NCBI Conserved Domain Search
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RPS-BLAST 2.2.8 [Jan-05-2004] Query= local sequence: ref|GENSCAN_predicted_peptide_4|391_aa (391 letters) Database: cdd.v1.65 18,039 PSSMs; 5,506,404 total columns
gnl|CDD|1983 pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E family. These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E
 Domain Relatives
PSSMs producing significant alignments: Score
(bits)
E
value
 
gnl|CDD|1983 pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E family. Thes... 74.9 3e-14


gnl|CDD|1983, pfam01442, Apolipoprotein, Apolipoprotein A1/A4/E family. These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.
             CD-Length = 262 residues, only  77.1% aligned
             Score = 74.9 bits (184), Expect = 3e-14
Query:  78   SRTLKDSLEQDLNNMNKFLEKLR----PLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQ  133
Sbjct:  60   TQELNLLLQDNLDELKSYAEELQEQLGPVAQEFWARLSKETQALRAELGKDLEDVRNRLA  119

Query:  134  PYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDE  193
Sbjct:  120  PYRDELQQMLGQNIEEYRQKLEPLARELRKRLRRDAEELQKRLAPYAEELRERAERNVDA  179

Query:  194  A----WALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARL  249
Sbjct:  180  LRTRLGPYVEQLRQKLTQRLEELRERAQPYAEEYKEQLEEQLSELREKLAPLREDLQEVL  239

Query:  250  SRCVQVLSRKLTLKAKALHARIQQNL  275
Sbjct:  240  NPVLE----QLKTQAEAFQEELKSWL  261

Citing CD-Search: Marchler-Bauer A, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler GH, Mazumder R, Nikolskaya AN, Panchenko AR, Rao BS, Shoemaker BA, Simonyan V, Song JS, Thiessen RA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, and Bryant SH (2003), "CDD: a curated Entrez database of conserved domain alignments", Nucleic Acids Res. 31:383-387.