QQ+ A S R E+ + + + SV Sbjct: 1404 SLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV 1463 Query: 374 PFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE---LEEVKARL 430 + ++L D+ + + + NK +E+L+ L E R+ L++E L+ V+ L Sbjct: 1464 RYKQSLDDA-AKTIQDKNKEIERLKQLIDKE--------TNDRKCLEDENARLQRVQYDL 1514 Query: 431 QPYMAEAHELVGWNLEGLRQQLKPYTMD 458 Q + A E + L+ Q+L +D Sbjct: 1515 QKANSSATETIN-KLKVQEQELTRLRID 1541
>gi|6225268|sp|O60610|DIAP1_HUMAN Diaphanous protein homolog 1 (Diaphanous-related formin 1) (DRF1) Length = 1248 Score = 30.0 bits (66), Expect = 2.8 Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 9/117 (7%) Query: 170 AEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQ-----QVEEF 224 AEEL R+ +E +R L + +D+R + +Q ++ + G D ++++ Sbjct: 316 AEELDFRVHIRSELMRLGLHQVLQDLR-EIENEDMRVQLNVFDEQGEEDSYDLKGRLDDI 374 Query: 225 RRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKKFWYELEDTC 281 R ++ + E F L + K PH + HL + D + +Y+L + C Sbjct: 375 RMEMDDFNEVFQILLNTVKDS---KAEPHFLSILQHLLLVRNDYEARPQYYKLIEEC 428
>gi|32469788|sp|Q9NYA3|GOA6_HUMAN Golgi autoantigen, golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein) Length = 693 Score = 30.0 bits (66), Expect = 2.8 Identities = 31/119 (26%), Positives = 57/119 (47%), Gaps = 12/119 (10%) Query: 376 SRTLKDSLEQDLNNMNKFLEKLRPLSG--SEAPRLPQDPV--------GMRRQLQEELEE 425 +RTLK+ ++D++ + + L L +E P L V + L++E+E Sbjct: 254 ARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEG 313 Query: 426 VKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQ 484 ++ +LQ E ++ + + +Q+L+ L EQ A RV+E QE+L E + Q Sbjct: 314 LEGKLQS-QVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVRE-QERLCEQNERLREQ 370
>gi|48474671|sp|Q9NSB2|K2H4_HUMAN Keratin, type II cuticular HB4 (Hair keratin, type II HB4) Length = 600 Score = 30.0 bits (66), Expect = 2.8 Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 13/135 (9%) Query: 86 ERVLRENADSLQASLRPHAD-------ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE 138 E V R NA++ +L+ D +L+A +D +E+ T Y +E ++ Sbjct: 256 EVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQL----LQS 311 Query: 139 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGN 198 + + D LN L+G+ ++K EE+ R A AE Q + G Sbjct: 312 HISETSVIVKMDNSRDLN--LDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQ 369 Query: 199 LRGNTEGLQKSLAEL 213 N ++ + EL Sbjct: 370 HCDNLRNIRNEINEL 384
>gi|42558941|sp|O75145|LPA3_HUMAN Liprin-alpha 3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 3) (PTPRF-interacting protein alpha 3) Length = 1194 Score = 29.6 bits (65), Expect = 3.6 Identities = 49/186 (26%), Positives = 78/186 (41%), Gaps = 32/186 (17%) Query: 401 SGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLM 460 +G E RL + R +L E L E + L EL G + L++QL ++ L Sbjct: 24 AGGELERLMVTMLTERERLLETLREAQDGLATAQLRLREL-GHEKDSLQRQL---SIALP 79 Query: 461 EQVALRVQEL---QEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPY 517 ++ A +EL +EQL + E+ A+L + LL+ L Sbjct: 80 QEFAALTKELNLCREQL-LEREEEIAELKAERNNTRLLLEHL------------------ 120 Query: 518 AESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLS--RKLTLKAKALHARIQQNLDQ 575 E LVS RH + L +V SP +S V+VL + L KAL ++++ L Sbjct: 121 -ECLVS---RHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRM 176 Query: 576 LREELS 581 E ++ Sbjct: 177 ALERVA 182
>gi|586120|sp|Q07283|TRHY_HUMAN Trichohyalin Length = 1898 Score = 29.6 bits (65), Expect = 3.6 Identities = 45/202 (22%), Positives = 80/202 (39%), Gaps = 27/202 (13%) Query: 53 ELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKID 112 E QQL++ +E +QLRR Q +ER RE ++L+ + + Sbjct: 1650 EEEQQLRRQERERKFLQEEQQLRR------QELERKFREE------------EQLRQETE 1691 Query: 113 QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE 172 Q + R +E +++ ++ ++LRR +E+L E + +++ + Sbjct: 1692 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQGREEQQLRSQESDRK 1751 Query: 173 LKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPY- 231 + E Q+L P D G R E LQ L E L Q+ + R E + Sbjct: 1752 FREEEQLRQEREEQQLRPQQRD--GKYRWEEEQLQ--LEEQEQRLRQERDRQYRAEEQFA 1807 Query: 232 ----GENFNKALVQQMEQLRQK 249 + L Q+ EQ R++ Sbjct: 1808 TQEKSRREEQELWQEEEQKRRQ 1829
Score = 29.3 bits (64), Expect = 4.8 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 7/99 (7%) Query: 67 KGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQ---NVEELKGRLT 123 +GRE +QLR Q + R E LR+ + Q LRP + K + ++ +EE + RL Sbjct: 1736 QGREEQQLRSQESDRKFREEEQLRQEREEQQ--LRPQQRDGKYRWEEEQLQLEEQEQRLR 1793 Query: 124 PYADEFKVKIDQ--TVEELRRSLAPYAQDTQEKLNHQLE 160 D +Q T E+ RR Q+ ++K + E Sbjct: 1794 QERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE 1832
Score = 28.5 bits (62), Expect = 8.1 Identities = 50/246 (20%), Positives = 98/246 (39%), Gaps = 8/246 (3%) Query: 38 LSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLRENADSLQ 97 L ++ + LQ+ E ++L++ + +E E+ R+ Q E++LRE + + Sbjct: 912 LQEQLRKEQQLLQEEE--EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 969 Query: 98 ASLRPHADELKAKIDQNVEELKG-RLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLN 156 R K+ Q E+L G + + K + EEL++ ++ +EK Sbjct: 970 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1029 Query: 157 HQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGH 216 Q ++ K ++ + ++ E ++RL R E Q E Sbjct: 1030 RQEWERQYRKKDELQQEEEQLLREERE-KRRLQERERQYREEEELQQEEEQLLGEERETR 1088 Query: 217 LDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDL----RDKK 272 Q++E R+ E + + L ++ E+ R++ E L E+ L R+K+ Sbjct: 1089 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1148 Query: 273 FWYELE 278 ELE Sbjct: 1149 RRQELE 1154
>gi|132517|sp|P14373|RFP_HUMAN Zinc-finger protein RFP (Ret finger protein) (Tripartite motif protein 27) (RING finger protein 76) Length = 513 Score = 29.6 bits (65), Expect = 3.6 Identities = 42/196 (21%), Positives = 76/196 (38%), Gaps = 21/196 (10%) Query: 52 SELTQQLKKTGPSGIKGREA--EQLRRQLTPYAQRMERVL-------RENADSLQASLRP 102 ++L +QL+ PSG G E+ R L Y + + + RE+ L Sbjct: 75 TQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGHSVLPLEE 134 Query: 103 HADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGL 162 + K +I ++ LK + K + E+ R L Q +EK+ + E L Sbjct: 135 AVEGFKEQIQNQLDHLKR-----VKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQL 189 Query: 163 TFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVE 222 +K++ L AR+ EEL + N L +A+L ++Q + Sbjct: 190 YHSLKEHEYRLLARL----EELDLAIYNSINGAITQFSCNISHLSSLIAQLE---EKQQQ 242 Query: 223 EFRRRVEPYGENFNKA 238 R ++ G+ ++A Sbjct: 243 PTRELLQDIGDTLSRA 258
>gi|48474260|sp|O43790|KRHB6_HUMAN Keratin, type II cuticular HB6 (Hair keratin, type II HB6) (ghHb6) Length = 486 Score = 29.6 bits (65), Expect = 3.6 Identities = 40/176 (22%), Positives = 67/176 (38%), Gaps = 33/176 (18%) Query: 74 LRRQLTPYAQRMERVLRENADSLQASLRPHAD------------ELKAKIDQNVEELKGR 121 L ++ P AQ +++ +E SL + D E K + QN E + Sbjct: 91 LNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSN 150 Query: 122 LTPYADEFKVKIDQTVEELRRSLAPYAQDT---QEKLNHQLEGLTFQMKKNAEELKARIS 178 L P + + +E LRR D+ +LNH E L KK EE+ R + Sbjct: 151 LEPLFEGY-------IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRAT 203 Query: 179 ASAEELRQRLAPLAEDV------RGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRV 228 A E L +DV + +L N E L + + L ++++ + + Sbjct: 204 AENE-----FVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHI 254
>gi|47606192|sp|Q8WV44|TM41_HUMAN Tripartite motif protein 41 Length = 630 Score = 29.6 bits (65), Expect = 3.6 Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 26/141 (18%) Query: 122 LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA 181 L E+K K+ + VE LR+ L + +K+ + E ++K ++K+ ++A A Sbjct: 263 LEEVVQEYKAKLQEHVEPLRKHL-----EAVQKMKAKEERRVTELK---SQMKSELAAVA 314 Query: 182 EELRQRLAPLAEDVRGNLR----------GNTEGLQKSLAELGGHLDQQVEEFRRRVEPY 231 E + LAE+ G R G LAE L + + E + R + Sbjct: 315 SEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQERSQQG 374 Query: 232 G--------ENFNKALVQQME 244 G E FN+ Q++ Sbjct: 375 GLRLLQDIKETFNRCEEVQLQ 395
>gi|14916980|sp|P26232|CTN2_HUMAN Alpha-2 catenin (Alpha-catenin related protein) (Alpha N-catenin) Length = 953 Score = 29.6 bits (65), Expect = 3.6 Identities = 34/167 (20%), Positives = 70/167 (41%), Gaps = 9/167 (5%) Query: 416 RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR 475 R ++ E V+ LQ ++E N G +++ P + + +++ + ++L+ QLR Sbjct: 328 RERIVAECNAVRQALQDLLSEY-----MNNTGRKEKGDPLNIAI-DKMTKKTRDLRRQLR 381 Query: 476 -VVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLV--SGIGRHVQEL 532 V + L L++ +S + ++F +A LV + + + Sbjct: 382 KAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNN 441 Query: 533 HRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREE 579 V A+ S C QV++ LTL A+ Q N+D +++ Sbjct: 442 EEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQ 488
>gi|37999860|sp|O14686|MLL2_HUMAN Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein) Length = 5262 Score = 29.6 bits (65), Expect = 3.6 Identities = 24/111 (21%), Positives = 53/111 (47%), Gaps = 8/111 (7%) Query: 400 LSGSEAPRLPQDPVGMRRQLQ-----EELEEVKARLQPYMAEAHELVGWNLEGLRQQ--- 451 +S S P+L P+G +QLQ ++ ++++ + Q + + +L L+ +QQ Sbjct: 3606 MSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQL 3665 Query: 452 LKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSR 502 + L +Q Q+ Q+Q + + + Q +G ++++ LL Q + Sbjct: 3666 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3716
>gi|23396625|sp|Q9NQT8|K13B_HUMAN Kinesin-like protein KIF13B (Kinesin-like protein GAKIN) Length = 1826 Score = 29.6 bits (65), Expect = 3.6 Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 19/157 (12%) Query: 33 DYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR-- 90 D + N+ ++ E ++S L +Q + E EQLRR+L+P Q + R Sbjct: 605 DPMQSILNSLEQQHEEEKRSALERQRL------MYEHELEQLRRRLSPEKQNCRSMDRFS 658 Query: 91 ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQD 150 ++ S Q LR A+E +A ++ ++ L+ ++ VK + V E + Sbjct: 659 FHSPSAQQRLRQWAEEREATLNNSLMRLREQI--------VKANLLVREANYIAEELDKR 710 Query: 151 TQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQR 187 T+ K+ Q+ + + L +S A ++R++ Sbjct: 711 TEYKVTLQIPASSLDANRKRGSL---LSEPAIQVRRK 744
>gi|51701437|sp|Q8TF61|FBX41_HUMAN F-box only protein 41 Length = 875 Score = 29.6 bits (65), Expect = 3.6 Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 14/90 (15%) Query: 112 DQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE 171 D EE RL A E K+++D+ +E L +++ ++K+ Q+ L ++++ A Sbjct: 195 DVAYEEGLARLKIRALE-KLEVDRRLERL-------SEEVEQKIAGQVGRLQAELERKAA 246 Query: 172 ELK------ARISASAEELRQRLAPLAEDV 195 EL+ AR+ EEL +R + L+ V Sbjct: 247 ELETARQESARLGREKEELEERASELSRQV 276
>gi|32129445|sp|Q96SN8|C5P2_HUMAN CDK5 regulatory subunit associated protein 2 (CDK5 activator-binding protein C48) Length = 1893 Score = 29.6 bits (65), Expect = 3.6 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 20/98 (20%) Query: 152 QEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLA 211 +E++ + G T + K ELK + + EL++R L + + +SLA Sbjct: 85 EERMQQEFHGPTEHIYKTNIELKVEVESLKRELQEREQLLIKASKA---------VESLA 135 Query: 212 ELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQK 249 E GG Q+V+E R+ VQQ+E L K Sbjct: 136 EAGGSEIQRVKEDARK-----------KVQQVEDLLTK 162
>gi|47606049|sp|Q9H5N1|RAP2_HUMAN Rab GTPase binding effector protein 2 (Rabaptin-5beta) Length = 569 Score = 29.6 bits (65), Expect = 3.6 Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 7/129 (5%) Query: 85 MERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL 144 ++R +E SLQA L+ +A+I +E + + +E + ++ + + L R+ Sbjct: 75 VQRQCQEEVASLQAILKDSISSYEAQITALKQERQQQQQD-CEEKERELGRLKQLLSRAY 133 Query: 145 APYAQDTQEKLNHQ----LEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLR 200 + + Q + H+ L + M+K EELKA++ AEEL Q + +L Sbjct: 134 PLDSLEKQMEKAHEDSEKLREIVLPMEKEIEELKAKL-LRAEELIQEIQRRPRHA-PSLH 191 Query: 201 GNTEGLQKS 209 G+TE L S Sbjct: 192 GSTELLPLS 200
>gi|1171955|sp|P42338|P11B_HUMAN Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, beta isoform (PI3-kinase p110 subunit beta) (PtdIns-3-kinase p110) (PI3K) (PI3Kbeta) Length = 1070 Score = 29.3 bits (64), Expect = 4.8 Identities = 38/141 (26%), Positives = 58/141 (41%), Gaps = 24/141 (17%) Query: 208 KSLAELGGHLDQQVEEFRRRVEPYGENFNKALV--QQMEQLRQKLGPHAGDVEGHLSFLE 265 K L E D +V EFRR++ + E +LV M+ L+Q P H + Sbjct: 132 KGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPE------HEPSIP 185 Query: 266 KDLRDKKFWYEL-----EDTCPVGGLPPPVFSEQVMASMAAVLTWALALLSAFS--ATQA 318 ++L DK + +L + C VFS QV +M + LA+ + + Sbjct: 186 ENLEDKLYGGKLIVAVHFENC------QDVFSFQVSPNMNPIKVNELAIQKRLTIHGKED 239 Query: 319 RKGFWDYFSQTSGDKGRVEQI 339 +DY Q S GRVE + Sbjct: 240 EVSPYDYVLQVS---GRVEYV 257
>gi|1346344|sp|P02538|K2C6A_HUMAN Keratin, type II cytoskeletal 6A (Cytokeratin 6A) (CK 6A) (K6a keratin) Length = 564 Score = 29.3 bits (64), Expect = 4.8 Identities = 32/139 (23%), Positives = 57/139 (41%), Gaps = 15/139 (10%) Query: 113 QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE 172 Q V + LTP ++ID T++ +R + K ++ + F ++N + Sbjct: 136 QEVTVNQSLLTP----LNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQN-KV 190 Query: 173 LKARISASAEE----LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL---DQQVEEFR 225 L+ + + E+ +RQ L PL E NLR + + L L VE+F+ Sbjct: 191 LETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFK 250 Query: 226 RRVEPYGENFNKALVQQME 244 + Y + NK + E Sbjct: 251 NK---YEDEINKRTAAENE 266
>gi|23503075|sp|P08779|K1CP_HUMAN Keratin, type I cytoskeletal 16 (Cytokeratin 16) (K16) (CK 16) Length = 473 Score = 29.3 bits (64), Expect = 4.8 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 12/128 (9%) Query: 26 QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRM 85 ++ M D + Q++ + E S+ T++L K S + R ++T + Sbjct: 284 RILNEMRDQYEQMAEKNRRDAETWFLSK-TEELNKEVASN--SELVQSSRSEVT----EL 336 Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 RVL+ LQ+ L +KA ++ ++EE KGR + + I E+L + Sbjct: 337 RRVLQGLEIELQSQL-----SMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRC 391 Query: 146 PYAQDTQE 153 Q +QE Sbjct: 392 EMEQQSQE 399
>gi|29427676|sp|Q16891|IMMT_HUMAN Mitochondrial inner membrane protein (Mitofilin) (p87/89) Length = 758 Score = 29.3 bits (64), Expect = 4.8 Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%) Query: 44 EAVEHLQKSELTQQLKKTGP--SGIKGREAEQLRRQLTPYAQRMERVLRENADSLQASLR 101 +A+EH + +Q +K ++ QLRRQ + + VLR L++ Sbjct: 451 KALEHHRSEIQAEQDRKIEEVRDAMENEMRTQLRRQAAAHTDHLRDVLRVQEQELKSEFE 510 Query: 102 PHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELR---RSLAPYAQDTQE-KLNH 157 + E K+ + + + D F + I+ LR +++ +A +E + H Sbjct: 511 QNLSE---KLSEQELQFRRLSQEQVDNFTLDINTAYARLRGIEQAVQSHAVAEEEARKAH 567 Query: 158 QL----EGLTFQMKKNAEELKARISASAEE 183 QL E L + MK ++ E SA E Sbjct: 568 QLWLSVEALKYSMKTSSAETPTIPLGSAVE 597
>gi|46397468|sp|Q14533|K2H1_HUMAN Keratin, type II cuticular HB1 (Hair keratin, type II HB1) (ghHKb1) (ghHb1) (MLN 137) Length = 505 Score = 29.3 bits (64), Expect = 4.8 Identities = 39/154 (25%), Positives = 58/154 (37%), Gaps = 33/154 (21%) Query: 74 LRRQLTPYAQRMERVLRENADSLQASLRPHAD------------ELKAKIDQNVEELKGR 121 L ++ P AQ +++ +E SL + D E K + QN E + Sbjct: 91 LNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSN 150 Query: 122 LTPYADEFKVKIDQTVEELRRSLAPYAQDT---QEKLNHQLEGLTFQMKKNAEELKARIS 178 L P + + +E LRR D+ +LNH E L KK EE+ R + Sbjct: 151 LEPLFEGY-------IETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRAT 203 Query: 179 ASAEELRQRLAPLAEDV------RGNLRGNTEGL 206 A E L +DV + +L N E L Sbjct: 204 AENE-----FVALKKDVDCAYLRKSDLEANVEAL 232
>gi|42558969|sp|Q13136|LPA1_HUMAN Liprin-alpha 1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha 1) (PTPRF-interacting protein alpha 1) (LAR-interacting protein 1) (LIP.1) Length = 1202 Score = 29.3 bits (64), Expect = 4.8 Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 29/212 (13%) Query: 398 RPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTM 457 +P + S +L + R +L + L E + L + HE VG + L++QL Sbjct: 29 QPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHE-VGHERDSLQRQLNTALP 87 Query: 458 DLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPY 517 + + +EQL + E+ A+L + LL+ L Sbjct: 88 QEFAALTKELNVCREQL-LEREEEIAELKAERNNTRLLLEHL------------------ 128 Query: 518 AESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLS--RKLTLKAKALHARIQQNLDQ 575 E LVS RH + L +V SPA +S V+VL + L KAL +++ ++ Sbjct: 129 -ECLVS---RHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVR---ER 181 Query: 576 LREELSRAFXXXXXXXXXXPDPQMLSEEVRQR 607 LR L R + +L E+ Q+ Sbjct: 182 LRVALERCSLLEEELGATHKELMILKEQNNQK 213
>gi|37999758|sp|Q96PP9|GBP4_HUMAN Guanylate binding protein 4 Length = 640 Score = 29.3 bits (64), Expect = 4.8 Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 11/106 (10%) Query: 43 KEAVEHLQKSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMER----VLRENADSLQA 98 KEA E ++ EL ++ +K ++ +E + + ++MER +LRE+ L+ Sbjct: 510 KEAAE--KEQELLREKQKEQQQMMEAQE-RSFQENIAQLKKKMERERENLLREHERLLKH 566 Query: 99 SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSL 144 L+ + LK + + E+L + ++ K KI+ T E R L Sbjct: 567 KLKVQEEMLKEEFQKKSEQLNKEI----NQLKEKIESTKNEQLRLL 608
>gi|20981708|sp|P47972|NPTX2_HUMAN Neuronal pentraxin-2 precursor (NP2) (Neuronal pentraxin II) (NP-II) Length = 431 Score = 28.9 bits (63), Expect = 6.2 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Query: 408 LPQDPVGMRRQLQEELEEVKARLQPYMAEAHELV-GWNLEG-LRQQLKPYTMDLMEQVAL 465 LP+DP + QL L+ +K RL+ + V L G R+ L+ +L Q+ Sbjct: 116 LPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAGLPGDFREVLQQRLGELERQLLR 175 Query: 466 RVQELQEQLRVVGEDTKAQLLGGVDEAWALLQ 497 +V EL+++ ++ +T A ALLQ Sbjct: 176 KVAELEDEKSLLHNETSAHRQKTESTLNALLQ 207
>gi|18202738|sp|Q9BXS5|AP1M1_HUMAN Adaptor-related protein complex 1, mu 1 subunit (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat associated protein AP47) (AP-mu chain family member mu1A) Length = 423 Score = 28.9 bits (63), Expect = 6.2 Identities = 35/141 (24%), Positives = 59/141 (41%), Gaps = 8/141 (5%) Query: 375 FSRTLKDSLEQDL-NNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPY 433 FS K+ E+ + +N E L L P+ + ++ + +E +++ Sbjct: 91 FSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKI-LQEYITQEGHKLETGAPRP 149 Query: 434 MAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLR--VVGEDTKAQLLGGVDE 491 A V W EG++ + +D++E V L V LR +VG L G+ E Sbjct: 150 PATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPE 209 Query: 492 AWALLQGLQSRVV-HHTGRFK 511 L GL +V+ +TGR K Sbjct: 210 ---LRLGLNDKVLFDNTGRGK 227
>gi|6136547|sp|O60299|Y552_HUMAN Hypothetical protein KIAA0552 Length = 673 Score = 28.9 bits (63), Expect = 6.2 Identities = 19/87 (21%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 109 AKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQM-- 166 A + +++E+ + + +E + ++ + ELR+ + Q + +GL Q+ Sbjct: 336 AALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLR 395 Query: 167 ----KKNAEELKARISASAEELRQRLA 189 KK +E AR+ EEL ++A Sbjct: 396 LQQDKKQLQEEAARLMRQREELEDKVA 422
>gi|48475013|sp|Q9UMX0|UBQ1_HUMAN Ubiquilin 1 (Protein linking IAP with cytoskeleton-1) (PLIC-1) (hPLIC-1) Length = 589 Score = 28.9 bits (63), Expect = 6.2 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEEL 118 EQ+R+QL + Q+M+ N D+L A P A + +I Q ++ L Sbjct: 432 EQMRQQLPTFLQQMQ-----NPDTLSAMSNPRAMQALLQIQQGLQTL 473
>gi|46397817|sp|P12814|AAC1_HUMAN Alpha-actinin 1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin 1) (F-actin cross linking protein) Length = 892 Score = 28.9 bits (63), Expect = 6.2 Identities = 47/235 (20%), Positives = 89/235 (37%), Gaps = 38/235 (16%) Query: 32 WDYFSQLSNNAKEAVEHLQK-SELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR 90 WD L+ +EA+E +K E QL + ++ P+ ME + Sbjct: 483 WDNLGALTQKRREALERTEKLLETIDQLYL------------EYAKRAAPFNNWMEGAM- 529 Query: 91 ENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKV----------KIDQTVEEL 140 + LQ + H E + E+ K L P AD+ ++ KI QT Sbjct: 530 ---EDLQDTFIVHTIEEIQGLTTAHEQFKATL-PDADKERLAILGIHNEVSKIVQTYHVN 585 Query: 141 RRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA--EELRQRLAPLAEDVRGN 198 PY T +++N + + + + + + L + E LR++ A + Sbjct: 586 MAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPW 645 Query: 199 LRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPH 253 ++ E + + E+ G L+ Q+ R+ + K++V ++ Q G H Sbjct: 646 IQTKMEEIGRISIEMHGTLEDQLSHLRQ--------YEKSIVNYKPKIDQLEGDH 692
>gi|34925430|sp|Q9HCN4|XAB1_HUMAN XPA-binding protein 1 (HUSSY-23) Length = 374 Score = 28.9 bits (63), Expect = 6.2 Identities = 39/171 (22%), Positives = 70/171 (40%), Gaps = 23/171 (13%) Query: 77 QLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQT 136 Q T Y + R + D +SLR + A + ++EL ++T A+E++ + Sbjct: 215 QETTYVSNLTRSMSLVLDEFYSSLRVVG--VSAVLGTGLDELFVQVTSAAEEYEREYRPE 272 Query: 137 VEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAED-- 194 E L++SLA A+ Q++ QLE L M ++ A + L+P+ Sbjct: 273 YERLKKSLA-NAESQQQR--EQLERLRKDM--------GSVALDAGTAKDSLSPVLHPSD 321 Query: 195 ---VRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQ 242 RG L E ++ + ++ E EP +NF + + Q Sbjct: 322 LILTRGTLDEEDEEADSDTDDIDHRVTEESHE-----EPAFQNFMQESMAQ 367
>gi|125953|sp|P20700|LAM1_HUMAN Lamin B1 Length = 586 Score = 28.9 bits (63), Expect = 6.2 Identities = 29/164 (17%), Positives = 67/164 (40%), Gaps = 7/164 (4%) Query: 72 EQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKV 131 E L + + Y + + R++ L E + K+ Q + E++ + +K Sbjct: 203 EDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEYKLAQALHEMREQHDAQVRLYKE 262 Query: 132 KIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELR------ 185 +++QT + ++ +N E L + + E L +++S +E R Sbjct: 263 ELEQTYHAKLENARLSSEMNTSTVNSAREEL-MESRMRIESLSSQLSNLQKESRACLERI 321 Query: 186 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVE 229 Q L L + N R ++ +AE+ + QQ+ ++ + ++ Sbjct: 322 QELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDYEQLLD 365
>gi|56417894|sp|Q8NE71|ABF1_HUMAN ATP-binding cassette, sub-family F, member 1 (ATP-binding cassette 50) (TNF-alpha stimulated ABC protein) Length = 845 Score = 28.9 bits (63), Expect = 6.2 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 5/79 (6%) Query: 86 ERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLA 145 + V+ + ++QA LR AD + K+ + L+G+L D ++++ EELR A Sbjct: 367 QEVVADETPAVQAVLR--ADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR---A 421 Query: 146 PYAQDTQEKLNHQLEGLTF 164 A + K L GL F Sbjct: 422 TGAAAAEAKARRILAGLGF 440
>gi|2497603|sp|Q13753|LMG2_HUMAN Laminin gamma-2 chain precursor (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit) Length = 1193 Score = 28.9 bits (63), Expect = 6.2 Identities = 43/171 (25%), Positives = 72/171 (42%), Gaps = 25/171 (14%) Query: 46 VEHLQKSE-LTQQLKKTGPSG-IKGREAEQLRRQLTPYAQRMERV------------LRE 91 VE L+K++ L QQL + I+ + Q +L R++ V +++ Sbjct: 817 VEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQ 876 Query: 92 NADSLQASLRPHADELK--AKIDQNVEELKGRLTPYADEFKVKIDQTVE--ELRRSLAPY 147 ADSL + H DE K K N +E +L + K DQ + L +S A Sbjct: 877 KADSLSTLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQE 936 Query: 148 AQDTQEKLNHQLEGLTFQMKKNAEELKARI---SASAEELRQRLAPLAEDV 195 A +++E + KN E ++ A AEE +RL+ +++ V Sbjct: 937 ALSMGNATFYEVESIL----KNLREFDLQVDNRKAEAEEAMKRLSYISQKV 983
>gi|20455507|sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1 / hnRNP C2) Length = 306 Score = 28.9 bits (63), Expect = 6.2 Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 7/121 (5%) Query: 66 IKGREAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPY 125 +KG + + ++++LT Q+++ +L EN + ++ A E+K + EE + + Sbjct: 188 LKGDDLQAIKKELTQIKQKVDSLL-ENLEKMEKEQSKQAVEMK---NDKSEEEQSSSSVK 243 Query: 126 ADEFKVKIDQ---TVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAE 182 DE VK++ + D +++ + QLE + K+ E R SA+ E Sbjct: 244 KDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGE 303 Query: 183 E 183 + Sbjct: 304 D 304
>gi|2506774|sp|P05787|K2C8_HUMAN Keratin, type II cytoskeletal 8 (Cytokeratin 8) (K8) (CK 8) Length = 483 Score = 28.9 bits (63), Expect = 6.2 Identities = 24/127 (18%), Positives = 53/127 (41%), Gaps = 9/127 (7%) Query: 51 KSELTQQLKKTGPSGIKGREAEQLRRQLTPYAQRMERVLR-----ENADSLQASLRPHAD 105 ++E Q+K + G+ + LRR T ++ + R E +ASL Sbjct: 277 EAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIA 336 Query: 106 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ 165 + + + + +++ +L+ E + + + +++ R L Y + KL +E T++ Sbjct: 337 DAEQRGELAIKDANAKLS----ELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYR 392 Query: 166 MKKNAEE 172 EE Sbjct: 393 KLLEGEE 399
>gi|55977767|sp|P08670|VIME_HUMAN Vimentin Length = 466 Score = 28.5 bits (62), Expect = 8.1 Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 13/115 (11%) Query: 567 ARIQQNLDQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRA- 625 AR++ D L E++ R + + EE LQ+FRQD + A+ R Sbjct: 169 ARVEVERDNLAEDIMRL-------REKLQEEMLQREEAENTLQSFRQD--VDNASLARLD 219 Query: 626 IDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHD 680 ++++ E +Q+++A H E Q+ + +Q +D D+T +L D Sbjct: 220 LERKVESLQEEIAFLKKLHE---EEIQELQAQIQEQHVQIDVDVSKPDLTAALRD 271
>gi|25014073|sp|O43615|TIM44_HUMAN Import inner membrane translocase subunit TIM44, mitochondrial precursor Length = 452 Score = 28.5 bits (62), Expect = 8.1 Identities = 42/196 (21%), Positives = 77/196 (39%), Gaps = 30/196 (15%) Query: 26 QVATVMWDYFSQLSNNAKEAVEHLQKSELTQQL-----------KKTGPSGIKGREAEQL 74 + + V+ +L+ KE++ + KS+L +++ K++ S KG E Sbjct: 113 RTSEVLRKKLGELTGTVKESLHEVSKSDLGRKIKEGVEEAAKTAKQSAESVSKGGEKLGR 172 Query: 75 RRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFK-VKI 133 +Q +E V +E DS+ P+ + + L+ R D+FK K+ Sbjct: 173 TAAFRALSQGVESVKKEIDDSVLGQTGPY---------RRPQRLRKRTEFAGDKFKEEKV 223 Query: 134 DQTVEE-----LRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRL 188 + EE L + Y Q K N+ + F+MK +E ++ L ++ Sbjct: 224 FEPNEEALGVVLHKDSKWYQQWKDFKENNVVFNRFFEMKMKYDESDNAFIRASRALTDKV 283 Query: 189 APLAEDVRGNLRGNTE 204 D+ G L TE Sbjct: 284 T----DLLGGLFSKTE 295
>gi|1710877|sp|P48594|SCCA2_HUMAN Squamous cell carcinoma antigen 2 (SCCA-2) (Leupin) Length = 390 Score = 28.5 bits (62), Expect = 8.1 Identities = 31/149 (20%), Positives = 59/149 (39%), Gaps = 15/149 (10%) Query: 134 DQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKK--NAEELKARISASAEELRQRLAPL 191 DQ E A Y D ++HQ + L + K +A ELK E+ Q L Sbjct: 60 DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119 Query: 192 AEDVRGNLRGNTEGL------QKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 245 + ++ + + E ++S ++ ++ Q E + + P G N + + Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179 Query: 246 LRQKLGPHAGDVEGHLSFLEKDLRDKKFW 274 + K G E F +++ +++KFW Sbjct: 180 IYFK-----GQWEN--KFKKENTKEEKFW 201
>gi|50401600|sp|Q8N0X7|SP20_HUMAN Spartin (Trans-activated by hepatitis C virus core protein 1) Length = 666 Score = 28.5 bits (62), Expect = 8.1 Identities = 35/164 (21%), Positives = 64/164 (39%), Gaps = 21/164 (12%) Query: 72 EQLRRQLTPYAQRME--RVLRENADSLQASLRPHADELKAKIDQNVEEL----------- 118 E L RQ++ + R EN + RP +D+LK +V++L Sbjct: 324 EDLLRQMSDLRLQANWNRAEEENEFQIPGRTRPSSDQLKEASGTDVKQLDQGNKDVRHKG 383 Query: 119 -KGRLTPYADEFKVKIDQTV------EELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAE 171 +G+ +V + V EE + L +++ + +++ + K AE Sbjct: 384 KRGKRAKDTSSEEVNLSHIVPCEPVPEEKPKELPEWSEKVAHNILSGASWVSWGLVKGAE 443 Query: 172 ELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGG 215 I A +LR+R+ P + V + T+GL + GG Sbjct: 444 ITGKAIQKGASKLRERIQPEEKPVEVS-PAVTKGLYIAKQATGG 486
>gi|37999907|sp|Q9P275|UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (Ubiquitin thiolesterase 36) (Ubiquitin-specific processing protease 36) (Deubiquitinating enzyme 36) Length = 1121 Score = 28.5 bits (62), Expect = 8.1 Identities = 27/85 (31%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Query: 348 PAGSVRDDLGTKEMMEASSLTAWISVPFSRTLKDSLEQDLNNMNKFLEKLRPLSGSEAPR 407 P R D GT M+ T I VP SR + L + N + P SGS +P+ Sbjct: 465 PLTGKRQDSGT---MKKPHTTEEIGVPISR---NGSTLGLKSQNGCIPPKLP-SGSPSPK 517 Query: 408 LPQDPVGMRRQLQEELEEVKARLQP 432 L Q P M L + ++VK P Sbjct: 518 LSQTPTHMPTILDDPGKKVKKPAPP 542
>gi|30173225|sp|O95347|SMC2_HUMAN Structural maintenance of chromosome 2-like 1 protein (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) (PRO0324) Length = 1197 Score = 28.5 bits (62), Expect = 8.1 Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 9/113 (7%) Query: 70 EAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADEL---KAKIDQNVEEL-KGRLTPY 125 E E+L+R+ T Y Q++E V E S ++ + A E+ K +++ EE+ K + Sbjct: 825 ELEELKREHTSYKQQLEAV-NEAIKSYESQIEVMAAEVAKNKESVNKAQEEVTKQKEVIT 883 Query: 126 ADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARIS 178 A + +K++ + RS ++L+H + + K+ AE+ A++S Sbjct: 884 AQDTVIKLNMQKWQNTRSKTMILSLKIKELDHHIS----KHKREAEDGAAKVS 932
>gi|6226826|sp|O75330|HMMR_HUMAN Hyaluronan mediated motility receptor (Intracellular hyaluronic acid binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen) Length = 724 Score = 28.5 bits (62), Expect = 8.1 Identities = 21/92 (22%), Positives = 42/92 (45%), Gaps = 5/92 (5%) Query: 83 QRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRR 142 ++ ER + + SL EL + + Q + + + + F+ ++ QT++EL + Sbjct: 328 EQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDK 387 Query: 143 SLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK 174 Q +E+ ++ L + K AEELK Sbjct: 388 -----LQQKEEQAERLVKQLEEEAKSRAEELK 414
>gi|13432173|sp|P02533|K1CN_HUMAN Keratin, type I cytoskeletal 14 (Cytokeratin 14) (K14) (CK 14) Length = 472 Score = 28.5 bits (62), Expect = 8.1 Identities = 25/114 (21%), Positives = 47/114 (41%), Gaps = 13/114 (11%) Query: 52 SELTQQLKKTGPSGIKGRE------AEQLRRQLTPYAQRMER------VLRENADSLQAS 99 +E+ Q +K K E E+L R++ ++ ++ LR +L+ Sbjct: 285 NEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIE 344 Query: 100 LRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQE 153 L+ +KA ++ ++EE KGR + + I E+L + Q QE Sbjct: 345 LQSQLS-MKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
>gi|56757580|sp|P13647|K2C5_HUMAN Keratin, type II cytoskeletal 5 (Cytokeratin 5) (K5) (CK 5) (58 kDa cytokeratin) Length = 590 Score = 28.5 bits (62), Expect = 8.1 Identities = 37/178 (20%), Positives = 71/178 (39%), Gaps = 20/178 (11%) Query: 113 QNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEE 172 Q V + LTP ++ID +++ +R + K ++ + F ++N + Sbjct: 141 QEVTVNQSLLTP----LNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQN-KV 195 Query: 173 LKARISASAEE----LRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHL---DQQVEEFR 225 L + + E+ +RQ L PL E NLR + + L L VE+F+ Sbjct: 196 LDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFK 255 Query: 226 RRVEPYGENFNKALVQQMEQLRQKLGPHAG-----DVEGHLSFLEKDLRDKKFWYELE 278 + Y + NK + E + K A ++E + L ++ K +++ E Sbjct: 256 NK---YEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAE 310
>gi|25009281|sp|Q9P2P6|STR9_HUMAN StAR-related lipid transfer protein 9 (StARD9) (START domain-containing protein 9) Length = 1820 Score = 28.5 bits (62), Expect = 8.1 Identities = 46/183 (25%), Positives = 78/183 (42%), Gaps = 16/183 (8%) Query: 461 EQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRVVHH-------TGRFKEL 513 EQ+ L+V L V E T+A+L G EA ALLQ LQS T +KEL Sbjct: 1315 EQIPLQVGAQNLSLSV--ELTEAKLHHGFGEADALLQVLQSGTGEALAADEPVTSTWKEL 1372 Query: 514 FHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNL 573 + +++ + + L + + +LS + ++ L + L +R ++ L Sbjct: 1373 YARQKKAIETLRRERAERLGNFCRTRSLSPQKQLS---LLPNKDLFIWDLDLPSRRREYL 1429 Query: 574 DQLREELSRAFXXXXXXXXXXPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEV 633 QLR+++ P + E + Q Q ++ ++IA RA DQ E Sbjct: 1430 QQLRKDVVETTRSPESVSRSAHTPSDI-ELMLQDYQQAHEEAKVEIA---RARDQLRERT 1485 Query: 634 QQQ 636 +Q+ Sbjct: 1486 EQE 1488
>gi|12230848|sp|O95049|ZO3_HUMAN Tight junction protein ZO-3 (Zonula occludens 3 protein) (Zona occludens 3 protein) (Tight junction protein 3) Length = 933 Score = 28.5 bits (62), Expect = 8.1 Identities = 11/18 (61%), Positives = 13/18 (72%) Query: 639 PPPPGHSAFAPEFQQTDS 656 PPPP H+ +PE QTDS Sbjct: 324 PPPPRHAQRSPEASQTDS 341
Database: Non-redundant SwissProt sequences Posted date: Mar 15, 2005 10:11 AM Number of letters in database: 60,490,055 Number of sequences in database: 164,271 Lambda K H 0.315 0.130 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 1,516,768 Number of Sequences: 164271 Number of extensions: 69216 Number of successful extensions: 478 Number of sequences better than 10.0: 33 Number of HSP's better than 10.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 339 Number of HSP's gapped (non-prelim): 109 length of query: 689 length of database: 6,424,444 effective HSP length: 102 effective length of query: 587 effective length of database: 5,210,134 effective search space: 3058348658 effective search space used: 3058348658 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
