ClustalW. Múltiple séquense
aligment
C : conserved cysteine
X : conserved pattern
X : domain
AFAM_RAT
MRHLKLTGFIFFLLSLTESLALPTKPQDVDHFNATQKFINENVAYLTIIASAQYVQEASF
60
AFAM_MOUSE
MRHLKLTGFIFFLLPLTESLALPTKPQDVDHFNATQKFIDENTAYLAIIAFSQYVQEASF
60
AFAM_HUMAN
MKLLKLTGFIFFLFFLTESLTLPTQPRDIENFNSTQKFIEDNIEYITIIAFAQYVQEATF
60
*: **********: *****: ***:*:*:::**:*****::* *::*** :******:*
AFAM_RAT
EEVEMLVKVMLDYKDRCLADSTLPECSKIANDAIQDMLCDMKGLPQKHNFSHCCRQAGFQ 120
AFAM_MOUSE
DEVETLVKVMLDYRDRCWADNTLPECSKTANDAIQDMLCDMEGLPQKHNFSHCCGKAGFP 120
AFAM_HUMAN
EEMEKLVKDMVEYKDRCMADKTLPECSKLPNNVLQEKICAMEGLPQKHNFSHCCSKVDAQ 120
:*:* *** *::*:*** **.******* .*:.:*: :* *:************ :..
AFAM_RAT
RRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNNSESFLNLYMYEVARRNPFAFAPVLLN 180
AFAM_MOUSE
RRLCFFYNKKANVGFLPPFPTLDPEEKCQAYKNKSESFLHLYMYEVARRNPFVFAPVLLA 180
AFAM_HUMAN
RRLCFFYNKKSDVGFLPPFPTLDPEEKCQAYESNRESLLNHFLYEVARRNPFVFAPTLLT 180
**********::*******************:.: **:*: ::*********.***.**
AFAM_RAT
VAARFEEAATTCCEQQQKATYFQDKAAPITQYLKALSSYQRNVCGALLKFGPKTLNSINI 240
AFAM_MOUSE
VAAWFEEAATTCCEQQQKATCFQAKAAPITQYLKASSSYQRNVCGALIKFGPKVLNSINV 240
AFAM_HUMAN
VAVHFEEVAKSCCEEQNKVNCLQTRAIPVTQYLKAFSSYQKHVCGALLKFGTKVVHFIYI 240
**. ***.*.:***:*:*.. :* :* *:****** ****::*****:***.*.:: * :
AFAM_RAT
AVFSKKFPKIGFEDLTSLLEDVSSMYDGCCEGDVVQCIRSQSQVMHHICSKQDSISSKIK
300
AFAM_MOUSE
AVFSKKFPKIGFKDLTTLLEDVSSMYEGCCEGDVVHCIRSQSQVENHICSKQDSISSKIK
300
AFAM_HUMAN
AILSQKFPKIEFKELISLVEDVSSNYDGCCEGDVVQCIRDTSKVMNHICSKQDSISSKIK
300
*::*:***** *::* :*:***** *:********:***.
*:* :**************
AFAM_RAT
ACCEKKLPERADCIINANKDDRPEDLSLRTPKFTDSENVCQERDSEQDKFFAEFLYDYSR 360
AFAM_MOUSE
VCCEKKTLEREACIINANKDDRPEGLSLREAKFTESENVCQERDSDPDKFFAEFIYEYSR 360
AFAM_HUMAN
ECCEKKIPERGQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR 360
***** ** ****:******:.**** ***:*********:: *.***:* ::***
AFAM_RAT
RHTELSTPELLRITKVYKDLLEDCCNRKNPLSCYRHAEDKFNETTERSLAMVQQECKQFQ
420
AFAM_MOUSE
RHPDLSTPRLLRITKVYMDFLEDCCSRENPAGCYRHVEDKFNETTQRSLAMVQQECNQFQ
420
AFAM_HUMAN
RHPDLSIPELLRIVQIYKDLLRNCCNTENPPGCYRYAEDKFNETTEKSLKMVQQECKHFQ
420
**.:** *.****.::* *:*.:**. :** .***:.********::** ******::**
AFAM_RAT
ELGKDALQRHFLVKFTKAAPQLPMEELVSLSKEMVAALATCCTLSDEFACVDNLADLVLG 480
AFAM_MOUSE
ELGKDTLQRHFLVKFTKAAPQLPMEELVSLSKEMVAALTTCCTLSDEFACVDNLADLVLG 480
AFAM_HUMAN
NLGKDGLKYHYLIRLTKIAPQLSTEELVSLGEKMVTAFTTCCTLSEEFACVDNLADLVFG 480
:**** *: *:*:::** ****. ******.::**:*::******:************:*
AFAM_RAT
ELCGMNKNRTINPTVDHCCRADFAFRRPCFEHLKADTTYALPSVSALVSALRADWCQPLK 540
AFAM_MOUSE
ELCGVNTNRTINPAVDHCCKTDFAFRRHCFEHLKADTTYALPSVSALVSALHTDWCQPRK 540
AFAM_HUMAN
ELCGVNENRTINPAVDHCCKTNFAFRRPCFESLKADKTYVPPPFSQDLFTFHADMCQSQN 540
****:* ******:*****:::***** ***
****.**. *..* : ::::* **. :
AFAM_RAT
EDLQNKRHRFLVNLVKWMPEITDEERLCLFTKFTAAGEECGNIQKPEACFSPESSKTGDV 600
AFAM_MOUSE
EDLQNKKHRFLVNLVKWMPGITDEEWLCLFTKFTAAREECSEVQEPESCFSPESSKTGDE 600
AFAM_HUMAN
EELQRKTDRFLVNLVKLKHELTDEELQSLFTNFANVVDKCCKAESPEVCFNEESPKIGN- 599
*:**.* .******** :****
.***:*: . ::* : :.** **. **.* *:
AFAM_RAT SQDAEKQR---
608
AFAM_MOUSE SQATENKITDQ 611
AFAM_HUMAN
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