PROSITE

ADH 1

>SW:ADHA_H UMAN P0732 7 ALCOHOL  DEHYDROGEN ASE ALPHA  CHAIN (EC

1.1.1.1).

 STAGKVIKCK AAVLWELKKP FSIEEVEVAP PKAHEVRIKM VAVGICGTDD

HVVSGTMVTP

 LPVILGHEAA GIVESVGEGV TTVKPGDKVI PLAIPQCGKC

RICKNPESNY CLKNDVSNPQ

 GTLQDGTSRF TCRRKPIHHF LGISTFSQYT

VVDENAVAKI DAASPLEKVC LIGCGFSTGY

 GSAVNVAKVT PGSTCAVFGL

GGVGLSAIMG CKAAGAARII AVDINKDKFA KAKELGATEC

 INPQDYKKPI

QEVLKEMTDG GVDFSFEVIG RLDTMMASLL CCHEACGTSV IVGVPPDSQN

LSMNPMLLLT GRTWKGAILG GFKSKECVPK LVADFMAKKF SLDALITHVL PFEKINEGFD

 LLHSGKSIRT ILMF

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     300 - 303  NLSM

>PDOC00004 PS00004 CAMP_PHOSPHO_SITE cAMP- and cGMP-dependent protein kinase phosphorylation site [pattern].

     338 - 341  KKfS

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       82 - 84  TvK

     127 - 129  TsR

     131 - 133  TcR

     310 - 312  TgR

     313 - 315  TwK

     364 - 366  SgK

     367 - 369  SiR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       22 - 25  SieE

       75 - 78  SvgE

     122 - 125  TlqD

     150 - 153  TvvD

     164 - 167  SplE

>PDOC00007 PS00007 TYR_PHOSPHO_SITE Tyrosine kinase phosphorylation site [pattern].

     104 - 110  Knp.Esn.Y

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       44 - 49  GIcgTD

       71 - 76  GIveSV

     173 - 178  GCgfST

     181 - 186  GSavNV

     192 - 197  GStcAV

     202 - 207  GVglSA

     210 - 215  GCkaAG

     236 - 241  GAteCI

     261 - 266  GVdfSF

     316 - 321  GAilGG

     320 - 325  GGfkSK

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       66 - 80  GHEaaGivesvGegV

27 hits with 7 PROSITE entries

ADH 2

>SW:ADHB_H UMAN P0032 5 ALCOHOL  DEHYDROGEN ASE BETA C HAIN (EC 1

.1.1.1).

 STAGKVIKCK AAVLWEVKKP FSIEDVEVAP PKAYEVRIKM VAVGICRTDD

HVVSGNLVTP

 LPVILGHEAA GIVESVGEGV TTVKPGDKVI PLFTPQCGKC

RVCKNPESNY CLKNDLGNPR

 GTLQDGTRRF TCRGKPIHHF LGTSTFSQYT

VVDENAVAKI DAASPLEKVC LIGCGFSTGY

 GSAVNVAKVT PGSTCAVFGL

GGVGLSAVMG CKAAGAARII AVDINKDKFA KAKELGATEC

 INPQDYKKPI

QEVLKEMTDG GVDFSFEVIG RLDTMMASLL CCHEACGTSV IVGVPPASQN

LSINPMLLLT GRTWKGAVYG GFKSKEGIPK LVADFMAKKF SLDALITHVL PFEKINEGFD

 LLHSGKSIRT VLTF

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     300 - 303  NLSI

>PDOC00004 PS00004 CAMP_PHOSPHO_SITE cAMP- and cGMP-dependent protein kinase phosphorylation site [pattern].

     128 - 131  RRfT

     338 - 341  KKfS

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       82 - 84  TvK

     127 - 129  TrR

     131 - 133  TcR

     310 - 312  TgR

     313 - 315  TwK

     364 - 366  SgK

     367 - 369  SiR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       22 - 25  SieD

       75 - 78  SvgE

     122 - 125  TlqD

     150 - 153  TvvD

     164 - 167  SplE

>PDOC00007 PS00007 TYR_PHOSPHO_SITE Tyrosine kinase phosphorylation site [pattern].

     104 - 110  Knp.Esn.Y

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       44 - 49  GIcrTD

       71 - 76  GIveSV

     117 - 122  GNprGT

     173 - 178  GCgfST

     181 - 186  GSavNV

     192 - 197  GStcAV

     202 - 207  GVglSA

     210 - 215  GCkaAG

     236 - 241  GAteCI

     261 - 266  GVdfSF

     293 - 298  GVppAS

     316 - 321  GAvyGG

     320 - 325  GGfkSK

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       66 - 80  GHEaaGivesvGegV

30 hits with 7 PROSITE entries

ADH 3

>SW:ADHG_H UMAN P0032 6 ALCOHOL  DEHYDROGEN ASE GAMMA  CHAIN (EC

1.1.1.1).

 STAGKVIKCK AAVLWELKKP FSIEEVEVAP PKAHEVRIKM VAAGICRSDE

HVVSGNLVTP

 LPVILGHEAA GIVESVGEGV TTVKPGDKVI PLFTPQCGKC

RICKNPESNY CLKNDLGNPR

 GTLQDGTRRF TCSGKPIHHF VGVSTFSQYT

VVDENAVAKI DAASPLEKVC LIGCGFSTGY

 GSAVKVAKVT PGSTCAVFGL

GGVGLSVVMG CKAAGAARII AVDINKDKFA KAKELGATEC

 INPQDYKKPI

QEVLKEMTDG GVDFSFEVIG RLDTMMASLL CCHEACGTSV IVGVPPDSQN

LSINPMLLLT GRTWKGAIFG GFKSKESVPK LVADFMAKKF SLDALITNIL PFEKINEGFD

 LLRSGKSIRT VLTF

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     300 - 303  NLSI

>PDOC00004 PS00004 CAMP_PHOSPHO_SITE cAMP- and cGMP-dependent protein kinase phosphorylation site [pattern].

     128 - 131  RRfT

     338 - 341  KKfS

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       82 - 84  TvK

     127 - 129  TrR

     133 - 135  SgK

     310 - 312  TgR

     313 - 315  TwK

     364 - 366  SgK

     367 - 369  SiR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       22 - 25  SieE

       75 - 78  SvgE

     122 - 125  TlqD

     150 - 153  TvvD

     164 - 167  SplE

>PDOC00007 PS00007 TYR_PHOSPHO_SITE Tyrosine kinase phosphorylation site [pattern].

     104 - 110  Knp.Esn.Y

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       44 - 49  GIcrSD

       71 - 76  GIveSV

     117 - 122  GNprGT

     173 - 178  GCgfST

     192 - 197  GStcAV

     202 - 207  GVglSV

     210 - 215  GCkaAG

     236 - 241  GAteCI

     261 - 266  GVdfSF

     316 - 321  GAifGG

     320 - 325  GGfkSK

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       66 - 80  GHEaaGivesvGegV

28 hits with 7 PROSITE entries

ADH 4

>SW:ADHP_H UMAN P0831 9 ALCOHOL  DEHYDROGEN ASE CLASS  II PI CHAI

N PRECURSOR (EC 1.1. 1.1).

 GTKGKVIKCK AAIAWEAGKP LCIEEVEVAP

PKAHEVRIQI IATSLCHTDA SVIDSKFEGL

 AFPVIVGHEA AGIVESIGPG

VTNVKPGDKV IPLYAPLCRK CKFCLSPLTN LCGKISNLKS

 PASDQQLMED

KTSRFTCKGK PVYHFFGTST FSQYTVVSDI NLAKIDDDAN LERVCLLGCG

FSTGYGAAIN NAKVTPGSTC AVFGLGGVGL SAVMGCKAAG ASRIIGIDIN SEKFVKAKAL

 GATDCLNPRD LHKPIQEVII ELTKGGVDFA LDCAGGSETM KAALDCTTAG

WGSCTFIGVA

 AGSKGLTIFP EELIIGRTIN GTFFGGWKSV DSIPKLVTDY

KNKKFNLDAL VTHTLPFDKI

 SEAFDLMNQG KSVRTILIFG RCQEQFRILS

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     320 - 323  NGTF

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

     132 - 134  TsR

     136 - 138  TcK

     231 - 233  SeK

     279 - 281  TmK

     372 - 374  SvR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       51 - 54  SviD

       55 - 58  SkfE

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       72 - 77  GIveSI

     178 - 183  GCgfST

     186 - 191  GAaiNN

     197 - 202  GStcAV

     207 - 212  GVglSA

     215 - 220  GCkaAG

     226 - 231  GIdiNS

     241 - 246  GAtdCL

     266 - 271  GVdfAL

     275 - 280  GGseTM

     298 - 303  GVaaGS

     321 - 326  GTffGG

     325 - 330  GGwkSV

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       67 - 81  GHEaaGivesiGpgV

22 hits with 5 PROSITE entries

ADH 5

>SW:ADHX_H UMAN P1176 6 ALCOHOL  DEHYDROGEN ASE CLASS  III CHI CH

AIN (EC 1. 1.1.1) (GL UTATHIONE-  DEPENDENT  FORMALDEH YDE DEHYDR

OGENASE) ( EC 1.2.1.1 ) (FDH).

 ANEVIKCKAA VAWEAGKPLS IEEIEVAPPK

AHEVRIKIIA TAVCHTDAYT LSGADPEGCF

 PVILGHEGAG IVESVGEGVT

KLKAGDTVIP LYIPQCGECK FCLNPKTNLC QKIRVTQGKG

 LMPDGTSRFT

CKGKTILHYM GTSTFSEYTV VADISVAKID PLAPLDKVCL LGCGISTGYG

AAVNTAKLEP GSVCAVFGLG GVGLAVIMGC KVAGASRIIG VDINKDKFAR AKEFGATECI

 NPQDFSKPIQ EVLIEMTDGG VDYSFECIGN VKVMRAALEA CHKGWGVSVV

VGVAASGEEI

 ATRPFQLVTG RTWKGTAFGG WKSVESVPKL VSEYMSKKIK

VDEFVTHNLS FDEINKAFEL

 MHSGKSIRTV VKI

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     348 - 351  NLSF

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

     126 - 128  TsR

     130 - 132  TcK

     185 - 187  TaK

     309 - 311  TgR

     312 - 314  TwK

     336 - 338  SkK

     363 - 365  SgK

     366 - 368  SiR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       20 - 23  SieE

       52 - 55  SgaD

       74 - 77  SvgE

     144 - 147  TfsE

     296 - 299  SgeE

     350 - 353  SfdE

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       70 - 75  GIveSV

     172 - 177  GCgiST

     174 - 179  GIstGY

     180 - 185  GAavNT

     191 - 196  GSvcAV

     201 - 206  GVglAV

     209 - 214  GCkvAG

     220 - 225  GVdiNK

     235 - 240  GAteCI

     260 - 265  GVdySF

     292 - 297  GVaaSG

     315 - 320  GTafGG

     319 - 324  GGwkSV

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       65 - 79  GHEgaGivesvGegV

29 hits with 5 PROSITE entries

ADH 6

>SW:ADH6_H UMAN P2833 2 ALCOHOL  DEHYDROGEN ASE 6 (EC  1.1.1.1).

MSTTGQVIRC KAAILWKPGA PFSIEEVEVA PPKAKEVRIK VVATGLCGTE MKVLGSKHLD

 LLYPTILGHE GAGIVESIGE GVSTVKPGDK VITLFLPQCG ECTSCLNSEG

NFCIQFKQSK

 TQLMSDGTSR FTCKGKSIYH FGNTSTFCEY TVIKEISVAK

IDAVAPLEKV CLISCGFSTG

 FGAAINTAKV TPGSTCAVFG LGGVGLSVVM

GCKAAGAARI IGVDVNKEKF KKAQELGATE

 CLNPQDLKKP IQEVLFDMTD

AGIDFCFEAI GNLDVLAAAL ASCNESYGVC VVVGVLPASV

 QLKISGQLFF

SGRSLKGSVF GGWKSRQHIP KLVADYMAEK LNLDPLITHT LNLDKINEAV

ELMKTGKW

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     143 - 146  NTST

     284 - 287  NESY

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       84 - 86  TvK

     128 - 130  TsR

     132 - 134  TcK

     187 - 189  TaK

     311 - 313  SgR

     314 - 316  SlK

     365 - 367  TgK

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       23 - 26  SieE

       77 - 80  SigE

     146 - 149  TfcE

     282 - 285  ScnE

>PDOC00007 PS00007 TYR_PHOSPHO_SITE Tyrosine kinase phosphorylation site [pattern].

       57 - 63  Khl.Dll.Y

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       19 - 24  GApfSI

       45 - 50  GLcgTE

       73 - 78  GIveSI

     142 - 147  GNtsTF

     182 - 187  GAaiNT

     193 - 198  GStcAV

     203 - 208  GVglSV

     211 - 216  GCkaAG

     222 - 227  GVdvNK

     237 - 242  GAteCL

     262 - 267  GIdfCF

     294 - 299  GVlpAS

     317 - 322  GSvfGG

     321 - 326  GGwkSR

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       68 - 82  GHEgaGivesiGegV

29 hits with 6 PROSITE entries

ADH 7

>SW:ADH7_H UMAN P4039 4 ALCOHOL  DEHYDROGEN ASE CLASS  IV MU/SIGM

A CHAIN (E C 1.1.1.1)  (RETINOL  DEHYDROGEN ASE) (GAST RIC ALCOHO

L DEHYDROG ENASE).

 MGTAGKVIKC KAAVLWEQKQ PFSIEEIEVA PPKTKEVRIK

ILATGICRTD DHVIKGTMVS

 KFPVIVGHEA TGIVESIGEG VTTVKPGDKV

IPLFLPQCRE CNACRNPDGN LCIRSDITGR

 GVLADGTTRF TCKGKPVHHF

MNTSTFTEYT VVDESSVAKI DDAAPPEKVC LIGCGFSTGY

 GAAVKTGKVK

PGSTCVVFGL GGVGLSVIMG CKSAGASRII GIDLNKDKFE KAMAVGATEC

ISPKDSTKPI SEVLSEMTGN NVGYTFEVIG HLETMIDALA SCHMNYGTSV VVGVPPSAKM

 LTYDPMLLFT GRTWKGCVFG GLKSRDDVPK LVTEFLAKKF DLDQLITHVL

PFKKISEGFE

 LLNSGQSIRT VLTF

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

     142 - 145  NTST

>PDOC00003 PS00003 SULFATION Tyrosine sulfation site [rule].

     142 - 156  ntstfteYtvvdess

>PDOC00004 PS00004 CAMP_PHOSPHO_SITE cAMP- and cGMP-dependent protein kinase phosphorylation site [pattern].

     353 - 356  KKiS

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       83 - 85  TvK

     118 - 120  TgR

     127 - 129  TtR

     131 - 133  TcK

     186 - 188  TgK

     242 - 244  SpK

     246 - 248  StK

     297 - 299  SaK

     310 - 312  TgR

     313 - 315  TwK

     367 - 369  SiR

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

       23 - 26  SieE

       76 - 79  SigE

     145 - 148  TftE

     150 - 153  TvvD

     242 - 245  SpkD

     274 - 277  TmiD

     324 - 327  SrdD

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       45 - 50  GIcrTD

       56 - 61  GTmvSK

       72 - 77  GIveSI

     173 - 178  GCgfST

     202 - 207  GVglSV

     210 - 215  GCksAG

     221 - 226  GIdlNK

     236 - 241  GAteCI

     259 - 264  GNnvGY

     293 - 298  GVppSA

     316 - 321  GCvfGG

     320 - 325  GGlkSR

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       67 - 81  GHEatGivesiGegV

34 hits with 7 PROSITE entries

SORBITOL DEHYDROGENASE

>SW:DHSO_H UMAN Q0079 6 SORBITOL  DEHYDROGE NASE (EC 1 .1.1.14) (

L-IDITOL 2 -DEHYDROGE NASE).

 AAAAKPNNLS LVVHGPGDLR LENYPIPEPG

PNEVLLRMHS VGICGSDVHY WEYGRIGNFI

 VKKPMVLGHE ASGTVEKVGS

SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA

 TPPDDGNLCR

FYKHNAAFCY KLPDNVTFEE GALIEPLSVG IHACRRGGVT LGHKVLVCGA

GPIGMVTLLV AKAMGAAQVV VTDLSATRLS KAKEIGADLV LQISKESPQE IARKVEGLLG

 CKPEVTIECT GAEASIQAGI YATRSGGTLV LVGLGSEMTT VPLLHAAIRE

VDIKGVFRYC

 NTWPVAISML ASKSVNVKPL VTHRFPLEKA LEAFETFKKG

LGLKIMLKCD PSDQNP

PROSITE Release 17.3, of 12-Feb-2002

>PDOC00001 PS00001 ASN_GLYCOSYLATION N-glycosylation site [pattern].

        8 - 11  NLSL

     145 - 148  NVTF

>PDOC00005 PS00005 PKC_PHOSPHO_SITE Protein kinase C phosphorylation site [pattern].

       81 - 83  SvK

     322 - 324  ThR

     336 - 338  TfK

>PDOC00006 PS00006 CK2_PHOSPHO_SITE Casein kinase II phosphorylation site [pattern].

     121 - 124  TppD

     147 - 150  TfeE

     227 - 230  SpqE

     250 - 253  TgaE

>PDOC00008 PS00008 MYRISTYL N-myristoylation site [pattern].

       42 - 47  GIcgSD

     160 - 165  GIhaCR

     168 - 173  GVtlGH

     237 - 242  GLlgCK

     251 - 256  GAeaSI

     259 - 264  GIyaTR

     275 - 280  GSemTT

>PDOC00058 PS00059 ADH_ZINC Zinc-containing alcohol dehydrogenases signature [pattern].

       68 - 82  GHEasGtvekvGssV

17 hits with 5 PROSITE entries