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LOCUS NP_511044 353 aa linear INV 12-DEC-2001
DEFINITION Cyclin-dependent kinase 7 [Drosophila melanogaster].
ACCESSION NP_511044
PID g17530793
VERSION NP_511044.1 GI:17530793
DBSOURCE REFSEQ: accession NM_078489.1
KEYWORDS .
SOURCE fruit fly.
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
REFERENCE 1 (residues 1 to 353)
AUTHORS Larochelle,S., Pandur,J., Fisher,R.P., Salz,H.K. and Suter,B.
TITLE Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase
activity
JOURNAL Genes Dev. 12 (3), 370-381 (1998)
MEDLINE 98119834
PUBMED 9450931
REFERENCE 2 (residues 1 to 353)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor
Miklos,G.L., Abril,J.F., Agbayani,A., An,H.J.,
Andrews-Pfannkoch,C., Baldwin,D., Ballew,R.M., Basu,A.,
Baxendale,J., Bayraktaroglu,L., Beasley,E.M., Beeson,K.Y.,
Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S., Borkova,D.,
Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P., Burtis,K.C.,
Busam,D.A., Butler,H., Cadieu,E., Center,A., Chandra,I.,
Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B., Davies,P., de
Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I., Dietz,S.M.,
Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S., Dunkov,B.C.,
Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C., Ferriera,S.,
Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., Woodage,T.,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
MEDLINE 20196006
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from AE003433.2.
FEATURES Location/Qualifiers
source 1..353
/organism="Drosophila melanogaster"
/db_xref="taxon:7227"
/chromosome="1"
/map="4F1-4F2"
Protein 1..353
/product="Cyclin-dependent kinase 7"
/EC_number="2.7.1.37"
/EC_number="2.7.1.-"
Region 12..295
/region_name="Protein kinase domain"
/db_xref="CDD:pfam00069"
/note="pkinase"
Region 12..295
/region_name="Serine/Threonine protein kinases, catalytic
domain"
/db_xref="CDD:smart00220"
/note="S_TKc"
Region 18..207
/region_name="Tyrosine kinase, catalytic domain"
/db_xref="CDD:smart00219"
/note="TyrKc"
CDS 1..353
/gene="Cdk7"
/db_xref="FLYBASE:FBgn0015617;"
/db_xref="LocusID:31441"
/coded_by="NM_078489.1:35..1096"
/note="Nucleotide sequence of the Celera sequence differs
from the published sequence for this transcript."
ORIGIN
1 mlpnandkte ryaklsflge gqfatvykar dtvtnqivav kkikkgsred ardginrtal
61 reikilqelq heniiglvdv fgqlsnvslv fdfmdtdlev iikdnkiilt qanikayaim
121 tlkgleylhl nwilhrdlkp nnllvnsdgi lkigdfglak sfgspnriyt hhvvtrwyrs
181 pellfgarqy gtgvdmwavg cilaelmlrv pfmpgdsdld qltrifstlg tpteaewphl
241 sklhdylqfr nfpgtpldni ftaagndlih lmqrlfamnp lrrvscreal smpyfankpa
301 ptvgpklpmp sailaakega npqtgdtkpa lkrklvettv rgnglaqkkr lqf
//
Revised: October 24, 2001.