ID hamncdk'sfamily; BLOCK
AC hamncdkB; distance from previous
block=(17,22)
DE family
BL GRL motif=[8,0,17] motomat=[1,1,-10]
width=25 seqs=10
CDK1
( 42) EGVPSTAIREISLLKELRHPNIVSL 45
CDK10
( 77) DGIPISSLREITLLLRLRHPNIVEL 68
CDK2
( 42) EGVPSTAIREISLLKELNHPNIVKL 50
CDK3
( 42) EGVPSTAIREISLLKELKHPNIVRL 43
CDK4
( 47) GGLPISTVREVALLRRLEAFEHPNV 96
CDK5
( 42) EGVPSSALREICLLKELKHKNIVRL 52
CDK6
( 52) EGMPLSTIREVAVLRHLETFEHPNV 100
CDK7
( 53) DGINRTALREIKLLQELSHPNIIGL 70
CDK8
( 57) TGISMSACREIALLRELKHPNVISL 73
CDK9
( 57) EGFPITALREIKILQLLKHENVVNL 71
//
ID hamncdk'sfamily; BLOCK
AC hamncdkC; distance from previous
block=(8,16)
DE family
BL LDL motif=[8,0,17] motomat=[1,1,-10]
width=13 seqs=10
CDK1
( 75) RLYLIFEFLSMDL 83
CDK10
( 112) SIFLVMGYCEQDL 100
CDK2
( 75) KLYLVFEFLHQDL 53
CDK3
( 75) KLYLVFEFLSQDL 46
CDK4
( 88) KVTLVFEHVDQDL 57
CDK5
( 75) KLTLVFEFCDQDL 45
CDK6
( 93) KLTLVFEHVDQDL 52
CDK7
( 86) NISLVFDFMETDL 84
CDK8
( 92) KVWLLFDYAEHDL 90
CDK9
( 98) SIYLVFDFCEHDL 57
//
ID hamncdk'sfamily; BLOCK
AC hamncdkD; distance from previous
block=(15,23)
DE family
BL RDN motif=[8,0,17] motomat=[1,1,-10]
width=50 seqs=10
CDK1
( 105) VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG 43
CDK10
( 140) VKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYG 65
CDK2
( 104) IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 40
CDK3
( 104) IKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFG 44
CDK4
( 117) IKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYS 54
CDK5
( 103) VKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFG 46
CDK6
( 122) IKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYS 47
CDK7
( 114) IKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFG 59
CDK8
( 128) VKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFA 100
CDK9
( 126) IKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS 67
//
ID hamncdk'sfamily; BLOCK
AC hamncdkE; distance from previous
block=(7,16)
DE family
BL DGE motif=[8,0,17] motomat=[1,1,-10]
width=50 seqs=10
CDK1
( 164) VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQL 67
CDK10
( 199) VVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQI 78
CDK2
( 163) VVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQL 59
CDK3
( 163) VVTLWYRAPEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQL 54
CDK4
( 174) VVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQL 82
CDK5
( 162) VVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQ 100
CDK6
( 179) VVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQL 86
CDK7
( 173) VVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQL 78
CDK8
( 194) VVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKT 89
CDK9
( 189) VVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL 88
//
ID hamncdk'sfamily; BLOCK
AC hamncdkF; distance from previous
block=(46,66)
DE family
BL LPF motif=[8,0,17] motomat=[1,1,-10]
width=26 seqs=10
CDK1
( 262) DLLSKMLIYDPAKRISGKMALNHPYF 56
CDK10
( 298) RLLHFLFMYDPKKRATAGDCLESSYF 100
CDK2
( 261) SLLSQMLHYDPNKRISAKAALAHPFF 61
CDK3
( 261) DLLMQLLQYDPSQRITAKTALAHPYF 54
CDK4
( 270) QLLLEMLTFNPHKRISAFRALQHSYL 74
CDK5
( 261) DLLQNLLKCNPVQRISAEEALQHPYF 58
CDK6
( 275) DLLLKCLTFNPAKRISAYSALSHPYF 58
CDK7
( 270) DLIQGLFLFNPCARITATQALKMKYF 86
CDK8
( 310) HLLQKLLTMDPIKRITSEQAMQDPYF 74
CDK9
( 290) DLIDKLLVLDPAQRIDSDDALNHDFF 82
//
ID hamncdk'sfamily; BLOCK
AC hamncdkA; distance from previous
block=(3,38)
DE family
BL XXX motif=[8,0,0] motomat=[1,1,-15]
width=34 seqs=10
CDK1
( 4) YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRL 48
CDK10
( 39) FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRM 52
CDK2
( 4) FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRL 33
CDK3
( 4) FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRL 35
CDK4
( 6) YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRV 56
CDK5
( 4) YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRL 39
CDK6
( 13) YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVR 74
CDK7
( 12) YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKL 63
CDK8
( 21) EYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQI 100
CDK9
( 19) YEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLM 46
//
ID hamncdk'sfamily; BLOCK
AC hamncdkB; distance from previous
block=(2,7)
DE family
BL XXX motif=[8,0,0] motomat=[1,1,-15]
width=25 seqs=10
CDK1
( 42) EGVPSTAIREISLLKELRHPNIVSL 45
CDK10
( 77) DGIPISSLREITLLLRLRHPNIVEL 68
CDK2
( 42) EGVPSTAIREISLLKELNHPNIVKL 50
CDK3
( 42) EGVPSTAIREISLLKELKHPNIVRL 43
CDK4
( 47) GGLPISTVREVALLRRLEAFEHPNV 96
CDK5
( 42) EGVPSSALREICLLKELKHKNIVRL 52
CDK6
( 52) EGMPLSTIREVAVLRHLETFEHPNV 100
CDK7
( 53) DGINRTALREIKLLQELSHPNIIGL 70
CDK8
( 57) TGISMSACREIALLRELKHPNVISL 73
CDK9
( 57) EGFPITALREIKILQLLKHENVVNL 71
//
ID hamncdk'sfamily; BLOCK
AC hamncdkC; distance from previous
block=(36,46)
DE family
BL XXX motif=[8,0,0] motomat=[1,1,-15]
width=50 seqs=10
CDK1
( 105) VKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFG 43
CDK10
( 140) VKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYG 65
CDK2
( 104) IKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFG 40
CDK3
( 104) IKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFG 44
CDK4
( 117) IKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYS 54
CDK5
( 103) VKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFG 46
CDK6
( 122) IKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYS 47
CDK7
( 114) IKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFG 59
CDK8
( 128) VKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFA 100
CDK9
( 126) IKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFS 67
//
ID hamncdk'sfamily; BLOCK
AC hamncdkD; distance from previous
block=(8,16)
DE family
BL XXX motif=[8,0,0] motomat=[1,1,-15]
width=14 seqs=10
CDK1
( 164) VVTLWYRSPEVLLG 76
CDK10
( 199) VVTLWYRAPELLLG 61
CDK2
( 163) VVTLWYRAPEILLG 65
CDK3
( 163) VVTLWYRAPEILLG 65
CDK4
( 175) VVTLWYRAPEVLLQ 70
CDK5
( 162) VVTLWYRPPDVLFG 100
CDK6
( 180) VVTLWYRAPEVLLQ 70
CDK7
( 173) VVTRWYRAPELLFG 86
CDK8
( 194) VVTFWYRAPELLLG 76
CDK9
( 189) VVTLWYRPPELLLG 67
//
ID hamncdk'sfamily; BLOCK
AC hamncdkE; distance from previous
block=(15,25)
DE family
BL XXX motif=[8,0,0] motomat=[1,1,-15]
width=42 seqs=10
CDK1
( 194) FAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQ 47
CDK10
( 229) LAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLP 57
CDK2
( 193) FAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMP 36
CDK3
( 193) FAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLP 37
CDK4
( 204) FAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP 41
CDK5
( 193) AELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLP 57
CDK6
( 209) FAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP 48
CDK7
( 203) LAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLP 47
CDK8
( 233) IFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMP 100
CDK9
( 219) MAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYE 81
//
ALPHABET= ARNDCQEGHILKMFPSTWYVBZX
log-odds matrix: alength= 23 w= 13
-4.062 -6.486 -6.967 -7.047 -2.237 -6.696 -7.506
-7.283 -6.185 8.643 2.827
-6.120 -0.155 -1.821 -7.384 -6.597 -3.736 -5.316
-4.041 3.654 -7.010 -7.195
-3.659
-4.620 -8.268 -5.317 -6.699 -6.632 -7.975 -8.698
10.834 -6.960 -9.622 -9.957
-7.215 -8.747 -8.771 -8.885 -6.179 -7.560 -8.340
-9.439 -9.072 -6.067 -8.421
-5.970
-3.117 2.731 -2.388 -0.443 -4.584
3.415 7.631 -4.722 -1.419 -3.852 -4.700
-0.583 -3.524 -5.260 -4.867 -3.121 -3.465 -5.184
-4.348 0.031 -1.332 6.012
-1.896
-4.620 -8.268 -5.317 -6.699 -6.632 -7.975 -8.698
10.834 -6.960 -9.622 -9.957
-7.215 -8.747 -8.771 -8.885 -6.179 -7.560 -8.340
-9.439 -9.072 -6.067 -8.421
-5.970
2.615 -3.241 -2.649 -3.689 -2.114
3.884 -3.290 -3.624 -3.554 -3.118 -4.081
-2.760 -3.074 -4.927 -4.741 -1.425 8.120
-5.473 -4.643 -2.272 -3.213 -0.535
-1.795
-5.915 -6.039 -6.364 -7.613 -5.351 -6.251 -6.951
-7.353 -0.651 -3.744 -3.662
-6.288 -3.638 7.572 -8.360 -6.805 -6.166
0.053 11.850 -4.284 -7.042 -6.682
-4.327
2.499 -6.278 -3.805 -5.027 -4.241 -5.982
-6.563 9.684 -5.137 -7.065 -7.509
-5.247 -6.441 -6.793 -6.755 -3.995 -5.361 -6.585
-7.275 -6.214 -4.468 -6.340
-3.846
-2.098 -2.389 -2.339 -2.784 -1.781 -2.298
0.881 -4.162 5.004 2.223 -1.782
0.683 -1.444 -2.887 -4.649 -2.186 4.599
-4.440 -2.597 3.451 -2.580 -0.340
-1.182
-5.106 -8.460 -9.065 -9.459 -4.140 -8.572 -9.109
-9.169 -9.100 -0.253 -3.353
-8.333 -3.528 -5.354 -9.481 -8.098 -5.358 -8.270
-6.647 10.564 -9.279 -8.903
-6.342
-5.924 -6.059 -6.378 -7.619 -5.344 -6.284 -6.970
-7.352 -0.693 -3.722 -3.631
-6.312 -3.621 7.716 -8.379 -6.816 -6.172
0.028 11.781 -4.275 -7.051 -6.707
-4.328
-4.341 3.656 -3.343 -4.172 -5.892 -1.757
-2.670 -5.108 -3.291 -6.296 -6.344
9.825 -4.838 -7.137 -5.626 -4.317 -4.603 -6.706
-5.646 -6.042 -3.793 -2.319
-3.166
8.837 -5.319 -5.170 -5.439 -2.099 -5.014
-5.128 2.076 -4.832 -4.539 -5.233
-4.365 -4.517 -5.880 -5.334 -2.411 -3.734 -6.585
-5.752 -3.099 -5.316 -5.084
-2.926
-4.983 9.848 -3.522 -4.927 -6.178 -2.022
-3.456 -5.812 -2.980 -6.750 -6.144
5.631 -4.845 -6.826 -6.542 -4.799 -4.946 -6.395
-5.619 -6.192 -4.285 -2.905
-3.388
log-odds matrix: alength= 23 w= 25
-2.950 -2.839 -1.568 4.848 -4.413 -1.055
6.772 2.391 -1.997 -5.392 -5.818
-1.734 -4.567 -5.573 -4.797 -2.635 1.227
-5.520 -5.085 -4.723 1.914 3.766
-1.635
-4.620 -8.268 -5.317 -6.699 -6.632 -7.975 -8.698
10.834 -6.960 -9.622 -9.957
-7.215 -8.747 -8.771 -8.885 -6.179 -7.560 -8.340
-9.439 -9.072 -6.067 -8.421
-5.970
-3.042 -5.122 -5.842 -6.207 -1.515 -5.255 -6.191
-6.086 -4.630 5.602 2.644
-5.057 5.345 3.296 -6.614 -5.367
-2.959 -3.653 -1.922 4.800 -6.040 -5.832
-2.679
-3.143 -4.650 2.331 -3.592 -4.018 -4.505
-4.302 -4.274 -3.803 -5.712 -6.341
-3.517 -5.537 -6.757 10.463 0.671
-3.456 -8.233 -5.861 -5.366 -0.883 -4.380
-2.935
-2.133 1.524 -3.323 -4.233 -1.726 -3.522
-4.348 -4.260 -3.417 5.270 2.081
-2.767 4.198 -1.923 -5.443 2.953
-1.975 -4.506 -3.469 0.429 -3.817 -4.031
-1.246
-2.049 -4.306 -2.534 -3.784 -2.768 -4.099 -4.324
-3.813 -4.219 -4.673 -5.610
-3.719 -4.352 -5.674 -5.304 7.181
6.971 -6.489 -5.574 -3.856 -3.212 -4.238
-2.500
6.820 -4.115 -3.414 -4.131 -1.411 -3.888
-4.082 -2.316 -3.963 -3.345 -4.219
-3.353 -3.413 -4.874 -4.475 1.523
5.087 -5.689 -4.781 -2.155 -3.803 -4.007
-1.869
-3.444 -5.709 -6.489 -6.777 6.875 -6.047
-6.920 -6.523 -5.630 5.991 4.791
-5.645 0.368 -1.402 -6.905 -5.863 -3.457
-4.811 -3.698 3.410 -6.645 -6.585
-3.059
-7.057 11.758 -5.358 -7.064 -8.066 -3.899
-5.611 -7.921 -4.604 -8.723 -7.813
-1.718 -6.603 -8.450 -8.775 -6.786 -6.863 -8.019
-7.362 -8.016 -6.284 -4.954
-5.320
-6.128 -4.920 -5.167 -2.441 -8.287 -2.664
10.756 -7.660 -4.158 -8.944 -8.822
-3.729 -7.401 -8.671 -7.539 -5.857 -6.627 -8.240
-7.583 -7.974 -3.688 5.602
-4.866
-4.486 -7.346 -7.645 -7.731 -2.892 -7.458 -8.166
-7.951 -7.125 9.072 -0.796
-6.881 -1.290 -2.924 -8.061 -7.145 -4.244 -6.295
-4.886 5.748 -7.692 -7.894
-4.526
4.842 -1.750 -2.387 -3.134 5.583
-2.364 -2.745 -1.936 -2.829 -3.270 -3.919
3.292 -2.940 -4.496 -3.884 2.700
1.565 -5.147 -4.157 -2.241 -2.793 -2.599
-1.090
-4.137 -5.669 -7.048 -7.427 -2.215 -6.172 -7.137
-7.184 -5.844 3.348 7.113
-5.929 0.605 -1.288 -7.465 -6.632 -4.126
-4.849 -3.845 3.208 -7.254 -6.767
-3.456
-7.061 -8.021 -9.714 -10.155 -4.878 -8.642 -9.721
-9.818 -8.205 -1.791 9.211
-8.461 -1.570 -3.506 -10.130 -9.413 -7.051 -7.163
-6.305 -3.118 -9.953 -9.307
-5.599
-3.518 6.980 -2.427 -3.448 -4.378
4.952 -1.672 -4.489 -1.747 -4.009 -0.362
5.118 -2.488 -4.833 -5.212 -3.516 -3.557 -5.046
-4.096 -4.017 -2.981 0.872
-1.647
-3.603 4.923 -2.308 -1.213 -4.698 -0.638
6.404 -4.848 6.395 -4.285 -0.413
-0.662 -3.007 -4.267 -5.231 -3.525 -3.914 -4.827
-3.075 -4.267 -1.713 3.699
-1.531
-7.061 -8.021 -9.714 -10.155 -4.878 -8.642 -9.721
-9.818 -8.205 -1.791 9.211
-8.461 -1.570 -3.506 -10.130 -9.413 -7.051 -7.163
-6.305 -3.118 -9.953 -9.307
-5.599
-2.555 4.100 1.710 -1.063 -4.091
-0.273 4.417 -3.458 -1.301 -5.095 -5.074
5.465 -3.608 -5.284 -4.313 0.542 -2.637
-5.086 -4.175 -4.503 0.205 2.616
-1.295
1.482 -3.093 -1.895 -3.774 -3.947 -2.789
-3.309 -4.055 12.833 -5.025 -5.388
-3.372 -3.852 -3.823 -5.705 -3.273 2.348
-4.638 -0.656 -4.742 -2.914 -3.109
-2.416
-3.565 -3.734 -4.318 -3.668 -3.983 -3.777
0.784 -4.859 -3.205 -3.759 -3.734
0.300 -3.625 6.406 8.521 -4.208 -4.057
-4.032 -1.237 -4.112 -3.965 -0.967
-1.999
-5.130 -3.470 10.207 -0.933 -5.906 -2.688
5.110 -3.846 -1.777 -7.138 -7.538
-2.950 -6.058 -6.664 -6.500 -3.370 -3.935 -7.097
-5.987 -6.666 4.162 2.115
-3.125
-3.969 -5.044 -4.467 -5.680 -2.862 -4.921 -5.565
-6.296 9.092 7.122 -1.104
-5.090 -1.295 -2.497 -6.959 -5.716 -3.947 -5.117
-2.280 4.281 -5.125 -5.318
-3.121
-3.139 -5.871 -6.114 -6.072 -2.397 -5.886 -6.114
-6.208 -5.829 4.733 -1.514
-5.178 -1.746 -3.443 6.314 -5.356 -3.368
-6.376 -4.601 6.628 -6.091 -6.026
-3.202
-2.195 2.976 6.806 -0.549 -3.324
-1.354 1.057 1.777 -0.805 -5.108 -5.347
1.216 -3.876 -4.825 -4.570 1.886 -1.878
-5.107 -4.236 -4.539 2.815 0.131
-1.090
-4.636 -6.390 -7.758 -8.184 -2.893 -6.867 -7.778
-7.862 -6.694 0.475 7.265
-6.668 -0.304 -2.217 -8.175 -7.229 -4.727 -5.705
-4.648 5.222 -7.989 -7.428
-4.152
log-odds matrix: alength= 23 w= 13
-2.351 3.534 3.254 -2.251 -3.693
-1.161 -1.913 -3.105 -1.838 -5.090 -5.273
6.846 -3.736 -5.471 -4.478 2.949 -2.278
-5.514 -4.438 -4.619 0.267 -1.624
-1.500
-3.924 -6.029 -6.959 -7.207 -2.159 -6.375 -7.231
-7.168 -6.055 6.379 5.224
-5.996 0.151 -1.645 -7.375 -6.499 -3.811
-5.127 -3.954 4.496 -7.094 -6.902
-3.466
-2.899 -3.923 -3.282 -4.514 -2.786 -4.019 -4.486
-4.337 -0.671 -2.543 -2.799
-3.837 -2.406 4.978 -5.724 0.708
3.454 8.892 8.042 -2.586 -3.950 -4.307
-1.773
-7.061 -8.021 -9.714 -10.155 -4.878 -8.642 -9.721
-9.818 -8.205 -1.791 9.211
-8.461 -1.570 -3.506 -10.130 -9.413 -7.051 -7.163
-6.305 -3.118 -9.953 -9.307
-5.599
-2.968 -5.959 -6.661 -7.007 -1.775 -6.144 -6.777
-6.799 -6.385 4.171 2.147
-5.858 -0.579 -2.391 -7.078 -5.845 -3.119 -5.521
-4.054 8.187 -6.849 -6.534
-3.669
-6.157 -6.898 -7.073 -7.813 -4.644 -7.772 -7.935
-7.227 -4.260 -2.263 -1.725
-7.392 6.123 11.568 -9.319 -7.203
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log-odds matrix: alength= 23 w= 26
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======================CUT HERE==============================
**MAST Searchable
PSSMS from GIBBS**
======================CUT HERE==============================
ALPHABET= ARNDCQEGHILKMFPSTWYVBZX
log-odds matrix: alength= 23 w= 34
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