BLASTP 2.2.8 [Jan-05-2004]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. RID: 1079342903-3246-188845090602.BLASTQ3 Query= hg16_dna_2|geneid_v1.1_predicted_protein_2|602_AA (601 letters) Database: Non-redundant SwissProt sequences 145,815 sequences; 53,526,777 total letters If you have any problems or questions with the results of this search please refer to the BLAST FAQs Taxonomy reports
RID: 1079342903-3246-188845090602.BLASTQ3
Query= hg16_dna_2|geneid_v1.1_predicted_protein_2|602_AA (601 letters)
Database: Non-redundant SwissProt sequences 145,815 sequences; 53,526,777 total letters
If you have any problems or questions with the results of this search please refer to the BLAST FAQs
Taxonomy reports
Score E Sequences producing significant alignments: (bits) Value gi|12643387|sp|P98170|BIR4_HUMAN Baculoviral IAP repeat-con... 1038 0.0 gi|12585185|sp|Q9R0I6|BIR4_RAT Baculoviral IAP repeat-conta... 938 0.0 gi|2497241|sp|Q60989|BIR4_MOUSE Baculoviral IAP repeat-cont... 924 0.0 gi|21759007|sp|Q95M72|BIR8_PANTR Baculoviral IAP repeat-con... 402 e-112 gi|21759006|sp|Q95M71|BIR8_GORGO Baculoviral IAP repeat-con... 401 e-111 gi|21759009|sp|Q96P09|BIR8_HUMAN Baculoviral IAP repeat-con... 401 e-111 gi|2497238|sp|Q13490|BIR2_HUMAN Baculoviral IAP repeat-cont... 283 6e-76 gi|2497239|sp|Q62210|BIR2_MOUSE Baculoviral IAP repeat-cont... 278 2e-74 gi|2497236|sp|Q13489|BIR3_HUMAN Baculoviral IAP repeat-cont... 271 2e-72 gi|2497237|sp|O08863|BIR3_MOUSE Baculoviral IAP repeat-cont... 264 4e-70 gi|2497240|sp|Q90660|BIR_CHICK Inhibitor of apoptosis prote... 263 9e-70 gi|2497244|sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhi... 234 4e-61 gi|3914339|sp|O62640|PIAP_PIG Putative inhibitor of apoptosis 232 2e-60 gi|12643317|sp|Q9R016|BIRE_MOUSE Baculoviral IAP repeat-con... 163 1e-39 gi|12585188|sp|Q9JIB3|BIRG_MOUSE Baculoviral IAP repeat-con... 163 1e-39 gi|12643314|sp|Q9JIB6|BIRF_MOUSE Baculoviral IAP repeat-con... 162 3e-39 gi|12643316|sp|Q9QWK5|BIRA_MOUSE Baculoviral IAP repeat-con... 154 6e-37 gi|12643315|sp|Q9QUK4|BIRB_MOUSE Baculoviral IAP repeat-con... 150 7e-36 gi|1170471|sp|P41437|IAP3_NPVOP Apoptosis inhibitor 3 (IAP-3) 145 2e-34 gi|12643291|sp|Q13075|BIR1_HUMAN Baculoviral IAP repeat-con... 144 6e-34 gi|1170470|sp|P41436|IAP_GVCP Apoptosis inhibitor IAP 131 4e-30 gi|2497243|sp|Q24306|IAP1_DROME Apoptosis 1 inhibitor (Inhi... 128 5e-29 gi|21759008|sp|Q96CA5|BIR7_HUMAN Baculoviral IAP repeat-con... 99 4e-20 gi|33302608|sp|P47732|ZFP_IRV6 Zinc finger protein 78 5e-14 gi|2497245|sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 (IAP-1) 77 9e-14 gi|12585192|sp|Q9NR09|BIR6_HUMAN Baculoviral IAP repeat-con... 76 2e-13 gi|1170468|sp|P41435|IAP1_NPVAC Apoptosis inhibitor 1 (IAP-1) 74 7e-13 gi|3183409|sp|O14064|BIR1_SCHPO Bir1 protein (Chromosome se... 67 9e-11 gi|12585184|sp|Q9JHY7|BIR5_RAT Baculoviral IAP repeat-conta... 59 3e-08 gi|6647548|sp|O70201|BIR5_MOUSE Baculoviral IAP repeat-cont... 57 1e-07 gi|6647543|sp|O15392|BIR5_HUMAN Baculoviral IAP repeat-cont... 51 9e-06 gi|1170469|sp|P41454|IAP2_NPVAC Probable apoptosis inhibito... 47 2e-04 gi|34395860|sp|Q86B79|UNK_DROME Unkempt protein 44 8e-04 gi|732428|sp|P40629|ZEF2_IRV6 Zinc finger protein 42 0.003 gi|2501727|sp|O10324|IAP2_NPVOP Probable apoptosis inhibito... 41 0.009 gi|20139692|sp|Q9BY78|RN26_HUMAN RING finger protein 26 40 0.018 gi|32129904|sp|Q93WF1|PL20_ARATH Probable pectate lyase 20 ... 39 0.028 gi|44887777|sp|Q8BMJ7|CGF1_MOUSE Cell growth regulator with... 38 0.054 gi|44887778|sp|Q99675|CGF1_HUMAN Cell growth regulator with... 38 0.061 gi|44887774|sp|P97587|CGF1_RAT Cell growth regulator with R... 37 0.17 gi|34223722|sp|P29503|NEUR_DROME Neuralized protein 36 0.22 gi|2497248|sp|O11451|IAPL_ASFC3 IAP-like protein p27 35 0.37 gi|34222692|sp|Q24746|NEUR_DROVI Neuralized protein 35 0.46 gi|2497250|sp|O11453|IAPL_ASFM2 IAP-like protein p27 35 0.47 gi|8928035|sp|Q9ULV8|CBLC_HUMAN Signal transduction protein... 35 0.51 gi|8928017|sp|Q13191|CBLB_HUMAN Signal transduction protein... 35 0.72 gi|32130094|sp|Q87AB6|SYFB_XYLFT Phenylalanyl-tRNA syntheta... 35 0.72 gi|12229991|sp|Q9PFD6|SYFB_XYLFA Phenylalanyl-tRNA syntheta... 34 1.0 gi|8472490|sp|O15151|MDM4_HUMAN Mdm4 protein (p53-binding p... 34 1.1 gi|2497249|sp|O11452|IAPL_ASFM1 IAP-like protein p27 34 1.2 gi|2497247|sp|O12407|IAPL_ASFCH IAP-like protein p27 33 1.4 gi|8472518|sp|P56950|MDM2_CANFA Ubiquitin-protein ligase E3... 33 1.7 gi|115855|sp|P22681|CBL_HUMAN CBL E3 ubiquitin protein liga... 33 1.9 gi|38605691|sp|P22682|CBL_MOUSE CBL E3 ubiquitin protein li... 33 1.9 gi|2497246|sp|Q65138|IAPL_ASFB7 IAP-like protein p27 33 2.4 gi|1175073|sp|P41449|Y044_NPVAC Hypothetical 15.0 kDa prote... 32 3.1 gi|6686191|sp|O50093|YD85_PYRHO Hypothetical protein PH1385 32 3.3 gi|133250|sp|P19474|RO52_HUMAN 52 kDa Ro protein (Sjogren s... 32 4.4 gi|8472521|sp|P56951|MDM2_HORSE Ubiquitin-protein ligase E3... 32 4.4 gi|141470|sp|P19658|EX70_YEAST 70 kDa exocyst complex protein 32 4.7 gi|41017235|sp|Q9PHU4|GCH2_CAMJE Riboflavin biosynthesis pr... 32 4.7 gi|137403|sp|P24768|VA55_VACCV Protein A55 31 7.2 gi|137402|sp|P21073|VA55_VACCC Protein A55 31 7.3 gi|8472493|sp|O35618|MDM4_MOUSE Mdm4 protein (p53-binding p... 31 8.1 Alignments
Score E Sequences producing significant alignments: (bits) Value gi|12643387|sp|P98170|BIR4_HUMAN Baculoviral IAP repeat-con... 1038 0.0 gi|12585185|sp|Q9R0I6|BIR4_RAT Baculoviral IAP repeat-conta... 938 0.0 gi|2497241|sp|Q60989|BIR4_MOUSE Baculoviral IAP repeat-cont... 924 0.0 gi|21759007|sp|Q95M72|BIR8_PANTR Baculoviral IAP repeat-con... 402 e-112 gi|21759006|sp|Q95M71|BIR8_GORGO Baculoviral IAP repeat-con... 401 e-111 gi|21759009|sp|Q96P09|BIR8_HUMAN Baculoviral IAP repeat-con... 401 e-111 gi|2497238|sp|Q13490|BIR2_HUMAN Baculoviral IAP repeat-cont... 283 6e-76 gi|2497239|sp|Q62210|BIR2_MOUSE Baculoviral IAP repeat-cont... 278 2e-74 gi|2497236|sp|Q13489|BIR3_HUMAN Baculoviral IAP repeat-cont... 271 2e-72 gi|2497237|sp|O08863|BIR3_MOUSE Baculoviral IAP repeat-cont... 264 4e-70 gi|2497240|sp|Q90660|BIR_CHICK Inhibitor of apoptosis prote... 263 9e-70 gi|2497244|sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhi... 234 4e-61 gi|3914339|sp|O62640|PIAP_PIG Putative inhibitor of apoptosis 232 2e-60 gi|12643317|sp|Q9R016|BIRE_MOUSE Baculoviral IAP repeat-con... 163 1e-39 gi|12585188|sp|Q9JIB3|BIRG_MOUSE Baculoviral IAP repeat-con... 163 1e-39 gi|12643314|sp|Q9JIB6|BIRF_MOUSE Baculoviral IAP repeat-con... 162 3e-39 gi|12643316|sp|Q9QWK5|BIRA_MOUSE Baculoviral IAP repeat-con... 154 6e-37 gi|12643315|sp|Q9QUK4|BIRB_MOUSE Baculoviral IAP repeat-con... 150 7e-36 gi|1170471|sp|P41437|IAP3_NPVOP Apoptosis inhibitor 3 (IAP-3) 145 2e-34 gi|12643291|sp|Q13075|BIR1_HUMAN Baculoviral IAP repeat-con... 144 6e-34 gi|1170470|sp|P41436|IAP_GVCP Apoptosis inhibitor IAP 131 4e-30 gi|2497243|sp|Q24306|IAP1_DROME Apoptosis 1 inhibitor (Inhi... 128 5e-29 gi|21759008|sp|Q96CA5|BIR7_HUMAN Baculoviral IAP repeat-con... 99 4e-20 gi|33302608|sp|P47732|ZFP_IRV6 Zinc finger protein 78 5e-14 gi|2497245|sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 (IAP-1) 77 9e-14 gi|12585192|sp|Q9NR09|BIR6_HUMAN Baculoviral IAP repeat-con... 76 2e-13 gi|1170468|sp|P41435|IAP1_NPVAC Apoptosis inhibitor 1 (IAP-1) 74 7e-13 gi|3183409|sp|O14064|BIR1_SCHPO Bir1 protein (Chromosome se... 67 9e-11 gi|12585184|sp|Q9JHY7|BIR5_RAT Baculoviral IAP repeat-conta... 59 3e-08 gi|6647548|sp|O70201|BIR5_MOUSE Baculoviral IAP repeat-cont... 57 1e-07 gi|6647543|sp|O15392|BIR5_HUMAN Baculoviral IAP repeat-cont... 51 9e-06 gi|1170469|sp|P41454|IAP2_NPVAC Probable apoptosis inhibito... 47 2e-04 gi|34395860|sp|Q86B79|UNK_DROME Unkempt protein 44 8e-04 gi|732428|sp|P40629|ZEF2_IRV6 Zinc finger protein 42 0.003 gi|2501727|sp|O10324|IAP2_NPVOP Probable apoptosis inhibito... 41 0.009 gi|20139692|sp|Q9BY78|RN26_HUMAN RING finger protein 26 40 0.018 gi|32129904|sp|Q93WF1|PL20_ARATH Probable pectate lyase 20 ... 39 0.028 gi|44887777|sp|Q8BMJ7|CGF1_MOUSE Cell growth regulator with... 38 0.054 gi|44887778|sp|Q99675|CGF1_HUMAN Cell growth regulator with... 38 0.061 gi|44887774|sp|P97587|CGF1_RAT Cell growth regulator with R... 37 0.17 gi|34223722|sp|P29503|NEUR_DROME Neuralized protein 36 0.22 gi|2497248|sp|O11451|IAPL_ASFC3 IAP-like protein p27 35 0.37 gi|34222692|sp|Q24746|NEUR_DROVI Neuralized protein 35 0.46 gi|2497250|sp|O11453|IAPL_ASFM2 IAP-like protein p27 35 0.47 gi|8928035|sp|Q9ULV8|CBLC_HUMAN Signal transduction protein... 35 0.51 gi|8928017|sp|Q13191|CBLB_HUMAN Signal transduction protein... 35 0.72 gi|32130094|sp|Q87AB6|SYFB_XYLFT Phenylalanyl-tRNA syntheta... 35 0.72 gi|12229991|sp|Q9PFD6|SYFB_XYLFA Phenylalanyl-tRNA syntheta... 34 1.0 gi|8472490|sp|O15151|MDM4_HUMAN Mdm4 protein (p53-binding p... 34 1.1 gi|2497249|sp|O11452|IAPL_ASFM1 IAP-like protein p27 34 1.2 gi|2497247|sp|O12407|IAPL_ASFCH IAP-like protein p27 33 1.4 gi|8472518|sp|P56950|MDM2_CANFA Ubiquitin-protein ligase E3... 33 1.7 gi|115855|sp|P22681|CBL_HUMAN CBL E3 ubiquitin protein liga... 33 1.9 gi|38605691|sp|P22682|CBL_MOUSE CBL E3 ubiquitin protein li... 33 1.9 gi|2497246|sp|Q65138|IAPL_ASFB7 IAP-like protein p27 33 2.4 gi|1175073|sp|P41449|Y044_NPVAC Hypothetical 15.0 kDa prote... 32 3.1 gi|6686191|sp|O50093|YD85_PYRHO Hypothetical protein PH1385 32 3.3 gi|133250|sp|P19474|RO52_HUMAN 52 kDa Ro protein (Sjogren s... 32 4.4 gi|8472521|sp|P56951|MDM2_HORSE Ubiquitin-protein ligase E3... 32 4.4 gi|141470|sp|P19658|EX70_YEAST 70 kDa exocyst complex protein 32 4.7 gi|41017235|sp|Q9PHU4|GCH2_CAMJE Riboflavin biosynthesis pr... 32 4.7 gi|137403|sp|P24768|VA55_VACCV Protein A55 31 7.2 gi|137402|sp|P21073|VA55_VACCC Protein A55 31 7.3 gi|8472493|sp|O35618|MDM4_MOUSE Mdm4 protein (p53-binding p... 31 8.1
>gi|12643387|sp|P98170|BIR4_HUMAN Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP-like protein) (HILP) Length = 497 Score = 1038 bits (2685), Expect = 0.0 Identities = 487/497 (97%), Positives = 487/497 (97%) Query: 105 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 164 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT Sbjct: 1 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 60 Query: 165 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 224 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY Sbjct: 61 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 120 Query: 225 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 284 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT Sbjct: 121 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 180 Query: 285 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 344 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE Sbjct: 181 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 240 Query: 345 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 404 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC Sbjct: 241 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 300 Query: 405 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 464 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP Sbjct: 301 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 360 Query: 465 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 524 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD Sbjct: 361 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 420 Query: 525 SMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 584 SMQDESSQTSLQKEIST KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK Sbjct: 421 SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 480 Query: 585 CPMCYTVITFKQKIFMS 601 CPMCYTVITFKQKIFMS Sbjct: 481 CPMCYTVITFKQKIFMS 497
>gi|12585185|sp|Q9R0I6|BIR4_RAT Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (RIAP3) (RIAP-3) Length = 496 Score = 938 bits (2425), Expect = 0.0 Identities = 436/497 (87%), Positives = 465/497 (93%), Gaps = 1/497 (0%) Query: 105 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 164 MTFNSFEGS+T VPAD NK+EEFVEEFNRLKTFANFPS SPVSASTLARAGFLYTGEGDT Sbjct: 1 MTFNSFEGSRTVVPADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDT 60 Query: 165 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 224 V+CFSCHAAVDRWQYGDSAVGRHR++SPNCRFINGFY EN ATQST+ GIQNGQYK EN Sbjct: 61 VQCFSCHAAVDRWQYGDSAVGRHRRISPNCRFINGFYFENGATQSTSPGIQNGQYKSENC 120 Query: 225 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 284 +G+R+HFALDRPSETHADYLLRTGQVVDISDTIYPRNPAM SEEARLK+FQNWPDYAHL+ Sbjct: 121 VGNRNHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKTFQNWPDYAHLS 180 Query: 285 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 344 PRELASAGLYYTGI DQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN+N+RSE Sbjct: 181 PRELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSE 240 Query: 345 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 404 S VSSDRNFPNSTN PRNP+MA+Y+ARI TFGTW+YSVNKEQLARAGFYALGEGDKVKC Sbjct: 241 S-GVSSDRNFPNSTNSPRNPAMAEYDARIVTFGTWLYSVNKEQLARAGFYALGEGDKVKC 299 Query: 405 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 464 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLL++KGQEYINNIHLTHSL E +VRT EKTP Sbjct: 300 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLGESVVRTAEKTP 359 Query: 465 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 524 S+T++IDDTIFQNPMVQEAIRMGF+FKDIKK MEEK+Q SGSNY SLEVL+ADLV+AQKD Sbjct: 360 SVTKKIDDTIFQNPMVQEAIRMGFNFKDIKKTMEEKLQTSGSNYLSLEVLIADLVSAQKD 419 Query: 525 SMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 584 + QDESSQTSLQK+IST KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK Sbjct: 420 NSQDESSQTSLQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 479 Query: 585 CPMCYTVITFKQKIFMS 601 CPMC TVITFKQKIFMS Sbjct: 480 CPMCCTVITFKQKIFMS 496
>gi|2497241|sp|Q60989|BIR4_MOUSE Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis protein 3) (X-linked inhibitor of apoptosis protein) (X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3) Length = 496 Score = 924 bits (2389), Expect = 0.0 Identities = 433/497 (87%), Positives = 458/497 (92%), Gaps = 1/497 (0%) Query: 105 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT 164 MTFNSFEG++T V AD NK+EEFVEEFNRLKTFANFPS SPVSASTLARAGFLYTGEGDT Sbjct: 1 MTFNSFEGTRTFVLADTNKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDT 60 Query: 165 VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY 224 V+CFSCHAA+DRWQYGDSAVGRHR++SPNCRFINGFY EN A QSTN GIQNGQYK EN Sbjct: 61 VQCFSCHAAIDRWQYGDSAVGRHRRISPNCRFINGFYFENGAAQSTNPGIQNGQYKSENC 120 Query: 225 LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT 284 +G+R+ FA DRP ETHADYLLRTGQVVDISDTIYPRNPAM SEEARLKSFQNWPDYAHLT Sbjct: 121 VGNRNPFAPDRPPETHADYLLRTGQVVDISDTIYPRNPAMCSEEARLKSFQNWPDYAHLT 180 Query: 285 PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE 344 PRELASAGLYYTG DQVQCFCCGGKL+NWEPCDRAWSEHRRHFPNCFFVLGRN+N+RSE Sbjct: 181 PRELASAGLYYTGADDQVQCFCCGGKLENWEPCDRAWSEHRRHFPNCFFVLGRNVNVRSE 240 Query: 345 SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC 404 S VSSDRNFPNSTN PRNP+MA+YEARI TFGTW SVNKEQLARAGFYALGEGDKVKC Sbjct: 241 S-GVSSDRNFPNSTNSPRNPAMAEYEARIVTFGTWTSSVNKEQLARAGFYALGEGDKVKC 299 Query: 405 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP 464 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLL++KGQEYINNIHLTHSLEE L RT EKTP Sbjct: 300 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLDEKGQEYINNIHLTHSLEESLGRTAEKTP 359 Query: 465 SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD 524 SLT++IDDTIFQNPMVQEAIRMGFSFKDIKK MEEKIQ SGS+Y SLEVL+ADLV+AQKD Sbjct: 360 SLTKKIDDTIFQNPMVQEAIRMGFSFKDIKKTMEEKIQTSGSSYLSLEVLIADLVSAQKD 419 Query: 525 SMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 584 + +DESSQTSLQK+IST KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK Sbjct: 420 NTEDESSQTSLQKDISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK 479 Query: 585 CPMCYTVITFKQKIFMS 601 CPMCYTVITFKQKIFMS Sbjct: 480 CPMCYTVITFKQKIFMS 496
>gi|21759007|sp|Q95M72|BIR8_PANTR Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) Length = 236 Score = 402 bits (1034), Expect = e-112 Identities = 180/236 (76%), Positives = 207/236 (87%) Query: 366 MADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHA 425 M YEAR+ TFGTW+Y VNKEQLARAGFYA+G+ DKV+CFHCGGGL +WKP EDPWEQHA Sbjct: 1 MTGYEARLITFGTWMYFVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHA 60 Query: 426 KWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIR 485 KWYPGCKYLLE+KG EYINNIHLT SLE LV+TT+KTPSLT+RI+DTIF NPM+QEAIR Sbjct: 61 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRINDTIFPNPMLQEAIR 120 Query: 486 MGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTXXXX 545 MGF FKD+KKIMEE+IQ SGSNYK+LEVLVADLV+AQKD+ ++ES+QTSLQ+EIS Sbjct: 121 MGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENESNQTSLQREISPEEPL 180 Query: 546 XXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 KLCKICMDR+IA+VF+PCGHLVTCKQCAEAVD+CPMC VI FKQ++FMS Sbjct: 181 RRLQDEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS 236
Score = 66.6 bits (161), Expect = 1e-10 Identities = 30/72 (41%), Positives = 42/72 (58%), Gaps = 2/72 (2%) Query: 264 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 323 M EARL +F W + + +LA AG Y G D+VQCF CGG L NW+P + W + Sbjct: 1 MTGYEARLITFGTWMYF--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58 Query: 324 HRRHFPNCFFVL 335 H + +P C ++L Sbjct: 59 HAKWYPGCKYLL 70
Score = 43.1 bits (100), Expect = 0.002 Identities = 18/52 (34%), Positives = 28/52 (53%) Query: 146 VSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 197 V+ LARAGF G+ D V+CF C + W+ + +H K P C+++ Sbjct: 18 VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYL 69
>gi|21759006|sp|Q95M71|BIR8_GORGO Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) Length = 236 Score = 401 bits (1031), Expect = e-111 Identities = 181/236 (76%), Positives = 206/236 (87%) Query: 366 MADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHA 425 M YEA + TFGTW+YSVNKEQLARAGFYA+G+ DK++CFHCGGGL +WKP EDPWEQHA Sbjct: 1 MTGYEAWLITFGTWMYSVNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQHA 60 Query: 426 KWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIR 485 KWYPGCKYLLE+KG EYINNIHLT SLE LV+TT+KTPSLT+RI DTIF NPM+QEAIR Sbjct: 61 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIR 120 Query: 486 MGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTXXXX 545 MGF FKDIKKIMEEKIQ SGSNYK+LEVLVADLV+AQKD+ ++ES+QTSLQ+EIS Sbjct: 121 MGFDFKDIKKIMEEKIQTSGSNYKTLEVLVADLVSAQKDTTENESNQTSLQREISPEEPL 180 Query: 546 XXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 KLCKICMDR+IA+VF+PCGHLVTCKQCAEAVD+CPMC VI FKQ++FMS Sbjct: 181 RRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCNAVIDFKQRVFMS 236
Score = 62.4 bits (150), Expect = 3e-09 Identities = 28/72 (38%), Positives = 40/72 (55%), Gaps = 2/72 (2%) Query: 264 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 323 M EA L +F W + +LA AG Y G D++QCF CGG L NW+P + W + Sbjct: 1 MTGYEAWLITFGTW--MYSVNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQ 58 Query: 324 HRRHFPNCFFVL 335 H + +P C ++L Sbjct: 59 HAKWYPGCKYLL 70
Score = 42.7 bits (99), Expect = 0.003 Identities = 17/52 (32%), Positives = 28/52 (53%) Query: 146 VSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 197 V+ LARAGF G+ D ++CF C + W+ + +H K P C+++ Sbjct: 18 VNKEQLARAGFYAIGQEDKIQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYL 69
>gi|21759009|sp|Q96P09|BIR8_HUMAN Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis) Length = 236 Score = 401 bits (1030), Expect = e-111 Identities = 180/236 (76%), Positives = 205/236 (86%) Query: 366 MADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHA 425 M YEAR+ TFGTW+YSVNKEQLARAGFYA+G+ DKV+CFHCGGGL +WKP EDPWEQHA Sbjct: 1 MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHA 60 Query: 426 KWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIR 485 KWYPGCKYLLE+KG EYINNIHLT SLE LV+TT+KTPSLT+RI DTIF NPM+QEAIR Sbjct: 61 KWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIR 120 Query: 486 MGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTXXXX 545 MGF FKD+KKIMEE+IQ SGSNYK+LEVLVADLV+AQKD+ ++E +QTSLQ+EIS Sbjct: 121 MGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPL 180 Query: 546 XXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 KLCKICMDR IA+VF+PCGHLVTCKQCAEAVD+CPMC VI FKQ++FMS Sbjct: 181 RRLQEEKLCKICMDRYIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS 236
Score = 66.2 bits (160), Expect = 2e-10 Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 2/72 (2%) Query: 264 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 323 M EARL +F W + +LA AG Y G D+VQCF CGG L NW+P + W + Sbjct: 1 MTGYEARLITFGTW--MYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58 Query: 324 HRRHFPNCFFVL 335 H + +P C ++L Sbjct: 59 HAKWYPGCKYLL 70
Score = 43.9 bits (102), Expect = 0.001 Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 133 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 192 RL TF + V+ LARAGF G+ D V+CF C + W+ + +H K P Sbjct: 7 RLITFGTWMYS--VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYP 64 Query: 193 NCRFI 197 C+++ Sbjct: 65 GCKYL 69
>gi|2497238|sp|Q13490|BIR2_HUMAN Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B) Length = 618 Score = 283 bits (725), Expect = 6e-76 Identities = 161/420 (38%), Positives = 228/420 (54%), Gaps = 48/420 (11%) Query: 126 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 +F E R+ T++ FP+G PVS +LARAGF YTG D V+CF C +D W+ GDS + Sbjct: 42 DFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQ 101 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQY------KVENYLGSRDHFALDRPSET 239 +H+++ P+C FI + + S N+ + +E+ ++ P+ Sbjct: 102 KHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNP- 160 Query: 240 HADYLLRTGQVVDISDT-IYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGI 298 L + V DIS + P + AM +EEAR ++ WP L+P ELA AG YY G Sbjct: 161 -----LNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWP-LTFLSPSELARAGFYYIGP 214 Query: 299 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNST 358 GD+V CF CGGKL NWEP D A SEHRRHFPNC F+ +R F S Sbjct: 215 GDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLETLR-----------FSIS- 262 Query: 359 NLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLTDWKP 416 N SM + AR+ TF W SV EQLA AGFY +G D VKCF C GGL W+ Sbjct: 263 ----NLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWES 318 Query: 417 SEDPWEQHAKWYPGCKYLLEQKGQEYINNIH--LTHSLEECLVRTTEKT----------- 463 +DPW +HAKW+P C++L+ KGQE+++ I H LE+ L+ T++ T Sbjct: 319 GDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQ-LLSTSDTTGEENADPPIIH 377 Query: 464 --PSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNA 521 P + D + P+V+ A+ MGF+ +K+ ++ KI +G NYK++ +V+ L+NA Sbjct: 378 FGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNA 437
Score = 68.9 bits (167), Expect = 3e-11 Identities = 23/50 (46%), Positives = 38/50 (76%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 + CK+CMD+ +++VF+PCGHLV C++CA ++ KCP+C +I + F+S Sbjct: 569 RTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
Score = 62.4 bits (150), Expect = 3e-09 Identities = 37/99 (37%), Positives = 53/99 (53%), Gaps = 6/99 (6%) Query: 340 NIRS--ESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI--YSVNKEQLARAGFYA 395 NI+S E + SD N + + S Y R+ T+ T+ V++ LARAGFY Sbjct: 17 NIKSIMEDSTILSDWTNSNKQKMKYDFSCELY--RMSTYSTFPAGVPVSERSLARAGFYY 74 Query: 396 LGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYL 434 G DKVKCF CG L +WK + P ++H + YP C ++ Sbjct: 75 TGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFI 113
>gi|2497239|sp|Q62210|BIR2_MOUSE Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (MIAP2) (MIAP-2) Length = 612 Score = 278 bits (712), Expect = 2e-74 Identities = 168/439 (38%), Positives = 237/439 (53%), Gaps = 62/439 (14%) Query: 114 KTCVPADINKEEE------FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRC 167 K+ + ++ KE E F E R+ T++ FP G PVS +LARAGF YTG D V+C Sbjct: 24 KSTILSNWTKESEEKMKFDFSCELYRMSTYSAFPRGVPVSERSLARAGFYYTGVNDKVKC 83 Query: 168 FSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGS 227 F C +D W+ GDS V +HR+ P+C F+ L +++ QS + +N Sbjct: 84 FCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQT--LLSASLQSPS----------KNMSPV 131 Query: 228 RDHFALDRPSE---THADYL---LRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYA 281 + FA P E H++ L + V D S + P + AM +EEAR ++ WP + Sbjct: 132 KSRFAHSSPLERGGIHSNLCSSPLNSRAVEDFSSRMDPCSYAMSTEEARFLTYSMWP-LS 190 Query: 282 HLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNI 341 L+P ELA AG YY G GD+V CF CGGKL NWEP D A SEHRRHFP+C F+ Sbjct: 191 FLSPAELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPHCPFL------- 243 Query: 342 RSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEG 399 + S + F S N SM + AR+ TF W SV EQLA AGFY + Sbjct: 244 ----ENTSETQRFSIS-----NLSMQTHSARLRTFLYWPPSVPVQPEQLASAGFYYVDRN 294 Query: 400 DKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIH--LTHSLEECLV 457 D VKCF C GGL W+P +DPW +HAKW+P C++L+ KGQE+++ I H LE+ L Sbjct: 295 DDVKCFCCDGGLRCWEPGDDPWIEHAKWFPRCEFLIRMKGQEFVDEIQARYPHLLEQLL- 353 Query: 458 RTTEKTP-----SLTRRI----------DDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQ 502 +T TP T + D + P+V+ A+ MGFS +++ ++ +I Sbjct: 354 -STSDTPGEENADPTETVVHFGPGESSEDVVMMSTPVVKAALEMGFSRSLVRQTVQRQIL 412 Query: 503 ISGSNYKSLEVLVADLVNA 521 +G NY+++ +V+ L+NA Sbjct: 413 ATGENYRTVNDIVSVLLNA 431
Score = 69.7 bits (169), Expect = 2e-11 Identities = 25/50 (50%), Positives = 37/50 (74%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 + CK+CMDR ++IVF+PCGHLV C++CA ++ KCP+C I + F+S Sbjct: 563 RTCKVCMDREVSIVFIPCGHLVVCQECAPSLRKCPICRGTIKGTVRTFLS 612
>gi|2497236|sp|Q13489|BIR3_HUMAN Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C) (Apoptosis inhibitor 2) (API2) Length = 604 Score = 271 bits (694), Expect = 2e-72 Identities = 159/411 (38%), Positives = 215/411 (52%), Gaps = 59/411 (14%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 189 E R+ T++ FP+G PVS +LARAGF YTG D V+CF C +D W+ GDS +H+K Sbjct: 29 ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKK 88 Query: 190 VSPNCRFINGFYLEN------------SATQSTNS---GIQNGQYKVENYLGSRDHFALD 234 + P+CRF+ N S T ST+S G +N Y +Y S + Sbjct: 89 LYPSCRFVQSLNSVNNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNS 148 Query: 235 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 294 R ++ + L+R+ + AM +E ARL +FQ WP L+P +LA AG Y Sbjct: 149 RANQDFSA-LMRSSY-----------HCAMNNENARLLTFQTWP-LTFLSPTDLAKAGFY 195 Query: 295 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 354 Y G GD+V CF CGGKL NWEP D A SEH RHFP C F+ E+ + R Sbjct: 196 YIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFI---------ENQLQDTSRYT 246 Query: 355 PNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLT 412 + N SM + AR TF W SV N EQLA AGFY +G D VKCF C GGL Sbjct: 247 VS------NLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR 300 Query: 413 DWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHS-LEECLVRTTEK--------- 462 W+ +DPW QHAKW+P C+YL+ KGQE+I + ++ L E L+ T++ Sbjct: 301 CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS 360 Query: 463 ----TPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYK 509 P D + P++ A+ MGFS +K+ ++ KI +G NY+ Sbjct: 361 IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYR 411
Score = 69.7 bits (169), Expect = 2e-11 Identities = 25/50 (50%), Positives = 37/50 (74%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 + CK+CMD+ ++IVF+PCGHLV CK CA ++ KCP+C + I + F+S Sbjct: 555 RTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS 604
Score = 64.7 bits (156), Expect = 6e-10 Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 7/113 (6%) Query: 339 LNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI--YSVNKEQLARAGFYAL 396 +NI S +S+ N+ L + S Y R+ T+ T+ V++ LARAGFY Sbjct: 1 MNIVENSIFLSNLMKSANTFELKYDLSCELY--RMSTYSTFPAGVPVSERSLARAGFYYT 58 Query: 397 GEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLT 449 G DKVKCF CG L +WK + P E+H K YP C+++ + +NN+ T Sbjct: 59 GVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFV---QSLNSVNNLEAT 108
>gi|2497237|sp|O08863|BIR3_MOUSE Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis protein 1) (MIAP1) (MIAP-1) Length = 600 Score = 264 bits (675), Expect = 4e-70 Identities = 158/427 (37%), Positives = 224/427 (52%), Gaps = 54/427 (12%) Query: 126 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 +F E RL T++ FP G PVS +LARAGF YTG D V+CF C +D W+ GDS + Sbjct: 23 DFSCELYRLSTYSAFPRGVPVSERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPME 82 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKV--------EN---YLGSRDHFALD 234 +HRK+ P+C F+ NS S + + EN + GS F D Sbjct: 83 KHRKLYPSCNFVQTLNPANSLEASPRPSLPSTAMSTMPLSFASSENTGYFSGSYSSFPSD 142 Query: 235 RPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLY 294 + R Q T P + AM +E+ARL +++ WP + L+P +LA AG Y Sbjct: 143 PVN-------FRANQDCPALST-SPYHFAMNTEKARLLTYETWP-LSFLSPAKLAKAGFY 193 Query: 295 YTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNF 354 Y G GD+V CF C GKL NWE D A SEH+RHFP+C F+ ++L + VS Sbjct: 194 YIGPGDRVACFACDGKLSNWERKDDAMSEHQRHFPSCPFL--KDLGQSASRYTVS----- 246 Query: 355 PNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLT 412 N SM + ARI TF W S V+ ++LA AGFY G D VKCF C GGL Sbjct: 247 --------NLSMQTHAARIRTFSNWPSSALVHSQELASAGFYYTGHSDDVKCFCCDGGLR 298 Query: 413 DWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIH--LTHSLEECLVRTTEKTPSLTR-- 468 W+ +DPW +HAKW+P C+YLL KGQE+++ + H LE+ L +T +P Sbjct: 299 CWESGDDPWVEHAKWFPRCEYLLRIKGQEFVSQVQAGYPHLLEQLL--STSDSPEDENAD 356 Query: 469 -----------RIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVAD 517 D + P+V+ A+ MGFS +++ ++ +I +G NY+++ LV Sbjct: 357 AAIVHFGPGESSEDVVMMSTPVVKAALEMGFSRSLVRQTVQRQILATGENYRTVSDLVIG 416 Query: 518 LVNAQKD 524 L++A+ + Sbjct: 417 LLDAEDE 423
Score = 71.2 bits (173), Expect = 6e-12 Identities = 26/50 (52%), Positives = 37/50 (74%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 ++CK+CMDR ++IVF+PCGHLV CK CA ++ KCP+C I + F+S Sbjct: 551 RMCKVCMDREVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTVRTFLS 600
>gi|2497240|sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis protein) Length = 611 Score = 263 bits (672), Expect = 9e-70 Identities = 164/431 (38%), Positives = 221/431 (51%), Gaps = 61/431 (14%) Query: 126 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 +F E R+ TF+ FP PVS LARAGF YTG D V+CFSC +D WQ GD+A+ Sbjct: 26 DFSCELYRMSTFSTFPVNVPVSERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAME 85 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSG-----------------IQNGQYKVENYLGSR 228 +H++V P+C F+ N+ ST+S + +V + GS Sbjct: 86 KHKQVYPSCSFVQNMLSLNNLGLSTHSAFSPLVASNLSPSLRSMTLSPSFEQVGYFSGSF 145 Query: 229 DHFALDRPSETHADYL--LRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPR 286 F D + A+ L LR+ +NP+M +EEARL++ WP L P Sbjct: 146 SSFPRDPVTTRAAEDLSHLRSKL----------QNPSMSTEEARLRTSHAWP-LMCLWPA 194 Query: 287 ELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESD 346 E+A AGL G D+V C CG KL NWEP D A SEHRRHFPNC FV NL S Sbjct: 195 EVAKAGLDDLGTADKVACVNCGVKLSNWEPKDNAMSEHRRHFPNCPFV--ENLMRDQPSF 252 Query: 347 AVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI--YSVNKEQLARAGFYALGEGDKVKC 404 VS N +M +EAR+ TF W V EQLA AGFY +G D VKC Sbjct: 253 NVS-------------NVTMQTHEARVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKC 299 Query: 405 FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIH--LTHSLEECLVRTTEK 462 F C GGL W+ +DPW +HAKW+P C+YLL KG E+++ + H L T++K Sbjct: 300 FCCDGGLRCWESGDDPWIEHAKWFPRCEYLLRVKGGEFVSQVQARFPHLLWNSSCTTSDK 359 Query: 463 ------------TPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKS 510 P + D + P+V+ A+ MGFS + IK+ ++ KI + NYK+ Sbjct: 360 PVDENMDPIIHFEPGESPSEDAIMMNTPVVKAALEMGFSRRLIKQTVQSKILATEENYKT 419 Query: 511 LEVLVADLVNA 521 + LV++L+ A Sbjct: 420 VNDLVSELLTA 430
Score = 74.3 bits (181), Expect = 8e-13 Identities = 44/150 (29%), Positives = 75/150 (50%), Gaps = 22/150 (14%) Query: 452 LEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSL 511 LE +++ T +TPS R + DT+ +I KD ++ + + + KS+ Sbjct: 484 LEHDVIKQTTQTPSQARELIDTVLVKGNAAASIFRN-CLKDFDPVLYKDLFVE----KSM 538 Query: 512 EVLVADLVNAQKDSMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGH 571 + + + V+ + E LQ+E + CK+CMD+ ++IVF+PCGH Sbjct: 539 KYVPTEDVSG----LPMEEQLRRLQEE-------------RTCKVCMDKEVSIVFIPCGH 581 Query: 572 LVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 LV CK+CA ++ KCP+C I + F+S Sbjct: 582 LVVCKECAPSLRKCPICRGTIKGTVRTFLS 611
>gi|2497244|sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP) (IAP homolog A) (IAP-like protein) (DILP) Length = 498 Score = 234 bits (598), Expect = 4e-61 Identities = 154/532 (28%), Positives = 229/532 (43%), Gaps = 108/532 (20%) Query: 133 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 192 RL TF +P +PVSA L GF TG C CH +DRW+YGD RHR+ SP Sbjct: 12 RLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSP 71 Query: 193 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 252 C + N+ G+ + R E+ + VVD Sbjct: 72 ICSMV----------------------LAPNHCGN-----VPRSQESDNE----GNSVVD 100 Query: 253 ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLK 312 ++ P + E RL +F++WP+ ++TP+ LA AG YY D V+C C G + Sbjct: 101 SPESC--SCPDLLLEANRLVTFKDWPN-PNITPQALAKAGFYYLNRLDHVKCVWCNGVIA 157 Query: 313 NWEPCDRAWSEHRRHFPNC---------FFVLGRNLNIRSESDAVSSDRNFPNSTNLPRN 363 WE D A+ EH+R FP C F G+NL D T LP Sbjct: 158 KWEKNDNAFEEHKRFFPQCPRVQMGPLIEFATGKNL-----------DELGIQPTTLPLR 206 Query: 364 PSMADYEARIFTFGTWIYSVNK--EQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPW 421 P A +AR+ TF W S + LA+AG Y GD+V+CFHC GL W+ ++PW Sbjct: 207 PKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFHCNIGLRSWQKEDEPW 266 Query: 422 EQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRR------------ 469 +HAKW P C+++L KG Y++ + T + T P+L Sbjct: 267 FEHAKWSPKCQFVLLAKGPAYVSEVLATTAANASSPPATAPAPTLQADVLMDEAPAKEAL 326 Query: 470 ---IDDTIFQNPMVQEAIRMGFSFKDIKKIME-------------------------EKI 501 ID + +N + ++ + G +F + +++ E Sbjct: 327 ALGIDGGVVRNAIQRKLLSSGCAFSTLDELLHDIFDDAGAGAALEVREPPEPSAPFIEPC 386 Query: 502 QISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEI------------STXXXXXXXX 549 Q + S S+ + VAD + A+ + + ++ + + EI S Sbjct: 387 QATTSKAASVPIPVADSIPAKPQAAEAVANISKITDEIQKMSVATPNGNLSLEEENRQLK 446 Query: 550 XXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 +LCK+C+D + +VF+PCGHL TC QCA +V CPMC I + F+S Sbjct: 447 DARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIKGFVRTFLS 498
Score = 105 bits (261), Expect = 4e-22 Identities = 65/209 (31%), Positives = 93/209 (44%), Gaps = 44/209 (21%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 189 E NRL TF ++P+ + ++ LA+AGF Y D V+C C+ + +W+ D+A H++ Sbjct: 113 EANRLVTFKDWPNPN-ITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKR 171 Query: 190 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 249 P C + +G FA TG+ Sbjct: 172 FFPQCPRVQ--------------------------MGPLIEFA--------------TGK 191 Query: 250 VVD---ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFC 306 +D I T P P +ARL++F +WP LA AGLYY IGDQV+CF Sbjct: 192 NLDELGIQPTTLPLRPKYACVDARLRTFTDWPISNIQPASALAQAGLYYQKIGDQVRCFH 251 Query: 307 CGGKLKNWEPCDRAWSEHRRHFPNCFFVL 335 C L++W+ D W EH + P C FVL Sbjct: 252 CNIGLRSWQKEDEPWFEHAKWSPKCQFVL 280
Score = 91.7 bits (226), Expect = 5e-18 Identities = 50/172 (29%), Positives = 83/172 (48%), Gaps = 3/172 (1%) Query: 263 AMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWS 322 M E RL +F WP A ++ +L + G + TG + +C C ++ WE D+ Sbjct: 5 GMELESVRLATFGEWPLNAPVSAEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAE 64 Query: 323 EHRRHFPNCFFVLGRNL--NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWI 380 HRR P C VL N N+ ++ + + +S P + R+ TF W Sbjct: 65 RHRRSSPICSMVLAPNHCGNVPRSQESDNEGNSVVDSPESCSCPDLLLEANRLVTFKDWP 124 Query: 381 Y-SVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGC 431 ++ + LA+AGFY L D VKC C G + W+ +++ +E+H +++P C Sbjct: 125 NPNITPQALAKAGFYYLNRLDHVKCVWCNGVIAKWEKNDNAFEEHKRFFPQC 176
>gi|3914339|sp|O62640|PIAP_PIG Putative inhibitor of apoptosis Length = 358 Score = 232 bits (592), Expect = 2e-60 Identities = 138/376 (36%), Positives = 193/376 (51%), Gaps = 56/376 (14%) Query: 264 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 323 M +E+ RL +FQ WP L+P +LA AG YY G GD+V CF CGGKL NWEP D A +E Sbjct: 1 MNTEKDRLLTFQMWP-LTFLSPADLAKAGFYYIGPGDRVACFACGGKLSNWEPKDDAMTE 59 Query: 324 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS- 382 H RHFPNC F LG L S N SM Y AR TF W S Sbjct: 60 HLRHFPNCPF-LGNQLQDSSRYTV--------------SNLSMQTYAARFKTFCNWPSSI 104 Query: 383 -VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQE 441 V+ EQLA AGFY +G D VKCF C GGL W+ +DPW +HAKW+P C+YL+ KGQE Sbjct: 105 PVHPEQLASAGFYYMGHSDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEYLIRIKGQE 164 Query: 442 YINNIHLT--HSLEECLVRTTEKTP-----------SLTRRIDDTIFQN-----PMVQEA 483 +I+ + + H LE+ L +T P SL R+ +FQ+ P++ Sbjct: 165 FISRVQASYPHLLEQLL--STSDNPEDENAEPPNDLSLIRKNRMALFQHLTCVLPILDSL 222 Query: 484 IRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQ---KDSMQD------------ 528 + + ++++K Q S + +++++ A K+S+Q+ Sbjct: 223 LIARVISEQEHDVIKQKTQTSLQARELIDIILVKGNYAATIFKNSLQEIDPMLYKHLFVQ 282 Query: 529 ---ESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKC 585 + T ++S + CK+CMD+ ++IVF+PCGHLV CK CA ++ KC Sbjct: 283 QDIKYIPTENVSDLSMEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKC 342 Query: 586 PMCYTVITFKQKIFMS 601 P+C I + F+S Sbjct: 343 PICRGTIKGTVRTFLS 358
Score = 115 bits (288), Expect = 3e-25 Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 51/206 (24%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 189 E +RL TF +P + +S + LA+AGF Y G GD V CF+C + W+ D A+ H + Sbjct: 4 EKDRLLTFQMWPL-TFLSPADLAKAGFYYIGPGDRVACFACGGKLSNWEPKDDAMTEHLR 62 Query: 190 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 249 PNC F+ G L++S+ +Y V N Sbjct: 63 HFPNCPFL-GNQLQDSS-----------RYTVSNL------------------------- 85 Query: 250 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGG 309 +M + AR K+F NWP + P +LASAG YY G D V+CFCC G Sbjct: 86 -------------SMQTYAARFKTFCNWPSSIPVHPEQLASAGFYYMGHSDDVKCFCCDG 132 Query: 310 KLKNWEPCDRAWSEHRRHFPNCFFVL 335 L+ WE D W EH + FP C +++ Sbjct: 133 GLRCWESGDDPWVEHAKWFPRCEYLI 158
>gi|12643317|sp|Q9R016|BIRE_MOUSE Baculoviral IAP repeat-containing protein 1e (Neuronal apoptosis inhibitory protein 5) Length = 1403 Score = 163 bits (413), Expect = 1e-39 Identities = 114/356 (32%), Positives = 160/356 (44%), Gaps = 66/356 (18%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 185 E RLKTF + + + +A AGF +TG V+CF C + +G+S + Sbjct: 60 EAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 245 RH+K+ P C F+ G + N G+Y + + P + +L Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149 Query: 246 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 304 R G+ + EEARL+SF++WP YAH T PR L++AG +TG D VQC Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197 Query: 305 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN------IRSESDAVSSD------- 351 F CGG L NWE D W EH + FP C F+ + + I+S V Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKS 257 Query: 352 ---RNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFH 406 R P + + A+ E R+ F W V E L RAGF+ G+ D V+CF Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFS 317 Query: 407 CGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTE 461 CGG L W +DP E H K++P C +L K E I + ++L E T E Sbjct: 318 CGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRE 373
Score = 130 bits (327), Expect = 9e-30 Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 30/248 (12%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 315 N M SE RLK+F+ + + TP+E+A+AG Y+TG+ VQCFCC G L+ Sbjct: 54 NSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112 Query: 316 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 374 P +R H++ P C F+ G+++ NI V S P + EAR+ Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164 Query: 375 TFGTW---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGC 431 +F W + + L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKC 224 Query: 432 KYLLEQKGQE----YINNIH-LTHSLEECLVRT--TEKTPSLTRRIDDTIFQNPMVQEAI 484 ++L +K E YI + H E V++ + P ++ +D++F N E + Sbjct: 225 EFLQSKKSSEEIAQYIQSYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFAN----EEL 280 Query: 485 RMGFSFKD 492 RM FKD Sbjct: 281 RMDM-FKD 287
Score = 113 bits (282), Expect = 2e-24 Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 35/251 (13%) Query: 129 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 187 EE RL++F ++P S L+ AGF++TG+ DTV+CFSC ++ W+ GD H Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217 Query: 188 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 243 K P C F+ QS S + QY +++Y G + +HF + Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQSYEGFVHVTGEHFV--------KSW 258 Query: 244 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 303 + R +V + Y + +EE R+ F++WP + + L AG +YTG D V+ Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVR 314 Query: 304 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 360 CF CGG L+ W D +H + FP C F+ ++S ++ + S P +T Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370 Query: 361 PRNPSMADYEA 371 R + D A Sbjct: 371 TRESNHGDAAA 381
Score = 75.9 bits (185), Expect = 3e-13 Identities = 54/167 (32%), Positives = 74/167 (44%), Gaps = 27/167 (16%) Query: 127 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 186 F E R+ F ++P SPV L RAGF YTG+ D VRCFSC +++W GD + Sbjct: 275 FANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334 Query: 187 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 241 H K P C F+ L++SA E + +AL +ET H Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHG 377 Query: 242 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPREL 288 D VVD+ R+ A + +EAR S Q +Y T R + Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQLRDNYTKATFRHM 419
>gi|12585188|sp|Q9JIB3|BIRG_MOUSE Baculoviral IAP repeat-containing protein 1g (Neuronal apoptosis inhibitory protein 7) Length = 1402 Score = 163 bits (413), Expect = 1e-39 Identities = 113/356 (31%), Positives = 161/356 (45%), Gaps = 66/356 (18%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 185 E RLKTF ++ + + +A AGF +TG V+CF C + +G+S + Sbjct: 60 EAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 245 RH+K+ P C F+ G + N G+Y + + P + +L Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149 Query: 246 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 304 R G+ + EEARL+SF++WP YAH T PR L++AG +TG D VQC Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197 Query: 305 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS 349 F CGG L NWE D W EH + FP C F+ + +++ E S Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVKS 257 Query: 350 -SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFH 406 R P + + A+ E R+ F W V E L RAGF+ G+ D V+CF Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFS 317 Query: 407 CGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTE 461 CGG L W +DP E H K++P C +L K E I + ++L E T E Sbjct: 318 CGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRE 373
Score = 130 bits (326), Expect = 1e-29 Identities = 83/248 (33%), Positives = 127/248 (51%), Gaps = 30/248 (12%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 315 N M SE RLK+F+++ + TP+E+A+AG Y+TG+ VQCFCC G L+ Sbjct: 54 NSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112 Query: 316 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 374 P +R H++ P C F+ G+++ NI V S P + EAR+ Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164 Query: 375 TFGTW---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGC 431 +F W + + L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKC 224 Query: 432 KYLLEQKGQE----YINNIH-LTHSLEECLVRT--TEKTPSLTRRIDDTIFQNPMVQEAI 484 ++L +K E YI H E V++ + P ++ +D++F N E + Sbjct: 225 EFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFAN----EEL 280 Query: 485 RMGFSFKD 492 RM FKD Sbjct: 281 RMDM-FKD 287
Score = 112 bits (280), Expect = 3e-24 Identities = 74/251 (29%), Positives = 116/251 (46%), Gaps = 35/251 (13%) Query: 129 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 187 EE RL++F ++P S L+ AGF++TG+ DTV+CFSC ++ W+ GD H Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217 Query: 188 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 243 K P C F+ QS S + QY ++ Y G + +HF + Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQGYEGFVHVTGEHFV--------KSW 258 Query: 244 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 303 + R +V + Y + +EE R+ F++WP + + L AG +YTG D V+ Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVR 314 Query: 304 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 360 CF CGG L+ W D +H + FP C F+ ++S ++ + S P +T Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370 Query: 361 PRNPSMADYEA 371 R + D A Sbjct: 371 TRESNHGDAAA 381
Score = 73.2 bits (178), Expect = 2e-12 Identities = 51/154 (33%), Positives = 69/154 (44%), Gaps = 27/154 (17%) Query: 127 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 186 F E R+ F ++P SPV L RAGF YTG+ D VRCFSC +++W GD + Sbjct: 275 FANEELRMDMFKDWPQESPVGVEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334 Query: 187 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 241 H K P C F+ L++SA E + +AL +ET H Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHG 377 Query: 242 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQ 275 D VVD+ R+ A + +EAR S Q Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQ 406
>gi|12643314|sp|Q9JIB6|BIRF_MOUSE Baculoviral IAP repeat-containing protein 1f (Neuronal apoptosis inhibitory protein 6) Length = 1403 Score = 162 bits (409), Expect = 3e-39 Identities = 112/356 (31%), Positives = 160/356 (44%), Gaps = 66/356 (18%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 185 E RLKTF ++ + + +A AGF +TG V+CF C + +G+S + Sbjct: 60 EAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 245 RH+K+ P C F+ G + N G+Y + + P + +L Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149 Query: 246 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 304 R G+ + EEARL+SF++WP YAH T PR L++AG +TG D VQC Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQC 197 Query: 305 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS 349 F CGG L NWE D W EH + FP C F+ + +++ E S Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQDYEGFVHVTGEHFVKS 257 Query: 350 -SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFH 406 R P + + + E R+ F W V E L RAGF+ G+ D V+CF Sbjct: 258 WVRRELPMVSAYCNDSVFTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVRCFS 317 Query: 407 CGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTE 461 CGG L W +DP E H K++P C +L K E I + ++L E T E Sbjct: 318 CGGCLEKWAEGDDPMEDHIKFFPECVFLQTLKSSAEVIPTLQSQYALPEATETTRE 373
Score = 131 bits (329), Expect = 5e-30 Identities = 83/248 (33%), Positives = 128/248 (51%), Gaps = 30/248 (12%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 315 N M SE RLK+F+++ + TP+E+A+AG Y+TG+ VQCFCC G L+ Sbjct: 54 NSQMRSEAKRLKTFESYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112 Query: 316 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 374 P +R H++ P C F+ G+++ NI V S P + EAR+ Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164 Query: 375 TFGTW---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGC 431 +F W + + L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C Sbjct: 165 SFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKC 224 Query: 432 KYLLEQKGQE----YINNIH-LTHSLEECLVRT--TEKTPSLTRRIDDTIFQNPMVQEAI 484 ++L +K E YI + H E V++ + P ++ +D++F N E + Sbjct: 225 EFLQSKKSSEEIAQYIQDYEGFVHVTGEHFVKSWVRRELPMVSAYCNDSVFTN----EEL 280 Query: 485 RMGFSFKD 492 RM FKD Sbjct: 281 RMDM-FKD 287
Score = 112 bits (279), Expect = 4e-24 Identities = 74/251 (29%), Positives = 117/251 (46%), Gaps = 35/251 (13%) Query: 129 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 187 EE RL++F ++P S L+ AGF++TG+ DTV+CFSC ++ W+ GD H Sbjct: 158 EEEARLESFEDWPFYAHGTSPRALSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217 Query: 188 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 243 K P C F+ QS S + QY +++Y G + +HF + Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQDYEGFVHVTGEHFV--------KSW 258 Query: 244 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 303 + R +V + Y + +EE R+ F++WP + + L AG +YTG D V+ Sbjct: 259 VRRELPMV----SAYCNDSVFTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVR 314 Query: 304 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAV---SSDRNFPNSTNL 360 CF CGG L+ W D +H + FP C F+ ++S ++ + S P +T Sbjct: 315 CFSCGGCLEKWAEGDDPMEDHIKFFPECVFL----QTLKSSAEVIPTLQSQYALPEATET 370 Query: 361 PRNPSMADYEA 371 R + D A Sbjct: 371 TRESNHDDAAA 381
Score = 71.6 bits (174), Expect = 5e-12 Identities = 51/154 (33%), Positives = 69/154 (44%), Gaps = 27/154 (17%) Query: 127 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 186 F E R+ F ++P SPV L RAGF YTG+ D VRCFSC +++W GD + Sbjct: 275 FTNEELRMDMFKDWPQESPVGFEALVRAGFFYTGKKDIVRCFSCGGCLEKWAEGDDPMED 334 Query: 187 HRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET-----HA 241 H K P C F+ L++SA E + +AL +ET H Sbjct: 335 HIKFFPECVFLQT--LKSSA---------------EVIPTLQSQYALPEATETTRESNHD 377 Query: 242 DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQ 275 D VVD+ R+ A + +EAR S Q Sbjct: 378 DAAAVHSTVVDLG-----RSEAQWFQEARSLSEQ 406
>gi|12643316|sp|Q9QWK5|BIRA_MOUSE Baculoviral IAP repeat-containing protein 1a (Neuronal apoptosis inhibitory protein 1) Length = 1403 Score = 154 bits (389), Expect = 6e-37 Identities = 108/356 (30%), Positives = 162/356 (45%), Gaps = 66/356 (18%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDS----AVG 185 E RLKTF + + + +A AGF +TG V+CF C + +G+S + Sbjct: 60 EAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLIL----FGNSLRKLPIE 115 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLL 245 RH+K+ P C F+ G + N G+Y + + P + +L Sbjct: 116 RHKKLRPECEFLQGKDVGNI-----------GKYDIR----------VKSPEK-----ML 149 Query: 246 RTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQC 304 R G+ + EEARL+SF++WP YAH T PR L++AG +TG D VQC Sbjct: 150 RGGKA------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQC 197 Query: 305 FCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS 349 F CGG L NWE D W EH + FP C F+ + +++ E S Sbjct: 198 FSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNS 257 Query: 350 -SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFH 406 R P + + A+ E R+ TF W + V + L RAG + G+ V+CF Sbjct: 258 WVRRELPMVSAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFS 317 Query: 407 CGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTH-SLEECLVRTTE 461 CGG + +DP ++H K++P C +L K + L+H +L E + T+E Sbjct: 318 CGGCMEKCTEGDDPIQEHNKFFPNCIFLQTPKSSAEVIPALLSHCALPEAMETTSE 373
Score = 129 bits (325), Expect = 2e-29 Identities = 83/248 (33%), Positives = 126/248 (50%), Gaps = 30/248 (12%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCC-----GGKLKNWE 315 N M SE RLK+F+ + + TP+E+A+AG Y+TG+ VQCFCC G L+ Sbjct: 54 NSQMRSEAKRLKTFETYDTFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKL- 112 Query: 316 PCDRAWSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIF 374 P +R H++ P C F+ G+++ NI V S P + EAR+ Sbjct: 113 PIER----HKKLRPECEFLQGKDVGNIGKYDIRVKS----PEKMLRGGKARYHEEEARLE 164 Query: 375 TFGTW---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGC 431 +F W + + L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C Sbjct: 165 SFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEHAKWFPKC 224 Query: 432 KYLLEQKGQE----YINNIH-LTHSLEECLVRT--TEKTPSLTRRIDDTIFQNPMVQEAI 484 ++L +K E YI H E V + + P ++ +D++F N E + Sbjct: 225 EFLQSKKSSEEIAQYIQGYEGFVHVTGEHFVNSWVRRELPMVSAYCNDSVFAN----EEL 280 Query: 485 RMGFSFKD 492 RM +FKD Sbjct: 281 RMD-TFKD 287
Score = 110 bits (275), Expect = 1e-23 Identities = 68/211 (32%), Positives = 103/211 (48%), Gaps = 28/211 (13%) Query: 129 EEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRH 187 EE RL++F ++P S L+ AGF++TG+ DTV+CFSC ++ W+ GD H Sbjct: 158 EEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGSLGNWEEGDDPWKEH 217 Query: 188 RKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLG----SRDHFALDRPSETHADY 243 K P C F+ QS S + QY ++ Y G + +HF + Sbjct: 218 AKWFPKCEFL----------QSKKSSEEIAQY-IQGYEGFVHVTGEHFV--------NSW 258 Query: 244 LLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 303 + R +V + Y + +EE R+ +F++WP + + L AGL+YTG VQ Sbjct: 259 VRRELPMV----SAYCNDSVFANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQ 314 Query: 304 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV 334 CF CGG ++ D EH + FPNC F+ Sbjct: 315 CFSCGGCMEKCTEGDDPIQEHNKFFPNCIFL 345
Score = 67.0 bits (162), Expect = 1e-10 Identities = 29/71 (40%), Positives = 40/71 (56%) Query: 127 FVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGR 186 F E R+ TF ++P SPV+ L RAG YTG+ V+CFSC +++ GD + Sbjct: 275 FANEELRMDTFKDWPHESPVAVDALVRAGLFYTGKKGIVQCFSCGGCMEKCTEGDDPIQE 334 Query: 187 HRKVSPNCRFI 197 H K PNC F+ Sbjct: 335 HNKFFPNCIFL 345
>gi|12643315|sp|Q9QUK4|BIRB_MOUSE Baculoviral IAP repeat-containing protein 1b (Neuronal apoptosis inhibitory protein 2) Length = 1447 Score = 150 bits (380), Expect = 7e-36 Identities = 106/352 (30%), Positives = 155/352 (44%), Gaps = 58/352 (16%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 189 E RLKTF + + +A AGF +TG V+CF C + + + H+K Sbjct: 60 EAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKK 119 Query: 190 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 249 + P C F+ G + N G+Y + + P + +LR + Sbjct: 120 LRPECEFLLGKDVGNI-----------GKYDIR----------VKSPEK-----MLRGDK 153 Query: 250 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT-PRELASAGLYYTGIGDQVQCFCCG 308 + EEARL+SF++WP YAH T PR L++AG +TG D VQCF CG Sbjct: 154 A------------RYHEEEARLESFEDWPFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCG 201 Query: 309 GKLKNWEPCDRAWSEHRRHFPNCFFVLGRN---------------LNIRSESDAVS-SDR 352 G L NWE D W EH + FP C F+ + L++ E S R Sbjct: 202 GCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPEEITQYVQSYEGFLHVTGEHFVNSWVRR 261 Query: 353 NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNK--EQLARAGFYALGEGDKVKCFHCGGG 410 P + + A+ E R+ TF W + E L +AG + G+ D V+CF CGG Sbjct: 262 ELPMVSAYCNDSVFANEELRMDTFKDWPHESPGAVEALVKAGLFYTGKRDIVQCFSCGGC 321 Query: 411 LTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTE 461 + W ++P E H K++P C +L K E I + +L E + T+E Sbjct: 322 MEKWAEGDNPIEDHTKFFPNCVFLQTLKSSAEVIPALQSHCALPEAMETTSE 373
Score = 130 bits (326), Expect = 1e-29 Identities = 81/246 (32%), Positives = 126/246 (51%), Gaps = 26/246 (10%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRA 320 N M SE RLK+F+ + + TP+E+A+AG Y+TG+ VQCFCC L + Sbjct: 54 NSQMRSEAKRLKTFETYDKFRSWTPQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLP 113 Query: 321 WSEHRRHFPNCFFVLGRNL-NIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTW 379 H++ P C F+LG+++ NI V S P + EAR+ +F W Sbjct: 114 IENHKKLRPECEFLLGKDVGNIGKYDIRVKS----PEKMLRGDKARYHEEEARLESFEDW 169 Query: 380 ---IYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLE 436 + + L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C++L Sbjct: 170 PFYAHGTSPRVLSAAGFVFTGKRDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQS 229 Query: 437 QKGQEYINN--------IHLT--HSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRM 486 +K E I +H+T H + + R + P ++ +D++F N E +RM Sbjct: 230 KKSPEEITQYVQSYEGFLHVTGEHFVNSWVRR---ELPMVSAYCNDSVFAN----EELRM 282 Query: 487 GFSFKD 492 +FKD Sbjct: 283 D-TFKD 287
>gi|1170471|sp|P41437|IAP3_NPVOP Apoptosis inhibitor 3 (IAP-3) Length = 268 Score = 145 bits (367), Expect = 2e-34 Identities = 76/207 (36%), Positives = 115/207 (55%), Gaps = 15/207 (7%) Query: 264 MYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSE 323 M ++ ARL ++ NWP L P +A++G YY G GD+V+C C ++ NW D ++ Sbjct: 15 MKNKAARLGTYTNWP-VQFLEPSRMAASGFYYLGRGDEVRCAFCKVEITNWVRGDDPETD 73 Query: 324 HRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV 383 H+R P C FV R+ + DR P + +P A AR+ TF W + Sbjct: 74 HKRWAPQCPFV-------RNNAHDTPHDRAPPARSAAA-HPQYATEAARLRTFAEWPRGL 125 Query: 384 NK--EQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQE 441 + E+LA AGF+ G+GDK +CF C GGL DW+P + PW+QHA+WY C+Y+L KG++ Sbjct: 126 KQRPEELAEAGFFYTGQGDKTRCFCCDGGLKDWEPDDAPWQQHARWYDRCEYVLLVKGRD 185 Query: 442 YINNIHLTHSLEECLVRTTEKTPSLTR 468 ++ + E C+VR + P + R Sbjct: 186 FVQRV----MTEACVVRDADNEPHIER 208
Score = 112 bits (280), Expect = 2e-24 Identities = 69/218 (31%), Positives = 96/218 (44%), Gaps = 47/218 (21%) Query: 133 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 192 RL T+ N+P + S +A +GF Y G GD VRC C + W GD H++ +P Sbjct: 21 RLGTYTNWPV-QFLEPSRMAASGFYYLGRGDEVRCAFCKVEITNWVRGDDPETDHKRWAP 79 Query: 193 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 252 C F+ N+A + + D R + H Y Sbjct: 80 QCPFV-----RNNAHDTPH-----------------DRAPPARSAAAHPQYA-------- 109 Query: 253 ISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLK 312 +E ARL++F WP P ELA AG +YTG GD+ +CFCC G LK Sbjct: 110 -------------TEAARLRTFAEWPRGLKQRPEELAEAGFFYTGQGDKTRCFCCDGGLK 156 Query: 313 NWEPCDRAWSEHRRHFPNCFFVL---GRNLNIRSESDA 347 +WEP D W +H R + C +VL GR+ R ++A Sbjct: 157 DWEPDDAPWQQHARWYDRCEYVLLVKGRDFVQRVMTEA 194
Score = 61.2 bits (147), Expect = 6e-09 Identities = 26/72 (36%), Positives = 38/72 (52%) Query: 126 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 ++ E RL+TFA +P G LA AGF YTG+GD RCF C + W+ D+ Sbjct: 107 QYATEAARLRTFAEWPRGLKQRPEELAEAGFFYTGQGDKTRCFCCDGGLKDWEPDDAPWQ 166 Query: 186 RHRKVSPNCRFI 197 +H + C ++ Sbjct: 167 QHARWYDRCEYV 178
Score = 53.5 bits (127), Expect = 1e-06 Identities = 19/37 (51%), Positives = 25/37 (67%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 +LCKIC+ + FVPCGH+V C +CA V CP+C Sbjct: 219 RLCKICLGAEKTVCFVPCGHVVACGKCAAGVTTCPVC 255
>gi|12643291|sp|Q13075|BIR1_HUMAN Baculoviral IAP repeat-containing protein 1 (Neuronal apoptosis inhibitory protein) Length = 1403 Score = 144 bits (363), Expect = 6e-34 Identities = 116/373 (31%), Positives = 162/373 (43%), Gaps = 64/373 (17%) Query: 130 EFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK 189 E RLKTF + S +A AGF +TG ++CF C + + H++ Sbjct: 60 EAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR 119 Query: 190 VSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQ 249 P+C GF L I +V+N L SR LR G+ Sbjct: 120 FHPDC----GFLLNKDV-----GNIAKYDIRVKN-LKSR----------------LRGGK 153 Query: 250 VVDISDTIYPRNPAMYSEEARLKSFQNWPDYAH-LTPRELASAGLYYTGIGDQVQCFCCG 308 + EEARL SF+NWP Y ++P L+ AG +TG D VQCF CG Sbjct: 154 M------------RYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCG 201 Query: 309 GKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN------IRSESDAVS-SDRNFPNS---T 358 G L NWE D W EH + FP C F+ + + I+S V + +F NS Sbjct: 202 GCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQR 261 Query: 359 NLPR-----NPSMADYEA-RIFTFGTWIY--SVNKEQLARAGFYALGEGDKVKCFHCGGG 410 LP N S+ YE R+ +F W +V LA+AG + G D V+CF CGG Sbjct: 262 ELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGC 321 Query: 411 LTDWKPSEDPWEQHAKWYPGCKYLLEQKGQ-EYINNIHLTHSLEECLVRTTEKTPSLTRR 469 L W+ +DP + H + +P C +L K E ++ L E L T+E Sbjct: 322 LEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSRGELCELLETTSESN------ 375 Query: 470 IDDTIFQNPMVQE 482 ++D+I P+V E Sbjct: 376 LEDSIAVGPIVPE 388
Score = 129 bits (323), Expect = 2e-29 Identities = 66/188 (35%), Positives = 100/188 (53%), Gaps = 10/188 (5%) Query: 261 NPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRA 320 N M SE RLK+F + Y+ P+E+A+AG Y+TG+ +QCFCC L Sbjct: 54 NSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLP 113 Query: 321 WSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSM--ADYEARIFTFGT 378 +H+R P+C F+L +++ + D N + R M + EAR+ +F Sbjct: 114 IEDHKRFHPDCGFLLNKDV-----GNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRN 168 Query: 379 WIYSVNKEQ---LARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLL 435 W + V L+ AGF G+ D V+CF CGG L +W+ +DPW++HAKW+P C++L Sbjct: 169 WPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLR 228 Query: 436 EQKGQEYI 443 +K E I Sbjct: 229 SKKSSEEI 236
Score = 124 bits (311), Expect = 7e-28 Identities = 89/272 (32%), Positives = 129/272 (47%), Gaps = 54/272 (19%) Query: 127 FVEEFNRLKTFANFP-SGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 + EE RL +F N+P +S L+ AGF++TG+ DTV+CFSC + W+ GD Sbjct: 156 YQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWK 215 Query: 186 RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRD----HFA---LDRPSE 238 H K P C F+ +S S + QY +++Y G D HF + R Sbjct: 216 EHAKWFPKCEFL----------RSKKSSEEITQY-IQSYKGFVDITGEHFVNSWVQRELP 264 Query: 239 THADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGI 298 + Y +D+I+ EE RL SF++WP + + LA AGL+YTGI Sbjct: 265 MASAY---------CNDSIFAY------EELRLDSFKDWPRESAVGVAALAKAGLFYTGI 309 Query: 299 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDA----------- 347 D VQCF CGG L+ W+ D +H R FPNC F+ N++S ++ Sbjct: 310 KDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFL----QNMKSSAEVTPDLQSRGELC 365 Query: 348 ----VSSDRNFPNSTNL-PRNPSMADYEARIF 374 +S+ N +S + P P MA EA+ F Sbjct: 366 ELLETTSESNLEDSIAVGPIVPEMAQGEAQWF 397
>gi|1170470|sp|P41436|IAP_GVCP Apoptosis inhibitor IAP Length = 275 Score = 131 bits (330), Expect = 4e-30 Identities = 68/218 (31%), Positives = 113/218 (51%), Gaps = 7/218 (3%) Query: 267 EEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRR 326 EE RL +F+ WP + L+P +A G YY G D+V+C C ++ W+ + ++H++ Sbjct: 7 EEVRLNTFEKWP-VSFLSPETMAKNGFYYLGRSDEVRCAFCKVEIMRWKEGEDPAADHKK 65 Query: 327 HFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNK- 385 P C FV G ++ + + ++ P +P A AR+ +F W + + Sbjct: 66 WAPQCPFVKGIDVCGSIVTTNNIQNTTTHDTIIGPAHPKYAHEAARVKSFHNWPRCMKQR 125 Query: 386 -EQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYIN 444 EQ+A AGF+ G GD KCF+C GGL DW+P + PWEQH +W+ C Y+ KG++Y+ Sbjct: 126 PEQMADAGFFYTGYGDNTKCFYCDGGLKDWEPEDVPWEQHVRWFDRCAYVQLVKGRDYVQ 185 Query: 445 NIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQE 482 + E C++ T S + + I + + +E Sbjct: 186 KV----ITEACVLPGENTTVSTAAPVSEPIPETKIEKE 219
Score = 119 bits (299), Expect = 1e-26 Identities = 70/203 (34%), Positives = 92/203 (45%), Gaps = 38/203 (18%) Query: 133 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 192 RL TF +P S +S T+A+ GF Y G D VRC C + RW+ G+ H+K +P Sbjct: 10 RLNTFEKWPV-SFLSPETMAKNGFYYLGRSDEVRCAFCKVEIMRWKEGEDPAADHKKWAP 68 Query: 193 NCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVD 252 C F+ G + GS + + TH Sbjct: 69 QCPFVKGI----------------------DVCGSIVTTNNIQNTTTH------------ 94 Query: 253 ISDTIY-PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKL 311 DTI P +P E AR+KSF NWP P ++A AG +YTG GD +CF C G L Sbjct: 95 --DTIIGPAHPKYAHEAARVKSFHNWPRCMKQRPEQMADAGFFYTGYGDNTKCFYCDGGL 152 Query: 312 KNWEPCDRAWSEHRRHFPNCFFV 334 K+WEP D W +H R F C +V Sbjct: 153 KDWEPEDVPWEQHVRWFDRCAYV 175
Score = 65.9 bits (159), Expect = 3e-10 Identities = 26/50 (52%), Positives = 34/50 (68%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS 601 KLCKIC + FVPCGH+V C +CA +VDKCPMC ++T K++ S Sbjct: 226 KLCKICYVEECIVCFVPCGHVVACAKCALSVDKCPMCRKIVTSVLKVYFS 275
Score = 50.1 bits (118), Expect = 2e-05 Identities = 22/72 (30%), Positives = 35/72 (48%) Query: 126 EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 185 ++ E R+K+F N+P +A AGF YTG GD +CF C + W+ D Sbjct: 104 KYAHEAARVKSFHNWPRCMKQRPEQMADAGFFYTGYGDNTKCFYCDGGLKDWEPEDVPWE 163 Query: 186 RHRKVSPNCRFI 197 +H + C ++ Sbjct: 164 QHVRWFDRCAYV 175
>gi|2497243|sp|Q24306|IAP1_DROME Apoptosis 1 inhibitor (Inhibitor of apoptosis 1) (dIAP1) (Thread protein) Length = 438 Score = 128 bits (321), Expect = 5e-29 Identities = 78/251 (31%), Positives = 119/251 (47%), Gaps = 38/251 (15%) Query: 360 LPRNPSMADYEARIFTFGTWIYSVNKE--QLARAGFYALGEGDKVKCFHCGGGLTDWKPS 417 P+ P A AR+ TF W ++ ++ QLA AGF+ G GD+V+CF CGGGL DW + Sbjct: 217 FPQYPEYAIETARLRTFEAWPRNLKQKPHQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDN 276 Query: 418 EDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQN 477 ++PWEQHA W C+++ KGQ YI+ + + + L E++ S+ DT+ Sbjct: 277 DEPWEQHALWLSQCRFVKLMKGQLYIDTV----AAKPVLAEEKEESTSIG---GDTVAST 329 Query: 478 PMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLV-------NAQKDSMQDES 530 +E + S ++ +SG S+ A + A + S Sbjct: 330 QASEEEQQTSLSSEE---------AVSGDVAPSVAPTAATRIFNKIVEATAVATPSTNSS 380 Query: 531 SQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYT 590 TS+ +E KLCKIC F+PCGH+V C +CA +V KCP+C Sbjct: 381 GSTSIPEE-------------KLCKICYGAEYNTAFLPCGHVVACAKCASSVTKCPLCRK 427 Query: 591 VITFKQKIFMS 601 T +++ S Sbjct: 428 PFTDVMRVYFS 438
Score = 108 bits (271), Expect = 3e-23 Identities = 84/289 (29%), Positives = 121/289 (41%), Gaps = 56/289 (19%) Query: 92 ALEKVDKSYFQEKMTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTL 151 A ++VD + ++ N+ ++ D+N+EE RLKTF ++P + L Sbjct: 15 AFDQVDNNTNATQLFKNNINKTRM---NDLNREE------TRLKTFTDWPL-DWLDKRQL 64 Query: 152 ARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRF----------INGFY 201 A+ G +T GD V+CF C + W+ D V H++ SPNC IN Sbjct: 65 AQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEA 124 Query: 202 LEN----------SATQST---------------NSGIQNGQYKVENYLGSRDHFALDRP 236 L+ A ST + IQ+ N GS A +P Sbjct: 125 LDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIGMNAVNAAGSVTGTAAPQP 184 Query: 237 S---ETHA--------DYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTP 285 THA D T + S +P+ P E ARL++F+ WP P Sbjct: 185 RVTVATHASTATQATGDVQPETCRPSAASGNYFPQYPEYAIETARLRTFEAWPRNLKQKP 244 Query: 286 RELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFV 334 +LA AG +YTG+GD+V+CF CGG L +W D W +H C FV Sbjct: 245 HQLAEAGFFYTGVGDRVRCFSCGGGLMDWNDNDEPWEQHALWLSQCRFV 293
Score = 69.3 bits (168), Expect = 2e-11 Identities = 38/90 (42%), Positives = 53/90 (58%), Gaps = 4/90 (4%) Query: 267 EEARLKSFQNWP-DYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHR 325 EE RLK+F +WP D+ L R+LA G+Y+T GD+V+CF CG ++ WE D+ EH+ Sbjct: 44 EETRLKTFTDWPLDW--LDKRQLAQTGMYFTHAGDKVKCFFCGVEIGCWEQEDQPVPEHQ 101 Query: 326 RHFPNCFFVLGRNLNIRSESDAVSSDRNFP 355 R PNC + R N +A + DR P Sbjct: 102 RWSPNCPLLRRRTTN-NVPINAEALDRILP 130
Score = 62.8 bits (151), Expect = 2e-09 Identities = 34/94 (36%), Positives = 47/94 (50%), Gaps = 5/94 (5%) Query: 346 DAVSSDRN----FPNSTNLPRNPSMADYEARIFTFGTWIYS-VNKEQLARAGFYALGEGD 400 D V ++ N F N+ N R + E R+ TF W ++K QLA+ G Y GD Sbjct: 17 DQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGD 76 Query: 401 KVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYL 434 KVKCF CG + W+ + P +H +W P C L Sbjct: 77 KVKCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLL 110
>gi|21759008|sp|Q96CA5|BIR7_HUMAN Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin) Length = 298 Score = 98.6 bits (244), Expect = 4e-20 Identities = 42/93 (45%), Positives = 59/93 (63%), Gaps = 2/93 (2%) Query: 361 PRNPSMADYEARIFTFGTWIYS--VNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSE 418 P P M E R+ +F W + V E LA AGF+ G DKV+CF C GGL WK + Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138 Query: 419 DPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHS 451 DPW +HAKW+P C++LL KG+++++++ THS Sbjct: 139 DPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHS 171
Score = 84.0 bits (206), Expect = 9e-16 Identities = 37/77 (48%), Positives = 51/77 (66%) Query: 259 PRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCD 318 P P M SEE RL SF +WP A + P LA+AG ++TG D+V+CF C G L++W+ D Sbjct: 79 PAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGD 138 Query: 319 RAWSEHRRHFPNCFFVL 335 W+EH + FP+C F+L Sbjct: 139 DPWTEHAKWFPSCQFLL 155
Score = 60.1 bits (144), Expect = 1e-08 Identities = 26/65 (40%), Positives = 37/65 (56%) Query: 133 RLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSP 192 RL +F ++P + V LA AGF +TG D VRCF C+ + W+ GD H K P Sbjct: 90 RLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFP 149 Query: 193 NCRFI 197 +C+F+ Sbjct: 150 SCQFL 154
>gi|33302608|sp|P47732|ZFP_IRV6 Zinc finger protein Length = 208 Score = 78.2 bits (191), Expect = 5e-14 Identities = 57/229 (24%), Positives = 87/229 (37%), Gaps = 64/229 (27%) Query: 362 RNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSED 419 +N A Y+ R+ +F W + +KEQL+RAGF L GD+V+CF+C L +WK S++ Sbjct: 30 KNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRSDN 89 Query: 420 PWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPM 479 P+E+H K H CL + + + + ++ FQNP+ Sbjct: 90 PFEEHKK--------------------HTQDLKINCLFVKSIEFDNFVKNHSESCFQNPI 129 Query: 480 VQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEI 539 +N D QD L + Sbjct: 130 TNN------------------------------------INQDLDHNQDLDHNQDLDQNS 153 Query: 540 STXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 +T CKIC I V +PCGH +C +C + CP+C Sbjct: 154 TTSDCDVLT-----CKICFTNKITKVLIPCGH-SSCYECVFKLQTCPIC 196
Score = 70.1 bits (170), Expect = 1e-11 Identities = 35/79 (44%), Positives = 44/79 (55%), Gaps = 4/79 (5%) Query: 260 RNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDR 319 +N S + RL SFQNWP + +L+ AG Y IGDQVQCF C KLK W+ D Sbjct: 30 KNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRSDN 89 Query: 320 AWSEHRRHFP----NCFFV 334 + EH++H NC FV Sbjct: 90 PFEEHKKHTQDLKINCLFV 108
Score = 56.2 bits (134), Expect = 2e-07 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 4/100 (4%) Query: 121 INKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYG 180 I K F RL +F N+P S L+RAGF+Y GD V+CF C + W+ Sbjct: 28 IIKNLPFASYDERLNSFQNWPIQLLPSKEQLSRAGFIYLNIGDQVQCFYCDLKLKEWKRS 87 Query: 181 DSAVGRHRK----VSPNCRFINGFYLENSATQSTNSGIQN 216 D+ H+K + NC F+ +N + S QN Sbjct: 88 DNPFEEHKKHTQDLKINCLFVKSIEFDNFVKNHSESCFQN 127
>gi|2497245|sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 (IAP-1) Length = 275 Score = 77.4 bits (189), Expect = 9e-14 Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 12/183 (6%) Query: 270 RLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFP 329 R SF+++P L G YT + D V C CG +KNW D H P Sbjct: 27 RHNSFEDYPIDNDAFVNSLIVNGFRYTHVDDAVVCEYCGVVIKNWRENDVVEFVHATLSP 86 Query: 330 NCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPS-----MADYEARIFTFGTWIYSVN 384 C + N ++++ + D + P P +A AR TF W ++N Sbjct: 87 YCVYA-----NKIAQNEQFAEDISTDAVVVSPGKPRCVYNRLAHPSARRATFDHWPAALN 141 Query: 385 --KEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEY 442 +A AG + GD+ CF C + DW P +DPW++HA P C +++ KG + Sbjct: 142 ALTHDIAEAGMFHTMLGDETACFFCDCRVRDWLPGDDPWQRHALANPQCYFVVCVKGDGF 201 Query: 443 INN 445 N+ Sbjct: 202 CNS 204
Score = 75.9 bits (185), Expect = 3e-13 Identities = 50/216 (23%), Positives = 87/216 (40%), Gaps = 35/216 (16%) Query: 120 DINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQY 179 + + E F R +F ++P + ++L GF YT D V C C + W+ Sbjct: 14 ETSAERVFGMLIERHNSFEDYPIDNDAFVNSLIVNGFRYTHVDDAVVCEYCGVVIKNWRE 73 Query: 180 GDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET 239 D H +SP C + N + + FA D ++ Sbjct: 74 NDVVEFVHATLSPYCVY-------------------------ANKIAQNEQFAEDISTDA 108 Query: 240 HADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIG 299 ++ G+ +Y R + AR +F +WP + ++A AG+++T +G Sbjct: 109 ---VVVSPGK----PRCVYNR---LAHPSARRATFDHWPAALNALTHDIAEAGMFHTMLG 158 Query: 300 DQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVL 335 D+ CF C ++++W P D W H P C+FV+ Sbjct: 159 DETACFFCDCRVRDWLPGDDPWQRHALANPQCYFVV 194
Score = 45.8 bits (107), Expect = 3e-04 Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 1/49 (2%) Query: 554 CKICMDRNIAIVFVPCGHLVTCKQCAEAVD-KCPMCYTVITFKQKIFMS 601 CK+C++R V +PC H C QC A+D KCP C + KIF++ Sbjct: 227 CKVCLERQRDAVLLPCRHFCVCMQCYFALDGKCPTCRQDVADFIKIFVT 275
>gi|12585192|sp|Q9NR09|BIR6_HUMAN Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon) Length = 4829 Score = 75.9 bits (185), Expect = 2e-13 Identities = 45/123 (36%), Positives = 57/123 (46%), Gaps = 20/123 (16%) Query: 264 MYSEEARLKSFQNWPD--YAHLTPRELASAGLYY---TGIGDQVQCFCCGGKLKNWEPCD 318 MYSE R ++F +WP Y P +A AG Y+ + D+ CF C L WEP D Sbjct: 255 MYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTD 314 Query: 319 RAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSM---ADYEARIFT 375 WSEH RH PNC FV G + +N P S L +P+ D RI Sbjct: 315 EPWSEHERHSPNCPFVKGEH------------TQNVPLSVTLATSPAQFPCTDGTDRISC 362 Query: 376 FGT 378 FG+ Sbjct: 363 FGS 365
Score = 50.4 bits (119), Expect = 1e-05 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 11/85 (12%) Query: 375 TFGTWIYS----VNKEQLARAGFY---ALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKW 427 TF +W + + +A+AGFY A D+ CF C L W+P+++PW +H + Sbjct: 264 TFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERH 323 Query: 428 YPGCKYLLEQKGQEYINNIHLTHSL 452 P C ++ KG E+ N+ L+ +L Sbjct: 324 SPNCPFV---KG-EHTQNVPLSVTL 344
Score = 44.7 bits (104), Expect = 6e-04 Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 5/80 (6%) Query: 130 EFNRLKTFANFPSGSP--VSASTLARAGFLY---TGEGDTVRCFSCHAAVDRWQYGDSAV 184 E NR +TF ++P +A+AGF + + D CF+C + W+ D Sbjct: 258 EANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPW 317 Query: 185 GRHRKVSPNCRFINGFYLEN 204 H + SPNC F+ G + +N Sbjct: 318 SEHERHSPNCPFVKGEHTQN 337
>gi|1170468|sp|P41435|IAP1_NPVAC Apoptosis inhibitor 1 (IAP-1) Length = 286 Score = 74.3 bits (181), Expect = 7e-13 Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 20/193 (10%) Query: 270 RLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFP 329 R SF+N+P L G Y + D V C C ++KNW + H P Sbjct: 32 RHSSFENYPIENTAFINSLIVNGFKYNQVDDHVVCEYCEAEIKNWSEDECIEYAHVTLSP 91 Query: 330 NCFFV--------LGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIY 381 C + G N+ I +AV P M++ ++R+ TF + Sbjct: 92 YCAYANKIAERESFGDNITI----NAVLVKEGKPKCVY----RCMSNLQSRMDTFVNFWP 143 Query: 382 SVNKE---QLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQK 438 + ++ +A AG + G GD+ CF C + DW +ED W++HA P C ++L K Sbjct: 144 AALRDMITNIAEAGLFYTGRGDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFVLSVK 203 Query: 439 GQEYI-NNIHLTH 450 G+E+ N+I +TH Sbjct: 204 GKEFCQNSITVTH 216
Score = 67.4 bits (163), Expect = 8e-11 Identities = 54/217 (24%), Positives = 83/217 (38%), Gaps = 36/217 (16%) Query: 120 DINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQY 179 D E F R +F N+P + ++L GF Y D V C C A + W Sbjct: 19 DNTAEHVFDMLIERHSSFENYPIENTAFINSLIVNGFKYNQVDDHVVCEYCEAEIKNWSE 78 Query: 180 GDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSET 239 + H +SP C + N + R+ F + T Sbjct: 79 DECIEYAHVTLSPYCAY-------------------------ANKIAERESFG---DNIT 110 Query: 240 HADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQN-WPDYAHLTPRELASAGLYYTGI 298 L++ G+ +Y M + ++R+ +F N WP +A AGL+YTG Sbjct: 111 INAVLVKEGK----PKCVY---RCMSNLQSRMDTFVNFWPAALRDMITNIAEAGLFYTGR 163 Query: 299 GDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVL 335 GD+ CF C +++W + W H P C+FVL Sbjct: 164 GDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFVL 200
Score = 52.0 bits (123), Expect = 4e-06 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 10/105 (9%) Query: 97 DKSYFQEKMTFNSF---EGSKTCVPADINKEEEFVEEFNRLKTFANF-PSGSPVSASTLA 152 ++ F + +T N+ EG CV ++ + +R+ TF NF P+ + +A Sbjct: 101 ERESFGDNITINAVLVKEGKPKCVYRCMSNLQ------SRMDTFVNFWPAALRDMITNIA 154 Query: 153 RAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFI 197 AG YTG GD CF C V W + RH +P C F+ Sbjct: 155 EAGLFYTGRGDETVCFFCDCCVRDWHTNEDTWQRHAAENPQCYFV 199
Score = 44.7 bits (104), Expect = 7e-04 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 554 CKICMDRNIAIVFVPCGHLVTCKQCAEAVD-KCPMCYTVITFKQKIFM 600 CK+C++R V +PC H C QC +D KCP C +T KIF+ Sbjct: 238 CKVCLERQRDAVLMPCRHFCVCVQCYFGLDQKCPTCRQDVTDFIKIFV 285
>gi|3183409|sp|O14064|BIR1_SCHPO Bir1 protein (Chromosome segregation protein cut17) Length = 997 Score = 67.4 bits (163), Expect = 9e-11 Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 34/190 (17%) Query: 264 MYSEEARLKSFQN--WPDYAHLTPRELASAGLYYTGIG--------DQVQCFCCGGKLKN 313 M + RL +FQ WP A TP LA+ G YY I D V C+ C + Sbjct: 19 MCNYSKRLDTFQKKKWPR-AKPTPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYD 77 Query: 314 WEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARI 373 WE D EH H P+C + + S +N PN P+ ++ + Sbjct: 78 WEDDDDPLKEHITHSPSCPWAY------------ILSSKNNPNQN--PQAAALTKCREQT 123 Query: 374 FTFGTWIYSVNKEQ------LARAGFY---ALGEGDKVKCFHCGGGLTDWKPSEDPWEQH 424 F W Y+ + +A +GF D C +C L DW+P +DP+ +H Sbjct: 124 FVDKVWPYTNRPDYHCEPSVMAASGFVYNPTADAKDAAHCLYCDINLHDWEPDDDPYTEH 183 Query: 425 AKWYPGCKYL 434 + C + Sbjct: 184 KRRRADCVFF 193
Score = 52.8 bits (125), Expect = 2e-06 Identities = 52/221 (23%), Positives = 78/221 (35%), Gaps = 59/221 (26%) Query: 133 RLKTF--ANFPSGSPVSASTLARAGFLYTGEG--------DTVRCFSCHAAVDRWQYGDS 182 RL TF +P P + TLA GF Y D V C+ C + W+ D Sbjct: 25 RLDTFQKKKWPRAKP-TPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYDWEDDDD 83 Query: 183 AVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHAD 242 + H SP+C + +N+ Q+ + AL + E Sbjct: 84 PLKEHITHSPSCPWAYILSSKNNPNQNPQAA------------------ALTKCREQ--- 122 Query: 243 YLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQ- 301 D ++P + N PDY H P +A++G Y D Sbjct: 123 ---------TFVDKVWP--------------YTNRPDY-HCEPSVMAASGFVYNPTADAK 158 Query: 302 --VQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLN 340 C C L +WEP D ++EH+R +C F ++ N Sbjct: 159 DAAHCLYCDINLHDWEPDDDPYTEHKRRRADCVFFTWKDPN 199
Score = 38.5 bits (88), Expect = 0.050 Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 13/86 (15%) Query: 366 MADYEARIFTFGTWIYSVNK---EQLARAGFY--ALGEG------DKVKCFHCGGGLTDW 414 M +Y R+ TF + K E LA GFY + E D V C+ C DW Sbjct: 19 MCNYSKRLDTFQKKKWPRAKPTPETLATVGFYYNPISESNSEERLDNVTCYMCTKSFYDW 78 Query: 415 KPSEDPWEQHAKWYPGC--KYLLEQK 438 + +DP ++H P C Y+L K Sbjct: 79 EDDDDPLKEHITHSPSCPWAYILSSK 104
>gi|12585184|sp|Q9JHY7|BIR5_RAT Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) Length = 142 Score = 59.3 bits (142), Expect = 3e-08 Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 264 MYSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCD 318 MY ++ R+ +F+NWP + TP +A AG + D QCF C +L+ WEP D Sbjct: 12 MYLKDHRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDD 71 Query: 319 RAWSEHRRHFPNCFFV 334 EHR+H P C F+ Sbjct: 72 NPIEEHRKHSPGCAFL 87
Score = 55.8 bits (133), Expect = 3e-07 Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 7/92 (7%) Query: 357 STNLPRNPSMADYEARIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGG 409 +T LP M + RI+TF W + S E++A AGF E D +CF C Sbjct: 3 ATALPPIWQMYLKDHRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFK 62 Query: 410 GLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQE 441 L W+P ++P E+H K PGC +L +K E Sbjct: 63 ELEGWEPDDNPIEEHRKHSPGCAFLTVKKQVE 94
Score = 45.8 bits (107), Expect = 3e-04 Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 5/71 (7%) Query: 132 NRLKTFANFPSGSPVSAST--LARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 186 +R+ TF N+P S + +A AGF++ E D +CF C ++ W+ D+ + Sbjct: 17 HRIYTFKNWPFLEDCSCTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEE 76 Query: 187 HRKVSPNCRFI 197 HRK SP C F+ Sbjct: 77 HRKHSPGCAFL 87
>gi|6647548|sp|O70201|BIR5_MOUSE Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) (TIAP) Length = 140 Score = 57.4 bits (137), Expect = 1e-07 Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 5/81 (6%) Query: 259 PRNPAMYSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKN 313 P+ +Y + R+ +F+NWP + TP +A AG + D QCF C +L+ Sbjct: 7 PQIWQLYLKNYRIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEG 66 Query: 314 WEPCDRAWSEHRRHFPNCFFV 334 WEP D EHR+H P C F+ Sbjct: 67 WEPDDNPIEEHRKHSPGCAFL 87
Score = 51.2 bits (121), Expect = 6e-06 Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 7/77 (9%) Query: 372 RIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGGGLTDWKPSEDPWEQH 424 RI TF W + + E++A AGF E D +CF C L W+P ++P E+H Sbjct: 18 RIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEH 77 Query: 425 AKWYPGCKYLLEQKGQE 441 K PGC +L +K E Sbjct: 78 RKHSPGCAFLTVKKQME 94
Score = 45.8 bits (107), Expect = 3e-04 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 133 RLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGRH 187 R+ TF N+P + +A AGF++ E D +CF C ++ W+ D+ + H Sbjct: 18 RIATFKNWPFLEDCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDNPIEEH 77 Query: 188 RKVSPNCRFI 197 RK SP C F+ Sbjct: 78 RKHSPGCAFL 87
>gi|6647543|sp|O15392|BIR5_HUMAN Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin) (Apoptosis inhibitor 4) Length = 142 Score = 50.8 bits (120), Expect = 9e-06 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 5/75 (6%) Query: 265 YSEEARLKSFQNWP--DYAHLTPRELASAGLYYTGIG---DQVQCFCCGGKLKNWEPCDR 319 + ++ R+ +F+NWP + TP +A AG + D QCF C +L+ WEP D Sbjct: 13 FLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDD 72 Query: 320 AWSEHRRHFPNCFFV 334 EH++H C F+ Sbjct: 73 PIEEHKKHSSGCAFL 87
Score = 49.3 bits (116), Expect = 3e-05 Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 9/82 (10%) Query: 364 PSMADYEARIFTFGTWIY----SVNKEQLARAGFYAL---GEGDKVKCFHCGGGLTDWKP 416 P + D+ RI TF W + + E++A AGF E D +CF C L W+P Sbjct: 12 PFLKDH--RISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEP 69 Query: 417 SEDPWEQHAKWYPGCKYLLEQK 438 +DP E+H K GC +L +K Sbjct: 70 DDDPIEEHKKHSSGCAFLSVKK 91
Score = 44.7 bits (104), Expect = 7e-04 Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Query: 132 NRLKTFANFP--SGSPVSASTLARAGFLYT---GEGDTVRCFSCHAAVDRWQYGDSAVGR 186 +R+ TF N+P G + +A AGF++ E D +CF C ++ W+ D + Sbjct: 17 HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEE 76 Query: 187 HRKVSPNCRFIN 198 H+K S C F++ Sbjct: 77 HKKHSSGCAFLS 88
>gi|1170469|sp|P41454|IAP2_NPVAC Probable apoptosis inhibitor 2 (IAP-2) Length = 249 Score = 46.6 bits (109), Expect = 2e-04 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 12/77 (15%) Query: 512 EVLVADLVNAQKDSMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGH 571 E+L ADL+ + L +++S CK+C DR ++ F+PC H Sbjct: 172 EILAADLIPPRLSVKPSAPPAEPLTQQVSE------------CKVCFDREKSVCFMPCRH 219 Query: 572 LVTCKQCAEAVDKCPMC 588 L C +C+ +C +C Sbjct: 220 LAVCTECSRRCKRCCVC 236
Score = 42.4 bits (98), Expect = 0.003 Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 10/76 (13%) Query: 130 EFNRLKTFANFPSG------SPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSA 183 E R K+F +F S V LAR GF Y G+ +RC CH V +++ D A Sbjct: 82 ESMRKKSFTSFKSSRRQFASQSVVVDMLARRGFYYFGKAGHLRCSGCH-IVFKYKSVDDA 140 Query: 184 VGRHRKVSPNCRFING 199 RH++ NC+F+N Sbjct: 141 QRRHKQ---NCKFLNA 153
>gi|34395860|sp|Q86B79|UNK_DROME Unkempt protein Length = 599 Score = 44.3 bits (103), Expect = 8e-04 Identities = 18/57 (31%), Positives = 26/57 (45%) Query: 532 QTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 Q+ L+ ++ K C C + N + PC HL C CAE+V +CP C Sbjct: 534 QSKLRTDLEEVDKVLYLENAKKCMKCEENNRTVTLEPCNHLSICNTCAESVTECPYC 590
>gi|732428|sp|P40629|ZEF2_IRV6 Zinc finger protein Length = 145 Score = 42.4 bits (98), Expect = 0.003 Identities = 27/105 (25%), Positives = 43/105 (40%), Gaps = 34/105 (32%) Query: 509 KSLEVLVADLV--------NAQKDSMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDR 560 ++LEV + D+ N ++ Q E T+L K ++ C IC+ Sbjct: 45 QNLEVEIIDITPEIEILNQNEKEKFNQVEDKLTTLSKNLT-------------CIICLTN 91 Query: 561 NIAIVFVPCGHLVTCKQCA-------------EAVDKCPMCYTVI 592 + I+ +PCGHL+ C C+ +KCP C T I Sbjct: 92 QVQILTIPCGHLIMCNPCSLNLNNSVCTRGVNSNYEKCPKCRTPI 136
>gi|2501727|sp|O10324|IAP2_NPVOP Probable apoptosis inhibitor 2 (IAP-2) Length = 236 Score = 40.8 bits (94), Expect = 0.009 Identities = 13/35 (37%), Positives = 21/35 (60%) Query: 554 CKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 CK+C ++ F+PC HLV C +C+ +C +C Sbjct: 189 CKVCFVNEKSVCFLPCRHLVVCAECSPRCKRCCVC 223
>gi|20139692|sp|Q9BY78|RN26_HUMAN RING finger protein 26 Length = 433 Score = 39.7 bits (91), Expect = 0.018 Identities = 15/44 (34%), Positives = 24/44 (54%), Gaps = 7/44 (15%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK-------CPMC 588 K C IC D++ ++ +PC HL C+ C E + + CP+C Sbjct: 378 KKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLC 421
>gi|32129904|sp|Q93WF1|PL20_ARATH Probable pectate lyase 20 precursor Length = 417 Score = 39.3 bits (90), Expect = 0.028 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 10/99 (10%) Query: 272 KSFQNWPDYAHLTPRELASA---GLYYTGIGDQVQCFCC--GGKLKNWEPCDRAWSEHRR 326 +S + W ++A P E+A+ + + ++ F C G + + CDR W R+ Sbjct: 27 RSNETWHEHAVENPEEVAAMVDMSIRNSTARRRLGYFSCSTGNPIDDCWRCDRRWQSRRK 86 Query: 327 HFPNCFFVLGRN-LNIRSESDAVSSDRNFPNSTNLPRNP 364 H NC GRN + R V SD PN N P NP Sbjct: 87 HLANCAIGFGRNAIGGRDGRYYVVSD---PNDDN-PVNP 121
>gi|44887777|sp|Q8BMJ7|CGF1_MOUSE Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein) Length = 332 Score = 38.1 bits (87), Expect = 0.054 Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 521 AQKDSMQDESSQTSLQKEI--STXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQC 578 + +S +D S + SL +++ + + C +C + + V +PC H C C Sbjct: 239 SNDESPEDRSVEQSLLEKVGLAGNDGDPVEESSRDCVVCQNGGVNWVLLPCRHACLCDSC 298 Query: 579 AEAVDKCPMC 588 +CPMC Sbjct: 299 VRYFKQCPMC 308
>gi|44887778|sp|Q99675|CGF1_HUMAN Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein) Length = 332 Score = 38.1 bits (87), Expect = 0.061 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 K C +C + + V +PC H C C + +CPMC Sbjct: 272 KDCVVCQNGTVNWVLLPCRHTCLCDGCVKYFQQCPMC 308
>gi|44887774|sp|P97587|CGF1_RAT Cell growth regulator with RING finger domain 1 (Cell growth regulatory gene 19 protein) Length = 332 Score = 36.6 bits (83), Expect = 0.17 Identities = 13/37 (35%), Positives = 18/37 (48%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMC 588 K C +C + + V +PC H C C +CPMC Sbjct: 272 KDCVVCQNGGVNWVLLPCRHACLCDSCVCYFKQCPMC 308
>gi|34223722|sp|P29503|NEUR_DROME Neuralized protein Length = 754 Score = 36.2 bits (82), Expect = 0.22 Identities = 23/79 (29%), Positives = 30/79 (37%), Gaps = 22/79 (27%) Query: 520 NAQKDSMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCA 579 N KDS+ D+ S S + C IC + I V CGH+ C CA Sbjct: 683 NKWKDSLSDQQSTDSSAE----------------CTICYENPIDSVLYMCGHMCMCYDCA 726 Query: 580 ------EAVDKCPMCYTVI 592 +CP+C VI Sbjct: 727 IEQWRGVGGGQCPLCRAVI 745
>gi|2497248|sp|O11451|IAPL_ASFC3 IAP-like protein p27 Length = 224 Score = 35.4 bits (80), Expect = 0.37 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 8/60 (13%) Query: 257 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 314 + P+ S +AR +SF + DY + ++AGL+YT ++ C+CCG K NW Sbjct: 19 VKPKYVGYSSVDARNQSFAIHDIKDY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 72
>gi|34222692|sp|Q24746|NEUR_DROVI Neuralized protein Length = 747 Score = 35.0 bits (79), Expect = 0.46 Identities = 22/76 (28%), Positives = 29/76 (38%), Gaps = 22/76 (28%) Query: 523 KDSMQDESSQTSLQKEISTXXXXXXXXXXKLCKICMDRNIAIVFVPCGHLVTCKQCA--- 579 KDS+ D+ S S + C IC + I V CGH+ C CA Sbjct: 679 KDSLSDQQSTDSSAE----------------CTICYENPIDSVLYMCGHMCMCYDCAIEQ 722 Query: 580 ---EAVDKCPMCYTVI 592 +CP+C VI Sbjct: 723 WRGVGGGQCPLCRAVI 738
>gi|2497250|sp|O11453|IAPL_ASFM2 IAP-like protein p27 Length = 238 Score = 35.0 bits (79), Expect = 0.47 Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 8/60 (13%) Query: 257 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 314 + P+ S +AR KSF + +Y + ++AGL+YT ++ C+CCG K NW Sbjct: 33 VKPKYVGYSSVDARNKSFAIHDIKNY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 86
>gi|8928035|sp|Q9ULV8|CBLC_HUMAN Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) Length = 474 Score = 35.0 bits (79), Expect = 0.51 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 6/42 (14%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEA-----VDKCPMC 588 +LCKIC + N + PCGHL+ C C A CP C Sbjct: 349 ELCKICAESNKDVKIEPCGHLL-CSCCLAAWQHSDSQTCPFC 389
>gi|8928017|sp|Q13191|CBLB_HUMAN Signal transduction protein CBL-B (SH3-binding protein CBL-B) Length = 982 Score = 34.7 bits (78), Expect = 0.72 Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 552 KLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK-----CPMC 588 +LCKIC + + + PCGHL+ C C A + CP C Sbjct: 371 QLCKICAENDKDVKIEPCGHLM-CTSCLTAWQESDGQGCPFC 411
>gi|32130094|sp|Q87AB6|SYFB_XYLFT Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS) Length = 792 Score = 34.7 bits (78), Expect = 0.72 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 111 EGSKTCVPA---DINKEEEFVEEFNRLKTFANFPSGSPVSASTLA 152 EG + P+ DI EE+ +EE R++ + + P+ PV AS +A Sbjct: 441 EGWRVVAPSRRFDIAIEEDLIEELVRIRGYEHLPTALPVGASHIA 485
>gi|12229991|sp|Q9PFD6|SYFB_XYLFA Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS) Length = 792 Score = 33.9 bits (76), Expect = 1.0 Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 111 EGSKTCVPA---DINKEEEFVEEFNRLKTFANFPSGSPVSASTLA 152 EG + P+ DI EE+ +EE R++ + + P+ P+ AS +A Sbjct: 441 EGWRVVAPSRRFDIAIEEDLIEELVRIRGYEHLPTALPIGASHIA 485
>gi|8472490|sp|O15151|MDM4_HUMAN Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein) Length = 490 Score = 33.9 bits (76), Expect = 1.1 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 6/56 (10%) Query: 552 KLCKICMDR--NIAIVFVPCGHLVTCKQCAEAVDK----CPMCYTVITFKQKIFMS 601 K C +C R + I+ GHLVTC CA + K CP+C I K+F++ Sbjct: 435 KPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIKVFIA 490
>gi|2497249|sp|O11452|IAPL_ASFM1 IAP-like protein p27 Length = 224 Score = 33.9 bits (76), Expect = 1.2 Identities = 24/109 (22%), Positives = 43/109 (39%), Gaps = 21/109 (19%) Query: 384 NKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKG---- 439 N E+ + AG + + + C+ CG +W + P + HA W C ++ G Sbjct: 43 NYEKFSNAGLFYTSPTE-ITCYCCGMKFCNWLYEKHPLQVHAFWSRNCGFMRATLGIIGL 101 Query: 440 -------QEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQ 481 +Y NN E V+ + + +R++D F P +Q Sbjct: 102 KKMIDSYNDYYNN--------EVFVKHKNRVYT-HKRLEDMGFSKPFMQ 141
Score = 33.5 bits (75), Expect = 1.4 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 8/60 (13%) Query: 257 IYPRNPAMYSEEARLKSF--QNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNW 314 + P+ S +AR +SF + +Y + ++AGL+YT ++ C+CCG K NW Sbjct: 19 VKPKYVGYSSVDARNQSFAIHDIKNY-----EKFSNAGLFYTS-PTEITCYCCGMKFCNW 72
Database: Non-redundant SwissProt sequences Posted date: Mar 9, 2004 2:01 PM Number of letters in database: 53,526,777 Number of sequences in database: 145,815 Lambda K H 0.319 0.134 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,564,154 Number of Sequences: 145815 Number of extensions: 551887 Number of successful extensions: 1316 Number of sequences better than 10.0: 13 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1263 Number of HSP's gapped (non-prelim): 34 length of query: 601 length of database: 53,526,777 effective HSP length: 115 effective length of query: 486 effective length of database: 36,758,052 effective search space: 17864413272 effective search space used: 17864413272 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
