BLASTP 2.2.8 [Jan-05-2004]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

RID: 1079344528-23810-65857828641.BLASTQ3

Query= hg16_dna|GENSCAN_predicted_peptide_3|1989_aa
         (1989 letters)


Database: Non-redundant SwissProt sequences 
           145,815 sequences; 53,526,777 total letters

 
If you have any problems or questions with the results of this search 
please refer to the BLAST FAQs

Taxonomy reports

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29336545|sp|Q8N3U4|SA2_HUMAN  Cohesin subunit SA-2 (Strom...  2034   0.0   
gi|29336529|sp|O35638|SA2_MOUSE  Cohesin subunit SA-2 (Strom...  2011   0.0   
gi|29336558|sp|Q9DGN0|SA2_XENLA  Cohesin subunit SA-2 (XSA-2...  1843   0.0   
gi|29336549|sp|Q8WVM7|SA1_HUMAN  Cohesin subunit SA-1 (Strom...  1491   0.0   
gi|29336557|sp|Q9D3E6|SA1_MOUSE  Cohesin subunit SA-1 (Strom...  1476   0.0   
gi|29336559|sp|Q9DGN1|SA1_XENLA  Cohesin subunit SA-1 (XSA-1...  1468   0.0   
gi|29336569|sp|Q9UJ98|SA3_HUMAN  Cohesin subunit SA-3 (Strom...   929   0.0   
gi|29336530|sp|O70576|SA3_MOUSE  Cohesin subunit SA-3 (Strom...   902   0.0   
gi|29336522|sp|Q99M76|SA3_RAT  Cohesin subunit SA-3 (Stromal...   901   0.0   
gi|12643387|sp|P98170|BIR4_HUMAN  Baculoviral IAP repeat-con...   639   0.0   
gi|12585185|sp|Q9R0I6|BIR4_RAT  Baculoviral IAP repeat-conta...   578   e-164 
gi|2497241|sp|Q60989|BIR4_MOUSE  Baculoviral IAP repeat-cont...   557   e-158 
gi|2497239|sp|Q62210|BIR2_MOUSE  Baculoviral IAP repeat-cont...   189   5e-47 
gi|2497238|sp|Q13490|BIR2_HUMAN  Baculoviral IAP repeat-cont...   187   3e-46 
gi|2497236|sp|Q13489|BIR3_HUMAN  Baculoviral IAP repeat-cont...   185   8e-46 
gi|2497237|sp|O08863|BIR3_MOUSE  Baculoviral IAP repeat-cont...   174   2e-42 
gi|2497240|sp|Q90660|BIR_CHICK  Inhibitor of apoptosis prote...   171   1e-41 
gi|21759007|sp|Q95M72|BIR8_PANTR  Baculoviral IAP repeat-con...   159   8e-38 
gi|21759006|sp|Q95M71|BIR8_GORGO  Baculoviral IAP repeat-con...   155   7e-37 
gi|21759009|sp|Q96P09|BIR8_HUMAN  Baculoviral IAP repeat-con...   155   1e-36 
gi|2497244|sp|Q24307|IAP2_DROME  Apoptosis 2 inhibitor (Inhi...   127   4e-28 
gi|1170470|sp|P41436|IAP_GVCP  Apoptosis inhibitor IAP            124   3e-27 
gi|12643291|sp|Q13075|BIR1_HUMAN  Baculoviral IAP repeat-con...   123   5e-27 
gi|19855048|sp|O13816|SCC3_SCHPO  Cohesin subunit psc3 (SCC3...   118   1e-25 
gi|12585188|sp|Q9JIB3|BIRG_MOUSE  Baculoviral IAP repeat-con...   117   3e-25 
gi|12643317|sp|Q9R016|BIRE_MOUSE  Baculoviral IAP repeat-con...   117   3e-25 
gi|3914339|sp|O62640|PIAP_PIG  Putative inhibitor of apoptosis    116   5e-25 
gi|12643316|sp|Q9QWK5|BIRA_MOUSE  Baculoviral IAP repeat-con...   116   7e-25 
gi|12643314|sp|Q9JIB6|BIRF_MOUSE  Baculoviral IAP repeat-con...   116   7e-25 
gi|1170471|sp|P41437|IAP3_NPVOP  Apoptosis inhibitor 3 (IAP-3)    115   8e-25 
gi|12643315|sp|Q9QUK4|BIRB_MOUSE  Baculoviral IAP repeat-con...   113   5e-24 
gi|2497243|sp|Q24306|IAP1_DROME  Apoptosis 1 inhibitor (Inhi...   111   2e-23 
gi|731791|sp|P40541|SCC3_YEAST  Cohesin subunit SCC3 (Irregu...    86   9e-16 
gi|21759008|sp|Q96CA5|BIR7_HUMAN  Baculoviral IAP repeat-con...    84   2e-15 
gi|2497245|sp|O10296|IAP1_NPVOP  Apoptosis inhibitor 1 (IAP-1)     79   1e-13 
gi|12585192|sp|Q9NR09|BIR6_HUMAN  Baculoviral IAP repeat-con...    75   2e-12 
gi|33302608|sp|P47732|ZFP_IRV6  Zinc finger protein                72   1e-11 
gi|1170468|sp|P41435|IAP1_NPVAC  Apoptosis inhibitor 1 (IAP-1)     71   3e-11 
gi|12585184|sp|Q9JHY7|BIR5_RAT  Baculoviral IAP repeat-conta...    59   1e-07 
gi|6647548|sp|O70201|BIR5_MOUSE  Baculoviral IAP repeat-cont...    57   3e-07 
gi|3183409|sp|O14064|BIR1_SCHPO  Bir1 protein (Chromosome se...    51   3e-05 
gi|6647543|sp|O15392|BIR5_HUMAN  Baculoviral IAP repeat-cont...    51   3e-05 
gi|1170469|sp|P41454|IAP2_NPVAC  Probable apoptosis inhibito...    44   0.006 
gi|1705854|sp|Q00975|CCAB_HUMAN  Voltage-dependent N-type ca...    42   0.020 
gi|32129904|sp|Q93WF1|PL20_ARATH  Probable pectate lyase 20 ...    40   0.055 
gi|2497248|sp|O11451|IAPL_ASFC3  IAP-like protein p27              37   0.57  
gi|2497250|sp|O11453|IAPL_ASFM2  IAP-like protein p27              36   0.83  
gi|3915379|sp|O25505|ENGA_HELPY  GTP-binding protein engA          36   0.98  
gi|2497247|sp|O12407|IAPL_ASFCH  IAP-like protein p27              35   2.1   
gi|2497249|sp|O11452|IAPL_ASFM1  IAP-like protein p27              35   2.1   
gi|2498837|sp|Q92380|RE11_SCHPO  Meiotic recombination prote...    33   4.9   
gi|24212001|sp|Q979T0|MOAA_THEVO  Probable molybdenum cofact...    33   5.9   
gi|24418590|sp|Q8RFN7|PGK_FUSNN  Phosphoglycerate kinase           33   7.1   

Alignments


>gi|29336545|sp|Q8N3U4|SA2_HUMAN   Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2)
          Length = 1162

 Score = 2034 bits (5270), Expect = 0.0
 Identities = 1020/1156 (88%), Positives = 1020/1156 (88%), Gaps = 76/1156 (6%)

Query: 907  MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG 966
            MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG
Sbjct: 1    MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG 60

Query: 967  VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS 1026
            VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS
Sbjct: 61   VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS 120

Query: 1027 IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 1086
            IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE
Sbjct: 121  IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 180

Query: 1087 AERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXXXXXXX 1146
            AERNKMIGKRAN               NQDEIENMMNAIFKGVFVHRYRD          
Sbjct: 181  AERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICI 240

Query: 1147 XXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS 1206
                 WMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS
Sbjct: 241  EEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS 300

Query: 1207 RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG 1266
            RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG
Sbjct: 301  RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG 360

Query: 1267 EFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 1326
            EFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT
Sbjct: 361  EFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 420

Query: 1327 ELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT 1383
            ELLKDWECMN               DRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT
Sbjct: 421  ELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT 480

Query: 1384 AKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL 1443
            AKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL
Sbjct: 481  AKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL 540

Query: 1444 DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL 1503
            DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL
Sbjct: 541  DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL 600

Query: 1504 EDFLQEGEEPDEDDAY------------------------------------------QI 1521
            EDFLQEGEEPDEDDAY                                          QI
Sbjct: 601  EDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIENGDMPEQI 660

Query: 1522 VIHALQCTHYVILWQLAKITESSSTK-------------------------------AFT 1550
            VIHALQCTHYVILWQLAKITESSSTK                               AFT
Sbjct: 661  VIHALQCTHYVILWQLAKITESSSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFT 720

Query: 1551 ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQE 1610
            ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQE
Sbjct: 721  ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQE 780

Query: 1611 DEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQ 1670
            DEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQ
Sbjct: 781  DEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQ 840

Query: 1671 IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA 1730
            IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA
Sbjct: 841  IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA 900

Query: 1731 IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ 1790
            IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ
Sbjct: 901  IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ 960

Query: 1791 MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQ 1850
            MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQ
Sbjct: 961  MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQ 1020

Query: 1851 XXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHH 1910
                              QTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHH
Sbjct: 1021 LSLTEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHH 1080

Query: 1911 QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE 1970
            QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE
Sbjct: 1081 QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE 1140

Query: 1971 LKPDFFDPASIMDESV 1986
            LKPDFFDPASIMDESV
Sbjct: 1141 LKPDFFDPASIMDESV 1156



>gi|29336529|sp|O35638|SA2_MOUSE   Cohesin subunit SA-2 (Stromal antigen 2) (SCC3 homolog 2)
          Length = 1162

 Score = 2011 bits (5211), Expect = 0.0
 Identities = 1008/1156 (87%), Positives = 1014/1156 (87%), Gaps = 76/1156 (6%)

Query: 907  MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG 966
            MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG
Sbjct: 1    MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG 60

Query: 967  VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS 1026
            VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS
Sbjct: 61   VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS 120

Query: 1027 IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 1086
            IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE
Sbjct: 121  IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 180

Query: 1087 AERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXXXXXXX 1146
            AERNKMIGKRAN               NQDEIENMMNAIFKGVFVHRYR           
Sbjct: 181  AERNKMIGKRANERLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRYAIAEIRAICI 240

Query: 1147 XXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS 1206
                 WMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS
Sbjct: 241  EEIGIWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS 300

Query: 1207 RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG 1266
            RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG
Sbjct: 301  RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG 360

Query: 1267 EFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 1326
            EFLYKKLFSRRDPEEDG+MKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT
Sbjct: 361  EFLYKKLFSRRDPEEDGLMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 420

Query: 1327 ELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT 1383
            ELLKDWECMN               DRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT
Sbjct: 421  ELLKDWECMNSLLLEEPLSGEEALTDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT 480

Query: 1384 AKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL 1443
            AKEKKTQLDDRT+ITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLE  L
Sbjct: 481  AKEKKTQLDDRTRITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLENDL 540

Query: 1444 DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL 1503
            DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL
Sbjct: 541  DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL 600

Query: 1504 EDFLQEGEEPDEDDAY------------------------------------------QI 1521
            EDFLQEGEEPDEDDAY                                          QI
Sbjct: 601  EDFLQEGEEPDEDDAYQVLSTLKRITAFHNAHDLSKWDLFACNYKLLKTGIENGDMPEQI 660

Query: 1522 VIHALQCTHYVILWQLAKITESSSTK-------------------------------AFT 1550
            VIHALQC HYVILWQLAKITES+STK                               AFT
Sbjct: 661  VIHALQCAHYVILWQLAKITESTSTKEDLLRLKKQMRVFCQICQHYLTNVNTTVKEQAFT 720

Query: 1551 ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQE 1610
            ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDD+NSADGQQE
Sbjct: 721  ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDSNSADGQQE 780

Query: 1611 DEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQ 1670
            DEASKIEALHKRRNLLAAFCKLIVYTVVEMN+AADIFKQYMKYYNDYGDIIKETMSKTRQ
Sbjct: 781  DEASKIEALHKRRNLLAAFCKLIVYTVVEMNSAADIFKQYMKYYNDYGDIIKETMSKTRQ 840

Query: 1671 IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA 1730
            IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKE ARRFALTFGLDQLKTREA
Sbjct: 841  IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKEFARRFALTFGLDQLKTREA 900

Query: 1731 IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ 1790
            IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ
Sbjct: 901  IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ 960

Query: 1791 MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQ 1850
            MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISG+SSRGSTVRSKKSKPSTGKRKVVEGMQ
Sbjct: 961  MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGMSSRGSTVRSKKSKPSTGKRKVVEGMQ 1020

Query: 1851 XXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHH 1910
                              QTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQ EHH
Sbjct: 1021 LALPEESSSSDSMWLSREQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQAEHH 1080

Query: 1911 QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE 1970
            QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE
Sbjct: 1081 QTPLDYNRRGTSLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTE 1140

Query: 1971 LKPDFFDPASIMDESV 1986
            LKPDFFDPASIMDESV
Sbjct: 1141 LKPDFFDPASIMDESV 1156



>gi|29336558|sp|Q9DGN0|SA2_XENLA   Cohesin subunit SA-2 (XSA-2) (Stromal antigen 2 homolog) (SCC3
            homolog 2)
          Length = 1194

 Score = 1843 bits (4775), Expect = 0.0
 Identities = 938/1194 (78%), Positives = 987/1194 (82%), Gaps = 120/1194 (10%)

Query: 907  MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKG 966
            MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIE+YKH +D+ALLDLINFFIQCSGCKG
Sbjct: 1    MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIEAYKHSKDVALLDLINFFIQCSGCKG 60

Query: 967  VVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYS 1026
            VV+ EMFRHMQNSEIIR+MTEEFDEDSGDYPLTMAGPQWKKFK SFCEFIGVLVRQCQYS
Sbjct: 61   VVSGEMFRHMQNSEIIRRMTEEFDEDSGDYPLTMAGPQWKKFKFSFCEFIGVLVRQCQYS 120

Query: 1027 IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 1086
            IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE
Sbjct: 121  IIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYE 180

Query: 1087 AERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXXXXXXX 1146
            AERNKMIGKRAN               NQDEIENMMNAIFKGVFVHRYRD          
Sbjct: 181  AERNKMIGKRANDRLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICI 240

Query: 1147 XXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTS 1206
                 WMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYN+ELN+KLELFTS
Sbjct: 241  EEIGVWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNRELNTKLELFTS 300

Query: 1207 RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAG 1266
            RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSS+EVLTAEDCENVYHLVYSAHRPVAVAAG
Sbjct: 301  RFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSDEVLTAEDCENVYHLVYSAHRPVAVAAG 360

Query: 1267 EFLYKKLFSRRDPEEDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 1326
            EFLYKKLFS RDPEEDG+MKRRGR  PNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT
Sbjct: 361  EFLYKKLFSCRDPEEDGIMKRRGRLSPNANLVKTLVFFFLESELHEHAAYLVDSMWDCAT 420

Query: 1327 ELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLT 1383
            ELLKDW+CMN               DRQESALIEI+LCT+RQAAECHPPVGRGTGKRVLT
Sbjct: 421  ELLKDWDCMNSLLLDDPLNGEEALTDRQESALIEILLCTVRQAAECHPPVGRGTGKRVLT 480

Query: 1384 AKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL 1443
            AKEKK+Q+DD+T +TELFAV+LPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL
Sbjct: 481  AKEKKSQMDDKTHLTELFAVSLPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHL 540

Query: 1444 DALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLL 1503
            +ALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTI+NRVDI++SQLIDELADKFNRLL
Sbjct: 541  EALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIYNRVDIAKSQLIDELADKFNRLL 600

Query: 1504 EDFLQEGEEPDEDDAY------------------------------------------QI 1521
            EDFLQE EE DEDDAY                                          QI
Sbjct: 601  EDFLQEEEELDEDDAYQVLSTLKRITAFHNAHDLSRWDLFSGNYKLLKTGIENGDMPEQI 660

Query: 1522 VIHALQCTHYVILWQLAKITESSSTK-------------------------------AFT 1550
            V+HALQCTHYVILWQLAK +E+ S+K                               AFT
Sbjct: 661  VVHALQCTHYVILWQLAKFSETGSSKEELITLKRQMRVFCQICQHYLTNVNTAVKEQAFT 720

Query: 1551 ILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQE 1610
            ILCD+LMIFSHQI+ GGR+ LEPLVY+PDSSLQSELLSFILDHVFI+QDDDN+S+DGQQ+
Sbjct: 721  ILCDVLMIFSHQIVVGGREALEPLVYSPDSSLQSELLSFILDHVFIDQDDDNSSSDGQQD 780

Query: 1611 DEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQ 1670
            DEASKIEALHKRRNLLAAFCKLIVY VVEMNTAADIFKQYM+YYNDYGDIIKETMSKTRQ
Sbjct: 781  DEASKIEALHKRRNLLAAFCKLIVYNVVEMNTAADIFKQYMRYYNDYGDIIKETMSKTRQ 840

Query: 1671 IDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREA 1730
            IDKIQCAKTLILSLQQLFNEMIQE+ YNFDRSS TFS IKELARRFALTFGLDQLKTREA
Sbjct: 841  IDKIQCAKTLILSLQQLFNEMIQEHSYNFDRSSPTFSAIKELARRFALTFGLDQLKTREA 900

Query: 1731 IAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQ 1790
            IAMLHKDGIEFAFKEP+PQGE+HPPLN+AFLDILSEFSSKLLRQDK+TVY YLE+FMTFQ
Sbjct: 901  IAMLHKDGIEFAFKEPSPQGEAHPPLNMAFLDILSEFSSKLLRQDKKTVYAYLERFMTFQ 960

Query: 1791 MSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEGMQ 1850
            MSLRREDVWLPLMSYRNSLLAGGDDDTMSV+SG+S RGS+ RSKK KP TGKRK+     
Sbjct: 961  MSLRREDVWLPLMSYRNSLLAGGDDDTMSVMSGMSGRGSSTRSKKIKPPTGKRKL----- 1015

Query: 1851 XXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKRLRPEDSFMSVYPMQTEHH 1910
                              QT++TPVM+QTPQLTSTIMREPKRLRPE+S+M VYPMQ EHH
Sbjct: 1016 -PEAEESSSSDSMWLNREQTMNTPVMLQTPQLTSTIMREPKRLRPEESYMPVYPMQPEHH 1074

Query: 1911 QTPLDYN--------------------------------------RRGTSLMEDDEEPIV 1932
            Q  LDYN                                      RR T LMEDDEEPIV
Sbjct: 1075 QPSLDYNTQVTWMLAQRQQEEAARQQQERAAMNYVKLRSNLQHAIRRNTGLMEDDEEPIV 1134

Query: 1933 EDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESV 1986
            EDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESV
Sbjct: 1135 EDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESV 1188



>gi|29336549|sp|Q8WVM7|SA1_HUMAN   Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1)
          Length = 1258

 Score = 1491 bits (3860), Expect = 0.0
 Identities = 769/1197 (64%), Positives = 886/1197 (74%), Gaps = 120/1197 (10%)

Query: 902  SGPNRMNGHHQQNGV-ENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQ 960
            +G  R NGH QQNG  E + LFEVVK+GKSAMQSVVDDWIESYK DRDIALLDLINFFIQ
Sbjct: 67   AGRGRANGHPQQNGEGEPVTLFEVVKLGKSAMQSVVDDWIESYKQDRDIALLDLINFFIQ 126

Query: 961  CSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLV 1020
            CSGC+G V  EMFR+MQN+EIIRKMTEEFDEDSGDYPLTM GPQWKKF+S+FCEFIGVL+
Sbjct: 127  CSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFRSNFCEFIGVLI 186

Query: 1021 RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDN 1080
            RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSI+ DN
Sbjct: 187  RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDN 246

Query: 1081 TQRQYEAERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXX 1140
            TQRQYEAERNKMIGKRAN               NQDEIENMMN+IFKG+FVHRYRD    
Sbjct: 247  TQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAE 306

Query: 1141 XXXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSK 1200
                       WMKMYSDAFLNDSYLKYVGWT+HD+QGEVRLKCL ALQ LY N+EL  K
Sbjct: 307  IRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPK 366

Query: 1201 LELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRP 1260
            LELFT+RFKDRIVSMTLDKEYDVAV+AI+L+TL+L  SEE L+ EDCENVYHLVYSAHRP
Sbjct: 367  LELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRP 426

Query: 1261 VAVAAGEFLYKKLFSRRDPE-EDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVD 1319
            VAVAAGEFL+KKLFSR DP+ E+ + KRRGR  PN NL++ LV FFLESELHEHAAYLVD
Sbjct: 427  VAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVD 486

Query: 1320 SMWDCATELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRG 1376
            S+W+ + ELLKDWECM                DRQESALIE+M+CTIRQAAE HPPVGRG
Sbjct: 487  SLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRG 546

Query: 1377 TGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTT 1436
            TGKRVLTAKE+KTQ+DDR K+TE F + LP LL+KYS DAEKV NLLQ+PQYFDLEIY+T
Sbjct: 547  TGKRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYST 606

Query: 1437 GRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELA 1496
            GR+EKHLDALL+QI+ +VEKH ++DVLEACSKTY  LCNEE+TI NRVDI+RSQLIDE  
Sbjct: 607  GRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCNEEYTIQNRVDIARSQLIDEFV 666

Query: 1497 DKFNRLLEDFLQEGEEPDEDDAY------------------------------------- 1519
            D+FN  +ED LQEGEE D+DD Y                                     
Sbjct: 667  DRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFQNAHDLTKWDLFGNCYRLLKTGIEH 726

Query: 1520 -----QIVIHALQCTHYVILWQLAKITESSSTK--------------------------- 1547
                 QIV+ ALQC+HY ILWQL KIT+ S +K                           
Sbjct: 727  GAMPEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTP 786

Query: 1548 ----AFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNN 1603
                AF +LCD+LMIFSHQ+M+GGR+ L+PLV+ PD+ LQSELLSF++DHVFI+QD++N 
Sbjct: 787  VKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQ 846

Query: 1604 SADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKE 1663
            S +G +EDEA+KIEALHKRRNLLAAF KLI+Y +V+M+ AADIFK YMKYYNDYGDIIKE
Sbjct: 847  SMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKE 906

Query: 1664 TMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLD 1723
            T+SKTRQIDKIQCAKTLILSLQQLFNE++QE G N DR+S+  SGIKELARRFALTFGLD
Sbjct: 907  TLSKTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLD 966

Query: 1724 QLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYL 1783
            Q+KTREA+A LHKDGIEFAFK  N +G+ +PP NLAFL++LSEFSSKLLRQDK+TV+ YL
Sbjct: 967  QIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYL 1026

Query: 1784 EKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTM-SVISGISSRGSTVRSKKSKPSTGK 1842
            EKF+T QM  RREDVWLPL+SYRNSL+ GG+DD M       SS+ S+VR+KK +P   K
Sbjct: 1027 EKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHK 1086

Query: 1843 RKVVEGMQXXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKR------LRPE 1896
            ++V +                       + TP  +  PQLTST++RE  R        PE
Sbjct: 1087 KRVED---------ESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPE 1137

Query: 1897 DS------FMSVYPMQTEHHQTPL--DYNRRGTS-----------------LMEDDEEPI 1931
                    F+    MQ      P   D NR+  +                 LME+D EPI
Sbjct: 1138 SEHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVRTGVRHAVRGLMEEDAEPI 1197

Query: 1932 VEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVGL 1988
             EDVMMSS  ++ED+NE  + DTM IDLPPS+NRRER EL+PDFFD A+I+++  G 
Sbjct: 1198 FEDVMMSSRSQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGF 1253



>gi|29336557|sp|Q9D3E6|SA1_MOUSE   Cohesin subunit SA-1 (Stromal antigen 1) (SCC3 homolog 1)
          Length = 1258

 Score = 1476 bits (3821), Expect = 0.0
 Identities = 767/1196 (64%), Positives = 881/1196 (73%), Gaps = 118/1196 (9%)

Query: 902  SGPNRMNGHHQQNGV-ENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQ 960
            +G  R NGH QQNG  + + LFEVVK+GKS MQSVVDDWIE YK DRDIALLDLINFFIQ
Sbjct: 67   AGRGRANGHPQQNGDGDPVTLFEVVKLGKSRMQSVVDDWIELYKQDRDIALLDLINFFIQ 126

Query: 961  CSGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLV 1020
            CSGC+G V  EMFR+MQN+EIIRKMTEEFDEDSGDYPLTM GPQWKKF+S+FCEFIGVL+
Sbjct: 127  CSGCRGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPQWKKFRSNFCEFIGVLI 186

Query: 1021 RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDN 1080
            RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSI+ DN
Sbjct: 187  RQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDN 246

Query: 1081 TQRQYEAERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXX 1140
            TQRQYEAERNKMIGKRAN               NQDEIENMMN+IFKG+FVHRYRD    
Sbjct: 247  TQRQYEAERNKMIGKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAE 306

Query: 1141 XXXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSK 1200
                       WMKMYSDAFLNDSYLKYVGWT+HD+QGEVRLKCL ALQ LY N+EL  K
Sbjct: 307  IRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPK 366

Query: 1201 LELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRP 1260
            LELFT+RFKDRIVSMTLDKEYDVAV+AI+L+TL+L  SEE L+ EDCENVYHLVYSAHRP
Sbjct: 367  LELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRP 426

Query: 1261 VAVAAGEFLYKKLFSRRDPE-EDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVD 1319
            VAVAAGEFL+KKLFSR DP+ E+ + KRRGR  PN NL++ LV FFLESELHEHAAYLVD
Sbjct: 427  VAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNSPNGNLIRMLVLFFLESELHEHAAYLVD 486

Query: 1320 SMWDCATELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRG 1376
            S+W+ + ELLKDWECM                DRQESALIE+M+CTIRQAAE HPPVGRG
Sbjct: 487  SLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRG 546

Query: 1377 TGKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTT 1436
            TGKRVLTAKE+KTQ+DDR K+TE F + LP LL+KYS DAEKV NLLQ+PQYFDLEIY+T
Sbjct: 547  TGKRVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYST 606

Query: 1437 GRLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELA 1496
            GR+EKHLDALL+QI+ +VEKH ++DVLEACSKTY  LC+EE+TI NRVDI+RSQLIDE  
Sbjct: 607  GRMEKHLDALLKQIKFVVEKHVESDVLEACSKTYSILCSEEYTIQNRVDIARSQLIDEFV 666

Query: 1497 DKFNRLLEDFLQEGEEPDEDDAY------------------------------------- 1519
            D+FN  +ED LQEGEE D+DD Y                                     
Sbjct: 667  DRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEH 726

Query: 1520 -----QIVIHALQCTHYVILWQLAKITESSSTK--------------------------- 1547
                 QIV+ ALQC+HY ILWQL KIT+ S +K                           
Sbjct: 727  GAMPEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTP 786

Query: 1548 ----AFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNN 1603
                AF +LCD+LMIFSHQ+M+GGR+ L+PLV+ PD+ LQSELLSF++DHVFI+QD++N 
Sbjct: 787  VKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVFNPDTGLQSELLSFVMDHVFIDQDEENQ 846

Query: 1604 SADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKE 1663
            S +G +EDEA+KIEALHKRRNLLAAF KLI+Y +V+M+ AADIFK YMKYYNDYGDIIKE
Sbjct: 847  SMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKE 906

Query: 1664 TMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLD 1723
            T+SKTRQIDKIQCAKTLILSLQQLFNE++QE G N DR+S+  SGIKELARRFALTFGLD
Sbjct: 907  TLSKTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLD 966

Query: 1724 QLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYL 1783
            Q+KTREA+A LHKDGIEFAFK  N +G+ +PP NLAFL++LSEFSSKLLRQDK+TV+ YL
Sbjct: 967  QIKTREAVATLHKDGIEFAFKYQNQKGQEYPPPNLAFLEVLSEFSSKLLRQDKKTVHSYL 1026

Query: 1784 EKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKR 1843
            EKF+T QM  RREDVWLPL+SYRNSL+ GG+DD MSV SG SS  ++    K       R
Sbjct: 1027 EKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRSKKGRPPLHR 1086

Query: 1844 KVVEGMQXXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKR------LRPED 1897
            K VE                       + TP  + TPQLTST++RE  R        PE 
Sbjct: 1087 KRVE--------DESLDNTWLNRTDTMIQTPGPLPTPQLTSTVLRENSRPMGEQIQEPES 1138

Query: 1898 S------FMSVYPMQTEHHQTPL--DYNRRGTS-----------------LMEDDEEPIV 1932
                   F+    MQ      P   D NR+  +                 LME+D EPI 
Sbjct: 1139 EHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVRAGVRHAVRGLMEEDAEPIF 1198

Query: 1933 EDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVGL 1988
            EDVMMSS  ++ED+NE  + DTM IDLPPS+NRRER EL+PDFFD A+I+++  G 
Sbjct: 1199 EDVMMSSRSQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGF 1253



>gi|29336559|sp|Q9DGN1|SA1_XENLA   Cohesin subunit SA-1 (XSA-1) (Stromal antigen 1 homolog) (SCC3
            homolog 1)
          Length = 1265

 Score = 1468 bits (3801), Expect = 0.0
 Identities = 766/1197 (63%), Positives = 883/1197 (73%), Gaps = 122/1197 (10%)

Query: 903  GPNRMNGHHQQNGV-ENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQC 961
            G  R NGH QQNG  + + LFEVVKMGKSAMQ+VVDDWIESYK DRDIALLDLINFFIQC
Sbjct: 75   GRGRANGHPQQNGEGDPVTLFEVVKMGKSAMQAVVDDWIESYKQDRDIALLDLINFFIQC 134

Query: 962  SGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVR 1021
            SGCKG V  EMFR+MQN+EIIRKMTEEFDEDSGDYPLTM GP WKKF+ +FCEFI VL+R
Sbjct: 135  SGCKGTVRIEMFRNMQNAEIIRKMTEEFDEDSGDYPLTMPGPHWKKFRCNFCEFISVLIR 194

Query: 1022 QCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNT 1081
            QCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSI+ DNT
Sbjct: 195  QCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSIHQDNT 254

Query: 1082 QRQYEAERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXX 1141
            QRQYE ERNK+I KRAN               NQDEIENMMN+IFKG+FVHRYRD     
Sbjct: 255  QRQYETERNKIINKRANERLELLLQKRKELQENQDEIENMMNSIFKGIFVHRYRDAIAEI 314

Query: 1142 XXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKL 1201
                      WMKMYSDAFLNDSYLKYVGWT+HD+QGEVRLKCL ALQ LY N+EL  KL
Sbjct: 315  RAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKL 374

Query: 1202 ELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPV 1261
            ELFT+RFKDRIVSMTLDKEYDVAV+AI+L+TL+L  SEE L+ EDCENVYHLVYSAHRPV
Sbjct: 375  ELFTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPV 434

Query: 1262 AVAAGEFLYKKLFSRRDPE-EDGMMKRRGRQGPNANLVKTLVFFFLESELHEHAAYLVDS 1320
            AVAAGEFL+KKLFSR DP+ E+ + KRRGR  PN NLVK LV FFLESELHEHAAYLVDS
Sbjct: 435  AVAAGEFLHKKLFSRHDPQAEEALAKRRGRSSPNGNLVKMLVLFFLESELHEHAAYLVDS 494

Query: 1321 MWDCATELLKDWECMN---XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGT 1377
            +W+ + ELLKDWECM                +RQESAL+E+M+CTIRQAAE HPPVGRGT
Sbjct: 495  LWESSQELLKDWECMTELLVEEPMQGEEVMSERQESALVELMVCTIRQAAEAHPPVGRGT 554

Query: 1378 GKRVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTG 1437
            GKRVLTAKE+KTQLDD+TK+TE F VALP LL+KYS DAEKV NLLQ+PQYFDLE+Y+TG
Sbjct: 555  GKRVLTAKERKTQLDDKTKLTEHFIVALPVLLSKYSADAEKVANLLQIPQYFDLELYSTG 614

Query: 1438 RLEKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELAD 1497
            R+EKHLD+LL+QIR +VEKH ++DVLEACSKTY  LC+EE+TI NRV+I+ SQLIDELAD
Sbjct: 615  RMEKHLDSLLKQIRFVVEKHIESDVLEACSKTYSILCSEEYTIQNRVEIAHSQLIDELAD 674

Query: 1498 KFNRLLE------------------------------------DF-------LQEGEEPD 1514
            +F+  +E                                    DF       L+ G E  
Sbjct: 675  RFSHAVEELLQEAEEADEDEIYNVMASLKRLTCFHNAHDLTKWDFFGNCYRLLRAGIE-H 733

Query: 1515 EDDAYQIVIHALQCTHYVILWQLAKITESSSTK--------------------------- 1547
            E    QIV+ ALQC+HY ILWQL KITE + +K                           
Sbjct: 734  EGMMEQIVVQALQCSHYSILWQLVKITEGNPSKEEMLALRKTVKSFLAVCQQCLSSMTTL 793

Query: 1548 ----AFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNN 1603
                AF +LCD+LMIFSHQ+ +GGR+ L  LV+ PD  LQSELLSF++DHVFI+QDD+N 
Sbjct: 794  VKEQAFMLLCDLLMIFSHQLTTGGRENLLLLVFNPDVGLQSELLSFVMDHVFIDQDDENQ 853

Query: 1604 SADGQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKE 1663
            S +G +EDEA+KIEALHKRRNLLA+FCKLI+Y +V+MN AADIFK YMKYYNDYGDIIKE
Sbjct: 854  SMEGDEEDEANKIEALHKRRNLLASFCKLIIYDIVDMNAAADIFKHYMKYYNDYGDIIKE 913

Query: 1664 TMSKTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLD 1723
            T+SKTRQ+DKIQCAKTLILSLQQLFNE++QE G N DR+S+  SGIKELARRFALTFGLD
Sbjct: 914  TLSKTRQMDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLD 973

Query: 1724 QLKTREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYL 1783
            Q+KTREA+A LHKDGIEFAFK  NP+G  +PPLNLAFL++LSEFSSKLLRQDK+TV+ YL
Sbjct: 974  QIKTREAVATLHKDGIEFAFKYQNPKGPEYPPLNLAFLEVLSEFSSKLLRQDKKTVHSYL 1033

Query: 1784 EKFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSV-ISGISSRGSTVRSKKSKPSTGK 1842
            EKF+T  M  RREDVWLPL+SYRNSL+ GGD+D +SV   G +S+GS+VRSKK +P   K
Sbjct: 1034 EKFLTDLMMERREDVWLPLISYRNSLVTGGDEDRLSVNSGGSNSKGSSVRSKKGRPPLHK 1093

Query: 1843 RKVVEGMQXXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIMREPKRLRPED----- 1897
            ++V+E                      T+ TP  + TPQLTST++RE  R  PE      
Sbjct: 1094 KRVIE---------EESIDNSWVTRNDTIQTPGALTTPQLTSTVLRENPRQIPEQIPEQE 1144

Query: 1898 -------SFMSVYPMQTE--HHQTPLDYNRRGTS-----------------LMEDDEEPI 1931
                    F+    MQ      Q   D NR+  +                 LMEDD EPI
Sbjct: 1145 SEPSSEPDFLHSPQMQMSWLGQQKLEDLNRKDRTSMSYMKVRSGVRHAVRGLMEDDAEPI 1204

Query: 1932 VEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVGL 1988
             EDVMMSS G++ED+NE  + DTM IDLPPS+NRRER EL+PDFFD A+I+++  G 
Sbjct: 1205 FEDVMMSSRGQLEDMNEEFE-DTMVIDLPPSRNRRERAELRPDFFDSAAIIEDDSGF 1260



>gi|29336569|sp|Q9UJ98|SA3_HUMAN   Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3)
          Length = 1225

 Score =  929 bits (2402), Expect = 0.0
 Identities = 529/1137 (46%), Positives = 693/1137 (60%), Gaps = 125/1137 (10%)

Query: 843  TQETNGDFLGESETHFSSDTDFEDIEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXPPS 902
            T E NGD L   E     DTDFED                                 P  
Sbjct: 36   TSEGNGDSLLADE-----DTDFED----------SLNRNVKKRAAKRPPKTTPVAKHPKK 80

Query: 903  GPNRMNGH-HQQNGVENMMLFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQC 961
            G   ++ H  +Q+      LF  VK  KS MQS+VD+W++SYK D+D   L+L+NFFIQ 
Sbjct: 81   GSRVVHRHSRKQSEPPANDLFNAVKAAKSDMQSLVDEWLDSYKQDQDAGFLELVNFFIQS 140

Query: 962  SGCKGVVTAEMFRHMQNSEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVR 1021
             GCKG+VT EMF+ M NSEII+ +TE+F+EDSGDYPL   GP WKKF+ SFCEF+  LV 
Sbjct: 141  CGCKGIVTPEMFKKMSNSEIIQHLTEQFNEDSGDYPLIAPGPSWKKFQGSFCEFVRTLVC 200

Query: 1022 QCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNT 1081
            QCQYS++YD + MD +ISLLTGLSDSQVRAFRHTSTLAAMKLMT+LV VAL LS++ DN 
Sbjct: 201  QCQYSLLYDGFPMDDLISLLTGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSVHQDNN 260

Query: 1082 QRQYEAERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXX 1141
            QRQYEAERNK  G+RA                +Q+EIE MMNA+F+GVFVHRYRD     
Sbjct: 261  QRQYEAERNKGPGQRAPERLESLLEKRKELQEHQEEIEGMMNALFRGVFVHRYRDVLPEI 320

Query: 1142 XXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKL 1201
                      WM+ YS +FL DSYLKY+GWT+HDK  EVR+KC+ AL+GLY N++L ++L
Sbjct: 321  RAICIEEIGCWMQSYSTSFLTDSYLKYIGWTLHDKHREVRVKCVKALKGLYGNRDLTARL 380

Query: 1202 ELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPV 1261
            ELFTSRFKDR+VSM +D+EY VAV+A++LL L+L++ E +LT  DCE+VY +VY ++R +
Sbjct: 381  ELFTSRFKDRMVSMIMDREYSVAVEAVRLLILILKNMEGLLTDADCESVYPVVYPSNRGL 440

Query: 1262 AVAAGEFLYKKLFSRRDPEEDGMMKRRGRQGPNAN--LVKTLVFFFLESELHEHAAYLVD 1319
            A AAGEFLY KLF   + E   M  R  RQ P A     + L+ FF+ESELH+HAAYLVD
Sbjct: 441  ASAAGEFLYWKLF-YPECEIRTMGGREQRQSPGAQRTFFQLLLSFFVESELHDHAAYLVD 499

Query: 1320 SMWDCATELLKDWECMNXXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGK 1379
            S+WDCA   LKDWE +             D QES LIEI++ + RQA+E HPPVGR TG+
Sbjct: 500  SLWDCAGARLKDWEGLT-SLLLEKDQNLGDVQESTLIEILVSSARQASEGHPPVGRVTGR 558

Query: 1380 RVLTAKEKKTQLDDRTKITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRL 1439
            + LT+KE+KTQ DDR K+TE     LPQLLAK+S DAEKVT LLQL   FDL IY TGRL
Sbjct: 559  KGLTSKERKTQADDRVKLTEHLIPLLPQLLAKFSADAEKVTPLLQLLSCFDLHIYCTGRL 618

Query: 1440 EKHLDALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKF 1499
            EKHL+  L+Q++ +V KH +  VLEA +   + LCN EFT F+R D +RSQL+D L D+F
Sbjct: 619  EKHLELFLQQLQEVVVKHAEPAVLEAGAHALYLLCNPEFTFFSRADFARSQLVDLLTDRF 678

Query: 1500 NRLLEDFLQEGEEPDEDDAY---------------------------------------- 1519
             + LE+ LQ     DED+ Y                                        
Sbjct: 679  QQELEELLQS-SFLDEDEVYNLAATLKRLSAFYNTHDLTRWELYEPCCQLLQKAVDTGEV 737

Query: 1520 --QIVIHALQCTHYVILWQLAKITESSST------------------------------- 1546
              Q+++ AL   ++ ILW L  I++S ++                               
Sbjct: 738  PHQVILPALTLVYFSILWTLTHISKSDASQKQLSSLRDRMVAFCELCQSCLSDVDTEIQE 797

Query: 1547 KAFTILCDILMIFSHQIMSGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSAD 1606
            +AF +L D+L+IFS Q++ GGRD L PLV+ P+++LQSEL SF++DHVFI Q  D  S D
Sbjct: 798  QAFVLLSDLLLIFSPQMIVGGRDFLRPLVFFPEATLQSELASFLMDHVFI-QPGDLGSGD 856

Query: 1607 GQQEDEASKIEALHKRRNLLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMS 1666
             Q++    +IE LH+RR LLA FCKL++Y V+EM+ A+D+FK Y K+YNDYGDIIKET++
Sbjct: 857  SQEDH--LQIERLHQRRRLLAGFCKLLLYGVLEMDAASDVFKHYNKFYNDYGDIIKETLT 914

Query: 1667 KTRQIDKIQCAKTLILSLQQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLK 1726
            + RQID+  C++ L+LSL+QL+ E++QE+G         F  +++LARRFAL+FG  QL+
Sbjct: 915  RARQIDRSHCSRILLLSLKQLYTELLQEHGPQGLNELPAFIEMRDLARRFALSFGPQQLQ 974

Query: 1727 TREAIAMLHKDGIEFAFKEPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKF 1786
             R+ + MLHK+GI+F+  E  P G S+ P NLAFL++LSEFS +L  QDK+ +  YLEK 
Sbjct: 975  NRDLVVMLHKEGIQFSLSELPPAGSSNQPPNLAFLELLSEFSPRLFHQDKQLLLSYLEKC 1034

Query: 1787 MTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVV 1846
            +   +S      W P+ +Y +SL            S + +   T  S +  PS+ KRK V
Sbjct: 1035 LQ-HVSQAPGHPWGPVTTYCHSL------------SPVENTAET--SPQVLPSS-KRKRV 1078

Query: 1847 EGMQXXXXXXXXXXXXXXXXXXQTLHTPVMMQTPQLTSTIM--REP----KRLRPED 1897
            EG                    ++L    +  TP LTST +  R+P    K +  ED
Sbjct: 1079 EG------PAKPNREDVSSSQEESLQLNSIPPTPTLTSTAVKSRQPLWGLKEMEEED 1129



>gi|29336530|sp|O70576|SA3_MOUSE   Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3)
          Length = 1240

 Score =  902 bits (2332), Expect = 0.0
 Identities = 488/1004 (48%), Positives = 642/1004 (63%), Gaps = 100/1004 (9%)

Query: 921  LFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE 980
            LF+ VK  +S MQS+VD+W+++YK D +   L+LINFFI+  GCK  VT EMF+ M NSE
Sbjct: 115  LFDAVKAARSCMQSLVDEWLDNYKQDENAGFLELINFFIRACGCKSTVTPEMFKTMSNSE 174

Query: 981  IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISL 1040
            II+ +TEEF+EDSGDYPLT  GP WKKF+ SFCEF+  LV QCQYS++YD + MD +ISL
Sbjct: 175  IIQHLTEEFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVYQCQYSLLYDGFPMDDLISL 234

Query: 1041 LTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANXX 1100
            L GLSDSQVRAFRHTSTLAAMKLMT+LV VAL LS++ DN QRQYEAERNK   +RA   
Sbjct: 235  LIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPER 294

Query: 1101 XXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXXXXXXXXXXXXWMKMYSDAF 1160
                         NQ++IE MMNAIF+GVFVHRYRD               WM+ YS +F
Sbjct: 295  LESLLEKRKEFQENQEDIEGMMNAIFRGVFVHRYRDILPEIRAICIEEIGYWMQSYSTSF 354

Query: 1161 LNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKE 1220
            LNDSYLKY+GWT+HDK  EVRLKC+ AL GLY N+EL+ ++ELFT+RFKDR+VSM +D+E
Sbjct: 355  LNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQELSLRMELFTNRFKDRMVSMVMDRE 414

Query: 1221 YDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPE 1280
             +VAV+AI+LLTL+L++ E VLT+ DCE +Y +VY ++R +A +AGEF+Y K+F    PE
Sbjct: 415  CEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFH---PE 471

Query: 1281 --EDGMMKRRGRQGPNAN--LVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMN 1336
                 +  R  R+ P A    +  L+ FF+ESE H HAAYLVDS+WDCA   LKDWE + 
Sbjct: 472  CGAKAVSDRERRRSPQAQKTFIYLLLAFFMESEHHNHAAYLVDSLWDCAGSYLKDWESLT 531

Query: 1337 XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDDRTK 1396
                        D QE  LIEI + + RQAAE HPPVGR TGK+ LTAKE+K Q  D+ K
Sbjct: 532  -NLLLQKDQNLGDMQERMLIEIPVSSARQAAEGHPPVGRITGKKSLTAKERKLQAYDKMK 590

Query: 1397 ITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEK 1456
            + E     LPQLL K+S DAE V  LLQL  YFDL IY T RLEKHL+ LL+Q++ +V K
Sbjct: 591  LAEHLIPLLPQLLDKFSADAENVAPLLQLLSYFDLSIYCTQRLEKHLELLLQQLQEVVVK 650

Query: 1457 HTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDED 1516
            H + +VLEA +   + LC  EFT F+RVD +RSQL+D L D+F + L+D +Q     DED
Sbjct: 651  HVEPEVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDFLTDRFQQELDDLMQS-SFLDED 709

Query: 1517 DAY------------------------------------------QIVIHALQCTHYVIL 1534
            + Y                                          Q+++ AL   ++ IL
Sbjct: 710  EVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTGEVPHQVILPALTLVYFSIL 769

Query: 1535 WQLAKITESSSTK------------------------------AFTILCDILMIFSHQIM 1564
            W +  I+ES+S K                              AF +L D+L+IFS Q++
Sbjct: 770  WTVTHISESTSHKQLMSLKKRMVAFCELCQSCLSDVDPEIQEQAFVLLSDLLLIFSPQMI 829

Query: 1565 SGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRN 1624
             GGRD L PLV+ P+++LQSEL SF++DHVF++  +  N   GQ +++  +IE LH+RR 
Sbjct: 830  VGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGN---GQSQEDHVQIELLHQRRR 886

Query: 1625 LLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSL 1684
            LLA FCKL++Y V+E++ A+D+FK Y K+Y DYGDIIKET+++ RQID+ QC++ L+LSL
Sbjct: 887  LLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSL 946

Query: 1685 QQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFK 1744
            +QL+ E+IQE G         F  +++LARRFAL+FG  QL  R+ + MLHK+GI+F+  
Sbjct: 947  KQLYTELIQEQGPQGLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLS 1006

Query: 1745 EPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMS 1804
            E  P G SH P NLAFL++LSEFS +L  QDKR +  YLEK +  ++S      W P+ +
Sbjct: 1007 ELPPAGSSHEPPNLAFLELLSEFSPRLFHQDKRLLLSYLEKCLQ-RVSKAPNHPWGPVTT 1065

Query: 1805 YRNSLLAGGDDDTMSVISGISSRGSTVRSKKSKPSTGKRKVVEG 1848
            Y +SL        + + +  S RG         P   K+K VEG
Sbjct: 1066 YCHSL------HPLEITAEGSPRG---------PPHSKKKCVEG 1094



>gi|29336522|sp|Q99M76|SA3_RAT   Cohesin subunit SA-3 (Stromal antigen 3) (SCC3 homolog 3)
          Length = 1256

 Score =  901 bits (2328), Expect = 0.0
 Identities = 476/965 (49%), Positives = 632/965 (65%), Gaps = 85/965 (8%)

Query: 921  LFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVTAEMFRHMQNSE 980
            LF+ VK  +S  QS+VD+W+E+YK D +   L+L+NFFI+  GCK  VT EMF+ M NSE
Sbjct: 115  LFDAVKAARSCAQSLVDEWLENYKQDENAGFLELVNFFIRACGCKSTVTPEMFKTMSNSE 174

Query: 981  IIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQCQYSIIYDEYMMDTVISL 1040
            II+ +TEEF+EDSGDYPLT  GP WKKF+ SFCEF+  LV QCQYS+++D + MD +ISL
Sbjct: 175  IIQHLTEEFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVCQCQYSLLFDGFPMDDLISL 234

Query: 1041 LTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANXX 1100
            L GLSDSQVRAFRHTSTLAAMKLMT+LV VAL LS++ DN QRQYEAERNK   +RA   
Sbjct: 235  LIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPER 294

Query: 1101 XXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXXXXXXXXXXXXXXWMKMYSDAF 1160
                         NQ+EIE MMNAIF+GVFVHRYRD               WM+ YS +F
Sbjct: 295  LESLLEKRKEFQENQEEIEGMMNAIFRGVFVHRYRDILPEIRAVCIEEIGCWMQSYSTSF 354

Query: 1161 LNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNSKLELFTSRFKDRIVSMTLDKE 1220
            LNDSYLKY+GWT+HDK  EVRLKC+ AL GLY N+EL+S++ELFT+RFKDR+VSM +D+E
Sbjct: 355  LNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQELSSRMELFTNRFKDRMVSMVMDRE 414

Query: 1221 YDVAVQAIKLLTLVLQSSEEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSRRDPE 1280
             +VAV+AI+LLTL+L++ E VLT+ DCE +Y +VY ++R +A +AGEF+Y K+F    PE
Sbjct: 415  SEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFH---PE 471

Query: 1281 --EDGMMKRRGRQGPNAN--LVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWECMN 1336
                 +  R  R+ P A    +  L+ FF+ESE H+HAAYLVDS+WDCA   LKDWE + 
Sbjct: 472  CGAKAVSGRERRRSPQAQRTFIYLLLAFFMESEHHDHAAYLVDSLWDCAGSYLKDWESLT 531

Query: 1337 XXXXXXXXXXXXDRQESALIEIMLCTIRQAAECHPPVGRGTGKRVLTAKEKKTQLDDRTK 1396
                        D QE  LIEI++ + RQAAE HPPVGR TGK+ LTAKE+K Q  D+ K
Sbjct: 532  -SLLLQKDQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKSLTAKERKLQAYDKVK 590

Query: 1397 ITELFAVALPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLDALLRQIRNIVEK 1456
            + E     LPQLLAK+S DAE V  LL+L  YFDL IY T RLEKHL+ LL+Q++ +V K
Sbjct: 591  LAEHLIPLLPQLLAKFSADAENVAPLLRLLSYFDLNIYCTQRLEKHLELLLQQLQEVVVK 650

Query: 1457 HTDTDVLEACSKTYHALCNEEFTIFNRVDISRSQLIDELADKFNRLLEDFLQEGEEPDED 1516
            H + +VLEA +   + LC  EFT F+RVD +RSQL+D L D+F + L+D +Q     DED
Sbjct: 651  HVEPEVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDLLTDRFQQELDDLMQS-SFLDED 709

Query: 1517 DAY------------------------------------------QIVIHALQCTHYVIL 1534
            + Y                                          Q+++ AL   ++ IL
Sbjct: 710  EVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTGEVPHQVILPALTLVYFSIL 769

Query: 1535 WQLAKITESSSTK------------------------------AFTILCDILMIFSHQIM 1564
            W +  I+ES+S K                              AF +L D+L+IFS Q++
Sbjct: 770  WTVTHISESTSQKQLMSLKKRMVAFCELCQSCLSDVDPEIQEQAFVLLSDLLLIFSPQMV 829

Query: 1565 SGGRDMLEPLVYTPDSSLQSELLSFILDHVFIEQDDDNNSADGQQEDEASKIEALHKRRN 1624
             GGRD L PLV+ P+++LQSEL SF++DHVF++  +  N   GQ +++  +IE LH+RR 
Sbjct: 830  VGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGN---GQSQEDHVQIELLHQRRR 886

Query: 1625 LLAAFCKLIVYTVVEMNTAADIFKQYMKYYNDYGDIIKETMSKTRQIDKIQCAKTLILSL 1684
            LLA FCKL++Y V+E++ A+D+FK Y K+Y DYGDIIKET+++ RQID+ QC++ L+LSL
Sbjct: 887  LLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSL 946

Query: 1685 QQLFNEMIQENGYNFDRSSSTFSGIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFK 1744
            +QL+ E+IQE G         F  +++LARRFAL+FG  QL  R+ + MLHK+GI+F+  
Sbjct: 947  KQLYTELIQEQGPQDLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLS 1006

Query: 1745 EPNPQGESHPPLNLAFLDILSEFSSKLLRQDKRTVYVYLEKFMTFQMSLRREDVWLPLMS 1804
            E  P G S  P N+AFL++LSEFS +L  QDK+ +  YLEK +  ++S+     W P+ +
Sbjct: 1007 ELPPAGSSREPPNIAFLELLSEFSPRLFHQDKQLLLSYLEKCLQ-RVSMAPSHPWGPVTT 1065

Query: 1805 YRNSL 1809
            Y +SL
Sbjct: 1066 YCHSL 1070



>gi|12643387|sp|P98170|BIR4_HUMAN   Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
           protein 3) (X-linked inhibitor of apoptosis protein)
           (X-linked IAP) (IAP-like protein) (HILP)
          Length = 497

 Score =  639 bits (1648), Expect = 0.0
 Identities = 292/294 (99%), Positives = 293/294 (99%)

Query: 199 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 258
           MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
Sbjct: 1   MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 60

Query: 259 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 318
           VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
Sbjct: 61  VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 120

Query: 319 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 378
           LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
Sbjct: 121 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 180

Query: 379 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 438
           PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
Sbjct: 181 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 240

Query: 439 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALDD 492
           SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYAL +
Sbjct: 241 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGE 294



 Score =  230 bits (587), Expect = 2e-59
 Identities = 142/336 (42%), Positives = 179/336 (53%), Gaps = 67/336 (19%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RLK+F N+P  + ++   LA AG  YTG GD V+CF C   +  W+  D A   HR+
Sbjct: 163 EEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRR 222

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDR--PSETHADYLLRT 341
             PNC F+ G  L                    N     D  + DR  P+ T+       
Sbjct: 223 HFPNCFFVLGRNL--------------------NIRSESDAVSSDRNFPNSTN------- 255

Query: 342 GQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC 401
                      PRNP+M   EAR+ +F  W     +   +LA AG Y  G GD+V+CF C
Sbjct: 256 ----------LPRNPSMADYEARIFTFGTW--IYSVNKEQLARAGFYALGEGDKVKCFHC 303

Query: 402 GGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMA 461
           GG L +W+P +  W +H + +P C ++L +              + + N+ +L    S+ 
Sbjct: 304 GGGLTDWKPSEDPWEQHAKWYPGCKYLLEQK------------GQEYINNIHLTH--SLE 349

Query: 462 DYEARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKI 521
           +   R         +     L R     +DDTIFQNPMVQEAIRMGFSFKDIKKIMEEKI
Sbjct: 350 ECLVRT--------TEKTPSLTRR----IDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKI 397

Query: 522 QISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQK 557
           QISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQK
Sbjct: 398 QISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQK 433



>gi|12585185|sp|Q9R0I6|BIR4_RAT   Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
           protein 3) (X-linked inhibitor of apoptosis protein)
           (X-linked IAP) (IAP homolog A) (RIAP3) (RIAP-3)
          Length = 496

 Score =  578 bits (1490), Expect = e-164
 Identities = 261/294 (88%), Positives = 279/294 (94%), Gaps = 1/294 (0%)

Query: 199 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 258
           MTFNSFEGS+T VPAD NK+EEFVEEFNRLKTFANFPS SPVSASTLARAGFLYTGEGDT
Sbjct: 1   MTFNSFEGSRTVVPADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDT 60

Query: 259 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 318
           V+CFSCHAAVDRWQYGDSAVGRHR++SPNCRFINGFY EN ATQST+ GIQNGQYK EN 
Sbjct: 61  VQCFSCHAAVDRWQYGDSAVGRHRRISPNCRFINGFYFENGATQSTSPGIQNGQYKSENC 120

Query: 319 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 378
           +G+R+HFALDRPSETHADYLLRTGQVVDISDTIYPRNPAM SEEARLK+FQNWPDYAHL+
Sbjct: 121 VGNRNHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKTFQNWPDYAHLS 180

Query: 379 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 438
           PRELASAGLYYTGI DQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN+N+RSE
Sbjct: 181 PRELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSE 240

Query: 439 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALDD 492
           S  VSSDRNFPNSTN PRNP+MA+Y+ARI TFGTW+YSVNKEQLARAGFYAL +
Sbjct: 241 S-GVSSDRNFPNSTNSPRNPAMAEYDARIVTFGTWLYSVNKEQLARAGFYALGE 293



 Score =  218 bits (554), Expect = 1e-55
 Identities = 134/334 (40%), Positives = 178/334 (53%), Gaps = 64/334 (19%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RLKTF N+P  + +S   LA AG  YTG  D V+CF C   +  W+  D A   HR+
Sbjct: 163 EEARLKTFQNWPDYAHLSPRELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRR 222

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             PNC F+ G               +N   + E+ + S  +F    P+ T++        
Sbjct: 223 HFPNCFFVLG---------------RNVNVRSESGVSSDRNF----PNSTNS-------- 255

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
                    PRNPAM   +AR+ +F  W     +   +LA AG Y  G GD+V+CF CGG
Sbjct: 256 ---------PRNPAMAEYDARIVTFGTW--LYSVNKEQLARAGFYALGEGDKVKCFHCGG 304

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADY 463
            L +W+P +  W +H + +P C ++L                + + N+ +L    S+ + 
Sbjct: 305 GLTDWKPSEDPWEQHAKWYPGCKYLLDEK------------GQEYINNIHLTH--SLGES 350

Query: 464 EARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQI 523
             R         SV K+         +DDTIFQNPMVQEAIRMGF+FKDIKK MEEK+Q 
Sbjct: 351 VVRT---AEKTPSVTKK---------IDDTIFQNPMVQEAIRMGFNFKDIKKTMEEKLQT 398

Query: 524 SGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQK 557
           SGSNY SLEVL+ADLV+AQKD+ QDESSQTSLQK
Sbjct: 399 SGSNYLSLEVLIADLVSAQKDNSQDESSQTSLQK 432



>gi|2497241|sp|Q60989|BIR4_MOUSE   Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
           protein 3) (X-linked inhibitor of apoptosis protein)
           (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3)
          Length = 496

 Score =  557 bits (1436), Expect = e-158
 Identities = 255/294 (86%), Positives = 271/294 (92%), Gaps = 1/294 (0%)

Query: 199 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 258
           MTFNSFEG++T V AD NK+EEFVEEFNRLKTFANFPS SPVSASTLARAGFLYTGEGDT
Sbjct: 1   MTFNSFEGTRTFVLADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDT 60

Query: 259 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 318
           V+CFSCHAA+DRWQYGDSAVGRHR++SPNCRFINGFY EN A QSTN GIQNGQYK EN 
Sbjct: 61  VQCFSCHAAIDRWQYGDSAVGRHRRISPNCRFINGFYFENGAAQSTNPGIQNGQYKSENC 120

Query: 319 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 378
           +G+R+ FA DRP ETHADYLLRTGQVVDISDTIYPRNPAM SEEARLKSFQNWPDYAHLT
Sbjct: 121 VGNRNPFAPDRPPETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKSFQNWPDYAHLT 180

Query: 379 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 438
           PRELASAGLYYTG  DQVQCFCCGGKL+NWEPCDRAWSEHRRHFPNCFFVLGRN+N+RSE
Sbjct: 181 PRELASAGLYYTGADDQVQCFCCGGKLENWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSE 240

Query: 439 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALDD 492
           S  VSSDRNFPNSTN PRNP+MA+YEARI TFGTW  SVNKEQLARAGFYAL +
Sbjct: 241 S-GVSSDRNFPNSTNSPRNPAMAEYEARIVTFGTWTSSVNKEQLARAGFYALGE 293



 Score =  217 bits (553), Expect = 2e-55
 Identities = 131/334 (39%), Positives = 179/334 (53%), Gaps = 64/334 (19%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RLK+F N+P  + ++   LA AG  YTG  D V+CF C   ++ W+  D A   HR+
Sbjct: 163 EEARLKSFQNWPDYAHLTPRELASAGLYYTGADDQVQCFCCGGKLENWEPCDRAWSEHRR 222

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             PNC F+ G               +N   + E+ + S  +F    P+ T++        
Sbjct: 223 HFPNCFFVLG---------------RNVNVRSESGVSSDRNF----PNSTNS-------- 255

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
                    PRNPAM   EAR+ +F  W   + +   +LA AG Y  G GD+V+CF CGG
Sbjct: 256 ---------PRNPAMAEYEARIVTFGTWT--SSVNKEQLARAGFYALGEGDKVKCFHCGG 304

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADY 463
            L +W+P +  W +H + +P C ++L                + + N+ +L  +      
Sbjct: 305 GLTDWKPSEDPWEQHAKWYPGCKYLLDEK------------GQEYINNIHLTHS-----L 347

Query: 464 EARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQI 523
           E  +        S+ K+         +DDTIFQNPMVQEAIRMGFSFKDIKK MEEKIQ 
Sbjct: 348 EESLGRTAEKTPSLTKK---------IDDTIFQNPMVQEAIRMGFSFKDIKKTMEEKIQT 398

Query: 524 SGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQK 557
           SGS+Y SLEVL+ADLV+AQKD+ +DESSQTSLQK
Sbjct: 399 SGSSYLSLEVLIADLVSAQKDNTEDESSQTSLQK 432



>gi|2497239|sp|Q62210|BIR2_MOUSE   Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
           protein 2) (MIAP2) (MIAP-2)
          Length = 612

 Score =  189 bits (480), Expect = 5e-47
 Identities = 119/298 (39%), Positives = 158/298 (53%), Gaps = 43/298 (14%)

Query: 208 KTCVPADINKEEE------FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRC 261
           K+ + ++  KE E      F  E  R+ T++ FP G PVS  +LARAGF YTG  D V+C
Sbjct: 24  KSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKC 83

Query: 262 FSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGS 321
           F C   +D W+ GDS V +HR+  P+C F+    L +++ QS +          +N    
Sbjct: 84  FCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQT--LLSASLQSPS----------KNMSPV 131

Query: 322 RDHFALDRPSE---THADYL---LRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYA 375
           +  FA   P E    H++     L +  V D S  + P + AM +EEAR  ++  WP  +
Sbjct: 132 KSRFAHSSPLERGGIHSNLCSSPLNSRAVEDFSSRMDPCSYAMSTEEARFLTYSMWP-LS 190

Query: 376 HLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNI 435
            L+P ELA AG YY G GD+V CF CGGKL NWEP D A SEHRRHFP+C F+       
Sbjct: 191 FLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFL------- 243

Query: 436 RSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALD 491
               +  S  + F  S     N SM  + AR+ TF  W  S  V  EQLA AGFY +D
Sbjct: 244 ----ENTSETQRFSIS-----NLSMQTHSARLRTFLYWPPSVPVQPEQLASAGFYYVD 292



 Score =  135 bits (340), Expect = 1e-30
 Identities = 96/324 (29%), Positives = 144/324 (44%), Gaps = 75/324 (23%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  R  T++ +P  S +S + LARAGF Y G GD V CF+C   +  W+  D A+  HR+
Sbjct: 177 EEARFLTYSMWPL-SFLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRR 235

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             P+C F     LEN+                               SET         Q
Sbjct: 236 HFPHCPF-----LENT-------------------------------SET---------Q 250

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
              IS      N +M +  ARL++F  WP    + P +LASAG YY    D V+CFCC G
Sbjct: 251 RFSIS------NLSMQTHSARLRTFLYWPPSVPVQPEQLASAGFYYVDRNDDVKCFCCDG 304

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPN------STNLPRN 457
            L+ WEP D  W EH + FP C F+    + ++ +         +P+      ST+    
Sbjct: 305 GLRCWEPGDDPWIEHAKWFPRCEFL----IRMKGQEFVDEIQARYPHLLEQLLSTSDTPG 360

Query: 458 PSMADYEARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIM 517
              AD    +  FG              G  + D  +   P+V+ A+ MGFS   +++ +
Sbjct: 361 EENADPTETVVHFG-------------PGESSEDVVMMSTPVVKAALEMGFSRSLVRQTV 407

Query: 518 EEKIQISGSNYKSLEVLVADLVNA 541
           + +I  +G NY+++  +V+ L+NA
Sbjct: 408 QRQILATGENYRTVNDIVSVLLNA 431



>gi|2497238|sp|Q13490|BIR2_HUMAN   Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
           protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF
           signaling complex protein 2) (IAP homolog B)
          Length = 618

 Score =  187 bits (474), Expect = 3e-46
 Identities = 110/278 (39%), Positives = 146/278 (52%), Gaps = 32/278 (11%)

Query: 220 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           +F  E  R+ T++ FP+G PVS  +LARAGF YTG  D V+CF C   +D W+ GDS + 
Sbjct: 42  DFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQ 101

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQY------KVENYLGSRDHFALDRPSET 333
           +H+++ P+C FI      +  + S N+      +       +E+       ++   P+  
Sbjct: 102 KHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNP- 160

Query: 334 HADYLLRTGQVVDISDT-IYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGI 392
                L +  V DIS +   P + AM +EEAR  ++  WP    L+P ELA AG YY G 
Sbjct: 161 -----LNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWP-LTFLSPSELARAGFYYIGP 214

Query: 393 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNST 452
           GD+V CF CGGKL NWEP D A SEHRRHFPNC F+      +R           F  S 
Sbjct: 215 GDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLETLR-----------FSIS- 262

Query: 453 NLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFY 488
               N SM  + AR+ TF  W  S  V  EQLA AGFY
Sbjct: 263 ----NLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFY 296



 Score =  136 bits (342), Expect = 5e-31
 Identities = 91/309 (29%), Positives = 137/309 (44%), Gaps = 77/309 (24%)

Query: 240 VSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENS 299
           +S S LARAGF Y G GD V CF+C   +  W+  D A+  HR+  PNC F     LENS
Sbjct: 199 LSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPF-----LENS 253

Query: 300 ATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMY 359
                   ++  ++ + N                                       +M 
Sbjct: 254 --------LETLRFSISNL--------------------------------------SMQ 267

Query: 360 SEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHR 419
           +  AR+++F  WP    + P +LASAG YY G  D V+CFCC G L+ WE  D  W EH 
Sbjct: 268 THAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHA 327

Query: 420 RHFPNCFFVLGRNLNIRSESDAVSSDRNFPN------STNLPRNPSMADYEARIFTFGTW 473
           + FP C F+    + ++ +         +P+      ST+       AD    I  FG  
Sbjct: 328 KWFPRCEFL----IRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENAD--PPIIHFG-- 379

Query: 474 IYSVNKEQLARAGFYALDDTIFQN-PMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLE 532
                       G  + +D +  N P+V+ A+ MGF+   +K+ ++ KI  +G NYK++ 
Sbjct: 380 -----------PGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVN 428

Query: 533 VLVADLVNA 541
            +V+ L+NA
Sbjct: 429 DIVSALLNA 437



 Score = 62.4 bits (150), Expect = 1e-08
 Identities = 27/65 (41%), Positives = 34/65 (52%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           R++TF  +PS  PV    LA AGF Y G  D V+CF C   +  W+ GD     H K  P
Sbjct: 272 RMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFP 331

Query: 287 NCRFI 291
            C F+
Sbjct: 332 RCEFL 336



>gi|2497236|sp|Q13489|BIR3_HUMAN   Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
           protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF
           signaling complex protein 1) (IAP homolog C) (Apoptosis
           inhibitor 2) (API2)
          Length = 604

 Score =  185 bits (470), Expect = 8e-46
 Identities = 113/287 (39%), Positives = 149/287 (51%), Gaps = 45/287 (15%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  R+ T++ FP+G PVS  +LARAGF YTG  D V+CF C   +D W+ GDS   +H+K
Sbjct: 29  ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKK 88

Query: 284 VSPNCRFINGFYLEN------------SATQSTNS---GIQNGQYKVENYLGSRDHFALD 328
           + P+CRF+      N            S T ST+S   G +N  Y   +Y  S  +    
Sbjct: 89  LYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNS 148

Query: 329 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 388
           R ++  +  L+R+             + AM +E ARL +FQ WP    L+P +LA AG Y
Sbjct: 149 RANQDFS-ALMRSSY-----------HCAMNNENARLLTFQTWP-LTFLSPTDLAKAGFY 195

Query: 389 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 448
           Y G GD+V CF CGGKL NWEP D A SEH RHFP C F+         E+    + R  
Sbjct: 196 YIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFI---------ENQLQDTSRYT 246

Query: 449 PNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALDDT 493
            +      N SM  + AR  TF  W  S  VN EQLA AGFY + ++
Sbjct: 247 VS------NLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNS 287



 Score =  128 bits (322), Expect = 1e-28
 Identities = 90/313 (28%), Positives = 135/313 (43%), Gaps = 77/313 (24%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RL TF  +P  + +S + LA+AGF Y G GD V CF+C   +  W+  D+A+  H +
Sbjct: 169 ENARLLTFQTWPL-TFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLR 227

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             P C FI     EN    ++       +Y V N                          
Sbjct: 228 HFPKCPFI-----ENQLQDTS-------RYTVSNL------------------------- 250

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
                        +M +  AR K+F NWP    + P +LASAG YY G  D V+CFCC G
Sbjct: 251 -------------SMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDG 297

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPN------STNLPRN 457
            L+ WE  D  W +H + FP C +++     I+ +        ++P+      ST+   +
Sbjct: 298 GLRCWESGDDPWVQHAKWFPRCEYLI----RIKGQEFIRQVQASYPHLLEQLLSTS--DS 351

Query: 458 PSMADYEARIFTFGTWIYSVNKEQLARAGFYALDDTIFQN-PMVQEAIRMGFSFKDIKKI 516
           P   + E+ I  F               G    +D I  N P++  A+ MGFS   +K+ 
Sbjct: 352 PGDENAESSIIHF-------------EPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQT 398

Query: 517 MEEKIQISGSNYK 529
           ++ KI  +G NY+
Sbjct: 399 VQRKILATGENYR 411



>gi|2497237|sp|O08863|BIR3_MOUSE   Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
           protein 1) (MIAP1) (MIAP-1)
          Length = 600

 Score =  174 bits (442), Expect = 2e-42
 Identities = 109/282 (38%), Positives = 145/282 (51%), Gaps = 37/282 (13%)

Query: 220 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           +F  E  RL T++ FP G PVS  +LARAGF YTG  D V+CF C   +D W+ GDS + 
Sbjct: 23  DFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPME 82

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKV--------EN---YLGSRDHFALD 328
           +HRK+ P+C F+      NS   S    + +             EN   + GS   F  D
Sbjct: 83  KHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSD 142

Query: 329 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 388
             +        R  Q      T  P + AM +E+ARL +++ WP  + L+P +LA AG Y
Sbjct: 143 PVN-------FRANQDCPALST-SPYHFAMNTEKARLLTYETWP-LSFLSPAKLAKAGFY 193

Query: 389 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 448
           Y G GD+V CF C GKL NWE  D A SEH+RHFP+C F+  ++L   +    VS     
Sbjct: 194 YIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFL--KDLGQSASRYTVS----- 246

Query: 449 PNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFY 488
                   N SM  + ARI TF  W  S  V+ ++LA AGFY
Sbjct: 247 --------NLSMQTHAARIRTFSNWPSSALVHSQELASAGFY 280



 Score =  141 bits (355), Expect = 2e-32
 Identities = 93/325 (28%), Positives = 147/325 (45%), Gaps = 72/325 (22%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RL T+  +P  S +S + LA+AGF Y G GD V CF+C   +  W+  D A+  H++
Sbjct: 167 EKARLLTYETWPL-SFLSPAKLAKAGFYYIGPGDRVACFACDGKLSNWERKDDAMSEHQR 225

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             P+C F+    L  SA++ T S                                     
Sbjct: 226 HFPSCPFLKD--LGQSASRYTVS------------------------------------- 246

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
                      N +M +  AR+++F NWP  A +  +ELASAG YYTG  D V+CFCC G
Sbjct: 247 -----------NLSMQTHAARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDG 295

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPN----STNLPRNPS 459
            L+ WE  D  W EH + FP C ++    L I+ +         +P+      +   +P 
Sbjct: 296 GLRCWESGDDPWVEHAKWFPRCEYL----LRIKGQEFVSQVQAGYPHLLEQLLSTSDSPE 351

Query: 460 MADYEARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEE 519
             + +A I  FG              G  + D  +   P+V+ A+ MGFS   +++ ++ 
Sbjct: 352 DENADAAIVHFG-------------PGESSEDVVMMSTPVVKAALEMGFSRSLVRQTVQR 398

Query: 520 KIQISGSNYKSLEVLVADLVNAQKD 544
           +I  +G NY+++  LV  L++A+ +
Sbjct: 399 QILATGENYRTVSDLVIGLLDAEDE 423



>gi|2497240|sp|Q90660|BIR_CHICK   Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis
           protein)
          Length = 611

 Score =  171 bits (433), Expect = 1e-41
 Identities = 114/290 (39%), Positives = 144/290 (49%), Gaps = 47/290 (16%)

Query: 220 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           +F  E  R+ TF+ FP   PVS   LARAGF YTG  D V+CFSC   +D WQ GD+A+ 
Sbjct: 26  DFSCELYRMSTFSTFPVNVPVSERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAME 85

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSG-----------------IQNGQYKVENYLGSR 322
           +H++V P+C F+      N+   ST+S                  +     +V  + GS 
Sbjct: 86  KHKQVYPSCSFVQNMLSLNNLGLSTHSAFSPLVASNLSPSLRSMTLSPSFEQVGYFSGSF 145

Query: 323 DHFALDRPSETHADYL--LRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPR 380
             F  D  +   A+ L  LR+            +NP+M +EEARL++   WP    L P 
Sbjct: 146 SSFPRDPVTTRAAEDLSHLRSKL----------QNPSMSTEEARLRTSHAWP-LMCLWPA 194

Query: 381 ELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESD 440
           E+A AGL   G  D+V C  CG KL NWEP D A SEHRRHFPNC FV   NL     S 
Sbjct: 195 EVAKAGLDDLGTADKVACVNCGVKLSNWEPKDNAMSEHRRHFPNCPFV--ENLMRDQPSF 252

Query: 441 AVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI--YSVNKEQLARAGFY 488
            VS             N +M  +EAR+ TF  W     V  EQLA AGFY
Sbjct: 253 NVS-------------NVTMQTHEARVKTFINWPTRIPVQPEQLADAGFY 289



 Score =  122 bits (305), Expect = 1e-26
 Identities = 88/304 (28%), Positives = 131/304 (43%), Gaps = 72/304 (23%)

Query: 243 STLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQ 302
           + +A+AG    G  D V C +C   +  W+  D+A+  HR+  PNC F            
Sbjct: 194 AEVAKAGLDDLGTADKVACVNCGVKLSNWEPKDNAMSEHRRHFPNCPF------------ 241

Query: 303 STNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEE 362
                       VEN +        D+PS              ++S      N  M + E
Sbjct: 242 ------------VENLM-------RDQPS-------------FNVS------NVTMQTHE 263

Query: 363 ARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHF 422
           AR+K+F NWP    + P +LA AG YY G  D V+CFCC G L+ WE  D  W EH + F
Sbjct: 264 ARVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWIEHAKWF 323

Query: 423 PNCFFVLGRNLNIRSESDAVSSDRNFP----NSTNLPRNPSMADYEARIFTFGTWIYSVN 478
           P C ++    L ++           FP    NS+    +  + +    I  F        
Sbjct: 324 PRCEYL----LRVKGGEFVSQVQARFPHLLWNSSCTTSDKPVDENMDPIIHF-------- 371

Query: 479 KEQLARAGFYALDDTIFQN-PMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVAD 537
                  G    +D I  N P+V+ A+ MGFS + IK+ ++ KI  +  NYK++  LV++
Sbjct: 372 -----EPGESPSEDAIMMNTPVVKAALEMGFSRRLIKQTVQSKILATEENYKTVNDLVSE 426

Query: 538 LVNA 541
           L+ A
Sbjct: 427 LLTA 430



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 27/65 (41%), Positives = 35/65 (53%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           R+KTF N+P+  PV    LA AGF Y G  D V+CF C   +  W+ GD     H K  P
Sbjct: 265 RVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWIEHAKWFP 324

Query: 287 NCRFI 291
            C ++
Sbjct: 325 RCEYL 329



>gi|21759007|sp|Q95M72|BIR8_PANTR   Baculoviral IAP repeat-containing protein 8 (Inhibitor of
           apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
          Length = 236

 Score =  159 bits (401), Expect = 8e-38
 Identities = 88/200 (44%), Positives = 118/200 (59%), Gaps = 28/200 (14%)

Query: 358 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 417
           M   EARL +F  W  +  +   +LA AG Y  G  D+VQCF CGG L NW+P +  W +
Sbjct: 1   MTGYEARLITFGTWMYF--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58

Query: 418 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV 477
           H + +P C ++L                  + N+ +L R+      E  +        S+
Sbjct: 59  HAKWYPGCKYLLEEK------------GHEYINNIHLTRS-----LEGALVQTTKKTPSL 101

Query: 478 NKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVAD 537
            K          ++DTIF NPM+QEAIRMGF FKD+KKIMEE+IQ SGSNYK+LEVLVAD
Sbjct: 102 TKR---------INDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLVAD 152

Query: 538 LVNAQKDSMQDESSQTSLQK 557
           LV+AQKD+ ++ES+QTSLQ+
Sbjct: 153 LVSAQKDTTENESNQTSLQR 172



 Score = 43.5 bits (101), Expect = 0.005
 Identities = 18/52 (34%), Positives = 28/52 (53%)

Query: 240 VSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 291
           V+   LARAGF   G+ D V+CF C   +  W+  +    +H K  P C+++
Sbjct: 18  VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYL 69



>gi|21759006|sp|Q95M71|BIR8_GORGO   Baculoviral IAP repeat-containing protein 8 (Inhibitor of
           apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
          Length = 236

 Score =  155 bits (393), Expect = 7e-37
 Identities = 88/200 (44%), Positives = 115/200 (57%), Gaps = 28/200 (14%)

Query: 358 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 417
           M   EA L +F  W     +   +LA AG Y  G  D++QCF CGG L NW+P +  W +
Sbjct: 1   MTGYEAWLITFGTW--MYSVNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQ 58

Query: 418 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV 477
           H + +P C ++L                  + N+ +L R+      E  +        S+
Sbjct: 59  HAKWYPGCKYLLEEK------------GHEYINNIHLTRS-----LEGALVQTTKKTPSL 101

Query: 478 NKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVAD 537
            K          + DTIF NPM+QEAIRMGF FKDIKKIMEEKIQ SGSNYK+LEVLVAD
Sbjct: 102 TKR---------ISDTIFPNPMLQEAIRMGFDFKDIKKIMEEKIQTSGSNYKTLEVLVAD 152

Query: 538 LVNAQKDSMQDESSQTSLQK 557
           LV+AQKD+ ++ES+QTSLQ+
Sbjct: 153 LVSAQKDTTENESNQTSLQR 172



 Score = 43.1 bits (100), Expect = 0.007
 Identities = 17/52 (32%), Positives = 28/52 (53%)

Query: 240 VSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 291
           V+   LARAGF   G+ D ++CF C   +  W+  +    +H K  P C+++
Sbjct: 18  VNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYL 69



>gi|21759009|sp|Q96P09|BIR8_HUMAN   Baculoviral IAP repeat-containing protein 8 (Inhibitor of
           apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
           (Testis-specific inhibitor of apoptosis)
          Length = 236

 Score =  155 bits (391), Expect = 1e-36
 Identities = 87/200 (43%), Positives = 115/200 (57%), Gaps = 28/200 (14%)

Query: 358 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 417
           M   EARL +F  W     +   +LA AG Y  G  D+VQCF CGG L NW+P +  W +
Sbjct: 1   MTGYEARLITFGTW--MYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58

Query: 418 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV 477
           H + +P C ++L                  + N+ +L R+      E  +        S+
Sbjct: 59  HAKWYPGCKYLLEEK------------GHEYINNIHLTRS-----LEGALVQTTKKTPSL 101

Query: 478 NKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVAD 537
            K          + DTIF NPM+QEAIRMGF FKD+KKIMEE+IQ SGSNYK+LEVLVAD
Sbjct: 102 TKR---------ISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLVAD 152

Query: 538 LVNAQKDSMQDESSQTSLQK 557
           LV+AQKD+ ++E +QTSLQ+
Sbjct: 153 LVSAQKDTTENELNQTSLQR 172



 Score = 44.3 bits (103), Expect = 0.003
 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           RL TF  +     V+   LARAGF   G+ D V+CF C   +  W+  +    +H K  P
Sbjct: 7   RLITFGTWMYS--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYP 64

Query: 287 NCRFI 291
            C+++
Sbjct: 65  GCKYL 69



>gi|2497244|sp|Q24307|IAP2_DROME   Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP)
           (IAP homolog A) (IAP-like protein) (DILP)
          Length = 498

 Score =  127 bits (318), Expect = 4e-28
 Identities = 87/273 (31%), Positives = 117/273 (42%), Gaps = 56/273 (20%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           RL TF  +P  +PVSA  L   GF  TG      C  CH  +DRW+YGD    RHR+ SP
Sbjct: 12  RLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSP 71

Query: 287 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 346
            C  +                         N+ G+     + R  E+  +       VVD
Sbjct: 72  ICSMV----------------------LAPNHCGN-----VPRSQESDNE----GNSVVD 100

Query: 347 ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLK 406
             ++     P +  E  RL +F++WP+  ++TP+ LA AG YY    D V+C  C G + 
Sbjct: 101 SPESC--SCPDLLLEANRLVTFKDWPN-PNITPQALAKAGFYYLNRLDHVKCVWCNGVIA 157

Query: 407 NWEPCDRAWSEHRRHFPNC---------FFVLGRNLNIRSESDAVSSDRNFPNSTNLPRN 457
            WE  D A+ EH+R FP C          F  G+NL           D      T LP  
Sbjct: 158 KWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNL-----------DELGIQPTTLPLR 206

Query: 458 PSMADYEARIFTFGTWIYSVNK--EQLARAGFY 488
           P  A  +AR+ TF  W  S  +    LA+AG Y
Sbjct: 207 PKYACVDARLRTFTDWPISNIQPASALAQAGLY 239



 Score =  106 bits (265), Expect = 5e-22
 Identities = 88/358 (24%), Positives = 140/358 (39%), Gaps = 90/358 (25%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E NRL TF ++P+ + ++   LA+AGF Y    D V+C  C+  + +W+  D+A   H++
Sbjct: 113 EANRLVTFKDWPNPN-ITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKR 171

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             P C  +                           +G    FA              TG+
Sbjct: 172 FFPQCPRVQ--------------------------MGPLIEFA--------------TGK 191

Query: 344 VVD---ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFC 400
            +D   I  T  P  P     +ARL++F +WP         LA AGLYY  IGDQV+CF 
Sbjct: 192 NLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFH 251

Query: 401 CGGKLKNWEPCDRAWSEHRRHFPNCFFV-LGRNLNIRSESDAVSSDRNFPNSTNLPRNPS 459
           C   L++W+  D  W EH +  P C FV L +     SE  A ++     N+++ P    
Sbjct: 252 CNIGLRSWQKEDEPWFEHAKWSPKCQFVLLAKGPAYVSEVLATTA----ANASSPPATAP 307

Query: 460 MADYEARIFTFGTWIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKDIKKIMEE 519
               +A                          D +      +EA+ +G     ++  ++ 
Sbjct: 308 APTLQA--------------------------DVLMDEAPAKEALALGIDGGVVRNAIQR 341

Query: 520 KIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKGKSGALEGIGPPRVFLPRVK 577
           K+  SG  + +L+ L+ D+ +                 G   ALE   PP    P ++
Sbjct: 342 KLLSSGCAFSTLDELLHDIFD---------------DAGAGAALEVREPPEPSAPFIE 384



 Score = 62.8 bits (151), Expect = 8e-09
 Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 3/138 (2%)

Query: 357 AMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWS 416
            M  E  RL +F  WP  A ++  +L + G + TG   + +C  C  ++  WE  D+   
Sbjct: 5   GMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAE 64

Query: 417 EHRRHFPNCFFVLGRNL--NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI 474
            HRR  P C  VL  N   N+    ++ +   +  +S      P +     R+ TF  W 
Sbjct: 65  RHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCPDLLLEANRLVTFKDWP 124

Query: 475 Y-SVNKEQLARAGFYALD 491
             ++  + LA+AGFY L+
Sbjct: 125 NPNITPQALAKAGFYYLN 142



>gi|1170470|sp|P41436|IAP_GVCP   Apoptosis inhibitor IAP
          Length = 275

 Score =  124 bits (311), Expect = 3e-27
 Identities = 70/203 (34%), Positives = 92/203 (45%), Gaps = 38/203 (18%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           RL TF  +P  S +S  T+A+ GF Y G  D VRC  C   + RW+ G+     H+K +P
Sbjct: 10  RLNTFEKWPV-SFLSPETMAKNGFYYLGRSDEVRCAFCKVEIMRWKEGEDPAADHKKWAP 68

Query: 287 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 346
            C F+ G                       +  GS       + + TH            
Sbjct: 69  QCPFVKGI----------------------DVCGSIVTTNNIQNTTTH------------ 94

Query: 347 ISDTIY-PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKL 405
             DTI  P +P    E AR+KSF NWP      P ++A AG +YTG GD  +CF C G L
Sbjct: 95  --DTIIGPAHPKYAHEAARVKSFHNWPRCMKQRPEQMADAGFFYTGYGDNTKCFYCDGGL 152

Query: 406 KNWEPCDRAWSEHRRHFPNCFFV 428
           K+WEP D  W +H R F  C +V
Sbjct: 153 KDWEPEDVPWEQHVRWFDRCAYV 175



 Score = 70.1 bits (170), Expect = 5e-11
 Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 3/130 (2%)

Query: 361 EEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRR 420
           EE RL +F+ WP  + L+P  +A  G YY G  D+V+C  C  ++  W+  +   ++H++
Sbjct: 7   EEVRLNTFEKWP-VSFLSPETMAKNGFYYLGRSDEVRCAFCKVEIMRWKEGEDPAADHKK 65

Query: 421 HFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNK- 479
             P C FV G ++     +     +    ++   P +P  A   AR+ +F  W   + + 
Sbjct: 66  WAPQCPFVKGIDVCGSIVTTNNIQNTTTHDTIIGPAHPKYAHEAARVKSFHNWPRCMKQR 125

Query: 480 -EQLARAGFY 488
            EQ+A AGF+
Sbjct: 126 PEQMADAGFF 135



 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 22/72 (30%), Positives = 35/72 (48%)

Query: 220 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           ++  E  R+K+F N+P         +A AGF YTG GD  +CF C   +  W+  D    
Sbjct: 104 KYAHEAARVKSFHNWPRCMKQRPEQMADAGFFYTGYGDNTKCFYCDGGLKDWEPEDVPWE 163

Query: 280 RHRKVSPNCRFI 291
           +H +    C ++
Sbjct: 164 QHVRWFDRCAYV 175



>gi|12643291|sp|Q13075|BIR1_HUMAN   Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis
           inhibitory protein)
          Length = 1403

 Score =  123 bits (308), Expect = 5e-27
 Identities = 89/272 (32%), Positives = 129/272 (47%), Gaps = 54/272 (19%)

Query: 221 FVEEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           + EE  RL +F N+P     +S   L+ AGF++TG+ DTV+CFSC   +  W+ GD    
Sbjct: 156 YQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWK 215

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRD----HFA---LDRPSE 332
            H K  P C F+          +S  S  +  QY +++Y G  D    HF    + R   
Sbjct: 216 EHAKWFPKCEFL----------RSKKSSEEITQY-IQSYKGFVDITGEHFVNSWVQRELP 264

Query: 333 THADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGI 392
             + Y          +D+I+        EE RL SF++WP  + +    LA AGL+YTGI
Sbjct: 265 MASAY---------CNDSIFAY------EELRLDSFKDWPRESAVGVAALAKAGLFYTGI 309

Query: 393 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDA----------- 441
            D VQCF CGG L+ W+  D    +H R FPNC F+     N++S ++            
Sbjct: 310 KDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFL----QNMKSSAEVTPDLQSRGELC 365

Query: 442 ----VSSDRNFPNSTNL-PRNPSMADYEARIF 468
                +S+ N  +S  + P  P MA  EA+ F
Sbjct: 366 ELLETTSESNLEDSIAVGPIVPEMAQGEAQWF 397



 Score = 99.0 bits (245), Expect = 1e-19
 Identities = 83/284 (29%), Positives = 115/284 (40%), Gaps = 57/284 (20%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RLKTF  +   S      +A AGF +TG    ++CF C   +         +  H++
Sbjct: 60  EAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR 119

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             P+C    GF L           I     +V+N L SR                LR G+
Sbjct: 120 FHPDC----GFLLNKDV-----GNIAKYDIRVKN-LKSR----------------LRGGK 153

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAH-LTPRELASAGLYYTGIGDQVQCFCCG 402
           +                EEARL SF+NWP Y   ++P  L+ AG  +TG  D VQCF CG
Sbjct: 154 M------------RYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCG 201

Query: 403 GKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS-SDR 446
           G L NWE  D  W EH + FP C F+  +                ++I  E    S   R
Sbjct: 202 GCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQR 261

Query: 447 NFPNSTNLPRNPSMADYEARIFTFGTWI--YSVNKEQLARAGFY 488
             P ++    +   A  E R+ +F  W    +V    LA+AG +
Sbjct: 262 ELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLF 305



 Score = 69.3 bits (168), Expect = 9e-11
 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 10/138 (7%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRA 414
           N  M SE  RLK+F  +  Y+   P+E+A+AG Y+TG+   +QCFCC   L         
Sbjct: 54  NSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLP 113

Query: 415 WSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSM--ADYEARIFTFGT 472
             +H+R  P+C F+L +++      +    D    N  +  R   M   + EAR+ +F  
Sbjct: 114 IEDHKRFHPDCGFLLNKDV-----GNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRN 168

Query: 473 WIYSVNKEQ---LARAGF 487
           W + V       L+ AGF
Sbjct: 169 WPFYVQGISPCVLSEAGF 186



>gi|19855048|sp|O13816|SCC3_SCHPO   Cohesin subunit psc3 (SCC3 homolog)
          Length = 978

 Score =  118 bits (296), Expect = 1e-25
 Identities = 84/332 (25%), Positives = 137/332 (41%), Gaps = 26/332 (7%)

Query: 921  LFEVVKMGKSAMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVT----------A 970
            LF  +   K     +   W   Y  D   AL +LINF ++C GC   +           +
Sbjct: 87   LFAFLLDQKVDTMDIAVSWFADYAKDNQSALANLINFILKCCGCNRAINVFDVQDQDSAS 146

Query: 971  EMFRHMQNS--------EIIRKMTEEFDEDSGDYPLTMAGPQWKKFKSSFCEFIGVLVRQ 1022
                 +Q S        +I+      F   + DYPL     +++ F+      +   V Q
Sbjct: 147  ATLSQIQLSVERVSAFAKILYLYINNFKTSTRDYPLNSKNLKFRNFRKRLTGLLSNFVSQ 206

Query: 1023 CQY-SIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNT 1081
                + +Y+  + + ++S +  +S S +R  RHT+T+  + +MT L   +  L       
Sbjct: 207  LSIRNYLYNSTVFEDIMSWVVAMSSSTMRPIRHTATVFCLNIMTFLCEKSKELLNEHAIA 266

Query: 1082 QRQYEAE--RNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDXXX 1139
             +Q E E  R+++   R N                QD +   +N  F  VFVHRYRD   
Sbjct: 267  TKQLEKEEKRSRVNRNRINELNNSLGEIVK----QQDTLTTYLNDYFDSVFVHRYRDVEP 322

Query: 1140 XXXXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNKELNS 1199
                        W+      F + SYL+Y+GW + D    VRL  +  L+  +       
Sbjct: 323  KIRVDCLQELGVWINTVPSIFFSGSYLRYLGWMLSDINTTVRLTVVKVLRKFFETDSFIG 382

Query: 1200 KLELFTSRFKDRIVSMT-LDKEYDVAVQAIKL 1230
             L  F+SRFK+RI+ M+ +D +  V V +I+L
Sbjct: 383  GLRHFSSRFKERILEMSCVDADIGVRVASIRL 414



>gi|12585188|sp|Q9JIB3|BIRG_MOUSE   Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis
           inhibitory protein 7)
          Length = 1402

 Score =  117 bits (293), Expect = 3e-25
 Identities = 88/288 (30%), Positives = 127/288 (44%), Gaps = 65/288 (22%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 279
           E  RLKTF ++ +    +   +A AGF +TG    V+CF C   +    +G+S     + 
Sbjct: 60  EAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 339
           RH+K+ P C F+ G  + N            G+Y +           +  P +     +L
Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149

Query: 340 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 398
           R G+               + EEARL+SF++WP YAH T PR L++AG  +TG  D VQC
Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197

Query: 399 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS 443
           F CGG L NWE  D  W EH + FP C F+  +                +++  E    S
Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVKS 257

Query: 444 -SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFY 488
              R  P  +    +   A+ E R+  F  W     V  E L RAGF+
Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFF 305



 Score =  111 bits (278), Expect = 2e-23
 Identities = 74/251 (29%), Positives = 116/251 (46%), Gaps = 35/251 (13%)

Query: 223 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           EE  RL++F ++P      S   L+ AGF++TG+ DTV+CFSC  ++  W+ GD     H
Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217

Query: 282 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 337
            K  P C F+          QS  S  +  QY ++ Y G    + +HF           +
Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQGYEGFVHVTGEHFV--------KSW 258

Query: 338 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 397
           + R   +V    + Y  +    +EE R+  F++WP  + +    L  AG +YTG  D V+
Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVR 314

Query: 398 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 454
           CF CGG L+ W   D    +H + FP C F+      ++S ++ +    S    P +T  
Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370

Query: 455 PRNPSMADYEA 465
            R  +  D  A
Sbjct: 371 TRESNHGDAAA 381



 Score = 72.4 bits (176), Expect = 9e-12
 Identities = 51/154 (33%), Positives = 69/154 (44%), Gaps = 27/154 (17%)

Query: 221 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           F  E  R+  F ++P  SPV    L RAGF YTG+ D VRCFSC   +++W  GD  +  
Sbjct: 275 FANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334

Query: 281 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 335
           H K  P C F+    L++SA               E     +  +AL   +ET     H 
Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHG 377

Query: 336 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQ 369
           D       VVD+      R+ A + +EAR  S Q
Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQ 406



 Score = 64.7 bits (156), Expect = 2e-09
 Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 18/142 (12%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 409
           N  M SE  RLK+F+++  +   TP+E+A+AG Y+TG+   VQCFCC     G  L+   
Sbjct: 54  NSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112

Query: 410 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 468
           P +R    H++  P C F+ G+++ NI      V S    P            + EAR+ 
Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164

Query: 469 TFGTW---IYSVNKEQLARAGF 487
           +F  W    +  +   L+ AGF
Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGF 186



>gi|12643317|sp|Q9R016|BIRE_MOUSE   Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis
           inhibitory protein 5)
          Length = 1403

 Score =  117 bits (293), Expect = 3e-25
 Identities = 89/288 (30%), Positives = 126/288 (43%), Gaps = 65/288 (22%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 279
           E  RLKTF  + +    +   +A AGF +TG    V+CF C   +    +G+S     + 
Sbjct: 60  EAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 339
           RH+K+ P C F+ G  + N            G+Y +           +  P +     +L
Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149

Query: 340 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 398
           R G+               + EEARL+SF++WP YAH T PR L++AG  +TG  D VQC
Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197

Query: 399 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN------IRSESDAVSSD------- 445
           F CGG L NWE  D  W EH + FP C F+  +  +      I+S    V          
Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKS 257

Query: 446 ---RNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFY 488
              R  P  +    +   A+ E R+  F  W     V  E L RAGF+
Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFF 305



 Score =  112 bits (279), Expect = 1e-23
 Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 35/251 (13%)

Query: 223 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           EE  RL++F ++P      S   L+ AGF++TG+ DTV+CFSC  ++  W+ GD     H
Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217

Query: 282 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 337
            K  P C F+          QS  S  +  QY +++Y G    + +HF           +
Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQSYEGFVHVTGEHFV--------KSW 258

Query: 338 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 397
           + R   +V    + Y  +    +EE R+  F++WP  + +    L  AG +YTG  D V+
Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVR 314

Query: 398 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 454
           CF CGG L+ W   D    +H + FP C F+      ++S ++ +    S    P +T  
Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370

Query: 455 PRNPSMADYEA 465
            R  +  D  A
Sbjct: 371 TRESNHGDAAA 381



 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 54/167 (32%), Positives = 74/167 (44%), Gaps = 27/167 (16%)

Query: 221 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           F  E  R+  F ++P  SPV    L RAGF YTG+ D VRCFSC   +++W  GD  +  
Sbjct: 275 FANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334

Query: 281 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 335
           H K  P C F+    L++SA               E     +  +AL   +ET     H 
Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHG 377

Query: 336 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPREL 382
           D       VVD+      R+ A + +EAR  S Q   +Y   T R +
Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQLRDNYTKATFRHM 419



 Score = 64.3 bits (155), Expect = 3e-09
 Identities = 46/142 (32%), Positives = 69/142 (48%), Gaps = 18/142 (12%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 409
           N  M SE  RLK+F+ +  +   TP+E+A+AG Y+TG+   VQCFCC     G  L+   
Sbjct: 54  NSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112

Query: 410 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 468
           P +R    H++  P C F+ G+++ NI      V S    P            + EAR+ 
Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164

Query: 469 TFGTW---IYSVNKEQLARAGF 487
           +F  W    +  +   L+ AGF
Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGF 186



>gi|3914339|sp|O62640|PIAP_PIG   Putative inhibitor of apoptosis
          Length = 358

 Score =  116 bits (291), Expect = 5e-25
 Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 51/206 (24%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E +RL TF  +P  + +S + LA+AGF Y G GD V CF+C   +  W+  D A+  H +
Sbjct: 4   EKDRLLTFQMWPL-TFLSPADLAKAGFYYIGPGDRVACFACGGKLSNWEPKDDAMTEHLR 62

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
             PNC F+ G  L++S+           +Y V N                          
Sbjct: 63  HFPNCPFL-GNQLQDSS-----------RYTVSNL------------------------- 85

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 403
                        +M +  AR K+F NWP    + P +LASAG YY G  D V+CFCC G
Sbjct: 86  -------------SMQTYAARFKTFCNWPSSIPVHPEQLASAGFYYMGHSDDVKCFCCDG 132

Query: 404 KLKNWEPCDRAWSEHRRHFPNCFFVL 429
            L+ WE  D  W EH + FP C +++
Sbjct: 133 GLRCWESGDDPWVEHAKWFPRCEYLI 158



 Score =  114 bits (285), Expect = 3e-24
 Identities = 65/135 (48%), Positives = 74/135 (54%), Gaps = 18/135 (13%)

Query: 358 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 417
           M +E+ RL +FQ WP    L+P +LA AG YY G GD+V CF CGGKL NWEP D A +E
Sbjct: 1   MNTEKDRLLTFQMWP-LTFLSPADLAKAGFYYIGPGDRVACFACGGKLSNWEPKDDAMTE 59

Query: 418 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS- 476
           H RHFPNC F LG  L   S                   N SM  Y AR  TF  W  S 
Sbjct: 60  HLRHFPNCPF-LGNQLQDSSRYTV--------------SNLSMQTYAARFKTFCNWPSSI 104

Query: 477 -VNKEQLARAGFYAL 490
            V+ EQLA AGFY +
Sbjct: 105 PVHPEQLASAGFYYM 119



>gi|12643316|sp|Q9QWK5|BIRA_MOUSE   Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis
           inhibitory protein 1)
          Length = 1403

 Score =  116 bits (290), Expect = 7e-25
 Identities = 87/288 (30%), Positives = 127/288 (44%), Gaps = 65/288 (22%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 279
           E  RLKTF  + +    +   +A AGF +TG    V+CF C   +    +G+S     + 
Sbjct: 60  EAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 339
           RH+K+ P C F+ G  + N            G+Y +           +  P +     +L
Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149

Query: 340 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 398
           R G+               + EEARL+SF++WP YAH T PR L++AG  +TG  D VQC
Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197

Query: 399 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS 443
           F CGG L NWE  D  W EH + FP C F+  +                +++  E    S
Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNS 257

Query: 444 -SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFY 488
              R  P  +    +   A+ E R+ TF  W +   V  + L RAG +
Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLF 305



 Score =  109 bits (272), Expect = 9e-23
 Identities = 68/211 (32%), Positives = 103/211 (48%), Gaps = 28/211 (13%)

Query: 223 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           EE  RL++F ++P      S   L+ AGF++TG+ DTV+CFSC  ++  W+ GD     H
Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217

Query: 282 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 337
            K  P C F+          QS  S  +  QY ++ Y G    + +HF           +
Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQGYEGFVHVTGEHFV--------NSW 258

Query: 338 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 397
           + R   +V    + Y  +    +EE R+ +F++WP  + +    L  AGL+YTG    VQ
Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQ 314

Query: 398 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV 428
           CF CGG ++     D    EH + FPNC F+
Sbjct: 315 CFSCGGCMEKCTEGDDPIQEHNKFFPNCIFL 345



 Score = 66.2 bits (160), Expect = 7e-10
 Identities = 29/71 (40%), Positives = 40/71 (56%)

Query: 221 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           F  E  R+ TF ++P  SPV+   L RAG  YTG+   V+CFSC   +++   GD  +  
Sbjct: 275 FANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFSCGGCMEKCTEGDDPIQE 334

Query: 281 HRKVSPNCRFI 291
           H K  PNC F+
Sbjct: 335 HNKFFPNCIFL 345



 Score = 64.3 bits (155), Expect = 3e-09
 Identities = 46/142 (32%), Positives = 69/142 (48%), Gaps = 18/142 (12%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 409
           N  M SE  RLK+F+ +  +   TP+E+A+AG Y+TG+   VQCFCC     G  L+   
Sbjct: 54  NSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112

Query: 410 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 468
           P +R    H++  P C F+ G+++ NI      V S    P            + EAR+ 
Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164

Query: 469 TFGTW---IYSVNKEQLARAGF 487
           +F  W    +  +   L+ AGF
Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGF 186



>gi|12643314|sp|Q9JIB6|BIRF_MOUSE   Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis
           inhibitory protein 6)
          Length = 1403

 Score =  116 bits (290), Expect = 7e-25
 Identities = 90/295 (30%), Positives = 133/295 (45%), Gaps = 73/295 (24%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 279
           E  RLKTF ++ +    +   +A AGF +TG    V+CF C   +    +G+S     + 
Sbjct: 60  EAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115

Query: 280 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 339
           RH+K+ P C F+ G  + N            G+Y +           +  P +     +L
Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149

Query: 340 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 398
           R G+               + EEARL+SF++WP YAH T PR L++AG  +TG  D VQC
Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQC 197

Query: 399 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNP 458
           F CGG L NWE  D  W EH + FP C F     L  +  S+ ++               
Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEF-----LQSKKSSEEIAQ-------------- 238

Query: 459 SMADYEARIFTFGT-WIYSVNKEQLARAGFYALDDTIFQNPMVQEAIRMGFSFKD 512
            + DYE  +   G  ++ S  + +L     Y  +D++F N    E +RM   FKD
Sbjct: 239 YIQDYEGFVHVTGEHFVKSWVRRELPMVSAYC-NDSVFTN----EELRMDM-FKD 287



 Score =  110 bits (276), Expect = 3e-23
 Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 35/251 (13%)

Query: 223 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           EE  RL++F ++P      S   L+ AGF++TG+ DTV+CFSC  ++  W+ GD     H
Sbjct: 158 EEEARLESFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217

Query: 282 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 337
            K  P C F+          QS  S  +  QY +++Y G    + +HF           +
Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQDYEGFVHVTGEHFV--------KSW 258

Query: 338 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 397
           + R   +V    + Y  +    +EE R+  F++WP  + +    L  AG +YTG  D V+
Sbjct: 259 VRRELPMV----SAYCNDSVFTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVR 314

Query: 398 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 454
           CF CGG L+ W   D    +H + FP C F+      ++S ++ +    S    P +T  
Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370

Query: 455 PRNPSMADYEA 465
            R  +  D  A
Sbjct: 371 TRESNHDDAAA 381



 Score = 70.9 bits (172), Expect = 3e-11
 Identities = 51/154 (33%), Positives = 69/154 (44%), Gaps = 27/154 (17%)

Query: 221 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           F  E  R+  F ++P  SPV    L RAGF YTG+ D VRCFSC   +++W  GD  +  
Sbjct: 275 FTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334

Query: 281 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 335
           H K  P C F+    L++SA               E     +  +AL   +ET     H 
Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHD 377

Query: 336 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQ 369
           D       VVD+      R+ A + +EAR  S Q
Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQ 406



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 46/142 (32%), Positives = 70/142 (49%), Gaps = 18/142 (12%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 409
           N  M SE  RLK+F+++  +   TP+E+A+AG Y+TG+   VQCFCC     G  L+   
Sbjct: 54  NSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112

Query: 410 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 468
           P +R    H++  P C F+ G+++ NI      V S    P            + EAR+ 
Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164

Query: 469 TFGTW---IYSVNKEQLARAGF 487
           +F  W    +  +   L+ AGF
Sbjct: 165 SFEDWPFYAHGTSPRALSAAGF 186



>gi|1170471|sp|P41437|IAP3_NPVOP   Apoptosis inhibitor 3 (IAP-3)
          Length = 268

 Score =  115 bits (289), Expect = 8e-25
 Identities = 69/218 (31%), Positives = 96/218 (44%), Gaps = 47/218 (21%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           RL T+ N+P    +  S +A +GF Y G GD VRC  C   +  W  GD     H++ +P
Sbjct: 21  RLGTYTNWPV-QFLEPSRMAASGFYYLGRGDEVRCAFCKVEITNWVRGDDPETDHKRWAP 79

Query: 287 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 346
            C F+      N+A  + +                 D     R +  H  Y         
Sbjct: 80  QCPFV-----RNNAHDTPH-----------------DRAPPARSAAAHPQYA-------- 109

Query: 347 ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLK 406
                        +E ARL++F  WP      P ELA AG +YTG GD+ +CFCC G LK
Sbjct: 110 -------------TEAARLRTFAEWPRGLKQRPEELAEAGFFYTGQGDKTRCFCCDGGLK 156

Query: 407 NWEPCDRAWSEHRRHFPNCFFVL---GRNLNIRSESDA 441
           +WEP D  W +H R +  C +VL   GR+   R  ++A
Sbjct: 157 DWEPDDAPWQQHARWYDRCEYVLLVKGRDFVQRVMTEA 194



 Score = 72.8 bits (177), Expect = 7e-12
 Identities = 44/133 (33%), Positives = 68/133 (51%), Gaps = 11/133 (8%)

Query: 358 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 417
           M ++ ARL ++ NWP    L P  +A++G YY G GD+V+C  C  ++ NW   D   ++
Sbjct: 15  MKNKAARLGTYTNWP-VQFLEPSRMAASGFYYLGRGDEVRCAFCKVEITNWVRGDDPETD 73

Query: 418 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV 477
           H+R  P C FV       R+ +     D   P + +   +P  A   AR+ TF  W   +
Sbjct: 74  HKRWAPQCPFV-------RNNAHDTPHD-RAPPARSAAAHPQYATEAARLRTFAEWPRGL 125

Query: 478 NK--EQLARAGFY 488
            +  E+LA AGF+
Sbjct: 126 KQRPEELAEAGFF 138



 Score = 62.8 bits (151), Expect = 8e-09
 Identities = 26/72 (36%), Positives = 38/72 (52%)

Query: 220 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 279
           ++  E  RL+TFA +P G       LA AGF YTG+GD  RCF C   +  W+  D+   
Sbjct: 107 QYATEAARLRTFAEWPRGLKQRPEELAEAGFFYTGQGDKTRCFCCDGGLKDWEPDDAPWQ 166

Query: 280 RHRKVSPNCRFI 291
           +H +    C ++
Sbjct: 167 QHARWYDRCEYV 178



>gi|12643315|sp|Q9QUK4|BIRB_MOUSE   Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis
           inhibitory protein 2)
          Length = 1447

 Score =  113 bits (282), Expect = 5e-24
 Identities = 70/211 (33%), Positives = 104/211 (49%), Gaps = 28/211 (13%)

Query: 223 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           EE  RL++F ++P      S   L+ AGF++TG+ DTV+CFSC   +  W+ GD     H
Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEH 217

Query: 282 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 337
            K  P C F+          QS  S  +  QY V++Y G    + +HF           +
Sbjct: 218 AKWFPKCEFL----------QSKKSPEEITQY-VQSYEGFLHVTGEHFV--------NSW 258

Query: 338 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 397
           + R   +V    + Y  +    +EE R+ +F++WP  +      L  AGL+YTG  D VQ
Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQ 314

Query: 398 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV 428
           CF CGG ++ W   D    +H + FPNC F+
Sbjct: 315 CFSCGGCMEKWAEGDNPIEDHTKFFPNCVFL 345



 Score =  107 bits (268), Expect = 2e-22
 Identities = 83/284 (29%), Positives = 120/284 (42%), Gaps = 57/284 (20%)

Query: 224 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 283
           E  RLKTF  +      +   +A AGF +TG    V+CF C   +   +     +  H+K
Sbjct: 60  EAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKK 119

Query: 284 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 343
           + P C F+ G  + N            G+Y +           +  P +     +LR  +
Sbjct: 120 LRPECEFLLGKDVGNI-----------GKYDIR----------VKSPEK-----MLRGDK 153

Query: 344 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQCFCCG 402
                          + EEARL+SF++WP YAH T PR L++AG  +TG  D VQCF CG
Sbjct: 154 A------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCG 201

Query: 403 GKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS-SDR 446
           G L NWE  D  W EH + FP C F+  +                L++  E    S   R
Sbjct: 202 GCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRR 261

Query: 447 NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNK--EQLARAGFY 488
             P  +    +   A+ E R+ TF  W +      E L +AG +
Sbjct: 262 ELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLF 305



 Score = 69.7 bits (169), Expect = 8e-11
 Identities = 29/71 (40%), Positives = 42/71 (59%)

Query: 221 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           F  E  R+ TF ++P  SP +   L +AG  YTG+ D V+CFSC   +++W  GD+ +  
Sbjct: 275 FANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGCMEKWAEGDNPIED 334

Query: 281 HRKVSPNCRFI 291
           H K  PNC F+
Sbjct: 335 HTKFFPNCVFL 345



 Score = 66.2 bits (160), Expect = 8e-10
 Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 8/137 (5%)

Query: 355 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRA 414
           N  M SE  RLK+F+ +  +   TP+E+A+AG Y+TG+   VQCFCC   L +       
Sbjct: 54  NSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLP 113

Query: 415 WSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTW 473
              H++  P C F+LG+++ NI      V S    P            + EAR+ +F  W
Sbjct: 114 IENHKKLRPECEFLLGKDVGNIGKYDIRVKS----PEKMLRGDKARYHEEEARLESFEDW 169

Query: 474 ---IYSVNKEQLARAGF 487
               +  +   L+ AGF
Sbjct: 170 PFYAHGTSPRVLSAAGF 186



>gi|2497243|sp|Q24306|IAP1_DROME   Apoptosis 1 inhibitor (Inhibitor of apoptosis 1) (dIAP1) (Thread
           protein)
          Length = 438

 Score =  111 bits (278), Expect = 2e-23
 Identities = 85/291 (29%), Positives = 122/291 (41%), Gaps = 56/291 (19%)

Query: 184 PGAVEKVDKSYFQEKMTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSAS 243
           P A ++VD +    ++  N+   ++     D+N+EE       RLKTF ++P    +   
Sbjct: 13  PIAFDQVDNNTNATQLFKNNINKTRM---NDLNREE------TRLKTFTDWPL-DWLDKR 62

Query: 244 TLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRF----------ING 293
            LA+ G  +T  GD V+CF C   +  W+  D  V  H++ SPNC            IN 
Sbjct: 63  QLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINA 122

Query: 294 FYLEN----------SATQST---------------NSGIQNGQYKVENYLGSRDHFALD 328
             L+            A  ST               +  IQ+      N  GS    A  
Sbjct: 123 EALDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIGMNAVNAAGSVTGTAAP 182

Query: 329 RPS---ETHA--------DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHL 377
           +P     THA        D    T +    S   +P+ P    E ARL++F+ WP     
Sbjct: 183 QPRVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIETARLRTFEAWPRNLKQ 242

Query: 378 TPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV 428
            P +LA AG +YTG+GD+V+CF CGG L +W   D  W +H      C FV
Sbjct: 243 KPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFV 293



 Score = 70.1 bits (170), Expect = 5e-11
 Identities = 38/90 (42%), Positives = 53/90 (58%), Gaps = 4/90 (4%)

Query: 361 EEARLKSFQNWP-DYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHR 419
           EE RLK+F +WP D+  L  R+LA  G+Y+T  GD+V+CF CG ++  WE  D+   EH+
Sbjct: 44  EETRLKTFTDWPLDW--LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQ 101

Query: 420 RHFPNCFFVLGRNLNIRSESDAVSSDRNFP 449
           R  PNC  +  R  N     +A + DR  P
Sbjct: 102 RWSPNCPLLRRRTTN-NVPINAEALDRILP 130



>gi|731791|sp|P40541|SCC3_YEAST   Cohesin subunit SCC3 (Irregular cell behavior protein 1)
          Length = 1150

 Score = 85.9 bits (211), Expect = 9e-16
 Identities = 85/341 (24%), Positives = 148/341 (43%), Gaps = 31/341 (9%)

Query: 921  LFEVVKMGKS-AMQSVVDDWIESYKHDRDIALLDLINFFIQCSGCKGVVT-AEMFRHMQN 978
            LF+++   +  +++ ++ +W+E+Y  +RD  L + IN  + C G    V   ++  +  +
Sbjct: 137  LFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESS 196

Query: 979  SEIIRKMTEEFDEDSGDYPLTMAGPQWKKFKS--------SFCEFIGVLVRQCQ-YSIIY 1029
            +E I ++   F          +   + KK K+        +F EF+  L+       ++Y
Sbjct: 197  NETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLY 256

Query: 1030 DEYMMDT--------VISLLTGLSD---SQVRAFRHTSTLAAMKLMTALVNVALNLSIN- 1077
             E   D         V+ LLT LS     ++R FR+ STL        L   A+NL  N 
Sbjct: 257  VESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNY 316

Query: 1078 MDNTQRQYEAERNKMIGKRANXXXXXXXXXXXXXXXNQDEIENMMNAIFKGVFVHRYRDX 1137
            +    +Q   E  K   +  N               ++  I+++++ I K  FVHRY+D 
Sbjct: 317  LAKLSKQLSLEEKKK--RPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDV 374

Query: 1138 XXXXXXXXXXXXXXWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLY---YN 1194
                          W+K Y + FL  ++LKY GW + D    VRL+    L  L    +N
Sbjct: 375  SDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHN 434

Query: 1195 KEL--NSKLELFTSRFKDRIVSMTL-DKEYDVAVQAIKLLT 1232
             +   NS +     RFK +I+ + + D   DV + +I++LT
Sbjct: 435  SKSTDNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQVLT 475



>gi|21759008|sp|Q96CA5|BIR7_HUMAN   Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of
           apoptosis protein) (KIAP) (Melanoma inhibitor of
           apoptosis protein) (ML-IAP) (Livin)
          Length = 298

 Score = 84.3 bits (207), Expect = 2e-15
 Identities = 37/77 (48%), Positives = 51/77 (66%)

Query: 353 PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCD 412
           P  P M SEE RL SF +WP  A + P  LA+AG ++TG  D+V+CF C G L++W+  D
Sbjct: 79  PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138

Query: 413 RAWSEHRRHFPNCFFVL 429
             W+EH + FP+C F+L
Sbjct: 139 DPWTEHAKWFPSCQFLL 155



 Score = 60.5 bits (145), Expect = 4e-08
 Identities = 26/65 (40%), Positives = 37/65 (56%)

Query: 227 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 286
           RL +F ++P  + V    LA AGF +TG  D VRCF C+  +  W+ GD     H K  P
Sbjct: 90  RLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFP 149

Query: 287 NCRFI 291
           +C+F+
Sbjct: 150 SCQFL 154



>gi|2497245|sp|O10296|IAP1_NPVOP   Apoptosis inhibitor 1 (IAP-1)
          Length = 275

 Score = 78.6 bits (192), Expect = 1e-13
 Identities = 50/216 (23%), Positives = 87/216 (40%), Gaps = 35/216 (16%)

Query: 214 DINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQY 273
           + + E  F     R  +F ++P  +    ++L   GF YT   D V C  C   +  W+ 
Sbjct: 14  ETSAERVFGMLIERHNSFEDYPIDNDAFVNSLIVNGFRYTHVDDAVVCEYCGVVIKNWRE 73

Query: 274 GDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET 333
            D     H  +SP C +                          N +   + FA D  ++ 
Sbjct: 74  NDVVEFVHATLSPYCVY-------------------------ANKIAQNEQFAEDISTDA 108

Query: 334 HADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIG 393
               ++  G+       +Y R   +    AR  +F +WP   +    ++A AG+++T +G
Sbjct: 109 ---VVVSPGK----PRCVYNR---LAHPSARRATFDHWPAALNALTHDIAEAGMFHTMLG 158

Query: 394 DQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVL 429
           D+  CF C  ++++W P D  W  H    P C+FV+
Sbjct: 159 DETACFFCDCRVRDWLPGDDPWQRHALANPQCYFVV 194



 Score = 38.5 bits (88), Expect = 0.16
 Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 12/132 (9%)

Query: 364 RLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFP 423
           R  SF+++P         L   G  YT + D V C  CG  +KNW   D     H    P
Sbjct: 27  RHNSFEDYPIDNDAFVNSLIVNGFRYTHVDDAVVCEYCGVVIKNWRENDVVEFVHATLSP 86

Query: 424 NCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNP-----SMADYEARIFTFGTWIYSVN 478
            C +      N  ++++  + D +       P  P      +A   AR  TF  W  ++N
Sbjct: 87  YCVYA-----NKIAQNEQFAEDISTDAVVVSPGKPRCVYNRLAHPSARRATFDHWPAALN 141

Query: 479 --KEQLARAGFY 488
                +A AG +
Sbjct: 142 ALTHDIAEAGMF 153



>gi|12585192|sp|Q9NR09|BIR6_HUMAN   Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating
           BIR-domain enzyme apollon)
          Length = 4829

 Score = 75.1 bits (183), Expect = 2e-12
 Identities = 45/123 (36%), Positives = 57/123 (46%), Gaps = 20/123 (16%)

Query: 358 MYSEEARLKSFQNWPD--YAHLTPRELASAGLYY---TGIGDQVQCFCCGGKLKNWEPCD 412
           MYSE  R ++F +WP   Y    P  +A AG Y+   +   D+  CF C   L  WEP D
Sbjct: 255 MYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTD 314

Query: 413 RAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSM---ADYEARIFT 469
             WSEH RH PNC FV G +             +N P S  L  +P+     D   RI  
Sbjct: 315 EPWSEHERHSPNCPFVKGEH------------TQNVPLSVTLATSPAQFPCTDGTDRISC 362

Query: 470 FGT 472
           FG+
Sbjct: 363 FGS 365



 Score = 44.3 bits (103), Expect = 0.003
 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 224 EFNRLKTFANFPSGSP--VSASTLARAGFLY---TGEGDTVRCFSCHAAVDRWQYGDSAV 278
           E NR +TF ++P           +A+AGF +   +   D   CF+C   +  W+  D   
Sbjct: 258 EANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPW 317

Query: 279 GRHRKVSPNCRFINGFYLEN 298
             H + SPNC F+ G + +N
Sbjct: 318 SEHERHSPNCPFVKGEHTQN 337



>gi|33302608|sp|P47732|ZFP_IRV6   Zinc finger protein
          Length = 208

 Score = 72.4 bits (176), Expect = 1e-11
 Identities = 35/79 (44%), Positives = 44/79 (55%), Gaps = 4/79 (5%)

Query: 354 RNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDR 413
           +N    S + RL SFQNWP     +  +L+ AG  Y  IGDQVQCF C  KLK W+  D 
Sbjct: 30  KNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRSDN 89

Query: 414 AWSEHRRHFP----NCFFV 428
            + EH++H      NC FV
Sbjct: 90  PFEEHKKHTQDLKINCLFV 108



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 4/100 (4%)

Query: 215 INKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYG 274
           I K   F     RL +F N+P     S   L+RAGF+Y   GD V+CF C   +  W+  
Sbjct: 28  IIKNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRS 87

Query: 275 DSAVGRHRK----VSPNCRFINGFYLENSATQSTNSGIQN 310
           D+    H+K    +  NC F+     +N     + S  QN
Sbjct: 88  DNPFEEHKKHTQDLKINCLFVKSIEFDNFVKNHSESCFQN 127



>gi|1170468|sp|P41435|IAP1_NPVAC   Apoptosis inhibitor 1 (IAP-1)
          Length = 286

 Score = 70.9 bits (172), Expect = 3e-11
 Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 36/217 (16%)

Query: 214 DINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQY 273
           D   E  F     R  +F N+P  +    ++L   GF Y    D V C  C A +  W  
Sbjct: 19  DNTAEHVFDMLIERHSSFENYPIENTAFINSLIVNGFKYNQVDDHVVCEYCEAEIKNWSE 78

Query: 274 GDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET 333
            +     H  +SP C +                          N +  R+ F     + T
Sbjct: 79  DECIEYAHVTLSPYCAY-------------------------ANKIAERESFG---DNIT 110

Query: 334 HADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQN-WPDYAHLTPRELASAGLYYTGI 392
               L++ G+       +Y     M + ++R+ +F N WP         +A AGL+YTG 
Sbjct: 111 INAVLVKEGK----PKCVYR---CMSNLQSRMDTFVNFWPAALRDMITNIAEAGLFYTGR 163

Query: 393 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVL 429
           GD+  CF C   +++W   +  W  H    P C+FVL
Sbjct: 164 GDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFVL 200



 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 10/113 (8%)

Query: 183 CPGAVEKVDKSYFQEKMTFNSF---EGSKTCVPADINKEEEFVEEFNRLKTFANF-PSGS 238
           C  A +  ++  F + +T N+    EG   CV   ++  +      +R+ TF NF P+  
Sbjct: 93  CAYANKIAERESFGDNITINAVLVKEGKPKCVYRCMSNLQ------SRMDTFVNFWPAAL 146

Query: 239 PVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 291
               + +A AG  YTG GD   CF C   V  W   +    RH   +P C F+
Sbjct: 147 RDMITNIAEAGLFYTGRGDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFV 199



>gi|12585184|sp|Q9JHY7|BIR5_RAT   Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor
           survivin)
          Length = 142

 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 5/76 (6%)

Query: 358 MYSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCD 412
           MY ++ R+ +F+NWP  +    TP  +A AG  +       D  QCF C  +L+ WEP D
Sbjct: 12  MYLKDHRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDD 71

Query: 413 RAWSEHRRHFPNCFFV 428
               EHR+H P C F+
Sbjct: 72  NPIEEHRKHSPGCAFL 87



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 5/71 (7%)

Query: 226 NRLKTFANFPSGSPVSAST--LARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           +R+ TF N+P     S +   +A AGF++     E D  +CF C   ++ W+  D+ +  
Sbjct: 17  HRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEE 76

Query: 281 HRKVSPNCRFI 291
           HRK SP C F+
Sbjct: 77  HRKHSPGCAFL 87



>gi|6647548|sp|O70201|BIR5_MOUSE   Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor
           survivin) (Apoptosis inhibitor 4) (TIAP)
          Length = 140

 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 5/81 (6%)

Query: 353 PRNPAMYSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKN 407
           P+   +Y +  R+ +F+NWP  +    TP  +A AG  +       D  QCF C  +L+ 
Sbjct: 7   PQIWQLYLKNYRIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEG 66

Query: 408 WEPCDRAWSEHRRHFPNCFFV 428
           WEP D    EHR+H P C F+
Sbjct: 67  WEPDDNPIEEHRKHSPGCAFL 87



 Score = 45.8 bits (107), Expect = 0.001
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)

Query: 227 RLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGRH 281
           R+ TF N+P       +   +A AGF++     E D  +CF C   ++ W+  D+ +  H
Sbjct: 18  RIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEH 77

Query: 282 RKVSPNCRFI 291
           RK SP C F+
Sbjct: 78  RKHSPGCAFL 87



>gi|3183409|sp|O14064|BIR1_SCHPO   Bir1 protein (Chromosome segregation protein cut17)
          Length = 997

 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 52/221 (23%), Positives = 78/221 (35%), Gaps = 59/221 (26%)

Query: 227 RLKTF--ANFPSGSPVSASTLARAGFLYTGEG--------DTVRCFSCHAAVDRWQYGDS 276
           RL TF    +P   P +  TLA  GF Y            D V C+ C  +   W+  D 
Sbjct: 25  RLDTFQKKKWPRAKP-TPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYDWEDDDD 83

Query: 277 AVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHAD 336
            +  H   SP+C +      +N+  Q+  +                   AL +  E    
Sbjct: 84  PLKEHITHSPSCPWAYILSSKNNPNQNPQAA------------------ALTKCREQ--- 122

Query: 337 YLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQ- 395
                       D ++P              + N PDY H  P  +A++G  Y    D  
Sbjct: 123 ---------TFVDKVWP--------------YTNRPDY-HCEPSVMAASGFVYNPTADAK 158

Query: 396 --VQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN 434
               C  C   L +WEP D  ++EH+R   +C F   ++ N
Sbjct: 159 DAAHCLYCDINLHDWEPDDDPYTEHKRRRADCVFFTWKDPN 199



 Score = 46.2 bits (108), Expect = 8e-04
 Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 25/129 (19%)

Query: 358 MYSEEARLKSFQN--WPDYAHLTPRELASAGLYYTGIG--------DQVQCFCCGGKLKN 407
           M +   RL +FQ   WP  A  TP  LA+ G YY  I         D V C+ C     +
Sbjct: 19  MCNYSKRLDTFQKKKWPR-AKPTPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYD 77

Query: 408 WEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARI 467
           WE  D    EH  H P+C +              + S +N PN    P+  ++     + 
Sbjct: 78  WEDDDDPLKEHITHSPSCPWAY------------ILSSKNNPNQN--PQAAALTKCREQT 123

Query: 468 FTFGTWIYS 476
           F    W Y+
Sbjct: 124 FVDKVWPYT 132



>gi|6647543|sp|O15392|BIR5_HUMAN   Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor
           survivin) (Apoptosis inhibitor 4)
          Length = 142

 Score = 50.8 bits (120), Expect = 3e-05
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 5/75 (6%)

Query: 359 YSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCDR 413
           + ++ R+ +F+NWP  +    TP  +A AG  +       D  QCF C  +L+ WEP D 
Sbjct: 13  FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDD 72

Query: 414 AWSEHRRHFPNCFFV 428
              EH++H   C F+
Sbjct: 73  PIEEHKKHSSGCAFL 87



 Score = 44.7 bits (104), Expect = 0.003
 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%)

Query: 226 NRLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 280
           +R+ TF N+P   G   +   +A AGF++     E D  +CF C   ++ W+  D  +  
Sbjct: 17  HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEE 76

Query: 281 HRKVSPNCRFIN 292
           H+K S  C F++
Sbjct: 77  HKKHSSGCAFLS 88



>gi|1170469|sp|P41454|IAP2_NPVAC   Probable apoptosis inhibitor 2 (IAP-2)
          Length = 249

 Score = 43.5 bits (101), Expect = 0.006
 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 10/76 (13%)

Query: 224 EFNRLKTFANFPSG------SPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSA 277
           E  R K+F +F S         V    LAR GF Y G+   +RC  CH  V +++  D A
Sbjct: 82  ESMRKKSFTSFKSSRRQFASQSVVVDMLARRGFYYFGKAGHLRCSGCH-IVFKYKSVDDA 140

Query: 278 VGRHRKVSPNCRFING 293
             RH++   NC+F+N 
Sbjct: 141 QRRHKQ---NCKFLNA 153



>gi|1705854|sp|Q00975|CCAB_HUMAN   Voltage-dependent N-type calcium channel alpha-1B subunit (Calcium
            channel, L type, alpha-1 polypeptide isoform 5) (Brain
            calcium channel III) (BIII)
          Length = 2339

 Score = 41.6 bits (96), Expect = 0.020
 Identities = 48/173 (27%), Positives = 69/173 (39%), Gaps = 25/173 (14%)

Query: 552  QTSLQKGKSGALEGIGPPRVFLPRVKSSWRSKRLARGGGARGTSPGANPASLWIPTAQGS 611
            + +L++ +   L G    RVFL R KSS     L+ GG  +    G   +  W       
Sbjct: 1894 KATLEQTQPAVLRG---ARVFL-RQKSS---TSLSNGGAIQNQESGIKESVSWGTQRTQD 1946

Query: 612  AGHSYRPPLDTPLKTEEPRLDRVRGGSAAKRMKFEGVKKRKGKNILYQPRGEEAPGLRKK 671
            A H  RPPL+    TE P     R G+ A  ++ + + +R        P GE  PGL   
Sbjct: 1947 APHEARPPLERGHSTEIP---VGRSGALAVDVQMQSITRRG-------PDGEPQPGL--- 1993

Query: 672  EEWGRRTVSLLPLCTLRGEGSSFRLP---SLKIFSSFPRPTLPRGLYGDPPPP 721
            E  GR   + +P      +  +   P   S+   +  PR T       D PPP
Sbjct: 1994 ESQGR--AASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPP 2044



>gi|32129904|sp|Q93WF1|PL20_ARATH   Probable pectate lyase 20 precursor
          Length = 417

 Score = 40.0 bits (92), Expect = 0.055
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 366 KSFQNWPDYAHLTPRELASA---GLYYTGIGDQVQCFCC--GGKLKNWEPCDRAWSEHRR 420
           +S + W ++A   P E+A+     +  +    ++  F C  G  + +   CDR W   R+
Sbjct: 27  RSNETWHEHAVENPEEVAAMVDMSIRNSTARRRLGYFSCSTGNPIDDCWRCDRRWQSRRK 86

Query: 421 HFPNCFFVLGRN-LNIRSESDAVSSDRNFPNSTNLPRNP 458
           H  NC    GRN +  R     V SD   PN  N P NP
Sbjct: 87  HLANCAIGFGRNAIGGRDGRYYVVSD---PNDDN-PVNP 121



>gi|2497248|sp|O11451|IAPL_ASFC3   IAP-like protein p27
          Length = 224

 Score = 36.6 bits (83), Expect = 0.57
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 351 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 408
           + P+     S +AR +SF   +  DY      + ++AGL+YT    ++ C+CCG K  NW
Sbjct: 19  VKPKYVGYSSVDARNQSFAIHDIKDY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 72



>gi|2497250|sp|O11453|IAPL_ASFM2   IAP-like protein p27
          Length = 238

 Score = 36.2 bits (82), Expect = 0.83
 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 351 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 408
           + P+     S +AR KSF   +  +Y      + ++AGL+YT    ++ C+CCG K  NW
Sbjct: 33  VKPKYVGYSSVDARNKSFAIHDIKNY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 86



>gi|3915379|sp|O25505|ENGA_HELPY   GTP-binding protein engA
          Length = 458

 Score = 35.8 bits (81), Expect = 0.98
 Identities = 22/83 (26%), Positives = 43/83 (51%), Gaps = 4/83 (4%)

Query: 1425 LPQYFDLEIYTTGRLEKHLDALLR--QIRNIVEKHTDTDVLEACSKTYHALCNE--EFTI 1480
            +P+ F++ +     +   +DA+L    +  I+E+  D D+LE+     +AL  E  +  I
Sbjct: 142  MPKSFNISVSHNRGISALIDAVLSALDLNQIIEQDLDADILESLETPNNALEEEIIQVGI 201

Query: 1481 FNRVDISRSQLIDELADKFNRLL 1503
              RV++ +S L++ L  K   L+
Sbjct: 202  IGRVNVGKSSLLNALTKKERSLV 224



>gi|2497247|sp|O12407|IAPL_ASFCH   IAP-like protein p27
          Length = 224

 Score = 35.0 bits (79), Expect = 2.1
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 351 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 408
           + P+     S +AR +SF   +  +Y      + ++AGL+YT    ++ C+CCG K  NW
Sbjct: 19  VKPKYVGYSSVDARNQSFAIHDIKNY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 72



>gi|2497249|sp|O11452|IAPL_ASFM1   IAP-like protein p27
          Length = 224

 Score = 35.0 bits (79), Expect = 2.1
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 8/60 (13%)

Query: 351 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 408
           + P+     S +AR +SF   +  +Y      + ++AGL+YT    ++ C+CCG K  NW
Sbjct: 19  VKPKYVGYSSVDARNQSFAIHDIKNY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 72






  Database: Non-redundant SwissProt sequences
    Posted date:  Mar 9, 2004  2:01 PM
  Number of letters in database: 53,526,777
  Number of sequences in database:  145,815
  
Lambda     K      H
   0.318    0.134    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,779,919
Number of Sequences: 145815
Number of extensions: 821699
Number of successful extensions: 2064
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2026
Number of HSP's gapped (non-prelim): 27
length of query: 1989
length of database: 53,526,777
effective HSP length: 125
effective length of query: 1864
effective length of database: 35,299,902
effective search space: 65799017328
effective search space used: 65799017328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 73 (32.7 bits)







 


 
Format
  


 


 
Show
  Graphical OverviewLinkoutSequence RetrievalNCBI-giAlignmentPSSMBioseq in HTMLPlain textASN.1XMLformat


 


 
Use new formatter
  Masking CharacterDefault(X for protein, n for nucleotide)Lower Case
Masking ColorBlackGreyRed



 


 
Number of:
  Descriptions01050100
Alignments01050100



 


 
Alignment view
  PairwisePairwise with identitiesquery-anchored with identitiesquery-anchored without identitiesflat query-anchored with identitiesflat query-anchored without identitiesHit Table


 


 
Format for PSI-BLAST
  with inclusion threshold:


 


 
Limit results by entrez query
   or select from:All organismsViruses [ORGN]Archaea [ORGN]Bacteria [ORGN]Eukaryota [ORGN]Viridiplantae [ORGN]Fungi [ORGN]Metazoa [ORGN]Arthropoda [ORGN]Vertebrata [ORGN]Mammalia [ORGN]Rodentia [ORGN]Primates [ORGN]-------------------Aeropyrum pernix [ORGN]Aquifex aeolicus [ORGN]Arabidopsis thaliana [ORGN]Bacillus subtilis [ORGN]Bos taurus [ORGN]Caenorhabditis elegans [ORGN]Canis familiaris[ORGN]Danio rerio [ORGN]Dictyostelium discoideum [ORGN]Drosophila melanogaster [ORGN]Escherichia coli [ORGN]Gallus gallus [ORGN]Homo sapiens [ORGN]Human immunodeficiency virus type 1 [ORGN]Methanococcus jannaschii [ORGN]Mus musculus [ORGN]Oryctolagus cuniculus [ORGN]Oryza sativa [ORGN]Ovis aries [ORGN]Plasmodium falciparum [ORGN]Rattus norvegicus [ORGN]Saccharomyces cerevisiae [ORGN]Schizosaccharomyces pombe [ORGN]Xenopus tropicalis[ORGN]Simian immunodeficiency virus [ORGN]Sus scrofa[ORGN]Synechocystis PCC6803 [ORGN]Takifugu rubripes [ORGN]Xenopus laevis [ORGN]Zea mays [ORGN]


 


 
Expect value range:
    







 or