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LOCUS NP_536735 454 aa linear INV 27-DEC-2001
DEFINITION Cyclin-dependent kinase 8 [Drosophila melanogaster].
ACCESSION NP_536735
PID g17981713
VERSION NP_536735.1 GI:17981713
DBSOURCE REFSEQ: accession NM_080487.1
KEYWORDS .
SOURCE fruit fly.
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
REFERENCE 1 (residues 1 to 454)
AUTHORS Leclerc,V., Tassan,J.P., O'Farrell,P.H., Nigg,E.A. and Leopold,P.
TITLE Drosophila Cdk8, a kinase partner of cyclin C that interacts with
the large subunit of RNA polymerase II
JOURNAL Mol. Biol. Cell 7 (4), 505-513 (1996)
MEDLINE 96282985
REFERENCE 2 (residues 1 to 454)
AUTHORS Bennett,D., Szoor,B. and Alphey,L.
TITLE The chaperone-like properties of mammalian inhibitor-2 are
conserved in a Drosophila homologue
JOURNAL Biochemistry 38 (49), 16276-16282 (1999)
MEDLINE 20056048
PUBMED 10587451
REFERENCE 3 (residues 1 to 454)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
MEDLINE 20196006
PUBMED 10731132
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from U33015.1.
FEATURES Location/Qualifiers
source 1..454
/organism="Drosophila melanogaster"
/db_xref="taxon:7227"
/chromosome="3"
/map="67C2"
Protein 1..454
/product="Cyclin-dependent kinase 8"
/EC_number="2.7.1.37"
/EC_number="2.7.1.-"
Region 24..335
/region_name="Serine/Threonine protein kinases, catalytic
domain"
/db_xref="CDD:smart00220"
/note="S_TKc"
Region 24..229
/region_name="Tyrosine kinase, catalytic domain"
/db_xref="CDD:smart00219"
/note="TyrKc"
Region 26..335
/region_name="Protein kinase domain"
/db_xref="CDD:pfam00069"
/note="pkinase"
CDS 1..454
/gene="Cdk8"
/db_xref="FLYBASE:FBgn0015618;"
/db_xref="LocusID:39157"
/coded_by="NM_080487.1:82..1446"
/note="cyclin dependent kinase"
ORIGIN
1 mdydfkmkaq iertnvedlf nyegckvgrg tyghvyrakr ketsdgkeya lkqidgtgls
61 msacreialw relkhqnvit lirvflshnd rkvfllidya ehdlwhiikf hraakatkkq
121 vvvprgmvks llyqildgih ylhsnwvlhr dlkpanilvm gdgnergrvk iadmgfarlf
181 naplkpladl dpvvvtfwyr apelllgarh ytkaidiwai gcifaellts epifhcrqed
241 iktsnpyhhd qldrifnvmg fpqdkdwedi kkmpehhtlt kdfkrstyst cslakymerh
301 kikpdskafh llqklllmdp ikritseqam qdqyfreepq ptqdvfagcp ipypkreflt
361 dddqedksdn krqqqqqqqq qqqqqqqqqq qqqqqqqqqq mnaepnakrv rlsgagnqqd
421 fhhqqqqqqq qqqqqqqqqq qmmfnqqqnf qrfn
//
Revised: October 24, 2001.
