ORGANISM: Human herpesirus 8
LINEAGE: Viruses; dsDNA viruses, no RNA stage; Herpesviridae; Gammaherpesvirinae; Rhadinovirus
PRODUCT: EBV BLRF1 homolog
GENE: ORF 53
FUNCTION: neutralise antibody responses in the host
CONSERVED DOMAIN:UL73 viral envelope glycoprotein. This family groups together the viral proteins BLRF1, U46, 53, and UL73. The UL73-like envelope glycoproteins, which associates in a high molecular mass complex with its counterpart, gM, induce neutralising antibody responses in the host. These glycoprotein are highly polymorphic, particularly in the N-terminal region.
SCORE: 124 (76% identity)