CLUSTAL W (1.82) multiple sequence alignment


1_Rattus_norvegicus            ---WDDQKVRQLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQAN-P 46
13_Mus_musculus                ---WDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQAN-P 46
2_Homo_sapiens                 ---WDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQAN-P 46
11_Camelpox_virus              ----ASVHIRMAFLRKVYGILCLQFLLTTATTAVFLYFDCMRKIIQGS-P 45
12_Homo_sapiens                ----ATVHIRMAFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHES-P 45
10_P._falciparum               LNEFSSTKIRHGFIRKVYSILSLQLLLTFGCAALAVLYKPFNAFVLTYYS 50
5_Drosophila_melanogaster      -----DQSIRKGFIRKVYLILMCQLLITFGFVSVFTFSKASQEWVQKN-P 44
7_Drosophila_melanogaster      -----DQSIRRGFIRKVYLILMGQLIVTFGAVALFVYHEGTKTFARNN-M 44
8_Anopheles_gambiae            -----DQSIRRGFIRKVYSILTVQLAITLGFITLFLYHRPTKLWVQNH-P 44
3_Mus_musculus                 AVNWD-KNIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVREN-V 48
4_Rattus_sp.                   SVNWD-KSIRQAFIRKVFLVLTLQLSVTLSTVAIFTFVGEVKGFVRAN-V 48
9_Ovis_aries                   ATNWDDKSIRQAFIRKVFLVLTLQLSVTLSTVAVFTFLGEVKGFVREN-S 49
6_C._elegans                   ---FSDKTVRAAFVRKVFSLVFIMLCIVAAVTVIPWVHDDTMRMVRRN-S 46
                                       :*  *:***: ::   . :.     :                

1_Rattus_norvegicus            GWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSS 96
13_Mus_musculus                GWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSS 96
2_Homo_sapiens                 GWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSS 96
11_Camelpox_virus              VLILASMFVSIGLIFALTLH---RHKHPLNLYLLCGFTLSESLTLASVVT 92
12_Homo_sapiens                ALILLFALGSLGLIFALXLN---RHKYPLNLYLLFGFTLLEALTVAVVVT 92
10_P._falciparum               PLFIVGVLLSLPIMIALACAPHMARKYPSNYFILLSITLGMSLIVTLASA 100
5_Drosophila_melanogaster      ALFWIALAVLIVTMICMACCESVRRKTPLNFIFLFLFTVAESFLLGMVAG 94
7_Drosophila_melanogaster      WLFWVALGVMLVTMLSMACCESVRRQTPTNFIFLGLFTAAQSFLMGVSAT 94
8_Anopheles_gambiae            EMFWIALGVMVVTLISMACCGDVRRKAPMNFIFLTLFTLAQAFLLGVTTA 94
3_Mus_musculus                 WTYYVSYAIFFISLIVLSCCGDFRRKHPWNLVALSILTVSLSYMVGMIAS 98
4_Rattus_sp.                   WTYYVSYAIFFISLIVLSCCGDFRKKHPWNLVALSILTISLSYMVGMIAS 98
9_Ovis_aries                   GPTTLLCRLLRLSHCPQLLWG-LPAEAPLEPCCAVDPDCQLVLHGGHDCQ 98
6_C._elegans                   ALYLGSYVIFFVTYLSLVCCEGVRRKFPVNLIVTGIFTLATSVMTMVISA 96
                                                          . * :                    

1_Rattus_norvegicus            YYNTTSVLLCLGITALVCLSVTIFSFQTKFDFTSCHGVLFVLLMTLFFSG 146
13_Mus_musculus                YYNTTSVLLCLVITALVCLSVTIFSFQTKFDFTSCQGVLFVLLMTLFFSG 146
2_Homo_sapiens                 YYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSG 146
11_Camelpox_virus              FYDVHVVMQAFMLTTAVFLALTAYTLQSKRDFSKLGAGLFVTLWILILSG 142
12_Homo_sapiens                FYDVYIILQAFILTTTVFFGLTVYTLQSKKDFSKFGAGLFALLWILCLSG 142
10_P._falciparum               RTNSEIFFYAFGTTAVVVIGLTIFAFQTKWDFTGWYVFLFMAFLILIVMG 150
5_Drosophila_melanogaster      QFEADEVLMAVGITAAVALGLTLFALQTKYDFTMCGGVLVACLVVFIIFG 144
7_Drosophila_melanogaster      KYAPKEVLMAVGITAAVCLALTIFALQTKYDFTMMGGILIACMVVFLIFG 144
8_Anopheles_gambiae            NFSSQEVMLAVGITAAVCLGLTLFAFQTKWDFTVMGGILFVAVLILMLFG 144
3_Mus_musculus                 FYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFA 148
4_Rattus_sp.                   FYNTEAVIMAVGITTAVCFTVVIFSMQTRYDFTSCMGVLLVSVVVLFIFA 148
9_Ovis_aries                   LLQHRGSHHGCRHHHDRLLHSGHLSMQTRYDFTSCVGVLLVSVVVLILFA 148
6_C._elegans                   HHDANVVLLALAICIGCTFSIVIVASQTKFDLTAHMGYILIISMCFMFFG 146
                                                 :     : *:: *::     :.     : . .

1_Rattus_norvegicus            LLLAILLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGN--RRHSLSP 194
13_Mus_musculus                LLLAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGN--RRHSLSP 194
2_Homo_sapiens                 LILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGN--RRHSLSP 194
11_Camelpox_virus              ----LLRIFVQSETVELVLSAFGALVFCGFIIYDTHSLI------HKLSP 182
12_Homo_sapiens                ----FLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLM------HKLSP 182
10_P._falciparum               ----IIGIFVRSKAFNLVFAGISAFILSISIIVDTQLIIGGKHKKYEFSV 196
5_Drosophila_melanogaster      ----IIAIFIPGKVIGLVYASLGALLFSVYLVYDTQLMLGG-NHKYSISP 189
7_Drosophila_melanogaster      ----IVAIFVKGKIITLVYASIGALLFSVYLIYDTQLMMGG-EHKYSISP 189
8_Anopheles_gambiae            ----LIAIFFPGKTITLVYASAGALIFSIYLVYDTQLMLGG-EHKYSISP 189
3_Mus_musculus                 ----ILCIFIRNRILEIVYASLGALLFTCFLAVDTQLLLGN--KQLSLSP 192
4_Rattus_sp.                   ----ILCIFIRNRILEIVYASLGALLFTCFLAVDTQLLLGN--KQLSLSP 192
9_Ovis_aries                   ----ILCIFIRSRVLEIVYSSLGALLFTCFLAVDTQLLLGN--KQLSLSP 192
6_C._elegans                   LVVVICSMFFKIKFLMMVYALGGALIMMLYLFLDVQMLMGG--KKYEISP 194
                                   .   *     .  * :  .* ::   :  *.: ::       .:* 

1_Rattus_norvegicus            EEYIFGALNIYLDIIYIFTFFLQLFGTNRE- 224
13_Mus_musculus                EEYIFGALNIYLDIIYIFTFFLQLYGTNRE- 224
2_Homo_sapiens                 EEYIFGALNIYLDIIYIFTFFLQLFGTNRE- 224
11_Camelpox_virus              EDYVLASINFYLDIINLFLHLLQLLEVSNKK 213
12_Homo_sapiens                EEYVLAAISLYLDIINLFLHLLRFLEAVNKK 213
10_P._falciparum               DDYIFATLALYMDIINLFLSILSIFSNAE-- 225
5_Drosophila_melanogaster      EEYIFAALNLYLDIINIFMYILTIIGLSRN- 219
7_Drosophila_melanogaster      EEYIFAALNLYLDIINIFMYILTIIGASRD- 219
8_Anopheles_gambiae            EEYIFAALNLYLDIVNIFLYILTIIGASRD- 219
3_Mus_musculus                 EEYVFAALNLYTDIINIFLYILTIIGRAKE- 222
4_Rattus_sp.                   EEYVFAALNLYTDIINIFLYILTIIGRSQGI 223
9_Ovis_aries                   EEYVFAALNLYTDIINIFLYILTIIGRSQGI 223
6_C._elegans                   EEYIFASVQIFIDIVQMFWFLLSLFGSR--- 222
                               ::*::.:: :: **: :*  :* :       


LLEGENDA:
1--> Lifeguard; neural membrane protein 35

2--> Lifeguard; KIAA0950 protein

3--> NMDA receptor glutamate-binding chain; LAG protein

4--> NMDA receptor glutamate-binding subunit

5--> NMDA selective glutamate receptor; CG3814-PA

6--> NMDA receptor associated protein

7--> NMDA1; CG3798-PA

8--> agCP6292

9--> transmembrane protein OTMP

10--> P.falciparum homolog of Drosophila NMDA1 protein, putative

11--> NMDA receptor-like protein; CMLV006

12--> z-protein

13--> lifeguard; Q8K1F6


AMINOÀCIDS:

 Vermell: 
	A (alanina)
	V (valina)
	L (leucina)
	I (isoleucina)
	P (prolina)
	F (fenilalanina)
	M (metionina)
	W (triptofan)
 Verd:
	N (asparagina)
	Q (glutamina)
	S (serina)
	T (treonina)
	Y (tirosina)
	G (glicina)
	C (cisteïna)
	H (histidina)
 Blau:
	D (àcid aspàrtic)
	E (àcid glutàmic)
 Rosa: 
	K (lisina)
	R (arginina)

Les famílies d'aminoàcids estan agrupats segons les característiques de la cadena lateral. 
Així doncs, els que estan en vermell corresponen als aminoàcids no polars (més G i C); 
en verd són els aminoàcids polars sense càrrega (excepte G, C i H); en blau són els àcids;
i, finalment, els de color rosa són els bàsics (més H).