ADH1 emeni ----MCIPTM QWAQVAEKVG GPLVYKQIPV PKPGPDQILV KIRYSGVCHT

ADH1 yeast ----MSIPET QKGVIFYESH GKLEHKDIPV PKPKANELLI NVKYSGVCHT

ADH1 bacst ---------- MKAAVVEQFK KPLQVKEVEK PKISYGEVLV RIKACGVCHT

ADH1 horvu -MATAGKVIK CKAAVAWEAG KPLTMEEVEV APPQAMEVRV KILFTSLCHT

ADH1 soltu MSTTVGQVIR CKAAVAWEAG KPLVMEEVDV APPQKMEVRL KILYTSLCHT

ADH1 human -MSTAGKVIK CKAAVLWELK KPFSIEEVEV APPKAHEVRI KMVAVGICGT

DLHAMMGHWP IPVKMPLVGG HEGAGIVVAK GELVHEFEIG DQAGIKWLNG

DLHAWHGDWP LPVKLPLVGG HEGAGVVVGM GENVKGWKIG DYAGIKWLNG

DLHAAHGDWP VKPKLPLIPG HEGVGVIEEV GPGVTHLKVG DRVGIPWLYS

DVYFWEAKGQ IPM-FPRIFG HEAGGIVESV GEGVTDVAPG DHV-LPVFTG

DVYFWEAKGQ NPV-FPRILG HEAAGIVESV GEGVTELGPG DHV-LPVFTG

DDHVVSGTMV TP--LPVILG HEAAGIVESV GEGVTTVKPG DKV-IPLAIP

SCGECEFCRQ SDDPLCARAQ L--------- ---SGYTVDG ----------

SCMACEYCEL GNESNCPHAD L--------- ---SGYTHDG ----------

ACGHCDYCLS GQETLCERQQ N--------- ---AGYSVDG ----------

ECKECPHCKS AESNMCDLLR INTDRGVMIG DGKSRFSIGG KPIYHFVGTS

ECKDCAHCKS EESNMCSLLR INTDRGVMIN DGQSRFSING KPIYHFVGTS

QCGKCRICKN PESNYCLKND VSNPQGTLQ- DGTSRFTCRR KPIHHFLGIS

TFQQYALGKA SHASKIPAGV PVDAAAPVLC AGITVY-KGL KEAGVRPGQT

SFQQYATADA VQAAHIPQGT DLAQVAPILC AGITVY-KAL KSANLMAGHW

GYAEYCRAAA DYVVKIPDNL SFEEAAPIFC AGVTTY-KAL KVTGAKPGEW

TFSEYTVMHV GCVAKINPEA PLDKVCVLSC GISTGLGASI NVAKPPKGST

TFSEYTVVHV GCVAKINPLA PLDKVCVLSC GISTGLGATL NVAKPTKGSS

TFSQYTVVDE NAVAKIDAAS PLEKVCLIGC GFSTGYGSAV NVAKVTPGST

VAIVGAGGGL GSLAQQYAKA MGIRVVAVDG GDEKRAMCES LGTETYVDFT

VAISGAAGGL GSLAVQYAKA MGYRVLGIDG GEGKEELFRS IGGEVFIDFT

VAIYGIGG-L GHVAVQYAKA MGLNVVAVDL GDEKLELAKQ LGADLVVN-P

VAIFGLGAVG LAAAEGARIA GASRIIGVDL NAVRFEEARK FGCTEFVNPK

VAIFGLGAVG LAAAEGARIA GASRIIGVDL NASRFEQAKK FGVTEFVNPK

CAVFGLGGVG LSAIMGCKAA GAARIIAVDI NKDKFAKAKE LGATECINPQ

KSKDLVADVR HGRGCLGAHA VILLAVSEKP FQQATEYVRS -RGTIVAIGL

KEKDIVGAVL KATDG-GAHG VINVSVSEAA IEASTRYVRA -NGTTVLVGM

KHDDAAQWIK EKVGG--VHA TVVTAVSKAA FESAYKSIRR -GGACVLVGL

DHTKPVQQVL ADMTNGGVDR SVECTGNVNA MIQAFECVHD GWGVAVLVGV

DYSKPVQEVI AEMTDGGVDR SVECTGHIDA MISAFECVHD GWGVAVLVGV

DYKKPIQEVL KEMTDGGVDF SFEVIGRLDT MMASLLCCHE ACGTSVIVGV

PPDAYLKAPV INTVVRMITI KGSYVGNRQD GVEALDFFAR GLIKA-----

PAGAKCCSDV FNQVVKSISI VGSYVGNRAD TREALDFFAR GLVKS-----

PP-EEIPIPI FDTVLNGVKI IGSIVGTRKD LQEALQFAAE GKVKT-----

PHKDAEFKTH PMNFLNERTL KGTFFGNFKP RTDLPNVVEM YMKKELEVEK

PHKEAVFKTH PMNLLNERTL KGTFFGNYKP RSDIPSVVEK YMNKELELEK

PPDSQNLSMN PMLLLTGRTW KGAILGGFKS KECVPKLVAD FMAKKFSLDA

-PFKTAPLKD LPKIYELMEQ GRIAGRYVLE MPE

-PIKVVGLST LPEIYEKMEK GQIVGRYVVD TSK

-IVEVQPLEN INDVFDRMLK GQINGRVVLK VD-

FITHSVPFSE INTAFDLMAK GEGIRCIIRM DN-

FITHTLPFAE INKAFDLMLK GEGLRCIITM ED-

LITHVLPFEK INEGFDLLHS GKSIRTILMF ---