ORGANISM: Human herpesirus 8

LINEAGE: Viruses; dsDNA viruses, no RNA stage; Herpesviridae; Gammaherpesvirinae; Rhadinovirus

PRODUCT: EBV BLRF1 homolog

GENE: ORF 53

FUNCTION: neutralise antibody responses in the host

CONSERVED DOMAIN:UL73 viral envelope glycoprotein. This family groups together the viral proteins BLRF1, U46, 53, and UL73. The UL73-like envelope glycoproteins, which associates in a high molecular mass complex with its counterpart, gM, induce neutralising antibody responses in the host. These glycoprotein are highly polymorphic, particularly in the N-terminal region.

SCORE: 124 (76% identity)